About this FactMed analysis covering adverse side effect reports of ALMARL patients who developed BRADYCARDIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 4 individuals taking ALMARL reported BRADYCARDIA to the FDA. A total of 227 ALMARL drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between ALMARL and BRADYCARDIA. In doing so, we compare ALMARL with other drugs that cause BRADYCARDIA, to help you evaluate whether or not ALMARL causes BRADYCARDIA. Likewise, this page shows the most highly-reported side effects of ALMARL, so you can see if BRADYCARDIA ranks among ALMARL's most well-known side effects.
Summary Statistics
Reports of ALMARL causing BRADYCARDIA: 4
Reports of any side effect of ALMARL : 227
Percentage of ALMARL patients where BRADYCARDIA is a reported side effect: 1.7621%

FDA reports of any drug causing BRADYCARDIA : 18843
Average percentage for all medicated patients where BRADYCARDIA is reported as a complication: 0.1181%

Physician opinion on ALMARL as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing ALMARL:
HYPERTENSION ( 76 patients )
PARKINSON'S DISEASE ( 8 patients )
ESSENTIAL TREMOR ( 6 patients )
ATRIAL FIBRILLATION ( 4 patients )
SCHIZOPHRENIA ( 2 patients )
TREMOR ( 2 patients )
ANGINA PECTORIS ( 2 patients )
DRUG USE FOR UNKNOWN INDICATION ( 2 patients )
PALPITATIONS ( 2 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 2 patients )
TACHYCARDIA ( 2 patients )
HYPERTROPHY ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with BRADYCARDIA:

ASPIRIN (2408 patients)
DIGOXIN (2012 patients)
VIOXX (1475 patients)
LASIX (1359 patients)
HEPARIN SODIUM INJECTION (1266 patients)
ATENOLOL (1166 patients)
FUROSEMIDE (1105 patients)
LISINOPRIL (911 patients)
METOPROLOL TARTRATE (781 patients)
PLAVIX (730 patients)
COUMADIN (690 patients)
FOSAMAX (669 patients)
SIMVASTATIN (658 patients)
LIPITOR (658 patients)
OMEPRAZOLE (644 patients)
ACETAMINOPHEN (634 patients)
WARFARIN SODIUM (622 patients)
POTASSIUM CHLORIDE (603 patients)
ALLOPURINOL (580 patients)
HYDROCHLOROTHIAZIDE (565 patients)
NORVASC (558 patients)
AMLODIPINE (521 patients)
LEVOTHYROXINE SODIUM (516 patients)
CARVEDILOL (505 patients)
ALDACTONE (465 patients)
CORDARONE (461 patients)
NITROGLYCERIN (458 patients)
NEXIUM (450 patients)
ARICEPT (429 patients)
LYRICA (406 patients)
AMIODARONE HCL (405 patients)
SYNTHROID (402 patients)
METOPROLOL (400 patients)
TOPROL-XL (400 patients)
LORAZEPAM (400 patients)
SPIRONOLACTONE (396 patients)
METFORMIN HCL (394 patients)
BISOPROLOL FUMARATE (389 patients)
ZOCOR (380 patients)
COREG (377 patients)
RAMIPRIL (372 patients)
ALBUTEROL (369 patients)
DILTIAZEM (365 patients)
DIOVAN (358 patients)
VERAPAMIL (357 patients)
PROPOFOL (353 patients)
PROTONIX (351 patients)
