Is ALOPECIA a side effect of SORAFENIB (RAF KINASE INHIBITOR) ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of SORAFENIB (RAF KINASE INHIBITOR) patients who developed ALOPECIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 124 individuals taking SORAFENIB (RAF KINASE INHIBITOR) reported ALOPECIA to the FDA. A total of 3329 SORAFENIB (RAF KINASE INHIBITOR) drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between SORAFENIB (RAF KINASE INHIBITOR) and ALOPECIA. In doing so, we compare SORAFENIB (RAF KINASE INHIBITOR) with other drugs that cause ALOPECIA, to help you evaluate whether or not SORAFENIB (RAF KINASE INHIBITOR) causes ALOPECIA. Likewise, this page shows the most highly-reported side effects of SORAFENIB (RAF KINASE INHIBITOR), so you can see if ALOPECIA ranks among SORAFENIB (RAF KINASE INHIBITOR)'s most well-known side effects.

Summary Statistics
Reports of SORAFENIB (RAF KINASE INHIBITOR) causing ALOPECIA: 124
Reports of any side effect of SORAFENIB (RAF KINASE INHIBITOR) : 3329
Percentage of SORAFENIB (RAF KINASE INHIBITOR) patients where ALOPECIA is a reported side effect: 3.7248%

FDA reports of any drug causing ALOPECIA : 26203
Average percentage for all medicated patients where ALOPECIA is reported as a complication: 0.1642%

Physician opinion on SORAFENIB (RAF KINASE INHIBITOR) as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing SORAFENIB (RAF KINASE INHIBITOR):

HEPATIC NEOPLASM MALIGNANT ( 770 patients )
RENAL CELL CARCINOMA ( 114 patients )
THYROID CANCER ( 65 patients )
METASTATIC RENAL CELL CARCINOMA ( 44 patients )
THYROID CANCER METASTATIC ( 35 patients )
BREAST CANCER ( 31 patients )
BREAST CANCER METASTATIC ( 27 patients )
GASTRIC CANCER ( 25 patients )
NON-SMALL CELL LUNG CANCER ( 25 patients )
COLORECTAL CANCER METASTATIC ( 22 patients )
RENAL CANCER ( 17 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 14 patients )
BILE DUCT CANCER ( 14 patients )
SALIVARY GLAND CANCER ( 7 patients )
HEPATIC CANCER METASTATIC ( 7 patients )
COLORECTAL CANCER ( 7 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 6 patients )
RECTAL CANCER ( 5 patients )
PANCREATIC CARCINOMA ( 4 patients )
PROSTATE CANCER ( 4 patients )
INTRAOCULAR MELANOMA ( 4 patients )
HEPATIC NEOPLASM MALIGNANT RECURRENT ( 3 patients )
NEOPLASM ( 3 patients )
LIVER DISORDER ( 3 patients )
ANGIOSARCOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 3 patients )
METASTASES TO LUNG ( 3 patients )
HEPATIC NEOPLASM MALIGNANT NON-RESECTABLE ( 3 patients )
COLORECTAL CANCER STAGE IV ( 3 patients )
NEOPLASM MALIGNANT ( 3 patients )
GALLBLADDER CANCER METASTATIC ( 3 patients )
BILIARY CANCER METASTATIC ( 3 patients )
METASTASIS ( 3 patients )
COLON CANCER METASTATIC ( 2 patients )
HYPOPHARYNGEAL CANCER ( 2 patients )
DESMOID TUMOUR ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
ACUTE MYELOID LEUKAEMIA (IN REMISSION) ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
OESOPHAGEAL CARCINOMA ( 2 patients )
METASTATIC MALIGNANT MELANOMA ( 2 patients )
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED ( 2 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 2 patients )
ANGINA PECTORIS ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
OSTEOSARCOMA METASTATIC ( 2 patients )
BONE SARCOMA ( 2 patients )
METASTATIC OCULAR MELANOMA ( 2 patients )
