Is myopathy a side effect of VELCADE ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of VELCADE patients who developed myopathy.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 45 individuals taking VELCADE reported myopathy to the FDA. A total of 19701 VELCADE drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between VELCADE and myopathy. In doing so, we compare VELCADE with other drugs that cause myopathy, to help you evaluate whether or not VELCADE causes myopathy. Likewise, this page shows the most highly-reported side effects of VELCADE, so you can see if myopathy ranks among VELCADE's most well-known side effects.

Summary Statistics
Reports of VELCADE causing myopathy: 45
Reports of any side effect of VELCADE : 19701
Percentage of VELCADE patients where myopathy is a reported side effect: 0.2284%

FDA reports of any drug causing myopathy : 3605
Average percentage for all medicated patients where myopathy is reported as a complication: 0.0226%

Physician opinion on VELCADE as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing VELCADE:

MULTIPLE MYELOMA ( 12053 patients )
DRUG USE FOR UNKNOWN INDICATION ( 609 patients )
MANTLE CELL LYMPHOMA ( 480 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 345 patients )
ACUTE MYELOID LEUKAEMIA ( 225 patients )
AMYLOIDOSIS ( 162 patients )
LEUKAEMIA PLASMACYTIC ( 140 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 136 patients )
NON-SMALL CELL LUNG CANCER ( 117 patients )
NON-HODGKIN'S LYMPHOMA ( 116 patients )
T-CELL LYMPHOMA ( 108 patients )
PLASMACYTOMA ( 96 patients )
LYMPHOMA ( 95 patients )
B-CELL LYMPHOMA ( 84 patients )
WALDENSTROM'S MACROGLOBULINAEMIA ( 68 patients )
MYELODYSPLASTIC SYNDROME ( 58 patients )
ACUTE LYMPHOCYTIC LEUKAEMIA ( 49 patients )
HEAD AND NECK CANCER ( 34 patients )
CHEMOTHERAPY ( 33 patients )
B PRECURSOR TYPE ACUTE LEUKAEMIA ( 33 patients )
NEUROBLASTOMA ( 32 patients )
TRANSPLANT REJECTION ( 31 patients )
PRIMARY AMYLOIDOSIS ( 29 patients )
TRANSITIONAL CELL CARCINOMA ( 28 patients )
SQUAMOUS CELL CARCINOMA ( 24 patients )
GLIOBLASTOMA MULTIFORME ( 23 patients )
NEOPLASM MALIGNANT ( 21 patients )
PERIPHERAL T-CELL LYMPHOMA UNSPECIFIED ( 21 patients )
RENAL TRANSPLANT ( 20 patients )
CHRONIC LYMPHOCYTIC LEUKAEMIA ( 19 patients )
COLORECTAL CANCER ( 19 patients )
HODGKIN'S DISEASE ( 17 patients )
LUNG NEOPLASM MALIGNANT ( 17 patients )
MYELOMA RECURRENCE ( 17 patients )
MALIGNANT MELANOMA ( 17 patients )
PROSTATE CANCER ( 15 patients )
MEDICATION ERROR ( 15 patients )
CARDIAC AMYLOIDOSIS ( 14 patients )
BREAST CANCER ( 14 patients )
OVARIAN CANCER ( 13 patients )
NEOPLASM ( 13 patients )
KIDNEY TRANSPLANT REJECTION ( 12 patients )
RENAL AMYLOIDOSIS ( 12 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 11 patients )
PROPHYLAXIS AGAINST TRANSPLANT REJECTION ( 10 patients )
MYELOFIBROSIS ( 10 patients )
LEUKAEMIA ( 9 patients )
REFRACTORY CANCER ( 9 patients )
ADENOCARCINOMA ( 9 patients )
