About this FactMed analysis covering adverse side effect reports of ALFENTANIL patients who developed THROMBOCYTOPENIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 5 individuals taking ALFENTANIL reported THROMBOCYTOPENIA to the FDA. A total of 427 ALFENTANIL drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between ALFENTANIL and THROMBOCYTOPENIA. In doing so, we compare ALFENTANIL with other drugs that cause THROMBOCYTOPENIA, to help you evaluate whether or not ALFENTANIL causes THROMBOCYTOPENIA. Likewise, this page shows the most highly-reported side effects of ALFENTANIL, so you can see if THROMBOCYTOPENIA ranks among ALFENTANIL's most well-known side effects.
Summary Statistics
Reports of ALFENTANIL causing THROMBOCYTOPENIA: 5
Reports of any side effect of ALFENTANIL : 427
Percentage of ALFENTANIL patients where THROMBOCYTOPENIA is a reported side effect: 1.1710%

FDA reports of any drug causing THROMBOCYTOPENIA : 37390
Average percentage for all medicated patients where THROMBOCYTOPENIA is reported as a complication: 0.2343%

Physician opinion on ALFENTANIL as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing ALFENTANIL:
ANAESTHESIA ( 63 patients )
GENERAL ANAESTHESIA ( 52 patients )
SEDATION ( 17 patients )
DRUG USE FOR UNKNOWN INDICATION ( 16 patients )
INDUCTION OF ANAESTHESIA ( 16 patients )
OSTEOTOMY ( 15 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 13 patients )
PAIN ( 6 patients )
SENSORY DISTURBANCE ( 5 patients )
DRUG ABUSE ( 4 patients )
ANAESTHESIA PROCEDURE ( 3 patients )
IN VITRO FERTILISATION ( 3 patients )
DRUG WITHDRAWAL SYNDROME ( 2 patients )
ILL-DEFINED DISORDER ( 2 patients )
MUSCLE RELAXANT THERAPY ( 1 patients )
PNEUMONIA ( 1 patients )
DISCOMFORT ( 1 patients )
SURGERY ( 1 patients )
LIGHT ANAESTHESIA ( 1 patients )
PERIOPERATIVE ANALGESIA ( 1 patients )
POST PROCEDURAL PAIN ( 1 patients )
COLONOSCOPY ( 1 patients )
RETINAL DETACHMENT ( 1 patients )
VARICOSE VEIN OPERATION ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with THROMBOCYTOPENIA:

HEPARIN SODIUM INJECTION (4057 patients)
ASPIRIN (3010 patients)
REVLIMID (2931 patients)
DEXAMETHASONE (2402 patients)
LASIX (2000 patients)
PREDNISONE (1949 patients)
OMEPRAZOLE (1689 patients)
NPLATE (1653 patients)
CYCLOPHOSPHAMIDE (1515 patients)
VELCADE (1495 patients)
ACETAMINOPHEN (1483 patients)
ZOMETA (1451 patients)
CISPLATIN (1433 patients)
CARBOPLATIN (1423 patients)
FUROSEMIDE (1327 patients)
ALLOPURINOL (1293 patients)
METHOTREXATE (1215 patients)
HEPARIN (1202 patients)
FOLIC ACID (1184 patients)
PREDNISOLONE (1095 patients)
NEXIUM (1091 patients)
FLUOROURACIL (1068 patients)
POTASSIUM CHLORIDE (957 patients)
LOVENOX (939 patients)
COUMADIN (932 patients)
LISINOPRIL (931 patients)
SIMVASTATIN (918 patients)
PLAVIX (908 patients)
ZOFRAN (902 patients)
AREDIA (892 patients)
PROTONIX (889 patients)
