Is myopathy a side effect of PRAVACHOL ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of PRAVACHOL patients who developed myopathy.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 45 individuals taking PRAVACHOL reported myopathy to the FDA. A total of 9426 PRAVACHOL drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between PRAVACHOL and myopathy. In doing so, we compare PRAVACHOL with other drugs that cause myopathy, to help you evaluate whether or not PRAVACHOL causes myopathy. Likewise, this page shows the most highly-reported side effects of PRAVACHOL, so you can see if myopathy ranks among PRAVACHOL's most well-known side effects.

Summary Statistics
Reports of PRAVACHOL causing myopathy: 45
Reports of any side effect of PRAVACHOL : 9426
Percentage of PRAVACHOL patients where myopathy is a reported side effect: 0.4774%

FDA reports of any drug causing myopathy : 3605
Average percentage for all medicated patients where myopathy is reported as a complication: 0.0226%

Physician opinion on PRAVACHOL as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing PRAVACHOL:

BLOOD CHOLESTEROL INCREASED ( 1075 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 217 patients )
BLOOD CHOLESTEROL ( 211 patients )
DRUG USE FOR UNKNOWN INDICATION ( 209 patients )
HYPERCHOLESTEROLAEMIA ( 186 patients )
HYPERLIPIDAEMIA ( 180 patients )
BLOOD CHOLESTEROL ABNORMAL ( 40 patients )
DYSLIPIDAEMIA ( 21 patients )
BLOOD TRIGLYCERIDES INCREASED ( 21 patients )
HYPERTENSION ( 19 patients )
LOW DENSITY LIPOPROTEIN INCREASED ( 10 patients )
BLOOD CHOLESTEROL DECREASED ( 10 patients )
ILL-DEFINED DISORDER ( 10 patients )
PROPHYLAXIS ( 10 patients )
CORONARY ARTERY DISEASE ( 10 patients )
LIPIDS INCREASED ( 10 patients )
MYOCARDIAL INFARCTION ( 9 patients )
METABOLIC DISORDER ( 8 patients )
CARDIAC DISORDER ( 8 patients )
CARDIOVASCULAR DISORDER ( 8 patients )
ARTERIOSCLEROSIS ( 6 patients )
GOUT ( 5 patients )
DIABETES MELLITUS ( 3 patients )
PAIN ( 3 patients )
CORONARY ARTERIAL STENT INSERTION ( 3 patients )
RHABDOMYOLYSIS ( 3 patients )
STENT PLACEMENT ( 2 patients )
CAROTID ARTERY DISEASE ( 2 patients )
CEREBROVASCULAR ACCIDENT PROPHYLAXIS ( 2 patients )
RENAL FAILURE ACUTE ( 2 patients )
TRANSIENT ISCHAEMIC ATTACK ( 2 patients )
CAROTID ARTERY OCCLUSION ( 2 patients )
CEREBROVASCULAR ACCIDENT ( 2 patients )
CARDIAC OPERATION ( 1 patients )
LOW DENSITY LIPOPROTEIN ( 1 patients )
TYPE 2 DIABETES MELLITUS ( 1 patients )
CARDIOVASCULAR EVENT PROPHYLAXIS ( 1 patients )
GASTROOESOPHAGEAL REFLUX DISEASE ( 1 patients )
ANTIINFLAMMATORY THERAPY ( 1 patients )
GLUCOSE TOLERANCE IMPAIRED ( 1 patients )
CAROTID ARTERY STENOSIS ( 1 patients )
MIXED HYPERLIPIDAEMIA ( 1 patients )
CEREBRAL HAEMORRHAGE ( 1 patients )
BLOOD HOMOCYSTEINE INCREASED ( 1 patients )
KNEE ARTHROPLASTY ( 1 patients )
LIPID METABOLISM DISORDER ( 1 patients )
CORONARY ARTERY SURGERY ( 1 patients )
SCHIZOPHRENIA ( 1 patients )
LIVER DISORDER ( 1 patients )
LOW DENSITY LIPOPROTEIN DECREASED ( 1 patients )
ELECTROMYOGRAM ( 1 patients )
ULCER ( 1 patients )
CARDITIS ( 1 patients )
MENTAL DISORDER ( 1 patients )
ANGIOPLASTY ( 1 patients )
GLOBAL AMNESIA ( 1 patients )
MITRAL VALVE PROLAPSE ( 1 patients )
CEREBRAL ATHEROSCLEROSIS ( 1 patients )
POSTOPERATIVE CARE ( 1 patients )
CHOLESTEROSIS ( 1 patients )
BLOOD PRESSURE ( 1 patients )
LABORATORY TEST ABNORMAL ( 1 patients )
C-REACTIVE PROTEIN ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with myopathy:

