Study of possible correlation between BLOOD PRESSURE DECREASED and SORAFENIB (RAF KINASE INHIBITOR)
Accompanying discussion about FactMed users Questions and Concerns
About this FactMed analysis covering adverse side effect reports of SORAFENIB (RAF KINASE INHIBITOR) patients who developed BLOOD PRESSURE DECREASED.
FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 37 individuals taking SORAFENIB (RAF KINASE INHIBITOR) reported BLOOD PRESSURE DECREASED to the FDA. A total of 3329 SORAFENIB (RAF KINASE INHIBITOR) drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.FDA Research Report
Introduction This page is designed to help you determine the relationship, if any, between SORAFENIB (RAF KINASE INHIBITOR) and BLOOD PRESSURE DECREASED. In doing so, we compare SORAFENIB (RAF KINASE INHIBITOR) with other drugs that cause BLOOD PRESSURE DECREASED, to help you evaluate whether or not SORAFENIB (RAF KINASE INHIBITOR) causes BLOOD PRESSURE DECREASED. Likewise, this page shows the most highly-reported side effects of SORAFENIB (RAF KINASE INHIBITOR), so you can see if BLOOD PRESSURE DECREASED ranks among SORAFENIB (RAF KINASE INHIBITOR)'s most well-known side effects.
Summary StatisticsReports of SORAFENIB (RAF KINASE INHIBITOR) causing BLOOD PRESSURE DECREASED: 37
Reports of any side effect of SORAFENIB (RAF KINASE INHIBITOR) : 3329
Percentage of SORAFENIB (RAF KINASE INHIBITOR) patients where BLOOD PRESSURE DECREASED is a reported side effect: 1.1114%
FDA reports of any drug causing BLOOD PRESSURE DECREASED : 23294
Average percentage for all medicated patients where BLOOD PRESSURE DECREASED is reported as a complication: 0.1460%
Physician opinion on SORAFENIB (RAF KINASE INHIBITOR) as adverse event culprit:
Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing SORAFENIB (RAF KINASE INHIBITOR):
HEPATIC NEOPLASM MALIGNANT
( 770 patients )RENAL CELL CARCINOMA ( 114 patients )
THYROID CANCER ( 65 patients )
METASTATIC RENAL CELL CARCINOMA ( 44 patients )
THYROID CANCER METASTATIC ( 35 patients )
BREAST CANCER ( 31 patients )
BREAST CANCER METASTATIC ( 27 patients )
GASTRIC CANCER ( 25 patients )
NON-SMALL CELL LUNG CANCER ( 25 patients )
COLORECTAL CANCER METASTATIC ( 22 patients )
RENAL CANCER ( 17 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 14 patients )
BILE DUCT CANCER ( 14 patients )
SALIVARY GLAND CANCER ( 7 patients )
HEPATIC CANCER METASTATIC ( 7 patients )
COLORECTAL CANCER ( 7 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 6 patients )
RECTAL CANCER ( 5 patients )
PANCREATIC CARCINOMA ( 4 patients )
PROSTATE CANCER ( 4 patients )
INTRAOCULAR MELANOMA ( 4 patients )
HEPATIC NEOPLASM MALIGNANT RECURRENT ( 3 patients )
NEOPLASM ( 3 patients )
LIVER DISORDER ( 3 patients )
ANGIOSARCOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 3 patients )
METASTASES TO LUNG ( 3 patients )
HEPATIC NEOPLASM MALIGNANT NON-RESECTABLE ( 3 patients )
COLORECTAL CANCER STAGE IV ( 3 patients )
NEOPLASM MALIGNANT ( 3 patients )
GALLBLADDER CANCER METASTATIC ( 3 patients )
BILIARY CANCER METASTATIC ( 3 patients )
METASTASIS ( 3 patients )
COLON CANCER METASTATIC ( 2 patients )
HYPOPHARYNGEAL CANCER ( 2 patients )
DESMOID TUMOUR ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
ACUTE MYELOID LEUKAEMIA (IN REMISSION) ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
OESOPHAGEAL CARCINOMA ( 2 patients )
METASTATIC MALIGNANT MELANOMA ( 2 patients )
