Is myopathy a side effect of TOPROL-XL ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of TOPROL-XL patients who developed myopathy.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 49 individuals taking TOPROL-XL reported myopathy to the FDA. A total of 34685 TOPROL-XL drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between TOPROL-XL and myopathy. In doing so, we compare TOPROL-XL with other drugs that cause myopathy, to help you evaluate whether or not TOPROL-XL causes myopathy. Likewise, this page shows the most highly-reported side effects of TOPROL-XL, so you can see if myopathy ranks among TOPROL-XL's most well-known side effects.

Summary Statistics
Reports of TOPROL-XL causing myopathy: 49
Reports of any side effect of TOPROL-XL : 34685
Percentage of TOPROL-XL patients where myopathy is a reported side effect: 0.1413%

FDA reports of any drug causing myopathy : 3605
Average percentage for all medicated patients where myopathy is reported as a complication: 0.0226%

Physician opinion on TOPROL-XL as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing TOPROL-XL:

HYPERTENSION ( 3638 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 986 patients )
DRUG USE FOR UNKNOWN INDICATION ( 890 patients )
BLOOD PRESSURE ( 436 patients )
CARDIAC DISORDER ( 381 patients )
ATRIAL FIBRILLATION ( 265 patients )
BLOOD PRESSURE INCREASED ( 92 patients )
CORONARY ARTERY DISEASE ( 90 patients )
BLOOD PRESSURE ABNORMAL ( 84 patients )
ARRHYTHMIA ( 82 patients )
TACHYCARDIA ( 80 patients )
HEART RATE INCREASED ( 76 patients )
HEART RATE IRREGULAR ( 70 patients )
PALPITATIONS ( 66 patients )
ANGINA PECTORIS ( 61 patients )
SUPRAVENTRICULAR TACHYCARDIA ( 51 patients )
CARDIAC FAILURE CONGESTIVE ( 51 patients )
MYOCARDIAL INFARCTION ( 44 patients )
MITRAL VALVE PROLAPSE ( 31 patients )
ILL-DEFINED DISORDER ( 30 patients )
HEART RATE ABNORMAL ( 30 patients )
PROPHYLAXIS ( 24 patients )
CARDIAC FAILURE ( 24 patients )
HEART RATE ( 22 patients )
MIGRAINE ( 18 patients )
VENTRICULAR EXTRASYSTOLES ( 17 patients )
BLOOD PRESSURE MANAGEMENT ( 15 patients )
ANXIETY ( 14 patients )
CARDIOMYOPATHY ( 13 patients )
CHEST PAIN ( 12 patients )
MIGRAINE PROPHYLAXIS ( 10 patients )
CARDIOVASCULAR DISORDER ( 9 patients )
ESSENTIAL HYPERTENSION ( 9 patients )
BLOOD CHOLESTEROL INCREASED ( 9 patients )
VASCULAR GRAFT ( 9 patients )
SUPRAVENTRICULAR EXTRASYSTOLES ( 8 patients )
SINUS TACHYCARDIA ( 8 patients )
CORONARY ARTERY BYPASS ( 7 patients )
EXTRASYSTOLES ( 6 patients )
CARDIAC MURMUR ( 6 patients )
FLUSHING ( 6 patients )
PARKINSON'S DISEASE ( 5 patients )
VENTRICULAR TACHYCARDIA ( 5 patients )
ACUTE CORONARY SYNDROME ( 5 patients )
CORONARY ARTERIAL STENT INSERTION ( 5 patients )
ARRHYTHMIA SUPRAVENTRICULAR ( 4 patients )
CARDIAC OPERATION ( 4 patients )
ANTICOAGULANT THERAPY ( 4 patients )
TREMOR ( 4 patients )
POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME ( 4 patients )
HYPOTHYROIDISM ( 4 patients )
ISCHAEMIC HEART DISEASE PROPHYLAXIS ( 3 patients )
STENT PLACEMENT ( 3 patients )
SYNCOPE ( 3 patients )
HYPOTENSION ( 3 patients )
RENAL DISORDER ( 3 patients )
