Is FEBRILE NEUTROPENIA a side effect of SORAFENIB (RAF KINASE INHIBITOR) ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of SORAFENIB (RAF KINASE INHIBITOR) patients who developed FEBRILE NEUTROPENIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 40 individuals taking SORAFENIB (RAF KINASE INHIBITOR) reported FEBRILE NEUTROPENIA to the FDA. A total of 3329 SORAFENIB (RAF KINASE INHIBITOR) drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between SORAFENIB (RAF KINASE INHIBITOR) and FEBRILE NEUTROPENIA. In doing so, we compare SORAFENIB (RAF KINASE INHIBITOR) with other drugs that cause FEBRILE NEUTROPENIA, to help you evaluate whether or not SORAFENIB (RAF KINASE INHIBITOR) causes FEBRILE NEUTROPENIA. Likewise, this page shows the most highly-reported side effects of SORAFENIB (RAF KINASE INHIBITOR), so you can see if FEBRILE NEUTROPENIA ranks among SORAFENIB (RAF KINASE INHIBITOR)'s most well-known side effects.

Summary Statistics
Reports of SORAFENIB (RAF KINASE INHIBITOR) causing FEBRILE NEUTROPENIA: 40
Reports of any side effect of SORAFENIB (RAF KINASE INHIBITOR) : 3329
Percentage of SORAFENIB (RAF KINASE INHIBITOR) patients where FEBRILE NEUTROPENIA is a reported side effect: 1.2016%

FDA reports of any drug causing FEBRILE NEUTROPENIA : 17428
Average percentage for all medicated patients where FEBRILE NEUTROPENIA is reported as a complication: 0.1092%

Physician opinion on SORAFENIB (RAF KINASE INHIBITOR) as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing SORAFENIB (RAF KINASE INHIBITOR):

HEPATIC NEOPLASM MALIGNANT ( 770 patients )
RENAL CELL CARCINOMA ( 114 patients )
THYROID CANCER ( 65 patients )
METASTATIC RENAL CELL CARCINOMA ( 44 patients )
THYROID CANCER METASTATIC ( 35 patients )
BREAST CANCER ( 31 patients )
BREAST CANCER METASTATIC ( 27 patients )
GASTRIC CANCER ( 25 patients )
NON-SMALL CELL LUNG CANCER ( 25 patients )
COLORECTAL CANCER METASTATIC ( 22 patients )
RENAL CANCER ( 17 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 14 patients )
BILE DUCT CANCER ( 14 patients )
SALIVARY GLAND CANCER ( 7 patients )
HEPATIC CANCER METASTATIC ( 7 patients )
COLORECTAL CANCER ( 7 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 6 patients )
RECTAL CANCER ( 5 patients )
PANCREATIC CARCINOMA ( 4 patients )
PROSTATE CANCER ( 4 patients )
INTRAOCULAR MELANOMA ( 4 patients )
HEPATIC NEOPLASM MALIGNANT RECURRENT ( 3 patients )
NEOPLASM ( 3 patients )
LIVER DISORDER ( 3 patients )
ANGIOSARCOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 3 patients )
METASTASES TO LUNG ( 3 patients )
HEPATIC NEOPLASM MALIGNANT NON-RESECTABLE ( 3 patients )
COLORECTAL CANCER STAGE IV ( 3 patients )
NEOPLASM MALIGNANT ( 3 patients )
GALLBLADDER CANCER METASTATIC ( 3 patients )
BILIARY CANCER METASTATIC ( 3 patients )
METASTASIS ( 3 patients )
COLON CANCER METASTATIC ( 2 patients )
HYPOPHARYNGEAL CANCER ( 2 patients )
DESMOID TUMOUR ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
ACUTE MYELOID LEUKAEMIA (IN REMISSION) ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
OESOPHAGEAL CARCINOMA ( 2 patients )
METASTATIC MALIGNANT MELANOMA ( 2 patients )
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED ( 2 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 2 patients )
ANGINA PECTORIS ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
OSTEOSARCOMA METASTATIC ( 2 patients )
BONE SARCOMA ( 2 patients )