METASTATIC SALIVARY GLAND CANCER ( 2 patients )
TONSIL CANCER ( 2 patients )
MYELODYSPLASTIC SYNDROME ( 1 patients )
PROSTATE CANCER METASTATIC ( 1 patients )
GALLBLADDER CANCER ( 1 patients )
NEUROENDOCRINE TUMOUR ( 1 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 1 patients )
GLIOMA ( 1 patients )
BLADDER CANCER ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
CAROTID ARTERY DISEASE ( 1 patients )
HEPATOBLASTOMA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
ACUTE MYELOID LEUKAEMIA ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
RENAL CANCER METASTATIC ( 1 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 1 patients )
NEUROENDOCRINE CARCINOMA OF THE SKIN ( 1 patients )
MALIGNANT HISTIOCYTOSIS ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 1 patients )
SARCOMA ( 1 patients )
GERM CELL CANCER ( 1 patients )
OESOPHAGEAL ADENOCARCINOMA ( 1 patients )
SQUAMOUS CELL CARCINOMA ( 1 patients )
HEAD AND NECK CANCER ( 1 patients )
OVARIAN EPITHELIAL CANCER ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with ALOPECIA:

NEXAVAR (2114 patients)
HUMIRA (1668 patients)
FOSAMAX (1456 patients)
SYNTHROID (1366 patients)
ENBREL (1292 patients)
ASPIRIN (1181 patients)
MIRENA (1047 patients)
LIPITOR (952 patients)
REMICADE (941 patients)
ACCUTANE (842 patients)
METHOTREXATE (809 patients)
CRESTOR (789 patients)
TYSABRI (747 patients)
PREDNISONE (725 patients)
LEVOTHYROXINE SODIUM (690 patients)
PEGASYS (678 patients)
VIOXX (666 patients)
COUMADIN (646 patients)
LYRICA (633 patients)
NEXIUM (617 patients)
NEURONTIN (603 patients)
ZOMETA (589 patients)
SANDOSTATIN LAR (567 patients)
LISINOPRIL (567 patients)
RIBAVIRIN (560 patients)
FORTEO (556 patients)
FOLIC ACID (548 patients)
TOPROL-XL (528 patients)
ARIMIDEX (525 patients)
AVONEX (522 patients)
LAMICTAL (509 patients)
ATENOLOL (508 patients)
ZOLOFT (503 patients)
LEVOXYL (490 patients)
XANAX (484 patients)
SIMVASTATIN (481 patients)
VITAMIN D (477 patients)
CALCIUM (476 patients)
OMEPRAZOLE (457 patients)
PREMARIN (447 patients)
PRILOSEC (436 patients)
LASIX (436 patients)
SEROQUEL (432 patients)
HYDROCHLOROTHIAZIDE (416 patients)
NORVASC (415 patients)
PEG-INTRON (401 patients)
AREDIA (386 patients)
TOPAMAX (373 patients)
DEPAKOTE (371 patients)
PAXIL (371 patients)
COPEGUS (366 patients)
WELLBUTRIN (365 patients)
ZOCOR (364 patients)
AMBIEN (356 patients)
LEXAPRO (352 patients)
CYMBALTA (351 patients)
ACETAMINOPHEN (350 patients)
CELEBREX (346 patients)
KLONOPIN (341 patients)
METFORMIN HCL (338 patients)
VICODIN (333 patients)
ALBUTEROL (325 patients)
ATIVAN (325 patients)
FUROSEMIDE (315 patients)
BYETTA (312 patients)
SINGULAIR (311 patients)
GABAPENTIN (311 patients)
SPIRIVA (308 patients)
POTASSIUM CHLORIDE (306 patients)
CLONAZEPAM (302 patients)
ADVAIR DISKUS 100/50 (301 patients)
TAXOTERE (301 patients)
IBUPROFEN (300 patients)
PREDNISOLONE (300 patients)
LEVAQUIN (299 patients)
OXYCONTIN (299 patients)
PLAVIX (297 patients)
PROTONIX (285 patients)
FEMARA (280 patients)
PREVACID (279 patients)
PREDNISONE TAB (277 patients)
LORAZEPAM (277 patients)
EFFEXOR (274 patients)
XELODA (272 patients)
DIOVAN (264 patients)
ACTONEL (261 patients)
MULTI-VITAMIN (261 patients)
RIBASPHERE (260 patients)
WELLBUTRIN XL (252 patients)
YAZ (250 patients)
