About this FactMed analysis covering adverse side effect reports of ALIZAPRIDE patients who developed AGRANULOCYTOSIS.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 2 individuals taking ALIZAPRIDE reported AGRANULOCYTOSIS to the FDA. A total of 102 ALIZAPRIDE drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between ALIZAPRIDE and AGRANULOCYTOSIS. In doing so, we compare ALIZAPRIDE with other drugs that cause AGRANULOCYTOSIS, to help you evaluate whether or not ALIZAPRIDE causes AGRANULOCYTOSIS. Likewise, this page shows the most highly-reported side effects of ALIZAPRIDE, so you can see if AGRANULOCYTOSIS ranks among ALIZAPRIDE's most well-known side effects.
Summary Statistics
Reports of ALIZAPRIDE causing AGRANULOCYTOSIS: 2
Reports of any side effect of ALIZAPRIDE : 102
Percentage of ALIZAPRIDE patients where AGRANULOCYTOSIS is a reported side effect: 1.9608%

FDA reports of any drug causing AGRANULOCYTOSIS : 5566
Average percentage for all medicated patients where AGRANULOCYTOSIS is reported as a complication: 0.0349%

Physician opinion on ALIZAPRIDE as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing ALIZAPRIDE:
DRUG USE FOR UNKNOWN INDICATION ( 14 patients )
NAUSEA ( 14 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 3 patients )
PREMEDICATION ( 2 patients )
VOMITING ( 2 patients )
ANTIEMETIC SUPPORTIVE CARE ( 2 patients )
PROPHYLAXIS ( 1 patients )
PROPHYLAXIS OF NAUSEA AND VOMITING ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with AGRANULOCYTOSIS:

CLOZAPINE (598 patients)
CLOZARIL (403 patients)
PREDNISOLONE (390 patients)
LASIX (335 patients)
ASPIRIN (304 patients)
CYCLOPHOSPHAMIDE (282 patients)
ACETAMINOPHEN (264 patients)
NEXIUM (255 patients)
OMEPRAZOLE (217 patients)
ALLOPURINOL (205 patients)
METHOTREXATE (204 patients)
SEROQUEL (202 patients)
BACTRIM (179 patients)
MABTHERA (176 patients)
PREDNISONE (174 patients)
NEUPOGEN (174 patients)
CELLCEPT (170 patients)
PLAVIX (167 patients)
MYCOPHENOLATE MOFETIL (161 patients)
VANCOMYCIN (158 patients)
PREDONINE (157 patients)
FUROSEMIDE (144 patients)
AUGMENTIN '125' (142 patients)
LANSOPRAZOLE (138 patients)
LORAZEPAM (136 patients)
ZOMETA (136 patients)
LYRICA (134 patients)
CLARITHROMYCIN (131 patients)
ROCEPHIN (129 patients)
VINCRISTINE (129 patients)
LEPONEX (127 patients)
RISPERDAL (127 patients)
LEVOTHYROXINE SODIUM (125 patients)
LOVENOX (118 patients)
FLAGYL (116 patients)
CARBOPLATIN (114 patients)
DOXORUBICIN HCL (113 patients)
ZYPREXA (108 patients)
TEGRETOL (105 patients)
ALDACTONE (103 patients)
FOSAMAX (101 patients)
DIFLUCAN (101 patients)
TAXOTERE (100 patients)
PROGRAF (100 patients)
XANAX (97 patients)
METHYLPREDNISOLONE (96 patients)
AREDIA (95 patients)
KEPPRA (95 patients)
PREVISCAN (93 patients)
CORTANCYL (92 patients)
CELEBREX (92 patients)
REMICADE (91 patients)
MIRTAZAPINE (90 patients)
FOLIC ACID (90 patients)
DIOVAN (90 patients)
TAKEPRON (89 patients)
RITUXIMAB (89 patients)
PREDNISONE TAB (88 patients)
DIGOXIN (87 patients)
LIPITOR (86 patients)
ETOPOSIDE (85 patients)
FLUOROURACIL (85 patients)
ENDOXAN (82 patients)
NEORAL (82 patients)
TRAMADOL HCL (81 patients)
PARACETAMOL (81 patients)
NEURONTIN (80 patients)
