About this FactMed analysis covering adverse side effect reports of ALFENTANIL patients who developed AKATHISIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 8 individuals taking ALFENTANIL reported AKATHISIA to the FDA. A total of 427 ALFENTANIL drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between ALFENTANIL and AKATHISIA. In doing so, we compare ALFENTANIL with other drugs that cause AKATHISIA, to help you evaluate whether or not ALFENTANIL causes AKATHISIA. Likewise, this page shows the most highly-reported side effects of ALFENTANIL, so you can see if AKATHISIA ranks among ALFENTANIL's most well-known side effects.
Summary Statistics
Reports of ALFENTANIL causing AKATHISIA: 8
Reports of any side effect of ALFENTANIL : 427
Percentage of ALFENTANIL patients where AKATHISIA is a reported side effect: 1.8735%

FDA reports of any drug causing AKATHISIA : 4768
Average percentage for all medicated patients where AKATHISIA is reported as a complication: 0.0299%

Physician opinion on ALFENTANIL as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing ALFENTANIL:
ANAESTHESIA ( 63 patients )
GENERAL ANAESTHESIA ( 52 patients )
SEDATION ( 17 patients )
DRUG USE FOR UNKNOWN INDICATION ( 16 patients )
INDUCTION OF ANAESTHESIA ( 16 patients )
OSTEOTOMY ( 15 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 13 patients )
PAIN ( 6 patients )
SENSORY DISTURBANCE ( 5 patients )
DRUG ABUSE ( 4 patients )
ANAESTHESIA PROCEDURE ( 3 patients )
IN VITRO FERTILISATION ( 3 patients )
DRUG WITHDRAWAL SYNDROME ( 2 patients )
ILL-DEFINED DISORDER ( 2 patients )
MUSCLE RELAXANT THERAPY ( 1 patients )
PNEUMONIA ( 1 patients )
DISCOMFORT ( 1 patients )
SURGERY ( 1 patients )
LIGHT ANAESTHESIA ( 1 patients )
PERIOPERATIVE ANALGESIA ( 1 patients )
POST PROCEDURAL PAIN ( 1 patients )
COLONOSCOPY ( 1 patients )
RETINAL DETACHMENT ( 1 patients )
VARICOSE VEIN OPERATION ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with AKATHISIA:

METOCLOPRAMIDE (2134 patients)
ABILIFY (619 patients)
REGLAN (552 patients)
RISPERDAL (475 patients)
ZYPREXA (370 patients)
SEROQUEL (354 patients)
PAXIL (224 patients)
GEODON (187 patients)
LORAZEPAM (177 patients)
METOCLOPRAMIDE HYDROCHLORIDE (173 patients)
RISPERIDONE (152 patients)
OLANZAPINE (146 patients)
HALOPERIDOL (141 patients)
CYMBALTA (139 patients)
ZOLOFT (138 patients)
DIAZEPAM (134 patients)
LEXAPRO (130 patients)
INVEGA (123 patients)
SAPHRIS (114 patients)
MIRTAZAPINE (106 patients)
CITALOPRAM HYDROBROMIDE (106 patients)
EFFEXOR XR (106 patients)
FLUOXETINE (103 patients)
RISPERDAL CONSTA (103 patients)
INVEGA SUSTENNA (99 patients)
PAROXETINE HCL (99 patients)
DEPAKOTE (97 patients)
KLONOPIN (95 patients)
EFFEXOR (84 patients)
CLONAZEPAM (83 patients)
HALDOL (83 patients)
ASPIRIN (83 patients)
XANAX (82 patients)
TRAZODONE HCL (79 patients)
CLOZAPINE (79 patients)