INSULIN (350 patients)
PREDNISONE (338 patients)
ENALAPRIL MALEATE (324 patients)
FENTANYL (321 patients)
SEROQUEL (319 patients)
HEPARIN (313 patients)
METOPROLOL SUCCINATE (309 patients)
MORPHINE (308 patients)
RISPERDAL (305 patients)
FOLIC ACID (303 patients)
PAXIL (302 patients)
ALPRAZOLAM (301 patients)
LOPRESSOR (299 patients)
NEURONTIN (294 patients)
AMBIEN (293 patients)
PRILOSEC (291 patients)
XANAX (288 patients)
LEVAQUIN (284 patients)
CLONIDINE (275 patients)
RANITIDINE (273 patients)
HEPARIN SODIUM (266 patients)
TENORMIN (261 patients)
IBUPROFEN (253 patients)
CLONAZEPAM (248 patients)
ALTACE (246 patients)
EXELON (246 patients)
ATORVASTATIN CALCIUM (241 patients)
LOVENOX (240 patients)
CELEBREX (234 patients)
SANDOSTATIN LAR (234 patients)
CRESTOR (229 patients)
GILENYA (227 patients)
CITALOPRAM HYDROBROMIDE (224 patients)
ZOLOFT (221 patients)
PREVACID (220 patients)
LANTUS (220 patients)
GABAPENTIN (216 patients)
PROPRANOLOL (214 patients)
DILTIAZEM HCL (212 patients)
PREDNISOLONE (212 patients)
ATIVAN (211 patients)
GLYBURIDE (210 patients)
CARDIZEM (208 patients)
COZAAR (207 patients)
ZOMETA (202 patients)
ZYPREXA (202 patients)
LANOXIN (198 patients)
DIAZEPAM (196 patients)
SEVOFLURANE (196 patients)
PRAVASTATIN (196 patients)
LANSOPRAZOLE (194 patients)
REMICADE (192 patients)
VITAMIN D (191 patients)
NIFEDIPINE (190 patients)
FERROUS SULFATE TAB (189 patients)
GLUCOPHAGE (189 patients)
ACYCLOVIR (185 patients)
FAMOTIDINE (184 patients)
METHOTREXATE (184 patients)
DEXAMETHASONE (183 patients)
LIDOCAINE (183 patients)
BACTRIM (183 patients)
ATROPINE (182 patients)
TRAMADOL HCL (182 patients)
TEGRETOL (180 patients)
FLUCONAZOLE (179 patients)
OXYGEN (179 patients)
REVLIMID (179 patients)
LITHIUM CARBONATE (177 patients)
AVANDIA (176 patients)
PANTOPRAZOLE (176 patients)
LEXAPRO (175 patients)
BACLOFEN (175 patients)
FENTANYL CITRATE (175 patients)
DILTIAZEM HYDROCHLORIDE (174 patients)
AMLODIPINE BESYLATE (174 patients)
KLOR-CON (173 patients)
ZOFRAN (173 patients)
CLOPIDOGREL (173 patients)
CIPROFLOXACIN (172 patients)
TEMAZEPAM (171 patients)
AMIODARONE (171 patients)
CALCIUM (171 patients)
ACETYLSALICYLIC ACID SRT (170 patients)
KEPPRA (169 patients)
AMITRIPTYLINE HCL (169 patients)
VANCOMYCIN (168 patients)
THALOMID (168 patients)
MULTI-VITAMIN (167 patients)
ISOSORBIDE MONONITRATE (166 patients)
ZITHROMAX (163 patients)
ATACAND (163 patients)
MULTI-VITAMINS (162 patients)
SOLU-MEDROL (162 patients)
TYLENOL (CAPLET) (161 patients)
PERCOCET (158 patients)
TORSEMIDE (158 patients)
VICODIN (158 patients)
MIDAZOLAM HCL (157 patients)
PREDNISONE TAB (156 patients)
TYLENOL (156 patients)
ADVAIR DISKUS 100/50 (154 patients)
ACTOS (151 patients)
ONDANSETRON (150 patients)
METFORMIN (150 patients)