BLOOD PRESSURE DIASTOLIC INCREASED ( 3 patients )
TACHYARRHYTHMIA ( 3 patients )
CHEST DISCOMFORT ( 3 patients )
PULSE ABNORMAL ( 3 patients )
BLOOD CHOLESTEROL ( 3 patients )
CARDIAC FLUTTER ( 3 patients )
HEART RATE DECREASED ( 2 patients )
WEIGHT CONTROL ( 2 patients )
ADRENAL DISORDER ( 2 patients )
HEPATIC CIRRHOSIS ( 2 patients )
MITRAL VALVE DISEASE ( 2 patients )
ATRIAL TACHYCARDIA ( 2 patients )
HYPERSENSITIVITY ( 2 patients )
CARDIAC FAILURE CHRONIC ( 2 patients )
BICUSPID AORTIC VALVE ( 2 patients )
CARDIAC FIBRILLATION ( 2 patients )
GASTROOESOPHAGEAL REFLUX DISEASE ( 2 patients )
CORONARY ARTERY OCCLUSION ( 2 patients )
HEADACHE ( 2 patients )
DIABETES MELLITUS ( 2 patients )
ARTERIAL DISORDER ( 2 patients )
CARDIAC PACEMAKER INSERTION ( 2 patients )
PAIN PROPHYLAXIS ( 2 patients )
ARTERIOSCLEROSIS ( 2 patients )
PANIC ATTACK ( 2 patients )
BLOOD PRESSURE INADEQUATELY CONTROLLED ( 2 patients )
LOSS OF CONSCIOUSNESS ( 2 patients )
HYPERCHOLESTEROLAEMIA ( 2 patients )
ANGINA UNSTABLE ( 2 patients )
CARDIAC ABLATION ( 2 patients )
MITRAL VALVE INCOMPETENCE ( 2 patients )
THROMBOSIS ( 2 patients )
TRANSIENT ISCHAEMIC ATTACK ( 2 patients )
AORTIC DISORDER ( 2 patients )
AORTIC VALVE STENOSIS ( 2 patients )
BLOOD DISORDER ( 1 patients )
DEPRESSION ( 1 patients )
PAIN ( 1 patients )
VENTRICULAR HYPOKINESIA ( 1 patients )
DRESSLER'S SYNDROME ( 1 patients )
LEFT VENTRICULAR DYSFUNCTION ( 1 patients )
ARTERIAL STENT INSERTION ( 1 patients )
CARDIOMEGALY ( 1 patients )
BLOOD PRESSURE FLUCTUATION ( 1 patients )
DRUG THERAPY CHANGED ( 1 patients )
LONG QT SYNDROME ( 1 patients )
ARTERIOSCLEROSIS CORONARY ARTERY ( 1 patients )
DYSPNOEA ( 1 patients )
SYSTOLIC HYPERTENSION ( 1 patients )
CEREBROVASCULAR ACCIDENT ( 1 patients )
BRAIN OPERATION ( 1 patients )
PULMONARY OEDEMA ( 1 patients )
THROMBOSIS PROPHYLAXIS ( 1 patients )
AUTONOMIC NEUROPATHY ( 1 patients )
CONGESTIVE CARDIOMYOPATHY ( 1 patients )
AORTIC ANEURYSM ( 1 patients )
FLUID RETENTION ( 1 patients )
SARCOMA ( 1 patients )
AORTIC VALVE REPLACEMENT ( 1 patients )
NERVOUSNESS ( 1 patients )
VENOUS THROMBOSIS ( 1 patients )
ISCHAEMIC CARDIOMYOPATHY ( 1 patients )
ORTHOSTATIC HYPOTENSION ( 1 patients )
VENTRICULAR FIBRILLATION ( 1 patients )
LABILE HYPERTENSION ( 1 patients )
STRESS ( 1 patients )
DRUG THERAPY ( 1 patients )
LEUKOCYTE ANTIGEN B-27 POSITIVE ( 1 patients )
WOLFF-PARKINSON-WHITE SYNDROME ( 1 patients )
SYNCOPE VASOVAGAL ( 1 patients )
ASTHMA ( 1 patients )
CARDIOVASCULAR EVENT PROPHYLAXIS ( 1 patients )
HEART VALVE INCOMPETENCE ( 1 patients )
ANEURYSM ( 1 patients )
EJECTION FRACTION DECREASED ( 1 patients )
ATRIAL FLUTTER ( 1 patients )
ESSENTIAL TREMOR ( 1 patients )
AUTONOMIC NERVOUS SYSTEM IMBALANCE ( 1 patients )
CHRONIC OBSTRUCTIVE PULMONARY DISEASE ( 1 patients )
FLUID OVERLOAD ( 1 patients )
MUSCULOSKELETAL PAIN ( 1 patients )
BASEDOW'S DISEASE ( 1 patients )
RENAL HYPERTENSION ( 1 patients )
MYOCARDIAL ISCHAEMIA ( 1 patients )
INVESTIGATION ( 1 patients )
SICK SINUS SYNDROME ( 1 patients )
GLAUCOMA ( 1 patients )
OEDEMA PERIPHERAL ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with myopathy:

LIPITOR (517 patients)
ZOCOR (480 patients)
ASPIRIN (474 patients)
SIMVASTATIN (410 patients)
FOSAMAX (309 patients)
PREDNISONE (241 patients)
CRESTOR (239 patients)
ZOMETA (201 patients)
PREDNISOLONE (199 patients)
LASIX (177 patients)
FUROSEMIDE (162 patients)
ZETIA (153 patients)
HYDROCHLOROTHIAZIDE (144 patients)
PREDNISONE TAB (139 patients)
LEVOTHYROXINE SODIUM (138 patients)
VIOXX (130 patients)
ALLOPURINOL (125 patients)
DEXAMETHASONE (124 patients)
INSULIN (120 patients)
COUMADIN (118 patients)
CYCLOSPORINE (113 patients)
ATENOLOL (112 patients)
ATORVASTATIN CALCIUM (110 patients)
NORVASC (108 patients)
CLARITHROMYCIN (107 patients)
AMBIEN (104 patients)
MYCOPHENOLATE MOFETIL (103 patients)
LISINOPRIL (99 patients)
NOROXIN (98 patients)
DECADRON (97 patients)
OMEPRAZOLE (97 patients)
POTASSIUM CHLORIDE (96 patients)
SORAFENIB (RAF KINASE INHIBITOR) (95 patients)
GABAPENTIN (94 patients)
SYNTHROID (94 patients)
LAMIVUDINE (90 patients)
AMLODIPINE (90 patients)
RAMIPRIL (89 patients)
NEXIUM (88 patients)
PRILOSEC (87 patients)
METHYLPREDNISOLONE (85 patients)
WARFARIN SODIUM (83 patients)
ZIDOVUDINE (82 patients)
ALBUTEROL (82 patients)
LANSOPRAZOLE (80 patients)
MEK INHIBITOR (DIHYDROXYPROP-DIFLU-METHOXYPHEN-CYCLOPROPA-SULFAMI) (80 patients)
PROTONIX (79 patients)
ACETAMINOPHEN (77 patients)
FOLIC ACID (77 patients)
MULTI-VITAMINS (75 patients)
XANAX (75 patients)
COZAAR (73 patients)
NEURONTIN (73 patients)
REMICADE (71 patients)
REVLIMID (69 patients)
HUMIRA (68 patients)
AMIODARONE HCL (67 patients)
FLONASE (65 patients)
CELEXA (64 patients)
FERROUS SULFATE TAB (64 patients)
ATORVASTATIN (64 patients)
AMLODIPINE BESYLATE (64 patients)
SPIRONOLACTONE (63 patients)
MAGNEVIST (62 patients)
VYTORIN (62 patients)
ZOLOFT (61 patients)
PEPCID (60 patients)
PROGRAF (60 patients)
CITALOPRAM HYDROBROMIDE (59 patients)
VICODIN (59 patients)
ADVAIR DISKUS 100/50 (59 patients)
ULTRAVIST 150 (59 patients)
PLAVIX (59 patients)
METHOTREXATE (58 patients)
COLCHICINE (58 patients)
AREDIA (57 patients)
OXYCONTIN (57 patients)
LYRICA (57 patients)
DIDANOSINE (56 patients)
ENALAPRIL MALEATE (55 patients)
HEPARIN SODIUM INJECTION (55 patients)
TAMOXIFEN CITRATE (55 patients)
ACYCLOVIR (52 patients)
FENOFIBRATE (52 patients)
PRAVASTATIN (52 patients)
CLONAZEPAM (51 patients)
ITRACONAZOLE (51 patients)
CYCLOPHOSPHAMIDE (51 patients)
DIGOXIN (49 patients)
SEBIVO (49 patients)
TOPROL-XL (49 patients)
LORAZEPAM (48 patients)
DILTIAZEM (48 patients)
LORTAB (48 patients)
ELAVIL (47 patients)
DIFLUCAN (47 patients)
METOPROLOL TARTRATE (46 patients)
ATIVAN (46 patients)
VELCADE (45 patients)
ALENDRONATE SODIUM (45 patients)
VITAMIN D (45 patients)
KLOR-CON (45 patients)
