Study of possible correlation between TINNITUS and ALDACTAZIDE

Accompanying discussion about FactMed users Questions and Concerns

 

About this FactMed analysis covering adverse side effect reports of ALDACTAZIDE patients who developed TINNITUS.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 2 individuals taking ALDACTAZIDE reported TINNITUS to the FDA. A total of 517 ALDACTAZIDE drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between ALDACTAZIDE and TINNITUS. In doing so, we compare ALDACTAZIDE with other drugs that cause TINNITUS, to help you evaluate whether or not ALDACTAZIDE causes TINNITUS. Likewise, this page shows the most highly-reported side effects of ALDACTAZIDE, so you can see if TINNITUS ranks among ALDACTAZIDE's most well-known side effects.
Summary Statistics
Reports of ALDACTAZIDE causing TINNITUS: 2
Reports of any side effect of ALDACTAZIDE : 517
Percentage of ALDACTAZIDE patients where TINNITUS is a reported side effect: 0.3868%

FDA reports of any drug causing TINNITUS : 13210
Average percentage for all medicated patients where TINNITUS is reported as a complication: 0.0828%

Physician opinion on ALDACTAZIDE as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing ALDACTAZIDE:
HYPERTENSION ( 73 patients )
DRUG USE FOR UNKNOWN INDICATION ( 18 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 11 patients )
ILL-DEFINED DISORDER ( 8 patients )
OEDEMA PERIPHERAL ( 7 patients )
BLOOD PRESSURE ( 6 patients )
ESSENTIAL HYPERTENSION ( 5 patients )
CARDIAC DISORDER ( 4 patients )
DIURETIC THERAPY ( 4 patients )
OEDEMA ( 3 patients )
SWELLING ( 3 patients )
FLUID RETENTION ( 2 patients )
CARDIAC FAILURE CHRONIC ( 2 patients )
RHEUMATOID ARTHRITIS ( 1 patients )
BLOOD PRESSURE FLUCTUATION ( 1 patients )
TYPE 2 DIABETES MELLITUS ( 1 patients )
CARDIAC FAILURE ( 1 patients )
DIURETIC EFFECT ( 1 patients )
HYPERTENSIVE CARDIOMYOPATHY ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with TINNITUS:

FOSAMAX (1815 patients)
ASPIRIN (1069 patients)
VIOXX (1035 patients)
PAXIL (555 patients)
CYMBALTA (553 patients)
LIPITOR (547 patients)
SYNTHROID (496 patients)
EFFEXOR XR (488 patients)
NEXIUM (409 patients)
XANAX (394 patients)
LYRICA (386 patients)
CELEBREX (368 patients)
ZOMETA (361 patients)
HYDROCHLOROTHIAZIDE (355 patients)
ATENOLOL (346 patients)
WELLBUTRIN XL (338 patients)
NEURONTIN (336 patients)
ZOLOFT (331 patients)
LISINOPRIL (330 patients)
ENBREL (329 patients)
HUMIRA (328 patients)
LEVAQUIN (327 patients)
SEROQUEL (327 patients)
AMBIEN (304 patients)
TOPROL-XL (303 patients)
PREDNISONE (294 patients)
LEXAPRO (291 patients)
OMEPRAZOLE (287 patients)
WELLBUTRIN (278 patients)
FOLIC ACID (274 patients)
CLONAZEPAM (269 patients)
PRILOSEC (268 patients)
SIMVASTATIN (266 patients)
ZOCOR (261 patients)
LORAZEPAM (251 patients)
CHANTIX (245 patients)
PREVACID (243 patients)
IBUPROFEN (239 patients)
PREMARIN (238 patients)
CRESTOR (237 patients)
EFFEXOR (236 patients)
NORVASC (234 patients)
OXYCONTIN (232 patients)
COUMADIN (228 patients)
METHOTREXATE (222 patients)
LEVOTHYROXINE SODIUM (220 patients)
PROTONIX (217 patients)
DIOVAN (217 patients)
ALENDRONATE SODIUM (216 patients)
PEGASYS (210 patients)
PAROXETINE HCL (208 patients)
PRISTIQ (207 patients)
AREDIA (205 patients)
LASIX (203 patients)
ALBUTEROL (201 patients)
ATIVAN (194 patients)
KLONOPIN (192 patients)
DIAZEPAM (191 patients)
CIPROFLOXACIN (190 patients)
VITAMIN D (185 patients)
VALIUM (176 patients)
PLAVIX (176 patients)
PROZAC (175 patients)
FOSAMAX PLUS D (175 patients)
ZITHROMAX (170 patients)
ACETAMINOPHEN (169 patients)
FORTEO (169 patients)
VICODIN (168 patients)
SINGULAIR (168 patients)
AMOXICILLIN (164 patients)
FUROSEMIDE (158 patients)
TOPAMAX (156 patients)
TEGRETOL (150 patients)
VITAMIN E (148 patients)
VIAGRA (148 patients)
LAMICTAL (147 patients)
CELEXA (146 patients)
CALCIUM (145 patients)
GABAPENTIN (144 patients)
ALPRAZOLAM (144 patients)
NIASPAN (141 patients)
METFORMIN HCL (141 patients)
ADVAIR DISKUS 100/50 (141 patients)
REMICADE (141 patients)
LORTAB (140 patients)
AVONEX (140 patients)
COZAAR (140 patients)
DURAGESIC-100 (139 patients)
DEXAMETHASONE (138 patients)
ALLOPURINOL (136 patients)
TYSABRI (136 patients)
ZANTAC (135 patients)
AVELOX (135 patients)
ALLEGRA (134 patients)
COPEGUS (133 patients)
CIPRO (130 patients)
DIGOXIN (129 patients)
BONIVA (128 patients)
FLEXERIL (128 patients)
MORPHINE (125 patients)
[THERAPY UNSPECIFIED] (124 patients)
ACCUTANE (123 patients)
ACTONEL (123 patients)
CLARITIN (122 patients)
POTASSIUM CHLORIDE (121 patients)
XALATAN (121 patients)
METOPROLOL TARTRATE (121 patients)
VITAMINS (UNSPECIFIED) (121 patients)
DEPAKOTE (119 patients)
TRAZODONE HCL (119 patients)
ZOFRAN (119 patients)
LARIAM (118 patients)
AMLODIPINE (117 patients)
TRAMADOL HCL (116 patients)
ASCORBIC ACID (115 patients)
WARFARIN SODIUM (113 patients)
FLOMAX (111 patients)
LEVOXYL (111 patients)
PERCOCET (110 patients)
MULTI-VITAMIN (108 patients)
RIBAVIRIN (108 patients)
BENADRYL (107 patients)
OXYCODONE HCL (106 patients)
