Study of possible correlation between ABASIA and SORAFENIB (RAF KINASE INHIBITOR)
Accompanying discussion about FactMed users Questions and Concerns
About this FactMed analysis covering adverse side effect reports of SORAFENIB (RAF KINASE INHIBITOR) patients who developed ABASIA.
FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 69 individuals taking SORAFENIB (RAF KINASE INHIBITOR) reported ABASIA to the FDA. A total of 3329 SORAFENIB (RAF KINASE INHIBITOR) drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.FDA Research Report
Introduction This page is designed to help you determine the relationship, if any, between SORAFENIB (RAF KINASE INHIBITOR) and ABASIA. In doing so, we compare SORAFENIB (RAF KINASE INHIBITOR) with other drugs that cause ABASIA, to help you evaluate whether or not SORAFENIB (RAF KINASE INHIBITOR) causes ABASIA. Likewise, this page shows the most highly-reported side effects of SORAFENIB (RAF KINASE INHIBITOR), so you can see if ABASIA ranks among SORAFENIB (RAF KINASE INHIBITOR)'s most well-known side effects.
Summary StatisticsReports of SORAFENIB (RAF KINASE INHIBITOR) causing ABASIA: 69
Reports of any side effect of SORAFENIB (RAF KINASE INHIBITOR) : 3329
Percentage of SORAFENIB (RAF KINASE INHIBITOR) patients where ABASIA is a reported side effect: 2.0727%
FDA reports of any drug causing ABASIA : 16416
Average percentage for all medicated patients where ABASIA is reported as a complication: 0.1029%
Physician opinion on SORAFENIB (RAF KINASE INHIBITOR) as adverse event culprit:
Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing SORAFENIB (RAF KINASE INHIBITOR):
HEPATIC NEOPLASM MALIGNANT
( 770 patients )RENAL CELL CARCINOMA ( 114 patients )
THYROID CANCER ( 65 patients )
METASTATIC RENAL CELL CARCINOMA ( 44 patients )
THYROID CANCER METASTATIC ( 35 patients )
BREAST CANCER ( 31 patients )
BREAST CANCER METASTATIC ( 27 patients )
GASTRIC CANCER ( 25 patients )
NON-SMALL CELL LUNG CANCER ( 25 patients )
COLORECTAL CANCER METASTATIC ( 22 patients )
RENAL CANCER ( 17 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 14 patients )
BILE DUCT CANCER ( 14 patients )
SALIVARY GLAND CANCER ( 7 patients )
HEPATIC CANCER METASTATIC ( 7 patients )
COLORECTAL CANCER ( 7 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 6 patients )
RECTAL CANCER ( 5 patients )
PANCREATIC CARCINOMA ( 4 patients )
PROSTATE CANCER ( 4 patients )
INTRAOCULAR MELANOMA ( 4 patients )
HEPATIC NEOPLASM MALIGNANT RECURRENT ( 3 patients )
NEOPLASM ( 3 patients )
LIVER DISORDER ( 3 patients )
ANGIOSARCOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 3 patients )
METASTASES TO LUNG ( 3 patients )
HEPATIC NEOPLASM MALIGNANT NON-RESECTABLE ( 3 patients )
COLORECTAL CANCER STAGE IV ( 3 patients )
NEOPLASM MALIGNANT ( 3 patients )
GALLBLADDER CANCER METASTATIC ( 3 patients )
METASTASIS ( 3 patients )
BILIARY CANCER METASTATIC ( 3 patients )
COLON CANCER METASTATIC ( 2 patients )
HYPOPHARYNGEAL CANCER ( 2 patients )
DESMOID TUMOUR ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
ACUTE MYELOID LEUKAEMIA (IN REMISSION) ( 2 patients )
OESOPHAGEAL CARCINOMA ( 2 patients )
METASTATIC MALIGNANT MELANOMA ( 2 patients )
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED ( 2 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
ANGINA PECTORIS ( 2 patients )
OSTEOSARCOMA METASTATIC ( 2 patients )
METASTATIC OCULAR MELANOMA ( 2 patients )
BONE SARCOMA ( 2 patients )
