Study of possible correlation between DYSPEPSIA and SORAFENIB (RAF KINASE INHIBITOR)
Accompanying discussion about FactMed users Questions and Concerns
About this FactMed analysis covering adverse side effect reports of SORAFENIB (RAF KINASE INHIBITOR) patients who developed DYSPEPSIA.
FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 19 individuals taking SORAFENIB (RAF KINASE INHIBITOR) reported DYSPEPSIA to the FDA. A total of 3329 SORAFENIB (RAF KINASE INHIBITOR) drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.FDA Research Report
Introduction This page is designed to help you determine the relationship, if any, between SORAFENIB (RAF KINASE INHIBITOR) and DYSPEPSIA. In doing so, we compare SORAFENIB (RAF KINASE INHIBITOR) with other drugs that cause DYSPEPSIA, to help you evaluate whether or not SORAFENIB (RAF KINASE INHIBITOR) causes DYSPEPSIA. Likewise, this page shows the most highly-reported side effects of SORAFENIB (RAF KINASE INHIBITOR), so you can see if DYSPEPSIA ranks among SORAFENIB (RAF KINASE INHIBITOR)'s most well-known side effects.
Summary StatisticsReports of SORAFENIB (RAF KINASE INHIBITOR) causing DYSPEPSIA: 19
Reports of any side effect of SORAFENIB (RAF KINASE INHIBITOR) : 3329
Percentage of SORAFENIB (RAF KINASE INHIBITOR) patients where DYSPEPSIA is a reported side effect: 0.5707%
FDA reports of any drug causing DYSPEPSIA : 27791
Average percentage for all medicated patients where DYSPEPSIA is reported as a complication: 0.1742%
Physician opinion on SORAFENIB (RAF KINASE INHIBITOR) as adverse event culprit:
Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing SORAFENIB (RAF KINASE INHIBITOR):
HEPATIC NEOPLASM MALIGNANT
( 770 patients )RENAL CELL CARCINOMA ( 114 patients )
THYROID CANCER ( 65 patients )
METASTATIC RENAL CELL CARCINOMA ( 44 patients )
THYROID CANCER METASTATIC ( 35 patients )
BREAST CANCER ( 31 patients )
BREAST CANCER METASTATIC ( 27 patients )
GASTRIC CANCER ( 25 patients )
NON-SMALL CELL LUNG CANCER ( 25 patients )
COLORECTAL CANCER METASTATIC ( 22 patients )
RENAL CANCER ( 17 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 14 patients )
BILE DUCT CANCER ( 14 patients )
SALIVARY GLAND CANCER ( 7 patients )
HEPATIC CANCER METASTATIC ( 7 patients )
COLORECTAL CANCER ( 7 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 6 patients )
RECTAL CANCER ( 5 patients )
PANCREATIC CARCINOMA ( 4 patients )
PROSTATE CANCER ( 4 patients )
INTRAOCULAR MELANOMA ( 4 patients )
HEPATIC NEOPLASM MALIGNANT RECURRENT ( 3 patients )
NEOPLASM ( 3 patients )
LIVER DISORDER ( 3 patients )
ANGIOSARCOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 3 patients )
METASTASES TO LUNG ( 3 patients )
HEPATIC NEOPLASM MALIGNANT NON-RESECTABLE ( 3 patients )
COLORECTAL CANCER STAGE IV ( 3 patients )
NEOPLASM MALIGNANT ( 3 patients )
GALLBLADDER CANCER METASTATIC ( 3 patients )
BILIARY CANCER METASTATIC ( 3 patients )
METASTASIS ( 3 patients )
COLON CANCER METASTATIC ( 2 patients )
HYPOPHARYNGEAL CANCER ( 2 patients )
DESMOID TUMOUR ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
ACUTE MYELOID LEUKAEMIA (IN REMISSION) ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
OESOPHAGEAL CARCINOMA ( 2 patients )
METASTATIC MALIGNANT MELANOMA ( 2 patients )
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED ( 2 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 2 patients )
