Is HYPERGLYCAEMIA a side effect of SORAFENIB (RAF KINASE INHIBITOR) ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of SORAFENIB (RAF KINASE INHIBITOR) patients who developed HYPERGLYCAEMIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 33 individuals taking SORAFENIB (RAF KINASE INHIBITOR) reported HYPERGLYCAEMIA to the FDA. A total of 3329 SORAFENIB (RAF KINASE INHIBITOR) drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between SORAFENIB (RAF KINASE INHIBITOR) and HYPERGLYCAEMIA. In doing so, we compare SORAFENIB (RAF KINASE INHIBITOR) with other drugs that cause HYPERGLYCAEMIA, to help you evaluate whether or not SORAFENIB (RAF KINASE INHIBITOR) causes HYPERGLYCAEMIA. Likewise, this page shows the most highly-reported side effects of SORAFENIB (RAF KINASE INHIBITOR), so you can see if HYPERGLYCAEMIA ranks among SORAFENIB (RAF KINASE INHIBITOR)'s most well-known side effects.

Summary Statistics
Reports of SORAFENIB (RAF KINASE INHIBITOR) causing HYPERGLYCAEMIA: 33
Reports of any side effect of SORAFENIB (RAF KINASE INHIBITOR) : 3329
Percentage of SORAFENIB (RAF KINASE INHIBITOR) patients where HYPERGLYCAEMIA is a reported side effect: 0.9913%

FDA reports of any drug causing HYPERGLYCAEMIA : 14689
Average percentage for all medicated patients where HYPERGLYCAEMIA is reported as a complication: 0.0921%

Physician opinion on SORAFENIB (RAF KINASE INHIBITOR) as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing SORAFENIB (RAF KINASE INHIBITOR):

HEPATIC NEOPLASM MALIGNANT ( 770 patients )
RENAL CELL CARCINOMA ( 114 patients )
THYROID CANCER ( 65 patients )
METASTATIC RENAL CELL CARCINOMA ( 44 patients )
THYROID CANCER METASTATIC ( 35 patients )
BREAST CANCER ( 31 patients )
BREAST CANCER METASTATIC ( 27 patients )
GASTRIC CANCER ( 25 patients )
NON-SMALL CELL LUNG CANCER ( 25 patients )
COLORECTAL CANCER METASTATIC ( 22 patients )
RENAL CANCER ( 17 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 14 patients )
BILE DUCT CANCER ( 14 patients )
SALIVARY GLAND CANCER ( 7 patients )
HEPATIC CANCER METASTATIC ( 7 patients )
COLORECTAL CANCER ( 7 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 6 patients )
RECTAL CANCER ( 5 patients )
PANCREATIC CARCINOMA ( 4 patients )
PROSTATE CANCER ( 4 patients )
INTRAOCULAR MELANOMA ( 4 patients )
HEPATIC NEOPLASM MALIGNANT RECURRENT ( 3 patients )
NEOPLASM ( 3 patients )
LIVER DISORDER ( 3 patients )
ANGIOSARCOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 3 patients )
METASTASES TO LUNG ( 3 patients )
HEPATIC NEOPLASM MALIGNANT NON-RESECTABLE ( 3 patients )
COLORECTAL CANCER STAGE IV ( 3 patients )
NEOPLASM MALIGNANT ( 3 patients )
GALLBLADDER CANCER METASTATIC ( 3 patients )
BILIARY CANCER METASTATIC ( 3 patients )
METASTASIS ( 3 patients )
COLON CANCER METASTATIC ( 2 patients )
HYPOPHARYNGEAL CANCER ( 2 patients )
DESMOID TUMOUR ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
ACUTE MYELOID LEUKAEMIA (IN REMISSION) ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
OESOPHAGEAL CARCINOMA ( 2 patients )
METASTATIC MALIGNANT MELANOMA ( 2 patients )
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED ( 2 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 2 patients )
ANGINA PECTORIS ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
OSTEOSARCOMA METASTATIC ( 2 patients )
BONE SARCOMA ( 2 patients )
