About this FactMed analysis covering adverse side effect reports of TRICOR patients who developed myopathy.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 44 individuals taking TRICOR reported myopathy to the FDA. A total of 12749 TRICOR drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between TRICOR and myopathy. In doing so, we compare TRICOR with other drugs that cause myopathy, to help you evaluate whether or not TRICOR causes myopathy. Likewise, this page shows the most highly-reported side effects of TRICOR, so you can see if myopathy ranks among TRICOR's most well-known side effects.
Summary Statistics
Reports of TRICOR causing myopathy: 44
Reports of any side effect of TRICOR : 12749
Percentage of TRICOR patients where myopathy is a reported side effect: 0.3451%

FDA reports of any drug causing myopathy : 3605
Average percentage for all medicated patients where myopathy is reported as a complication: 0.0226%

Physician opinion on TRICOR as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing TRICOR:
BLOOD CHOLESTEROL INCREASED ( 1023 patients )
DRUG USE FOR UNKNOWN INDICATION ( 1010 patients )
BLOOD TRIGLYCERIDES INCREASED ( 803 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 714 patients )
HYPERLIPIDAEMIA ( 328 patients )
BLOOD CHOLESTEROL ( 282 patients )
HYPERCHOLESTEROLAEMIA ( 144 patients )
HYPERTRIGLYCERIDAEMIA ( 131 patients )
BLOOD TRIGLYCERIDES ( 104 patients )
DYSLIPIDAEMIA ( 83 patients )
BLOOD CHOLESTEROL ABNORMAL ( 63 patients )
BLOOD TRIGLYCERIDES ABNORMAL ( 46 patients )
HIGH DENSITY LIPOPROTEIN DECREASED ( 33 patients )
CARDIAC DISORDER ( 27 patients )
LOW DENSITY LIPOPROTEIN INCREASED ( 25 patients )
LIPIDS INCREASED ( 22 patients )
HYPERTENSION ( 12 patients )
FACTOR V LEIDEN MUTATION ( 8 patients )
BLOOD PRESSURE ( 7 patients )
LIPIDS ( 7 patients )
MIXED HYPERLIPIDAEMIA ( 7 patients )
ILL-DEFINED DISORDER ( 7 patients )
DIABETES MELLITUS ( 6 patients )
BLOOD CHOLESTEROL DECREASED ( 6 patients )
BLOOD VISCOSITY INCREASED ( 5 patients )
HIGH DENSITY LIPOPROTEIN INCREASED ( 5 patients )
CORONARY ARTERY DISEASE ( 5 patients )
TYPE IIA HYPERLIPIDAEMIA ( 4 patients )
FAMILIAL HYPERTRIGLYCERIDAEMIA ( 4 patients )
CARDIOVASCULAR EVENT PROPHYLAXIS ( 3 patients )
LIPIDS ABNORMAL ( 3 patients )
HYPERSENSITIVITY ( 3 patients )
CHEST PAIN ( 3 patients )
LIPIDOSIS ( 3 patients )
TYPE 2 DIABETES MELLITUS ( 2 patients )
TYPE IV HYPERLIPIDAEMIA ( 2 patients )
CHOLESTEROSIS ( 2 patients )
DIABETIC RETINOPATHY ( 2 patients )
LIPID METABOLISM DISORDER ( 2 patients )
VASCULAR GRAFT ( 2 patients )
LOW DENSITY LIPOPROTEIN ( 2 patients )
DIABETES MELLITUS NON-INSULIN-DEPENDENT ( 2 patients )
PROPHYLAXIS ( 2 patients )
GLIOBLASTOMA MULTIFORME ( 1 patients )
LIPIDS NORMAL ( 1 patients )
CONSTIPATION ( 1 patients )
MYOCARDIAL INFARCTION ( 1 patients )
OBESITY ( 1 patients )
INFECTION ( 1 patients )
LDL/HDL RATIO INCREASED ( 1 patients )