MESOTHELIOMA MALIGNANT ( 9 patients )
ADENOID CYSTIC CARCINOMA ( 8 patients )
PRECURSOR T-LYMPHOBLASTIC LYMPHOMA/LEUKAEMIA ( 8 patients )
RENAL CELL CARCINOMA STAGE UNSPECIFIED ( 8 patients )
EXTRANODAL MARGINAL ZONE B-CELL LYMPHOMA (MALT TYPE) ( 8 patients )
MALIGNANT GLIOMA ( 7 patients )
ACCIDENTAL EXPOSURE ( 7 patients )
SALIVARY GLAND CANCER ( 7 patients )
METASTATIC MALIGNANT MELANOMA ( 7 patients )
PANCREATIC CARCINOMA ( 7 patients )
CHRONIC MYELOID LEUKAEMIA ( 6 patients )
LIP AND/OR ORAL CAVITY CANCER ( 6 patients )
MULTIPLE SCLEROSIS ( 6 patients )
BRAIN NEOPLASM ( 6 patients )
ANAPLASTIC LARGE CELL LYMPHOMA T- AND NULL-CELL TYPES ( 6 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 6 patients )
GLIOBLASTOMA ( 5 patients )
COLON CANCER ( 5 patients )
ACUTE LEUKAEMIA ( 5 patients )
RENAL CELL CARCINOMA ( 5 patients )
IMMUNOSUPPRESSION ( 5 patients )
MESOTHELIOMA ( 5 patients )
GASTRIC CANCER ( 5 patients )
BRONCHIOLOALVEOLAR CARCINOMA ( 5 patients )
HEPATIC NEOPLASM MALIGNANT ( 4 patients )
THYROID CANCER ( 4 patients )
IMMUNE TOLERANCE INDUCTION ( 4 patients )
OVARIAN EPITHELIAL CANCER ( 4 patients )
LYMPHOMA AIDS RELATED ( 4 patients )
LARYNGEAL CANCER ( 4 patients )
PLASMABLASTIC LYMPHOMA ( 4 patients )
HEART TRANSPLANT ( 4 patients )
LUNG SQUAMOUS CELL CARCINOMA STAGE UNSPECIFIED ( 4 patients )
OVARIAN CANCER RECURRENT ( 4 patients )
PROPHYLAXIS ( 4 patients )
NEOPLASM RECURRENCE ( 3 patients )
RECTAL CANCER ( 3 patients )
MALIGNANT PERITONEAL NEOPLASM ( 3 patients )
EPSTEIN-BARR VIRAEMIA ( 3 patients )
OVARIAN CANCER METASTATIC ( 3 patients )
FOLLICLE CENTRE LYMPHOMA, FOLLICULAR GRADE I, II, III ( 3 patients )
LYMPHOCYTIC LYMPHOMA ( 3 patients )
NATURAL KILLER-CELL LYMPHOBLASTIC LYMPHOMA ( 3 patients )
LUNG ADENOCARCINOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IIIA ( 3 patients )
LUNG CARCINOMA CELL TYPE UNSPECIFIED RECURRENT ( 3 patients )
MASS ( 3 patients )
IMMUNOMODULATORY THERAPY ( 3 patients )
SALVAGE THERAPY ( 3 patients )
PANCREATIC CARCINOMA METASTATIC ( 2 patients )
COLORECTAL CANCER METASTATIC ( 2 patients )
BONE MARROW CONDITIONING REGIMEN ( 2 patients )
MANTLE CELL LYMPHOMA RECURRENT ( 2 patients )
NON-SMALL CELL LUNG CANCER STAGE III ( 2 patients )
PLEURAL MESOTHELIOMA ( 2 patients )
MANTLE CELL LYMPHOMA STAGE IV ( 2 patients )
MYELOID LEUKAEMIA ( 2 patients )
TONGUE CANCER METASTATIC ( 2 patients )
LUNG TRANSPLANT REJECTION ( 2 patients )
MACULAR OEDEMA ( 2 patients )
PROSTATE CANCER METASTATIC ( 2 patients )
CHRONIC MYELOMONOCYTIC LEUKAEMIA ( 2 patients )
NON-HODGKIN'S LYMPHOMA STAGE IV ( 2 patients )
LIVER DISORDER ( 2 patients )
ACUTE GRAFT VERSUS HOST DISEASE ( 2 patients )
HEPATOSPLENIC T-CELL LYMPHOMA ( 2 patients )
RENAL CANCER METASTATIC ( 2 patients )
DISEASE PROGRESSION ( 2 patients )
EPITHELIOID SARCOMA ( 2 patients )
MYELOID METAPLASIA ( 2 patients )
TONSIL CANCER ( 2 patients )
GASTRIC ADENOMA ( 2 patients )
LARGE GRANULAR LYMPHOCYTOSIS ( 1 patients )