PALIPERIDONE (76 patients)
AMBIEN (76 patients)
LITHIUM CARBONATE (70 patients)
VALPROATE SODIUM (69 patients)
ATIVAN (67 patients)
LAMICTAL (63 patients)
PROZAC (61 patients)
ARIPIPRAZOLE (61 patients)
SIMVASTATIN (55 patients)
SERTRALINE HYDROCHLORIDE (53 patients)
VENLAFAXINE (51 patients)
NEXIUM (51 patients)
OMEPRAZOLE (51 patients)
OXYCODONE HCL (48 patients)
ZOLPIDEM (48 patients)
PROTONIX (47 patients)
AKINETON (46 patients)
GABAPENTIN (45 patients)
WELLBUTRIN (44 patients)
ATENOLOL (43 patients)
PROPRANOLOL (43 patients)
LIPITOR (43 patients)
PAXIL CR (42 patients)
LISINOPRIL (42 patients)
FLUOXETINE HCL (41 patients)
ATORVASTATIN (40 patients)
PROMETHAZINE (40 patients)
NEURONTIN (39 patients)
LEVOTHYROXINE SODIUM (38 patients)
ZOLPIDEM TARTRATE (38 patients)
AMITRIPTYLINE HCL (38 patients)
ALCOHOL (37 patients)
PRISTIQ (37 patients)
TRAMADOL HCL (37 patients)
VALIUM (36 patients)
CLOZARIL (36 patients)
CELEXA (36 patients)
ALPRAZOLAM (36 patients)
LITHIUM (36 patients)
VENLAFAXINE HCL (36 patients)
SYNTHROID (35 patients)
CLONIDINE (35 patients)
BENADRYL (35 patients)
CEPHALEXIN (34 patients)
REMERON (34 patients)
MORPHINE (34 patients)
ERYTHROMYCIN (34 patients)
QUETIAPINE (33 patients)
SEROQUEL XR (33 patients)
ESCITALOPRAM (32 patients)
IBUPROFEN (32 patients)
DURAGESIC-100 (32 patients)
PREVACID (31 patients)
COGENTIN (31 patients)
TRIHEXYPHENIDYL HCL (31 patients)
MAGNESIUM OXIDE (31 patients)
ZOPICLONE (31 patients)
OXYCONTIN (30 patients)
PROPOFOL (30 patients)
QUETIAPINE FUMARATE (30 patients)
VICODIN (29 patients)
CIPROFLOXACIN (29 patients)
ALBUTEROL (29 patients)
BENDROFLUMETHIAZIDE (29 patients)
IRBESARTAN (28 patients)
RANITIDINE (28 patients)
FUROSEMIDE (28 patients)
VIOXX (28 patients)
PREV MEDS (28 patients)
SERTRALINE (28 patients)
PREMARIN (27 patients)
PRILOSEC (27 patients)
CON MEDS (27 patients)
RAMIPRIL (27 patients)
LAMOTRIGINE (27 patients)
ACETAMINOPHEN (26 patients)
LOVASTATIN (26 patients)
CITALOPRAM (26 patients)
BIPERIDEN HYDROCHLORIDE (26 patients)
ESCITALOPRAM OXALATE (24 patients)
CARBAMAZEPINE (24 patients)
CELEBREX (24 patients)
LYRICA (24 patients)
HYDROCHLOROTHIAZIDE (24 patients)
PAROXETINE HYDROCHLORIDE (24 patients)
TOPAMAX (23 patients)
METOCLOPRAMIDE HCL (23 patients)
AMOXICILLIN (23 patients)
TEGRETOL (23 patients)
PAROXETINE (23 patients)
FLEXERIL (22 patients)
TRILEPTAL (22 patients)
FELODIPINE (22 patients)
CONCERTA (22 patients)
VIMPAT (22 patients)
HYDROCODONE BITARTRATE AND ACETAMINOPHEN (21 patients)
VALPROIC ACID (21 patients)
TEMAZEPAM (21 patients)
ALLEGRA (21 patients)
ZELDOX (21 patients)
HALOPERIDOL DECANOATE (21 patients)
MELPERON (20 patients)
ROHYPNOL (20 patients)
DUODOPA GEL (20 patients)
ISOSORBIDE MONONITRATE (20 patients)
TENORMIN (20 patients)
METFORMIN HCL (20 patients)
REQUIP (19 patients)
STRATTERA (19 patients)
DIPHENHYDRAMINE HCL (19 patients)