PANTOPRAZOLE (80 patients)
FLUCONAZOLE (80 patients)
DEPAKOTE (76 patients)
AMOXICILLIN (76 patients)
SOLU-MEDROL (76 patients)
CYCLOSPORINE (76 patients)
DECADRON (75 patients)
CORDARONE (75 patients)
IBUPROFEN (75 patients)
CLONAZEPAM (75 patients)
DEXAMETHASONE (74 patients)
OLANZAPINE (74 patients)
PANTOPRAZOLE SODIUM (74 patients)
POTASSIUM CHLORIDE (73 patients)
SIMVASTATIN (73 patients)
ENBREL (72 patients)
HALDOL (72 patients)
CYTARABINE (72 patients)
WARFARIN SODIUM (71 patients)
CISPLATIN (70 patients)
RITUXAN (70 patients)
CLAFORAN (69 patients)
VOLTAREN (69 patients)
NORVASC (68 patients)
FAMOTIDINE (68 patients)
ARIMIDEX (68 patients)
TAZOCILLINE (68 patients)
CIPROFLOXACIN (67 patients)
RAMIPRIL (66 patients)
TACROLIMUS (66 patients)
ATENOLOL (66 patients)
LEVOFLOXACIN (65 patients)
CITALOPRAM HYDROBROMIDE (65 patients)
ADRIAMYCIN PFS (64 patients)
LOXONIN (64 patients)
GLEEVEC (63 patients)
CRESTOR (63 patients)
AMLODIPINE BESYLATE (62 patients)
BISOPROLOL FUMARATE (62 patients)
AMPHOTERICIN B (62 patients)
ZOFRAN (62 patients)
MUCOSTA (61 patients)
COUMADIN (61 patients)
DIAZEPAM (61 patients)
AMLODIPINE (59 patients)
PROTONIX (59 patients)
KARDEGIC (59 patients)
ATIVAN (59 patients)
AMBIEN (58 patients)
CEFTRIAXONE (57 patients)
MORPHINE (56 patients)
MEROPENEM (56 patients)
CIPROFLOXACIN HCL (56 patients)
GENTAMICIN (55 patients)
ACTONEL (55 patients)
ATARAX (55 patients)
METFORMIN HCL (55 patients)
SULFASALAZINE (55 patients)
ABILIFY (54 patients)
IMOVANE (54 patients)
ZOLPIDEM TARTRATE (53 patients)
NAVELBINE (53 patients)
OFLOCET (53 patients)
ARANESP (52 patients)
ADALAT (52 patients)
DEPAKENE (52 patients)
VALSARTAN (52 patients)
TENORMIN (52 patients)
GABAPENTIN (51 patients)
NOVALGIN (51 patients)
ENALAPRIL MALEATE (50 patients)
AVELOX (50 patients)
VALTREX (49 patients)
SYNTHROID (49 patients)
FELODIPINE (49 patients)
ACYCLOVIR (49 patients)
HALOPERIDOL (49 patients)
DURAGESIC-100 (49 patients)
PEPCID (48 patients)
RABEPRAZOLE SODIUM (48 patients)
INIPOMP (48 patients)
VALPROATE SODIUM (48 patients)
ALPRAZOLAM (48 patients)
RISPERIDONE (48 patients)
AMARYL (47 patients)
ZOLOFT (47 patients)
VALGANCICLOVIR (47 patients)
LAMOTRIGINE (47 patients)
NEXAVAR (46 patients)
FLUDARABINE PHOSPHATE (46 patients)
AUGMENTIN (46 patients)
PRIMAXIN (45 patients)
MAGNESIUM OXIDE (45 patients)
MOPRAL (45 patients)
LITHIUM CARBONATE (45 patients)
DUPHALAC (45 patients)
CARVEDILOL (45 patients)
AZULFIDINE (45 patients)
PIPERACILLIN AND TAZOBACTAM (44 patients)
TAGAMET (44 patients)
ROVALCYTE (44 patients)
ATORVASTATIN CALCIUM (43 patients)
AROMASIN (42 patients)
ZELITREX (42 patients)
ENOXAPARIN SODIUM (42 patients)
ARTIST (42 patients)
TERCIAN (42 patients)
RIFAMPICIN (42 patients)
OFLOXACIN (41 patients)
BACTRIM DS (41 patients)
TAMIFLU (41 patients)
SELBEX (41 patients)
LAMICTAL (41 patients)
ZOLPIDEM (40 patients)
KYTRIL (40 patients)
SPIRONOLACTONE (40 patients)
METRONIDAZOLE (40 patients)
TARGOCID (40 patients)
ARAVA (40 patients)
FAZACLO ODT (40 patients)
VINCRISTINE SULFATE (39 patients)
NEULASTA (39 patients)
FERROUS SULFATE TAB (39 patients)
INSULIN (39 patients)
FORLAX (39 patients)
DOLIPRANE (39 patients)