METASTASIS ( 1 patients )
PANCREAS TRANSPLANT REJECTION ( 1 patients )
ANTI-INFECTIVE THERAPY ( 1 patients )
LYMPHOPLASMACYTOID LYMPHOMA/IMMUNOCYTOMA ( 1 patients )
METASTATIC NEOPLASM ( 1 patients )
SOFT TISSUE NEOPLASM ( 1 patients )
GRANULOMA ( 1 patients )
MONOCLONAL GAMMOPATHY ( 1 patients )
PHARYNGEAL CANCER METASTATIC ( 1 patients )
SYSTEMIC SCLEROSIS ( 1 patients )
B-CELL LYMPHOMA RECURRENT ( 1 patients )
NON-RENAL CELL CARCINOMA OF KIDNEY ( 1 patients )
LIVER TRANSPLANT REJECTION ( 1 patients )
RENAL CANCER ( 1 patients )
LUNG ADENOCARCINOMA STAGE IV ( 1 patients )
OESOPHAGEAL CARCINOMA RECURRENT ( 1 patients )
POST TRANSPLANT LYMPHOPROLIFERATIVE DISORDER ( 1 patients )
BREAST CANCER METASTATIC ( 1 patients )
ORAL CAVITY CANCER METASTATIC ( 1 patients )
RENAL DISORDER ( 1 patients )
TRACHEAL CANCER ( 1 patients )
ADRENOCORTICAL CARCINOMA ( 1 patients )
CERVIX CARCINOMA ( 1 patients )
METASTASES TO LARYNX ( 1 patients )
SMALL CELL LUNG CANCER METASTATIC ( 1 patients )
SMALL INTESTINE CARCINOMA METASTATIC ( 1 patients )
ANTIBODY TEST ABNORMAL ( 1 patients )
HAIRY CELL LEUKAEMIA ( 1 patients )
RECURRENT CANCER ( 1 patients )
ACCIDENT ( 1 patients )
T-CELL CHRONIC LYMPHOCYTIC LEUKAEMIA ( 1 patients )
B-CELL LYMPHOMA REFRACTORY ( 1 patients )
CRYOGLOBULINAEMIA ( 1 patients )
MYCOSIS FUNGOIDES ( 1 patients )
PLASMACYTOSIS ( 1 patients )
T-CELL TYPE ACUTE LEUKAEMIA ( 1 patients )
BONE NEOPLASM MALIGNANT ( 1 patients )
MANTLE CELL LYMPHOMA STAGE III ( 1 patients )
PLEURAL MESOTHELIOMA MALIGNANT ( 1 patients )
THYROID CANCER METASTATIC ( 1 patients )
HYPERGAMMAGLOBULINAEMIA BENIGN MONOCLONAL ( 1 patients )
OFF LABEL USE ( 1 patients )
PRECURSOR B-LYMPHOBLASTIC LYMPHOMA ( 1 patients )
MENINGIOMA ( 1 patients )
ADENOIDAL DISORDER ( 1 patients )
LYMPHOCYTIC LEUKAEMIA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
TRACHEAL DISORDER ( 1 patients )
CENTRAL NERVOUS SYSTEM NEOPLASM ( 1 patients )
KAPOSI'S SARCOMA AIDS RELATED ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with myopathy:

LIPITOR (517 patients)
ZOCOR (480 patients)
ASPIRIN (474 patients)
SIMVASTATIN (410 patients)
FOSAMAX (309 patients)
PREDNISONE (241 patients)
CRESTOR (239 patients)
ZOMETA (201 patients)
PREDNISOLONE (199 patients)
LASIX (177 patients)
FUROSEMIDE (162 patients)
ZETIA (153 patients)
HYDROCHLOROTHIAZIDE (144 patients)
PREDNISONE TAB (139 patients)
LEVOTHYROXINE SODIUM (138 patients)
VIOXX (130 patients)
ALLOPURINOL (125 patients)
DEXAMETHASONE (124 patients)
INSULIN (120 patients)
COUMADIN (118 patients)
CYCLOSPORINE (113 patients)
ATENOLOL (112 patients)
ATORVASTATIN CALCIUM (110 patients)
NORVASC (108 patients)
CLARITHROMYCIN (107 patients)
AMBIEN (104 patients)
MYCOPHENOLATE MOFETIL (103 patients)
LISINOPRIL (99 patients)
NOROXIN (98 patients)
DECADRON (97 patients)
OMEPRAZOLE (97 patients)
POTASSIUM CHLORIDE (96 patients)
SORAFENIB (RAF KINASE INHIBITOR) (95 patients)
GABAPENTIN (94 patients)
SYNTHROID (94 patients)