ANGINA PECTORIS ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
OSTEOSARCOMA METASTATIC ( 2 patients )
BONE SARCOMA ( 2 patients )
METASTATIC OCULAR MELANOMA ( 2 patients )
METASTATIC SALIVARY GLAND CANCER ( 2 patients )
TONSIL CANCER ( 2 patients )
MYELODYSPLASTIC SYNDROME ( 1 patients )
PROSTATE CANCER METASTATIC ( 1 patients )
GALLBLADDER CANCER ( 1 patients )
NEUROENDOCRINE TUMOUR ( 1 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 1 patients )
GLIOMA ( 1 patients )
BLADDER CANCER ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
CAROTID ARTERY DISEASE ( 1 patients )
HEPATOBLASTOMA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
ACUTE MYELOID LEUKAEMIA ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
RENAL CANCER METASTATIC ( 1 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 1 patients )
NEUROENDOCRINE CARCINOMA OF THE SKIN ( 1 patients )
MALIGNANT HISTIOCYTOSIS ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 1 patients )
SARCOMA ( 1 patients )
GERM CELL CANCER ( 1 patients )
OESOPHAGEAL ADENOCARCINOMA ( 1 patients )
SQUAMOUS CELL CARCINOMA ( 1 patients )
HEAD AND NECK CANCER ( 1 patients )
OVARIAN EPITHELIAL CANCER ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with DYSPEPSIA:
NEXIUM (4341 patients)
VIOXX (4237 patients)
FOSAMAX (3527 patients)
ASPIRIN (2618 patients)
BYETTA (1689 patients)
PRADAXA (1479 patients)
LIPITOR (1327 patients)
PRILOSEC (1314 patients)
SYNTHROID (1125 patients)
YAZ (1072 patients)
OMEPRAZOLE (1041 patients)
YASMIN (981 patients)
LISINOPRIL (907 patients)
ACCUTANE (877 patients)
ZOLOFT (857 patients)
PREDNISONE (853 patients)
CELEBREX (831 patients)
PROTONIX (821 patients)
SEROQUEL (809 patients)
PREVACID (797 patients)
XANAX (787 patients)
ATENOLOL (787 patients)
ZOMETA (781 patients)
CHANTIX (756 patients)
IBUPROFEN (754 patients)
METFORMIN HCL (753 patients)
LASIX (739 patients)
NEURONTIN (720 patients)
NORVASC (715 patients)
AMBIEN (712 patients)
BONIVA (697 patients)
PLAVIX (696 patients)
SIMVASTATIN (686 patients)
ZOCOR (683 patients)
CRESTOR (675 patients)
HYDROCHLOROTHIAZIDE (641 patients)
ZANTAC (635 patients)
PAXIL (633 patients)
COUMADIN (624 patients)
TOPROL-XL (622 patients)
ALBUTEROL (610 patients)
FORTEO (610 patients)
AREDIA (592 patients)
OXYCONTIN (580 patients)
FUROSEMIDE (549 patients)
VITAMIN D (542 patients)
DIOVAN (517 patients)
LEXAPRO (515 patients)
PREMARIN (514 patients)
HUMIRA (512 patients)
ACETAMINOPHEN (511 patients)
GLUCOPHAGE (510 patients)
FOLIC ACID (507 patients)
VICODIN (496 patients)
LANTUS (489 patients)
NIASPAN (481 patients)
CYMBALTA (465 patients)
LEVOTHYROXINE SODIUM (459 patients)
ATIVAN (456 patients)
METHOTREXATE (449 patients)
DIGOXIN (443 patients)
LYRICA (443 patients)
PERCOCET (436 patients)
SINGULAIR (419 patients)
LORAZEPAM (415 patients)
ADVAIR DISKUS 100/50 (412 patients)
CALCIUM (409 patients)
ENBREL (400 patients)
PROZAC (397 patients)
LEVAQUIN (395 patients)
ACTONEL (382 patients)
LORTAB (377 patients)
VITAMIN E (373 patients)
GABAPENTIN (366 patients)
ASCORBIC ACID (362 patients)
MULTI-VITAMIN (355 patients)
FISH OIL (355 patients)
ZYRTEC (354 patients)
SPIRIVA (352 patients)
ACIPHEX (345 patients)
ALPRAZOLAM (337 patients)
ACTOS (336 patients)
POTASSIUM CHLORIDE (334 patients)
AMOXICILLIN (332 patients)
KLONOPIN (332 patients)
METOPROLOL TARTRATE (332 patients)
WELLBUTRIN (331 patients)
LEVOXYL (331 patients)
TYLENOL (328 patients)