METASTATIC OCULAR MELANOMA ( 2 patients )
METASTATIC SALIVARY GLAND CANCER ( 2 patients )
TONSIL CANCER ( 2 patients )
MYELODYSPLASTIC SYNDROME ( 1 patients )
PROSTATE CANCER METASTATIC ( 1 patients )
GALLBLADDER CANCER ( 1 patients )
NEUROENDOCRINE TUMOUR ( 1 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 1 patients )
GLIOMA ( 1 patients )
BLADDER CANCER ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
CAROTID ARTERY DISEASE ( 1 patients )
HEPATOBLASTOMA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
ACUTE MYELOID LEUKAEMIA ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
RENAL CANCER METASTATIC ( 1 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 1 patients )
NEUROENDOCRINE CARCINOMA OF THE SKIN ( 1 patients )
MALIGNANT HISTIOCYTOSIS ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 1 patients )
SARCOMA ( 1 patients )
GERM CELL CANCER ( 1 patients )
OESOPHAGEAL ADENOCARCINOMA ( 1 patients )
SQUAMOUS CELL CARCINOMA ( 1 patients )
HEAD AND NECK CANCER ( 1 patients )
OVARIAN EPITHELIAL CANCER ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with FEBRILE NEUTROPENIA:

CYCLOPHOSPHAMIDE (4212 patients)
DOXORUBICIN HCL (2297 patients)
VINCRISTINE (2160 patients)
CISPLATIN (1849 patients)
ETOPOSIDE (1593 patients)
DEXAMETHASONE (1560 patients)
RITUXIMAB (1559 patients)
CYTARABINE (1546 patients)
PREDNISONE (1409 patients)
FLUOROURACIL (1378 patients)
CARBOPLATIN (1378 patients)
METHOTREXATE (1247 patients)
DOCETAXEL (1183 patients)
NEULASTA (1144 patients)
NEUPOGEN (1059 patients)
ACYCLOVIR (1037 patients)
PREDNISONE TAB (957 patients)
ALLOPURINOL (956 patients)
FLUCONAZOLE (908 patients)
ACETAMINOPHEN (888 patients)
REVLIMID (885 patients)
ASPIRIN (814 patients)
PREDNISOLONE (805 patients)
PACLITAXEL (779 patients)
OMEPRAZOLE (778 patients)
ZOFRAN (693 patients)
VIDAZA (671 patients)
DECADRON (662 patients)
TAXOTERE (635 patients)
CYCLOSPORINE (570 patients)
ONDANSETRON (570 patients)
MYLOTARG (566 patients)
ATIVAN (534 patients)
FOLIC ACID (517 patients)
RITUXAN (513 patients)
IFOSFAMIDE (496 patients)
BEVACIZUMAB (494 patients)
VANCOMYCIN (494 patients)
VINCRISTINE SULFATE (466 patients)
LEUCOVORIN CALCIUM (460 patients)
FLUDARABINE PHOSPHATE (459 patients)
COMPAZINE (448 patients)
VELCADE (446 patients)
POTASSIUM CHLORIDE (443 patients)
CAPECITABINE (443 patients)
TAXOL (437 patients)
LASIX (432 patients)
OXALIPLATIN (429 patients)
LORAZEPAM (428 patients)
LEVOFLOXACIN (414 patients)
MORPHINE (413 patients)
DOXORUBICIN HYDROCHLORIDE (412 patients)
ADRIAMYCIN PFS (400 patients)
FUROSEMIDE (390 patients)
DIFLUCAN (386 patients)
CIPROFLOXACIN (385 patients)
AVASTIN (381 patients)
MABTHERA (379 patients)
EPIRUBICIN (375 patients)
THYMOGLOBULIN (372 patients)
CETUXIMAB (367 patients)
BLINDED PLACEBO (364 patients)
IRINOTECAN HCL (358 patients)
TRASTUZUMAB (356 patients)
PROTONIX (354 patients)
ZOMETA (348 patients)
FILGRASTIM (347 patients)
MEROPENEM (338 patients)
KYTRIL (336 patients)
LANSOPRAZOLE (321 patients)
NEXIUM (321 patients)
FLUDARA (319 patients)
METOCLOPRAMIDE (318 patients)
BLINDED BEVACIZUMAB (314 patients)
AMBIEN (312 patients)
MESNA (303 patients)
PANITUMUMAB (302 patients)
CYTOXAN (302 patients)
HERCEPTIN (290 patients)
BACTRIM (287 patients)
LISINOPRIL (283 patients)
BLINDED RITUXIMAB (282 patients)
DEXAMETHASONE TAB (279 patients)
PANTOPRAZOLE SODIUM (275 patients)
OXYCONTIN (274 patients)