METASTATIC OCULAR MELANOMA ( 2 patients )
METASTATIC SALIVARY GLAND CANCER ( 2 patients )
TONSIL CANCER ( 2 patients )
MYELODYSPLASTIC SYNDROME ( 1 patients )
PROSTATE CANCER METASTATIC ( 1 patients )
GALLBLADDER CANCER ( 1 patients )
NEUROENDOCRINE TUMOUR ( 1 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 1 patients )
GLIOMA ( 1 patients )
BLADDER CANCER ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
CAROTID ARTERY DISEASE ( 1 patients )
HEPATOBLASTOMA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
ACUTE MYELOID LEUKAEMIA ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
RENAL CANCER METASTATIC ( 1 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 1 patients )
NEUROENDOCRINE CARCINOMA OF THE SKIN ( 1 patients )
MALIGNANT HISTIOCYTOSIS ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 1 patients )
SARCOMA ( 1 patients )
GERM CELL CANCER ( 1 patients )
OESOPHAGEAL ADENOCARCINOMA ( 1 patients )
SQUAMOUS CELL CARCINOMA ( 1 patients )
HEAD AND NECK CANCER ( 1 patients )
OVARIAN EPITHELIAL CANCER ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with HYPERGLYCAEMIA:

SEROQUEL (5930 patients)
LANTUS (2822 patients)
ZYPREXA (2101 patients)
ASPIRIN (1485 patients)
FOSAMAX (1271 patients)
RISPERDAL (966 patients)
HUMALOG (924 patients)
LASIX (922 patients)
HEPARIN SODIUM INJECTION (876 patients)
PREDNISONE (869 patients)
VIOXX (782 patients)
METFORMIN HCL (752 patients)
DEXAMETHASONE (734 patients)
LIPITOR (698 patients)
INSULIN (691 patients)
LISINOPRIL (644 patients)
FUROSEMIDE (562 patients)
AMBIEN (543 patients)
ZOMETA (535 patients)
NEURONTIN (527 patients)
SYNTHROID (502 patients)
SIMVASTATIN (500 patients)
ATENOLOL (484 patients)
NORVASC (462 patients)
ZOCOR (459 patients)
DECADRON (456 patients)
HYDROCHLOROTHIAZIDE (456 patients)
ZOLOFT (451 patients)
PROTONIX (446 patients)
COUMADIN (436 patients)
NEXIUM (428 patients)
XANAX (427 patients)
PAXIL (425 patients)
ABILIFY (419 patients)
GLYBURIDE (415 patients)
PREDNISOLONE (410 patients)
DEPAKOTE (393 patients)
OMEPRAZOLE (386 patients)
ATIVAN (386 patients)
ALBUTEROL (385 patients)
REVLIMID (376 patients)
PRILOSEC (375 patients)
PLAVIX (374 patients)
ACETAMINOPHEN (371 patients)
METHOTREXATE (369 patients)
GLUCOPHAGE (364 patients)
DIGOXIN (363 patients)
LORAZEPAM (357 patients)
AMARYL (351 patients)
NOVOLOG (350 patients)
AREDIA (345 patients)
PROZAC (343 patients)
BYETTA (339 patients)
POTASSIUM CHLORIDE (339 patients)
PREDNISONE TAB (331 patients)
GEODON (329 patients)
LEXAPRO (328 patients)
DIOVAN (321 patients)
ALLOPURINOL (318 patients)
CLONAZEPAM (316 patients)
CELEXA (313 patients)
ACCUTANE (311 patients)
TRAZODONE HCL (306 patients)
METFORMIN (305 patients)
ACTOS (302 patients)
PREVACID (300 patients)
EFFEXOR (292 patients)
CYMBALTA (289 patients)
ZOFRAN (280 patients)
WELLBUTRIN (278 patients)
TOPROL-XL (273 patients)
TEQUIN (273 patients)
AVANDIA (271 patients)
VELCADE (259 patients)
HALDOL (258 patients)
METOPROLOL TARTRATE (258 patients)
OXYCONTIN (257 patients)
LEVOTHYROXINE SODIUM (257 patients)
NOVORAPID (250 patients)
LYRICA (248 patients)
HUMULIN R (247 patients)
IBUPROFEN (243 patients)
GABAPENTIN (241 patients)
CYCLOPHOSPHAMIDE (238 patients)
AFINITOR (234 patients)
ALPRAZOLAM (233 patients)
AMLODIPINE (232 patients)
SPIRONOLACTONE (231 patients)
FOLIC ACID (230 patients)
