Is MULTI-ORGAN FAILURE a side effect of SORAFENIB (RAF KINASE INHIBITOR) ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of SORAFENIB (RAF KINASE INHIBITOR) patients who developed MULTI-ORGAN FAILURE.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 16 individuals taking SORAFENIB (RAF KINASE INHIBITOR) reported MULTI-ORGAN FAILURE to the FDA. A total of 3329 SORAFENIB (RAF KINASE INHIBITOR) drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between SORAFENIB (RAF KINASE INHIBITOR) and MULTI-ORGAN FAILURE. In doing so, we compare SORAFENIB (RAF KINASE INHIBITOR) with other drugs that cause MULTI-ORGAN FAILURE, to help you evaluate whether or not SORAFENIB (RAF KINASE INHIBITOR) causes MULTI-ORGAN FAILURE. Likewise, this page shows the most highly-reported side effects of SORAFENIB (RAF KINASE INHIBITOR), so you can see if MULTI-ORGAN FAILURE ranks among SORAFENIB (RAF KINASE INHIBITOR)'s most well-known side effects.

Summary Statistics
Reports of SORAFENIB (RAF KINASE INHIBITOR) causing MULTI-ORGAN FAILURE: 16
Reports of any side effect of SORAFENIB (RAF KINASE INHIBITOR) : 3329
Percentage of SORAFENIB (RAF KINASE INHIBITOR) patients where MULTI-ORGAN FAILURE is a reported side effect: 0.4806%

FDA reports of any drug causing MULTI-ORGAN FAILURE : 21267
Average percentage for all medicated patients where MULTI-ORGAN FAILURE is reported as a complication: 0.1333%

Physician opinion on SORAFENIB (RAF KINASE INHIBITOR) as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing SORAFENIB (RAF KINASE INHIBITOR):

HEPATIC NEOPLASM MALIGNANT ( 770 patients )
RENAL CELL CARCINOMA ( 114 patients )
THYROID CANCER ( 65 patients )
METASTATIC RENAL CELL CARCINOMA ( 44 patients )
THYROID CANCER METASTATIC ( 35 patients )
BREAST CANCER ( 31 patients )
BREAST CANCER METASTATIC ( 27 patients )
GASTRIC CANCER ( 25 patients )
NON-SMALL CELL LUNG CANCER ( 25 patients )
COLORECTAL CANCER METASTATIC ( 22 patients )
RENAL CANCER ( 17 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 14 patients )
BILE DUCT CANCER ( 14 patients )
SALIVARY GLAND CANCER ( 7 patients )
HEPATIC CANCER METASTATIC ( 7 patients )
COLORECTAL CANCER ( 7 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 6 patients )
RECTAL CANCER ( 5 patients )
PANCREATIC CARCINOMA ( 4 patients )
PROSTATE CANCER ( 4 patients )
INTRAOCULAR MELANOMA ( 4 patients )
HEPATIC NEOPLASM MALIGNANT RECURRENT ( 3 patients )
NEOPLASM ( 3 patients )
LIVER DISORDER ( 3 patients )
ANGIOSARCOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 3 patients )
METASTASES TO LUNG ( 3 patients )
HEPATIC NEOPLASM MALIGNANT NON-RESECTABLE ( 3 patients )
COLORECTAL CANCER STAGE IV ( 3 patients )
NEOPLASM MALIGNANT ( 3 patients )
GALLBLADDER CANCER METASTATIC ( 3 patients )
BILIARY CANCER METASTATIC ( 3 patients )
METASTASIS ( 3 patients )
COLON CANCER METASTATIC ( 2 patients )
HYPOPHARYNGEAL CANCER ( 2 patients )
DESMOID TUMOUR ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
ACUTE MYELOID LEUKAEMIA (IN REMISSION) ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
OESOPHAGEAL CARCINOMA ( 2 patients )
METASTATIC MALIGNANT MELANOMA ( 2 patients )
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED ( 2 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 2 patients )
ANGINA PECTORIS ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
OSTEOSARCOMA METASTATIC ( 2 patients )
BONE SARCOMA ( 2 patients )
