Is GASTROINTESTINAL HAEMORRHAGE a side effect of SORAFENIB (RAF KINASE INHIBITOR) ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of SORAFENIB (RAF KINASE INHIBITOR) patients who developed GASTROINTESTINAL HAEMORRHAGE.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 106 individuals taking SORAFENIB (RAF KINASE INHIBITOR) reported GASTROINTESTINAL HAEMORRHAGE to the FDA. A total of 3329 SORAFENIB (RAF KINASE INHIBITOR) drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between SORAFENIB (RAF KINASE INHIBITOR) and GASTROINTESTINAL HAEMORRHAGE. In doing so, we compare SORAFENIB (RAF KINASE INHIBITOR) with other drugs that cause GASTROINTESTINAL HAEMORRHAGE, to help you evaluate whether or not SORAFENIB (RAF KINASE INHIBITOR) causes GASTROINTESTINAL HAEMORRHAGE. Likewise, this page shows the most highly-reported side effects of SORAFENIB (RAF KINASE INHIBITOR), so you can see if GASTROINTESTINAL HAEMORRHAGE ranks among SORAFENIB (RAF KINASE INHIBITOR)'s most well-known side effects.

Summary Statistics
Reports of SORAFENIB (RAF KINASE INHIBITOR) causing GASTROINTESTINAL HAEMORRHAGE: 106
Reports of any side effect of SORAFENIB (RAF KINASE INHIBITOR) : 3329
Percentage of SORAFENIB (RAF KINASE INHIBITOR) patients where GASTROINTESTINAL HAEMORRHAGE is a reported side effect: 3.1841%

FDA reports of any drug causing GASTROINTESTINAL HAEMORRHAGE : 23182
Average percentage for all medicated patients where GASTROINTESTINAL HAEMORRHAGE is reported as a complication: 0.1453%

Physician opinion on SORAFENIB (RAF KINASE INHIBITOR) as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing SORAFENIB (RAF KINASE INHIBITOR):

HEPATIC NEOPLASM MALIGNANT ( 770 patients )
RENAL CELL CARCINOMA ( 114 patients )
THYROID CANCER ( 65 patients )
METASTATIC RENAL CELL CARCINOMA ( 44 patients )
THYROID CANCER METASTATIC ( 35 patients )
BREAST CANCER ( 31 patients )
BREAST CANCER METASTATIC ( 27 patients )
GASTRIC CANCER ( 25 patients )
NON-SMALL CELL LUNG CANCER ( 25 patients )
COLORECTAL CANCER METASTATIC ( 22 patients )
RENAL CANCER ( 17 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 14 patients )
BILE DUCT CANCER ( 14 patients )
SALIVARY GLAND CANCER ( 7 patients )
HEPATIC CANCER METASTATIC ( 7 patients )
COLORECTAL CANCER ( 7 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 6 patients )
RECTAL CANCER ( 5 patients )
PANCREATIC CARCINOMA ( 4 patients )
PROSTATE CANCER ( 4 patients )
INTRAOCULAR MELANOMA ( 4 patients )
HEPATIC NEOPLASM MALIGNANT RECURRENT ( 3 patients )
NEOPLASM ( 3 patients )
LIVER DISORDER ( 3 patients )
ANGIOSARCOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 3 patients )
METASTASES TO LUNG ( 3 patients )
HEPATIC NEOPLASM MALIGNANT NON-RESECTABLE ( 3 patients )
COLORECTAL CANCER STAGE IV ( 3 patients )
NEOPLASM MALIGNANT ( 3 patients )
GALLBLADDER CANCER METASTATIC ( 3 patients )
BILIARY CANCER METASTATIC ( 3 patients )
METASTASIS ( 3 patients )
COLON CANCER METASTATIC ( 2 patients )
HYPOPHARYNGEAL CANCER ( 2 patients )
DESMOID TUMOUR ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
ACUTE MYELOID LEUKAEMIA (IN REMISSION) ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
OESOPHAGEAL CARCINOMA ( 2 patients )
METASTATIC MALIGNANT MELANOMA ( 2 patients )
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED ( 2 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 2 patients )