RHEUMATOID ARTHRITIS ( 1 patients )
GASTROINTESTINAL PAIN ( 1 patients )
THROMBOSIS ( 1 patients )
CARDIAC FAILURE ( 1 patients )
HEART RATE IRREGULAR ( 1 patients )
COELIAC DISEASE ( 1 patients )
NAUSEA ( 1 patients )
BLOOD GLUCOSE INCREASED ( 1 patients )
PRIMITIVE NEUROECTODERMAL TUMOUR ( 1 patients )
LABORATORY TEST ( 1 patients )
DYSTHYMIC DISORDER ( 1 patients )
LIP DISORDER ( 1 patients )
SYSTEMIC LUPUS ERYTHEMATOSUS ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with myopathy:

LIPITOR (517 patients)
ZOCOR (480 patients)
ASPIRIN (474 patients)
SIMVASTATIN (410 patients)
FOSAMAX (309 patients)
PREDNISONE (241 patients)
CRESTOR (239 patients)
ZOMETA (201 patients)
PREDNISOLONE (199 patients)
LASIX (177 patients)
FUROSEMIDE (162 patients)
ZETIA (153 patients)
HYDROCHLOROTHIAZIDE (144 patients)
PREDNISONE TAB (139 patients)
LEVOTHYROXINE SODIUM (138 patients)
VIOXX (130 patients)
ALLOPURINOL (125 patients)
DEXAMETHASONE (124 patients)
INSULIN (120 patients)
COUMADIN (118 patients)
CYCLOSPORINE (113 patients)
ATENOLOL (112 patients)
ATORVASTATIN CALCIUM (110 patients)
NORVASC (108 patients)
CLARITHROMYCIN (107 patients)
AMBIEN (104 patients)
MYCOPHENOLATE MOFETIL (103 patients)
LISINOPRIL (99 patients)
NOROXIN (98 patients)
DECADRON (97 patients)
OMEPRAZOLE (97 patients)
POTASSIUM CHLORIDE (96 patients)
SORAFENIB (RAF KINASE INHIBITOR) (95 patients)
GABAPENTIN (94 patients)
SYNTHROID (94 patients)
LAMIVUDINE (90 patients)
AMLODIPINE (90 patients)
RAMIPRIL (89 patients)
NEXIUM (88 patients)
PRILOSEC (87 patients)
METHYLPREDNISOLONE (85 patients)
WARFARIN SODIUM (83 patients)
ZIDOVUDINE (82 patients)
ALBUTEROL (82 patients)
LANSOPRAZOLE (80 patients)
MEK INHIBITOR (DIHYDROXYPROP-DIFLU-METHOXYPHEN-CYCLOPROPA-SULFAMI) (80 patients)
PROTONIX (79 patients)
ACETAMINOPHEN (77 patients)
FOLIC ACID (77 patients)
MULTI-VITAMINS (75 patients)
XANAX (75 patients)
COZAAR (73 patients)
NEURONTIN (73 patients)
REMICADE (71 patients)
REVLIMID (69 patients)
HUMIRA (68 patients)
AMIODARONE HCL (67 patients)
FLONASE (65 patients)
CELEXA (64 patients)
FERROUS SULFATE TAB (64 patients)
ATORVASTATIN (64 patients)
AMLODIPINE BESYLATE (64 patients)
SPIRONOLACTONE (63 patients)
MAGNEVIST (62 patients)
VYTORIN (62 patients)
ZOLOFT (61 patients)
PEPCID (60 patients)
PROGRAF (60 patients)
CITALOPRAM HYDROBROMIDE (59 patients)
VICODIN (59 patients)
ADVAIR DISKUS 100/50 (59 patients)
ULTRAVIST 150 (59 patients)
PLAVIX (59 patients)
METHOTREXATE (58 patients)
COLCHICINE (58 patients)
AREDIA (57 patients)
OXYCONTIN (57 patients)
LYRICA (57 patients)
DIDANOSINE (56 patients)
ENALAPRIL MALEATE (55 patients)
HEPARIN SODIUM INJECTION (55 patients)
TAMOXIFEN CITRATE (55 patients)
ACYCLOVIR (52 patients)
FENOFIBRATE (52 patients)
PRAVASTATIN (52 patients)
CLONAZEPAM (51 patients)
ITRACONAZOLE (51 patients)
CYCLOPHOSPHAMIDE (51 patients)
DIGOXIN (49 patients)
SEBIVO (49 patients)
TOPROL-XL (49 patients)