LAMIVUDINE (90 patients)
AMLODIPINE (90 patients)
RAMIPRIL (89 patients)
NEXIUM (88 patients)
PRILOSEC (87 patients)
METHYLPREDNISOLONE (85 patients)
WARFARIN SODIUM (83 patients)
ZIDOVUDINE (82 patients)
ALBUTEROL (82 patients)
LANSOPRAZOLE (80 patients)
MEK INHIBITOR (DIHYDROXYPROP-DIFLU-METHOXYPHEN-CYCLOPROPA-SULFAMI) (80 patients)
PROTONIX (79 patients)
ACETAMINOPHEN (77 patients)
FOLIC ACID (77 patients)
MULTI-VITAMINS (75 patients)
XANAX (75 patients)
COZAAR (73 patients)
NEURONTIN (73 patients)
REMICADE (71 patients)
REVLIMID (69 patients)
HUMIRA (68 patients)
AMIODARONE HCL (67 patients)
FLONASE (65 patients)
CELEXA (64 patients)
FERROUS SULFATE TAB (64 patients)
ATORVASTATIN (64 patients)
AMLODIPINE BESYLATE (64 patients)
SPIRONOLACTONE (63 patients)
MAGNEVIST (62 patients)
VYTORIN (62 patients)
ZOLOFT (61 patients)
PEPCID (60 patients)
PROGRAF (60 patients)
CITALOPRAM HYDROBROMIDE (59 patients)
VICODIN (59 patients)
ADVAIR DISKUS 100/50 (59 patients)
ULTRAVIST 150 (59 patients)
PLAVIX (59 patients)
METHOTREXATE (58 patients)
COLCHICINE (58 patients)
AREDIA (57 patients)
OXYCONTIN (57 patients)
LYRICA (57 patients)
DIDANOSINE (56 patients)
ENALAPRIL MALEATE (55 patients)
HEPARIN SODIUM INJECTION (55 patients)
TAMOXIFEN CITRATE (55 patients)
ACYCLOVIR (52 patients)
FENOFIBRATE (52 patients)
PRAVASTATIN (52 patients)
CLONAZEPAM (51 patients)
ITRACONAZOLE (51 patients)
CYCLOPHOSPHAMIDE (51 patients)
DIGOXIN (49 patients)
SEBIVO (49 patients)
TOPROL-XL (49 patients)
LORAZEPAM (48 patients)
DILTIAZEM (48 patients)
LORTAB (48 patients)
ELAVIL (47 patients)
DIFLUCAN (47 patients)
METOPROLOL TARTRATE (46 patients)
ATIVAN (46 patients)
VELCADE (45 patients)
ALENDRONATE SODIUM (45 patients)
VITAMIN D (45 patients)
KLOR-CON (45 patients)
PRAVACHOL (45 patients)
WELLBUTRIN (44 patients)
TRICOR (44 patients)
DARVOCET-N 100 (44 patients)
PERCOCET (44 patients)
RAPAMUNE (43 patients)
ASCORBIC ACID (43 patients)
LEVAQUIN (43 patients)
AROMASIN (43 patients)
DIAZEPAM (43 patients)
ZANTAC (43 patients)
GEMFIBROZIL (41 patients)
CELEBREX (41 patients)
OXYCODONE HCL (41 patients)
ABACAVIR (40 patients)
LEXAPRO (40 patients)
NIFEDIPINE (40 patients)
RADIATION THERAPY (39 patients)
ACETYLSALICYLIC ACID SRT (39 patients)
ACIPHEX (39 patients)
METFORMIN HCL (39 patients)
IRON (39 patients)
ALTACE (39 patients)
TACROLIMUS (38 patients)
EFAVIRENZ (38 patients)
ZYPREXA (38 patients)
ZYRTEC (38 patients)
LESCOL (37 patients)
[THERAPY UNSPECIFIED] (37 patients)
METOPROLOL (37 patients)
GLEEVEC (37 patients)
PANTOPRAZOLE SODIUM (36 patients)
FOSAMAX PLUS D (36 patients)
PROPRANOLOL HYDROCHLORIDE (36 patients)
EFFEXOR (36 patients)
AMIODARONE (36 patients)
CEFTRIAXONE (36 patients)
HERCEPTIN (35 patients)
THALIDOMIDE (35 patients)
FUSIDIC ACID (35 patients)
SINGULAIR (35 patients)
IBUPROFEN (35 patients)
SPIRIVA (35 patients)
LOSARTAN POTASSIUM (35 patients)
VANCOMYCIN (35 patients)
WARFARIN (34 patients)
PERIDEX (34 patients)
