Is ABDOMINAL DISTENSION a side effect of SORAFENIB (RAF KINASE INHIBITOR) ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of SORAFENIB (RAF KINASE INHIBITOR) patients who developed ABDOMINAL DISTENSION.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 27 individuals taking SORAFENIB (RAF KINASE INHIBITOR) reported ABDOMINAL DISTENSION to the FDA. A total of 3329 SORAFENIB (RAF KINASE INHIBITOR) drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between SORAFENIB (RAF KINASE INHIBITOR) and ABDOMINAL DISTENSION. In doing so, we compare SORAFENIB (RAF KINASE INHIBITOR) with other drugs that cause ABDOMINAL DISTENSION, to help you evaluate whether or not SORAFENIB (RAF KINASE INHIBITOR) causes ABDOMINAL DISTENSION. Likewise, this page shows the most highly-reported side effects of SORAFENIB (RAF KINASE INHIBITOR), so you can see if ABDOMINAL DISTENSION ranks among SORAFENIB (RAF KINASE INHIBITOR)'s most well-known side effects.

Summary Statistics
Reports of SORAFENIB (RAF KINASE INHIBITOR) causing ABDOMINAL DISTENSION: 27
Reports of any side effect of SORAFENIB (RAF KINASE INHIBITOR) : 3329
Percentage of SORAFENIB (RAF KINASE INHIBITOR) patients where ABDOMINAL DISTENSION is a reported side effect: 0.8111%

FDA reports of any drug causing ABDOMINAL DISTENSION : 25551
Average percentage for all medicated patients where ABDOMINAL DISTENSION is reported as a complication: 0.1601%

Physician opinion on SORAFENIB (RAF KINASE INHIBITOR) as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing SORAFENIB (RAF KINASE INHIBITOR):

HEPATIC NEOPLASM MALIGNANT ( 770 patients )
RENAL CELL CARCINOMA ( 114 patients )
THYROID CANCER ( 65 patients )
METASTATIC RENAL CELL CARCINOMA ( 44 patients )
THYROID CANCER METASTATIC ( 35 patients )
BREAST CANCER ( 31 patients )
BREAST CANCER METASTATIC ( 27 patients )
GASTRIC CANCER ( 25 patients )
NON-SMALL CELL LUNG CANCER ( 25 patients )
COLORECTAL CANCER METASTATIC ( 22 patients )
RENAL CANCER ( 17 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 14 patients )
BILE DUCT CANCER ( 14 patients )
SALIVARY GLAND CANCER ( 7 patients )
HEPATIC CANCER METASTATIC ( 7 patients )
COLORECTAL CANCER ( 7 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 6 patients )
RECTAL CANCER ( 5 patients )
PANCREATIC CARCINOMA ( 4 patients )
PROSTATE CANCER ( 4 patients )
INTRAOCULAR MELANOMA ( 4 patients )
HEPATIC NEOPLASM MALIGNANT RECURRENT ( 3 patients )
NEOPLASM ( 3 patients )
LIVER DISORDER ( 3 patients )
ANGIOSARCOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 3 patients )
METASTASES TO LUNG ( 3 patients )
HEPATIC NEOPLASM MALIGNANT NON-RESECTABLE ( 3 patients )
COLORECTAL CANCER STAGE IV ( 3 patients )
NEOPLASM MALIGNANT ( 3 patients )
GALLBLADDER CANCER METASTATIC ( 3 patients )
METASTASIS ( 3 patients )
BILIARY CANCER METASTATIC ( 3 patients )
COLON CANCER METASTATIC ( 2 patients )
HYPOPHARYNGEAL CANCER ( 2 patients )
DESMOID TUMOUR ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
ACUTE MYELOID LEUKAEMIA (IN REMISSION) ( 2 patients )
OESOPHAGEAL CARCINOMA ( 2 patients )
METASTATIC MALIGNANT MELANOMA ( 2 patients )
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED ( 2 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
ANGINA PECTORIS ( 2 patients )
OSTEOSARCOMA METASTATIC ( 2 patients )
METASTATIC OCULAR MELANOMA ( 2 patients )