ANGINA PECTORIS ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
OSTEOSARCOMA METASTATIC ( 2 patients )
BONE SARCOMA ( 2 patients )
METASTATIC OCULAR MELANOMA ( 2 patients )
METASTATIC SALIVARY GLAND CANCER ( 2 patients )
TONSIL CANCER ( 2 patients )
MYELODYSPLASTIC SYNDROME ( 1 patients )
PROSTATE CANCER METASTATIC ( 1 patients )
GALLBLADDER CANCER ( 1 patients )
NEUROENDOCRINE TUMOUR ( 1 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 1 patients )
GLIOMA ( 1 patients )
BLADDER CANCER ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
CAROTID ARTERY DISEASE ( 1 patients )
HEPATOBLASTOMA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
ACUTE MYELOID LEUKAEMIA ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
RENAL CANCER METASTATIC ( 1 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 1 patients )
NEUROENDOCRINE CARCINOMA OF THE SKIN ( 1 patients )
MALIGNANT HISTIOCYTOSIS ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 1 patients )
SARCOMA ( 1 patients )
GERM CELL CANCER ( 1 patients )
OESOPHAGEAL ADENOCARCINOMA ( 1 patients )
SQUAMOUS CELL CARCINOMA ( 1 patients )
HEAD AND NECK CANCER ( 1 patients )
OVARIAN EPITHELIAL CANCER ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with GASTROINTESTINAL HAEMORRHAGE:

ASPIRIN (4135 patients)
PRADAXA (2404 patients)
VIOXX (2145 patients)
HEPARIN SODIUM INJECTION (1681 patients)
LASIX (1458 patients)
PLAVIX (1399 patients)
COUMADIN (1362 patients)
WARFARIN SODIUM (1213 patients)
FUROSEMIDE (1138 patients)
FOSAMAX (1138 patients)
PREDNISONE (1055 patients)
OMEPRAZOLE (1037 patients)
PREDNISOLONE (1004 patients)
LISINOPRIL (952 patients)
SIMVASTATIN (882 patients)
ACETAMINOPHEN (811 patients)
CELEBREX (796 patients)
LIPITOR (792 patients)
ALLOPURINOL (789 patients)
IBUPROFEN (748 patients)
DIGOXIN (718 patients)
NEXIUM (703 patients)
PROTONIX (688 patients)
POTASSIUM CHLORIDE (679 patients)
ATENOLOL (628 patients)
FOLIC ACID (608 patients)
ZOMETA (600 patients)
PRILOSEC (573 patients)
METHOTREXATE (570 patients)
NORVASC (570 patients)
SYNTHROID (565 patients)
ACCUTANE (543 patients)
DEXAMETHASONE (514 patients)
HYDROCHLOROTHIAZIDE (511 patients)
DIANEAL (496 patients)
LEVOTHYROXINE SODIUM (490 patients)
ZOCOR (489 patients)
AREDIA (445 patients)
AMLODIPINE (442 patients)
HEPARIN (440 patients)
TOPROL-XL (438 patients)
LANSOPRAZOLE (429 patients)
ALBUTEROL (424 patients)
NITROGLYCERIN (421 patients)
RAMIPRIL (416 patients)
REVLIMID (412 patients)
HUMIRA (411 patients)
AMBIEN (400 patients)
REMICADE (398 patients)
FLUOROURACIL (385 patients)
METOPROLOL TARTRATE (380 patients)
NEURONTIN (373 patients)
CLOPIDOGREL (373 patients)
LOVENOX (371 patients)
PREVACID (366 patients)
PREDNISONE TAB (365 patients)
LORAZEPAM (360 patients)
ATIVAN (358 patients)
LEVAQUIN (357 patients)
MORPHINE (356 patients)
GLEEVEC (356 patients)
INSULIN (355 patients)
ZOFRAN (353 patients)
NEXAVAR (349 patients)
OXYCONTIN (346 patients)
NAPROXEN (342 patients)
XANAX (341 patients)
TRACLEER (335 patients)
XARELTO (335 patients)
FERROUS SULFATE TAB (333 patients)
VANCOMYCIN (329 patients)
EXJADE (327 patients)
VICODIN (326 patients)
CYCLOPHOSPHAMIDE (326 patients)
METFORMIN HCL (322 patients)
VITAMIN D (322 patients)
DECADRON (317 patients)
SPIRONOLACTONE (314 patients)
CARBOPLATIN (313 patients)
MYCOPHENOLATE MOFETIL (313 patients)
SEROQUEL (309 patients)
TACROLIMUS (306 patients)
PANTOPRAZOLE (304 patients)
