About this FactMed analysis covering adverse side effect reports of ALDACTAZIDE patients who developed POLYNEUROPATHY.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 2 individuals taking ALDACTAZIDE reported POLYNEUROPATHY to the FDA. A total of 517 ALDACTAZIDE drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between ALDACTAZIDE and POLYNEUROPATHY. In doing so, we compare ALDACTAZIDE with other drugs that cause POLYNEUROPATHY, to help you evaluate whether or not ALDACTAZIDE causes POLYNEUROPATHY. Likewise, this page shows the most highly-reported side effects of ALDACTAZIDE, so you can see if POLYNEUROPATHY ranks among ALDACTAZIDE's most well-known side effects.
Summary Statistics
Reports of ALDACTAZIDE causing POLYNEUROPATHY: 2
Reports of any side effect of ALDACTAZIDE : 517
Percentage of ALDACTAZIDE patients where POLYNEUROPATHY is a reported side effect: 0.3868%

FDA reports of any drug causing POLYNEUROPATHY : 3015
Average percentage for all medicated patients where POLYNEUROPATHY is reported as a complication: 0.0189%

Physician opinion on ALDACTAZIDE as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing ALDACTAZIDE:
HYPERTENSION ( 73 patients )
DRUG USE FOR UNKNOWN INDICATION ( 18 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 11 patients )
ILL-DEFINED DISORDER ( 8 patients )
OEDEMA PERIPHERAL ( 7 patients )
BLOOD PRESSURE ( 6 patients )
ESSENTIAL HYPERTENSION ( 5 patients )
CARDIAC DISORDER ( 4 patients )
DIURETIC THERAPY ( 4 patients )
OEDEMA ( 3 patients )
SWELLING ( 3 patients )
FLUID RETENTION ( 2 patients )
CARDIAC FAILURE CHRONIC ( 2 patients )
RHEUMATOID ARTHRITIS ( 1 patients )
BLOOD PRESSURE FLUCTUATION ( 1 patients )
TYPE 2 DIABETES MELLITUS ( 1 patients )
CARDIAC FAILURE ( 1 patients )
DIURETIC EFFECT ( 1 patients )
HYPERTENSIVE CARDIOMYOPATHY ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with POLYNEUROPATHY:

SEROQUEL (377 patients)
FOSAMAX (265 patients)
ASPIRIN (217 patients)
VIOXX (210 patients)
VELCADE (188 patients)
ZOMETA (180 patients)
NEURONTIN (179 patients)
DEXAMETHASONE (172 patients)
METHOTREXATE (162 patients)
PREDNISOLONE (156 patients)
HUMIRA (145 patients)
PREDNISONE (140 patients)
LASIX (125 patients)
LYRICA (125 patients)
REMICADE (120 patients)
CYCLOPHOSPHAMIDE (119 patients)
NEXIUM (117 patients)
FOLIC ACID (112 patients)
AREDIA (110 patients)
SIMVASTATIN (109 patients)
LEVOTHYROXINE SODIUM (106 patients)
ALLOPURINOL (93 patients)
ZOCOR (92 patients)
LIPITOR (92 patients)
XANAX (91 patients)
PRILOSEC (90 patients)
OMEPRAZOLE (87 patients)
LEVAQUIN (79 patients)
SYNTHROID (79 patients)
COUMADIN (78 patients)
PROTONIX (77 patients)
THALIDOMIDE (77 patients)
DOXORUBICIN HCL (76 patients)
FUROSEMIDE (75 patients)
ENBREL (75 patients)
DIAZEPAM (72 patients)
VICODIN (68 patients)
LORAZEPAM (68 patients)
ZYPREXA (68 patients)