LIPITOR (517 patients)
ZOCOR (480 patients)
ASPIRIN (474 patients)
SIMVASTATIN (410 patients)
FOSAMAX (309 patients)
PREDNISONE (241 patients)
CRESTOR (239 patients)
ZOMETA (201 patients)
PREDNISOLONE (199 patients)
LASIX (177 patients)
FUROSEMIDE (162 patients)
ZETIA (153 patients)
HYDROCHLOROTHIAZIDE (144 patients)
PREDNISONE TAB (139 patients)
LEVOTHYROXINE SODIUM (138 patients)
VIOXX (130 patients)
ALLOPURINOL (125 patients)
DEXAMETHASONE (124 patients)
INSULIN (120 patients)
COUMADIN (118 patients)
CYCLOSPORINE (113 patients)
ATENOLOL (112 patients)
ATORVASTATIN CALCIUM (110 patients)
NORVASC (108 patients)
CLARITHROMYCIN (107 patients)
AMBIEN (104 patients)
MYCOPHENOLATE MOFETIL (103 patients)
LISINOPRIL (99 patients)
NOROXIN (98 patients)
DECADRON (97 patients)
OMEPRAZOLE (97 patients)
POTASSIUM CHLORIDE (96 patients)
SORAFENIB (RAF KINASE INHIBITOR) (95 patients)
GABAPENTIN (94 patients)
SYNTHROID (94 patients)
LAMIVUDINE (90 patients)
AMLODIPINE (90 patients)
RAMIPRIL (89 patients)
NEXIUM (88 patients)
PRILOSEC (87 patients)
METHYLPREDNISOLONE (85 patients)
WARFARIN SODIUM (83 patients)
ZIDOVUDINE (82 patients)
ALBUTEROL (82 patients)
LANSOPRAZOLE (80 patients)
MEK INHIBITOR (DIHYDROXYPROP-DIFLU-METHOXYPHEN-CYCLOPROPA-SULFAMI) (80 patients)
PROTONIX (79 patients)
ACETAMINOPHEN (77 patients)
FOLIC ACID (77 patients)
MULTI-VITAMINS (75 patients)
XANAX (75 patients)
COZAAR (73 patients)
NEURONTIN (73 patients)
REMICADE (71 patients)
REVLIMID (69 patients)
HUMIRA (68 patients)
AMIODARONE HCL (67 patients)
FLONASE (65 patients)
CELEXA (64 patients)
FERROUS SULFATE TAB (64 patients)
ATORVASTATIN (64 patients)
AMLODIPINE BESYLATE (64 patients)
SPIRONOLACTONE (63 patients)
MAGNEVIST (62 patients)
VYTORIN (62 patients)
ZOLOFT (61 patients)
PEPCID (60 patients)
PROGRAF (60 patients)
CITALOPRAM HYDROBROMIDE (59 patients)
VICODIN (59 patients)
ADVAIR DISKUS 100/50 (59 patients)
ULTRAVIST 150 (59 patients)
PLAVIX (59 patients)
METHOTREXATE (58 patients)
COLCHICINE (58 patients)
AREDIA (57 patients)
OXYCONTIN (57 patients)
LYRICA (57 patients)
DIDANOSINE (56 patients)
ENALAPRIL MALEATE (55 patients)
HEPARIN SODIUM INJECTION (55 patients)
TAMOXIFEN CITRATE (55 patients)
ACYCLOVIR (52 patients)
FENOFIBRATE (52 patients)
PRAVASTATIN (52 patients)
CLONAZEPAM (51 patients)
ITRACONAZOLE (51 patients)
CYCLOPHOSPHAMIDE (51 patients)
DIGOXIN (49 patients)
SEBIVO (49 patients)
TOPROL-XL (49 patients)
LORAZEPAM (48 patients)
DILTIAZEM (48 patients)
LORTAB (48 patients)
ELAVIL (47 patients)
DIFLUCAN (47 patients)
METOPROLOL TARTRATE (46 patients)
ATIVAN (46 patients)
VELCADE (45 patients)
ALENDRONATE SODIUM (45 patients)
VITAMIN D (45 patients)
KLOR-CON (45 patients)