ZOLOFT (297 patients)
ALDACTONE (296 patients)
CISPLATIN (296 patients)
MULTI-VITAMINS (294 patients)
LEXAPRO (290 patients)
FENTANYL (287 patients)
HEPARIN SODIUM (287 patients)
ACETYLSALICYLIC ACID SRT (281 patients)
CALCIUM CARBONATE (269 patients)
AVASTIN (269 patients)
DIOVAN (267 patients)
COREG (267 patients)
COLACE (266 patients)
METOPROLOL (265 patients)
LOPRESSOR (262 patients)
ZANTAC (261 patients)
PERCOCET (260 patients)
FAMOTIDINE (260 patients)
LANTUS (253 patients)
PREMARIN (248 patients)
ASCORBIC ACID (247 patients)
VELCADE (247 patients)
TRAMADOL HCL (247 patients)
FLUCONAZOLE (244 patients)
GABAPENTIN (243 patients)
ENALAPRIL MALEATE (243 patients)
VOLTAREN (242 patients)
WARFARIN (237 patients)
VITAMIN B-12 (237 patients)
DURAGESIC-100 (236 patients)
ATORVASTATIN CALCIUM (236 patients)
ADVAIR DISKUS 100/50 (233 patients)
CYCLOSPORINE (232 patients)
OXYCODONE HCL (230 patients)
REGLAN (230 patients)
PROCRIT (229 patients)
CRESTOR (227 patients)
CLOPIDOGREL BISULFATE (225 patients)
TYLENOL (CAPLET) (223 patients)
TYLENOL (222 patients)
CARVEDILOL (220 patients)
NPLATE (220 patients)
VITAMIN E (220 patients)
SPIRIVA (217 patients)
VINCRISTINE (216 patients)
METHYLPREDNISOLONE (216 patients)
FORTEO (215 patients)
COMPAZINE (215 patients)
ZYPREXA (213 patients)
COZAAR (213 patients)
OXALIPLATIN (213 patients)
TASIGNA (213 patients)
PAXIL (210 patients)
MULTI-VITAMIN (209 patients)
ARANESP (209 patients)
CIPROFLOXACIN (208 patients)
ACYCLOVIR (207 patients)
LORTAB (207 patients)
CYMBALTA (206 patients)
CALCIUM (206 patients)
AMOXICILLIN (206 patients)
RANITIDINE (205 patients)
SUTENT (205 patients)
DICLOFENAC SODIUM (205 patients)
AVONEX (205 patients)
ACTOS (202 patients)
METOCLOPRAMIDE (200 patients)
BEVACIZUMAB (200 patients)
BISOPROLOL FUMARATE (199 patients)
ENOXAPARIN SODIUM (198 patients)
DIFLUCAN (197 patients)
ACTONEL (193 patients)
CITALOPRAM HYDROBROMIDE (193 patients)
METOPROLOL SUCCINATE (192 patients)
SORAFENIB (192 patients)
CYTARABINE (192 patients)
LYRICA (192 patients)
IRON (191 patients)
PEPCID (190 patients)
FLOMAX (190 patients)
FLAGYL (187 patients)
GLUCOPHAGE (187 patients)
LACTULOSE (185 patients)
GLYBURIDE (184 patients)
MOBIC (181 patients)
SOLU-MEDROL (181 patients)
DOXORUBICIN HCL (180 patients)
DILAUDID (180 patients)
EPOGEN (179 patients)
AVANDIA (179 patients)
BEXTRA (178 patients)
AMIODARONE HCL (177 patients)
PROGRAF (177 patients)
CLONAZEPAM (176 patients)
SANDOSTATIN LAR (176 patients)
MAGNESIUM OXIDE (175 patients)
CAPECITABINE (175 patients)
NIFEDIPINE (174 patients)
GLIPIZIDE (173 patients)
SOLIRIS (173 patients)
MEGACE (171 patients)
IMODIUM (170 patients)
NEORAL (168 patients)
ALTACE (168 patients)
DIAZEPAM (167 patients)
PANTOPRAZOLE SODIUM (167 patients)
CELEXA (165 patients)
VERAPAMIL (165 patients)
ALPRAZOLAM (164 patients)
TORSEMIDE (164 patients)
ENBREL (159 patients)
BACTRIM (159 patients)
CLONIDINE (158 patients)
PROZAC (157 patients)
ALLEGRA (157 patients)
METRONIDAZOLE (157 patients)
ARICEPT (156 patients)
FLEXERIL (156 patients)
PROPOFOL (154 patients)
LEUCOVORIN CALCIUM (153 patients)
EFFEXOR (152 patients)
BENADRYL (152 patients)
MOTRIN (150 patients)
POTASSIUM (150 patients)
ALENDRONATE SODIUM (149 patients)
ONDANSETRON (149 patients)
CLOZARIL (149 patients)

Most common side effects for patients taking SORAFENIB (RAF KINASE INHIBITOR):

DIARRHOEA (613 patients)
