About this FactMed analysis covering adverse side effect reports of ACENOCOUMAROL patients who developed AKINESIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 1 individuals taking ACENOCOUMAROL reported AKINESIA to the FDA. A total of 1453 ACENOCOUMAROL drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between ACENOCOUMAROL and AKINESIA. In doing so, we compare ACENOCOUMAROL with other drugs that cause AKINESIA, to help you evaluate whether or not ACENOCOUMAROL causes AKINESIA. Likewise, this page shows the most highly-reported side effects of ACENOCOUMAROL, so you can see if AKINESIA ranks among ACENOCOUMAROL's most well-known side effects.
Summary Statistics
Reports of ACENOCOUMAROL causing AKINESIA: 1
Reports of any side effect of ACENOCOUMAROL : 1453
Percentage of ACENOCOUMAROL patients where AKINESIA is a reported side effect: 0.0688%

FDA reports of any drug causing AKINESIA : 753
Average percentage for all medicated patients where AKINESIA is reported as a complication: 0.0047%

Physician opinion on ACENOCOUMAROL as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing ACENOCOUMAROL:
ATRIAL FIBRILLATION ( 139 patients )
DRUG USE FOR UNKNOWN INDICATION ( 104 patients )
ANTICOAGULANT THERAPY ( 64 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 47 patients )
PROPHYLAXIS ( 41 patients )
PULMONARY EMBOLISM ( 28 patients )
THROMBOSIS PROPHYLAXIS ( 28 patients )
THROMBOSIS ( 22 patients )
DEEP VEIN THROMBOSIS ( 17 patients )
CARDIAC FAILURE ( 15 patients )
ARRHYTHMIA ( 14 patients )
ATRIAL FLUTTER ( 14 patients )
COAGULOPATHY ( 7 patients )
CEREBROVASCULAR ACCIDENT ( 6 patients )
CARDIAC ANEURYSM ( 6 patients )
HEART VALVE REPLACEMENT ( 6 patients )
OVERDOSE ( 5 patients )
CARDIAC FAILURE CONGESTIVE ( 5 patients )
CORONARY ARTERY DISEASE ( 4 patients )
CARDIAC VALVE DISEASE ( 3 patients )
ILL-DEFINED DISORDER ( 3 patients )
MITRAL VALVE INCOMPETENCE ( 3 patients )
MYELOPROLIFERATIVE DISORDER ( 3 patients )
EMBOLISM ( 3 patients )
CEREBRAL ATHEROSCLEROSIS ( 3 patients )
MITRAL VALVE REPLACEMENT ( 3 patients )
VASCULAR OCCLUSION ( 3 patients )
CARDIAC DISORDER ( 3 patients )
CARDIOMYOPATHY ( 2 patients )
CHEST PAIN ( 2 patients )
VENA CAVA THROMBOSIS ( 2 patients )
VENTRICULAR DYSFUNCTION ( 2 patients )
CARDIAC VALVE PROSTHESIS USER ( 2 patients )
INTERNATIONAL NORMALISED RATIO ( 2 patients )
AORTIC VALVE REPLACEMENT ( 2 patients )
KNEE ARTHROPLASTY ( 2 patients )
MULTIPLE DRUG OVERDOSE ( 2 patients )
VENOUS THROMBOSIS ( 2 patients )
MYOCARDIAL ISCHAEMIA ( 2 patients )
CARDIAC FLUTTER ( 1 patients )
EMBOLISM ARTERIAL ( 1 patients )
PULMONARY ARTERIAL PRESSURE ( 1 patients )
TACHYARRHYTHMIA ( 1 patients )
INTRACARDIAC THROMBUS ( 1 patients )
TRANSIENT ISCHAEMIC ATTACK ( 1 patients )
MITRAL VALVE STENOSIS ( 1 patients )
DISEASE RECURRENCE ( 1 patients )
CARDIAC FIBRILLATION ( 1 patients )
POSTOPERATIVE THROMBOSIS ( 1 patients )
CARDIAC PACEMAKER INSERTION ( 1 patients )
ACUTE MYOCARDIAL INFARCTION ( 1 patients )
TAKAYASU'S ARTERITIS ( 1 patients )
CEREBROVASCULAR ACCIDENT PROPHYLAXIS ( 1 patients )
COAGULATION TIME PROLONGED ( 1 patients )
BLOOD DISORDER ( 1 patients )