PRAVACHOL (45 patients)
WELLBUTRIN (44 patients)
TRICOR (44 patients)
DARVOCET-N 100 (44 patients)
PERCOCET (44 patients)
RAPAMUNE (43 patients)
ASCORBIC ACID (43 patients)
LEVAQUIN (43 patients)
AROMASIN (43 patients)
DIAZEPAM (43 patients)
ZANTAC (43 patients)
GEMFIBROZIL (41 patients)
CELEBREX (41 patients)
OXYCODONE HCL (41 patients)
ABACAVIR (40 patients)
LEXAPRO (40 patients)
NIFEDIPINE (40 patients)
RADIATION THERAPY (39 patients)
ACETYLSALICYLIC ACID SRT (39 patients)
ACIPHEX (39 patients)
METFORMIN HCL (39 patients)
IRON (39 patients)
ALTACE (39 patients)
TACROLIMUS (38 patients)
EFAVIRENZ (38 patients)
ZYPREXA (38 patients)
ZYRTEC (38 patients)
LESCOL (37 patients)
[THERAPY UNSPECIFIED] (37 patients)
METOPROLOL (37 patients)
GLEEVEC (37 patients)
PANTOPRAZOLE SODIUM (36 patients)
FOSAMAX PLUS D (36 patients)
PROPRANOLOL HYDROCHLORIDE (36 patients)
EFFEXOR (36 patients)
AMIODARONE (36 patients)
CEFTRIAXONE (36 patients)
HERCEPTIN (35 patients)
THALIDOMIDE (35 patients)
FUSIDIC ACID (35 patients)
SINGULAIR (35 patients)
IBUPROFEN (35 patients)
SPIRIVA (35 patients)
LOSARTAN POTASSIUM (35 patients)
VANCOMYCIN (35 patients)
WARFARIN (34 patients)
PERIDEX (34 patients)
BISOPROLOL (34 patients)
HYZAAR (34 patients)
SIROLIMUS (34 patients)
SOLU-MEDROL (34 patients)
ALPRAZOLAM (34 patients)
CO-TRIMOXAZOLE (34 patients)
AMITRIPTYLINE HCL (34 patients)
COREG (34 patients)
VITAMINS (UNSPECIFIED) (33 patients)
ACETYLSALICYLIC ACID (33 patients)
AZATHIOPRINE (33 patients)
ZOFRAN (33 patients)
CALTRATE +D (33 patients)
PROTEINASE INHIBITORS (33 patients)
CARTIA /USA/ (33 patients)
NIASPAN (33 patients)
PANTOPRAZOLE (33 patients)
MEGESTROL ACETATE (32 patients)
COMPAZINE (32 patients)
ADENOSINE (32 patients)
ALDACTONE (32 patients)
LANTUS (32 patients)
GASMOTIN (32 patients)
PROZAC (32 patients)
ARIMIDEX (31 patients)
AVELOX (31 patients)
FENTANYL (31 patients)
CALCIUM (UNSPECIFIED) (31 patients)
PAXIL (31 patients)
GLIPIZIDE (31 patients)
FLUCONAZOLE (31 patients)
ARANESP (31 patients)
CLARITIN (31 patients)
DILAUDID (31 patients)
NEUPOGEN (31 patients)
AVANDIA (31 patients)
B12 ^RECIP^ (30 patients)
K-DUR (30 patients)
CALCIUM CARBONATE (30 patients)
CELLCEPT (30 patients)
METFORMIN (30 patients)
CLOPIDOGREL (30 patients)
TRAMADOL HCL (30 patients)
REQUIP (29 patients)
CARVEDILOL (29 patients)
GLUCOPHAGE (29 patients)
FLOMAX (29 patients)
ZESTRIL (29 patients)
MIRTAZAPINE (29 patients)
TIAZAC (29 patients)
CAPECITABINE (29 patients)
KETEK (29 patients)
NICORANDIL (29 patients)
VERAPAMIL (29 patients)
CYMBALTA (28 patients)
RALTEGRAVIR (28 patients)
LOVASTATIN (28 patients)
CALCIUM (28 patients)
ACTOS (28 patients)
MICARDIS (28 patients)
DILTIAZEM HYDROCHLORIDE (28 patients)