HEPATIC FAILURE (378 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (342 patients)
HEPATIC ENCEPHALOPATHY (320 patients)
FATIGUE (300 patients)
RASH (276 patients)
ASCITES (253 patients)
ABDOMINAL PAIN (237 patients)
DECREASED APPETITE (226 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (198 patients)
PYREXIA (191 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (179 patients)
NAUSEA (165 patients)
HYPERTENSION (160 patients)
ASTHENIA (154 patients)
DEHYDRATION (140 patients)
HEPATIC FUNCTION ABNORMAL (133 patients)
DYSPNOEA (131 patients)
CONFUSIONAL STATE (131 patients)
HYPOKALAEMIA (125 patients)
ALOPECIA (124 patients)
VOMITING (118 patients)
CONSTIPATION (115 patients)
INTERSTITIAL LUNG DISEASE (114 patients)
LEFT VENTRICULAR DYSFUNCTION (113 patients)
DEATH (113 patients)
ENDOCARDITIS (112 patients)
ARTHRALGIA (111 patients)
STOMATITIS (111 patients)
ABDOMINAL PAIN UPPER (110 patients)
JAUNDICE (108 patients)
HEPATIC NEOPLASM MALIGNANT (106 patients)
GASTROINTESTINAL HAEMORRHAGE (106 patients)
RETINAL VASCULAR THROMBOSIS (103 patients)
LOWER GASTROINTESTINAL HAEMORRHAGE (103 patients)
LIVER CARCINOMA RUPTURED (101 patients)
OEDEMA PERIPHERAL (97 patients)
PLEURAL EFFUSION (97 patients)
STAPHYLOCOCCAL INFECTION (96 patients)
PNEUMONIA BACTERIAL (96 patients)
ENTEROBACTER INFECTION (96 patients)
MYOPATHY (95 patients)
DRY MOUTH (94 patients)
PAIN IN EXTREMITY (93 patients)
ANXIETY (90 patients)
MALAISE (89 patients)
PULMONARY EMBOLISM (85 patients)
ANAEMIA (84 patients)
PLATELET COUNT DECREASED (81 patients)
BACK PAIN (79 patients)
SEPSIS (78 patients)
PRURITUS (78 patients)
DUODENAL ULCER (77 patients)
MIGRAINE (76 patients)
MITRAL VALVE INCOMPETENCE (76 patients)
HYPOGLYCAEMIA (76 patients)
C-REACTIVE PROTEIN INCREASED (74 patients)
BLOOD PRESSURE INCREASED (73 patients)
VARICES OESOPHAGEAL (73 patients)
HEADACHE (72 patients)
RETINAL VEIN OCCLUSION (72 patients)
ABASIA (69 patients)
RENAL FAILURE ACUTE (69 patients)
WEIGHT DECREASED (67 patients)
DEEP VEIN THROMBOSIS (67 patients)
DIZZINESS (65 patients)
ERYTHEMA (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (64 patients)
CONVULSION (63 patients)
ALANINE AMINOTRANSFERASE INCREASED (62 patients)
DYSPHONIA (62 patients)
CEREBRAL HAEMORRHAGE (60 patients)
APHAGIA (58 patients)
COLITIS (58 patients)
PNEUMONIA (57 patients)
GASTRIC ULCER (56 patients)
HYPONATRAEMIA (55 patients)
HAEMOGLOBIN DECREASED (53 patients)
RESPIRATORY FAILURE (52 patients)
LUNG DISORDER (52 patients)
CEREBRAL ISCHAEMIA (49 patients)
PARAESTHESIA (49 patients)
BLOOD BILIRUBIN INCREASED (48 patients)
GAIT DISTURBANCE (48 patients)
THYROID CANCER METASTATIC (44 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (43 patients)
PERICARDIAL EFFUSION (41 patients)
THROMBOCYTOPENIA (41 patients)
BLISTER (41 patients)
FEBRILE NEUTROPENIA (40 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (40 patients)
HALLUCINATION (40 patients)
CHILLS (40 patients)
AMMONIA INCREASED (39 patients)
SKIN ULCER (39 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (38 patients)
PAIN (38 patients)
HYPOALBUMINAEMIA (38 patients)
HYPOCALCAEMIA (37 patients)
FALL (37 patients)
POLLAKIURIA (37 patients)
BLOOD PRESSURE DECREASED (37 patients)
SKIN EXFOLIATION (37 patients)
INSOMNIA (36 patients)
CARDIAC ARREST (36 patients)
HYPOAESTHESIA (35 patients)
INFECTIOUS PERITONITIS (35 patients)