HYDROCHLOROTHIAZIDE (67 patients)
REVLIMID (67 patients)
CYMBALTA (66 patients)
VINCRISTINE (66 patients)
LISINOPRIL (64 patients)
ATIVAN (64 patients)
ACETAMINOPHEN (62 patients)
PREDNISONE TAB (62 patients)
MULTI-VITAMINS (60 patients)
ADVAIR DISKUS 100/50 (60 patients)
PLAVIX (60 patients)
AVASTIN (59 patients)
MAGNEVIST (58 patients)
IBUPROFEN (58 patients)
GABAPENTIN (57 patients)
OXYCODONE HCL (57 patients)
CISPLATIN (56 patients)
CLONAZEPAM (56 patients)
METOPROLOL TARTRATE (55 patients)
VALIUM (55 patients)
DIGOXIN (55 patients)
REMERON (54 patients)
TAXOTERE (54 patients)
TAMOXIFEN CITRATE (54 patients)
RAMIPRIL (53 patients)
CELEXA (53 patients)
AVELOX (53 patients)
ETOPOSIDE (52 patients)
INSULIN (52 patients)
CEPHALEXIN (52 patients)
XELODA (51 patients)
MABTHERA (50 patients)
MORPHINE (50 patients)
CYCLOSPORINE (50 patients)
HEPARIN SODIUM INJECTION (49 patients)
RITUXIMAB (49 patients)
ALBUTEROL (49 patients)
ZOLOFT (49 patients)
FLAGYL (48 patients)
LAMICTAL (48 patients)
FLUOROURACIL (47 patients)
SINGULAIR (47 patients)
VITAMIN B-12 (46 patients)
FEMARA (46 patients)
TASIGNA (46 patients)
OXYCONTIN (46 patients)
PEG-INTRON (46 patients)
EFFEXOR XR (46 patients)
COMPAZINE (45 patients)
ATENOLOL (45 patients)
REBETOL (45 patients)
ZOFRAN (45 patients)
NORVASC (44 patients)
WARFARIN SODIUM (44 patients)
TAXOL (44 patients)
PAXIL (44 patients)
KLONOPIN (43 patients)
METRONIDAZOLE (43 patients)
LEVOFLOXACIN (43 patients)
CELEBREX (43 patients)
PANTOPRAZOLE SODIUM (43 patients)
SPIRIVA (43 patients)
CALCIUM (42 patients)
AMBIEN (42 patients)
BONIVA (42 patients)
METOPROLOL (41 patients)
TOPROL-XL (40 patients)
METOPROLOL SUCCINATE (40 patients)
POTASSIUM CHLORIDE (40 patients)
AMLODIPINE (40 patients)
HYDROCORTISONE (39 patients)
GLUCOPHAGE (39 patients)
CIPROFLOXACIN (38 patients)
LIDODERM (38 patients)
METFORMIN HCL (38 patients)
COLACE (37 patients)
PANTOPRAZOLE (37 patients)
BISOPROLOL FUMARATE (37 patients)
CYTOXAN (37 patients)
MIRALAX (37 patients)
FLEXERIL (36 patients)
TRAMADOL HCL (36 patients)
AROMASIN (36 patients)
ATORVASTATIN CALCIUM (36 patients)
METOCLOPRAMIDE (36 patients)
TACROLIMUS (36 patients)
LANTUS (36 patients)
DILAUDID (35 patients)
ALENDRONATE SODIUM (35 patients)
PROCHLORPERAZINE (35 patients)
FENTANYL (35 patients)
GEMZAR (34 patients)
PEGASYS (34 patients)
ACTOS (34 patients)
CRESTOR (34 patients)
ENALAPRIL MALEATE (34 patients)
TRAZODONE HCL (34 patients)
OXALIPLATIN (34 patients)
ZOLPIDEM (34 patients)
FASLODEX (34 patients)
KEPPRA (33 patients)
DEPAKOTE (33 patients)
REGLAN (33 patients)
TEMAZEPAM (33 patients)
VFEND (33 patients)
KALETRA (33 patients)
ARAVA (32 patients)
AZATHIOPRINE (32 patients)
ACYCLOVIR (32 patients)
LORTAB (32 patients)
LEXAPRO (32 patients)
ITRACONAZOLE (32 patients)
WELLBUTRIN (32 patients)
CYTARABINE (32 patients)
VALTREX (32 patients)