METASTATIC OCULAR MELANOMA ( 2 patients )
METASTATIC SALIVARY GLAND CANCER ( 2 patients )
TONSIL CANCER ( 2 patients )
MYELODYSPLASTIC SYNDROME ( 1 patients )
PROSTATE CANCER METASTATIC ( 1 patients )
GALLBLADDER CANCER ( 1 patients )
NEUROENDOCRINE TUMOUR ( 1 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 1 patients )
GLIOMA ( 1 patients )
BLADDER CANCER ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
CAROTID ARTERY DISEASE ( 1 patients )
HEPATOBLASTOMA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
ACUTE MYELOID LEUKAEMIA ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
RENAL CANCER METASTATIC ( 1 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 1 patients )
NEUROENDOCRINE CARCINOMA OF THE SKIN ( 1 patients )
MALIGNANT HISTIOCYTOSIS ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 1 patients )
SARCOMA ( 1 patients )
GERM CELL CANCER ( 1 patients )
OESOPHAGEAL ADENOCARCINOMA ( 1 patients )
SQUAMOUS CELL CARCINOMA ( 1 patients )
HEAD AND NECK CANCER ( 1 patients )
OVARIAN EPITHELIAL CANCER ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with MULTI-ORGAN FAILURE:

TRASYLOL (6225 patients)
HEPARIN SODIUM INJECTION (2581 patients)
HEPARIN (1979 patients)
LASIX (1912 patients)
ASPIRIN (1509 patients)
VANCOMYCIN (1194 patients)
PREDNISOLONE (1144 patients)
METHOTREXATE (1019 patients)
NITROGLYCERIN (928 patients)
PROTAMINE SULFATE (869 patients)
ACETAMINOPHEN (842 patients)
FUROSEMIDE (839 patients)
CYCLOPHOSPHAMIDE (834 patients)
PREDNISONE (828 patients)
INSULIN (770 patients)
RED BLOOD CELLS (759 patients)
FENTANYL (758 patients)
ACETYLSALICYLIC ACID SRT (734 patients)
CYCLOSPORINE (723 patients)
REMICADE (710 patients)
LISINOPRIL (693 patients)
LIPITOR (666 patients)
DIGOXIN (654 patients)
VERSED (650 patients)
OMEPRAZOLE (649 patients)
HEPARIN SODIUM (638 patients)
PLAVIX (611 patients)
ALLOPURINOL (573 patients)
PLATELETS (557 patients)
TACROLIMUS (555 patients)
CYTARABINE (551 patients)
ATENOLOL (537 patients)
POTASSIUM CHLORIDE (531 patients)
DOPAMINE HCL (525 patients)
DEXAMETHASONE (514 patients)
SOLU-MEDROL (508 patients)
EPINEPHRINE (490 patients)
HUMIRA (490 patients)
COUMADIN (488 patients)
AMIODARONE HCL (480 patients)
MYCOPHENOLATE MOFETIL (471 patients)
MANNITOL (457 patients)
METHYLPREDNISOLONE (438 patients)
FOLIC ACID (435 patients)
PROPOFOL (434 patients)
SIMVASTATIN (433 patients)
FLUCONAZOLE (432 patients)
NORVASC (432 patients)
MORPHINE (425 patients)
LIDOCAINE (396 patients)
ZOCOR (394 patients)
REVLIMID (388 patients)
FLUOROURACIL (381 patients)
PROGRAF (378 patients)
HYDROCHLOROTHIAZIDE (372 patients)
PREDNISONE TAB (371 patients)
ALBUMIN (HUMAN) (370 patients)
METFORMIN HCL (369 patients)
FRESH FROZEN PLASMA (361 patients)
METOPROLOL TARTRATE (357 patients)
ANCEF (347 patients)
LOPRESSOR (343 patients)
ACYCLOVIR (341 patients)
NEXIUM (341 patients)
TOPROL-XL (331 patients)
LEVOTHYROXINE SODIUM (321 patients)
CIPROFLOXACIN (318 patients)
LOVENOX (315 patients)
PROTONIX (314 patients)
SODIUM BICARBONATE (311 patients)
FLUDARABINE PHOSPHATE (309 patients)
ETOPOSIDE (308 patients)
MEROPENEM (299 patients)
MIDAZOLAM HCL (298 patients)
DIOVAN (296 patients)
WARFARIN SODIUM (291 patients)
COREG (289 patients)
NEORAL (288 patients)
ALDACTONE (288 patients)
FAMOTIDINE (287 patients)
LEVOPHED (286 patients)
MILRINONE (285 patients)
THYMOGLOBULIN (285 patients)