METASTATIC SALIVARY GLAND CANCER ( 2 patients )
TONSIL CANCER ( 2 patients )
MYELODYSPLASTIC SYNDROME ( 1 patients )
PROSTATE CANCER METASTATIC ( 1 patients )
GALLBLADDER CANCER ( 1 patients )
NEUROENDOCRINE TUMOUR ( 1 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 1 patients )
GLIOMA ( 1 patients )
BLADDER CANCER ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
CAROTID ARTERY DISEASE ( 1 patients )
HEPATOBLASTOMA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
RENAL CANCER METASTATIC ( 1 patients )
ACUTE MYELOID LEUKAEMIA ( 1 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 1 patients )
NEUROENDOCRINE CARCINOMA OF THE SKIN ( 1 patients )
MALIGNANT HISTIOCYTOSIS ( 1 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 1 patients )
SARCOMA ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
GERM CELL CANCER ( 1 patients )
OESOPHAGEAL ADENOCARCINOMA ( 1 patients )
SQUAMOUS CELL CARCINOMA ( 1 patients )
HEAD AND NECK CANCER ( 1 patients )
OVARIAN EPITHELIAL CANCER ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with ABASIA:
AVONEX (2153 patients)
TYSABRI (1202 patients)
ASPIRIN (1160 patients)
LIPITOR (972 patients)
FORTEO (700 patients)
HUMIRA (667 patients)
MAGNEVIST (652 patients)
LYRICA (647 patients)
LISINOPRIL (537 patients)
LASIX (527 patients)
SYNTHROID (514 patients)
BETASERON (503 patients)
REMICADE (497 patients)
NEXIUM (491 patients)
PREDNISONE (486 patients)
NEURONTIN (483 patients)
REBIF (452 patients)
SANDOSTATIN LAR (449 patients)
SEROQUEL (438 patients)
SIMVASTATIN (434 patients)
PLAVIX (428 patients)
LEVAQUIN (423 patients)
HEPARIN SODIUM INJECTION (414 patients)
CELEBREX (403 patients)
CRESTOR (402 patients)
XANAX (399 patients)
ZOCOR (392 patients)
COUMADIN (384 patients)
ATENOLOL (376 patients)
OMNISCAN (366 patients)
NORVASC (357 patients)
FUROSEMIDE (355 patients)
FOSAMAX (348 patients)
HYDROCHLOROTHIAZIDE (346 patients)
VITAMIN D (331 patients)
DIGOXIN (328 patients)
METHOTREXATE (318 patients)
OMEPRAZOLE (309 patients)
FOLIC ACID (306 patients)
TOPROL-XL (304 patients)
ENBREL (302 patients)
LEVOTHYROXINE SODIUM (299 patients)
IBUPROFEN (286 patients)
BACLOFEN (280 patients)
LANTUS (278 patients)
DIOVAN (269 patients)
VIOXX (267 patients)
AMBIEN (263 patients)
GABAPENTIN (260 patients)
PAXIL (257 patients)
VICODIN (256 patients)
CYMBALTA (253 patients)
NEXAVAR (249 patients)
WARFARIN SODIUM (242 patients)
CHANTIX (238 patients)
ZOLOFT (234 patients)
PROTONIX (233 patients)
RECLAST (231 patients)
CALCIUM (230 patients)
EPOGEN (226 patients)
LEXAPRO (225 patients)
ACETAMINOPHEN (222 patients)
ZOMETA (222 patients)
PRILOSEC (221 patients)
ALBUTEROL (220 patients)
ADVAIR DISKUS 100/50 (218 patients)
COREG (217 patients)
ALLOPURINOL (212 patients)
POTASSIUM CHLORIDE (211 patients)
OXYCONTIN (209 patients)
TOPAMAX (204 patients)
INSULIN (201 patients)
METFORMIN HCL (200 patients)
KLONOPIN (199 patients)
PREVACID (196 patients)
PREDNISONE TAB (196 patients)
ALPRAZOLAM (188 patients)
CLONAZEPAM (183 patients)
AMPYRA (183 patients)
LORAZEPAM (180 patients)
PROZAC (178 patients)
METOPROLOL TARTRATE (177 patients)
DIAZEPAM (175 patients)
REVLIMID (174 patients)
OPTIMARK (171 patients)
AVELOX (169 patients)
LORTAB (165 patients)
PERCOCET (164 patients)
ATIVAN (163 patients)
AMLODIPINE (163 patients)
EXELON (162 patients)
IRON (161 patients)
COZAAR (160 patients)
AVANDIA (154 patients)
DEPAKOTE (154 patients)
ZETIA (152 patients)
