About this FactMed analysis covering adverse side effect reports of ALFENTANIL patients who developed ANHEDONIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 3 individuals taking ALFENTANIL reported ANHEDONIA to the FDA. A total of 427 ALFENTANIL drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between ALFENTANIL and ANHEDONIA. In doing so, we compare ALFENTANIL with other drugs that cause ANHEDONIA, to help you evaluate whether or not ALFENTANIL causes ANHEDONIA. Likewise, this page shows the most highly-reported side effects of ALFENTANIL, so you can see if ANHEDONIA ranks among ALFENTANIL's most well-known side effects.
Summary Statistics
Reports of ALFENTANIL causing ANHEDONIA: 3
Reports of any side effect of ALFENTANIL : 427
Percentage of ALFENTANIL patients where ANHEDONIA is a reported side effect: 0.7026%

FDA reports of any drug causing ANHEDONIA : 17054
Average percentage for all medicated patients where ANHEDONIA is reported as a complication: 0.1069%

Physician opinion on ALFENTANIL as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing ALFENTANIL:
ANAESTHESIA ( 63 patients )
GENERAL ANAESTHESIA ( 52 patients )
SEDATION ( 17 patients )
DRUG USE FOR UNKNOWN INDICATION ( 16 patients )
INDUCTION OF ANAESTHESIA ( 16 patients )
OSTEOTOMY ( 15 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 13 patients )
PAIN ( 6 patients )
SENSORY DISTURBANCE ( 5 patients )
DRUG ABUSE ( 4 patients )
ANAESTHESIA PROCEDURE ( 3 patients )
IN VITRO FERTILISATION ( 3 patients )
DRUG WITHDRAWAL SYNDROME ( 2 patients )
ILL-DEFINED DISORDER ( 2 patients )
MUSCLE RELAXANT THERAPY ( 1 patients )
PNEUMONIA ( 1 patients )
DISCOMFORT ( 1 patients )
SURGERY ( 1 patients )
LIGHT ANAESTHESIA ( 1 patients )
PERIOPERATIVE ANALGESIA ( 1 patients )
POST PROCEDURAL PAIN ( 1 patients )
COLONOSCOPY ( 1 patients )
RETINAL DETACHMENT ( 1 patients )
VARICOSE VEIN OPERATION ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with ANHEDONIA:

TRASYLOL (8239 patients)
ZOMETA (3155 patients)
YAZ (2621 patients)
YASMIN (2447 patients)
HEPARIN (2067 patients)
LASIX (2048 patients)
AREDIA (1868 patients)
METOCLOPRAMIDE (1634 patients)
ASPIRIN (1603 patients)
COUMADIN (1264 patients)
MAGNEVIST (1224 patients)
NITROGLYCERIN (1199 patients)
DIGOXIN (1127 patients)
VIOXX (1125 patients)
LIPITOR (1124 patients)
PROTAMINE SULFATE (1065 patients)
LISINOPRIL (1036 patients)
DROSPIRENONE AND ETHINYL ESTRADIOL (947 patients)
VERSED (891 patients)
ACETYLSALICYLIC ACID SRT (885 patients)
RED BLOOD CELLS (876 patients)
VANCOMYCIN (855 patients)
PROTONIX (840 patients)
FENTANYL (826 patients)
PREDNISONE (825 patients)
PLAVIX (785 patients)
AMBIEN (755 patients)
INSULIN (753 patients)
LEVAQUIN (718 patients)
OMNISCAN (712 patients)
PRILOSEC (702 patients)
ACCUTANE (686 patients)
ZOCOR (686 patients)
NEXIUM (685 patients)