IBUPROFEN (278 patients)
CISPLATIN (272 patients)
MAGNESIUM SULFATE (269 patients)
RITUXIMAB (264 patients)
ENBREL (261 patients)
AMLODIPINE (259 patients)
RAMIPRIL (258 patients)
LANSOPRAZOLE (258 patients)
LEVAQUIN (255 patients)
VELCADE (252 patients)
SPIRONOLACTONE (250 patients)
CALCIUM CHLORIDE (247 patients)
LORAZEPAM (242 patients)
EXJADE (242 patients)
ALBUTEROL (241 patients)
HYDROCORTISONE (239 patients)
ATIVAN (237 patients)
DOXORUBICIN HCL (233 patients)
HEPARIN SODIUM 5,000 UNITS IN DEXTROSE 5% (232 patients)
NOVOSEVEN (231 patients)
DIFLUCAN (231 patients)
SYNTHROID (230 patients)
XIGRIS (228 patients)
CEFAZOLIN (227 patients)
ZOFRAN (227 patients)
CELLCEPT (226 patients)
PANTOPRAZOLE (225 patients)
NEUPOGEN (222 patients)
ENALAPRIL MALEATE (217 patients)
GENTAMICIN (215 patients)
METOPROLOL (213 patients)
VINCRISTINE (212 patients)
VIOXX (210 patients)
DECADRON (206 patients)
DOBUTAMINE HCL (200 patients)
TRAMADOL HCL (198 patients)
BACTRIM (198 patients)
FLUDARA (197 patients)
VOLTAREN (197 patients)
AMIODARONE (197 patients)
PREDONINE (193 patients)
SEROQUEL (193 patients)
PARACETAMOL (192 patients)
DIANEAL (192 patients)
OXALIPLATIN (191 patients)
CARBOPLATIN (191 patients)
AMOXICILLIN (185 patients)
PANTOPRAZOLE SODIUM (185 patients)
ZOSYN (184 patients)
XANAX (184 patients)
PHENYLEPHRINE HCL (184 patients)
LANTUS (184 patients)
AMPHOTERICIN B (184 patients)
PLASMA (182 patients)
AMBISOME (182 patients)
NEURONTIN (182 patients)
ZANTAC (182 patients)
VORICONAZOLE (182 patients)
COLCHICINE (182 patients)
AMICAR (182 patients)
GLEEVEC (181 patients)
METRONIDAZOLE (181 patients)
PRILOSEC (181 patients)
LEVOFLOXACIN (180 patients)
BENADRYL (179 patients)
CLONIDINE (178 patients)
OXYCONTIN (178 patients)
METOCLOPRAMIDE (178 patients)
MELPHALAN (178 patients)
TRACLEER (178 patients)
COZAAR (177 patients)
ROCEPHIN (176 patients)
PEPCID (174 patients)
CANCIDAS (172 patients)
NOREPINEPHRINE BITARTRATE (170 patients)
ONDANSETRON (170 patients)
CRESTOR (170 patients)
SANDIMMUNE (169 patients)
CAMPATH (169 patients)
DIAZEPAM (167 patients)
INFLIXIMAB (167 patients)
CLARITHROMYCIN (166 patients)
PREVACID (166 patients)
ZOMETA (165 patients)
FERROUS SULFATE TAB (165 patients)
RANITIDINE (163 patients)
AZATHIOPRINE (162 patients)
GLYBURIDE (161 patients)
TORSEMIDE (160 patients)
AVANDIA (160 patients)
VICODIN (159 patients)
IMDUR (158 patients)
CALCIUM CARBONATE (158 patients)
NIFEDIPINE (158 patients)
CARVEDILOL (158 patients)
GLIPIZIDE (157 patients)
DOCETAXEL (157 patients)
CEFEPIME (155 patients)
OXYCODONE HCL (155 patients)
PAXIL (155 patients)
ALPRAZOLAM (154 patients)
SOLIRIS (154 patients)
AMBIEN (154 patients)
SODIUM CHLORIDE (152 patients)
GLUCOPHAGE (152 patients)
CORDARONE (151 patients)
ZYVOX (149 patients)
CEFUROXIME (149 patients)
AVASTIN (148 patients)
METOPROLOL SUCCINATE (147 patients)
MIDAZOLAM (146 patients)
CELEBREX (146 patients)
CAPTOPRIL (144 patients)
PRADAXA (143 patients)
VASOPRESSIN (142 patients)
DEXAMETHASONE TAB (142 patients)
FLAGYL (142 patients)
PAVULON (141 patients)
RISPERDAL (141 patients)
LEUCOVORIN CALCIUM (141 patients)
VECURONIUM BROMIDE (141 patients)
ATORVASTATIN CALCIUM (140 patients)
DICLOFENAC SODIUM (139 patients)
SUTENT (137 patients)
LACTULOSE (137 patients)
PRIMAXIN (137 patients)
BISOPROLOL FUMARATE (137 patients)

Most common side effects for patients taking SORAFENIB (RAF KINASE INHIBITOR):