SIGMART (39 patients)
OXYCONTIN (39 patients)
ZYLORIC (38 patients)
CHEMOTHERAPEUTICS,OTHER (38 patients)
RANITIDINE (38 patients)
BENADRYL (38 patients)
MYFORTIC (38 patients)
TAXOL (38 patients)
IFOSFAMIDE (38 patients)
TICLOPIDINE HCL (38 patients)
TAMOXIFEN CITRATE (37 patients)
ASPEGIC 1000 (37 patients)
HUMIRA (37 patients)
TRUVADA (37 patients)
GEMZAR (37 patients)
TAHOR (37 patients)
PLETAL (37 patients)
Most common side effects for patients taking ALIZAPRIDE:
DIARRHOEA (16 patients)
PYREXIA (16 patients)
VOMITING (10 patients)
FATIGUE (9 patients)
HYPOKALAEMIA (9 patients)
DEHYDRATION (8 patients)
NAUSEA (7 patients)
ANAEMIA (6 patients)
ASTHENIA (6 patients)
BRONCHOPNEUMONIA (6 patients)
DRUG INTERACTION (6 patients)
DYSPNOEA (6 patients)
HYPOTENSION (6 patients)
PNEUMONIA (6 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (5 patients)
HAEMORRHAGE (5 patients)
HYPOMAGNESAEMIA (5 patients)
HYPOPHOSPHATAEMIA (5 patients)
JAUNDICE (5 patients)
RESPIRATORY FAILURE (5 patients)
SOMNOLENCE (5 patients)
TACHYCARDIA (5 patients)
ABDOMINAL PAIN (4 patients)
ADVERSE DRUG REACTION (4 patients)
FALL (4 patients)
HAEMODIALYSIS (4 patients)
HAEMOGLOBIN DECREASED (4 patients)
INTESTINAL OBSTRUCTION (4 patients)
MALAISE (4 patients)
SLEEP APNOEA SYNDROME (4 patients)
SUPRAVENTRICULAR TACHYCARDIA (4 patients)
THROMBOCYTHAEMIA (4 patients)
THROMBOCYTOPENIA (4 patients)
WHITE BLOOD CELL COUNT DECREASED (4 patients)
ACUTE RESPIRATORY DISTRESS SYNDROME (3 patients)
BACTERIAL SEPSIS (3 patients)
BLOOD BILIRUBIN INCREASED (3 patients)
BLOOD CREATININE INCREASED (3 patients)
DECREASED APPETITE (3 patients)
DERMATITIS EXFOLIATIVE (3 patients)
DEVICE DISLOCATION (3 patients)
ENTERITIS (3 patients)
FEBRILE NEUTROPENIA (3 patients)
FIBRIN D DIMER INCREASED (3 patients)
FUSOBACTERIUM INFECTION (3 patients)
HAEMOPTYSIS (3 patients)
HYPOXIA (3 patients)
ILEUS (3 patients)
LEUKAEMIA RECURRENT (3 patients)
MUCOSAL INFLAMMATION (3 patients)
NEUROTOXICITY (3 patients)
NEUTROPENIA (3 patients)
OVERDOSE (3 patients)
PRESYNCOPE (3 patients)
PROTEUS INFECTION (3 patients)
RASH (3 patients)
RENAL FAILURE ACUTE (3 patients)
SEPTIC SHOCK (3 patients)
SUPERINFECTION (3 patients)
TONGUE DISORDER (3 patients)
ACUTE PULMONARY OEDEMA (2 patients)
AGRANULOCYTOSIS (2 patients)
ATRIAL FIBRILLATION (2 patients)
BLOOD FIBRINOGEN INCREASED (2 patients)
BLOOD GLUCOSE INCREASED (2 patients)
BONE MARROW DEPRESSION (2 patients)
BONE MARROW FAILURE (2 patients)
BRONCHOPULMONARY ASPERGILLOSIS (2 patients)
C-REACTIVE PROTEIN INCREASED (2 patients)
CHILLS (2 patients)
COLITIS ISCHAEMIC (2 patients)
CONSTIPATION (2 patients)
CONVULSION (2 patients)
CORONARY ARTERY DISEASE (2 patients)
DEAFNESS (2 patients)
DIZZINESS (2 patients)
DRUG ADMINISTRATION ERROR (2 patients)
DYSPHAGIA (2 patients)
DYSURIA (2 patients)
EJECTION FRACTION DECREASED (2 patients)
ERYSIPELAS (2 patients)
FACIAL PALSY (2 patients)
FEBRILE BONE MARROW APLASIA (2 patients)
FLATULENCE (2 patients)
GASTROENTERITIS (2 patients)
HAEMATOCRIT DECREASED (2 patients)
HYPERSENSITIVITY (2 patients)
INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION (2 patients)
INFECTION (2 patients)
KLEBSIELLA SEPSIS (2 patients)