PRAVACHOL (45 patients)
WELLBUTRIN (44 patients)
TRICOR (44 patients)
DARVOCET-N 100 (44 patients)
PERCOCET (44 patients)
RAPAMUNE (43 patients)
ASCORBIC ACID (43 patients)
LEVAQUIN (43 patients)
AROMASIN (43 patients)
DIAZEPAM (43 patients)
ZANTAC (43 patients)
GEMFIBROZIL (41 patients)
CELEBREX (41 patients)
OXYCODONE HCL (41 patients)
ABACAVIR (40 patients)
LEXAPRO (40 patients)
NIFEDIPINE (40 patients)
RADIATION THERAPY (39 patients)
ACETYLSALICYLIC ACID SRT (39 patients)
ACIPHEX (39 patients)
METFORMIN HCL (39 patients)
IRON (39 patients)
ALTACE (39 patients)
TACROLIMUS (38 patients)
EFAVIRENZ (38 patients)
ZYPREXA (38 patients)
ZYRTEC (38 patients)
LESCOL (37 patients)
[THERAPY UNSPECIFIED] (37 patients)
METOPROLOL (37 patients)
GLEEVEC (37 patients)
PANTOPRAZOLE SODIUM (36 patients)
FOSAMAX PLUS D (36 patients)
PROPRANOLOL HYDROCHLORIDE (36 patients)
EFFEXOR (36 patients)
AMIODARONE (36 patients)
CEFTRIAXONE (36 patients)
HERCEPTIN (35 patients)
THALIDOMIDE (35 patients)
FUSIDIC ACID (35 patients)
SINGULAIR (35 patients)
IBUPROFEN (35 patients)
SPIRIVA (35 patients)
LOSARTAN POTASSIUM (35 patients)
VANCOMYCIN (35 patients)
WARFARIN (34 patients)
PERIDEX (34 patients)
BISOPROLOL (34 patients)
HYZAAR (34 patients)
SIROLIMUS (34 patients)
SOLU-MEDROL (34 patients)
ALPRAZOLAM (34 patients)
CO-TRIMOXAZOLE (34 patients)
AMITRIPTYLINE HCL (34 patients)
COREG (34 patients)
VITAMINS (UNSPECIFIED) (33 patients)
ACETYLSALICYLIC ACID (33 patients)
AZATHIOPRINE (33 patients)
ZOFRAN (33 patients)
CALTRATE +D (33 patients)
PROTEINASE INHIBITORS (33 patients)
CARTIA /USA/ (33 patients)
NIASPAN (33 patients)
PANTOPRAZOLE (33 patients)
MEGESTROL ACETATE (32 patients)
COMPAZINE (32 patients)
ADENOSINE (32 patients)
ALDACTONE (32 patients)
LANTUS (32 patients)
GASMOTIN (32 patients)
PROZAC (32 patients)
ARIMIDEX (31 patients)
AVELOX (31 patients)
FENTANYL (31 patients)
CALCIUM (UNSPECIFIED) (31 patients)
PAXIL (31 patients)
GLIPIZIDE (31 patients)
FLUCONAZOLE (31 patients)
ARANESP (31 patients)
CLARITIN (31 patients)
DILAUDID (31 patients)
NEUPOGEN (31 patients)
AVANDIA (31 patients)
B12 ^RECIP^ (30 patients)
K-DUR (30 patients)
CALCIUM CARBONATE (30 patients)
CELLCEPT (30 patients)
METFORMIN (30 patients)
CLOPIDOGREL (30 patients)
TRAMADOL HCL (30 patients)
REQUIP (29 patients)
CARVEDILOL (29 patients)
GLUCOPHAGE (29 patients)
FLOMAX (29 patients)
ZESTRIL (29 patients)
MIRTAZAPINE (29 patients)
TIAZAC (29 patients)
CAPECITABINE (29 patients)
KETEK (29 patients)
NICORANDIL (29 patients)
VERAPAMIL (29 patients)
CYMBALTA (28 patients)
RALTEGRAVIR (28 patients)
LOVASTATIN (28 patients)
CALCIUM (28 patients)
ACTOS (28 patients)
MICARDIS (28 patients)
DILTIAZEM HYDROCHLORIDE (28 patients)