AMOXICILLIN (149 patients)
PREMARIN (149 patients)
SPIRIVA (147 patients)
CYCLOPHOSPHAMIDE (146 patients)
MULTAQ (146 patients)
PRAVACHOL (145 patients)
PROZAC (145 patients)
LORTAB (144 patients)
HEPARIN SODIUM 5,000 UNITS IN DEXTROSE 5% (144 patients)
EPINEPHRINE (144 patients)
KALETRA (144 patients)
PANTOPRAZOLE SODIUM (143 patients)
SOTALOL HCL (143 patients)
BISOPROLOL (143 patients)
GLIPIZIDE (142 patients)
PREVISCAN (142 patients)
VECURONIUM BROMIDE (142 patients)
SINGULAIR (140 patients)
ATROVENT (140 patients)
MORPHINE SULFATE (139 patients)
PARACETAMOL (138 patients)
ZYRTEC (137 patients)
ZANTAC (137 patients)
ISOSORBIDE DINITRATE (137 patients)
FLOMAX (136 patients)
ALLEGRA (136 patients)
CELEXA (136 patients)
DIPRIVAN (135 patients)
AMARYL (134 patients)
CAPTOPRIL (133 patients)
CEPHALEXIN (133 patients)
FELODIPINE (132 patients)
COLACE (132 patients)
METHYLPREDNISOLONE (131 patients)
ALENDRONATE SODIUM (131 patients)
LACTULOSE (130 patients)
CALCIUM CARBONATE (130 patients)
ZESTRIL (130 patients)
WARFARIN (130 patients)
CYMBALTA (130 patients)
IMDUR (128 patients)
FISH OIL (127 patients)
DOXAZOSIN MESYLATE (127 patients)
ATORVASTATIN (125 patients)
METOCLOPRAMIDE (125 patients)
MAGNESIUM OXIDE (125 patients)
HEPARIN SODIUM 1,000 UNITS AND SODIUM CHLORIDE 0.9% (125 patients)
OXYCONTIN (123 patients)
AVELOX (122 patients)
MICARDIS (122 patients)
FLUOXETINE (121 patients)
[THERAPY UNSPECIFIED] (119 patients)
SODIUM CHLORIDE (119 patients)
ZOLPIDEM (119 patients)
CLARITHROMYCIN (118 patients)
OLANZAPINE (118 patients)
ZETIA (117 patients)
TRAZODONE HCL (117 patients)
Most common side effects for patients taking ALMARL:
DEPRESSED LEVEL OF CONSCIOUSNESS (20 patients)
HALLUCINATION (15 patients)
FALL (13 patients)
HYPOGLYCAEMIA (13 patients)
PYREXIA (12 patients)
TREMOR (12 patients)
DIARRHOEA (11 patients)
HEPATIC FUNCTION ABNORMAL (11 patients)
PNEUMONIA (10 patients)
DYSARTHRIA (10 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (9 patients)
RENAL FAILURE ACUTE (9 patients)
LIVER DISORDER (9 patients)
CEREBRAL INFARCTION (8 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (8 patients)
DRUG INEFFECTIVE (8 patients)
RENAL IMPAIRMENT (8 patients)
HYPONATRAEMIA (8 patients)
INTERSTITIAL LUNG DISEASE (8 patients)
JAUNDICE (8 patients)
OEDEMA PERIPHERAL (8 patients)
CONDITION AGGRAVATED (7 patients)
DELIRIUM (7 patients)
DYSPHAGIA (7 patients)
DYSPNOEA (7 patients)
HYPOAESTHESIA (7 patients)
RHABDOMYOLYSIS (7 patients)
VOMITING (6 patients)
DELUSION (6 patients)
RESPIRATORY FAILURE (6 patients)
DYSKINESIA (6 patients)
SOMNOLENCE (6 patients)
HEPATIC NEOPLASM MALIGNANT (6 patients)
HYPERGLYCAEMIA (6 patients)
HYPOKALAEMIA (6 patients)
MOVEMENT DISORDER (6 patients)
MUSCULAR WEAKNESS (6 patients)