CISPLATIN (230 patients)
PERCOCET (230 patients)
GLIPIZIDE (228 patients)
SOLOSTAR (228 patients)
COMPAZINE (223 patients)
COREG (220 patients)
CRESTOR (218 patients)
THALIDOMIDE (217 patients)
LEVAQUIN (216 patients)
APIDRA (215 patients)
METHYLPREDNISOLONE (215 patients)
ALTACE (207 patients)
SANDOSTATIN LAR (207 patients)
KLONOPIN (207 patients)
VICODIN (207 patients)
MORPHINE (203 patients)
OXYCODONE HCL (202 patients)
METOPROLOL (199 patients)
DIFLUCAN (198 patients)
ADVAIR DISKUS 100/50 (194 patients)
HUMULIN N (194 patients)
PREMARIN (191 patients)
SOLU-MEDROL (191 patients)
ACYCLOVIR (191 patients)
HUMALOG MIX 75/25 (190 patients)
CLOZARIL (190 patients)
TACROLIMUS (190 patients)
LORTAB (189 patients)
REMERON (189 patients)
LOPRESSOR (188 patients)
COLACE (187 patients)
ENALAPRIL MALEATE (183 patients)
CYCLOSPORINE (182 patients)
RANITIDINE (180 patients)
COZAAR (180 patients)
RAMIPRIL (179 patients)
CELEBREX (179 patients)
SINGULAIR (177 patients)
WARFARIN SODIUM (177 patients)
NITROGLYCERIN (176 patients)
VINCRISTINE (175 patients)
DEXAMETHASONE TAB (174 patients)
ZANTAC (173 patients)
REGLAN (173 patients)
FLEXERIL (171 patients)
VANCOMYCIN (170 patients)
LEVEMIR (170 patients)
PEPCID (169 patients)
CIPROFLOXACIN (169 patients)
LITHIUM CARBONATE (165 patients)
DOCETAXEL (165 patients)
VALIUM (163 patients)
LOVENOX (163 patients)
JANUVIA (162 patients)
ZETIA (159 patients)
CYTARABINE (158 patients)
BENADRYL (158 patients)
TYLENOL (CAPLET) (157 patients)
FAMOTIDINE (154 patients)
BACTRIM (154 patients)
RISPERIDONE (153 patients)
HEPARIN (153 patients)
ALDACTONE (153 patients)
PROGRAF (152 patients)
FLUOROURACIL (149 patients)
AMOXICILLIN (147 patients)
MIRTAZAPINE (147 patients)
LANSOPRAZOLE (147 patients)
EFFEXOR XR (145 patients)
MYCOPHENOLATE MOFETIL (145 patients)
METOCLOPRAMIDE (144 patients)
FLUCONAZOLE (143 patients)
CLONIDINE (143 patients)
OPTICLIK (143 patients)
TRICOR (142 patients)
CARBOPLATIN (142 patients)
ONDANSETRON (141 patients)
MULTI-VITAMINS (141 patients)
THORAZINE (141 patients)
ELAVIL (140 patients)
TOPAMAX (139 patients)
DIANEAL (139 patients)
ZYRTEC (138 patients)
PERIDEX (138 patients)
DIAZEPAM (138 patients)
SODIUM CHLORIDE (136 patients)
NYSTATIN (135 patients)
METFORMIN HYDROCHLORIDE (135 patients)
INSULIN GLARGINE (133 patients)
CARVEDILOL (132 patients)
TYLENOL (132 patients)
HUMULIN 70/30 (130 patients)
RESTORIL (129 patients)
FLONASE (129 patients)
CLINDAMYCIN (129 patients)
REMICADE (128 patients)
ZESTRIL (127 patients)
KEFLEX (126 patients)
NIFEDIPINE (125 patients)
TEMAZEPAM (125 patients)
ALENDRONATE SODIUM (125 patients)
FLAGYL (124 patients)
VITAMIN D (124 patients)
OPTIPEN (INSULIN PUMP) (124 patients)
TRAMADOL HCL (123 patients)
ALL OTHER THERAPEUTIC PRODUCTS (122 patients)
TEGRETOL (122 patients)
NAPROXEN (120 patients)
DILAUDID (120 patients)
FENTANYL (120 patients)
PACLITAXEL (118 patients)
DURAGESIC-100 (117 patients)
AMITRIPTYLINE HCL (117 patients)
RADIATION THERAPY (117 patients)
BEVACIZUMAB (116 patients)
LAMICTAL (116 patients)
MORPHINE SULFATE (114 patients)
GLIMEPIRIDE (114 patients)
GATIFLOXACIN (113 patients)
NOVOLIN R (113 patients)
FLOMAX (113 patients)

Most common side effects for patients taking SORAFENIB (RAF KINASE INHIBITOR):

DIARRHOEA (613 patients)
HEPATIC FAILURE (378 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (342 patients)