Most common side effects for patients taking TOPROL-XL:

NAUSEA (3177 patients)
DYSPNOEA (3039 patients)
PAIN (2881 patients)
FATIGUE (2755 patients)
DIZZINESS (2659 patients)
MYOCARDIAL INFARCTION (2452 patients)
ANXIETY (2361 patients)
DIARRHOEA (2214 patients)
HYPERTENSION (2194 patients)
HEADACHE (2180 patients)
CHEST PAIN (2142 patients)
ASTHENIA (2126 patients)
DRUG INEFFECTIVE (1920 patients)
VOMITING (1669 patients)
CARDIAC FAILURE CONGESTIVE (1637 patients)
FALL (1619 patients)
OEDEMA PERIPHERAL (1601 patients)
BACK PAIN (1585 patients)
PAIN IN EXTREMITY (1571 patients)
DEPRESSION (1565 patients)
ANAEMIA (1481 patients)
CEREBROVASCULAR ACCIDENT (1459 patients)
WEIGHT DECREASED (1442 patients)
ATRIAL FIBRILLATION (1400 patients)
MALAISE (1368 patients)
INJURY (1354 patients)
ARTHRALGIA (1314 patients)
HYPOTENSION (1310 patients)
RENAL FAILURE (1309 patients)
BLOOD PRESSURE INCREASED (1280 patients)
PNEUMONIA (1268 patients)
INSOMNIA (1259 patients)
CORONARY ARTERY DISEASE (1251 patients)
COUGH (1138 patients)
ABDOMINAL PAIN (1101 patients)
BLOOD GLUCOSE INCREASED (1097 patients)
PYREXIA (1093 patients)
CONSTIPATION (1071 patients)
WEIGHT INCREASED (1069 patients)
PALPITATIONS (1027 patients)
DEHYDRATION (1000 patients)
CARDIAC DISORDER (953 patients)
HYPOAESTHESIA (951 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (929 patients)
URINARY TRACT INFECTION (895 patients)
PRURITUS (889 patients)
RASH (877 patients)
MYALGIA (873 patients)
ABDOMINAL PAIN UPPER (845 patients)
FEELING ABNORMAL (844 patients)
PARAESTHESIA (843 patients)
DIABETES MELLITUS (812 patients)
CONFUSIONAL STATE (803 patients)
EMOTIONAL DISTRESS (796 patients)
HEART RATE INCREASED (793 patients)
DEATH (787 patients)
MUSCLE SPASMS (780 patients)
VISION BLURRED (770 patients)
GAIT DISTURBANCE (755 patients)
SOMNOLENCE (748 patients)
RENAL FAILURE ACUTE (746 patients)
HYPERHIDROSIS (714 patients)
TREMOR (710 patients)
DRUG DOSE OMISSION (705 patients)
SYNCOPE (701 patients)
DECREASED APPETITE (687 patients)
BRONCHITIS (678 patients)
UNEVALUABLE EVENT (666 patients)
STRESS (662 patients)
OSTEOARTHRITIS (655 patients)
MEMORY IMPAIRMENT (646 patients)
PLEURAL EFFUSION (644 patients)
DYSPHAGIA (642 patients)