WHITE BLOOD CELL COUNT INCREASED (5 patients)
BLADDER CANCER (5 patients)
BLOOD ANTIDIURETIC HORMONE INCREASED (5 patients)
RESTLESSNESS (5 patients)
BLOOD OSMOLARITY DECREASED (5 patients)
PLEURAL EFFUSION (5 patients)
C-REACTIVE PROTEIN INCREASED (5 patients)
CONVULSION (5 patients)
RENAL DISORDER (5 patients)
VITH NERVE PARALYSIS (5 patients)
INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION (5 patients)
INTESTINAL OBSTRUCTION (5 patients)
SEPSIS (5 patients)
ROAD TRAFFIC ACCIDENT (5 patients)
MUSCULOSKELETAL PAIN (5 patients)
NAUSEA (5 patients)
ANOREXIA (4 patients)
ATELECTASIS (4 patients)
ATRIAL FIBRILLATION (4 patients)
ATRIOVENTRICULAR BLOCK (4 patients)
BLOOD CREATININE INCREASED (4 patients)
BRADYCARDIA (4 patients)
CARDIAC FAILURE (4 patients)
CONSTIPATION (4 patients)
DECREASED APPETITE (4 patients)
DEHYDRATION (4 patients)
DIZZINESS (4 patients)
PLATELET COUNT DECREASED (4 patients)
PAIN (4 patients)
HYPERTENSION (4 patients)
HYPOTHYROIDISM (4 patients)
ILEUS (4 patients)
METABOLIC ACIDOSIS (4 patients)
SMALL INTESTINE CARCINOMA (4 patients)
URINE OSMOLARITY INCREASED (4 patients)
ABASIA (3 patients)
AGGRESSION (3 patients)
PRURITUS (3 patients)
ANAEMIA (3 patients)
PULMONARY ALVEOLAR HAEMORRHAGE (3 patients)
WHITE BLOOD CELL COUNT DECREASED (3 patients)
ASTHMA (3 patients)
BLOOD BILIRUBIN INCREASED (3 patients)
RENAL FAILURE (3 patients)
BLOOD PRESSURE DECREASED (3 patients)
BLOOD PRESSURE INCREASED (3 patients)
VASCULITIS (3 patients)
CAROTID ARTERY STENOSIS (3 patients)
THERAPEUTIC AGENT TOXICITY (3 patients)
CHILLS (3 patients)
CHROMATURIA (3 patients)
PETECHIAE (3 patients)
CHRONIC LYMPHOCYTIC LEUKAEMIA (3 patients)
PORIOMANIA (3 patients)
RENAL ARTERY STENOSIS (3 patients)
PANCYTOPENIA (3 patients)
DRUG ERUPTION (3 patients)
SUDDEN ONSET OF SLEEP (3 patients)
DRUG WITHDRAWAL SYNDROME (3 patients)
VERTIGO (3 patients)
EPILEPSY (3 patients)
FACE OEDEMA (3 patients)
VOLVULUS (3 patients)
GENERALISED OEDEMA (3 patients)
GINGIVAL BLEEDING (3 patients)
HAEMORRHAGE SUBCUTANEOUS (3 patients)
HALLUCINATION, VISUAL (3 patients)
PSYCHIATRIC SYMPTOM (3 patients)
HEART RATE DECREASED (3 patients)
HELICOBACTER TEST POSITIVE (3 patients)
HEPATITIS FULMINANT (3 patients)
HYPERKALAEMIA (3 patients)
HYPOTENSION (3 patients)
IDIOPATHIC THROMBOCYTOPENIC PURPURA (3 patients)
LOSS OF CONSCIOUSNESS (3 patients)
SENSORY DISTURBANCE (3 patients)
LYMPHOMA (3 patients)
MALAISE (3 patients)
MARKEDLY REDUCED DIETARY INTAKE (3 patients)
RENAL TUBULAR DISORDER (3 patients)
NEOPLASM MALIGNANT (3 patients)
SINUS ARREST (3 patients)
ABDOMINAL DISCOMFORT (2 patients)
ABDOMINAL PAIN (2 patients)
ACUTE MYELOID LEUKAEMIA (2 patients)
STOMACH MASS (2 patients)
PERSONALITY CHANGE (2 patients)
AGITATION (2 patients)