Most common side effects for patients taking PRAVACHOL:

NAUSEA (805 patients)
PAIN (768 patients)
MYOCARDIAL INFARCTION (724 patients)
ANXIETY (708 patients)
DIZZINESS (700 patients)
DYSPNOEA (696 patients)
FATIGUE (660 patients)
CHEST PAIN (648 patients)
ASTHENIA (589 patients)
PAIN IN EXTREMITY (586 patients)
MYALGIA (527 patients)
HYPERTENSION (525 patients)
CORONARY ARTERY DISEASE (517 patients)
FALL (517 patients)
DEPRESSION (507 patients)
ARTHRALGIA (500 patients)
DRUG INEFFECTIVE (490 patients)
DIARRHOEA (480 patients)
OEDEMA PERIPHERAL (480 patients)
CARDIAC FAILURE CONGESTIVE (474 patients)
BACK PAIN (454 patients)
HEADACHE (440 patients)
CEREBROVASCULAR ACCIDENT (432 patients)
INJURY (431 patients)
VOMITING (407 patients)
ANAEMIA (401 patients)
WEIGHT DECREASED (372 patients)
RENAL FAILURE (358 patients)
PNEUMONIA (349 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (344 patients)
INSOMNIA (335 patients)
ABDOMINAL PAIN (333 patients)
HYPOTENSION (318 patients)
PYREXIA (310 patients)
EMOTIONAL DISTRESS (300 patients)
HYPOAESTHESIA (298 patients)
CONSTIPATION (295 patients)
OSTEOARTHRITIS (289 patients)
MUSCLE SPASMS (289 patients)
DEATH (286 patients)
BLOOD GLUCOSE INCREASED (280 patients)
URINARY TRACT INFECTION (277 patients)
BLOOD CHOLESTEROL INCREASED (270 patients)
ATRIAL FIBRILLATION (269 patients)
WEIGHT INCREASED (265 patients)
COUGH (263 patients)
DEHYDRATION (259 patients)
MALAISE (258 patients)
RENAL FAILURE ACUTE (240 patients)
NEUROPATHY PERIPHERAL (238 patients)
RASH (231 patients)
ANHEDONIA (230 patients)
CELLULITIS (227 patients)
GAIT DISTURBANCE (224 patients)
PARAESTHESIA (221 patients)
HYPERLIPIDAEMIA (220 patients)
DIABETES MELLITUS (219 patients)
CARDIAC DISORDER (218 patients)
BLOOD PRESSURE INCREASED (218 patients)
ANGINA PECTORIS (218 patients)
PLEURAL EFFUSION (215 patients)
BONE DISORDER (215 patients)
CONFUSIONAL STATE (208 patients)
DYSPEPSIA (206 patients)
FEELING ABNORMAL (204 patients)
SPINAL OSTEOARTHRITIS (201 patients)
MUSCULAR WEAKNESS (194 patients)
PRURITUS (193 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (190 patients)
PALPITATIONS (188 patients)
TRANSIENT ISCHAEMIC ATTACK (188 patients)
OSTEONECROSIS OF JAW (186 patients)
ABDOMINAL PAIN UPPER (186 patients)
DECREASED APPETITE (185 patients)
SYNCOPE (184 patients)
ROTATOR CUFF SYNDROME (181 patients)
ACUTE MYOCARDIAL INFARCTION (179 patients)
MITRAL VALVE INCOMPETENCE (179 patients)
SOMNOLENCE (176 patients)
CONDITION AGGRAVATED (175 patients)
LOSS OF CONSCIOUSNESS (173 patients)
PAIN IN JAW (170 patients)
CONVULSION (168 patients)
OSTEOPOROSIS (168 patients)
OSTEOMYELITIS (168 patients)
TREMOR (167 patients)
VISION BLURRED (163 patients)
DRY MOUTH (161 patients)
DYSPHAGIA (161 patients)
SINUSITIS (159 patients)
CONTUSION (159 patients)
HYPERHIDROSIS (159 patients)
GASTRITIS (153 patients)
CATARACT (153 patients)
BRONCHITIS (152 patients)
ERYTHEMA (149 patients)
HAEMOGLOBIN DECREASED (149 patients)
ARTHRITIS (149 patients)
BLOOD CREATININE INCREASED (148 patients)
OSTEOPENIA (147 patients)
ABDOMINAL DISTENSION (146 patients)
ASTHMA (145 patients)
BRADYCARDIA (145 patients)
UNEVALUABLE EVENT (144 patients)
MUSCULOSKELETAL PAIN (143 patients)
HIATUS HERNIA (143 patients)
DEEP VEIN THROMBOSIS (141 patients)