BISOPROLOL (34 patients)
HYZAAR (34 patients)
SIROLIMUS (34 patients)
SOLU-MEDROL (34 patients)
ALPRAZOLAM (34 patients)
CO-TRIMOXAZOLE (34 patients)
AMITRIPTYLINE HCL (34 patients)
COREG (34 patients)
VITAMINS (UNSPECIFIED) (33 patients)
ACETYLSALICYLIC ACID (33 patients)
AZATHIOPRINE (33 patients)
ZOFRAN (33 patients)
CALTRATE +D (33 patients)
PROTEINASE INHIBITORS (33 patients)
CARTIA /USA/ (33 patients)
NIASPAN (33 patients)
PANTOPRAZOLE (33 patients)
MEGESTROL ACETATE (32 patients)
COMPAZINE (32 patients)
ADENOSINE (32 patients)
ALDACTONE (32 patients)
LANTUS (32 patients)
GASMOTIN (32 patients)
PROZAC (32 patients)
ARIMIDEX (31 patients)
AVELOX (31 patients)
FENTANYL (31 patients)
CALCIUM (UNSPECIFIED) (31 patients)
PAXIL (31 patients)
GLIPIZIDE (31 patients)
FLUCONAZOLE (31 patients)
ARANESP (31 patients)
CLARITIN (31 patients)
DILAUDID (31 patients)
NEUPOGEN (31 patients)
AVANDIA (31 patients)
B12 ^RECIP^ (30 patients)
K-DUR (30 patients)
CALCIUM CARBONATE (30 patients)
CELLCEPT (30 patients)
METFORMIN (30 patients)
CLOPIDOGREL (30 patients)
TRAMADOL HCL (30 patients)
REQUIP (29 patients)
CARVEDILOL (29 patients)
GLUCOPHAGE (29 patients)
FLOMAX (29 patients)
ZESTRIL (29 patients)
MIRTAZAPINE (29 patients)
TIAZAC (29 patients)
CAPECITABINE (29 patients)
KETEK (29 patients)
NICORANDIL (29 patients)
VERAPAMIL (29 patients)
CYMBALTA (28 patients)
RALTEGRAVIR (28 patients)
LOVASTATIN (28 patients)
CALCIUM (28 patients)
ACTOS (28 patients)
MICARDIS (28 patients)
DILTIAZEM HYDROCHLORIDE (28 patients)

Most common side effects for patients taking VELCADE:

DIARRHOEA (1758 patients)
NEUROPATHY PERIPHERAL (1641 patients)
PNEUMONIA (1572 patients)
THROMBOCYTOPENIA (1495 patients)
MULTIPLE MYELOMA (1480 patients)
PYREXIA (1406 patients)
DEATH (1360 patients)
DISEASE PROGRESSION (1314 patients)
PLATELET COUNT DECREASED (1205 patients)
ANAEMIA (1192 patients)
PAIN (1123 patients)
DYSPNOEA (1120 patients)
NAUSEA (1105 patients)
ASTHENIA (1063 patients)
FATIGUE (1054 patients)
HYPOTENSION (950 patients)
CONSTIPATION (848 patients)
VOMITING (830 patients)
RENAL FAILURE ACUTE (764 patients)
PANCYTOPENIA (754 patients)
DEHYDRATION (749 patients)
HAEMOGLOBIN DECREASED (734 patients)
PLEURAL EFFUSION (729 patients)
SEPSIS (704 patients)
INFECTION (670 patients)
ANXIETY (657 patients)
RENAL FAILURE (641 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (620 patients)
BACK PAIN (607 patients)
FALL (599 patients)
HYPOAESTHESIA (590 patients)
OEDEMA PERIPHERAL (581 patients)
OSTEONECROSIS OF JAW (578 patients)
WHITE BLOOD CELL COUNT DECREASED (567 patients)
NEUTROPENIA (566 patients)
BONE DISORDER (549 patients)
ABDOMINAL PAIN (528 patients)
HERPES ZOSTER (525 patients)
ATRIAL FIBRILLATION (525 patients)
DIZZINESS (519 patients)
CHEST PAIN (504 patients)
DECREASED APPETITE (501 patients)
PAIN IN EXTREMITY (497 patients)
RESPIRATORY FAILURE (489 patients)
OSTEONECROSIS (457 patients)
RASH (449 patients)