BENZTROPINE MESYLATE (19 patients)
LANSOPRAZOLE (19 patients)
QUAZEPAM (19 patients)
BIPERIDEN HYDROCHLORIDE TAB (19 patients)
FLUVOXAMINE MALEATE (19 patients)
PRAVASTATIN (19 patients)
NITRAZEPAM (18 patients)
FLUPHENAZINE (18 patients)
SINGULAIR (18 patients)
SINEMET (18 patients)
NORVASC (17 patients)
LUNESTA (17 patients)
PROCHLORPERAZINE (17 patients)
ZELDOX (CAPSULES) (17 patients)
CELECOXIB (17 patients)
SERZONE (17 patients)
AMLODIPINE (17 patients)
COLACE (17 patients)
FLUNITRAZEPAM (16 patients)
LASIX (16 patients)
BROTIZOLAM (16 patients)
TETRABENAZINE (16 patients)
PLAVIX (16 patients)
RITALIN (16 patients)
CLORAZEPATE DIPOTASSIUM (16 patients)
KEPPRA (16 patients)
SENNOSIDE (16 patients)
ROCURONIUM BROMIDE (16 patients)
CYCLOBENZAPRINE (16 patients)
FENOFIBRATE (16 patients)
PERCOCET (15 patients)
BECONASE (15 patients)
FLUTICASONE PROPIONATE/SALMETEROL (15 patients)
METHOTREXATE (15 patients)
DOXYCYCLINE (14 patients)
CRESTOR (14 patients)
LEVOMEPROMAZINE (14 patients)
LORTAB (14 patients)
VENLAFAXINE HYDROCHLORIDE (14 patients)
ADVAIR DISKUS 100/50 (14 patients)
AZITHROMYCIN (14 patients)
NASONEX (14 patients)
ETIZOLAM (14 patients)
PREDNISONE (14 patients)
ACRIVASTINE (13 patients)
METHYLENE BLUE (13 patients)
WELLBUTRIN XL (13 patients)
BUPROPION HCL (13 patients)
PEPCID (13 patients)
METOPROLOL TARTRATE (13 patients)
GLYBURIDE (13 patients)
MIRAPEX (13 patients)
LUVOX (13 patients)
NAPROXEN (13 patients)
CLARITHROMYCIN (13 patients)
OXAZEPAM (13 patients)
VITAMIN D (13 patients)
CYCLIZINE (13 patients)
ARICEPT (13 patients)
FOLIC ACID (13 patients)
ZYPADHERA (13 patients)
METHYLPHENIDATE (12 patients)
TRAZODONE (12 patients)
DEXAMETHASONE (12 patients)
POTASSIUM (12 patients)
Most common side effects for patients taking ALFENTANIL:
DRUG INTERACTION (75 patients)
DYSTONIA (56 patients)
MYOTONIA (54 patients)
RENAL IMPAIRMENT (42 patients)
SINUS TACHYCARDIA (34 patients)
AGITATION (32 patients)
BACK PAIN (28 patients)
TOXIC EPIDERMAL NECROLYSIS (28 patients)
INFECTION (26 patients)
CARDIAC ARREST (26 patients)
DRUG WITHDRAWAL SYNDROME (26 patients)
THERAPEUTIC AGENT TOXICITY (24 patients)
DRUG EFFECT DECREASED (24 patients)
BRADYCARDIA (23 patients)
TACHYCARDIA (19 patients)
MYOCLONUS (19 patients)
STARING (19 patients)
ANAPHYLACTIC SHOCK (18 patients)
HYPOTENSION (18 patients)
DRUG TOXICITY (18 patients)
MULTI-ORGAN FAILURE (17 patients)
VENTRICULAR FIBRILLATION (16 patients)
BRONCHOSPASM (16 patients)
DEATH (16 patients)
ALANINE AMINOTRANSFERASE INCREASED (15 patients)
OXYGEN SATURATION DECREASED (15 patients)
DRUG EXPOSURE DURING PREGNANCY (15 patients)
HEPATITIS (15 patients)
RESTLESSNESS (14 patients)
PANIC REACTION (14 patients)
LIVER FUNCTION TEST ABNORMAL (14 patients)
ABDOMINAL PAIN (13 patients)
WHITE BLOOD CELL COUNT INCREASED (13 patients)
TUBULOINTERSTITIAL NEPHRITIS (13 patients)