INTERVERTEBRAL DISC DEGENERATION (141 patients)
OSTEONECROSIS (140 patients)
HYPERCHOLESTEROLAEMIA (140 patients)
AMNESIA (140 patients)
CHEST DISCOMFORT (140 patients)
OEDEMA (137 patients)
SWELLING FACE (134 patients)
PHARMACEUTICAL PRODUCT COMPLAINT (133 patients)
HAEMORRHOIDS (133 patients)
ATELECTASIS (132 patients)
TRICUSPID VALVE INCOMPETENCE (130 patients)
FLUSHING (127 patients)
SWELLING (126 patients)
STRESS (125 patients)
HEART RATE INCREASED (125 patients)
CHILLS (122 patients)
SEPSIS (121 patients)
NECK PAIN (121 patients)
INTERVERTEBRAL DISC PROTRUSION (120 patients)
MYOCARDIAL ISCHAEMIA (119 patients)
INFECTION (119 patients)
GASTROINTESTINAL HAEMORRHAGE (119 patients)
VERTIGO (119 patients)
ALOPECIA (117 patients)
RECTAL HAEMORRHAGE (116 patients)
BURSITIS (116 patients)
CORONARY ARTERY OCCLUSION (115 patients)
RENAL IMPAIRMENT (115 patients)
DYSPHONIA (113 patients)
POLLAKIURIA (112 patients)
BONE PAIN (111 patients)
HYPERGLYCAEMIA (111 patients)
MEMORY IMPAIRMENT (110 patients)
RESPIRATORY FAILURE (110 patients)
THROMBOCYTOPENIA (110 patients)
PANCREATITIS (110 patients)
CHOLELITHIASIS (109 patients)
DYSPNOEA EXERTIONAL (109 patients)
ARRHYTHMIA (109 patients)
HYPERSENSITIVITY (108 patients)
FEAR (108 patients)
BALANCE DISORDER (108 patients)
MENTAL STATUS CHANGES (108 patients)
TOOTH EXTRACTION (108 patients)
TOOTH DISORDER (106 patients)
ANGINA UNSTABLE (106 patients)
SCAR (105 patients)
DENTAL CARIES (104 patients)
PULMONARY EMBOLISM (103 patients)
CARDIOMEGALY (102 patients)
DIVERTICULUM (102 patients)
HYPOKALAEMIA (101 patients)
RENAL FAILURE CHRONIC (101 patients)
PERIPHERAL VASCULAR DISORDER (101 patients)
BLOOD TRIGLYCERIDES INCREASED (101 patients)
SLEEP APNOEA SYNDROME (101 patients)
CARDIAC ARREST (99 patients)
RENAL DISORDER (99 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (99 patients)
FOOT FRACTURE (98 patients)
HERPES ZOSTER (98 patients)
LETHARGY (98 patients)
DYSARTHRIA (98 patients)
STOMATITIS (97 patients)
DYSGEUSIA (97 patients)
ARTERIOSCLEROSIS (97 patients)
RENAL INJURY (96 patients)
ARTHROPATHY (96 patients)
LUMBAR SPINAL STENOSIS (95 patients)
LUNG DISORDER (95 patients)
HEART RATE IRREGULAR (95 patients)
DRUG HYPERSENSITIVITY (95 patients)
CARDIAC MURMUR (94 patients)
ADVERSE EVENT (94 patients)
NASAL CONGESTION (94 patients)
INFLUENZA (94 patients)
TYPE 2 DIABETES MELLITUS (93 patients)
BURNING SENSATION (93 patients)
OSTEOLYSIS (92 patients)
NERVOUSNESS (92 patients)
HEPATIC ENZYME INCREASED (92 patients)
MUSCULOSKELETAL STIFFNESS (92 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (91 patients)
UPPER RESPIRATORY TRACT INFECTION (90 patients)
DRUG INTERACTION (89 patients)
GINGIVITIS (89 patients)
JOINT SWELLING (89 patients)
EXOSTOSIS (89 patients)
BLOOD GLUCOSE DECREASED (89 patients)
NEPHROLITHIASIS (88 patients)
HAEMATOCRIT DECREASED (88 patients)
ERECTILE DYSFUNCTION (87 patients)
CARPAL TUNNEL SYNDROME (87 patients)
PULMONARY OEDEMA (87 patients)
PULMONARY HYPERTENSION (86 patients)
SLEEP DISORDER (86 patients)
RHINITIS ALLERGIC (85 patients)
BLOOD PRESSURE DECREASED (85 patients)
ALANINE AMINOTRANSFERASE INCREASED (84 patients)
THROMBOSIS (83 patients)
ECONOMIC PROBLEM (83 patients)
BENIGN PROSTATIC HYPERPLASIA (82 patients)
HYPONATRAEMIA (82 patients)