BONE SARCOMA ( 2 patients )
METASTATIC SALIVARY GLAND CANCER ( 2 patients )
TONSIL CANCER ( 2 patients )
MYELODYSPLASTIC SYNDROME ( 1 patients )
PROSTATE CANCER METASTATIC ( 1 patients )
GALLBLADDER CANCER ( 1 patients )
NEUROENDOCRINE TUMOUR ( 1 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 1 patients )
GLIOMA ( 1 patients )
BLADDER CANCER ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
CAROTID ARTERY DISEASE ( 1 patients )
HEPATOBLASTOMA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
RENAL CANCER METASTATIC ( 1 patients )
ACUTE MYELOID LEUKAEMIA ( 1 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 1 patients )
NEUROENDOCRINE CARCINOMA OF THE SKIN ( 1 patients )
MALIGNANT HISTIOCYTOSIS ( 1 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 1 patients )
SARCOMA ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
GERM CELL CANCER ( 1 patients )
OESOPHAGEAL ADENOCARCINOMA ( 1 patients )
SQUAMOUS CELL CARCINOMA ( 1 patients )
HEAD AND NECK CANCER ( 1 patients )
OVARIAN EPITHELIAL CANCER ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with ABDOMINAL DISTENSION:

ASPIRIN (1822 patients)
BYETTA (1590 patients)
SANDOSTATIN LAR (1573 patients)
HEPARIN SODIUM INJECTION (1464 patients)
NEXIUM (1275 patients)
HUMIRA (1211 patients)
LASIX (1023 patients)
ALLI (959 patients)
LIPITOR (945 patients)
SYNTHROID (907 patients)
CHANTIX (875 patients)
FOSAMAX (852 patients)
VIOXX (836 patients)
MIRENA (835 patients)
YAZ (826 patients)
PREDNISONE (784 patients)
YASMIN (741 patients)
LYRICA (738 patients)
LISINOPRIL (706 patients)
METFORMIN HCL (703 patients)
OMEPRAZOLE (677 patients)
FORTEO (666 patients)
FUROSEMIDE (628 patients)
PRILOSEC (625 patients)
XANAX (613 patients)
PROTONIX (606 patients)
ATENOLOL (588 patients)
COUMADIN (587 patients)
NEURONTIN (573 patients)
FOLIC ACID (553 patients)
DIANEAL (542 patients)
ALBUTEROL (541 patients)
NORVASC (519 patients)
CRESTOR (498 patients)
HYDROCHLOROTHIAZIDE (498 patients)
PREVACID (494 patients)
POTASSIUM CHLORIDE (489 patients)
SIMVASTATIN (488 patients)
ACETAMINOPHEN (487 patients)
LANTUS (486 patients)
METHOTREXATE (471 patients)
ZOCOR (468 patients)
DIGOXIN (459 patients)
AMBIEN (456 patients)
CYMBALTA (456 patients)
PLAVIX (450 patients)
ZOMETA (439 patients)
ZOLOFT (433 patients)
TOPROL-XL (428 patients)
ENBREL (416 patients)
LEVOTHYROXINE SODIUM (414 patients)
VITAMIN D (413 patients)
REMICADE (408 patients)
PAXIL (397 patients)
IBUPROFEN (396 patients)
CELEBREX (396 patients)
EXJADE (392 patients)
LORAZEPAM (387 patients)
GLUCOPHAGE (387 patients)
OXYCONTIN (378 patients)
AVANDIA (375 patients)
CALCIUM (374 patients)
ATIVAN (372 patients)
LEVAQUIN (372 patients)
DIOVAN (366 patients)
ZELNORM (364 patients)
LEXAPRO (363 patients)
SEROQUEL (363 patients)
ACTOS (363 patients)
GLEEVEC (344 patients)
ZOFRAN (332 patients)
SINGULAIR (328 patients)
INSULIN (326 patients)
PROZAC (320 patients)
ALPRAZOLAM (320 patients)
MULTI-VITAMINS (314 patients)
PREDNISONE TAB (314 patients)
DEXAMETHASONE (312 patients)
SPIRONOLACTONE (311 patients)
CLONAZEPAM (310 patients)
PREMARIN (309 patients)
AMARYL (307 patients)
MULTI-VITAMIN (307 patients)
VICODIN (306 patients)
METFORMIN (304 patients)
KLONOPIN (299 patients)
ADVAIR DISKUS 100/50 (291 patients)
COREG (287 patients)
ZANTAC (286 patients)