DECADRON (880 patients)
VIOXX (877 patients)
LIPITOR (872 patients)
VANCOMYCIN (869 patients)
RITUXIMAB (857 patients)
PREDNISONE TAB (847 patients)
ETOPOSIDE (805 patients)
ACYCLOVIR (800 patients)
CYTARABINE (783 patients)
FOSAMAX (771 patients)
DIGOXIN (733 patients)
FLUCONAZOLE (730 patients)
VINCRISTINE (721 patients)
ATENOLOL (717 patients)
LEVOTHYROXINE SODIUM (717 patients)
KEPPRA (709 patients)
OXYCONTIN (703 patients)
PRILOSEC (689 patients)
HEPARIN SODIUM (674 patients)
AMBIEN (673 patients)
NEUPOGEN (672 patients)
ARANESP (660 patients)
DOXORUBICIN HCL (659 patients)
LORAZEPAM (658 patients)
MORPHINE (657 patients)
GLEEVEC (652 patients)
BACTRIM (650 patients)
OXALIPLATIN (643 patients)
SUTENT (642 patients)
ATIVAN (640 patients)
SYNTHROID (629 patients)
XANAX (619 patients)
NEURONTIN (611 patients)
NORVASC (611 patients)
GEMCITABINE (605 patients)
WARFARIN SODIUM (604 patients)
REMICADE (587 patients)
CYCLOSPORINE (586 patients)
THALIDOMIDE (585 patients)
LEVAQUIN (585 patients)
RIBAVIRIN (576 patients)
ALBUTEROL (573 patients)
PEGASYS (572 patients)
CIPROFLOXACIN (568 patients)
COMPAZINE (568 patients)
GEMZAR (554 patients)
EXJADE (554 patients)
IBUPROFEN (552 patients)
GABAPENTIN (549 patients)
HYDROCHLOROTHIAZIDE (542 patients)
SOLU-MEDROL (541 patients)
OXYCODONE HCL (532 patients)
SEROQUEL (531 patients)
METHYLPREDNISOLONE (524 patients)
METOPROLOL TARTRATE (520 patients)
INSULIN (519 patients)
ZOCOR (510 patients)
ONDANSETRON (496 patients)
VICODIN (492 patients)
LYRICA (488 patients)
PANTOPRAZOLE (488 patients)
AVASTIN (485 patients)
DIFLUCAN (482 patients)
LANSOPRAZOLE (479 patients)
AMLODIPINE (477 patients)
FAMOTIDINE (476 patients)
RAMIPRIL (473 patients)
VIDAZA (473 patients)
MULTI-VITAMINS (472 patients)
ZOLOFT (471 patients)
CORTICOSTEROIDS (468 patients)
PERCOCET (464 patients)
CLOZARIL (464 patients)
METFORMIN HCL (458 patients)
RISPERDAL (457 patients)
FENTANYL (452 patients)
ZYVOX (450 patients)
AUGMENTIN '125' (448 patients)
RANITIDINE (444 patients)
PACLITAXEL (439 patients)
PREVACID (436 patients)
XELODA (435 patients)
ENOXAPARIN SODIUM (431 patients)
TOPROL-XL (431 patients)
VITAMIN B-12 (431 patients)
DEXAMETHASONE TAB (430 patients)
ALDACTONE (429 patients)
PANTOPRAZOLE SODIUM (424 patients)
NEULASTA (423 patients)
NEORAL (419 patients)
LANTUS (419 patients)
DEPAKENE (416 patients)
PROCRIT (403 patients)
CELEBREX (400 patients)
ZANTAC (395 patients)
TAXOL (395 patients)
NITROGLYCERIN (392 patients)
VITAMIN D (390 patients)
CAPECITABINE (389 patients)
ROCEPHIN (388 patients)
ALIMTA (382 patients)
SPIRONOLACTONE (382 patients)
DURAGESIC-100 (380 patients)
ZYPREXA (378 patients)
MORPHINE SULFATE (378 patients)
BEVACIZUMAB (373 patients)
LEVOFLOXACIN (370 patients)
FERROUS SULFATE TAB (365 patients)
COREG (361 patients)
COLACE (361 patients)
LEXAPRO (361 patients)
HUMIRA (357 patients)