AMLODIPINE (244 patients)
DECADRON (241 patients)
ZETIA (241 patients)
REBIF (238 patients)
CYCLOPHOSPHAMIDE (235 patients)
ALPRAZOLAM (234 patients)
CHANTIX (232 patients)
PERCOCET (231 patients)
FISH OIL (228 patients)
MULTI-VITAMINS (222 patients)
DOXORUBICIN HCL (218 patients)
ZYRTEC (218 patients)
PROZAC (217 patients)
METOPROLOL TARTRATE (213 patients)
NEUPOGEN (211 patients)
COREG (209 patients)
AVASTIN (208 patients)
YASMIN (207 patients)
DEXAMETHASONE (203 patients)
ARAVA (203 patients)
FLUOROURACIL (202 patients)
ZOFRAN (201 patients)
VITAMINS (201 patients)
ASCORBIC ACID (200 patients)
ZANTAC (199 patients)
WARFARIN SODIUM (199 patients)
HERCEPTIN (198 patients)
PRADAXA (197 patients)
TEGRETOL (197 patients)
DEPAKOTE ER (196 patients)
FLEXERIL (194 patients)
BENADRYL (194 patients)
VITAMIN B-12 (193 patients)
TAMOXIFEN CITRATE (191 patients)
CARBOPLATIN (191 patients)
CELEXA (190 patients)
REBETOL (190 patients)
ALENDRONATE SODIUM (188 patients)
DEPO-PROVERA (187 patients)
NAPROXEN (184 patients)
TAXOL (183 patients)
DIAZEPAM (183 patients)
TRAZODONE HCL (182 patients)
ABILIFY (182 patients)
PREMPRO (181 patients)
ZYPREXA (181 patients)
PLAQUENIL (181 patients)
COZAAR (180 patients)
DIGOXIN (180 patients)
ALLOPURINOL (179 patients)
VITAMIN E (177 patients)
ORTHO EVRA (177 patients)
VALIUM (176 patients)
GLEEVEC (175 patients)
LANTUS (173 patients)
EPOGEN (173 patients)
BONIVA (173 patients)
PRISTIQ (172 patients)
VALTREX (172 patients)
XOLAIR (170 patients)
TRAMADOL HCL (166 patients)
KEPPRA (160 patients)
METOCLOPRAMIDE (160 patients)
ALLEGRA (159 patients)
REGLAN (158 patients)
AROMASIN (157 patients)
OXYCODONE HCL (153 patients)
ZITHROMAX (152 patients)
SORAFENIB (149 patients)
PEPCID (149 patients)
ALTACE (148 patients)
EFFEXOR XR (148 patients)
PROCRIT (147 patients)
CYTOXAN (146 patients)
RANITIDINE (146 patients)
AMOXICILLIN (145 patients)
TYLENOL (145 patients)
GILENYA (144 patients)
CLARITIN (144 patients)
DIFLUCAN (141 patients)
FASLODEX (141 patients)
CALCIUM CARBONATE (141 patients)
PACLITAXEL (140 patients)
GLUCOPHAGE (140 patients)
TASIGNA (138 patients)
DEPAKENE (138 patients)
MOTRIN (137 patients)
ELIDEL (137 patients)
NITROGLYCERIN (137 patients)
PEGINTERFERON ALFA-2A (135 patients)
HYDROCODONE (134 patients)
ONDANSETRON (133 patients)
INSULIN (133 patients)
ACTOS (133 patients)
CAPECITABINE (132 patients)
COLACE (132 patients)
LORTAB (131 patients)
AVANDIA (130 patients)
HYZAAR (130 patients)
BETASERON (130 patients)
COMPAZINE (130 patients)
THYROID TAB (129 patients)
BENICAR (128 patients)
NO CONCURRENT MEDICATION (128 patients)
DOXYCYCLINE (128 patients)
SYMBICORT (127 patients)
TRICOR (127 patients)
GEMZAR (126 patients)
FLUCONAZOLE (125 patients)
RITUXIMAB (124 patients)
ALL OTHER THERAPEUTIC PRODUCTS (124 patients)
LOPRESSOR (124 patients)
CEPHALEXIN (124 patients)
SORAFENIB (RAF KINASE INHIBITOR) (124 patients)
TYLENOL (CAPLET) (123 patients)
CLINDAMYCIN (123 patients)
HEPARIN SODIUM INJECTION (123 patients)
IFOSFAMIDE (122 patients)
CLONIDINE (121 patients)
METOPROLOL (120 patients)

Most common side effects for patients taking SORAFENIB (RAF KINASE INHIBITOR):

DIARRHOEA (613 patients)
HEPATIC FAILURE (378 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (342 patients)
HEPATIC ENCEPHALOPATHY (320 patients)
FATIGUE (300 patients)