GLYBURIDE (286 patients)
PREDNISOLONE (282 patients)
WARFARIN SODIUM (277 patients)
ALLOPURINOL (275 patients)
MORPHINE (274 patients)
GABAPENTIN (265 patients)
GLIPIZIDE (264 patients)
METOPROLOL TARTRATE (263 patients)
ASCORBIC ACID (259 patients)
MIRALAX (256 patients)
DECADRON (256 patients)
ZETIA (254 patients)
TRAMADOL HCL (252 patients)
PERCOCET (251 patients)
ACCUTANE (249 patients)
FISH OIL (248 patients)
AMLODIPINE (247 patients)
CELEXA (240 patients)
PRADAXA (237 patients)
ZYRTEC (236 patients)
VITAMIN B-12 (232 patients)
WELLBUTRIN (230 patients)
SPIRIVA (229 patients)
PEGASYS (228 patients)
REGLAN (228 patients)
DROSPIRENONE AND ETHINYL ESTRADIOL (223 patients)
FENTANYL (222 patients)
OXYCODONE HCL (222 patients)
COZAAR (222 patients)
KALETRA (219 patients)
TYLENOL (219 patients)
CLONIDINE (218 patients)
PLAN B ONE-STEP (218 patients)
AREDIA (217 patients)
HUMALOG (217 patients)
EFFEXOR (217 patients)
VITAMIN E (217 patients)
RIBAVIRIN (216 patients)
ALDACTONE (213 patients)
LORTAB (213 patients)
AMOXICILLIN (211 patients)
RANITIDINE (207 patients)
METOCLOPRAMIDE (207 patients)
ALLEGRA (205 patients)
TRAZODONE HCL (204 patients)
FLONASE (203 patients)
LACTULOSE (203 patients)
VELCADE (201 patients)
VALIUM (200 patients)
AVONEX (199 patients)
MORPHINE SULFATE (196 patients)
METOPROLOL (196 patients)
COLACE (195 patients)
CIMZIA (195 patients)
ALTACE (195 patients)
NITROGLYCERIN (194 patients)
CYCLOPHOSPHAMIDE (194 patients)
LANSOPRAZOLE (193 patients)
BACTRIM (193 patients)
DIAZEPAM (193 patients)
CALCIUM CARBONATE (191 patients)
CIPROFLOXACIN (189 patients)
NIASPAN (186 patients)
LOPRESSOR (184 patients)
RISPERDAL (182 patients)
SOLIRIS (182 patients)
ENALAPRIL MALEATE (181 patients)
BENADRYL (179 patients)
BONIVA (177 patients)
TYLENOL (CAPLET) (176 patients)
VANCOMYCIN (175 patients)
NEXAVAR (174 patients)
JANUVIA (173 patients)
FLUOXETINE (172 patients)
LOVENOX (172 patients)
VYTORIN (172 patients)
LEVOXYL (171 patients)
ACIPHEX (171 patients)
XELODA (170 patients)
FAMOTIDINE (169 patients)
CLOZAPINE (169 patients)
ACTONEL (169 patients)
CLARITIN (169 patients)
CLOZARIL (168 patients)
AVASTIN (168 patients)
REBIF (167 patients)
PROMETHAZINE (167 patients)
TYSABRI (167 patients)
FLOMAX (166 patients)
TOPAMAX (165 patients)
NOVOLOG (164 patients)
AMITRIPTYLINE HCL (162 patients)
VICTOZA (162 patients)
KETEK (161 patients)
CARBOPLATIN (160 patients)
TRACLEER (160 patients)
VITAMINS (159 patients)
TRICOR (159 patients)
LAMIVUDINE (159 patients)
NAPROXEN (158 patients)
AMLODIPINE BESYLATE (157 patients)
FLUCONAZOLE (157 patients)
ALEVE (155 patients)
SANDOSTATIN (154 patients)
DILAUDID (154 patients)
FLUOROURACIL (153 patients)
ZYPREXA (152 patients)
CEPHALEXIN (152 patients)
PEPCID (151 patients)
FLEXERIL (150 patients)
MAGNESIUM (150 patients)
ALL OTHER THERAPEUTIC PRODUCTS (149 patients)
POTASSIUM (148 patients)
COMPAZINE (148 patients)
ACYCLOVIR (148 patients)
LUPRON DEPOT (147 patients)
PRAVACHOL (146 patients)
PAROXETINE HCL (144 patients)
CARVEDILOL (144 patients)
ZITHROMAX (143 patients)
DURAGESIC-100 (143 patients)

Most common side effects for patients taking SORAFENIB (RAF KINASE INHIBITOR):

DIARRHOEA (613 patients)
HEPATIC FAILURE (378 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (342 patients)
HEPATIC ENCEPHALOPATHY (320 patients)