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED ( 2 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 2 patients )
ANGINA PECTORIS ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
OSTEOSARCOMA METASTATIC ( 2 patients )
BONE SARCOMA ( 2 patients )
METASTATIC OCULAR MELANOMA ( 2 patients )
METASTATIC SALIVARY GLAND CANCER ( 2 patients )
TONSIL CANCER ( 2 patients )
MYELODYSPLASTIC SYNDROME ( 1 patients )
PROSTATE CANCER METASTATIC ( 1 patients )
GALLBLADDER CANCER ( 1 patients )
NEUROENDOCRINE TUMOUR ( 1 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 1 patients )
GLIOMA ( 1 patients )
BLADDER CANCER ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
CAROTID ARTERY DISEASE ( 1 patients )
HEPATOBLASTOMA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
ACUTE MYELOID LEUKAEMIA ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
RENAL CANCER METASTATIC ( 1 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 1 patients )
NEUROENDOCRINE CARCINOMA OF THE SKIN ( 1 patients )
MALIGNANT HISTIOCYTOSIS ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 1 patients )
SARCOMA ( 1 patients )
GERM CELL CANCER ( 1 patients )
OESOPHAGEAL ADENOCARCINOMA ( 1 patients )
SQUAMOUS CELL CARCINOMA ( 1 patients )
HEAD AND NECK CANCER ( 1 patients )
OVARIAN EPITHELIAL CANCER ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with BLOOD PRESSURE DECREASED:
HEPARIN SODIUM INJECTION (2386 patients)
ASPIRIN (2038 patients)
REMICADE (1308 patients)
LASIX (1078 patients)
LISINOPRIL (879 patients)
FORTEO (821 patients)
DIOVAN (815 patients)
HEPARIN SODIUM (807 patients)
LIPITOR (787 patients)
FUROSEMIDE (784 patients)
NORVASC (651 patients)
DIGOXIN (639 patients)
SANDOSTATIN LAR (633 patients)
ATENOLOL (625 patients)
PLAVIX (597 patients)
PREDNISOLONE (595 patients)
SYNTHROID (538 patients)
OMEPRAZOLE (533 patients)
XOLAIR (526 patients)
SIMVASTATIN (513 patients)
WARFARIN SODIUM (504 patients)
COUMADIN (494 patients)
ACETAMINOPHEN (490 patients)
VIOXX (487 patients)
HYDROCHLOROTHIAZIDE (484 patients)
SEROQUEL (484 patients)
PREDNISONE (469 patients)
ALLOPURINOL (468 patients)
METHOTREXATE (425 patients)
TOPROL-XL (420 patients)
NEXIUM (414 patients)
FOLIC ACID (412 patients)
METFORMIN HCL (398 patients)
HEPARIN SODIUM 5,000 UNITS IN DEXTROSE 5% (398 patients)
FOSAMAX (397 patients)
LEVOTHYROXINE SODIUM (397 patients)
GILENYA (394 patients)
LYRICA (393 patients)
HEPARIN (376 patients)
COREG (375 patients)
METOPROLOL TARTRATE (369 patients)
AMLODIPINE (355 patients)
VOLTAREN (353 patients)
AVONEX (351 patients)
FENTANYL (348 patients)
POTASSIUM CHLORIDE (339 patients)
LANSOPRAZOLE (328 patients)
CARVEDILOL (328 patients)
BYETTA (326 patients)
XANAX (326 patients)
HUMIRA (322 patients)
VITAMIN D (322 patients)
TYSABRI (320 patients)
BENADRYL (316 patients)
ZOLOFT (313 patients)
NEURONTIN (312 patients)
PROPOFOL (309 patients)
CYMBALTA (304 patients)
ENALAPRIL MALEATE (299 patients)
PROTONIX (294 patients)
DECADRON (294 patients)
SPIRONOLACTONE (292 patients)
ZOMETA (291 patients)
PRILOSEC (291 patients)
ALBUTEROL (285 patients)
INSULIN (284 patients)
GABAPENTIN (280 patients)
CRESTOR (279 patients)
CLONAZEPAM (279 patients)
FAMOTIDINE (277 patients)
PAXIL (277 patients)
ZOCOR (275 patients)
AVELOX (274 patients)
ZANTAC (274 patients)
LORAZEPAM (269 patients)
AMBIEN (266 patients)
IBUPROFEN (266 patients)
MORPHINE (266 patients)
FLOMAX (260 patients)
CELEBREX (258 patients)
COZAAR (253 patients)