RASH (276 patients)
ASCITES (253 patients)
ABDOMINAL PAIN (237 patients)
DECREASED APPETITE (226 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (198 patients)
PYREXIA (191 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (179 patients)
NAUSEA (165 patients)
HYPERTENSION (160 patients)
ASTHENIA (154 patients)
DEHYDRATION (140 patients)
HEPATIC FUNCTION ABNORMAL (133 patients)
DYSPNOEA (131 patients)
CONFUSIONAL STATE (131 patients)
HYPOKALAEMIA (125 patients)
ALOPECIA (124 patients)
VOMITING (118 patients)
CONSTIPATION (115 patients)
INTERSTITIAL LUNG DISEASE (114 patients)
LEFT VENTRICULAR DYSFUNCTION (113 patients)
DEATH (113 patients)
ENDOCARDITIS (112 patients)
ARTHRALGIA (111 patients)
STOMATITIS (111 patients)
ABDOMINAL PAIN UPPER (110 patients)
JAUNDICE (108 patients)
HEPATIC NEOPLASM MALIGNANT (106 patients)
GASTROINTESTINAL HAEMORRHAGE (106 patients)
RETINAL VASCULAR THROMBOSIS (103 patients)
LOWER GASTROINTESTINAL HAEMORRHAGE (103 patients)
LIVER CARCINOMA RUPTURED (101 patients)
OEDEMA PERIPHERAL (97 patients)
PLEURAL EFFUSION (97 patients)
STAPHYLOCOCCAL INFECTION (96 patients)
PNEUMONIA BACTERIAL (96 patients)
ENTEROBACTER INFECTION (96 patients)
MYOPATHY (95 patients)
DRY MOUTH (94 patients)
PAIN IN EXTREMITY (93 patients)
ANXIETY (90 patients)
MALAISE (89 patients)
PULMONARY EMBOLISM (85 patients)
ANAEMIA (84 patients)
PLATELET COUNT DECREASED (81 patients)
BACK PAIN (79 patients)
SEPSIS (78 patients)
PRURITUS (78 patients)
DUODENAL ULCER (77 patients)
MIGRAINE (76 patients)
MITRAL VALVE INCOMPETENCE (76 patients)
HYPOGLYCAEMIA (76 patients)
C-REACTIVE PROTEIN INCREASED (74 patients)
BLOOD PRESSURE INCREASED (73 patients)
VARICES OESOPHAGEAL (73 patients)
HEADACHE (72 patients)
RETINAL VEIN OCCLUSION (72 patients)
ABASIA (69 patients)
RENAL FAILURE ACUTE (69 patients)
WEIGHT DECREASED (67 patients)
DEEP VEIN THROMBOSIS (67 patients)
DIZZINESS (65 patients)
ERYTHEMA (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (64 patients)
CONVULSION (63 patients)
ALANINE AMINOTRANSFERASE INCREASED (62 patients)
DYSPHONIA (62 patients)
CEREBRAL HAEMORRHAGE (60 patients)
APHAGIA (58 patients)
COLITIS (58 patients)
PNEUMONIA (57 patients)
GASTRIC ULCER (56 patients)
HYPONATRAEMIA (55 patients)
HAEMOGLOBIN DECREASED (53 patients)
RESPIRATORY FAILURE (52 patients)
LUNG DISORDER (52 patients)
CEREBRAL ISCHAEMIA (49 patients)
PARAESTHESIA (49 patients)
BLOOD BILIRUBIN INCREASED (48 patients)
GAIT DISTURBANCE (48 patients)
THYROID CANCER METASTATIC (44 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (43 patients)
PERICARDIAL EFFUSION (41 patients)
THROMBOCYTOPENIA (41 patients)
BLISTER (41 patients)
FEBRILE NEUTROPENIA (40 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (40 patients)
HALLUCINATION (40 patients)
CHILLS (40 patients)
AMMONIA INCREASED (39 patients)
SKIN ULCER (39 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (38 patients)
PAIN (38 patients)
HYPOALBUMINAEMIA (38 patients)
HYPOCALCAEMIA (37 patients)
FALL (37 patients)
POLLAKIURIA (37 patients)
BLOOD PRESSURE DECREASED (37 patients)
SKIN EXFOLIATION (37 patients)
INSOMNIA (36 patients)
CARDIAC ARREST (36 patients)
HYPOAESTHESIA (35 patients)
INFECTIOUS PERITONITIS (35 patients)
MYOCARDIAL INFARCTION (35 patients)
RETINAL VASCULAR DISORDER (34 patients)