SIMVASTATIN (274 patients)
ATENOLOL (273 patients)
MAGNESIUM OXIDE (271 patients)
OXYCODONE HCL (265 patients)
COUMADIN (263 patients)
PLATELETS (263 patients)
SODIUM CHLORIDE (262 patients)
VALTREX (261 patients)
TACROLIMUS (261 patients)
CAMPATH (260 patients)
LEVAQUIN (256 patients)
FAMOTIDINE (254 patients)
PRILOSEC (254 patients)
AREDIA (249 patients)
LAPATINIB (248 patients)
LIPITOR (247 patients)
XELODA (246 patients)
NYSTATIN (245 patients)
SYNTHROID (244 patients)
PEGFILGRASTIM (243 patients)
ITRACONAZOLE (239 patients)
XANAX (238 patients)
PROGRAF (234 patients)
HYDROCHLOROTHIAZIDE (231 patients)
IDARUBICIN HCL (229 patients)
GABAPENTIN (228 patients)
TEMOZOLOMIDE (228 patients)
GEMCITABINE (228 patients)
ZANTAC (227 patients)
RADIATION THERAPY (227 patients)
VORICONAZOLE (223 patients)
LOVENOX (222 patients)
EXJADE (221 patients)
CEFEPIME (220 patients)
DAUNORUBICIN HCL (217 patients)
COLACE (215 patients)
DIPHENHYDRAMINE HCL (215 patients)
HEPARIN (215 patients)
ALKERAN (214 patients)
HYDROCORTISONE (214 patients)
BENADRYL (214 patients)
LEVOTHYROXINE SODIUM (212 patients)
DOXORUBICIN (208 patients)
ZOLOFT (207 patients)
METHYLPREDNISOLONE (206 patients)
ALBUTEROL (204 patients)
NORVASC (203 patients)
RANITIDINE (202 patients)
ZOVIRAX (202 patients)
COTRIM (200 patients)
VITAMIN B-12 (199 patients)
ALIMTA (198 patients)
PANTOPRAZOLE (196 patients)
IBUPROFEN (192 patients)
MELPHALAN HYDROCHLORIDE (192 patients)
MAXIPIME (191 patients)
METFORMIN HCL (190 patients)
AMLODIPINE (189 patients)
FENTANYL (188 patients)
MELPHALAN (185 patients)
PERCOCET (183 patients)
THALIDOMIDE (181 patients)
IMODIUM (180 patients)
NEURONTIN (179 patients)
METHYLPREDNISOLONE SODIUM SUCCINATE (179 patients)
EMEND (175 patients)
LACTULOSE (175 patients)
AFINITOR (175 patients)
PARACETAMOL (173 patients)
MAGNESIUM SULFATE (173 patients)
THALOMID (172 patients)
MITOXANTRONE (169 patients)
AMPHOTERICIN B (168 patients)
SULFAMETHOXAZOLE AND TRIMETHOPRIM (165 patients)
SOLIRIS (164 patients)
PROCHLORPERAZINE (163 patients)
METRONIDAZOLE (161 patients)
FLUDARABINE (158 patients)
GRAN (158 patients)
MYCOPHENOLATE MOFETIL (157 patients)
MULTI-VITAMINS (157 patients)
PEPCID (155 patients)
DILAUDID (155 patients)
TRAMADOL HCL (154 patients)
WARFARIN SODIUM (154 patients)
CLOFARABINE (154 patients)
AZACITIDINE (154 patients)
ERBITUX (153 patients)
RED BLOOD CELLS (150 patients)
SENOKOT (149 patients)
REMICADE (148 patients)
CIPRO (147 patients)
ZOSYN (146 patients)
BUSULFAN (146 patients)
SOLU-MEDROL (146 patients)
METOPROLOL TARTRATE (146 patients)
NEUTROGIN (145 patients)
HYDROCORTISONE SODIUM SUCCINATE (145 patients)
VICODIN (145 patients)
BLEOMYCIN SULFATE (145 patients)
GEMZAR (144 patients)
CLOLAR (144 patients)
MULTI-VITAMIN (144 patients)
NOVANTRONE (143 patients)
GLEEVEC (142 patients)
HALAVEN (142 patients)
OFATUMUMAB (140 patients)
PEMETREXED (140 patients)
PREVACID (139 patients)
GRANISETRON (138 patients)
DACTINOMYCIN (138 patients)
TOPROL-XL (137 patients)
TREANDA (137 patients)
URSO 250 (136 patients)
MUCOSTA (134 patients)
ZOCOR (134 patients)
ARANESP (133 patients)
TYLENOL (132 patients)
MORPHINE SULFATE (132 patients)
FLOMAX (132 patients)
REGLAN (130 patients)
DOXIL (129 patients)
ALPRAZOLAM (129 patients)
DECITABINE (128 patients)
LENOGRASTIM (128 patients)

Most common side effects for patients taking SORAFENIB (RAF KINASE INHIBITOR):