ALDACTONE (251 patients)
PREVACID (250 patients)
NITROGLYCERIN (248 patients)
DEXAMETHASONE (245 patients)
CLONIDINE (243 patients)
PREDONINE (239 patients)
DIOVAN HCT (238 patients)
LANTUS (237 patients)
LEXAPRO (235 patients)
SOLU-MEDROL (230 patients)
RAMIPRIL (226 patients)
CISPLATIN (225 patients)
ATIVAN (224 patients)
METOPROLOL (223 patients)
LEVAQUIN (218 patients)
PREDNISONE TAB (217 patients)
SINGULAIR (216 patients)
FLUOROURACIL (216 patients)
DIAZEPAM (215 patients)
OXYCONTIN (214 patients)
CALCIUM (212 patients)
ZYPREXA (211 patients)
SPIRIVA (211 patients)
NIASPAN (209 patients)
TEGRETOL (207 patients)
CHANTIX (206 patients)
MAGNESIUM OXIDE (206 patients)
CARBOPLATIN (205 patients)
ZOFRAN (203 patients)
VICODIN (202 patients)
RISPERDAL (202 patients)
NEORAL (201 patients)
PERCOCET (200 patients)
ARICEPT (197 patients)
OXYGEN (195 patients)
KLONOPIN (193 patients)
LOPRESSOR (190 patients)
ACTOS (187 patients)
LOXONIN (187 patients)
RHEUMATREX (186 patients)
ALPRAZOLAM (186 patients)
MULTI-VITAMINS (185 patients)
CLOZARIL (184 patients)
CYCLOPHOSPHAMIDE (182 patients)
RANITIDINE (178 patients)
TYLENOL (175 patients)
MUCOSTA (175 patients)
LOVENOX (175 patients)
ADVAIR DISKUS 100/50 (173 patients)
VANCOMYCIN (171 patients)
ENBREL (170 patients)
PANTOPRAZOLE (170 patients)
BENICAR (169 patients)
DIPRIVAN (169 patients)
AMLODIPINE BESYLATE (168 patients)
ALTACE (168 patients)
MICARDIS (168 patients)
VIAGRA (168 patients)
VALIUM (167 patients)
NIFEDIPINE (166 patients)
VERAPAMIL (165 patients)
RENAGEL (162 patients)
AMARYL (159 patients)
SEVOFLURANE (158 patients)
TYLENOL (CAPLET) (155 patients)
VITAMIN B-12 (155 patients)
MULTI-VITAMIN (155 patients)
BACLOFEN (154 patients)
TAXOTERE (154 patients)
EFFEXOR (152 patients)
ALLEGRA (152 patients)
BACTRIM (151 patients)
IRON (151 patients)
ZYRTEC (150 patients)
DIANEAL (150 patients)
MIDAZOLAM HCL (150 patients)
METOPROLOL SUCCINATE (145 patients)
ATACAND (144 patients)
ASCORBIC ACID (144 patients)
ACTONEL (144 patients)
CITALOPRAM HYDROBROMIDE (144 patients)
PREMARIN (143 patients)
CALCIUM CARBONATE (142 patients)
TRACLEER (142 patients)
LEVOFLOXACIN (142 patients)
EXJADE (141 patients)
HEPARIN SODIUM 1,000 UNITS AND SODIUM CHLORIDE 0.9% (140 patients)
WARFARIN (140 patients)
ERBITUX (139 patients)
GLEEVEC (138 patients)
BETASERON (137 patients)
MORPHINE SULFATE (137 patients)
ZETIA (136 patients)
AMIODARONE HCL (136 patients)
PROZAC (136 patients)
ISOSORBIDE MONONITRATE (136 patients)
LIDOCAINE (135 patients)
FISH OIL (135 patients)
DILTIAZEM (134 patients)
ACETYLSALICYLIC ACID SRT (134 patients)
DIFLUCAN (133 patients)
EXELON (132 patients)
AMOXICILLIN (131 patients)
BISOPROLOL FUMARATE (131 patients)
DOPAMINE HCL (130 patients)
HUMULIN R (130 patients)
REBIF (129 patients)
PRADAXA (129 patients)
PEG-INTRON (129 patients)
LORTAB (129 patients)
NEXAVAR (127 patients)
LOSARTAN POTASSIUM (126 patients)
SYMBICORT (125 patients)
TRAMADOL HCL (124 patients)
PACLITAXEL (124 patients)
DEPAKENE (124 patients)
TAXOL (122 patients)
REGLAN (122 patients)
TRAZODONE HCL (122 patients)
EXFORGE (122 patients)
OXYCODONE HCL (122 patients)
REVLIMID (122 patients)
EPOGEN (122 patients)
OLMESARTAN MEDOXOMIL (122 patients)
AMITRIPTYLINE HCL (121 patients)
TORSEMIDE (121 patients)
VECURONIUM BROMIDE (120 patients)
BLOPRESS (118 patients)
TAKEPRON (117 patients)
Most common side effects for patients taking SORAFENIB (RAF KINASE INHIBITOR):