LORAZEPAM (48 patients)
DILTIAZEM (48 patients)
LORTAB (48 patients)
ELAVIL (47 patients)
DIFLUCAN (47 patients)
METOPROLOL TARTRATE (46 patients)
ATIVAN (46 patients)
VELCADE (45 patients)
ALENDRONATE SODIUM (45 patients)
VITAMIN D (45 patients)
KLOR-CON (45 patients)
PRAVACHOL (45 patients)
WELLBUTRIN (44 patients)
TRICOR (44 patients)
DARVOCET-N 100 (44 patients)
PERCOCET (44 patients)
RAPAMUNE (43 patients)
ASCORBIC ACID (43 patients)
LEVAQUIN (43 patients)
AROMASIN (43 patients)
DIAZEPAM (43 patients)
ZANTAC (43 patients)
GEMFIBROZIL (41 patients)
CELEBREX (41 patients)
OXYCODONE HCL (41 patients)
ABACAVIR (40 patients)
LEXAPRO (40 patients)
NIFEDIPINE (40 patients)
RADIATION THERAPY (39 patients)
ACETYLSALICYLIC ACID SRT (39 patients)
ACIPHEX (39 patients)
METFORMIN HCL (39 patients)
IRON (39 patients)
ALTACE (39 patients)
TACROLIMUS (38 patients)
EFAVIRENZ (38 patients)
ZYPREXA (38 patients)
ZYRTEC (38 patients)
LESCOL (37 patients)
[THERAPY UNSPECIFIED] (37 patients)
METOPROLOL (37 patients)
GLEEVEC (37 patients)
PANTOPRAZOLE SODIUM (36 patients)
FOSAMAX PLUS D (36 patients)
PROPRANOLOL HYDROCHLORIDE (36 patients)
EFFEXOR (36 patients)
AMIODARONE (36 patients)
CEFTRIAXONE (36 patients)
HERCEPTIN (35 patients)
THALIDOMIDE (35 patients)
FUSIDIC ACID (35 patients)
SINGULAIR (35 patients)
IBUPROFEN (35 patients)
SPIRIVA (35 patients)
LOSARTAN POTASSIUM (35 patients)
VANCOMYCIN (35 patients)
WARFARIN (34 patients)
PERIDEX (34 patients)
BISOPROLOL (34 patients)
HYZAAR (34 patients)
SIROLIMUS (34 patients)
SOLU-MEDROL (34 patients)
ALPRAZOLAM (34 patients)
CO-TRIMOXAZOLE (34 patients)
AMITRIPTYLINE HCL (34 patients)
COREG (34 patients)
VITAMINS (UNSPECIFIED) (33 patients)
ACETYLSALICYLIC ACID (33 patients)
AZATHIOPRINE (33 patients)
ZOFRAN (33 patients)
CALTRATE +D (33 patients)
PROTEINASE INHIBITORS (33 patients)
CARTIA /USA/ (33 patients)
NIASPAN (33 patients)
PANTOPRAZOLE (33 patients)
MEGESTROL ACETATE (32 patients)
COMPAZINE (32 patients)
ADENOSINE (32 patients)
ALDACTONE (32 patients)
LANTUS (32 patients)
GASMOTIN (32 patients)
PROZAC (32 patients)
ARIMIDEX (31 patients)
AVELOX (31 patients)
FENTANYL (31 patients)
CALCIUM (UNSPECIFIED) (31 patients)
PAXIL (31 patients)
GLIPIZIDE (31 patients)
FLUCONAZOLE (31 patients)
ARANESP (31 patients)
CLARITIN (31 patients)
DILAUDID (31 patients)
NEUPOGEN (31 patients)
AVANDIA (31 patients)
B12 ^RECIP^ (30 patients)
K-DUR (30 patients)
CALCIUM CARBONATE (30 patients)
CELLCEPT (30 patients)
METFORMIN (30 patients)
CLOPIDOGREL (30 patients)
TRAMADOL HCL (30 patients)
REQUIP (29 patients)
CARVEDILOL (29 patients)
GLUCOPHAGE (29 patients)
FLOMAX (29 patients)
ZESTRIL (29 patients)
MIRTAZAPINE (29 patients)
TIAZAC (29 patients)
CAPECITABINE (29 patients)
KETEK (29 patients)
NICORANDIL (29 patients)
VERAPAMIL (29 patients)
CYMBALTA (28 patients)
RALTEGRAVIR (28 patients)
LOVASTATIN (28 patients)
CALCIUM (28 patients)