MYCOPHENOLATE MOFETIL (356 patients)
LEUCOVORIN CALCIUM (356 patients)
EPOGEN (355 patients)
AMOXICILLIN (353 patients)
COPEGUS (351 patients)
FLAGYL (350 patients)
LOPRESSOR (348 patients)
METOPROLOL (346 patients)
DILAUDID (345 patients)
CETUXIMAB (343 patients)
DIOVAN (338 patients)
METRONIDAZOLE (338 patients)
MAGNESIUM OXIDE (336 patients)
CALCIUM CARBONATE (336 patients)
ADRIAMYCIN PFS (333 patients)
REOPRO (332 patients)
MABTHERA (330 patients)
RADIATION THERAPY (328 patients)
CYTOXAN (327 patients)
DEPAKOTE (326 patients)
TRAMADOL HCL (325 patients)
METOCLOPRAMIDE (325 patients)
PROGRAF (324 patients)
LORTAB (324 patients)
TEMOZOLOMIDE (323 patients)
PEPCID (323 patients)
PAXIL (323 patients)
TASIGNA (321 patients)
LACTULOSE (319 patients)
ALPRAZOLAM (318 patients)
NYSTATIN (316 patients)
VALTREX (316 patients)
CLONAZEPAM (314 patients)
NEXAVAR (314 patients)
MELPHALAN HYDROCHLORIDE (313 patients)
CITALOPRAM HYDROBROMIDE (313 patients)
ENALAPRIL MALEATE (309 patients)
CLOPIDOGREL (308 patients)
CALCIUM (307 patients)
REGLAN (304 patients)
TAXOTERE (304 patients)
TEMODAL (301 patients)
DOCETAXEL (301 patients)
SUNITINIB MALATE (299 patients)
SODIUM CHLORIDE (296 patients)
VALPROATE SODIUM (295 patients)
PARACETAMOL (295 patients)
CRESTOR (294 patients)
RITUXAN (291 patients)
ACCUTANE (290 patients)
MS CONTIN (288 patients)
THALOMID (284 patients)
IRINOTECAN HCL (283 patients)
HYDROCORTISONE (282 patients)
KYTRIL (280 patients)
LAMICTAL (278 patients)
BISOPROLOL FUMARATE (278 patients)
ASCORBIC ACID (277 patients)
CARVEDILOL (277 patients)
TEGRETOL (274 patients)
XIGRIS (270 patients)
CLINDAMYCIN (268 patients)
COZAAR (268 patients)
GLUCOPHAGE (267 patients)
IFOSFAMIDE (266 patients)
EFFEXOR (266 patients)
MIRALAX (264 patients)
Most common side effects for patients taking ALFENTANIL:
DRUG INTERACTION (75 patients)
DYSTONIA (56 patients)
MYOTONIA (54 patients)
RENAL IMPAIRMENT (42 patients)
SINUS TACHYCARDIA (34 patients)
AGITATION (32 patients)
BACK PAIN (28 patients)
TOXIC EPIDERMAL NECROLYSIS (28 patients)
INFECTION (26 patients)
CARDIAC ARREST (26 patients)
DRUG WITHDRAWAL SYNDROME (26 patients)
THERAPEUTIC AGENT TOXICITY (24 patients)
DRUG EFFECT DECREASED (24 patients)
BRADYCARDIA (23 patients)
TACHYCARDIA (19 patients)
MYOCLONUS (19 patients)
STARING (19 patients)
ANAPHYLACTIC SHOCK (18 patients)
HYPOTENSION (18 patients)
DRUG TOXICITY (18 patients)
MULTI-ORGAN FAILURE (17 patients)
VENTRICULAR FIBRILLATION (16 patients)
BRONCHOSPASM (16 patients)
DEATH (16 patients)
ALANINE AMINOTRANSFERASE INCREASED (15 patients)
OXYGEN SATURATION DECREASED (15 patients)
DRUG EXPOSURE DURING PREGNANCY (15 patients)
HEPATITIS (15 patients)
RESTLESSNESS (14 patients)
PANIC REACTION (14 patients)
LIVER FUNCTION TEST ABNORMAL (14 patients)
ABDOMINAL PAIN (13 patients)
WHITE BLOOD CELL COUNT INCREASED (13 patients)
TUBULOINTERSTITIAL NEPHRITIS (13 patients)