PERCOCET (680 patients)
ATENOLOL (676 patients)
CELEBREX (674 patients)
NORVASC (669 patients)
OXYCONTIN (659 patients)
SYNTHROID (644 patients)
VICODIN (621 patients)
XANAX (621 patients)
TOPROL-XL (620 patients)
LEXAPRO (614 patients)
IBUPROFEN (602 patients)
DEXAMETHASONE (599 patients)
FUROSEMIDE (598 patients)
NEURONTIN (596 patients)
HYDROCHLOROTHIAZIDE (587 patients)
AMOXICILLIN (573 patients)
PREVACID (566 patients)
FOSAMAX (565 patients)
PLATELETS (561 patients)
ZOLOFT (558 patients)
MORPHINE (536 patients)
ALBUTEROL (522 patients)
LIDOCAINE (521 patients)
ATIVAN (514 patients)
COREG (513 patients)
DECADRON (512 patients)
REGLAN (503 patients)
LOPRESSOR (499 patients)
EPINEPHRINE (495 patients)
ANCEF (494 patients)
MANNITOL (487 patients)
POTASSIUM CHLORIDE (480 patients)
LOVENOX (474 patients)
PAXIL (459 patients)
OXYCODONE HCL (458 patients)
OPTIMARK (452 patients)
CHEMOTHERAPEUTICS NOS (446 patients)
WARFARIN SODIUM (433 patients)
AMIODARONE HCL (432 patients)
TAMOXIFEN CITRATE (429 patients)
SIMVASTATIN (425 patients)
DOPAMINE HCL (423 patients)
CLINDAMYCIN (422 patients)
ACETAMINOPHEN (417 patients)
METOPROLOL TARTRATE (413 patients)
CYMBALTA (411 patients)
LORAZEPAM (409 patients)
LORTAB (406 patients)
THALIDOMIDE (402 patients)
RADIATION THERAPY (392 patients)
CHLORHEXIDINE GLUCONATE (390 patients)
ZOFRAN (388 patients)
PERIDEX (386 patients)
EFFEXOR (384 patients)
ZANTAC (383 patients)
CEPHALEXIN (380 patients)
PROHANCE (375 patients)
MULTIHANCE (374 patients)
FRESH FROZEN PLASMA (358 patients)
COLACE (354 patients)
ADVAIR DISKUS 100/50 (350 patients)
CIPROFLOXACIN (349 patients)
FEMARA (347 patients)
FOLIC ACID (342 patients)
DILAUDID (340 patients)
CELEXA (339 patients)
ZITHROMAX (338 patients)
FLEXERIL (338 patients)
PROPOFOL (337 patients)
MULTI-VITAMINS (337 patients)
TAXOTERE (336 patients)
ALPRAZOLAM (335 patients)
XELODA (334 patients)
GABAPENTIN (333 patients)
ARANESP (325 patients)
PEPCID (325 patients)
MILRINONE (324 patients)
ARIMIDEX (324 patients)
WELLBUTRIN (322 patients)
CALCIUM (321 patients)
FLAGYL (320 patients)
ALLOPURINOL (320 patients)
FLUCONAZOLE (318 patients)
OMEPRAZOLE (318 patients)
EPOGEN (316 patients)
DIOVAN (308 patients)
AROMASIN (306 patients)
VITAMIN D (306 patients)
PROZAC (302 patients)
ELAVIL (297 patients)
GLIPIZIDE (295 patients)
LANTUS (295 patients)
CLONIDINE (293 patients)
ZYRTEC (291 patients)
HYDROCODONE (289 patients)
DURAGESIC-100 (287 patients)
GADOLINIUM IN UNSPECIFIED DRUG (287 patients)
COZAAR (286 patients)
SODIUM BICARBONATE (282 patients)
LEVOPHED (280 patients)
CARDIZEM (280 patients)
PROMETHAZINE (279 patients)
DEPAKOTE (279 patients)
METOPROLOL (274 patients)
ALTACE (271 patients)
FASLODEX (271 patients)
ZESTRIL (268 patients)
SPIRONOLACTONE (267 patients)
ALBUMIN (HUMAN) (267 patients)
FLONASE (263 patients)
SEROQUEL (259 patients)