DIARRHOEA (613 patients)
HEPATIC FAILURE (378 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (342 patients)
HEPATIC ENCEPHALOPATHY (320 patients)
FATIGUE (300 patients)
RASH (276 patients)
ASCITES (253 patients)
ABDOMINAL PAIN (237 patients)
DECREASED APPETITE (226 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (198 patients)
PYREXIA (191 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (179 patients)
NAUSEA (165 patients)
HYPERTENSION (160 patients)
ASTHENIA (154 patients)
DEHYDRATION (140 patients)
HEPATIC FUNCTION ABNORMAL (133 patients)
DYSPNOEA (131 patients)
CONFUSIONAL STATE (131 patients)
HYPOKALAEMIA (125 patients)
ALOPECIA (124 patients)
VOMITING (118 patients)
CONSTIPATION (115 patients)
INTERSTITIAL LUNG DISEASE (114 patients)
LEFT VENTRICULAR DYSFUNCTION (113 patients)
DEATH (113 patients)
ENDOCARDITIS (112 patients)
ARTHRALGIA (111 patients)
STOMATITIS (111 patients)
ABDOMINAL PAIN UPPER (110 patients)
JAUNDICE (108 patients)
HEPATIC NEOPLASM MALIGNANT (106 patients)
GASTROINTESTINAL HAEMORRHAGE (106 patients)
RETINAL VASCULAR THROMBOSIS (103 patients)
LOWER GASTROINTESTINAL HAEMORRHAGE (103 patients)
LIVER CARCINOMA RUPTURED (101 patients)
OEDEMA PERIPHERAL (97 patients)
PLEURAL EFFUSION (97 patients)
STAPHYLOCOCCAL INFECTION (96 patients)
PNEUMONIA BACTERIAL (96 patients)
ENTEROBACTER INFECTION (96 patients)
MYOPATHY (95 patients)
DRY MOUTH (94 patients)
PAIN IN EXTREMITY (93 patients)
ANXIETY (90 patients)
MALAISE (89 patients)
PULMONARY EMBOLISM (85 patients)
ANAEMIA (84 patients)
PLATELET COUNT DECREASED (81 patients)
BACK PAIN (79 patients)
SEPSIS (78 patients)
PRURITUS (78 patients)
DUODENAL ULCER (77 patients)
MIGRAINE (76 patients)
MITRAL VALVE INCOMPETENCE (76 patients)
HYPOGLYCAEMIA (76 patients)
C-REACTIVE PROTEIN INCREASED (74 patients)
BLOOD PRESSURE INCREASED (73 patients)
VARICES OESOPHAGEAL (73 patients)
HEADACHE (72 patients)
RETINAL VEIN OCCLUSION (72 patients)
ABASIA (69 patients)
RENAL FAILURE ACUTE (69 patients)
WEIGHT DECREASED (67 patients)
DEEP VEIN THROMBOSIS (67 patients)
DIZZINESS (65 patients)
ERYTHEMA (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (64 patients)
CONVULSION (63 patients)
ALANINE AMINOTRANSFERASE INCREASED (62 patients)
DYSPHONIA (62 patients)
CEREBRAL HAEMORRHAGE (60 patients)
APHAGIA (58 patients)
COLITIS (58 patients)
PNEUMONIA (57 patients)
GASTRIC ULCER (56 patients)
HYPONATRAEMIA (55 patients)
HAEMOGLOBIN DECREASED (53 patients)
RESPIRATORY FAILURE (52 patients)
LUNG DISORDER (52 patients)
CEREBRAL ISCHAEMIA (49 patients)
PARAESTHESIA (49 patients)
BLOOD BILIRUBIN INCREASED (48 patients)
GAIT DISTURBANCE (48 patients)
THYROID CANCER METASTATIC (44 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (43 patients)
PERICARDIAL EFFUSION (41 patients)
THROMBOCYTOPENIA (41 patients)
BLISTER (41 patients)
FEBRILE NEUTROPENIA (40 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (40 patients)
HALLUCINATION (40 patients)
CHILLS (40 patients)
AMMONIA INCREASED (39 patients)
SKIN ULCER (39 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (38 patients)
PAIN (38 patients)
HYPOALBUMINAEMIA (38 patients)
HYPOCALCAEMIA (37 patients)
FALL (37 patients)
POLLAKIURIA (37 patients)
BLOOD PRESSURE DECREASED (37 patients)
SKIN EXFOLIATION (37 patients)
INSOMNIA (36 patients)
CARDIAC ARREST (36 patients)
HYPOAESTHESIA (35 patients)
INFECTIOUS PERITONITIS (35 patients)