CONGENITAL HEART VALVE DISORDER ( 1 patients )
VENTRICULAR SEPTAL DEFECT ( 1 patients )
PHLEBITIS ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with AKINESIA:

MODOPAR (292 patients)
EFFEXOR (145 patients)
XANAX (129 patients)
VIOXX (116 patients)
STALEVO 100 (111 patients)
ASPIRIN (73 patients)
PERGOLIDE MESYLATE (56 patients)
SINEMET (55 patients)
RISPERDAL (54 patients)
ATHYMIL (52 patients)
COMTAN (45 patients)
MADOPAR (41 patients)
LORAZEPAM (40 patients)
MADOPAR DISPERSIBLE (39 patients)
IMOVANE (38 patients)
ZYPREXA (37 patients)
ATARAX (37 patients)
VALPROATE SODIUM (36 patients)
CLOZAPINE (31 patients)
DEPAKOTE (30 patients)
CITALOPRAM HYDROBROMIDE (29 patients)
CLOBAZAM (29 patients)
FUROSEMIDE (28 patients)
REQUIP (28 patients)
PARLODEL (27 patients)
EXELON (27 patients)
PAXIL (26 patients)
DIGOXIN (25 patients)
LASIX (25 patients)
ERYTHROMYCIN (25 patients)
SEROQUEL (25 patients)
LAMOTRIGINE (25 patients)
RISPERIDONE (24 patients)
GENTAMICIN (24 patients)
PHENYTOIN (23 patients)
AMANTADINE HCL (23 patients)
ACETAMINOPHEN (21 patients)
HALDOL (21 patients)
DIAZEPAM (20 patients)
VALTREX (20 patients)
OMEPRAZOLE (19 patients)
PAROXETINE HCL (19 patients)
ACETAMINOPHEN AND TRAMADOL HCL (18 patients)
CEFOTAXIME (18 patients)
SPIRONOLACTONE (18 patients)
LEVOTHYROXINE SODIUM (18 patients)
TEGRETOL (17 patients)
PREDNISOLONE (17 patients)
DEPAKENE (17 patients)
HALOPERIDOL (17 patients)
SIMVASTATIN (16 patients)
NITROGLYCERIN (16 patients)
ZOLOFT (15 patients)
PIPERACILLIN (15 patients)
LIPITOR (15 patients)
LEXOMIL (14 patients)
CLOPIDOGREL (14 patients)
OLANZAPINE (14 patients)
CABERGOLINE (14 patients)
TEMESTA (14 patients)
CLONAZEPAM (14 patients)
IBUPROFEN (14 patients)
NEURONTIN (13 patients)
LEVODOPA (13 patients)
WARFARIN SODIUM (13 patients)
SERENACE (13 patients)
OXYCONTIN (13 patients)
MEMANTINE HCL (13 patients)
ATENOLOL (13 patients)
DIOVAN (12 patients)
HIZENTRA (12 patients)
PRAMIPEXOLE DIHYDROCHLORIDE (12 patients)
ALBUTEROL (12 patients)
CELEBREX (12 patients)
HEPARIN (12 patients)
SEROQUEL XR (12 patients)
ENOXAPARIN SODIUM (12 patients)
ATORVASTATIN CALCIUM (12 patients)
ABILIFY (11 patients)
PLAVIX (11 patients)
FLUOXETINE (11 patients)
LOXAPINE HCL (11 patients)
COREG (11 patients)
TAXOTERE (11 patients)
GLEEVEC (11 patients)
VENLAFAXINE (11 patients)
PREVACID (11 patients)
CAPTOPRIL (11 patients)
CIPRO (11 patients)
CYCLOSPORINE (11 patients)
LANTUS (10 patients)
SYNTHROID (10 patients)
ACTONEL (10 patients)
MIRAPEX (10 patients)
KETOCONAZOLE (10 patients)
ANTIBIOTICS (10 patients)
ARICEPT (10 patients)
HEPARIN SODIUM INJECTION (10 patients)
AVONEX (10 patients)
RAMIPRIL (9 patients)
INSULIN (9 patients)
NECYRANE (9 patients)
MORPHINE (9 patients)
FERROUS SULFATE TAB (9 patients)
PRAZEPAM (9 patients)
DONEPEZIL HCL (9 patients)
CARBOCISTEINE (9 patients)
EXTAVIA (9 patients)
BROMOCRIPTINE MESYLATE (9 patients)
AMBIEN (9 patients)
AMOXICILLIN (9 patients)
RISPERDAL CONSTA (9 patients)
LAMICTAL (9 patients)
SINGULAIR (9 patients)
ECONAZOLE NITRATE (9 patients)
ARTANE (9 patients)
FOLIC ACID (9 patients)
PRAMIPEXOLE DIHYCHLLORIDE (9 patients)