AZITHROMYCIN (256 patients)
AVANDIA (254 patients)
CYTOXAN (248 patients)
SOLU-MEDROL (246 patients)
LEVOTHYROXINE SODIUM (245 patients)
METFORMIN HCL (244 patients)
GLUCOPHAGE (244 patients)
CIPRO (243 patients)
LUPRON (243 patients)
FLOMAX (236 patients)
CEFAZOLIN (235 patients)
METRONIDAZOLE (234 patients)
LYRICA (233 patients)
KEFLEX (232 patients)
PREDNISONE TAB (231 patients)
PRAVACHOL (230 patients)
PROCRIT /00909301/ (227 patients)
TEMAZEPAM (224 patients)
KLONOPIN (222 patients)
BENADRYL (221 patients)
ACYCLOVIR (218 patients)
AVELOX (217 patients)
KLOR-CON (217 patients)
ZETIA (216 patients)
TAXOL (215 patients)
MORPHINE SULFATE (215 patients)
PLASMA (215 patients)
ALLEGRA (214 patients)
CONTRAST MEDIA (213 patients)
AUGMENTIN '125' (212 patients)
DARVOCET-N 100 (212 patients)
HERCEPTIN (208 patients)
NEUPOGEN (208 patients)
PHENYLEPHRINE HCL (207 patients)
GLYBURIDE (206 patients)
MS CONTIN (206 patients)
AMICAR (204 patients)
AVASTIN (203 patients)
POTASSIUM (202 patients)
CALCIUM CHLORIDE (202 patients)
ENALAPRIL MALEATE (202 patients)
SINGULAIR (201 patients)
MAGNESIUM SULFATE (200 patients)
ADRIAMYCIN PFS (200 patients)
CALCIUM CARBONATE (199 patients)
MOTRIN (199 patients)
ACTOS (198 patients)
DIFLUCAN (197 patients)
RENAGEL (196 patients)
IMDUR (195 patients)
PREMARIN (194 patients)
BACTRIM (194 patients)
DIAZEPAM (193 patients)
HYDROCODONE BITARTRATE (192 patients)
LANOXIN (192 patients)
MELPHALAN HYDROCHLORIDE (192 patients)
CRESTOR (191 patients)
CASODEX (191 patients)
ACCUPRIL (187 patients)
VELCADE (186 patients)
RESTORIL (185 patients)
ALDACTONE (184 patients)
NAPROXEN (183 patients)
OXYCODONE (183 patients)
VALIUM (180 patients)
Most common side effects for patients taking ALFENTANIL:
DRUG INTERACTION (75 patients)
DYSTONIA (56 patients)
MYOTONIA (54 patients)
RENAL IMPAIRMENT (42 patients)
SINUS TACHYCARDIA (34 patients)
AGITATION (32 patients)
BACK PAIN (28 patients)
TOXIC EPIDERMAL NECROLYSIS (28 patients)
INFECTION (26 patients)
CARDIAC ARREST (26 patients)
DRUG WITHDRAWAL SYNDROME (26 patients)
THERAPEUTIC AGENT TOXICITY (24 patients)
DRUG EFFECT DECREASED (24 patients)
BRADYCARDIA (23 patients)
TACHYCARDIA (19 patients)
MYOCLONUS (19 patients)
STARING (19 patients)
ANAPHYLACTIC SHOCK (18 patients)
HYPOTENSION (18 patients)
DRUG TOXICITY (18 patients)
MULTI-ORGAN FAILURE (17 patients)
VENTRICULAR FIBRILLATION (16 patients)
BRONCHOSPASM (16 patients)
DEATH (16 patients)
ALANINE AMINOTRANSFERASE INCREASED (15 patients)
OXYGEN SATURATION DECREASED (15 patients)
DRUG EXPOSURE DURING PREGNANCY (15 patients)
HEPATITIS (15 patients)
RESTLESSNESS (14 patients)
PANIC REACTION (14 patients)
LIVER FUNCTION TEST ABNORMAL (14 patients)
ABDOMINAL PAIN (13 patients)
WHITE BLOOD CELL COUNT INCREASED (13 patients)
TUBULOINTERSTITIAL NEPHRITIS (13 patients)
DRUG INEFFECTIVE (13 patients)