RENAL FAILURE (34 patients)
LIPASE INCREASED (34 patients)
HYPERKALAEMIA (33 patients)
HYPERGLYCAEMIA (33 patients)
HAEMOPTYSIS (31 patients)
ATRIAL FIBRILLATION (30 patients)
GENERALISED OEDEMA (30 patients)
FAECAL INCONTINENCE (30 patients)
WHITE BLOOD CELL COUNT DECREASED (30 patients)
CELLULITIS (29 patients)
CHEST PAIN (29 patients)
SOMNOLENCE (29 patients)
HYPERBILIRUBINAEMIA (28 patients)
HYPOTENSION (28 patients)
MUSCLE SPASMS (28 patients)
ABDOMINAL DISTENSION (27 patients)
WHITE BLOOD CELL COUNT INCREASED (27 patients)
VISION BLURRED (27 patients)
HEPATIC PAIN (26 patients)
BLOOD ALBUMIN DECREASED (26 patients)
DYSURIA (25 patients)
RASH GENERALISED (25 patients)
BLOOD SODIUM DECREASED (25 patients)
BLOOD URIC ACID INCREASED (25 patients)
COMA (25 patients)
COUGH (25 patients)
PANCYTOPENIA (25 patients)
ACUTE ABDOMEN (24 patients)
EOSINOPHIL COUNT INCREASED (24 patients)
CEREBROVASCULAR ACCIDENT (24 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (23 patients)
CEREBRAL INFARCTION (23 patients)
HYPOMAGNESAEMIA (23 patients)
RETINAL VEIN THROMBOSIS (23 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (23 patients)
TUMOUR LYSIS SYNDROME (22 patients)
HYPOPHOSPHATAEMIA (22 patients)
INFECTION (22 patients)
ORAL PAIN (22 patients)
BLOOD CREATININE INCREASED (22 patients)
NEUTROPENIA (22 patients)
RENAL IMPAIRMENT (22 patients)
LETHARGY (22 patients)
SKIN TOXICITY (21 patients)
TONGUE BLISTERING (21 patients)
LIVER ABSCESS (21 patients)
HAEMATEMESIS (21 patients)
OESOPHAGEAL VARICES HAEMORRHAGE (20 patients)
MENTAL IMPAIRMENT (20 patients)
NERVOUSNESS (20 patients)
NEPHROTIC SYNDROME (20 patients)
HYPOPHAGIA (20 patients)
ADRENAL INSUFFICIENCY (19 patients)
DRY SKIN (19 patients)
BLOOD AMYLASE INCREASED (19 patients)
OEDEMA (19 patients)
INFECTIOUS PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
COMA HEPATIC (19 patients)
HEART RATE INCREASED (18 patients)
HYPERTENSIVE CRISIS (18 patients)
MYALGIA (18 patients)
ECZEMA (18 patients)
URINARY TRACT INFECTION (18 patients)
NEUROMYOPATHY (18 patients)
MEDICAL DEVICE COMPLICATION (18 patients)
DIVERTICULITIS (18 patients)
OSTEOMYELITIS (18 patients)
CEREBRAL ATROPHY (18 patients)
CEREBRAL VENTRICLE DILATATION (18 patients)
DIABETIC FOOT INFECTION (18 patients)
NECK PAIN (18 patients)
OLIGURIA (17 patients)
GASTROINTESTINAL DISORDER (17 patients)
HAEMATOCHEZIA (17 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (17 patients)
HYPOTHYROIDISM (17 patients)
TRANSAMINASES INCREASED (17 patients)
OROPHARYNGEAL PAIN (17 patients)
CHRONIC MYELOID LEUKAEMIA (17 patients)
NEOPLASM PROGRESSION (17 patients)
METASTASES TO ADRENALS (16 patients)
LYMPHOCYTE COUNT DECREASED (16 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (16 patients)
MULTI-ORGAN FAILURE (16 patients)
FEAR (16 patients)
PANCREATIC CARCINOMA (16 patients)
HYPERSOMNIA (16 patients)
EPILEPSY (16 patients)
SUBARACHNOID HAEMORRHAGE (16 patients)
METASTASES TO LUNG (16 patients)
TACHYCARDIA (16 patients)
MUSCULAR WEAKNESS (16 patients)
KLEBSIELLA SEPSIS (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
DYSGEUSIA (16 patients)
LUNG INFECTION (16 patients)
FAECES DISCOLOURED (16 patients)
PAIN OF SKIN (16 patients)
SPINAL FRACTURE (16 patients)
PANIC REACTION (16 patients)

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