FATIGUE (300 patients)
RASH (276 patients)
ASCITES (253 patients)
ABDOMINAL PAIN (237 patients)
DECREASED APPETITE (226 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (198 patients)
PYREXIA (191 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (179 patients)
NAUSEA (165 patients)
HYPERTENSION (160 patients)
ASTHENIA (154 patients)
DEHYDRATION (140 patients)
HEPATIC FUNCTION ABNORMAL (133 patients)
DYSPNOEA (131 patients)
CONFUSIONAL STATE (131 patients)
HYPOKALAEMIA (125 patients)
ALOPECIA (124 patients)
VOMITING (118 patients)
CONSTIPATION (115 patients)
INTERSTITIAL LUNG DISEASE (114 patients)
LEFT VENTRICULAR DYSFUNCTION (113 patients)
DEATH (113 patients)
ENDOCARDITIS (112 patients)
ARTHRALGIA (111 patients)
STOMATITIS (111 patients)
ABDOMINAL PAIN UPPER (110 patients)
JAUNDICE (108 patients)
HEPATIC NEOPLASM MALIGNANT (106 patients)
GASTROINTESTINAL HAEMORRHAGE (106 patients)
RETINAL VASCULAR THROMBOSIS (103 patients)
LOWER GASTROINTESTINAL HAEMORRHAGE (103 patients)
LIVER CARCINOMA RUPTURED (101 patients)
OEDEMA PERIPHERAL (97 patients)
PLEURAL EFFUSION (97 patients)
STAPHYLOCOCCAL INFECTION (96 patients)
PNEUMONIA BACTERIAL (96 patients)
ENTEROBACTER INFECTION (96 patients)
MYOPATHY (95 patients)
DRY MOUTH (94 patients)
PAIN IN EXTREMITY (93 patients)
ANXIETY (90 patients)
MALAISE (89 patients)
PULMONARY EMBOLISM (85 patients)
ANAEMIA (84 patients)
PLATELET COUNT DECREASED (81 patients)
BACK PAIN (79 patients)
SEPSIS (78 patients)
PRURITUS (78 patients)
DUODENAL ULCER (77 patients)
MIGRAINE (76 patients)
MITRAL VALVE INCOMPETENCE (76 patients)
HYPOGLYCAEMIA (76 patients)
C-REACTIVE PROTEIN INCREASED (74 patients)
BLOOD PRESSURE INCREASED (73 patients)
VARICES OESOPHAGEAL (73 patients)
HEADACHE (72 patients)
RETINAL VEIN OCCLUSION (72 patients)
ABASIA (69 patients)
RENAL FAILURE ACUTE (69 patients)
WEIGHT DECREASED (67 patients)
DEEP VEIN THROMBOSIS (67 patients)
DIZZINESS (65 patients)
ERYTHEMA (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (64 patients)
CONVULSION (63 patients)
ALANINE AMINOTRANSFERASE INCREASED (62 patients)
DYSPHONIA (62 patients)
CEREBRAL HAEMORRHAGE (60 patients)
APHAGIA (58 patients)
COLITIS (58 patients)
PNEUMONIA (57 patients)
GASTRIC ULCER (56 patients)
HYPONATRAEMIA (55 patients)
HAEMOGLOBIN DECREASED (53 patients)
RESPIRATORY FAILURE (52 patients)
LUNG DISORDER (52 patients)
CEREBRAL ISCHAEMIA (49 patients)
PARAESTHESIA (49 patients)
BLOOD BILIRUBIN INCREASED (48 patients)
GAIT DISTURBANCE (48 patients)
THYROID CANCER METASTATIC (44 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (43 patients)
PERICARDIAL EFFUSION (41 patients)
THROMBOCYTOPENIA (41 patients)
BLISTER (41 patients)
FEBRILE NEUTROPENIA (40 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (40 patients)
HALLUCINATION (40 patients)
CHILLS (40 patients)
AMMONIA INCREASED (39 patients)
SKIN ULCER (39 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (38 patients)
PAIN (38 patients)
HYPOALBUMINAEMIA (38 patients)
HYPOCALCAEMIA (37 patients)
FALL (37 patients)
POLLAKIURIA (37 patients)
BLOOD PRESSURE DECREASED (37 patients)
SKIN EXFOLIATION (37 patients)
INSOMNIA (36 patients)
CARDIAC ARREST (36 patients)
HYPOAESTHESIA (35 patients)
INFECTIOUS PERITONITIS (35 patients)
MYOCARDIAL INFARCTION (35 patients)
RETINAL VASCULAR DISORDER (34 patients)