DRUG INEFFECTIVE (13 patients)
DRUG RASH WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS (13 patients)
ANAPHYLACTIC REACTION (12 patients)
HYPERHIDROSIS (12 patients)
NAUSEA (12 patients)
RENAL FAILURE ACUTE (12 patients)
GASTROINTESTINAL HAEMORRHAGE (12 patients)
OEDEMA PERIPHERAL (12 patients)
AGGRESSION (11 patients)
COMA (11 patients)
CYANOSIS (11 patients)
ESCHERICHIA INFECTION (11 patients)
SOMNOLENCE (11 patients)
HAEMOGLOBIN DECREASED (11 patients)
PLEURAL EFFUSION (10 patients)
BLOOD PHOSPHORUS INCREASED (10 patients)
HYPERVENTILATION (10 patients)
CONDITION AGGRAVATED (10 patients)
DISEASE PROGRESSION (10 patients)
HYPOXIA (10 patients)
FEELING ABNORMAL (10 patients)
PULMONARY OEDEMA (9 patients)
SPEECH DISORDER (9 patients)
MYALGIA (9 patients)
ATRIAL FIBRILLATION (9 patients)
PILOERECTION (9 patients)
CAESAREAN SECTION (9 patients)
SEROTONIN SYNDROME (9 patients)
CATATONIA (9 patients)
POST PROCEDURAL COMPLICATION (9 patients)
DYSPNOEA (9 patients)
MYDRIASIS (9 patients)
HEPATIC FAILURE (9 patients)
ACUTE RESPIRATORY DISTRESS SYNDROME (8 patients)
AKATHISIA (8 patients)
ANAESTHETIC COMPLICATION (8 patients)
LACERATION (8 patients)
BLOOD ALBUMIN DECREASED (8 patients)
BLOOD BILIRUBIN INCREASED (8 patients)
BLOOD CALCIUM INCREASED (8 patients)
BRAIN OEDEMA (8 patients)
PNEUMONIA (8 patients)
PUPILLARY REFLEX IMPAIRED (8 patients)
ELECTROCARDIOGRAM QT PROLONGED (8 patients)
RHABDOMYOLYSIS (8 patients)
BLISTER (7 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (7 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (7 patients)
HYPERSENSITIVITY (7 patients)
PYREXIA (7 patients)
C-REACTIVE PROTEIN INCREASED (7 patients)
PARAESTHESIA (7 patients)
VOMITING (7 patients)
PREMATURE RUPTURE OF MEMBRANES (7 patients)
SCLERODERMA (7 patients)
RENAL FAILURE (7 patients)
EXTENSOR PLANTAR RESPONSE (7 patients)
FATIGUE (7 patients)
HAEMATEMESIS (7 patients)
SLEEP DISORDER (7 patients)
PREMATURE LABOUR (7 patients)
ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED (6 patients)
AMNESIA (6 patients)
PEMPHIGOID (6 patients)
PROCEDURAL COMPLICATION (6 patients)
ASCITES INFECTION (6 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (6 patients)
HYPOCOAGULABLE STATE (6 patients)
BLOOD PRESSURE DECREASED (6 patients)
IDIOPATHIC THROMBOCYTOPENIC PURPURA (6 patients)
VENTRICULAR TACHYCARDIA (6 patients)
HYPERGLYCAEMIA (6 patients)
WOUND SECRETION (6 patients)
ENTEROCOCCAL INFECTION (6 patients)
MOVEMENT DISORDER (6 patients)
SEPSIS (6 patients)
NO THERAPEUTIC RESPONSE (6 patients)
GLASGOW COMA SCALE ABNORMAL (6 patients)
ABDOMINAL SEPSIS (5 patients)
HYPOTONIA (5 patients)
HYPERREFLEXIA (5 patients)
APHASIA (5 patients)
ASCITES (5 patients)
HYPERPARATHYROIDISM (5 patients)
HYPOKALAEMIA (5 patients)
CARDIO-RESPIRATORY ARREST (5 patients)
UNRESPONSIVE TO STIMULI (5 patients)
THROMBOCYTOPENIA (5 patients)