DIARRHOEA (613 patients) HEPATIC FAILURE (378 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (342 patients)
HEPATIC ENCEPHALOPATHY (320 patients)
FATIGUE (300 patients)
RASH (276 patients)
ASCITES (253 patients)
ABDOMINAL PAIN (237 patients)
DECREASED APPETITE (226 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (198 patients)
PYREXIA (191 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (179 patients)
NAUSEA (165 patients)
HYPERTENSION (160 patients)
ASTHENIA (154 patients)
DEHYDRATION (140 patients)
HEPATIC FUNCTION ABNORMAL (133 patients)
DYSPNOEA (131 patients)
CONFUSIONAL STATE (131 patients)
HYPOKALAEMIA (125 patients)
ALOPECIA (124 patients)
VOMITING (118 patients)
CONSTIPATION (115 patients)
INTERSTITIAL LUNG DISEASE (114 patients)
LEFT VENTRICULAR DYSFUNCTION (113 patients)
DEATH (113 patients)
ENDOCARDITIS (112 patients)
ARTHRALGIA (111 patients)
STOMATITIS (111 patients)
ABDOMINAL PAIN UPPER (110 patients)
JAUNDICE (108 patients)
HEPATIC NEOPLASM MALIGNANT (106 patients)
GASTROINTESTINAL HAEMORRHAGE (106 patients)
RETINAL VASCULAR THROMBOSIS (103 patients)
LOWER GASTROINTESTINAL HAEMORRHAGE (103 patients)
LIVER CARCINOMA RUPTURED (101 patients)
OEDEMA PERIPHERAL (97 patients)
PLEURAL EFFUSION (97 patients)
STAPHYLOCOCCAL INFECTION (96 patients)
PNEUMONIA BACTERIAL (96 patients)
ENTEROBACTER INFECTION (96 patients)
MYOPATHY (95 patients)
DRY MOUTH (94 patients)
PAIN IN EXTREMITY (93 patients)
ANXIETY (90 patients)
MALAISE (89 patients)
PULMONARY EMBOLISM (85 patients)
ANAEMIA (84 patients)
PLATELET COUNT DECREASED (81 patients)
BACK PAIN (79 patients)
SEPSIS (78 patients)
PRURITUS (78 patients)
DUODENAL ULCER (77 patients)
MIGRAINE (76 patients)
MITRAL VALVE INCOMPETENCE (76 patients)
HYPOGLYCAEMIA (76 patients)
C-REACTIVE PROTEIN INCREASED (74 patients)
BLOOD PRESSURE INCREASED (73 patients)
VARICES OESOPHAGEAL (73 patients)
HEADACHE (72 patients)
RETINAL VEIN OCCLUSION (72 patients)
ABASIA (69 patients)
RENAL FAILURE ACUTE (69 patients)
WEIGHT DECREASED (67 patients)
DEEP VEIN THROMBOSIS (67 patients)
DIZZINESS (65 patients)
ERYTHEMA (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (64 patients)
CONVULSION (63 patients)
ALANINE AMINOTRANSFERASE INCREASED (62 patients)
DYSPHONIA (62 patients)
CEREBRAL HAEMORRHAGE (60 patients)
APHAGIA (58 patients)
COLITIS (58 patients)
PNEUMONIA (57 patients)
GASTRIC ULCER (56 patients)
HYPONATRAEMIA (55 patients)
HAEMOGLOBIN DECREASED (53 patients)
RESPIRATORY FAILURE (52 patients)
LUNG DISORDER (52 patients)
CEREBRAL ISCHAEMIA (49 patients)
PARAESTHESIA (49 patients)
BLOOD BILIRUBIN INCREASED (48 patients)
GAIT DISTURBANCE (48 patients)
THYROID CANCER METASTATIC (44 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (43 patients)
PERICARDIAL EFFUSION (41 patients)
THROMBOCYTOPENIA (41 patients)
BLISTER (41 patients)
FEBRILE NEUTROPENIA (40 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (40 patients)
HALLUCINATION (40 patients)
CHILLS (40 patients)
AMMONIA INCREASED (39 patients)
SKIN ULCER (39 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (38 patients)
PAIN (38 patients)
HYPOALBUMINAEMIA (38 patients)
HYPOCALCAEMIA (37 patients)
FALL (37 patients)
POLLAKIURIA (37 patients)
BLOOD PRESSURE DECREASED (37 patients)
SKIN EXFOLIATION (37 patients)
INSOMNIA (36 patients)
CARDIAC ARREST (36 patients)
HYPOAESTHESIA (35 patients)
INFECTIOUS PERITONITIS (35 patients)
MYOCARDIAL INFARCTION (35 patients)
RETINAL VASCULAR DISORDER (34 patients)
