About this FactMed analysis covering adverse side effect reports of ALFENTANIL patients who developed SURGERY.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 2 individuals taking ALFENTANIL reported SURGERY to the FDA. A total of 427 ALFENTANIL drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between ALFENTANIL and SURGERY. In doing so, we compare ALFENTANIL with other drugs that cause SURGERY, to help you evaluate whether or not ALFENTANIL causes SURGERY. Likewise, this page shows the most highly-reported side effects of ALFENTANIL, so you can see if SURGERY ranks among ALFENTANIL's most well-known side effects.
Summary Statistics
Reports of ALFENTANIL causing SURGERY: 2
Reports of any side effect of ALFENTANIL : 427
Percentage of ALFENTANIL patients where SURGERY is a reported side effect: 0.4684%

FDA reports of any drug causing SURGERY : 12034
Average percentage for all medicated patients where SURGERY is reported as a complication: 0.0754%

Physician opinion on ALFENTANIL as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing ALFENTANIL:
ANAESTHESIA ( 63 patients )
GENERAL ANAESTHESIA ( 52 patients )
SEDATION ( 17 patients )
DRUG USE FOR UNKNOWN INDICATION ( 16 patients )
INDUCTION OF ANAESTHESIA ( 16 patients )
OSTEOTOMY ( 15 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 13 patients )
PAIN ( 6 patients )
SENSORY DISTURBANCE ( 5 patients )
DRUG ABUSE ( 4 patients )
ANAESTHESIA PROCEDURE ( 3 patients )
IN VITRO FERTILISATION ( 3 patients )
DRUG WITHDRAWAL SYNDROME ( 2 patients )
ILL-DEFINED DISORDER ( 2 patients )
MUSCLE RELAXANT THERAPY ( 1 patients )
PNEUMONIA ( 1 patients )
DISCOMFORT ( 1 patients )
SURGERY ( 1 patients )
LIGHT ANAESTHESIA ( 1 patients )
PERIOPERATIVE ANALGESIA ( 1 patients )
POST PROCEDURAL PAIN ( 1 patients )
COLONOSCOPY ( 1 patients )
RETINAL DETACHMENT ( 1 patients )
VARICOSE VEIN OPERATION ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with SURGERY:

FORTEO (1076 patients)
ZOMETA (972 patients)
REMICADE (853 patients)
DIGOXIN (803 patients)
ASPIRIN (740 patients)
AVONEX (623 patients)
LIPITOR (532 patients)
AREDIA (503 patients)
NEXIUM (493 patients)
LASIX (473 patients)
TYSABRI (447 patients)
ENBREL (444 patients)
LYRICA (439 patients)
HUMIRA (424 patients)
GLEEVEC (403 patients)
CELEBREX (400 patients)
SEROQUEL (394 patients)
CHANTIX (380 patients)
COUMADIN (365 patients)
NEURONTIN (359 patients)
LISINOPRIL (352 patients)
DIOVAN (345 patients)
FOSAMAX (339 patients)
PREDNISONE (337 patients)
FUROSEMIDE (322 patients)
OXYCONTIN (308 patients)
CYMBALTA (295 patients)
CALCIUM (295 patients)
VIOXX (284 patients)
PRILOSEC (282 patients)
XANAX (277 patients)
PROTONIX (277 patients)
PLAVIX (276 patients)
POTASSIUM CHLORIDE (269 patients)
SYNTHROID (263 patients)
AMBIEN (253 patients)
DURAGESIC-100 (246 patients)
