About this FactMed analysis covering adverse side effect reports of ALMARL patients who developed HYPERTONIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 2 individuals taking ALMARL reported HYPERTONIA to the FDA. A total of 227 ALMARL drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between ALMARL and HYPERTONIA. In doing so, we compare ALMARL with other drugs that cause HYPERTONIA, to help you evaluate whether or not ALMARL causes HYPERTONIA. Likewise, this page shows the most highly-reported side effects of ALMARL, so you can see if HYPERTONIA ranks among ALMARL's most well-known side effects.
Summary Statistics
Reports of ALMARL causing HYPERTONIA: 2
Reports of any side effect of ALMARL : 227
Percentage of ALMARL patients where HYPERTONIA is a reported side effect: 0.8811%

FDA reports of any drug causing HYPERTONIA : 3789
Average percentage for all medicated patients where HYPERTONIA is reported as a complication: 0.0237%

Physician opinion on ALMARL as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing ALMARL:
HYPERTENSION ( 76 patients )
PARKINSON'S DISEASE ( 8 patients )
ESSENTIAL TREMOR ( 6 patients )
ATRIAL FIBRILLATION ( 4 patients )
SCHIZOPHRENIA ( 2 patients )
TREMOR ( 2 patients )
ANGINA PECTORIS ( 2 patients )
DRUG USE FOR UNKNOWN INDICATION ( 2 patients )
PALPITATIONS ( 2 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 2 patients )
TACHYCARDIA ( 2 patients )
HYPERTROPHY ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with HYPERTONIA:

LIORESAL (2098 patients)
ORAL BACLOFEN (97 patients)
BACLOFEN (77 patients)
RISPERDAL (75 patients)
MIRTAZAPINE (71 patients)
ASPIRIN (70 patients)
PAROXETINE HCL (63 patients)
RETROVIR (61 patients)
EFFEXOR XR (60 patients)
LAMICTAL (56 patients)
LEVOTHYROXINE SODIUM (55 patients)
FLUOXETINE (54 patients)
CITALOPRAM HYDROBROMIDE (53 patients)
LORAZEPAM (50 patients)
RISPERIDONE (49 patients)
OMEPRAZOLE (48 patients)
DIAZEPAM (45 patients)
CLONAZEPAM (44 patients)
HALDOL (43 patients)
XANAX (42 patients)
NEXIUM (41 patients)
TRAMADOL HCL (39 patients)
ZIDOVUDINE (39 patients)
ALPRAZOLAM (39 patients)
HALOPERIDOL (38 patients)
ACETAMINOPHEN (38 patients)
VALPROATE SODIUM (38 patients)
DEPAKENE (38 patients)
LITHIUM CARBONATE (37 patients)
PAXIL (36 patients)
REBIF (35 patients)
SEROQUEL (34 patients)
LAMIVUDINE (34 patients)
PROZAC (34 patients)
VALIUM (34 patients)
LAMOTRIGINE (32 patients)
ZOLOFT (32 patients)
MORPHINE (31 patients)
DEROXAT (30 patients)
LYRICA (30 patients)
PREDNISOLONE (30 patients)
KEPPRA (30 patients)
ESCITALOPRAM (29 patients)
EFFEXOR (29 patients)
OLANZAPINE (29 patients)
SIMVASTATIN (28 patients)
BOTOX (28 patients)
ZYPREXA (28 patients)
FUROSEMIDE (28 patients)
CEREZYME (27 patients)
FENTANYL (27 patients)
LESCOL (26 patients)
LASIX (26 patients)
GABAPENTIN (25 patients)
STALEVO 100 (25 patients)
PROPOFOL (25 patients)
EPIVIR (25 patients)
RAMIPRIL (24 patients)
PARACETAMOL (24 patients)
VENLAFAXINE HCL (24 patients)
NEURONTIN (23 patients)
VALPROIC ACID (23 patients)
LIPITOR (22 patients)
TEGRETOL (22 patients)
METOCLOPRAMIDE (22 patients)
METHADONE HCL (22 patients)
CLONIDINE (22 patients)