LISINOPRIL (9 patients)
CEFUROXIME (9 patients)
LYSOPAINE (9 patients)
PRILOSEC (9 patients)
HYDROCHLOROTHIAZIDE (9 patients)
SANDIMMUNE (9 patients)
CYMBALTA (8 patients)
ELUDRIL (8 patients)
MIRTAZAPINE (8 patients)
SOLANAX (8 patients)
EPINEPHRINE (8 patients)
TYLENOL (CAPLET) (8 patients)
CIATYL Z (8 patients)
TRAMAL (8 patients)
AMIODARONE HCL (8 patients)
COUMADIN (8 patients)
NEUROCIL (8 patients)
OXAZEPAM (8 patients)
LEVEMIR (8 patients)
AVANDIA (8 patients)
NEXIUM (8 patients)
PROTONIX (8 patients)
ZOCOR (8 patients)
WELLBUTRIN (8 patients)
BIPERIDEN HYDROCHLORIDE TAB (8 patients)
METFORMIN HCL (7 patients)
NORVASC (7 patients)
METOPROLOL (7 patients)
TRIVASTAL (7 patients)
ZANAFLEX (7 patients)
HUMIRA (7 patients)
ALDACTONE (7 patients)
SOLU-CORTEF (7 patients)
ALLOPURINOL (7 patients)
TRIHEXYPHENIDYL HCL (7 patients)
PREVISCAN (7 patients)
DOPAMINE HCL (7 patients)
SERTRALINE HCL (7 patients)
THIOPENTAL SODIUM (7 patients)
ENALAPRIL MALEATE (7 patients)
BISOPROLOL FUMARATE (7 patients)
TRAZODONE HCL (7 patients)
LITHIUM CARBONATE (7 patients)
TYLENOL (7 patients)
TRANXENE (7 patients)
POTASSIUM CHLORIDE (7 patients)
CEFOTAXIME SODIUM (7 patients)
PREDONINE (7 patients)
ISOSORBIDE DINITRATE (7 patients)
CYTARABINE (7 patients)
VITAMIN D (7 patients)
CARBIDOPA AND LEVODOPA (6 patients)
LOVENOX (6 patients)
ACETYLSALICYLIC ACID SRT (6 patients)
ESCITALOPRAM (6 patients)
DEXAMETHASONE TAB (6 patients)
SERTRALINE HYDROCHLORIDE (6 patients)
EVEROLIMUS (6 patients)
TASMAR (6 patients)
ALPRAZOLAM (6 patients)
MANTADIX (6 patients)
PRAZINE (6 patients)
HERCEPTIN (6 patients)
DEROXAT (6 patients)
AMLODIPINE (6 patients)
METHYLPREDNISOLONE (6 patients)
PURSENNID (6 patients)
REMICADE (6 patients)
SILECE (6 patients)
ZOVIRAX (6 patients)
MYCOPHENOLATE MOFETIL (6 patients)
ARAVA (6 patients)
LEPTICUR (6 patients)
CARBAMAZEPINE (6 patients)
TOBRAMYCIN (6 patients)
SYMMETREL (6 patients)
ATIVAN (6 patients)
ATORVASTATIN (6 patients)
CIPRALEX (ESCITALOPRAM) (6 patients)
LYRICA (6 patients)
CLARITHROMYCIN (6 patients)
CITALOPRAM (6 patients)
VANCOMYCIN (6 patients)
HEPTAMINOL (6 patients)
AZILECT (6 patients)
HUMALOG (6 patients)
PREDNISONE TAB (6 patients)
PROPRANOLOL (6 patients)
PROCTOLOG (6 patients)
INTETRIX (6 patients)
RANITIDINE (6 patients)
MS CONTIN (5 patients)
Most common side effects for patients taking ACENOCOUMAROL:
DRUG INTERACTION (199 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (116 patients)
CARDIAC FAILURE (91 patients)
ANAEMIA (78 patients)
FALL (68 patients)
RENAL FAILURE (61 patients)
VOMITING (53 patients)
ATRIAL FIBRILLATION (53 patients)
FATIGUE (53 patients)
DIZZINESS (51 patients)
RENAL FAILURE ACUTE (49 patients)
DYSPNOEA (49 patients)
PYREXIA (48 patients)
HAEMATOMA (46 patients)
NAUSEA (44 patients)
HYPOTENSION (43 patients)
DEATH (43 patients)
MALAISE (41 patients)
HAEMOGLOBIN DECREASED (40 patients)
PULMONARY EMBOLISM (39 patients)
DIARRHOEA (38 patients)
OVERDOSE (38 patients)
CARDIOGENIC SHOCK (38 patients)
ARRHYTHMIA (36 patients)
PNEUMONIA (35 patients)
GASTROINTESTINAL HAEMORRHAGE (35 patients)
DRUG INEFFECTIVE (34 patients)