FLUSHING (626 patients)
DYSPEPSIA (622 patients)
ANHEDONIA (620 patients)
MUSCULAR WEAKNESS (608 patients)
LOSS OF CONSCIOUSNESS (600 patients)
TRANSIENT ISCHAEMIC ATTACK (597 patients)
CHEST DISCOMFORT (591 patients)
ARTHRITIS (585 patients)
CONVULSION (582 patients)
FEAR (572 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (567 patients)
AMNESIA (566 patients)
SINUSITIS (564 patients)
BLOOD CHOLESTEROL INCREASED (563 patients)
ALOPECIA (528 patients)
OSTEONECROSIS OF JAW (527 patients)
HAEMOGLOBIN DECREASED (522 patients)
ANGINA PECTORIS (516 patients)
MITRAL VALVE INCOMPETENCE (503 patients)
BONE DISORDER (501 patients)
ERYTHEMA (498 patients)
CONTUSION (491 patients)
RENAL IMPAIRMENT (491 patients)
CONDITION AGGRAVATED (487 patients)
NEUROPATHY PERIPHERAL (485 patients)
DEEP VEIN THROMBOSIS (470 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (468 patients)
ABDOMINAL DISCOMFORT (467 patients)
HYPERSENSITIVITY (466 patients)
ECONOMIC PROBLEM (466 patients)
NERVOUSNESS (464 patients)
SEPSIS (457 patients)
BLOOD CREATININE INCREASED (457 patients)
TACHYCARDIA (451 patients)
PULMONARY EMBOLISM (449 patients)
CATARACT (446 patients)
ACUTE MYOCARDIAL INFARCTION (440 patients)
GASTROINTESTINAL HAEMORRHAGE (438 patients)
THROMBOCYTOPENIA (431 patients)
ABDOMINAL DISTENSION (428 patients)
CHILLS (427 patients)
DRY MOUTH (427 patients)
SPINAL OSTEOARTHRITIS (426 patients)
ARTHROPATHY (423 patients)
INTERVERTEBRAL DISC PROTRUSION (422 patients)
BLOOD PRESSURE DECREASED (420 patients)
HYPERLIPIDAEMIA (417 patients)
ILL-DEFINED DISORDER (414 patients)
PAIN IN JAW (412 patients)
HEART RATE IRREGULAR (411 patients)
HYPOKALAEMIA (409 patients)
DYSGEUSIA (408 patients)
RESPIRATORY FAILURE (406 patients)
VISUAL IMPAIRMENT (406 patients)
THROMBOSIS (401 patients)
BRADYCARDIA (400 patients)
JOINT SWELLING (399 patients)
SWELLING (390 patients)
ARRHYTHMIA (389 patients)
CHOLELITHIASIS (388 patients)
MEDICATION ERROR (386 patients)
ASTHMA (384 patients)
CELLULITIS (382 patients)
NECK PAIN (379 patients)
MUSCULOSKELETAL PAIN (379 patients)
RENAL INJURY (377 patients)
ADVERSE EVENT (376 patients)
CORONARY ARTERY OCCLUSION (375 patients)
OSTEOPOROSIS (373 patients)