MYOCARDIAL INFARCTION (35 patients)
RETINAL VASCULAR DISORDER (34 patients)
RENAL FAILURE (34 patients)
LIPASE INCREASED (34 patients)
HYPERKALAEMIA (33 patients)
HYPERGLYCAEMIA (33 patients)
HAEMOPTYSIS (31 patients)
ATRIAL FIBRILLATION (30 patients)
GENERALISED OEDEMA (30 patients)
FAECAL INCONTINENCE (30 patients)
WHITE BLOOD CELL COUNT DECREASED (30 patients)
CELLULITIS (29 patients)
CHEST PAIN (29 patients)
SOMNOLENCE (29 patients)
HYPERBILIRUBINAEMIA (28 patients)
HYPOTENSION (28 patients)
MUSCLE SPASMS (28 patients)
ABDOMINAL DISTENSION (27 patients)
WHITE BLOOD CELL COUNT INCREASED (27 patients)
VISION BLURRED (27 patients)
HEPATIC PAIN (26 patients)
BLOOD ALBUMIN DECREASED (26 patients)
DYSURIA (25 patients)
RASH GENERALISED (25 patients)
BLOOD SODIUM DECREASED (25 patients)
BLOOD URIC ACID INCREASED (25 patients)
COMA (25 patients)
COUGH (25 patients)
PANCYTOPENIA (25 patients)
ACUTE ABDOMEN (24 patients)
EOSINOPHIL COUNT INCREASED (24 patients)
CEREBROVASCULAR ACCIDENT (24 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (23 patients)
CEREBRAL INFARCTION (23 patients)
HYPOMAGNESAEMIA (23 patients)
RETINAL VEIN THROMBOSIS (23 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (23 patients)
TUMOUR LYSIS SYNDROME (22 patients)
HYPOPHOSPHATAEMIA (22 patients)
INFECTION (22 patients)
ORAL PAIN (22 patients)
BLOOD CREATININE INCREASED (22 patients)
NEUTROPENIA (22 patients)
RENAL IMPAIRMENT (22 patients)
LETHARGY (22 patients)
SKIN TOXICITY (21 patients)
TONGUE BLISTERING (21 patients)
LIVER ABSCESS (21 patients)
HAEMATEMESIS (21 patients)
OESOPHAGEAL VARICES HAEMORRHAGE (20 patients)
MENTAL IMPAIRMENT (20 patients)
NERVOUSNESS (20 patients)
NEPHROTIC SYNDROME (20 patients)
HYPOPHAGIA (20 patients)
ADRENAL INSUFFICIENCY (19 patients)
DRY SKIN (19 patients)
BLOOD AMYLASE INCREASED (19 patients)
OEDEMA (19 patients)
INFECTIOUS PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
COMA HEPATIC (19 patients)
HEART RATE INCREASED (18 patients)
HYPERTENSIVE CRISIS (18 patients)
MYALGIA (18 patients)
ECZEMA (18 patients)
URINARY TRACT INFECTION (18 patients)
NEUROMYOPATHY (18 patients)
MEDICAL DEVICE COMPLICATION (18 patients)
DIVERTICULITIS (18 patients)
OSTEOMYELITIS (18 patients)
CEREBRAL ATROPHY (18 patients)
CEREBRAL VENTRICLE DILATATION (18 patients)
DIABETIC FOOT INFECTION (18 patients)
NECK PAIN (18 patients)
OLIGURIA (17 patients)
GASTROINTESTINAL DISORDER (17 patients)
HAEMATOCHEZIA (17 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (17 patients)
HYPOTHYROIDISM (17 patients)
TRANSAMINASES INCREASED (17 patients)
OROPHARYNGEAL PAIN (17 patients)
CHRONIC MYELOID LEUKAEMIA (17 patients)
NEOPLASM PROGRESSION (17 patients)
METASTASES TO ADRENALS (16 patients)
LYMPHOCYTE COUNT DECREASED (16 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (16 patients)
MULTI-ORGAN FAILURE (16 patients)
FEAR (16 patients)
PANCREATIC CARCINOMA (16 patients)
HYPERSOMNIA (16 patients)
EPILEPSY (16 patients)
SUBARACHNOID HAEMORRHAGE (16 patients)
METASTASES TO LUNG (16 patients)
TACHYCARDIA (16 patients)
MUSCULAR WEAKNESS (16 patients)
KLEBSIELLA SEPSIS (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
DYSGEUSIA (16 patients)
LUNG INFECTION (16 patients)
FAECES DISCOLOURED (16 patients)
PAIN OF SKIN (16 patients)
SPINAL FRACTURE (16 patients)
PANIC REACTION (16 patients)

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