THEOPHYLLINE (22 patients)
METHOTREXATE (22 patients)
ARICEPT (22 patients)
CELLCEPT (21 patients)
MICARDIS (20 patients)
OMNISCAN (20 patients)
MAGNEVIST (20 patients)
METHYLPREDNISOLONE (20 patients)
HYDROMORPHONE HCL (20 patients)
ATARAX (19 patients)
KREDEX (18 patients)
HYDROCHLOROTHIAZIDE (18 patients)
CYMBALTA (18 patients)
ALLOPURINOL (18 patients)
ONDANSETRON (17 patients)
GILENYA (17 patients)
DEXAMETHASONE (17 patients)
PLAVIX (17 patients)
DIGOXIN (17 patients)
METFORMIN HCL (17 patients)
CYCLOSPORINE (17 patients)
CARBAMAZEPINE (17 patients)
ATENOLOL (17 patients)
SPIRONOLACTONE (17 patients)
MYOZYME (16 patients)
ESOMEPRAZOLE MAGNESIUM (16 patients)
COMBIVIR (16 patients)
OXYCONTIN (16 patients)
LANSOPRAZOLE (16 patients)
VIOXX (16 patients)
NEBIVOLOL (16 patients)
COAPROVEL (16 patients)
BACTRIM (16 patients)
COMTAN (16 patients)
MIDAZOLAM HCL (16 patients)
FOLIC ACID (15 patients)
MODOPAR (15 patients)
AMITRIPTYLINE HCL (15 patients)
SALMETEROL (15 patients)
XALATAN (15 patients)
SINEMET (15 patients)
COUMADIN (15 patients)
ZOFRAN (15 patients)
KARDEGIC (15 patients)
PROPRANOLOL (15 patients)
ZERIT (14 patients)
NORVASC (14 patients)
NEVIRAPINE (14 patients)
DEPAKOTE (14 patients)
FOSAMAX (14 patients)
LIDOCAINE (14 patients)
DIOVAN (14 patients)
ZOCOR (14 patients)
SERESTA (14 patients)
CALCIUM CARBONATE (14 patients)
LEXAPRO (13 patients)
TRILEPTAL (13 patients)
CAPTOPRIL (13 patients)
VOLTAREN (13 patients)
STILNOX (13 patients)
PREDNISONE (13 patients)
LEXOMIL (13 patients)
CITALOPRAM (13 patients)
VITAMIN D (13 patients)
DURAGESIC-100 (13 patients)
BUPIVACAINE (13 patients)
METOPROLOL TARTRATE (13 patients)
HUMIRA (12 patients)
DILAUDID (12 patients)
ROHYPNOL (12 patients)
MEMANTINE HCL (12 patients)
SYNTHROID (12 patients)
LEVETIRACETAM (12 patients)
PHENOBARBITAL TAB (12 patients)
BUPROPION HCL (12 patients)
TYSABRI (11 patients)
WARFARIN SODIUM (11 patients)
ZANIDIP (11 patients)
LITHIUM (11 patients)
TAMOXIFEN CITRATE (11 patients)
FLUTICASONE PROPIONATE (11 patients)
DAFALGAN (11 patients)
VALTREX (11 patients)
MELOXICAM (11 patients)
IRON (11 patients)
PULMICORT (11 patients)
OPIOIDS (11 patients)
LANTUS (11 patients)
AMITRIP (11 patients)
AZATHIOPRINE (11 patients)
AVASTIN (11 patients)
DOCETAXEL (11 patients)
POTASSIUM CHLORIDE (11 patients)
CLOZARIL (11 patients)
IBUPROFEN (11 patients)
TRAZODONE HCL (11 patients)
CYCLOPHOSPHAMIDE (11 patients)
KLONOPIN (11 patients)
NEORAL (11 patients)
REQUIP (11 patients)
MADOPAR (10 patients)
MOVICOL (10 patients)
TRIATEC (10 patients)
EXELON (10 patients)
ROCURONIUM BROMIDE (10 patients)
ALBUTEROL (10 patients)
NASACORT (10 patients)
NORFLOXACIN (10 patients)
PHENYTOIN (10 patients)
BETASERON (10 patients)
ALENDRONATE SODIUM (10 patients)
NOROXIN (10 patients)
OMALIZUMAB (10 patients)
ETOPOSIDE (10 patients)
DEPAS (10 patients)
MORPHINE SULFATE (10 patients)
DIDANOSINE (10 patients)
DIPRIVAN (10 patients)
GLUCOPHAGE (10 patients)
ATORVASTATIN CALCIUM (10 patients)
PRAVASTATIN (10 patients)
VIRACEPT (10 patients)
TPN (10 patients)
ISOFLURANE (10 patients)
COZAAR (10 patients)
ULTRAM (10 patients)