MALIGNANT NEOPLASM PROGRESSION (449 patients)
FEBRILE NEUTROPENIA (446 patients)
ARTHRALGIA (439 patients)
HYPONATRAEMIA (436 patients)
HYPERTENSION (432 patients)
DEEP VEIN THROMBOSIS (431 patients)
BLOOD CREATININE INCREASED (429 patients)
WEIGHT DECREASED (427 patients)
CONFUSIONAL STATE (423 patients)
URINARY TRACT INFECTION (415 patients)
PARAESTHESIA (414 patients)
HYPOKALAEMIA (397 patients)
INJURY (388 patients)
DRUG INEFFECTIVE (375 patients)
CARDIAC FAILURE CONGESTIVE (372 patients)
CARDIAC FAILURE (372 patients)
CELLULITIS (370 patients)
COUGH (369 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (368 patients)
ORTHOSTATIC HYPOTENSION (361 patients)
ATELECTASIS (361 patients)
SYNCOPE (359 patients)
HYPOXIA (358 patients)
HEADACHE (355 patients)
LEUKOPENIA (350 patients)
PAIN IN JAW (350 patients)
BRONCHITIS (345 patients)
TOOTH EXTRACTION (340 patients)
MALAISE (339 patients)
SEPTIC SHOCK (339 patients)
OSTEOMYELITIS (335 patients)
PULMONARY OEDEMA (323 patients)
TUMOUR LYSIS SYNDROME (318 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (317 patients)
PULMONARY EMBOLISM (310 patients)
MUSCULAR WEAKNESS (308 patients)
DEPRESSION (301 patients)
LUNG DISORDER (299 patients)
IMPAIRED HEALING (297 patients)
CHILLS (294 patients)
SPINAL OSTEOARTHRITIS (294 patients)
INTERSTITIAL LUNG DISEASE (284 patients)
CONDITION AGGRAVATED (282 patients)
HYPERCALCAEMIA (280 patients)
TACHYCARDIA (274 patients)
ALANINE AMINOTRANSFERASE INCREASED (272 patients)
OSTEOARTHRITIS (269 patients)
DYSPHAGIA (267 patients)
OEDEMA (267 patients)
MUCOSAL INFLAMMATION (261 patients)
HYPERGLYCAEMIA (259 patients)
NEUTROPHIL COUNT DECREASED (257 patients)
CARDIOMEGALY (254 patients)
MULTI-ORGAN FAILURE (252 patients)
BONE PAIN (249 patients)
GASTROINTESTINAL HAEMORRHAGE (247 patients)
STAPHYLOCOCCAL INFECTION (245 patients)
SOMNOLENCE (243 patients)
BONE LESION (231 patients)
ERYTHEMA (231 patients)
INSOMNIA (230 patients)
LUNG INFILTRATION (230 patients)
OSTEOPOROSIS (228 patients)
MYOCARDIAL INFARCTION (227 patients)
UPPER RESPIRATORY TRACT INFECTION (226 patients)
INTERVERTEBRAL DISC DEGENERATION (221 patients)
SWELLING (219 patients)
HAEMATOCRIT DECREASED (219 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (218 patients)
PLASMACYTOMA (214 patients)
STEM CELL TRANSPLANT (213 patients)
EMOTIONAL DISTRESS (212 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (212 patients)
RENAL FAILURE CHRONIC (211 patients)
MENTAL STATUS CHANGES (211 patients)
C-REACTIVE PROTEIN INCREASED (210 patients)
VISION BLURRED (209 patients)
SINUSITIS (209 patients)
MYALGIA (208 patients)
BLOOD UREA INCREASED (203 patients)
CATARACT (203 patients)
ABDOMINAL DISTENSION (201 patients)
RENAL IMPAIRMENT (199 patients)
LOSS OF CONSCIOUSNESS (198 patients)
HYPOCALCAEMIA (198 patients)
OSTEOPENIA (194 patients)
CONVULSION (193 patients)
COLITIS (193 patients)
HYPERKALAEMIA (192 patients)
NEOPLASM MALIGNANT (189 patients)
CARDIAC ARREST (188 patients)