PROPOFOL INFUSION SYNDROME (5 patients)
ELECTROCARDIOGRAM ST SEGMENT DEPRESSION (5 patients)
SCREAMING (5 patients)
ISCHAEMIC STROKE (5 patients)
FALL (5 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (5 patients)
TREMOR (5 patients)
HEMIPLEGIA (5 patients)
SMALL INTESTINAL HAEMORRHAGE (5 patients)
NEUTROPENIA (4 patients)
ACCIDENTAL OVERDOSE (4 patients)
RESUSCITATION (4 patients)
AIRWAY COMPLICATION OF ANAESTHESIA (4 patients)
TRANSAMINASES INCREASED (4 patients)
ARRHYTHMIA (4 patients)
ARTHRALGIA (4 patients)
NO ADVERSE EVENT (4 patients)
BLOOD TRIGLYCERIDES INCREASED (4 patients)
INJURY (4 patients)
MATERNAL DRUGS AFFECTING FOETUS (4 patients)
RESPIRATORY DEPRESSION (4 patients)
MOTOR DYSFUNCTION (4 patients)
MUSCLE RIGIDITY (4 patients)
LABILE BLOOD PRESSURE (4 patients)
CELLULITIS (4 patients)
DELAYED RECOVERY FROM ANAESTHESIA (4 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (4 patients)
HYPERTENSION (4 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (4 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (4 patients)
PULMONARY EMBOLISM (4 patients)
ECTOPIC PREGNANCY (4 patients)
RASH ERYTHEMATOUS (4 patients)
MELAENA (4 patients)
FOETAL MALPRESENTATION (4 patients)
NEUTROPHILIA (4 patients)
GRAND MAL CONVULSION (4 patients)
SUBARACHNOID HAEMORRHAGE (4 patients)
OEDEMA (4 patients)
ABORTION INDUCED (3 patients)
ANHEDONIA (3 patients)
VARICOSE VEIN OPERATION (3 patients)
PAIN (3 patients)
ANXIETY (3 patients)
APALLIC SYNDROME (3 patients)
MICROSTOMIA (3 patients)
RESPIRATORY FAILURE (3 patients)
BLOOD CREATININE INCREASED (3 patients)
UNEVALUABLE EVENT (3 patients)
PANIC ATTACK (3 patients)
BLOOD POTASSIUM DECREASED (3 patients)
BONE DISORDER (3 patients)
BRAIN DEATH (3 patients)
CARDIAC DISORDER (3 patients)
METABOLIC ACIDOSIS (3 patients)
SKIN REACTION (3 patients)
PANCREATIC ABSCESS (3 patients)
CEREBRAL HAEMORRHAGE (3 patients)
CEREBRAL ISCHAEMIA (3 patients)
CEREBROVASCULAR ACCIDENT (3 patients)
CHOLESTASIS (3 patients)
ORGAN FAILURE (3 patients)
PANCREATITIS (3 patients)
CONVULSION (3 patients)
CYTOLYTIC HEPATITIS (3 patients)
TUMOUR LYSIS SYNDROME (3 patients)
PANCREATIC NECROSIS (3 patients)
DEHYDRATION (3 patients)
DEPRESSION (3 patients)
PROTHROMBIN TIME PROLONGED (3 patients)
DRUG HYPERSENSITIVITY (3 patients)
HYPOGLYCAEMIA NEONATAL (3 patients)
DYSPHASIA (3 patients)
DYSPHONIA (3 patients)
RENAL INJURY (3 patients)
LOCALISED OEDEMA (3 patients)
ELECTROMECHANICAL DISSOCIATION (3 patients)
RAYNAUD'S PHENOMENON (3 patients)
ERYTHEMA (3 patients)
FACE OEDEMA (3 patients)
FEAR (3 patients)
SEX CHROMOSOME ABNORMALITY (3 patients)
SKIN DISCOLOURATION (3 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (3 patients)
HAEMATOMA (3 patients)
HAEMODIALYSIS (3 patients)
THERAPY NON-RESPONDER (3 patients)
HEART RATE INCREASED (3 patients)

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