HEPATIC ENCEPHALOPATHY (320 patients)
FATIGUE (300 patients)
RASH (276 patients)
ASCITES (253 patients)
ABDOMINAL PAIN (237 patients)
DECREASED APPETITE (226 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (198 patients)
PYREXIA (191 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (179 patients)
NAUSEA (165 patients)
HYPERTENSION (160 patients)
ASTHENIA (154 patients)
DEHYDRATION (140 patients)
HEPATIC FUNCTION ABNORMAL (133 patients)
DYSPNOEA (131 patients)
CONFUSIONAL STATE (131 patients)
HYPOKALAEMIA (125 patients)
ALOPECIA (124 patients)
VOMITING (118 patients)
CONSTIPATION (115 patients)
INTERSTITIAL LUNG DISEASE (114 patients)
LEFT VENTRICULAR DYSFUNCTION (113 patients)
DEATH (113 patients)
ENDOCARDITIS (112 patients)
ARTHRALGIA (111 patients)
STOMATITIS (111 patients)
ABDOMINAL PAIN UPPER (110 patients)
JAUNDICE (108 patients)
HEPATIC NEOPLASM MALIGNANT (106 patients)
GASTROINTESTINAL HAEMORRHAGE (106 patients)
RETINAL VASCULAR THROMBOSIS (103 patients)
LOWER GASTROINTESTINAL HAEMORRHAGE (103 patients)
LIVER CARCINOMA RUPTURED (101 patients)
OEDEMA PERIPHERAL (97 patients)
PLEURAL EFFUSION (97 patients)
STAPHYLOCOCCAL INFECTION (96 patients)
PNEUMONIA BACTERIAL (96 patients)
ENTEROBACTER INFECTION (96 patients)
MYOPATHY (95 patients)
DRY MOUTH (94 patients)
PAIN IN EXTREMITY (93 patients)
ANXIETY (90 patients)
MALAISE (89 patients)
PULMONARY EMBOLISM (85 patients)
ANAEMIA (84 patients)
PLATELET COUNT DECREASED (81 patients)
BACK PAIN (79 patients)
SEPSIS (78 patients)
PRURITUS (78 patients)
DUODENAL ULCER (77 patients)
MIGRAINE (76 patients)
MITRAL VALVE INCOMPETENCE (76 patients)
HYPOGLYCAEMIA (76 patients)
C-REACTIVE PROTEIN INCREASED (74 patients)
BLOOD PRESSURE INCREASED (73 patients)
VARICES OESOPHAGEAL (73 patients)
HEADACHE (72 patients)
RETINAL VEIN OCCLUSION (72 patients)
ABASIA (69 patients)
RENAL FAILURE ACUTE (69 patients)
WEIGHT DECREASED (67 patients)
DEEP VEIN THROMBOSIS (67 patients)
DIZZINESS (65 patients)
ERYTHEMA (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (64 patients)
CONVULSION (63 patients)
ALANINE AMINOTRANSFERASE INCREASED (62 patients)
DYSPHONIA (62 patients)
CEREBRAL HAEMORRHAGE (60 patients)
APHAGIA (58 patients)
COLITIS (58 patients)
PNEUMONIA (57 patients)
GASTRIC ULCER (56 patients)
HYPONATRAEMIA (55 patients)
HAEMOGLOBIN DECREASED (53 patients)
RESPIRATORY FAILURE (52 patients)
LUNG DISORDER (52 patients)
CEREBRAL ISCHAEMIA (49 patients)
PARAESTHESIA (49 patients)
BLOOD BILIRUBIN INCREASED (48 patients)
GAIT DISTURBANCE (48 patients)
THYROID CANCER METASTATIC (44 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (43 patients)
PERICARDIAL EFFUSION (41 patients)
THROMBOCYTOPENIA (41 patients)
BLISTER (41 patients)
FEBRILE NEUTROPENIA (40 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (40 patients)
HALLUCINATION (40 patients)
CHILLS (40 patients)
AMMONIA INCREASED (39 patients)
SKIN ULCER (39 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (38 patients)
PAIN (38 patients)
HYPOALBUMINAEMIA (38 patients)
HYPOCALCAEMIA (37 patients)
FALL (37 patients)
POLLAKIURIA (37 patients)
BLOOD PRESSURE DECREASED (37 patients)
SKIN EXFOLIATION (37 patients)
INSOMNIA (36 patients)
CARDIAC ARREST (36 patients)
HYPOAESTHESIA (35 patients)
INFECTIOUS PERITONITIS (35 patients)
MYOCARDIAL INFARCTION (35 patients)