RENAL FAILURE (34 patients)
LIPASE INCREASED (34 patients)
HYPERKALAEMIA (33 patients)
HYPERGLYCAEMIA (33 patients)
HAEMOPTYSIS (31 patients)
ATRIAL FIBRILLATION (30 patients)
GENERALISED OEDEMA (30 patients)
FAECAL INCONTINENCE (30 patients)
WHITE BLOOD CELL COUNT DECREASED (30 patients)
CELLULITIS (29 patients)
CHEST PAIN (29 patients)
SOMNOLENCE (29 patients)
HYPERBILIRUBINAEMIA (28 patients)
HYPOTENSION (28 patients)
MUSCLE SPASMS (28 patients)
ABDOMINAL DISTENSION (27 patients)
WHITE BLOOD CELL COUNT INCREASED (27 patients)
VISION BLURRED (27 patients)
HEPATIC PAIN (26 patients)
BLOOD ALBUMIN DECREASED (26 patients)
DYSURIA (25 patients)
RASH GENERALISED (25 patients)
BLOOD SODIUM DECREASED (25 patients)
BLOOD URIC ACID INCREASED (25 patients)
COMA (25 patients)
COUGH (25 patients)
PANCYTOPENIA (25 patients)
ACUTE ABDOMEN (24 patients)
EOSINOPHIL COUNT INCREASED (24 patients)
CEREBROVASCULAR ACCIDENT (24 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (23 patients)
CEREBRAL INFARCTION (23 patients)
HYPOMAGNESAEMIA (23 patients)
RETINAL VEIN THROMBOSIS (23 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (23 patients)
TUMOUR LYSIS SYNDROME (22 patients)
HYPOPHOSPHATAEMIA (22 patients)
INFECTION (22 patients)
ORAL PAIN (22 patients)
BLOOD CREATININE INCREASED (22 patients)
NEUTROPENIA (22 patients)
RENAL IMPAIRMENT (22 patients)
LETHARGY (22 patients)
SKIN TOXICITY (21 patients)
TONGUE BLISTERING (21 patients)
LIVER ABSCESS (21 patients)
HAEMATEMESIS (21 patients)
OESOPHAGEAL VARICES HAEMORRHAGE (20 patients)
MENTAL IMPAIRMENT (20 patients)
NERVOUSNESS (20 patients)
NEPHROTIC SYNDROME (20 patients)
HYPOPHAGIA (20 patients)
ADRENAL INSUFFICIENCY (19 patients)
DRY SKIN (19 patients)
BLOOD AMYLASE INCREASED (19 patients)
OEDEMA (19 patients)
INFECTIOUS PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
COMA HEPATIC (19 patients)
HEART RATE INCREASED (18 patients)
HYPERTENSIVE CRISIS (18 patients)
MYALGIA (18 patients)
ECZEMA (18 patients)
URINARY TRACT INFECTION (18 patients)
NEUROMYOPATHY (18 patients)
MEDICAL DEVICE COMPLICATION (18 patients)
DIVERTICULITIS (18 patients)
OSTEOMYELITIS (18 patients)
CEREBRAL ATROPHY (18 patients)
CEREBRAL VENTRICLE DILATATION (18 patients)
DIABETIC FOOT INFECTION (18 patients)
NECK PAIN (18 patients)
OLIGURIA (17 patients)
GASTROINTESTINAL DISORDER (17 patients)
HAEMATOCHEZIA (17 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (17 patients)
HYPOTHYROIDISM (17 patients)
TRANSAMINASES INCREASED (17 patients)
OROPHARYNGEAL PAIN (17 patients)
CHRONIC MYELOID LEUKAEMIA (17 patients)
NEOPLASM PROGRESSION (17 patients)
METASTASES TO ADRENALS (16 patients)
LYMPHOCYTE COUNT DECREASED (16 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (16 patients)
MULTI-ORGAN FAILURE (16 patients)
FEAR (16 patients)
PANCREATIC CARCINOMA (16 patients)
HYPERSOMNIA (16 patients)
EPILEPSY (16 patients)
SUBARACHNOID HAEMORRHAGE (16 patients)
METASTASES TO LUNG (16 patients)
TACHYCARDIA (16 patients)
MUSCULAR WEAKNESS (16 patients)
KLEBSIELLA SEPSIS (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
DYSGEUSIA (16 patients)
LUNG INFECTION (16 patients)
FAECES DISCOLOURED (16 patients)
PAIN OF SKIN (16 patients)
SPINAL FRACTURE (16 patients)
PANIC REACTION (16 patients)
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Recent FactMed Activity for SORAFENIB (RAF KINASE INHIBITOR)
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