ZYRTEC (104 patients)
PREDNISOLONE (103 patients)
PREDNISONE TAB (103 patients)
CALCIUM (UNSPECIFIED) (102 patients)
ELAVIL (101 patients)
ZETIA (101 patients)
CIALIS (100 patients)
AMITRIPTYLINE HCL (100 patients)
PAXIL CR (99 patients)
METOPROLOL (97 patients)
RANITIDINE (96 patients)
COREG (96 patients)
REGLAN (96 patients)
FISH OIL (95 patients)
EXJADE (95 patients)
LANSOPRAZOLE (95 patients)
AVANDIA (93 patients)
LANTUS (93 patients)
PROMETHAZINE (92 patients)
HYDROCODONE BITARTRATE (92 patients)
GLUCOPHAGE (92 patients)
NAPROXEN (92 patients)
FLONASE (92 patients)
CISPLATIN (92 patients)
VALTREX (91 patients)
ALTACE (91 patients)
SOMA (90 patients)
TYLENOL (CAPLET) (90 patients)
AZITHROMYCIN (90 patients)
WELLBUTRIN SR (89 patients)
COMPAZINE (89 patients)
MULTI-VITAMINS (89 patients)
TYLENOL (88 patients)
REVLIMID (87 patients)
RISPERDAL (87 patients)
MIRTAZAPINE (86 patients)
ACIPHEX (86 patients)
NITROGLYCERIN (84 patients)
DOXYCYCLINE (84 patients)
VITAMIN B-12 (84 patients)
NO CONCURRENT MEDICATION (83 patients)
HYDROCODONE (81 patients)
LOPRESSOR (81 patients)
PRAVACHOL (80 patients)
ARIMIDEX (80 patients)
LUNESTA (79 patients)
COLACE (79 patients)
PROPRANOLOL (79 patients)
THALIDOMIDE (79 patients)
NASONEX (79 patients)
CEPHALEXIN (78 patients)
MECLIZINE (77 patients)
LEVITRA (76 patients)
BACLOFEN (76 patients)
MOBIC (76 patients)
CLINDAMYCIN (75 patients)
METOPROLOL SUCCINATE (75 patients)
GLYBURIDE (75 patients)
TEMAZEPAM (75 patients)
MOTRIN (74 patients)
LEVOTHROID (74 patients)
PEG-INTRON (74 patients)
TAXOTERE (74 patients)
SPIRIVA (74 patients)
BUSPAR (72 patients)
REBIF (72 patients)
NAMENDA (72 patients)
DECADRON (71 patients)
VITAMINS (71 patients)
MELOXICAM (71 patients)
VYTORIN (71 patients)
BYETTA (71 patients)
CITALOPRAM HYDROBROMIDE (70 patients)
BEXTRA (70 patients)
ACYCLOVIR (70 patients)
ENALAPRIL MALEATE (69 patients)
IRON (69 patients)
IMITREX (69 patients)
RADIATION THERAPY (68 patients)
ULTRAM (68 patients)
NASACORT (68 patients)
ACTOS (68 patients)
ALEVE (68 patients)
KEPPRA (68 patients)
SPIRONOLACTONE (67 patients)
METFORMIN (67 patients)
BUPROPION HCL (67 patients)
Most common side effects for patients taking ALDACTAZIDE:
FALL (42 patients)
DYSPNOEA (38 patients)
OEDEMA PERIPHERAL (36 patients)
RENAL FAILURE (36 patients)
ASTHENIA (34 patients)
RENAL FAILURE ACUTE (32 patients)
CHEST PAIN (30 patients)
PAIN IN EXTREMITY (29 patients)
CONFUSIONAL STATE (28 patients)
PAIN (28 patients)
DIARRHOEA (27 patients)
DIZZINESS (27 patients)
BACK PAIN (26 patients)
NAUSEA (26 patients)
MYOCARDIAL INFARCTION (25 patients)
DRUG INEFFECTIVE (25 patients)
HYPONATRAEMIA (25 patients)
CARDIAC FAILURE (25 patients)
FATIGUE (22 patients)
ANXIETY (22 patients)
VOMITING (22 patients)
CARDIAC FAILURE CONGESTIVE (22 patients)
DEPRESSION (21 patients)
ARTHRALGIA (20 patients)
CELLULITIS (19 patients)
HYPERKALAEMIA (18 patients)
NEUROPATHY PERIPHERAL (18 patients)
CARDIAC DISORDER (18 patients)
PYREXIA (17 patients)
PNEUMONIA (17 patients)
WEIGHT INCREASED (16 patients)
DRUG INTERACTION (16 patients)