LEUKOPENIA (2 patients)
LYMPHANGITIS (2 patients)
LYMPHOCYTE COUNT INCREASED (2 patients)
NERVOUS SYSTEM DISORDER (2 patients)
NEUTROPHIL COUNT DECREASED (2 patients)
OEDEMA MUCOSAL (2 patients)
OTITIS MEDIA (2 patients)
PANCYTOPENIA (2 patients)
PARTIAL SEIZURES (2 patients)
PLATELET COUNT DECREASED (2 patients)
PULMONARY EMBOLISM (2 patients)
RED BLOOD CELL COUNT DECREASED (2 patients)
RENAL FAILURE (2 patients)
RHINORRHOEA (2 patients)
SHOCK (2 patients)
STREPTOCOCCAL SEPSIS (2 patients)
SUDDEN CARDIAC DEATH (2 patients)
URTICARIA (2 patients)
ACCIDENTAL OVERDOSE (1 patients)
ACUTE GRAFT VERSUS HOST DISEASE IN INTESTINE (1 patients)
ACUTE GRAFT VERSUS HOST DISEASE IN SKIN (1 patients)
AGITATION (1 patients)
ALVEOLITIS (1 patients)
ANOREXIA (1 patients)
ANXIETY (1 patients)
APHASIA (1 patients)
APHTHOUS STOMATITIS (1 patients)
ARACHNOIDITIS (1 patients)
BLOOD CULTURE POSITIVE (1 patients)
CALCULUS URINARY (1 patients)
CANDIDA SEPSIS (1 patients)
CANDIDIASIS (1 patients)
CARDIO-RESPIRATORY ARREST (1 patients)
CENTRAL NERVOUS SYSTEM LEUKAEMIA (1 patients)
CEREBRAL HAEMORRHAGE (1 patients)
CHEST PAIN (1 patients)
COLITIS (1 patients)
CONFUSIONAL STATE (1 patients)
COUGH (1 patients)
CYANOSIS (1 patients)
DIARRHOEA INFECTIOUS (1 patients)
DISEASE PROGRESSION (1 patients)
DISLOCATION OF VERTEBRA (1 patients)
DOCUMENTED HYPERSENSITIVITY TO ADMINISTERED DRUG (1 patients)
DRUG HYPERSENSITIVITY (1 patients)
DRUG TOXICITY (1 patients)
DRY SKIN (1 patients)
ENCEPHALOPATHY (1 patients)
EPILEPSY (1 patients)
ERYTHEMA (1 patients)
FLUSHING (1 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (1 patients)
GENERAL PHYSICAL CONDITION ABNORMAL (1 patients)
GRAFT VERSUS HOST DISEASE (1 patients)
HAEMATURIA (1 patients)
HEADACHE (1 patients)
HYPERBILIRUBINAEMIA (1 patients)
HYPERTENSIVE CRISIS (1 patients)
HYPOACUSIS (1 patients)
HYPOAESTHESIA (1 patients)
HYPOCALCAEMIA (1 patients)
HYPOMANIA (1 patients)
HYPOVOLAEMIC SHOCK (1 patients)
KLEBSIELLA INFECTION (1 patients)
LACTOSE INTOLERANCE (1 patients)
LEUKAEMIA PLASMACYTIC (1 patients)
METASTATIC NEOPLASM (1 patients)
MULTI-ORGAN FAILURE (1 patients)
MULTIPLE MYELOMA (1 patients)
MUSCULAR WEAKNESS (1 patients)
MYALGIA (1 patients)
MYOGLOBIN BLOOD INCREASED (1 patients)
NEOPLASM (1 patients)
NEURALGIA (1 patients)
OEDEMA (1 patients)
OEDEMA PERIPHERAL (1 patients)
PAIN (1 patients)
PARESIS (1 patients)
PNEUMONIA KLEBSIELLA (1 patients)
PNEUMONITIS (1 patients)
PRODUCTIVE COUGH (1 patients)
PRURITUS (1 patients)
PULMONARY ALVEOLAR HAEMORRHAGE (1 patients)
PULMONARY HYPERTENSION (1 patients)
RADIUS FRACTURE (1 patients)
RASH GENERALISED (1 patients)
RASH MACULAR (1 patients)
RASH MACULO-PAPULAR (1 patients)
RENAL COLIC (1 patients)
RESPIRATORY DISTRESS (1 patients)
RIGHT VENTRICULAR DYSFUNCTION (1 patients)
SEPSIS (1 patients)
SKIN LESION (1 patients)
SPUTUM PURULENT (1 patients)
STAPHYLOCOCCAL BACTERAEMIA (1 patients)
STEM CELL TRANSPLANT (1 patients)
STOMATITIS (1 patients)
THROMBOSIS (1 patients)
THROMBOTIC MICROANGIOPATHY (1 patients)
TOXICITY TO VARIOUS AGENTS (1 patients)
ULNA FRACTURE (1 patients)
WEIGHT DECREASED (1 patients)

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