ACTOS (28 patients)
MICARDIS (28 patients)
DILTIAZEM HYDROCHLORIDE (28 patients)
Most common side effects for patients taking TRICOR:
NAUSEA (1046 patients)
FATIGUE (834 patients)
PAIN (797 patients)
DYSPNOEA (788 patients)
DIZZINESS (761 patients)
ASTHENIA (689 patients)
MYOCARDIAL INFARCTION (672 patients)
DIARRHOEA (624 patients)
CHEST PAIN (624 patients)
DRUG INEFFECTIVE (615 patients)
BLOOD GLUCOSE INCREASED (615 patients)
WEIGHT DECREASED (608 patients)
ANXIETY (604 patients)
HEADACHE (579 patients)
VOMITING (549 patients)
ARTHRALGIA (548 patients)
DEPRESSION (536 patients)
FLUSHING (525 patients)
MYALGIA (523 patients)
PAIN IN EXTREMITY (510 patients)
OEDEMA PERIPHERAL (487 patients)
BACK PAIN (455 patients)
PANCREATITIS (451 patients)
INSOMNIA (450 patients)
ABDOMINAL PAIN (416 patients)
WEIGHT INCREASED (413 patients)
DIABETES MELLITUS (412 patients)
MUSCLE SPASMS (409 patients)
FALL (405 patients)
HYPERTENSION (400 patients)
CORONARY ARTERY DISEASE (396 patients)
CARDIAC FAILURE CONGESTIVE (395 patients)
ANAEMIA (393 patients)
BLOOD TRIGLYCERIDES INCREASED (389 patients)
RENAL FAILURE (383 patients)
PRURITUS (378 patients)
ABDOMINAL PAIN UPPER (348 patients)
PNEUMONIA (326 patients)
DEHYDRATION (313 patients)
RASH (311 patients)
MALAISE (295 patients)
BLOOD CHOLESTEROL INCREASED (294 patients)
RENAL FAILURE ACUTE (291 patients)
FEELING ABNORMAL (288 patients)
CONSTIPATION (284 patients)
ATRIAL FIBRILLATION (283 patients)
PARAESTHESIA (282 patients)
HYPOTENSION (282 patients)
CEREBROVASCULAR ACCIDENT (277 patients)
PYREXIA (274 patients)
INJURY (270 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (261 patients)
COUGH (261 patients)
TYPE 2 DIABETES MELLITUS (260 patients)
PALPITATIONS (250 patients)
URINARY TRACT INFECTION (250 patients)
HYPOAESTHESIA (246 patients)
MUSCULAR WEAKNESS (242 patients)
DECREASED APPETITE (242 patients)
SOMNOLENCE (240 patients)
HYPERHIDROSIS (232 patients)
CARDIAC DISORDER (231 patients)
GAIT DISTURBANCE (223 patients)
ERYTHEMA (221 patients)
EMOTIONAL DISTRESS (217 patients)
BLOOD CREATININE INCREASED (216 patients)
HYPERLIPIDAEMIA (215 patients)
CONFUSIONAL STATE (214 patients)
CHOLELITHIASIS (209 patients)
LOSS OF CONSCIOUSNESS (202 patients)
BLOOD GLUCOSE DECREASED (201 patients)
VISION BLURRED (201 patients)
DYSPEPSIA (192 patients)
PANCREATITIS ACUTE (191 patients)
TREMOR (189 patients)
DRUG INTERACTION (185 patients)
DEATH (181 patients)
NEUROPATHY PERIPHERAL (178 patients)
RHABDOMYOLYSIS (175 patients)
OSTEOARTHRITIS (174 patients)
CHEST DISCOMFORT (171 patients)
AMNESIA (169 patients)
DEEP VEIN THROMBOSIS (164 patients)
CONDITION AGGRAVATED (162 patients)
BLOOD PRESSURE INCREASED (160 patients)
ABDOMINAL DISTENSION (159 patients)
SUICIDAL IDEATION (158 patients)
DRY MOUTH (155 patients)
HEPATIC ENZYME INCREASED (149 patients)
DYSPHAGIA (148 patients)
ABDOMINAL DISCOMFORT (146 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (146 patients)