HUMALOG (149 patients)
CELEXA (149 patients)
RISPERDAL (146 patients)
VALTREX (145 patients)
CIPROFLOXACIN (145 patients)
MORPHINE (144 patients)
ZYPREXA (144 patients)
DURAGESIC-100 (142 patients)
EFFEXOR (140 patients)
GLUCOPHAGE (139 patients)
PREMARIN (137 patients)
ACTONEL (137 patients)
TRAMADOL HCL (136 patients)
VITAMIN B-12 (135 patients)
ARICEPT (135 patients)
OXYCODONE HCL (135 patients)
MULTI-VITAMINS (134 patients)
RENAGEL (133 patients)
NITROGLYCERIN (131 patients)
KLOR-CON (131 patients)
ASCORBIC ACID (129 patients)
MULTI-VITAMIN (129 patients)
TYLENOL (129 patients)
GADOLINIUM IN UNSPECIFIED DRUG (129 patients)
CALCIUM CARBONATE (127 patients)
ACTOS (127 patients)
DEXAMETHASONE (127 patients)
VALIUM (127 patients)
YAZ (126 patients)
KEPPRA (126 patients)
METFORMIN (125 patients)
SINGULAIR (125 patients)
CITALOPRAM HYDROBROMIDE (124 patients)
ALL OTHER THERAPEUTIC PRODUCTS (124 patients)
VITAMIN E (123 patients)
LAMICTAL (122 patients)
TYLENOL (CAPLET) (122 patients)
DILANTIN (122 patients)
LITHIUM CARBONATE (122 patients)
SPIRONOLACTONE (121 patients)
TEGRETOL (119 patients)
VYTORIN (118 patients)
PREDNISOLONE (118 patients)
TRAZODONE HCL (115 patients)
CLONIDINE (115 patients)
CARBAMAZEPINE (112 patients)
FLEXERIL (110 patients)
LANSOPRAZOLE (109 patients)
METOPROLOL (108 patients)
HYDROCODONE (107 patients)
COPAXONE (106 patients)
GLIPIZIDE (105 patients)
BENADRYL (104 patients)
LOPRESSOR (104 patients)
GLEEVEC (102 patients)
EFFEXOR XR (102 patients)
ACETYLSALICYLIC ACID SRT (102 patients)
BONIVA (100 patients)
ZOFRAN (100 patients)
AMITRIPTYLINE HCL (99 patients)
YASMIN (98 patients)
GLYBURIDE (97 patients)
ALTACE (97 patients)
FERROUS SULFATE TAB (95 patients)
PEG-INTRON (95 patients)
PROHANCE (95 patients)
VERAPAMIL (94 patients)
ZANTAC (94 patients)
FENTANYL (94 patients)
TRICOR (94 patients)
PROCRIT (94 patients)
FLOMAX (93 patients)
SENSIPAR (92 patients)
WELLBUTRIN (92 patients)
ARANESP (92 patients)
SOMA (91 patients)
MIRALAX (91 patients)
THALOMID (90 patients)
BEXTRA (90 patients)
RIBAVIRIN (89 patients)
ENALAPRIL MALEATE (89 patients)
DECADRON (89 patients)
FISH OIL (89 patients)
MULTIHANCE (89 patients)
RAMIPRIL (89 patients)
LIDODERM (88 patients)
MIRTAZAPINE (88 patients)
PROVIGIL (87 patients)
MOTRIN (86 patients)
AMIODARONE HCL (85 patients)
SPIRIVA (85 patients)
FLUOXETINE (85 patients)
PROGRAF (84 patients)
ALDACTONE (84 patients)
NAMENDA (84 patients)
LEVOXYL (83 patients)
COLACE (83 patients)
ALLEGRA (83 patients)
DARVOCET-N 100 (83 patients)
CARDIZEM (83 patients)
PAROXETINE HCL (83 patients)
REQUIP (82 patients)
NAPROXEN (82 patients)
LOVENOX (82 patients)
PHOSLO (82 patients)
LOSARTAN POTASSIUM (80 patients)
BYETTA (80 patients)
POTASSIUM (79 patients)
CARVEDILOL (79 patients)
FLONASE (79 patients)
CIPRO (79 patients)
REGLAN (77 patients)
ELAVIL (76 patients)
NIFEDIPINE (76 patients)
Most common side effects for patients taking SORAFENIB (RAF KINASE INHIBITOR):
DIARRHOEA (613 patients) HEPATIC FAILURE (378 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (342 patients)
HEPATIC ENCEPHALOPATHY (320 patients)
FATIGUE (300 patients)
RASH (276 patients)
ASCITES (253 patients)
ABDOMINAL PAIN (237 patients)
DECREASED APPETITE (226 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (198 patients)
PYREXIA (191 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (179 patients)
NAUSEA (165 patients)
HYPERTENSION (160 patients)