ZOLOFT (245 patients)
ATENOLOL (235 patients)
VITAMIN D (233 patients)
CLOZARIL (232 patients)
GABAPENTIN (227 patients)
NEORAL (223 patients)
OMEPRAZOLE (223 patients)
TOPROL-XL (222 patients)
METHOTREXATE (221 patients)
ALBUTEROL (219 patients)
ZOCOR (209 patients)
ARIMIDEX (202 patients)
EXJADE (202 patients)
COREG (201 patients)
PREDNISOLONE (201 patients)
FOLIC ACID (198 patients)
SIMVASTATIN (195 patients)
LORTAB (193 patients)
CRESTOR (192 patients)
NORVASC (190 patients)
PERCOCET (189 patients)
LANTUS (188 patients)
WARFARIN SODIUM (188 patients)
PREMARIN (179 patients)
PREVACID (179 patients)
LEVAQUIN (174 patients)
HYDROCODONE (174 patients)
ATIVAN (171 patients)
HUMALOG (169 patients)
DIOVAN HCT (169 patients)
LORAZEPAM (169 patients)
DECADRON (168 patients)
LEXAPRO (166 patients)
NITROGLYCERIN (160 patients)
LEVOTHYROXINE SODIUM (158 patients)
DEXAMETHASONE (154 patients)
METFORMIN HCL (152 patients)
SANDOSTATIN LAR (151 patients)
MORPHINE (151 patients)
SPIRONOLACTONE (151 patients)
ALPRAZOLAM (147 patients)
VICODIN (145 patients)
PAXIL (144 patients)
FEMARA (143 patients)
ACLASTA (143 patients)
ADVAIR DISKUS 100/50 (140 patients)
TAXOTERE (140 patients)
OXYCODONE HCL (138 patients)
HYDROCHLOROTHIAZIDE (137 patients)
SPIRIVA (134 patients)
MULTI-VITAMINS (131 patients)
INSULIN (129 patients)
VOLTAREN (129 patients)
CHEMOTHERAPEUTICS NOS (128 patients)
PROZAC (125 patients)
POTASSIUM (125 patients)
CYCLOSPORINE (124 patients)
METOPROLOL TARTRATE (124 patients)
BYETTA (123 patients)
ZOLEDRONIC ACID (123 patients)
TRACLEER (123 patients)
TAMOXIFEN CITRATE (122 patients)
ZELNORM (120 patients)
IBUPROFEN (116 patients)
ACETAMINOPHEN (115 patients)
PREDNISONE TAB (113 patients)
AVANDIA (112 patients)
CEPHALEXIN (110 patients)
EFFEXOR (110 patients)
KLOR-CON (109 patients)
SANDIMMUNE (108 patients)
AMOXICILLIN (107 patients)
BEXTRA (107 patients)
ALDACTONE (106 patients)
WELLBUTRIN (105 patients)
LOVENOX (104 patients)
METOPROLOL (104 patients)
DIAZEPAM (104 patients)
CLONIDINE (104 patients)
MORPHINE SULFATE (103 patients)
ALLOPURINOL (103 patients)
HYDROCODONE BITARTRATE (102 patients)
LETAIRIS (102 patients)
EXELON (102 patients)
CLONAZEPAM (101 patients)
KLONOPIN (101 patients)
TEGRETOL (101 patients)
MULTI-VITAMIN (100 patients)
DIFLUCAN (99 patients)
ATROVENT (99 patients)
COLACE (99 patients)
LOPRESSOR (98 patients)
FLEXERIL (98 patients)
CARBOPLATIN (97 patients)
VIAGRA (96 patients)
XELODA (96 patients)
VALIUM (96 patients)
MYCOPHENOLATE MOFETIL (95 patients)
THALIDOMIDE (95 patients)
CARDIZEM (93 patients)
OXYCODONE (93 patients)
ARANESP (92 patients)
CELEXA (92 patients)
TRAZODONE HCL (91 patients)
EVISTA (90 patients)
VITAMIN B-12 (89 patients)
SKELAXIN (88 patients)
TRAMADOL HCL (88 patients)
STEROIDS NOS (88 patients)