ALTERED STATE OF CONSCIOUSNESS (2 patients)
ANAPHYLACTOID REACTION (2 patients)
ANGER (2 patients)
PRODUCTIVE COUGH (2 patients)
RENAL CYST (2 patients)
APHASIA (2 patients)
ASTHENIA (2 patients)
ATRIOVENTRICULAR BLOCK COMPLETE (2 patients)
THIRST (2 patients)
PROSTATE CANCER (2 patients)
BLOOD AMYLASE INCREASED (2 patients)
BLOOD UREA INCREASED (2 patients)
BODY TEMPERATURE INCREASED (2 patients)
SPEECH DISORDER (2 patients)
TUMOUR LYSIS SYNDROME (2 patients)
CEREBRAL HAEMORRHAGE (2 patients)
CHEST X-RAY ABNORMAL (2 patients)
COLON CANCER (2 patients)
COMA HEPATIC (2 patients)
COMPLETED SUICIDE (2 patients)
CONTUSION (2 patients)
PERFORMANCE STATUS DECREASED (2 patients)
DEFAECATION URGENCY (2 patients)
DEMENTIA ALZHEIMER'S TYPE (2 patients)
RASH PRURITIC (2 patients)
DIABETIC KETOACIDOSIS (2 patients)
DRUG INTERACTION (2 patients)
DRUG LEVEL INCREASED (2 patients)
DYSPEPSIA (2 patients)
DYSSTASIA (2 patients)
ELECTROCARDIOGRAM QT PROLONGED (2 patients)
STEVENS-JOHNSON SYNDROME (2 patients)
EPULIS (2 patients)
EXTRAOCULAR MUSCLE PARESIS (2 patients)
FACIAL PARESIS (2 patients)
FEAR (2 patients)
FEBRILE NEUTROPENIA (2 patients)
FEMORAL NECK FRACTURE (2 patients)
FOOT FRACTURE (2 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (2 patients)
GANGRENE (2 patients)
GASTRIC ULCER HAEMORRHAGE (2 patients)
GINGIVAL HYPERTROPHY (2 patients)
GLOSSOPTOSIS (2 patients)
PLEURISY (2 patients)
PHRENIC NERVE PARALYSIS (2 patients)
HAEMATEMESIS (2 patients)
HAEMATURIA (2 patients)
HAEMOGLOBIN DECREASED (2 patients)
POLLAKIURIA (2 patients)
ORAL INTAKE REDUCED (2 patients)
HEPATIC CYST (2 patients)
HEPATIC ENCEPHALOPATHY (2 patients)
HEPATITIS (2 patients)
HYPERREFLEXIA (2 patients)
HYPERTONIA (2 patients)
HYPERURICAEMIA (2 patients)
RASH PAPULAR (2 patients)
INITIAL INSOMNIA (2 patients)
RETINAL OEDEMA (2 patients)
INTESTINAL FUNCTIONAL DISORDER (2 patients)
RESPIRATION ABNORMAL (2 patients)
IRRITABILITY (2 patients)
RIB FRACTURE (2 patients)
LEG AMPUTATION (2 patients)
LYMPHADENOPATHY (2 patients)
METABOLIC ALKALOSIS (2 patients)
ORAL HERPES (2 patients)
TAKAYASU'S ARTERITIS (2 patients)
MOUTH HAEMORRHAGE (2 patients)
UNRESPONSIVE TO STIMULI (2 patients)
TOXIC SKIN ERUPTION (2 patients)
NEPHROLITHIASIS (2 patients)
SUICIDE ATTEMPT (2 patients)
VENTRICULAR FIBRILLATION (2 patients)
NEUTROPHIL COUNT DECREASED (2 patients)
UPPER RESPIRATORY TRACT INFECTION (2 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (2 patients)
SHOCK HAEMORRHAGIC (2 patients)
ABDOMEN CRUSHING (1 patients)
CARDIAC FAILURE CONGESTIVE (1 patients)
EOSINOPHILIC PNEUMONIA ACUTE (1 patients)
ESSENTIAL TREMOR (1 patients)
WRONG TECHNIQUE IN DRUG USAGE PROCESS (1 patients)
FUNGAL INFECTION (1 patients)

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