DRUG INEFFECTIVE (13 patients)
DRUG RASH WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS (13 patients)
ANAPHYLACTIC REACTION (12 patients)
HYPERHIDROSIS (12 patients)
NAUSEA (12 patients)
RENAL FAILURE ACUTE (12 patients)
GASTROINTESTINAL HAEMORRHAGE (12 patients)
OEDEMA PERIPHERAL (12 patients)
AGGRESSION (11 patients)
COMA (11 patients)
CYANOSIS (11 patients)
ESCHERICHIA INFECTION (11 patients)
SOMNOLENCE (11 patients)
HAEMOGLOBIN DECREASED (11 patients)
PLEURAL EFFUSION (10 patients)
BLOOD PHOSPHORUS INCREASED (10 patients)
HYPERVENTILATION (10 patients)
CONDITION AGGRAVATED (10 patients)
DISEASE PROGRESSION (10 patients)
HYPOXIA (10 patients)
FEELING ABNORMAL (10 patients)
PULMONARY OEDEMA (9 patients)
SPEECH DISORDER (9 patients)
MYALGIA (9 patients)
ATRIAL FIBRILLATION (9 patients)
PILOERECTION (9 patients)
CAESAREAN SECTION (9 patients)
SEROTONIN SYNDROME (9 patients)
CATATONIA (9 patients)
POST PROCEDURAL COMPLICATION (9 patients)
DYSPNOEA (9 patients)
MYDRIASIS (9 patients)
HEPATIC FAILURE (9 patients)
ACUTE RESPIRATORY DISTRESS SYNDROME (8 patients)
AKATHISIA (8 patients)
ANAESTHETIC COMPLICATION (8 patients)
LACERATION (8 patients)
BLOOD ALBUMIN DECREASED (8 patients)
BLOOD BILIRUBIN INCREASED (8 patients)
BLOOD CALCIUM INCREASED (8 patients)
BRAIN OEDEMA (8 patients)
PNEUMONIA (8 patients)
PUPILLARY REFLEX IMPAIRED (8 patients)
ELECTROCARDIOGRAM QT PROLONGED (8 patients)
RHABDOMYOLYSIS (8 patients)
BLISTER (7 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (7 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (7 patients)
HYPERSENSITIVITY (7 patients)
PYREXIA (7 patients)
C-REACTIVE PROTEIN INCREASED (7 patients)
PARAESTHESIA (7 patients)
VOMITING (7 patients)
PREMATURE RUPTURE OF MEMBRANES (7 patients)
SCLERODERMA (7 patients)
RENAL FAILURE (7 patients)
EXTENSOR PLANTAR RESPONSE (7 patients)
FATIGUE (7 patients)
HAEMATEMESIS (7 patients)
SLEEP DISORDER (7 patients)
PREMATURE LABOUR (7 patients)
ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED (6 patients)
AMNESIA (6 patients)
PEMPHIGOID (6 patients)
PROCEDURAL COMPLICATION (6 patients)
ASCITES INFECTION (6 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (6 patients)
HYPOCOAGULABLE STATE (6 patients)
BLOOD PRESSURE DECREASED (6 patients)
IDIOPATHIC THROMBOCYTOPENIC PURPURA (6 patients)
VENTRICULAR TACHYCARDIA (6 patients)
HYPERGLYCAEMIA (6 patients)
WOUND SECRETION (6 patients)
ENTEROCOCCAL INFECTION (6 patients)
MOVEMENT DISORDER (6 patients)
SEPSIS (6 patients)
NO THERAPEUTIC RESPONSE (6 patients)
GLASGOW COMA SCALE ABNORMAL (6 patients)
ABDOMINAL SEPSIS (5 patients)
HYPOTONIA (5 patients)
HYPERREFLEXIA (5 patients)
APHASIA (5 patients)
ASCITES (5 patients)
HYPERPARATHYROIDISM (5 patients)
HYPOKALAEMIA (5 patients)
CARDIO-RESPIRATORY ARREST (5 patients)
UNRESPONSIVE TO STIMULI (5 patients)
THROMBOCYTOPENIA (5 patients)