CARBOPLATIN (31 patients)
SULFASALAZINE (31 patients)
NYSTATIN (31 patients)
COZAAR (31 patients)
EFFEXOR (31 patients)
LESCOL (31 patients)
METHYLPREDNISOLONE (30 patients)
MIRTAZAPINE (30 patients)
THALOMID (30 patients)
FLUCONAZOLE (30 patients)
AMOXICILLIN (30 patients)
DEXAMETHASONE TAB (30 patients)
LACTULOSE (29 patients)
RIBAVIRIN (29 patients)
PENICILLIN ^GRUNENTHAL^ (29 patients)
DOXYCYCLINE (29 patients)
CHLORHEXIDINE GLUCONATE (29 patients)
HYDROXYZINE (29 patients)
CYCLOBENZAPRINE (29 patients)
INFLIXIMAB (28 patients)
ACETAMINOPHEN AND HYDROCODONE BITARTRATE (28 patients)
TOPAMAX (28 patients)
AMITRIPTYLINE HCL (28 patients)
HEPARIN SODIUM (28 patients)
ZITHROMAX (28 patients)
ATACAND (27 patients)
HERCEPTIN (27 patients)
TRICOR (27 patients)
OXYCODONE (27 patients)
DIFLUCAN (27 patients)
HUMALOG (26 patients)
DURAGESIC-100 (26 patients)
PROPRANOLOL (26 patients)
COTRIM (26 patients)
PERCOCET (26 patients)
POTASSIUM (26 patients)
RISPERDAL (26 patients)
TEGRETOL (26 patients)
CLONIDINE (26 patients)
AMARYL (26 patients)
VITAMIN B6 (26 patients)
AMIODARONE HCL (26 patients)
ZOLADEX (26 patients)
ZYVOX (26 patients)
VORICONAZOLE (25 patients)
PREVACID (25 patients)
ARIMIDEX (25 patients)
DOCETAXEL (25 patients)
SOLU-MEDROL (25 patients)
TYLENOL (CAPLET) (25 patients)
PREMPRO (25 patients)
NASACORT (25 patients)
NEULASTA (25 patients)
TORSEMIDE (25 patients)
MICARDIS (24 patients)
IRON (24 patients)
Most common side effects for patients taking ALDACTAZIDE:
FALL (42 patients)
DYSPNOEA (38 patients)
OEDEMA PERIPHERAL (36 patients)
RENAL FAILURE (36 patients)
ASTHENIA (34 patients)
RENAL FAILURE ACUTE (32 patients)
CHEST PAIN (30 patients)
PAIN IN EXTREMITY (29 patients)
CONFUSIONAL STATE (28 patients)
PAIN (28 patients)
DIARRHOEA (27 patients)
DIZZINESS (27 patients)
BACK PAIN (26 patients)
NAUSEA (26 patients)
MYOCARDIAL INFARCTION (25 patients)
DRUG INEFFECTIVE (25 patients)
HYPONATRAEMIA (25 patients)
CARDIAC FAILURE (25 patients)
FATIGUE (22 patients)
ANXIETY (22 patients)
VOMITING (22 patients)
CARDIAC FAILURE CONGESTIVE (22 patients)
DEPRESSION (21 patients)
ARTHRALGIA (20 patients)
CELLULITIS (19 patients)
HYPERKALAEMIA (18 patients)
NEUROPATHY PERIPHERAL (18 patients)
CARDIAC DISORDER (18 patients)
PYREXIA (17 patients)
PNEUMONIA (17 patients)
WEIGHT INCREASED (16 patients)
DRUG INTERACTION (16 patients)
CONSTIPATION (16 patients)
INSOMNIA (16 patients)
ABDOMINAL DISTENSION (15 patients)
WEIGHT DECREASED (15 patients)
DRUG HYPERSENSITIVITY (15 patients)
CEREBROVASCULAR ACCIDENT (15 patients)
ANAEMIA (14 patients)
HEADACHE (14 patients)
DEATH (14 patients)
INTERVERTEBRAL DISC PROTRUSION (14 patients)
SWELLING (13 patients)
PULMONARY HYPERTENSION (13 patients)
HYPERLIPIDAEMIA (13 patients)
BLOOD GLUCOSE INCREASED (13 patients)
INFECTION (13 patients)
FLUID RETENTION (13 patients)