CALCIUM CARBONATE (328 patients)
EFFEXOR (325 patients)
ALLOPURINOL (323 patients)
FOSAMAX PLUS D (319 patients)
ALLEGRA (314 patients)
PREDNISONE TAB (314 patients)
NITROGLYCERIN (313 patients)
CELEXA (313 patients)
ZOFRAN (311 patients)
TYLENOL (CAPLET) (311 patients)
METFORMIN (306 patients)
GLIPIZIDE (302 patients)
SANDOSTATIN LAR (299 patients)
GLYBURIDE (298 patients)
ZETIA (296 patients)
OXYCODONE HCL (295 patients)
RANITIDINE (294 patients)
DROSPIRENONE AND ETHINYL ESTRADIOL (292 patients)
MULTI-VITAMINS (291 patients)
BEXTRA (291 patients)
CLONAZEPAM (291 patients)
ALEVE (290 patients)
AVONEX (288 patients)
ALENDRONATE SODIUM (288 patients)
PRILOSEC OTC (282 patients)
AVANDIA (282 patients)
SUTENT (279 patients)
ALEVE (CAPLET) (279 patients)
METOPROLOL (277 patients)
PEPCID (275 patients)
AMARYL (270 patients)
MORPHINE (270 patients)
DURAGESIC-100 (268 patients)
FLEXERIL (267 patients)
INSULIN (266 patients)
[THERAPY UNSPECIFIED] (265 patients)
NAPROXEN (264 patients)
DEXAMETHASONE (262 patients)
COMMIT (261 patients)
VICTOZA (258 patients)
COREG (254 patients)
TRAZODONE HCL (254 patients)
ZITHROMAX (254 patients)
TRAMADOL HCL (254 patients)
VALIUM (251 patients)
DECADRON (241 patients)
HEPARIN SODIUM INJECTION (240 patients)
REMICADE (239 patients)
NEXAVAR (235 patients)
KEFLEX (235 patients)
CLONIDINE (234 patients)
REGLAN (231 patients)
ZYPREXA (230 patients)
LANSOPRAZOLE (229 patients)
AMLODIPINE (229 patients)
CALCIUM (UNSPECIFIED) (227 patients)
COZAAR (223 patients)
CLARITIN (222 patients)
CEPHALEXIN (222 patients)
DIAZEPAM (222 patients)
FLOMAX (221 patients)
FENTANYL (220 patients)
SPIRONOLACTONE (220 patients)
PANTOPRAZOLE (218 patients)
HUMALOG (215 patients)
CIPROFLOXACIN (214 patients)
PROMETHAZINE (210 patients)
VITAMINS (UNSPECIFIED) (208 patients)
PRAVACHOL (206 patients)
VITAMIN B-12 (205 patients)
THALIDOMIDE (205 patients)
BENADRYL (199 patients)
XELODA (198 patients)
AZITHROMYCIN (198 patients)
DILAUDID (197 patients)
MOTRIN (195 patients)
CIALIS (194 patients)
EVISTA (194 patients)
HYDROCODONE BITARTRATE (194 patients)
FLONASE (193 patients)
REVLIMID (192 patients)
TRICOR (192 patients)
SYMBICORT (192 patients)
AVELOX (191 patients)
VIAGRA (190 patients)
LOVAZA (190 patients)
TYLENOL-500 (189 patients)
POTASSIUM (188 patients)
TYSABRI (187 patients)
COMPAZINE (186 patients)
WARFARIN SODIUM (185 patients)
LOTREL (185 patients)
ACYCLOVIR (185 patients)
FLUOXETINE (185 patients)
TEGRETOL (184 patients)
ZANTAC 150 (183 patients)
ELAVIL (180 patients)
LOVENOX (180 patients)
ARIMIDEX (180 patients)
DOXYCYCLINE (180 patients)
TOPAMAX (179 patients)
HYDROCODONE (179 patients)
ULTRAM (179 patients)
ALTACE (178 patients)
METOCLOPRAMIDE (176 patients)
VALTREX (176 patients)
CLINDAMYCIN (175 patients)
EXJADE (173 patients)
GLEEVEC (173 patients)
EFFEXOR XR (173 patients)
VELCADE (172 patients)
LIDOCAINE (171 patients)
MOBIC (171 patients)
GLUCOSAMINE (170 patients)
TEMAZEPAM (170 patients)
STRATTERA (168 patients)
DIFLUCAN (168 patients)
MIRALAX (168 patients)
VYTORIN (168 patients)
PREDNISOLONE (167 patients)
GLUCOTROL (166 patients)
Most common side effects for patients taking SORAFENIB (RAF KINASE INHIBITOR):
DIARRHOEA (613 patients) HEPATIC FAILURE (378 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (342 patients)
HEPATIC ENCEPHALOPATHY (320 patients)
FATIGUE (300 patients)
RASH (276 patients)
ASCITES (253 patients)