POLYNEUROPATHY (188 patients)
ANOREXIA (188 patients)
ANHEDONIA (186 patients)
PULMONARY HYPERTENSION (185 patients)
TREMOR (184 patients)
DEFORMITY (184 patients)
GAIT DISTURBANCE (181 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (178 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (174 patients)
COMPRESSION FRACTURE (172 patients)
DYSPEPSIA (172 patients)
INTERVERTEBRAL DISC PROTRUSION (170 patients)
BONE MARROW FAILURE (169 patients)
EPISTAXIS (168 patients)
ACUTE RESPIRATORY DISTRESS SYNDROME (168 patients)
HEPATIC FUNCTION ABNORMAL (168 patients)
RESPIRATORY DISTRESS (167 patients)
GASTRITIS (165 patients)
INFLAMMATION (165 patients)
MITRAL VALVE INCOMPETENCE (164 patients)
DYSPNOEA EXERTIONAL (163 patients)
NEUROPATHY (162 patients)
CORONARY ARTERY DISEASE (162 patients)
NEURALGIA (162 patients)
RIB FRACTURE (162 patients)
MUSCULOSKELETAL PAIN (159 patients)
SPINAL COMPRESSION FRACTURE (157 patients)
ILEUS (157 patients)
URINARY RETENTION (157 patients)
CEREBRAL HAEMORRHAGE (156 patients)
DENTAL CARIES (156 patients)
DECREASED INTEREST (155 patients)
ABDOMINAL PAIN UPPER (153 patients)
ASTHMA (153 patients)
PNEUMONITIS (151 patients)
OSTEOLYSIS (151 patients)
DIABETES MELLITUS (149 patients)
HAEMORRHAGE (148 patients)
HYPOPHOSPHATAEMIA (147 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (147 patients)
BLOOD CALCIUM DECREASED (146 patients)
EJECTION FRACTION DECREASED (145 patients)
INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION (145 patients)
MUSCLE SPASMS (143 patients)
HAEMATURIA (143 patients)
DIVERTICULUM (142 patients)
CEREBROVASCULAR ACCIDENT (141 patients)
OFF LABEL USE (141 patients)
HYPOPHAGIA (139 patients)
NO THERAPEUTIC RESPONSE (138 patients)
SWELLING FACE (138 patients)
CLOSTRIDIUM DIFFICILE COLITIS (138 patients)
EXOSTOSIS (137 patients)
HIATUS HERNIA (137 patients)
LIVER DISORDER (137 patients)
CARDIOMYOPATHY (136 patients)
RECTAL HAEMORRHAGE (135 patients)
DIALYSIS (135 patients)
BLOOD SODIUM DECREASED (134 patients)
ILEUS PARALYTIC (133 patients)
PERIPHERAL SENSORY NEUROPATHY (133 patients)
WEIGHT INCREASED (133 patients)
DRUG TOXICITY (132 patients)
BLOOD GLUCOSE INCREASED (132 patients)
HYPOALBUMINAEMIA (131 patients)
PRODUCTIVE COUGH (131 patients)
BLOOD POTASSIUM DECREASED (131 patients)
FLUID OVERLOAD (128 patients)
THROMBOSIS (128 patients)
LOWER RESPIRATORY TRACT INFECTION (126 patients)
HAEMORRHOIDS (126 patients)
ARRHYTHMIA (126 patients)
PATHOLOGICAL FRACTURE (125 patients)

In addition to reviewing our up-to-date FDA research, users may interact with the FactMed community - currently one million members and growing! FactMed online research and discussions are read by patients, scientists, physicians, and other interested health care parties. Post follow up Questions to learn from our diverse readership. Likewise, patients who have experienced unwanted effects are encouraged to share their Concerns to help educate and inform our members.