DIARRHOEA (613 patients)
HEPATIC FAILURE (378 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (342 patients)
HEPATIC ENCEPHALOPATHY (320 patients)
FATIGUE (300 patients)
RASH (276 patients)
ASCITES (253 patients)
ABDOMINAL PAIN (237 patients)
DECREASED APPETITE (226 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (198 patients)
PYREXIA (191 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (179 patients)
NAUSEA (165 patients)
HYPERTENSION (160 patients)
ASTHENIA (154 patients)
DEHYDRATION (140 patients)
HEPATIC FUNCTION ABNORMAL (133 patients)
DYSPNOEA (131 patients)
CONFUSIONAL STATE (131 patients)
HYPOKALAEMIA (125 patients)
ALOPECIA (124 patients)
VOMITING (118 patients)
CONSTIPATION (115 patients)
INTERSTITIAL LUNG DISEASE (114 patients)
LEFT VENTRICULAR DYSFUNCTION (113 patients)
DEATH (113 patients)
ENDOCARDITIS (112 patients)
ARTHRALGIA (111 patients)
STOMATITIS (111 patients)
ABDOMINAL PAIN UPPER (110 patients)
JAUNDICE (108 patients)
HEPATIC NEOPLASM MALIGNANT (106 patients)
GASTROINTESTINAL HAEMORRHAGE (106 patients)
RETINAL VASCULAR THROMBOSIS (103 patients)
LOWER GASTROINTESTINAL HAEMORRHAGE (103 patients)
LIVER CARCINOMA RUPTURED (101 patients)
OEDEMA PERIPHERAL (97 patients)
PLEURAL EFFUSION (97 patients)
STAPHYLOCOCCAL INFECTION (96 patients)
PNEUMONIA BACTERIAL (96 patients)
ENTEROBACTER INFECTION (96 patients)
MYOPATHY (95 patients)
DRY MOUTH (94 patients)
PAIN IN EXTREMITY (93 patients)
ANXIETY (90 patients)
MALAISE (89 patients)
PULMONARY EMBOLISM (85 patients)
ANAEMIA (84 patients)
PLATELET COUNT DECREASED (81 patients)
BACK PAIN (79 patients)
SEPSIS (78 patients)
PRURITUS (78 patients)
DUODENAL ULCER (77 patients)
MIGRAINE (76 patients)
MITRAL VALVE INCOMPETENCE (76 patients)
HYPOGLYCAEMIA (76 patients)
C-REACTIVE PROTEIN INCREASED (74 patients)
BLOOD PRESSURE INCREASED (73 patients)
VARICES OESOPHAGEAL (73 patients)
HEADACHE (72 patients)
RETINAL VEIN OCCLUSION (72 patients)
ABASIA (69 patients)
RENAL FAILURE ACUTE (69 patients)
WEIGHT DECREASED (67 patients)
DEEP VEIN THROMBOSIS (67 patients)
DIZZINESS (65 patients)
ERYTHEMA (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (64 patients)
CONVULSION (63 patients)
ALANINE AMINOTRANSFERASE INCREASED (62 patients)
DYSPHONIA (62 patients)
CEREBRAL HAEMORRHAGE (60 patients)
APHAGIA (58 patients)
COLITIS (58 patients)
PNEUMONIA (57 patients)
GASTRIC ULCER (56 patients)
HYPONATRAEMIA (55 patients)
HAEMOGLOBIN DECREASED (53 patients)
RESPIRATORY FAILURE (52 patients)
LUNG DISORDER (52 patients)
CEREBRAL ISCHAEMIA (49 patients)
PARAESTHESIA (49 patients)
BLOOD BILIRUBIN INCREASED (48 patients)
GAIT DISTURBANCE (48 patients)
THYROID CANCER METASTATIC (44 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (43 patients)
PERICARDIAL EFFUSION (41 patients)
THROMBOCYTOPENIA (41 patients)
BLISTER (41 patients)
FEBRILE NEUTROPENIA (40 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (40 patients)
HALLUCINATION (40 patients)
CHILLS (40 patients)
AMMONIA INCREASED (39 patients)
SKIN ULCER (39 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (38 patients)
PAIN (38 patients)
HYPOALBUMINAEMIA (38 patients)
HYPOCALCAEMIA (37 patients)
FALL (37 patients)
POLLAKIURIA (37 patients)
BLOOD PRESSURE DECREASED (37 patients)
SKIN EXFOLIATION (37 patients)
INSOMNIA (36 patients)
CARDIAC ARREST (36 patients)
HYPOAESTHESIA (35 patients)
INFECTIOUS PERITONITIS (35 patients)