ZYPREXA (88 patients)
ZETIA (88 patients)
TEMAZEPAM (86 patients)
FLOMAX (86 patients)
ZANTAC (86 patients)
GLIPIZIDE (85 patients)
COMPAZINE (85 patients)
DILAUDID (85 patients)
ALTACE (85 patients)
CARVEDILOL (84 patients)
SINGULAIR (84 patients)
ZYRTEC (83 patients)
AMLODIPINE (83 patients)
MS CONTIN (82 patients)
TAXOL (82 patients)
ENALAPRIL MALEATE (80 patients)
PROMETHAZINE (80 patients)
XALATAN (80 patients)
CIPRO (79 patients)
TYLENOL (78 patients)
ACTOS (78 patients)
FLAGYL (78 patients)
HEPARIN (77 patients)
NEXAVAR (76 patients)
SOMA (76 patients)
FENTANYL (76 patients)
ZOFRAN (75 patients)
CALCIUM CARBONATE (74 patients)
REVLIMID (74 patients)
ALENDRONATE SODIUM (74 patients)
CIALIS (73 patients)
EFFEXOR XR (73 patients)
TRILEPTAL (73 patients)
AZITHROMYCIN (72 patients)
BACLOFEN (72 patients)
CIPROFLOXACIN (72 patients)
HERCEPTIN (72 patients)
REGLAN (71 patients)
IRON (71 patients)
FERROUS SULFATE TAB (71 patients)
TYLENOL (CAPLET) (71 patients)
CELLCEPT (71 patients)
FLUCONAZOLE (70 patients)
ALL OTHER THERAPEUTIC PRODUCTS (70 patients)
TOPAMAX (69 patients)
GEMZAR (69 patients)
VANCOMYCIN (69 patients)
RISPERDAL (69 patients)
LEVOXYL (68 patients)
KEFLEX (68 patients)
NYSTATIN (67 patients)
AROMASIN (67 patients)
SIMULECT (67 patients)
PAMIDRONATE DISODIUM (66 patients)
K-DUR (66 patients)
AMIODARONE HCL (66 patients)
ASCORBIC ACID (66 patients)
VERAPAMIL (66 patients)
VITAMIN E (65 patients)
RADIATION THERAPY (65 patients)
GLUCOPHAGE (65 patients)
FISH OIL (64 patients)
CYTOXAN (64 patients)
BETASERON (64 patients)
Most common side effects for patients taking ALFENTANIL:
DRUG INTERACTION (75 patients)
DYSTONIA (56 patients)
MYOTONIA (54 patients)
RENAL IMPAIRMENT (42 patients)
SINUS TACHYCARDIA (34 patients)
AGITATION (32 patients)
BACK PAIN (28 patients)
TOXIC EPIDERMAL NECROLYSIS (28 patients)
INFECTION (26 patients)
CARDIAC ARREST (26 patients)
DRUG WITHDRAWAL SYNDROME (26 patients)
THERAPEUTIC AGENT TOXICITY (24 patients)
DRUG EFFECT DECREASED (24 patients)
BRADYCARDIA (23 patients)
TACHYCARDIA (19 patients)
MYOCLONUS (19 patients)
STARING (19 patients)
ANAPHYLACTIC SHOCK (18 patients)
HYPOTENSION (18 patients)
DRUG TOXICITY (18 patients)
MULTI-ORGAN FAILURE (17 patients)
VENTRICULAR FIBRILLATION (16 patients)
BRONCHOSPASM (16 patients)
DEATH (16 patients)
ALANINE AMINOTRANSFERASE INCREASED (15 patients)
OXYGEN SATURATION DECREASED (15 patients)
DRUG EXPOSURE DURING PREGNANCY (15 patients)
HEPATITIS (15 patients)
RESTLESSNESS (14 patients)
PANIC REACTION (14 patients)
LIVER FUNCTION TEST ABNORMAL (14 patients)
ABDOMINAL PAIN (13 patients)
WHITE BLOOD CELL COUNT INCREASED (13 patients)
TUBULOINTERSTITIAL NEPHRITIS (13 patients)
DRUG INEFFECTIVE (13 patients)
DRUG RASH WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS (13 patients)