ABDOMINAL PAIN (237 patients)
DECREASED APPETITE (226 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (198 patients)
PYREXIA (191 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (179 patients)
NAUSEA (165 patients)
HYPERTENSION (160 patients)
ASTHENIA (154 patients)
DEHYDRATION (140 patients)
HEPATIC FUNCTION ABNORMAL (133 patients)
DYSPNOEA (131 patients)
CONFUSIONAL STATE (131 patients)
HYPOKALAEMIA (125 patients)
ALOPECIA (124 patients)
VOMITING (118 patients)
CONSTIPATION (115 patients)
INTERSTITIAL LUNG DISEASE (114 patients)
LEFT VENTRICULAR DYSFUNCTION (113 patients)
DEATH (113 patients)
ENDOCARDITIS (112 patients)
ARTHRALGIA (111 patients)
STOMATITIS (111 patients)
ABDOMINAL PAIN UPPER (110 patients)
JAUNDICE (108 patients)
HEPATIC NEOPLASM MALIGNANT (106 patients)
GASTROINTESTINAL HAEMORRHAGE (106 patients)
RETINAL VASCULAR THROMBOSIS (103 patients)
LOWER GASTROINTESTINAL HAEMORRHAGE (103 patients)
LIVER CARCINOMA RUPTURED (101 patients)
OEDEMA PERIPHERAL (97 patients)
PLEURAL EFFUSION (97 patients)
STAPHYLOCOCCAL INFECTION (96 patients)
PNEUMONIA BACTERIAL (96 patients)
ENTEROBACTER INFECTION (96 patients)
MYOPATHY (95 patients)
DRY MOUTH (94 patients)
PAIN IN EXTREMITY (93 patients)
ANXIETY (90 patients)
MALAISE (89 patients)
PULMONARY EMBOLISM (85 patients)
ANAEMIA (84 patients)
PLATELET COUNT DECREASED (81 patients)
BACK PAIN (79 patients)
SEPSIS (78 patients)
PRURITUS (78 patients)
DUODENAL ULCER (77 patients)
MIGRAINE (76 patients)
MITRAL VALVE INCOMPETENCE (76 patients)
HYPOGLYCAEMIA (76 patients)
C-REACTIVE PROTEIN INCREASED (74 patients)
BLOOD PRESSURE INCREASED (73 patients)
VARICES OESOPHAGEAL (73 patients)
HEADACHE (72 patients)
RETINAL VEIN OCCLUSION (72 patients)
ABASIA (69 patients)
RENAL FAILURE ACUTE (69 patients)
WEIGHT DECREASED (67 patients)
DEEP VEIN THROMBOSIS (67 patients)
DIZZINESS (65 patients)
ERYTHEMA (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (64 patients)
CONVULSION (63 patients)
ALANINE AMINOTRANSFERASE INCREASED (62 patients)
DYSPHONIA (62 patients)
CEREBRAL HAEMORRHAGE (60 patients)
APHAGIA (58 patients)
COLITIS (58 patients)
PNEUMONIA (57 patients)
GASTRIC ULCER (56 patients)
HYPONATRAEMIA (55 patients)
HAEMOGLOBIN DECREASED (53 patients)
RESPIRATORY FAILURE (52 patients)
LUNG DISORDER (52 patients)
CEREBRAL ISCHAEMIA (49 patients)
PARAESTHESIA (49 patients)
BLOOD BILIRUBIN INCREASED (48 patients)
GAIT DISTURBANCE (48 patients)
THYROID CANCER METASTATIC (44 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (43 patients)
PERICARDIAL EFFUSION (41 patients)
THROMBOCYTOPENIA (41 patients)
BLISTER (41 patients)
FEBRILE NEUTROPENIA (40 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (40 patients)
HALLUCINATION (40 patients)
CHILLS (40 patients)
AMMONIA INCREASED (39 patients)
SKIN ULCER (39 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (38 patients)
PAIN (38 patients)
HYPOALBUMINAEMIA (38 patients)
HYPOCALCAEMIA (37 patients)
FALL (37 patients)
POLLAKIURIA (37 patients)
BLOOD PRESSURE DECREASED (37 patients)
SKIN EXFOLIATION (37 patients)
INSOMNIA (36 patients)
CARDIAC ARREST (36 patients)
HYPOAESTHESIA (35 patients)
INFECTIOUS PERITONITIS (35 patients)
MYOCARDIAL INFARCTION (35 patients)
RETINAL VASCULAR DISORDER (34 patients)
RENAL FAILURE (34 patients)
LIPASE INCREASED (34 patients)
HYPERKALAEMIA (33 patients)
HYPERGLYCAEMIA (33 patients)
HAEMOPTYSIS (31 patients)