DRUG RASH WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS (13 patients)
ANAPHYLACTIC REACTION (12 patients)
HYPERHIDROSIS (12 patients)
NAUSEA (12 patients)
RENAL FAILURE ACUTE (12 patients)
GASTROINTESTINAL HAEMORRHAGE (12 patients)
OEDEMA PERIPHERAL (12 patients)
AGGRESSION (11 patients)
COMA (11 patients)
CYANOSIS (11 patients)
ESCHERICHIA INFECTION (11 patients)
SOMNOLENCE (11 patients)
HAEMOGLOBIN DECREASED (11 patients)
PLEURAL EFFUSION (10 patients)
BLOOD PHOSPHORUS INCREASED (10 patients)
HYPERVENTILATION (10 patients)
CONDITION AGGRAVATED (10 patients)
DISEASE PROGRESSION (10 patients)
HYPOXIA (10 patients)
FEELING ABNORMAL (10 patients)
PULMONARY OEDEMA (9 patients)
SPEECH DISORDER (9 patients)
MYALGIA (9 patients)
ATRIAL FIBRILLATION (9 patients)
PILOERECTION (9 patients)
CAESAREAN SECTION (9 patients)
SEROTONIN SYNDROME (9 patients)
CATATONIA (9 patients)
POST PROCEDURAL COMPLICATION (9 patients)
DYSPNOEA (9 patients)
MYDRIASIS (9 patients)
HEPATIC FAILURE (9 patients)
ACUTE RESPIRATORY DISTRESS SYNDROME (8 patients)
AKATHISIA (8 patients)
ANAESTHETIC COMPLICATION (8 patients)
LACERATION (8 patients)
BLOOD ALBUMIN DECREASED (8 patients)
BLOOD BILIRUBIN INCREASED (8 patients)
BLOOD CALCIUM INCREASED (8 patients)
BRAIN OEDEMA (8 patients)
PNEUMONIA (8 patients)
PUPILLARY REFLEX IMPAIRED (8 patients)
ELECTROCARDIOGRAM QT PROLONGED (8 patients)
RHABDOMYOLYSIS (8 patients)
BLISTER (7 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (7 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (7 patients)
HYPERSENSITIVITY (7 patients)
PYREXIA (7 patients)
C-REACTIVE PROTEIN INCREASED (7 patients)
PARAESTHESIA (7 patients)
VOMITING (7 patients)
PREMATURE RUPTURE OF MEMBRANES (7 patients)
SCLERODERMA (7 patients)
RENAL FAILURE (7 patients)
EXTENSOR PLANTAR RESPONSE (7 patients)
FATIGUE (7 patients)
HAEMATEMESIS (7 patients)
SLEEP DISORDER (7 patients)
PREMATURE LABOUR (7 patients)
ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED (6 patients)
AMNESIA (6 patients)
PEMPHIGOID (6 patients)
PROCEDURAL COMPLICATION (6 patients)
ASCITES INFECTION (6 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (6 patients)
HYPOCOAGULABLE STATE (6 patients)
BLOOD PRESSURE DECREASED (6 patients)
IDIOPATHIC THROMBOCYTOPENIC PURPURA (6 patients)
VENTRICULAR TACHYCARDIA (6 patients)
HYPERGLYCAEMIA (6 patients)
WOUND SECRETION (6 patients)
ENTEROCOCCAL INFECTION (6 patients)
MOVEMENT DISORDER (6 patients)
SEPSIS (6 patients)
NO THERAPEUTIC RESPONSE (6 patients)
GLASGOW COMA SCALE ABNORMAL (6 patients)
ABDOMINAL SEPSIS (5 patients)
HYPOTONIA (5 patients)
HYPERREFLEXIA (5 patients)
APHASIA (5 patients)
ASCITES (5 patients)
HYPERPARATHYROIDISM (5 patients)
HYPOKALAEMIA (5 patients)
CARDIO-RESPIRATORY ARREST (5 patients)
UNRESPONSIVE TO STIMULI (5 patients)
THROMBOCYTOPENIA (5 patients)