FACIAL PAIN (13 patients)
CARPAL TUNNEL SYNDROME (13 patients)
CATARACT (13 patients)
VISION BLURRED (13 patients)
URINARY TRACT INFECTION (13 patients)
MUSCULOSKELETAL PAIN (13 patients)
ACTIVITIES OF DAILY LIVING IMPAIRED (12 patients)
HYPOAESTHESIA (12 patients)
ATRIAL FIBRILLATION (12 patients)
DIABETIC RETINOPATHY (12 patients)
TREMOR (12 patients)
CARDIAC ARREST (12 patients)
GASTROINTESTINAL HAEMORRHAGE (12 patients)
LIPOMA (12 patients)
HYPOTENSION (12 patients)
RESPIRATORY FAILURE (11 patients)
OBESITY (11 patients)
HYPOGLYCAEMIA (11 patients)
DEHYDRATION (11 patients)
GINGIVITIS (11 patients)
WHITE BLOOD CELL COUNT INCREASED (11 patients)
BLOOD PRESSURE INCREASED (11 patients)
ROTATOR CUFF SYNDROME (11 patients)
BRADYCARDIA (11 patients)
BUNDLE BRANCH BLOCK LEFT (11 patients)
PANIC ATTACK (11 patients)
MALAISE (11 patients)
CARDIOMEGALY (11 patients)
DIABETES MELLITUS (11 patients)
DECREASED APPETITE (11 patients)
PARTIAL SEIZURES (10 patients)
CONJUNCTIVITIS ALLERGIC (10 patients)
NEUROSIS (10 patients)
ABSCESS LIMB (10 patients)
OROPHARYNGEAL BLISTERING (10 patients)
COMPLEX REGIONAL PAIN SYNDROME (10 patients)
RHEUMATOID ARTHRITIS (10 patients)
ALANINE AMINOTRANSFERASE INCREASED (10 patients)
CONVULSION (10 patients)
LOSS OF CONSCIOUSNESS (10 patients)
ANGIOLIPOMA (10 patients)
TOOTH LOSS (10 patients)
MYALGIA (10 patients)
NEPHROPATHY (10 patients)
HYPOKALAEMIA (10 patients)
OSTEOPOROSIS (10 patients)
ARTHRITIS (10 patients)
RETINAL VASCULAR DISORDER (10 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (10 patients)
SUBCUTANEOUS NODULE (10 patients)
DIABETIC COMA (10 patients)
SYNOVIAL RUPTURE (10 patients)
LUMBAR RADICULOPATHY (10 patients)
PHOTOPSIA (10 patients)
BLINDNESS (10 patients)
MUSCULAR WEAKNESS (10 patients)
VITREOUS HAEMORRHAGE (10 patients)
BLOOD CREATININE INCREASED (10 patients)
PNEUMONIA BACTERIAL (10 patients)
OPTIC NERVE INJURY (10 patients)
SINUS HEADACHE (10 patients)
BLOOD UREA INCREASED (10 patients)
OSTEOARTHRITIS (10 patients)
RETINAL DETACHMENT (10 patients)
BONE SARCOMA (10 patients)
EYE HAEMORRHAGE (10 patients)
BUNDLE BRANCH BLOCK RIGHT (10 patients)
THERMAL BURN (10 patients)
PERIPHERAL VASCULAR DISORDER (10 patients)
HUMERUS FRACTURE (10 patients)
GLUCOSE TOLERANCE DECREASED (10 patients)
DRUG SCREEN FALSE POSITIVE (10 patients)
PNEUMONIA VIRAL (10 patients)
VENTRICULAR FIBRILLATION (10 patients)
ABASIA (9 patients)
ABDOMINAL PAIN (9 patients)
FACE OEDEMA (9 patients)
IMPAIRED HEALING (9 patients)
ORTHOPEDIC PROCEDURE (9 patients)
ORAL PAIN (9 patients)
MITRAL VALVE INCOMPETENCE (9 patients)
PULMONARY EMBOLISM (9 patients)
OEDEMA (9 patients)
BLOOD PRESSURE DECREASED (9 patients)
COUGH (9 patients)
ERYTHEMA (9 patients)
CORONARY ARTERY DISEASE (9 patients)
FEELING ABNORMAL (9 patients)
STAPHYLOCOCCAL INFECTION (8 patients)
VENTRICULAR TACHYCARDIA (8 patients)