CONSTIPATION (16 patients)
INSOMNIA (16 patients)
ABDOMINAL DISTENSION (15 patients)
WEIGHT DECREASED (15 patients)
DRUG HYPERSENSITIVITY (15 patients)
CEREBROVASCULAR ACCIDENT (15 patients)
ANAEMIA (14 patients)
HEADACHE (14 patients)
DEATH (14 patients)
INTERVERTEBRAL DISC PROTRUSION (14 patients)
SWELLING (13 patients)
PULMONARY HYPERTENSION (13 patients)
HYPERLIPIDAEMIA (13 patients)
BLOOD GLUCOSE INCREASED (13 patients)
INFECTION (13 patients)
FLUID RETENTION (13 patients)
FACIAL PAIN (13 patients)
CARPAL TUNNEL SYNDROME (13 patients)
CATARACT (13 patients)
VISION BLURRED (13 patients)
URINARY TRACT INFECTION (13 patients)
MUSCULOSKELETAL PAIN (13 patients)
ACTIVITIES OF DAILY LIVING IMPAIRED (12 patients)
HYPOAESTHESIA (12 patients)
ATRIAL FIBRILLATION (12 patients)
DIABETIC RETINOPATHY (12 patients)
TREMOR (12 patients)
CARDIAC ARREST (12 patients)
GASTROINTESTINAL HAEMORRHAGE (12 patients)
LIPOMA (12 patients)
HYPOTENSION (12 patients)
RESPIRATORY FAILURE (11 patients)
OBESITY (11 patients)
HYPOGLYCAEMIA (11 patients)
DEHYDRATION (11 patients)
GINGIVITIS (11 patients)
WHITE BLOOD CELL COUNT INCREASED (11 patients)
BLOOD PRESSURE INCREASED (11 patients)
ROTATOR CUFF SYNDROME (11 patients)
BRADYCARDIA (11 patients)
BUNDLE BRANCH BLOCK LEFT (11 patients)
PANIC ATTACK (11 patients)
MALAISE (11 patients)
CARDIOMEGALY (11 patients)
DIABETES MELLITUS (11 patients)
DECREASED APPETITE (11 patients)
PARTIAL SEIZURES (10 patients)
CONJUNCTIVITIS ALLERGIC (10 patients)
NEUROSIS (10 patients)
ABSCESS LIMB (10 patients)
OROPHARYNGEAL BLISTERING (10 patients)
COMPLEX REGIONAL PAIN SYNDROME (10 patients)
RHEUMATOID ARTHRITIS (10 patients)
ALANINE AMINOTRANSFERASE INCREASED (10 patients)
CONVULSION (10 patients)
LOSS OF CONSCIOUSNESS (10 patients)
ANGIOLIPOMA (10 patients)
TOOTH LOSS (10 patients)
MYALGIA (10 patients)
NEPHROPATHY (10 patients)
HYPOKALAEMIA (10 patients)
OSTEOPOROSIS (10 patients)
ARTHRITIS (10 patients)
RETINAL VASCULAR DISORDER (10 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (10 patients)
SUBCUTANEOUS NODULE (10 patients)
DIABETIC COMA (10 patients)
SYNOVIAL RUPTURE (10 patients)
LUMBAR RADICULOPATHY (10 patients)
PHOTOPSIA (10 patients)
BLINDNESS (10 patients)
MUSCULAR WEAKNESS (10 patients)
VITREOUS HAEMORRHAGE (10 patients)
BLOOD CREATININE INCREASED (10 patients)
PNEUMONIA BACTERIAL (10 patients)
OPTIC NERVE INJURY (10 patients)
SINUS HEADACHE (10 patients)
BLOOD UREA INCREASED (10 patients)
OSTEOARTHRITIS (10 patients)
RETINAL DETACHMENT (10 patients)
BONE SARCOMA (10 patients)
EYE HAEMORRHAGE (10 patients)
BUNDLE BRANCH BLOCK RIGHT (10 patients)
THERMAL BURN (10 patients)
PERIPHERAL VASCULAR DISORDER (10 patients)
HUMERUS FRACTURE (10 patients)
GLUCOSE TOLERANCE DECREASED (10 patients)
DRUG SCREEN FALSE POSITIVE (10 patients)
PNEUMONIA VIRAL (10 patients)
VENTRICULAR FIBRILLATION (10 patients)
ABASIA (9 patients)
ABDOMINAL PAIN (9 patients)
FACE OEDEMA (9 patients)
IMPAIRED HEALING (9 patients)
ORTHOPEDIC PROCEDURE (9 patients)
ORAL PAIN (9 patients)
MITRAL VALVE INCOMPETENCE (9 patients)
PULMONARY EMBOLISM (9 patients)