MYOCARDIAL INFARCTION (35 patients)
RETINAL VASCULAR DISORDER (34 patients)
RENAL FAILURE (34 patients)
LIPASE INCREASED (34 patients)
HYPERKALAEMIA (33 patients)
HYPERGLYCAEMIA (33 patients)
HAEMOPTYSIS (31 patients)
ATRIAL FIBRILLATION (30 patients)
GENERALISED OEDEMA (30 patients)
FAECAL INCONTINENCE (30 patients)
WHITE BLOOD CELL COUNT DECREASED (30 patients)
CELLULITIS (29 patients)
CHEST PAIN (29 patients)
SOMNOLENCE (29 patients)
HYPERBILIRUBINAEMIA (28 patients)
HYPOTENSION (28 patients)
MUSCLE SPASMS (28 patients)
ABDOMINAL DISTENSION (27 patients)
WHITE BLOOD CELL COUNT INCREASED (27 patients)
VISION BLURRED (27 patients)
HEPATIC PAIN (26 patients)
BLOOD ALBUMIN DECREASED (26 patients)
DYSURIA (25 patients)
RASH GENERALISED (25 patients)
BLOOD SODIUM DECREASED (25 patients)
BLOOD URIC ACID INCREASED (25 patients)
COMA (25 patients)
COUGH (25 patients)
PANCYTOPENIA (25 patients)
ACUTE ABDOMEN (24 patients)
EOSINOPHIL COUNT INCREASED (24 patients)
CEREBROVASCULAR ACCIDENT (24 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (23 patients)
CEREBRAL INFARCTION (23 patients)
HYPOMAGNESAEMIA (23 patients)
RETINAL VEIN THROMBOSIS (23 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (23 patients)
TUMOUR LYSIS SYNDROME (22 patients)
HYPOPHOSPHATAEMIA (22 patients)
INFECTION (22 patients)
ORAL PAIN (22 patients)
BLOOD CREATININE INCREASED (22 patients)
NEUTROPENIA (22 patients)
RENAL IMPAIRMENT (22 patients)
LETHARGY (22 patients)
SKIN TOXICITY (21 patients)
TONGUE BLISTERING (21 patients)
LIVER ABSCESS (21 patients)
HAEMATEMESIS (21 patients)
OESOPHAGEAL VARICES HAEMORRHAGE (20 patients)
MENTAL IMPAIRMENT (20 patients)
NERVOUSNESS (20 patients)
NEPHROTIC SYNDROME (20 patients)
HYPOPHAGIA (20 patients)
ADRENAL INSUFFICIENCY (19 patients)
DRY SKIN (19 patients)
BLOOD AMYLASE INCREASED (19 patients)
OEDEMA (19 patients)
INFECTIOUS PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
COMA HEPATIC (19 patients)
HEART RATE INCREASED (18 patients)
HYPERTENSIVE CRISIS (18 patients)
MYALGIA (18 patients)
ECZEMA (18 patients)
URINARY TRACT INFECTION (18 patients)
NEUROMYOPATHY (18 patients)
MEDICAL DEVICE COMPLICATION (18 patients)
DIVERTICULITIS (18 patients)
OSTEOMYELITIS (18 patients)
CEREBRAL ATROPHY (18 patients)
CEREBRAL VENTRICLE DILATATION (18 patients)
DIABETIC FOOT INFECTION (18 patients)
NECK PAIN (18 patients)
OLIGURIA (17 patients)
GASTROINTESTINAL DISORDER (17 patients)
HAEMATOCHEZIA (17 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (17 patients)
HYPOTHYROIDISM (17 patients)
TRANSAMINASES INCREASED (17 patients)
OROPHARYNGEAL PAIN (17 patients)
CHRONIC MYELOID LEUKAEMIA (17 patients)
NEOPLASM PROGRESSION (17 patients)
METASTASES TO ADRENALS (16 patients)
LYMPHOCYTE COUNT DECREASED (16 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (16 patients)
MULTI-ORGAN FAILURE (16 patients)
FEAR (16 patients)
PANCREATIC CARCINOMA (16 patients)
HYPERSOMNIA (16 patients)
EPILEPSY (16 patients)
SUBARACHNOID HAEMORRHAGE (16 patients)
METASTASES TO LUNG (16 patients)
TACHYCARDIA (16 patients)
MUSCULAR WEAKNESS (16 patients)
KLEBSIELLA SEPSIS (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
DYSGEUSIA (16 patients)
LUNG INFECTION (16 patients)
FAECES DISCOLOURED (16 patients)
PAIN OF SKIN (16 patients)
SPINAL FRACTURE (16 patients)
PANIC REACTION (16 patients)

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