PROPOFOL INFUSION SYNDROME (5 patients)
ELECTROCARDIOGRAM ST SEGMENT DEPRESSION (5 patients)
SCREAMING (5 patients)
ISCHAEMIC STROKE (5 patients)
FALL (5 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (5 patients)
TREMOR (5 patients)
HEMIPLEGIA (5 patients)
SMALL INTESTINAL HAEMORRHAGE (5 patients)
NEUTROPENIA (4 patients)
ACCIDENTAL OVERDOSE (4 patients)
RESUSCITATION (4 patients)
AIRWAY COMPLICATION OF ANAESTHESIA (4 patients)
TRANSAMINASES INCREASED (4 patients)
ARRHYTHMIA (4 patients)
ARTHRALGIA (4 patients)
NO ADVERSE EVENT (4 patients)
BLOOD TRIGLYCERIDES INCREASED (4 patients)
INJURY (4 patients)
MATERNAL DRUGS AFFECTING FOETUS (4 patients)
RESPIRATORY DEPRESSION (4 patients)
MOTOR DYSFUNCTION (4 patients)
MUSCLE RIGIDITY (4 patients)
LABILE BLOOD PRESSURE (4 patients)
CELLULITIS (4 patients)
DELAYED RECOVERY FROM ANAESTHESIA (4 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (4 patients)
HYPERTENSION (4 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (4 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (4 patients)
PULMONARY EMBOLISM (4 patients)
ECTOPIC PREGNANCY (4 patients)
RASH ERYTHEMATOUS (4 patients)
MELAENA (4 patients)
FOETAL MALPRESENTATION (4 patients)
NEUTROPHILIA (4 patients)
GRAND MAL CONVULSION (4 patients)
SUBARACHNOID HAEMORRHAGE (4 patients)
OEDEMA (4 patients)
ABORTION INDUCED (3 patients)
ANHEDONIA (3 patients)
VARICOSE VEIN OPERATION (3 patients)
PAIN (3 patients)
ANXIETY (3 patients)
APALLIC SYNDROME (3 patients)
MICROSTOMIA (3 patients)
RESPIRATORY FAILURE (3 patients)
BLOOD CREATININE INCREASED (3 patients)
UNEVALUABLE EVENT (3 patients)
PANIC ATTACK (3 patients)
BLOOD POTASSIUM DECREASED (3 patients)
BONE DISORDER (3 patients)
BRAIN DEATH (3 patients)
CARDIAC DISORDER (3 patients)
METABOLIC ACIDOSIS (3 patients)
SKIN REACTION (3 patients)
PANCREATIC ABSCESS (3 patients)
CEREBRAL HAEMORRHAGE (3 patients)
CEREBRAL ISCHAEMIA (3 patients)
CEREBROVASCULAR ACCIDENT (3 patients)
CHOLESTASIS (3 patients)
ORGAN FAILURE (3 patients)
PANCREATITIS (3 patients)
CONVULSION (3 patients)
CYTOLYTIC HEPATITIS (3 patients)
TUMOUR LYSIS SYNDROME (3 patients)
PANCREATIC NECROSIS (3 patients)
DEHYDRATION (3 patients)
DEPRESSION (3 patients)
PROTHROMBIN TIME PROLONGED (3 patients)
DRUG HYPERSENSITIVITY (3 patients)
HYPOGLYCAEMIA NEONATAL (3 patients)
DYSPHASIA (3 patients)
DYSPHONIA (3 patients)
RENAL INJURY (3 patients)
LOCALISED OEDEMA (3 patients)
ELECTROMECHANICAL DISSOCIATION (3 patients)
RAYNAUD'S PHENOMENON (3 patients)
ERYTHEMA (3 patients)
FACE OEDEMA (3 patients)
FEAR (3 patients)
SEX CHROMOSOME ABNORMALITY (3 patients)
SKIN DISCOLOURATION (3 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (3 patients)
HAEMATOMA (3 patients)
HAEMODIALYSIS (3 patients)
THERAPY NON-RESPONDER (3 patients)
HEART RATE INCREASED (3 patients)

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