In addition to reviewing our up-to-date FDA research, users may interact with the FactMed community - currently one million members and growing! FactMed online research and discussions are read by patients, scientists, physicians, and other interested health care parties. Post follow up Questions to learn from our diverse readership. Likewise, patients who have experienced unwanted effects are encouraged to share their Concerns to help educate and inform our members.

Recent FactMed Activity for PRAVACHOL

Issue	Description / Topic	Timestamp
QUESTION LYMPHOCYTOSIS	Ive been on Pravachol 40mg per day since 2001 and i have constant lower back pain skin tightening on the feet fòot pain diabetesT2 blepharitis dry ryes b cell monoclonal lymphocytosis i belirve its these drugs but GP s wont take me off of them	2015-07-02 14:56:19
QUESTION LATEX ALLERGY	I have a severe latex allergy and my doctor wants to start me on Pravachol should I be concerned of a potential reaction	2016-01-19 20:44:10
QUESTION SNEEZING	These statins are poison. I had severe sneezing p 1st dose & 6 other side effects the 2nd day. What about informed consent r/t rhabomyolysis (I'm sure misspelled).	2016-01-26 16:35:12
QUESTION MYOCARDIAL ISCHAEMIA	Why waste money on soihnemtg Der Holy Mother Schtaat can now search and seize without warrant or pretext while throwing the owner in jail as long as it wants!?	2017-03-20 08:57:04

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