SLEEP APNOEA SYNDROME (8 patients)
VERTIGO (8 patients)
LIGAMENT DISORDER (8 patients)
LYMPHADENOPATHY (8 patients)
CONDITION AGGRAVATED (8 patients)
ARRHYTHMIA (8 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (8 patients)
OSTEOMA (8 patients)
FOOT DEFORMITY (8 patients)
PIRIFORMIS SYNDROME (8 patients)
BONE DENSITY DECREASED (8 patients)
OSTEOMYELITIS (8 patients)
FEMUR FRACTURE (8 patients)
FOOT FRACTURE (8 patients)
PERIORBITAL HAEMATOMA (8 patients)
MALIGNANT NEOPLASM PROGRESSION (8 patients)
VITREOUS FLOATERS (8 patients)
DYSPHAGIA (8 patients)
TORSADE DE POINTES (8 patients)
VENTRICULAR EXTRASYSTOLES (8 patients)
PRURITUS (8 patients)
PHARMACEUTICAL PRODUCT COMPLAINT (7 patients)
HAEMATEMESIS (7 patients)
THROMBOSIS (7 patients)
WHEEZING (7 patients)
WOUND (7 patients)
PANCREATITIS (7 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (7 patients)
NEOPLASM MALIGNANT (7 patients)
COMPRESSION FRACTURE (7 patients)
PAIN IN JAW (7 patients)
PANCYTOPENIA (7 patients)
RADICULAR PAIN (7 patients)
HYPERTENSION (7 patients)
HYPERHIDROSIS (7 patients)
RASH (7 patients)
SOMNOLENCE (7 patients)
GASTRIC ULCER (7 patients)
HYPOPHAGIA (7 patients)
MEDICATION ERROR (7 patients)
HEAD INJURY (7 patients)
HYDRONEPHROSIS (6 patients)
LACTIC ACIDOSIS (6 patients)
ELECTROCARDIOGRAM QT PROLONGED (6 patients)
LOOSE BODY IN JOINT (6 patients)
ANGINA PECTORIS (6 patients)
METATARSALGIA (6 patients)
PLATELET COUNT INCREASED (6 patients)
SINUS BRADYCARDIA (6 patients)
ASCITES (6 patients)
LETHARGY (6 patients)
PANCREATITIS ACUTE (6 patients)
TUBERCULIN TEST POSITIVE (6 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (6 patients)
NECK PAIN (6 patients)
NASOPHARYNGITIS (6 patients)
OSTEONECROSIS OF JAW (6 patients)
BONE DISORDER (6 patients)
SURGERY (6 patients)
EOSINOPHILIA (6 patients)
GAIT DISTURBANCE (6 patients)
SINUSITIS (6 patients)
SKIN ULCER (6 patients)
PERICARDIAL EFFUSION (6 patients)
GINGIVAL BLEEDING (6 patients)
PHARYNGOLARYNGEAL PAIN (6 patients)
ORTHOSTATIC HYPOTENSION (6 patients)
MENTAL STATUS CHANGES (6 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (6 patients)
TUBERCULOSIS (6 patients)
PRIMARY SEQUESTRUM (6 patients)
MUSCLE SPASMS (6 patients)

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Recent FactMed Activity for ALDACTAZIDE


Issue Description / Topic Timestamp
QUESTION
ERECTILE DYSFUNCTION
ı have had hipertension for 12 years.now 42 years old.ı used various anti hipertansif pills and now ı have renal kidnetinsufficiency. ı have been using beta blocker(beloc zok),adalat,cardura for 2 months.and now ı m adviced to use aldaktazide once a day.ı have felt erectile disfunction for 2 t months.will aldaktazide help me for erectile disfunction.what can ı do to cope with this problem 2017-02-13 13:51:16

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