ASTHENIA (154 patients)
DEHYDRATION (140 patients)
HEPATIC FUNCTION ABNORMAL (133 patients)
DYSPNOEA (131 patients)
CONFUSIONAL STATE (131 patients)
HYPOKALAEMIA (125 patients)
ALOPECIA (124 patients)
VOMITING (118 patients)
CONSTIPATION (115 patients)
INTERSTITIAL LUNG DISEASE (114 patients)
LEFT VENTRICULAR DYSFUNCTION (113 patients)
DEATH (113 patients)
ENDOCARDITIS (112 patients)
ARTHRALGIA (111 patients)
STOMATITIS (111 patients)
ABDOMINAL PAIN UPPER (110 patients)
JAUNDICE (108 patients)
HEPATIC NEOPLASM MALIGNANT (106 patients)
GASTROINTESTINAL HAEMORRHAGE (106 patients)
RETINAL VASCULAR THROMBOSIS (103 patients)
LOWER GASTROINTESTINAL HAEMORRHAGE (103 patients)
LIVER CARCINOMA RUPTURED (101 patients)
OEDEMA PERIPHERAL (97 patients)
PLEURAL EFFUSION (97 patients)
STAPHYLOCOCCAL INFECTION (96 patients)
PNEUMONIA BACTERIAL (96 patients)
ENTEROBACTER INFECTION (96 patients)
MYOPATHY (95 patients)
DRY MOUTH (94 patients)
PAIN IN EXTREMITY (93 patients)
ANXIETY (90 patients)
MALAISE (89 patients)
PULMONARY EMBOLISM (85 patients)
ANAEMIA (84 patients)
PLATELET COUNT DECREASED (81 patients)
BACK PAIN (79 patients)
SEPSIS (78 patients)
PRURITUS (78 patients)
DUODENAL ULCER (77 patients)
MIGRAINE (76 patients)
MITRAL VALVE INCOMPETENCE (76 patients)
HYPOGLYCAEMIA (76 patients)
C-REACTIVE PROTEIN INCREASED (74 patients)
BLOOD PRESSURE INCREASED (73 patients)
VARICES OESOPHAGEAL (73 patients)
HEADACHE (72 patients)
RETINAL VEIN OCCLUSION (72 patients)
ABASIA (69 patients)
RENAL FAILURE ACUTE (69 patients)
WEIGHT DECREASED (67 patients)
DEEP VEIN THROMBOSIS (67 patients)
DIZZINESS (65 patients)
ERYTHEMA (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (64 patients)
CONVULSION (63 patients)
ALANINE AMINOTRANSFERASE INCREASED (62 patients)
DYSPHONIA (62 patients)
CEREBRAL HAEMORRHAGE (60 patients)
APHAGIA (58 patients)
COLITIS (58 patients)
PNEUMONIA (57 patients)
GASTRIC ULCER (56 patients)
HYPONATRAEMIA (55 patients)
HAEMOGLOBIN DECREASED (53 patients)
RESPIRATORY FAILURE (52 patients)
LUNG DISORDER (52 patients)
CEREBRAL ISCHAEMIA (49 patients)
PARAESTHESIA (49 patients)
BLOOD BILIRUBIN INCREASED (48 patients)
GAIT DISTURBANCE (48 patients)
THYROID CANCER METASTATIC (44 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (43 patients)
PERICARDIAL EFFUSION (41 patients)
THROMBOCYTOPENIA (41 patients)
BLISTER (41 patients)
FEBRILE NEUTROPENIA (40 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (40 patients)
HALLUCINATION (40 patients)
CHILLS (40 patients)
AMMONIA INCREASED (39 patients)
SKIN ULCER (39 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (38 patients)
PAIN (38 patients)
HYPOALBUMINAEMIA (38 patients)
HYPOCALCAEMIA (37 patients)
FALL (37 patients)
POLLAKIURIA (37 patients)
BLOOD PRESSURE DECREASED (37 patients)
SKIN EXFOLIATION (37 patients)
INSOMNIA (36 patients)
CARDIAC ARREST (36 patients)
HYPOAESTHESIA (35 patients)
INFECTIOUS PERITONITIS (35 patients)
MYOCARDIAL INFARCTION (35 patients)
RETINAL VASCULAR DISORDER (34 patients)
RENAL FAILURE (34 patients)
LIPASE INCREASED (34 patients)
HYPERKALAEMIA (33 patients)
HYPERGLYCAEMIA (33 patients)
HAEMOPTYSIS (31 patients)
ATRIAL FIBRILLATION (30 patients)
GENERALISED OEDEMA (30 patients)
FAECAL INCONTINENCE (30 patients)
WHITE BLOOD CELL COUNT DECREASED (30 patients)
CELLULITIS (29 patients)
CHEST PAIN (29 patients)
SOMNOLENCE (29 patients)
HYPERBILIRUBINAEMIA (28 patients)
HYPOTENSION (28 patients)