RENAL FAILURE (34 patients)
LIPASE INCREASED (34 patients)
HYPERKALAEMIA (33 patients)
HYPERGLYCAEMIA (33 patients)
HAEMOPTYSIS (31 patients)
ATRIAL FIBRILLATION (30 patients)
GENERALISED OEDEMA (30 patients)
FAECAL INCONTINENCE (30 patients)
WHITE BLOOD CELL COUNT DECREASED (30 patients)
CELLULITIS (29 patients)
CHEST PAIN (29 patients)
SOMNOLENCE (29 patients)
HYPERBILIRUBINAEMIA (28 patients)
HYPOTENSION (28 patients)
MUSCLE SPASMS (28 patients)
ABDOMINAL DISTENSION (27 patients)
WHITE BLOOD CELL COUNT INCREASED (27 patients)
VISION BLURRED (27 patients)
HEPATIC PAIN (26 patients)
BLOOD ALBUMIN DECREASED (26 patients)
DYSURIA (25 patients)
RASH GENERALISED (25 patients)
BLOOD SODIUM DECREASED (25 patients)
BLOOD URIC ACID INCREASED (25 patients)
COMA (25 patients)
COUGH (25 patients)
PANCYTOPENIA (25 patients)
ACUTE ABDOMEN (24 patients)
EOSINOPHIL COUNT INCREASED (24 patients)
CEREBROVASCULAR ACCIDENT (24 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (23 patients)
CEREBRAL INFARCTION (23 patients)
HYPOMAGNESAEMIA (23 patients)
RETINAL VEIN THROMBOSIS (23 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (23 patients)
TUMOUR LYSIS SYNDROME (22 patients)
HYPOPHOSPHATAEMIA (22 patients)
INFECTION (22 patients)
ORAL PAIN (22 patients)
BLOOD CREATININE INCREASED (22 patients)
NEUTROPENIA (22 patients)
RENAL IMPAIRMENT (22 patients)
LETHARGY (22 patients)
SKIN TOXICITY (21 patients)
TONGUE BLISTERING (21 patients)
LIVER ABSCESS (21 patients)
HAEMATEMESIS (21 patients)
OESOPHAGEAL VARICES HAEMORRHAGE (20 patients)
MENTAL IMPAIRMENT (20 patients)
NERVOUSNESS (20 patients)
NEPHROTIC SYNDROME (20 patients)
HYPOPHAGIA (20 patients)
ADRENAL INSUFFICIENCY (19 patients)
DRY SKIN (19 patients)
BLOOD AMYLASE INCREASED (19 patients)
OEDEMA (19 patients)
INFECTIOUS PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
COMA HEPATIC (19 patients)
HEART RATE INCREASED (18 patients)
HYPERTENSIVE CRISIS (18 patients)
MYALGIA (18 patients)
ECZEMA (18 patients)
URINARY TRACT INFECTION (18 patients)
NEUROMYOPATHY (18 patients)
MEDICAL DEVICE COMPLICATION (18 patients)
DIVERTICULITIS (18 patients)
OSTEOMYELITIS (18 patients)
CEREBRAL ATROPHY (18 patients)
CEREBRAL VENTRICLE DILATATION (18 patients)
DIABETIC FOOT INFECTION (18 patients)
NECK PAIN (18 patients)
OLIGURIA (17 patients)
GASTROINTESTINAL DISORDER (17 patients)
HAEMATOCHEZIA (17 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (17 patients)
HYPOTHYROIDISM (17 patients)
TRANSAMINASES INCREASED (17 patients)
OROPHARYNGEAL PAIN (17 patients)
CHRONIC MYELOID LEUKAEMIA (17 patients)
NEOPLASM PROGRESSION (17 patients)
METASTASES TO ADRENALS (16 patients)
LYMPHOCYTE COUNT DECREASED (16 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (16 patients)
MULTI-ORGAN FAILURE (16 patients)
FEAR (16 patients)
PANCREATIC CARCINOMA (16 patients)
HYPERSOMNIA (16 patients)
EPILEPSY (16 patients)
SUBARACHNOID HAEMORRHAGE (16 patients)
METASTASES TO LUNG (16 patients)
TACHYCARDIA (16 patients)
MUSCULAR WEAKNESS (16 patients)
KLEBSIELLA SEPSIS (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
DYSGEUSIA (16 patients)
LUNG INFECTION (16 patients)
FAECES DISCOLOURED (16 patients)
PAIN OF SKIN (16 patients)
SPINAL FRACTURE (16 patients)
PANIC REACTION (16 patients)

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