MYOCARDIAL INFARCTION (35 patients)
RETINAL VASCULAR DISORDER (34 patients)
RENAL FAILURE (34 patients)
LIPASE INCREASED (34 patients)
HYPERKALAEMIA (33 patients)
HYPERGLYCAEMIA (33 patients)
HAEMOPTYSIS (31 patients)
ATRIAL FIBRILLATION (30 patients)
GENERALISED OEDEMA (30 patients)
FAECAL INCONTINENCE (30 patients)
WHITE BLOOD CELL COUNT DECREASED (30 patients)
CELLULITIS (29 patients)
CHEST PAIN (29 patients)
SOMNOLENCE (29 patients)
HYPERBILIRUBINAEMIA (28 patients)
HYPOTENSION (28 patients)
MUSCLE SPASMS (28 patients)
ABDOMINAL DISTENSION (27 patients)
WHITE BLOOD CELL COUNT INCREASED (27 patients)
VISION BLURRED (27 patients)
HEPATIC PAIN (26 patients)
BLOOD ALBUMIN DECREASED (26 patients)
DYSURIA (25 patients)
RASH GENERALISED (25 patients)
BLOOD SODIUM DECREASED (25 patients)
BLOOD URIC ACID INCREASED (25 patients)
COMA (25 patients)
COUGH (25 patients)
PANCYTOPENIA (25 patients)
ACUTE ABDOMEN (24 patients)
EOSINOPHIL COUNT INCREASED (24 patients)
CEREBROVASCULAR ACCIDENT (24 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (23 patients)
CEREBRAL INFARCTION (23 patients)
HYPOMAGNESAEMIA (23 patients)
RETINAL VEIN THROMBOSIS (23 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (23 patients)
TUMOUR LYSIS SYNDROME (22 patients)
HYPOPHOSPHATAEMIA (22 patients)
INFECTION (22 patients)
ORAL PAIN (22 patients)
BLOOD CREATININE INCREASED (22 patients)
NEUTROPENIA (22 patients)
RENAL IMPAIRMENT (22 patients)
LETHARGY (22 patients)
SKIN TOXICITY (21 patients)
TONGUE BLISTERING (21 patients)
LIVER ABSCESS (21 patients)
HAEMATEMESIS (21 patients)
OESOPHAGEAL VARICES HAEMORRHAGE (20 patients)
MENTAL IMPAIRMENT (20 patients)
NERVOUSNESS (20 patients)
NEPHROTIC SYNDROME (20 patients)
HYPOPHAGIA (20 patients)
ADRENAL INSUFFICIENCY (19 patients)
DRY SKIN (19 patients)
BLOOD AMYLASE INCREASED (19 patients)
OEDEMA (19 patients)
INFECTIOUS PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
COMA HEPATIC (19 patients)
HEART RATE INCREASED (18 patients)
HYPERTENSIVE CRISIS (18 patients)
MYALGIA (18 patients)
ECZEMA (18 patients)
URINARY TRACT INFECTION (18 patients)
NEUROMYOPATHY (18 patients)
MEDICAL DEVICE COMPLICATION (18 patients)
DIVERTICULITIS (18 patients)
OSTEOMYELITIS (18 patients)
CEREBRAL ATROPHY (18 patients)
CEREBRAL VENTRICLE DILATATION (18 patients)
DIABETIC FOOT INFECTION (18 patients)
NECK PAIN (18 patients)
OLIGURIA (17 patients)
GASTROINTESTINAL DISORDER (17 patients)
HAEMATOCHEZIA (17 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (17 patients)
HYPOTHYROIDISM (17 patients)
TRANSAMINASES INCREASED (17 patients)
OROPHARYNGEAL PAIN (17 patients)
CHRONIC MYELOID LEUKAEMIA (17 patients)
NEOPLASM PROGRESSION (17 patients)
METASTASES TO ADRENALS (16 patients)
LYMPHOCYTE COUNT DECREASED (16 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (16 patients)
MULTI-ORGAN FAILURE (16 patients)
FEAR (16 patients)
PANCREATIC CARCINOMA (16 patients)
HYPERSOMNIA (16 patients)
EPILEPSY (16 patients)
SUBARACHNOID HAEMORRHAGE (16 patients)
METASTASES TO LUNG (16 patients)
TACHYCARDIA (16 patients)
MUSCULAR WEAKNESS (16 patients)
KLEBSIELLA SEPSIS (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
DYSGEUSIA (16 patients)
LUNG INFECTION (16 patients)
FAECES DISCOLOURED (16 patients)
PAIN OF SKIN (16 patients)
SPINAL FRACTURE (16 patients)
PANIC REACTION (16 patients)

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