MUSCLE SPASMS (28 patients)
ABDOMINAL DISTENSION (27 patients)
WHITE BLOOD CELL COUNT INCREASED (27 patients)
VISION BLURRED (27 patients)
HEPATIC PAIN (26 patients)
BLOOD ALBUMIN DECREASED (26 patients)
DYSURIA (25 patients)
RASH GENERALISED (25 patients)
BLOOD SODIUM DECREASED (25 patients)
BLOOD URIC ACID INCREASED (25 patients)
COMA (25 patients)
COUGH (25 patients)
PANCYTOPENIA (25 patients)
ACUTE ABDOMEN (24 patients)
EOSINOPHIL COUNT INCREASED (24 patients)
CEREBROVASCULAR ACCIDENT (24 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (23 patients)
CEREBRAL INFARCTION (23 patients)
HYPOMAGNESAEMIA (23 patients)
RETINAL VEIN THROMBOSIS (23 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (23 patients)
TUMOUR LYSIS SYNDROME (22 patients)
HYPOPHOSPHATAEMIA (22 patients)
INFECTION (22 patients)
ORAL PAIN (22 patients)
BLOOD CREATININE INCREASED (22 patients)
NEUTROPENIA (22 patients)
RENAL IMPAIRMENT (22 patients)
LETHARGY (22 patients)
SKIN TOXICITY (21 patients)
TONGUE BLISTERING (21 patients)
LIVER ABSCESS (21 patients)
HAEMATEMESIS (21 patients)
OESOPHAGEAL VARICES HAEMORRHAGE (20 patients)
MENTAL IMPAIRMENT (20 patients)
NERVOUSNESS (20 patients)
NEPHROTIC SYNDROME (20 patients)
HYPOPHAGIA (20 patients)
ADRENAL INSUFFICIENCY (19 patients)
DRY SKIN (19 patients)
BLOOD AMYLASE INCREASED (19 patients)
OEDEMA (19 patients)
INFECTIOUS PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
COMA HEPATIC (19 patients)
HEART RATE INCREASED (18 patients)
HYPERTENSIVE CRISIS (18 patients)
MYALGIA (18 patients)
ECZEMA (18 patients)
URINARY TRACT INFECTION (18 patients)
NEUROMYOPATHY (18 patients)
MEDICAL DEVICE COMPLICATION (18 patients)
DIVERTICULITIS (18 patients)
OSTEOMYELITIS (18 patients)
CEREBRAL ATROPHY (18 patients)
CEREBRAL VENTRICLE DILATATION (18 patients)
DIABETIC FOOT INFECTION (18 patients)
NECK PAIN (18 patients)
OLIGURIA (17 patients)
GASTROINTESTINAL DISORDER (17 patients)
HAEMATOCHEZIA (17 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (17 patients)
HYPOTHYROIDISM (17 patients)
TRANSAMINASES INCREASED (17 patients)
OROPHARYNGEAL PAIN (17 patients)
CHRONIC MYELOID LEUKAEMIA (17 patients)
NEOPLASM PROGRESSION (17 patients)
METASTASES TO ADRENALS (16 patients)
LYMPHOCYTE COUNT DECREASED (16 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (16 patients)
MULTI-ORGAN FAILURE (16 patients)
FEAR (16 patients)
PANCREATIC CARCINOMA (16 patients)
HYPERSOMNIA (16 patients)
EPILEPSY (16 patients)
SUBARACHNOID HAEMORRHAGE (16 patients)
METASTASES TO LUNG (16 patients)
TACHYCARDIA (16 patients)
MUSCULAR WEAKNESS (16 patients)
KLEBSIELLA SEPSIS (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
DYSGEUSIA (16 patients)
LUNG INFECTION (16 patients)
FAECES DISCOLOURED (16 patients)
PAIN OF SKIN (16 patients)
SPINAL FRACTURE (16 patients)
PANIC REACTION (16 patients)
In addition to reviewing our up-to-date FDA research, users may interact with the FactMed community - currently one million members and growing! FactMed online research and discussions are read by patients, scientists, physicians, and other interested health care parties. Post follow up Questions to learn from our diverse readership. Likewise, patients who have experienced unwanted effects are encouraged to share their Concerns to help educate and inform our members.
Recent FactMed Activity for SORAFENIB (RAF KINASE INHIBITOR)
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