ASTHENIA (32 patients)
HYPERKALAEMIA (32 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (30 patients)
SYNCOPE (28 patients)
LOSS OF CONSCIOUSNESS (27 patients)
OEDEMA PERIPHERAL (27 patients)
BLOOD CREATININE INCREASED (26 patients)
PROTHROMBIN TIME PROLONGED (23 patients)
THROMBOSIS (23 patients)
BRADYCARDIA (23 patients)
WEIGHT DECREASED (23 patients)
DISORIENTATION (22 patients)
HAEMATURIA (22 patients)
CONSTIPATION (22 patients)
RHABDOMYOLYSIS (21 patients)
CONFUSIONAL STATE (21 patients)
PLEURAL EFFUSION (21 patients)
HYPONATRAEMIA (20 patients)
MELAENA (20 patients)
ABDOMINAL PAIN (19 patients)
DEHYDRATION (19 patients)
HEPATIC FAILURE (19 patients)
SOMNOLENCE (19 patients)
PALLOR (19 patients)
MYOCARDIAL INFARCTION (19 patients)
THROMBOCYTOPENIA (18 patients)
PAIN (18 patients)
VENTRICULAR FIBRILLATION (18 patients)
HEADACHE (17 patients)
ISCHAEMIC STROKE (17 patients)
EPISTAXIS (17 patients)
RENAL IMPAIRMENT (17 patients)
HYPOGLYCAEMIA (16 patients)
CHEST PAIN (16 patients)
HAEMOPTYSIS (16 patients)
HEPATOTOXICITY (16 patients)
DIPLOPIA (16 patients)
SEPTIC SHOCK (16 patients)
VENTRICULAR TACHYCARDIA (16 patients)
HAEMORRHAGE (16 patients)
STAPHYLOCOCCAL INFECTION (16 patients)
VENTRICULAR ARRHYTHMIA (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
CONVULSION (15 patients)
BLOOD GLUCOSE INCREASED (15 patients)
HAEMATEMESIS (15 patients)
COUGH (15 patients)
ALANINE AMINOTRANSFERASE INCREASED (14 patients)
FEBRILE NEUTROPENIA (14 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (14 patients)
DELIRIUM (14 patients)
COAGULOPATHY (14 patients)
MUSCULAR WEAKNESS (14 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (14 patients)
ELECTROCARDIOGRAM QT PROLONGED (14 patients)
PARAESTHESIA (14 patients)
LACTIC ACIDOSIS (14 patients)
HYPERHIDROSIS (14 patients)
CARDIO-RESPIRATORY ARREST (14 patients)
CEREBROVASCULAR ACCIDENT (13 patients)
SUBDURAL HAEMATOMA (13 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (13 patients)
CONDITION AGGRAVATED (13 patients)
RESPIRATORY FAILURE (13 patients)
CONCOMITANT DISEASE PROGRESSION (13 patients)
RESPIRATORY TRACT INFECTION (12 patients)
ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED (12 patients)
INTERNATIONAL NORMALISED RATIO DECREASED (12 patients)
HALLUCINATION (12 patients)
PULMONARY OEDEMA (12 patients)
DECREASED APPETITE (12 patients)
HEPATIC ENZYME INCREASED (12 patients)
WEIGHT INCREASED (12 patients)
DRUG TOXICITY (11 patients)
TACHYCARDIA (11 patients)
TREMOR (11 patients)
DYSURIA (11 patients)
ATRIOVENTRICULAR BLOCK (11 patients)
HYPERGLYCAEMIA (11 patients)
NEOPLASM MALIGNANT (11 patients)
DEMENTIA (11 patients)
SUDDEN DEATH (11 patients)
BLOOD UREA INCREASED (11 patients)
CONTUSION (11 patients)
SEPSIS (11 patients)
CARDIAC ARREST (11 patients)
CARDIAC FAILURE CONGESTIVE (11 patients)
MYALGIA (11 patients)
THERAPEUTIC AGENT TOXICITY (11 patients)
INTERSTITIAL LUNG DISEASE (10 patients)
ABDOMINAL PAIN UPPER (10 patients)
TUBERCULOSIS (10 patients)
SPEECH DISORDER (10 patients)
LIVER INJURY (10 patients)
MALIGNANT NEOPLASM OF AMPULLA OF VATER (10 patients)
DEEP VEIN THROMBOSIS (10 patients)