ACUTE MYOCARDIAL INFARCTION (146 patients)
PULMONARY EMBOLISM (146 patients)
FEELING HOT (144 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (144 patients)
URTICARIA (142 patients)
LIVER FUNCTION TEST ABNORMAL (142 patients)
HYPERGLYCAEMIA (142 patients)
CELLULITIS (140 patients)
ANHEDONIA (139 patients)
UNEVALUABLE EVENT (138 patients)
RENAL IMPAIRMENT (138 patients)
HEPATIC STEATOSIS (137 patients)
NERVOUSNESS (137 patients)
CONVULSION (137 patients)
ECONOMIC PROBLEM (136 patients)
DIABETES MELLITUS INADEQUATE CONTROL (136 patients)
OFF LABEL USE (136 patients)
STRESS (134 patients)
BALANCE DISORDER (134 patients)
ANGINA PECTORIS (133 patients)
PLEURAL EFFUSION (131 patients)
ARTHRITIS (131 patients)
ALOPECIA (127 patients)
NECK PAIN (127 patients)
JOINT SWELLING (127 patients)
TRANSIENT ISCHAEMIC ATTACK (126 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (126 patients)
HYPOGLYCAEMIA (126 patients)
BURNING SENSATION (122 patients)
CORONARY ARTERY OCCLUSION (120 patients)
SLEEP APNOEA SYNDROME (120 patients)
CHILLS (119 patients)
MUSCULOSKELETAL PAIN (119 patients)
SYNCOPE (118 patients)
SINUSITIS (118 patients)
BRONCHITIS (118 patients)
HYPERSENSITIVITY (117 patients)
HAEMOGLOBIN DECREASED (116 patients)
INTERVERTEBRAL DISC PROTRUSION (116 patients)
VERTIGO (115 patients)
RENAL FAILURE CHRONIC (114 patients)
MEMORY IMPAIRMENT (113 patients)
DYSGEUSIA (113 patients)
ALANINE AMINOTRANSFERASE INCREASED (111 patients)
FEAR (111 patients)
OBESITY (110 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (109 patients)
HALLUCINATION (107 patients)
THROMBOSIS (106 patients)
CONTUSION (105 patients)
OSTEONECROSIS OF JAW (105 patients)
CARDIOMEGALY (104 patients)
MULTIPLE INJURIES (104 patients)
LETHARGY (103 patients)
ARTERIOSCLEROSIS (103 patients)
PHARMACEUTICAL PRODUCT COMPLAINT (102 patients)
HEART RATE INCREASED (102 patients)
CATARACT (102 patients)
INJECTION SITE PAIN (102 patients)
FLATULENCE (101 patients)
RESPIRATORY FAILURE (100 patients)
HIGH DENSITY LIPOPROTEIN DECREASED (99 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (96 patients)
STAPHYLOCOCCAL INFECTION (95 patients)
ABASIA (94 patients)
OVERDOSE (94 patients)
ASTHMA (92 patients)
MITRAL VALVE INCOMPETENCE (92 patients)
HYPOTHYROIDISM (92 patients)
INFLUENZA LIKE ILLNESS (92 patients)
MULTI-ORGAN FAILURE (91 patients)
DYSURIA (91 patients)
OSTEOMYELITIS (90 patients)
AGITATION (89 patients)
MOBILITY DECREASED (89 patients)
CARDIO-RESPIRATORY ARREST (88 patients)
NASOPHARYNGITIS (88 patients)
BLOOD UREA INCREASED (88 patients)
CARDIAC ARREST (88 patients)
OEDEMA (87 patients)
ABNORMAL DREAMS (86 patients)
HYPERTRIGLYCERIDAEMIA (86 patients)
SLEEP DISORDER (86 patients)
RENAL DISORDER (86 patients)
MYOCARDIAL ISCHAEMIA (85 patients)
SEPSIS (85 patients)
RECTAL HAEMORRHAGE (84 patients)
NEPHROLITHIASIS (84 patients)
SKIN BURNING SENSATION (84 patients)
DRY SKIN (82 patients)