ATRIAL FIBRILLATION (30 patients)
GENERALISED OEDEMA (30 patients)
FAECAL INCONTINENCE (30 patients)
WHITE BLOOD CELL COUNT DECREASED (30 patients)
CELLULITIS (29 patients)
CHEST PAIN (29 patients)
SOMNOLENCE (29 patients)
HYPERBILIRUBINAEMIA (28 patients)
HYPOTENSION (28 patients)
MUSCLE SPASMS (28 patients)
ABDOMINAL DISTENSION (27 patients)
WHITE BLOOD CELL COUNT INCREASED (27 patients)
VISION BLURRED (27 patients)
HEPATIC PAIN (26 patients)
BLOOD ALBUMIN DECREASED (26 patients)
DYSURIA (25 patients)
RASH GENERALISED (25 patients)
BLOOD SODIUM DECREASED (25 patients)
BLOOD URIC ACID INCREASED (25 patients)
COMA (25 patients)
COUGH (25 patients)
PANCYTOPENIA (25 patients)
ACUTE ABDOMEN (24 patients)
EOSINOPHIL COUNT INCREASED (24 patients)
CEREBROVASCULAR ACCIDENT (24 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (23 patients)
CEREBRAL INFARCTION (23 patients)
HYPOMAGNESAEMIA (23 patients)
RETINAL VEIN THROMBOSIS (23 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (23 patients)
TUMOUR LYSIS SYNDROME (22 patients)
HYPOPHOSPHATAEMIA (22 patients)
INFECTION (22 patients)
ORAL PAIN (22 patients)
BLOOD CREATININE INCREASED (22 patients)
NEUTROPENIA (22 patients)
RENAL IMPAIRMENT (22 patients)
LETHARGY (22 patients)
SKIN TOXICITY (21 patients)
TONGUE BLISTERING (21 patients)
LIVER ABSCESS (21 patients)
HAEMATEMESIS (21 patients)
OESOPHAGEAL VARICES HAEMORRHAGE (20 patients)
MENTAL IMPAIRMENT (20 patients)
NERVOUSNESS (20 patients)
NEPHROTIC SYNDROME (20 patients)
HYPOPHAGIA (20 patients)
ADRENAL INSUFFICIENCY (19 patients)
DRY SKIN (19 patients)
BLOOD AMYLASE INCREASED (19 patients)
OEDEMA (19 patients)
INFECTIOUS PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
COMA HEPATIC (19 patients)
HEART RATE INCREASED (18 patients)
HYPERTENSIVE CRISIS (18 patients)
MYALGIA (18 patients)
ECZEMA (18 patients)
URINARY TRACT INFECTION (18 patients)
NEUROMYOPATHY (18 patients)
MEDICAL DEVICE COMPLICATION (18 patients)
DIVERTICULITIS (18 patients)
OSTEOMYELITIS (18 patients)
CEREBRAL ATROPHY (18 patients)
CEREBRAL VENTRICLE DILATATION (18 patients)
DIABETIC FOOT INFECTION (18 patients)
NECK PAIN (18 patients)
OLIGURIA (17 patients)
GASTROINTESTINAL DISORDER (17 patients)
HAEMATOCHEZIA (17 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (17 patients)
HYPOTHYROIDISM (17 patients)
TRANSAMINASES INCREASED (17 patients)
OROPHARYNGEAL PAIN (17 patients)
CHRONIC MYELOID LEUKAEMIA (17 patients)
NEOPLASM PROGRESSION (17 patients)
METASTASES TO ADRENALS (16 patients)
LYMPHOCYTE COUNT DECREASED (16 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (16 patients)
MULTI-ORGAN FAILURE (16 patients)
FEAR (16 patients)
PANCREATIC CARCINOMA (16 patients)
HYPERSOMNIA (16 patients)
EPILEPSY (16 patients)
SUBARACHNOID HAEMORRHAGE (16 patients)
METASTASES TO LUNG (16 patients)
TACHYCARDIA (16 patients)
MUSCULAR WEAKNESS (16 patients)
KLEBSIELLA SEPSIS (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
DYSGEUSIA (16 patients)
LUNG INFECTION (16 patients)
FAECES DISCOLOURED (16 patients)
PAIN OF SKIN (16 patients)
SPINAL FRACTURE (16 patients)
PANIC REACTION (16 patients)
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Boating hobby lessons in Tyngsboro
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Airplane rentals in Tyngsboro
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Biology tutoring in Tyngsboro
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