OSTEOMYELITIS (373 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (370 patients)
DRUG INTERACTION (367 patients)
CARDIOMEGALY (363 patients)
BLOOD GLUCOSE DECREASED (360 patients)
RECTAL HAEMORRHAGE (359 patients)
RENAL FAILURE CHRONIC (359 patients)
HALLUCINATION (352 patients)
SLEEP APNOEA SYNDROME (350 patients)
HEART RATE DECREASED (349 patients)
PHARMACEUTICAL PRODUCT COMPLAINT (345 patients)
CARDIAC ARREST (345 patients)
UPPER RESPIRATORY TRACT INFECTION (344 patients)
ATELECTASIS (343 patients)
BALANCE DISORDER (341 patients)
MYOCARDIAL ISCHAEMIA (338 patients)
TRICUSPID VALVE INCOMPETENCE (338 patients)
LETHARGY (336 patients)
MENTAL STATUS CHANGES (334 patients)
INFECTION (332 patients)
MULTI-ORGAN FAILURE (331 patients)
GASTRITIS (331 patients)
INFLUENZA LIKE ILLNESS (330 patients)
NASOPHARYNGITIS (330 patients)
OSTEONECROSIS (330 patients)
OEDEMA (326 patients)
INTERVERTEBRAL DISC DEGENERATION (325 patients)
VERTIGO (324 patients)
CARDIOMYOPATHY (323 patients)
DYSPNOEA EXERTIONAL (323 patients)
DRUG HYPERSENSITIVITY (322 patients)
URTICARIA (320 patients)
OFF LABEL USE (319 patients)
ABNORMAL DREAMS (318 patients)
BLOOD UREA INCREASED (314 patients)
MULTIPLE INJURIES (313 patients)
SLEEP DISORDER (312 patients)
ROAD TRAFFIC ACCIDENT (311 patients)
HAEMORRHAGE (311 patients)
ARTERIOSCLEROSIS (310 patients)
ABASIA (304 patients)
MUSCULOSKELETAL STIFFNESS (303 patients)
TINNITUS (303 patients)
VISUAL ACUITY REDUCED (300 patients)
PULMONARY HYPERTENSION (298 patients)
WHEEZING (297 patients)
OSTEOPENIA (295 patients)
TYPE 2 DIABETES MELLITUS (295 patients)
TOOTH EXTRACTION (294 patients)
IRRITABILITY (292 patients)
BURNING SENSATION (291 patients)
ACTIVITIES OF DAILY LIVING IMPAIRED (287 patients)
DYSURIA (286 patients)
EPISTAXIS (284 patients)
DYSPHONIA (284 patients)
BLOOD TRIGLYCERIDES INCREASED (283 patients)
HAEMORRHOIDS (282 patients)
POLLAKIURIA (278 patients)
PLATELET COUNT DECREASED (276 patients)
WRONG TECHNIQUE IN DRUG USAGE PROCESS (274 patients)
HYPERGLYCAEMIA (273 patients)
AGITATION (273 patients)
BONE PAIN (270 patients)
PULMONARY OEDEMA (270 patients)
PANIC ATTACK (270 patients)
NEOPLASM MALIGNANT (269 patients)
FLATULENCE (268 patients)
INCORRECT DOSE ADMINISTERED (265 patients)