RETINAL VASCULAR DISORDER (34 patients)
RENAL FAILURE (34 patients)
LIPASE INCREASED (34 patients)
HYPERKALAEMIA (33 patients)
HYPERGLYCAEMIA (33 patients)
HAEMOPTYSIS (31 patients)
ATRIAL FIBRILLATION (30 patients)
GENERALISED OEDEMA (30 patients)
FAECAL INCONTINENCE (30 patients)
WHITE BLOOD CELL COUNT DECREASED (30 patients)
CELLULITIS (29 patients)
CHEST PAIN (29 patients)
SOMNOLENCE (29 patients)
HYPERBILIRUBINAEMIA (28 patients)
HYPOTENSION (28 patients)
MUSCLE SPASMS (28 patients)
ABDOMINAL DISTENSION (27 patients)
WHITE BLOOD CELL COUNT INCREASED (27 patients)
VISION BLURRED (27 patients)
HEPATIC PAIN (26 patients)
BLOOD ALBUMIN DECREASED (26 patients)
DYSURIA (25 patients)
RASH GENERALISED (25 patients)
BLOOD SODIUM DECREASED (25 patients)
BLOOD URIC ACID INCREASED (25 patients)
COMA (25 patients)
COUGH (25 patients)
PANCYTOPENIA (25 patients)
ACUTE ABDOMEN (24 patients)
EOSINOPHIL COUNT INCREASED (24 patients)
CEREBROVASCULAR ACCIDENT (24 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (23 patients)
CEREBRAL INFARCTION (23 patients)
HYPOMAGNESAEMIA (23 patients)
RETINAL VEIN THROMBOSIS (23 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (23 patients)
TUMOUR LYSIS SYNDROME (22 patients)
HYPOPHOSPHATAEMIA (22 patients)
INFECTION (22 patients)
ORAL PAIN (22 patients)
BLOOD CREATININE INCREASED (22 patients)
NEUTROPENIA (22 patients)
RENAL IMPAIRMENT (22 patients)
LETHARGY (22 patients)
SKIN TOXICITY (21 patients)
TONGUE BLISTERING (21 patients)
LIVER ABSCESS (21 patients)
HAEMATEMESIS (21 patients)
OESOPHAGEAL VARICES HAEMORRHAGE (20 patients)
MENTAL IMPAIRMENT (20 patients)
NERVOUSNESS (20 patients)
NEPHROTIC SYNDROME (20 patients)
HYPOPHAGIA (20 patients)
ADRENAL INSUFFICIENCY (19 patients)
DRY SKIN (19 patients)
BLOOD AMYLASE INCREASED (19 patients)
OEDEMA (19 patients)
INFECTIOUS PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
COMA HEPATIC (19 patients)
HEART RATE INCREASED (18 patients)
HYPERTENSIVE CRISIS (18 patients)
MYALGIA (18 patients)
ECZEMA (18 patients)
URINARY TRACT INFECTION (18 patients)
NEUROMYOPATHY (18 patients)
MEDICAL DEVICE COMPLICATION (18 patients)
DIVERTICULITIS (18 patients)
OSTEOMYELITIS (18 patients)
CEREBRAL ATROPHY (18 patients)
CEREBRAL VENTRICLE DILATATION (18 patients)
DIABETIC FOOT INFECTION (18 patients)
NECK PAIN (18 patients)
OLIGURIA (17 patients)
GASTROINTESTINAL DISORDER (17 patients)
HAEMATOCHEZIA (17 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (17 patients)
HYPOTHYROIDISM (17 patients)
TRANSAMINASES INCREASED (17 patients)
OROPHARYNGEAL PAIN (17 patients)
CHRONIC MYELOID LEUKAEMIA (17 patients)
NEOPLASM PROGRESSION (17 patients)
METASTASES TO ADRENALS (16 patients)
LYMPHOCYTE COUNT DECREASED (16 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (16 patients)
MULTI-ORGAN FAILURE (16 patients)
FEAR (16 patients)
PANCREATIC CARCINOMA (16 patients)
HYPERSOMNIA (16 patients)
EPILEPSY (16 patients)
SUBARACHNOID HAEMORRHAGE (16 patients)
METASTASES TO LUNG (16 patients)
TACHYCARDIA (16 patients)
MUSCULAR WEAKNESS (16 patients)
KLEBSIELLA SEPSIS (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
DYSGEUSIA (16 patients)
LUNG INFECTION (16 patients)
FAECES DISCOLOURED (16 patients)
PAIN OF SKIN (16 patients)
SPINAL FRACTURE (16 patients)
PANIC REACTION (16 patients)

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