LOWER LIMB FRACTURE (10 patients)
LEUKOCYTOSIS (10 patients)
BLOOD PRESSURE INCREASED (10 patients)
ELECTROCARDIOGRAM QRS COMPLEX PROLONGED (10 patients)
TOXIC SKIN ERUPTION (10 patients)
RASH (10 patients)
LIVER DISORDER (10 patients)
GAIT DISTURBANCE (9 patients)
DISEASE PROGRESSION (9 patients)
RENAL FAILURE CHRONIC (9 patients)
ARTHRALGIA (9 patients)
HYPERTENSION (9 patients)
BACK PAIN (9 patients)
FEMUR FRACTURE (9 patients)
HYPOKALAEMIA (9 patients)
ILEUS (9 patients)
STATUS EPILEPTICUS (9 patients)
SUPRAVENTRICULAR TACHYCARDIA (9 patients)
HALLUCINATION, VISUAL (9 patients)
HEART RATE DECREASED (9 patients)
C-REACTIVE PROTEIN INCREASED (9 patients)
PARKINSONISM (8 patients)
ACUTE PULMONARY OEDEMA (8 patients)
MUSCLE SPASMS (8 patients)
LUNG DISORDER (8 patients)
HAEMODYNAMIC INSTABILITY (8 patients)
ANGINA PECTORIS (8 patients)
HYPOMAGNESAEMIA (8 patients)
ANXIETY (8 patients)
LEUKOPENIA (8 patients)
CORONARY ARTERY DISEASE (8 patients)
DEPRESSION (8 patients)
FLUID OVERLOAD (8 patients)
SHOCK (8 patients)
NEUROLOGICAL SYMPTOM (8 patients)
SKIN LESION (8 patients)
INFANTILE SPITTING UP (8 patients)
INFECTION (8 patients)
DYSPHAGIA (8 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (8 patients)
PANCYTOPENIA (8 patients)
CAROTID ARTERY STENOSIS (8 patients)
VISION BLURRED (8 patients)
VISUAL ACUITY REDUCED (8 patients)
RECTAL HAEMORRHAGE (8 patients)
TORSADE DE POINTES (8 patients)
CARDIAC DISORDER (8 patients)
CARDIOMEGALY (8 patients)
EOSINOPHILIA (7 patients)
PAIN IN EXTREMITY (7 patients)
HEART RATE IRREGULAR (7 patients)
STOMATITIS (7 patients)
ACUTE MYOCARDIAL INFARCTION (7 patients)
INTERNATIONAL NORMALISED RATIO ABNORMAL (7 patients)
ALOPECIA (7 patients)
GASTROENTERITIS (7 patients)
DRY MOUTH (7 patients)
APHASIA (7 patients)
TOXICITY TO VARIOUS AGENTS (7 patients)
HYPERSENSITIVITY (7 patients)
SKIN NECROSIS (7 patients)
FRACTURE (7 patients)
BLOOD BILIRUBIN INCREASED (7 patients)
DRUG EXPOSURE DURING PREGNANCY (7 patients)
INSOMNIA (7 patients)
OSTEOMYELITIS (7 patients)
CHOLESTASIS (7 patients)
TRANSIENT ISCHAEMIC ATTACK (7 patients)
VERTIGO (7 patients)
PRURITUS (7 patients)
MEDICATION ERROR (7 patients)
ERYTHEMA (7 patients)
PLATELET COUNT INCREASED (7 patients)
HYPOCALCAEMIA (7 patients)
HYPERTHYROIDISM (6 patients)
ACUTE RESPIRATORY FAILURE (6 patients)
SKIN DISCOLOURATION (6 patients)
NEUROPATHY PERIPHERAL (6 patients)
EYE PAIN (6 patients)
SKIN EXFOLIATION (6 patients)
BLADDER CANCER (6 patients)
IMPAIRED HEALING (6 patients)
BLOOD CALCIUM DECREASED (6 patients)
ERYTHEMA MULTIFORME (6 patients)
FAECAL INCONTINENCE (6 patients)
CARDIAC TAMPONADE (6 patients)
CARDIOACTIVE DRUG LEVEL INCREASED (6 patients)

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Recent FactMed Activity for ACENOCOUMAROL


Issue Description / Topic Timestamp
QUESTION
GENERAL ANAESTHESIA
Can I safely administer general anesthesia or spinal anesthesia to a patient with Dacron abdominal aortic prosthesis who received Acenocoumarol , NSAIDs and aspirin until 2 days ago ? His INR is now 1,6. 2014-12-04 06:01:43

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