In addition to reviewing our up-to-date FDA research, users may interact with the FactMed community - currently one million members and growing! FactMed online research and discussions are read by patients, scientists, physicians, and other interested health care parties. Post follow up Questions to learn from our diverse readership. Likewise, patients who have experienced unwanted effects are encouraged to share their Concerns to help educate and inform our members.

Recent FactMed Activity for TOPROL-XL

Issue	Description / Topic	Timestamp
QUESTION AORTIC ANEURYSM RUPTURE	I have been diagnosed with a 4.4 ascending aorta aneurysm and prescribed 25 mg of TOPROL-XL, how safe this drug and what is the pro's and con's?	2014-12-04 20:27:53
QUESTION T-CELL LYMPHOMA	Is ther a length of time associated with taking Toprol and the occurrence of T cell lymphoma?	2014-12-09 21:30:10
CONCERN T-CELL LYMPHOMA	I have been taking Toprol for years and just this year been diagnosed with Tcell lymphoma skin cancer.	2014-12-09 21:33:33
QUESTION TONGUE DRY	My tongue is real dry and white can topal xl cause this	2015-04-23 15:33:44
QUESTION GASTROOESOPHAGEAL REFLUX DISEASE	I think you will be fine. Things like ketchup, Tomatoes, hot sauce, cahtoloce, oranges, anything citrus, soda and anything with acid in it will trigger your acid reflux.	2015-07-13 07:33:15
QUESTION GOUT	i started methoprolol 2 year ago, in one month got the first gout episode.	2015-09-10 12:43:33
QUESTION ACUTE PROMYELOCYTIC LEUKAEMIA	I had acute promyelocytic leukemua in 2005 and and was put on the metoprolol succinate in 2015 at 50 mg a day. When standing for a time the toes on my left foot seem to turn purple. With my past history of APL should I be taking metoprolol succinate?	2015-10-27 06:20:04
QUESTION ACUTE PROMYELOCYTIC LEUKAEMIA	I had acute promyelocytic leukemua in 2005 and and was put on the metoprolol succinate in 2015 at 50 mg a day. When standing for a time the toes on my left foot seem to turn purple. With my past history of APL should I be taking metoprolol succinate?	2015-10-27 06:20:42
QUESTION DRUG INTERACTION	Is there an interaction with metoprolol ER succinate 200 and turmeric complex	2015-11-25 16:08:33
QUESTION RESTLESS LEGS SYNDROME	What helps restless leg syndrome the best?	2015-12-08 08:14:31
QUESTION GOUT	I have taken Toprol (Metoprol ol ER) for several years but have had much pain in my feet. Most recently in the last month I have had severe gout in my right arch. Could the Toprol be the cause of the gout and foot pain.?	2016-04-12 01:22:23
QUESTION CERVIX CANCER METASTATIC	Has toprol xl been linked to adenocarcinoma carcinoma of the cervix?	2016-08-05 11:27:35
QUESTION RENAL CYST	“U.S. intelligence bee#2ves&i8230;.”That&#8l17;s a really sweeping statement without any backup, wouldn’t you say?It’s almost like CNN has another agenda.But hey, that couldn’t be possible.Could it?	2017-03-20 11:19:13

My Patient Resources

Get your questions answered! Over one million patients, researchers, and health care providers have visited FactMed. If you have a question about myopathy and TOPROL-XL, post it here. You may receive a response from a fellow patient - or a leading expert in the field.

Your Question:

Share your experience: Over one million patients, researchers, and health care providers have visited FactMed. If you have a noteworthy experience as a patient taking TOPROL-XL, post it here. Your story could help a fellow patient - or provide insight to a leading expert in the field.

Your Experience or Concern:

Telemedicine Expert Consults FactMed newest feature allows patients to consult - via realtime videoconferencing - experts in TOPROL-XL. This premium feature connects patients to experts, regardless of geography. FactMed experts charge reasonable rates that may be reimbursable by your insurance as a second-opinion.

We are currently accepting registration for TOPROL-XL experts. If you are a healthcare provider experienced in prescribing TOPROL-XL, please register here.