OEDEMA (9 patients)
BLOOD PRESSURE DECREASED (9 patients)
COUGH (9 patients)
ERYTHEMA (9 patients)
CORONARY ARTERY DISEASE (9 patients)
FEELING ABNORMAL (9 patients)
STAPHYLOCOCCAL INFECTION (8 patients)
VENTRICULAR TACHYCARDIA (8 patients)
SLEEP APNOEA SYNDROME (8 patients)
VERTIGO (8 patients)
LIGAMENT DISORDER (8 patients)
LYMPHADENOPATHY (8 patients)
CONDITION AGGRAVATED (8 patients)
ARRHYTHMIA (8 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (8 patients)
OSTEOMA (8 patients)
FOOT DEFORMITY (8 patients)
PIRIFORMIS SYNDROME (8 patients)
BONE DENSITY DECREASED (8 patients)
OSTEOMYELITIS (8 patients)
FEMUR FRACTURE (8 patients)
FOOT FRACTURE (8 patients)
PERIORBITAL HAEMATOMA (8 patients)
MALIGNANT NEOPLASM PROGRESSION (8 patients)
VITREOUS FLOATERS (8 patients)
DYSPHAGIA (8 patients)
TORSADE DE POINTES (8 patients)
VENTRICULAR EXTRASYSTOLES (8 patients)
PRURITUS (8 patients)
PHARMACEUTICAL PRODUCT COMPLAINT (7 patients)
HAEMATEMESIS (7 patients)
THROMBOSIS (7 patients)
WHEEZING (7 patients)
WOUND (7 patients)
PANCREATITIS (7 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (7 patients)
NEOPLASM MALIGNANT (7 patients)
COMPRESSION FRACTURE (7 patients)
PAIN IN JAW (7 patients)
PANCYTOPENIA (7 patients)
RADICULAR PAIN (7 patients)
HYPERTENSION (7 patients)
HYPERHIDROSIS (7 patients)
RASH (7 patients)
SOMNOLENCE (7 patients)
GASTRIC ULCER (7 patients)
HYPOPHAGIA (7 patients)
MEDICATION ERROR (7 patients)
HEAD INJURY (7 patients)
HYDRONEPHROSIS (6 patients)
LACTIC ACIDOSIS (6 patients)
ELECTROCARDIOGRAM QT PROLONGED (6 patients)
LOOSE BODY IN JOINT (6 patients)
ANGINA PECTORIS (6 patients)
METATARSALGIA (6 patients)
PLATELET COUNT INCREASED (6 patients)
SINUS BRADYCARDIA (6 patients)
ASCITES (6 patients)
LETHARGY (6 patients)
PANCREATITIS ACUTE (6 patients)
TUBERCULIN TEST POSITIVE (6 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (6 patients)
NECK PAIN (6 patients)
NASOPHARYNGITIS (6 patients)
OSTEONECROSIS OF JAW (6 patients)
BONE DISORDER (6 patients)
SURGERY (6 patients)
EOSINOPHILIA (6 patients)
GAIT DISTURBANCE (6 patients)
SINUSITIS (6 patients)
SKIN ULCER (6 patients)
PERICARDIAL EFFUSION (6 patients)
GINGIVAL BLEEDING (6 patients)
PHARYNGOLARYNGEAL PAIN (6 patients)
ORTHOSTATIC HYPOTENSION (6 patients)
MENTAL STATUS CHANGES (6 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (6 patients)
TUBERCULOSIS (6 patients)
PRIMARY SEQUESTRUM (6 patients)
MUSCLE SPASMS (6 patients)

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Recent FactMed Activity for ALDACTAZIDE

Issue Description / Topic Timestamp
QUESTION
ERECTILE DYSFUNCTION		 ı have had hipertension for 12 years.now 42 years old.ı used various anti hipertansif pills and now ı have renal kidnetinsufficiency. ı have been using beta blocker(beloc zok),adalat,cardura for 2 months.and now ı m adviced to use aldaktazide once a day.ı have felt erectile disfunction for 2 t months.will aldaktazide help me for erectile disfunction.what can ı do to cope with this problem 2017-02-13 13:51:16

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