MUSCULOSKELETAL STIFFNESS (82 patients)
DRUG DOSE OMISSION (82 patients)
BLOOD PRESSURE DECREASED (82 patients)
TRICUSPID VALVE INCOMPETENCE (81 patients)
SWELLING (81 patients)
INTERVERTEBRAL DISC DEGENERATION (81 patients)
ERECTILE DYSFUNCTION (81 patients)
OSTEONECROSIS (80 patients)
DIABETIC NEUROPATHY (80 patients)
EPISTAXIS (80 patients)
HYPOKALAEMIA (80 patients)
INCORRECT DOSE ADMINISTERED (79 patients)
BONE DISORDER (79 patients)
DIABETIC KETOACIDOSIS (78 patients)
SKIN ULCER (78 patients)
PULMONARY OEDEMA (78 patients)
PRODUCT QUALITY ISSUE (77 patients)
WRONG TECHNIQUE IN DRUG USAGE PROCESS (77 patients)
DRUG HYPERSENSITIVITY (77 patients)
HEART RATE IRREGULAR (77 patients)
ANOREXIA (77 patients)
UPPER RESPIRATORY TRACT INFECTION (76 patients)
ANGER (76 patients)
POLLAKIURIA (76 patients)
INFECTION (75 patients)
GASTROINTESTINAL HAEMORRHAGE (74 patients)
HEPATITIS (73 patients)
SCAR (73 patients)

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Recent FactMed Activity for TRICOR


Issue Description / Topic Timestamp
QUESTION
PROSTATE CANCER STAGE II
What are the chances that, as a result of taking Tricor beginning in 1996, a man could causatively develop Prostate Cancer in 2000? And then, as a result of taking Gemfibrozil beginning in approx. 2008 (after being taken off Tricor), the patient could have developed Thyroid Cancer in Spring of 2013, and finally been diagnosed with Pancreatic Cancer in May of 2013? 2015-01-03 19:23:52
QUESTION
LUPUS-LIKE SYNDROME
I have taken tricor. Developed what was called, drug induced lupus. Was taken off the drug and told it would resolve itself. That was thirty years ago. I still have it. Any suggestions? 2015-04-18 00:18:22
QUESTION
PANCREATIC CYST
I was diagnosed with a serous cystadenoma in the head of my pancreas after taking Tricor at the age of 48. I would like to hear others stories if you have one. Thank you 2015-05-14 09:27:27
QUESTION
BILE DUCT STONE
I have been taking tricor and developed a bile duct stone . Do you think it is caused from taking the Tricor medication? 2015-07-11 10:53:36
QUESTION
BILE DUCT STONE
I have been taking tricor and developed a bile duct stone . Do you think it is caused from taking the Tricor medication? 2015-07-11 11:06:12
QUESTION
NEUROPATHY PERIPHERAL
Can tricor cause peripheral neuropathy 2015-10-29 01:43:33
QUESTION
MANIA
Can Tricor in elderly cause mania 2016-03-28 20:58:49
QUESTION
DEHYDRATION
Can tricor dehydrate your muscles to the point of pain? 2016-10-02 17:59:21
QUESTION
INTERCOSTAL NEURALGIA
I stopped taking tricor,and lipitor on 8/1/2016 because of muscle spasms in my rib cage and my ribs felt like razor digging into my spine, also spasm in right hip. I don't know that tricor was the cause but I'm feeling better now but still have nausea. How long does it take to leave your system? 2016-10-08 13:54:21

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