ANAPHYLACTIC REACTION (12 patients)
HYPERHIDROSIS (12 patients)
NAUSEA (12 patients)
RENAL FAILURE ACUTE (12 patients)
GASTROINTESTINAL HAEMORRHAGE (12 patients)
OEDEMA PERIPHERAL (12 patients)
AGGRESSION (11 patients)
COMA (11 patients)
CYANOSIS (11 patients)
ESCHERICHIA INFECTION (11 patients)
SOMNOLENCE (11 patients)
HAEMOGLOBIN DECREASED (11 patients)
PLEURAL EFFUSION (10 patients)
BLOOD PHOSPHORUS INCREASED (10 patients)
HYPERVENTILATION (10 patients)
CONDITION AGGRAVATED (10 patients)
DISEASE PROGRESSION (10 patients)
HYPOXIA (10 patients)
FEELING ABNORMAL (10 patients)
PULMONARY OEDEMA (9 patients)
SPEECH DISORDER (9 patients)
MYALGIA (9 patients)
ATRIAL FIBRILLATION (9 patients)
PILOERECTION (9 patients)
CAESAREAN SECTION (9 patients)
SEROTONIN SYNDROME (9 patients)
CATATONIA (9 patients)
POST PROCEDURAL COMPLICATION (9 patients)
DYSPNOEA (9 patients)
MYDRIASIS (9 patients)
HEPATIC FAILURE (9 patients)
ACUTE RESPIRATORY DISTRESS SYNDROME (8 patients)
AKATHISIA (8 patients)
ANAESTHETIC COMPLICATION (8 patients)
LACERATION (8 patients)
BLOOD ALBUMIN DECREASED (8 patients)
BLOOD BILIRUBIN INCREASED (8 patients)
BLOOD CALCIUM INCREASED (8 patients)
BRAIN OEDEMA (8 patients)
PNEUMONIA (8 patients)
PUPILLARY REFLEX IMPAIRED (8 patients)
ELECTROCARDIOGRAM QT PROLONGED (8 patients)
RHABDOMYOLYSIS (8 patients)
BLISTER (7 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (7 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (7 patients)
HYPERSENSITIVITY (7 patients)
PYREXIA (7 patients)
C-REACTIVE PROTEIN INCREASED (7 patients)
PARAESTHESIA (7 patients)
VOMITING (7 patients)
PREMATURE RUPTURE OF MEMBRANES (7 patients)
SCLERODERMA (7 patients)
RENAL FAILURE (7 patients)
EXTENSOR PLANTAR RESPONSE (7 patients)
FATIGUE (7 patients)
HAEMATEMESIS (7 patients)
SLEEP DISORDER (7 patients)
PREMATURE LABOUR (7 patients)
ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED (6 patients)
AMNESIA (6 patients)
PEMPHIGOID (6 patients)
PROCEDURAL COMPLICATION (6 patients)
ASCITES INFECTION (6 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (6 patients)
HYPOCOAGULABLE STATE (6 patients)
BLOOD PRESSURE DECREASED (6 patients)
IDIOPATHIC THROMBOCYTOPENIC PURPURA (6 patients)
VENTRICULAR TACHYCARDIA (6 patients)
HYPERGLYCAEMIA (6 patients)
WOUND SECRETION (6 patients)
ENTEROCOCCAL INFECTION (6 patients)
MOVEMENT DISORDER (6 patients)
SEPSIS (6 patients)
NO THERAPEUTIC RESPONSE (6 patients)
GLASGOW COMA SCALE ABNORMAL (6 patients)
ABDOMINAL SEPSIS (5 patients)
HYPOTONIA (5 patients)
HYPERREFLEXIA (5 patients)
APHASIA (5 patients)
ASCITES (5 patients)
HYPERPARATHYROIDISM (5 patients)
HYPOKALAEMIA (5 patients)
CARDIO-RESPIRATORY ARREST (5 patients)
UNRESPONSIVE TO STIMULI (5 patients)
THROMBOCYTOPENIA (5 patients)
PROPOFOL INFUSION SYNDROME (5 patients)