Recent FactMed Activity for VELCADE

Issue	Description / Topic	Timestamp
QUESTION PSORIASIS	I am taking velcade for multiple myeloma, all of a sudden I have psoriasis on my scalp, extremely itchy, really bad, dr just gave me a prescription shampoo, is this common, I am also on cytoxen and dex, thank you, my email is taxm1040@aol.com	2014-12-06 01:46:59
QUESTION PSORIASIS	I am taking velcade for multiple myeloma, all of a sudden I have psoriasis on my scalp, extremely itchy, really bad, dr just gave me a prescription shampoo, is this common, I am also on cytoxen and dex, thank you, my email is taxm1040@aol.com	2014-12-06 01:48:46
QUESTION SINUS TACHYCARDIA	I received 2 regimens of chemotherapy in 2008/2009. Velcade/cytoxin year 1 and velcade /doxyl year 2 followed by autologous stem cell rescue. I've been in remission since March 2010 but suffer with acute peripheral neuropathy and tachycardia which is most likely due to the velcade regimen. What percentage of Velcade treated MM have this neuropathy combination?	2014-12-17 15:54:34
QUESTION ISCHAEMIC STROKE	Can velcade cause a stroke? After my latest injection of sub-Q velcade, I developed a fever (as I have after every injection), and woke up the morning the Saturday morning after a Wednesday treatment to find my legs were numb and I had balance problems (this was almost three weeks ago, and the symptoms have not subsided). I attributed the neuropathy to the velcade, but when I saw my oncologist the following Thursday, he said the symptoms were not typical of velcade neuropathy. He didn't specify a cause for my condition, however, as I am also being treated for a thoracic tumor, and he said that might be the source of the problem. (I'm skeptical as the changes came on so suddenly, overnight.). Please enlighten me.	2016-02-10 12:47:46
QUESTION CHRONIC FATIGUE SYNDROME	wife eskd due to suspected monoclonal gammopathy renal significant dr (hematologist ) prescribed subcut velcade injection every two weeks 8 mos later she is exhibiting several od velcade's side effects worst being chronic fatigue and gastric problems just curious if anyone else diagnosed with monoclonal gammopathy she also says NO MORE velcade	2016-04-16 21:37:11
CONCERN ELECTROCARDIOGRAM T WAVE INVERSION	My mother, 80 yr old. Dx: Primary Amyloidosis. No history of heart disease or dysfunction. After about 8 weeks of Velcade developed severe bradycardia with eventual stage II heart blockage, T-Wave inversion which lead to a dual chamber pace maker. It took me researching this info to realize it was he Velcade. After much arguing with the health care provider, she is now off Velcade. Questions/comments: LeezaAnn63@hotmail.com	2016-05-29 13:34:51
QUESTION ABDOMINAL HERNIA	I take velcade injections in my abdomen and have developed five hernias could getting the injections in my abdomen cause this	2016-07-29 23:36:28

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