PROPOFOL INFUSION SYNDROME (5 patients)
ELECTROCARDIOGRAM ST SEGMENT DEPRESSION (5 patients)
SCREAMING (5 patients)
ISCHAEMIC STROKE (5 patients)
FALL (5 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (5 patients)
TREMOR (5 patients)
HEMIPLEGIA (5 patients)
SMALL INTESTINAL HAEMORRHAGE (5 patients)
NEUTROPENIA (4 patients)
ACCIDENTAL OVERDOSE (4 patients)
RESUSCITATION (4 patients)
AIRWAY COMPLICATION OF ANAESTHESIA (4 patients)
TRANSAMINASES INCREASED (4 patients)
ARRHYTHMIA (4 patients)
ARTHRALGIA (4 patients)
NO ADVERSE EVENT (4 patients)
BLOOD TRIGLYCERIDES INCREASED (4 patients)
INJURY (4 patients)
MATERNAL DRUGS AFFECTING FOETUS (4 patients)
RESPIRATORY DEPRESSION (4 patients)
MOTOR DYSFUNCTION (4 patients)
MUSCLE RIGIDITY (4 patients)
LABILE BLOOD PRESSURE (4 patients)
CELLULITIS (4 patients)
DELAYED RECOVERY FROM ANAESTHESIA (4 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (4 patients)
HYPERTENSION (4 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (4 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (4 patients)
PULMONARY EMBOLISM (4 patients)
ECTOPIC PREGNANCY (4 patients)
RASH ERYTHEMATOUS (4 patients)
MELAENA (4 patients)
FOETAL MALPRESENTATION (4 patients)
NEUTROPHILIA (4 patients)
GRAND MAL CONVULSION (4 patients)
SUBARACHNOID HAEMORRHAGE (4 patients)
OEDEMA (4 patients)
ABORTION INDUCED (3 patients)
ANHEDONIA (3 patients)
VARICOSE VEIN OPERATION (3 patients)
PAIN (3 patients)
ANXIETY (3 patients)
APALLIC SYNDROME (3 patients)
MICROSTOMIA (3 patients)
RESPIRATORY FAILURE (3 patients)
BLOOD CREATININE INCREASED (3 patients)
UNEVALUABLE EVENT (3 patients)
PANIC ATTACK (3 patients)
BLOOD POTASSIUM DECREASED (3 patients)
BONE DISORDER (3 patients)
BRAIN DEATH (3 patients)
CARDIAC DISORDER (3 patients)
METABOLIC ACIDOSIS (3 patients)
SKIN REACTION (3 patients)
PANCREATIC ABSCESS (3 patients)
CEREBRAL HAEMORRHAGE (3 patients)
CEREBRAL ISCHAEMIA (3 patients)
CEREBROVASCULAR ACCIDENT (3 patients)
CHOLESTASIS (3 patients)
ORGAN FAILURE (3 patients)
PANCREATITIS (3 patients)
CONVULSION (3 patients)
CYTOLYTIC HEPATITIS (3 patients)
TUMOUR LYSIS SYNDROME (3 patients)
PANCREATIC NECROSIS (3 patients)
DEHYDRATION (3 patients)
DEPRESSION (3 patients)
PROTHROMBIN TIME PROLONGED (3 patients)
DRUG HYPERSENSITIVITY (3 patients)
HYPOGLYCAEMIA NEONATAL (3 patients)
DYSPHASIA (3 patients)
DYSPHONIA (3 patients)
RENAL INJURY (3 patients)
LOCALISED OEDEMA (3 patients)
ELECTROMECHANICAL DISSOCIATION (3 patients)
RAYNAUD'S PHENOMENON (3 patients)
ERYTHEMA (3 patients)
FACE OEDEMA (3 patients)
FEAR (3 patients)
SEX CHROMOSOME ABNORMALITY (3 patients)
SKIN DISCOLOURATION (3 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (3 patients)
HAEMATOMA (3 patients)
HAEMODIALYSIS (3 patients)
THERAPY NON-RESPONDER (3 patients)
HEART RATE INCREASED (3 patients)

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