ELECTROCARDIOGRAM ST SEGMENT DEPRESSION (5 patients)
SCREAMING (5 patients)
ISCHAEMIC STROKE (5 patients)
FALL (5 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (5 patients)
TREMOR (5 patients)
HEMIPLEGIA (5 patients)
SMALL INTESTINAL HAEMORRHAGE (5 patients)
NEUTROPENIA (4 patients)
ACCIDENTAL OVERDOSE (4 patients)
RESUSCITATION (4 patients)
AIRWAY COMPLICATION OF ANAESTHESIA (4 patients)
TRANSAMINASES INCREASED (4 patients)
ARRHYTHMIA (4 patients)
ARTHRALGIA (4 patients)
NO ADVERSE EVENT (4 patients)
BLOOD TRIGLYCERIDES INCREASED (4 patients)
INJURY (4 patients)
MATERNAL DRUGS AFFECTING FOETUS (4 patients)
RESPIRATORY DEPRESSION (4 patients)
MOTOR DYSFUNCTION (4 patients)
MUSCLE RIGIDITY (4 patients)
LABILE BLOOD PRESSURE (4 patients)
CELLULITIS (4 patients)
DELAYED RECOVERY FROM ANAESTHESIA (4 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (4 patients)
HYPERTENSION (4 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (4 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (4 patients)
PULMONARY EMBOLISM (4 patients)
ECTOPIC PREGNANCY (4 patients)
RASH ERYTHEMATOUS (4 patients)
MELAENA (4 patients)
FOETAL MALPRESENTATION (4 patients)
NEUTROPHILIA (4 patients)
GRAND MAL CONVULSION (4 patients)
SUBARACHNOID HAEMORRHAGE (4 patients)
OEDEMA (4 patients)
ABORTION INDUCED (3 patients)
ANHEDONIA (3 patients)
VARICOSE VEIN OPERATION (3 patients)
PAIN (3 patients)
ANXIETY (3 patients)
APALLIC SYNDROME (3 patients)
MICROSTOMIA (3 patients)
RESPIRATORY FAILURE (3 patients)
BLOOD CREATININE INCREASED (3 patients)
UNEVALUABLE EVENT (3 patients)
PANIC ATTACK (3 patients)
BLOOD POTASSIUM DECREASED (3 patients)
BONE DISORDER (3 patients)
BRAIN DEATH (3 patients)
CARDIAC DISORDER (3 patients)
METABOLIC ACIDOSIS (3 patients)
SKIN REACTION (3 patients)
PANCREATIC ABSCESS (3 patients)
CEREBRAL HAEMORRHAGE (3 patients)
CEREBRAL ISCHAEMIA (3 patients)
CEREBROVASCULAR ACCIDENT (3 patients)
CHOLESTASIS (3 patients)
ORGAN FAILURE (3 patients)
PANCREATITIS (3 patients)
CONVULSION (3 patients)
CYTOLYTIC HEPATITIS (3 patients)
TUMOUR LYSIS SYNDROME (3 patients)
PANCREATIC NECROSIS (3 patients)
DEHYDRATION (3 patients)
DEPRESSION (3 patients)
PROTHROMBIN TIME PROLONGED (3 patients)
DRUG HYPERSENSITIVITY (3 patients)
HYPOGLYCAEMIA NEONATAL (3 patients)
DYSPHASIA (3 patients)
DYSPHONIA (3 patients)
RENAL INJURY (3 patients)
LOCALISED OEDEMA (3 patients)
ELECTROMECHANICAL DISSOCIATION (3 patients)
RAYNAUD'S PHENOMENON (3 patients)
ERYTHEMA (3 patients)
FACE OEDEMA (3 patients)
FEAR (3 patients)
SEX CHROMOSOME ABNORMALITY (3 patients)
SKIN DISCOLOURATION (3 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (3 patients)
HAEMATOMA (3 patients)
HAEMODIALYSIS (3 patients)
THERAPY NON-RESPONDER (3 patients)
HEART RATE INCREASED (3 patients)

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