ZOLPIDEM TARTRATE (10 patients)
DANTROLENE SODIUM (10 patients)
OXYCODONE HCL (10 patients)
CARBOPLATIN (10 patients)
ABILIFY (9 patients)
RIBAVIRIN (9 patients)
ACETYLSALICYLIC ACID SRT (9 patients)
CANDESARTAN CILEXETIL (9 patients)
CALCIUM (9 patients)
PANTOPRAZOLE SODIUM (9 patients)
AMBIEN (9 patients)
QUETIAPINE FUMARATE (9 patients)
FERROUS SULFATE TAB (9 patients)
LACTULOSE (9 patients)
PANTOPRAZOLE (9 patients)
LEPTICUR (9 patients)
LISINOPRIL (9 patients)
Most common side effects for patients taking ALMARL:
DEPRESSED LEVEL OF CONSCIOUSNESS (20 patients)
HALLUCINATION (15 patients)
FALL (13 patients)
HYPOGLYCAEMIA (13 patients)
PYREXIA (12 patients)
TREMOR (12 patients)
DIARRHOEA (11 patients)
HEPATIC FUNCTION ABNORMAL (11 patients)
PNEUMONIA (10 patients)
DYSARTHRIA (10 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (9 patients)
RENAL FAILURE ACUTE (9 patients)
LIVER DISORDER (9 patients)
CEREBRAL INFARCTION (8 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (8 patients)
DRUG INEFFECTIVE (8 patients)
RENAL IMPAIRMENT (8 patients)
HYPONATRAEMIA (8 patients)
INTERSTITIAL LUNG DISEASE (8 patients)
JAUNDICE (8 patients)
OEDEMA PERIPHERAL (8 patients)
CONDITION AGGRAVATED (7 patients)
DELIRIUM (7 patients)
DYSPHAGIA (7 patients)
DYSPNOEA (7 patients)
HYPOAESTHESIA (7 patients)
RHABDOMYOLYSIS (7 patients)
VOMITING (6 patients)
DELUSION (6 patients)
RESPIRATORY FAILURE (6 patients)
DYSKINESIA (6 patients)
SOMNOLENCE (6 patients)
HEPATIC NEOPLASM MALIGNANT (6 patients)
HYPERGLYCAEMIA (6 patients)
HYPOKALAEMIA (6 patients)
MOVEMENT DISORDER (6 patients)
MUSCULAR WEAKNESS (6 patients)
WHITE BLOOD CELL COUNT INCREASED (5 patients)
BLADDER CANCER (5 patients)
BLOOD ANTIDIURETIC HORMONE INCREASED (5 patients)
RESTLESSNESS (5 patients)
BLOOD OSMOLARITY DECREASED (5 patients)
PLEURAL EFFUSION (5 patients)
C-REACTIVE PROTEIN INCREASED (5 patients)
CONVULSION (5 patients)
RENAL DISORDER (5 patients)
VITH NERVE PARALYSIS (5 patients)
INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION (5 patients)
INTESTINAL OBSTRUCTION (5 patients)
SEPSIS (5 patients)
ROAD TRAFFIC ACCIDENT (5 patients)
MUSCULOSKELETAL PAIN (5 patients)
NAUSEA (5 patients)
ANOREXIA (4 patients)
ATELECTASIS (4 patients)
ATRIAL FIBRILLATION (4 patients)
ATRIOVENTRICULAR BLOCK (4 patients)
BLOOD CREATININE INCREASED (4 patients)
BRADYCARDIA (4 patients)
CARDIAC FAILURE (4 patients)
CONSTIPATION (4 patients)
DECREASED APPETITE (4 patients)
DEHYDRATION (4 patients)
DIZZINESS (4 patients)
PLATELET COUNT DECREASED (4 patients)
PAIN (4 patients)
HYPERTENSION (4 patients)
HYPOTHYROIDISM (4 patients)
ILEUS (4 patients)
METABOLIC ACIDOSIS (4 patients)
SMALL INTESTINE CARCINOMA (4 patients)
URINE OSMOLARITY INCREASED (4 patients)
ABASIA (3 patients)
AGGRESSION (3 patients)
PRURITUS (3 patients)
ANAEMIA (3 patients)
PULMONARY ALVEOLAR HAEMORRHAGE (3 patients)
WHITE BLOOD CELL COUNT DECREASED (3 patients)
ASTHMA (3 patients)
BLOOD BILIRUBIN INCREASED (3 patients)
RENAL FAILURE (3 patients)
BLOOD PRESSURE DECREASED (3 patients)
BLOOD PRESSURE INCREASED (3 patients)
VASCULITIS (3 patients)
CAROTID ARTERY STENOSIS (3 patients)
THERAPEUTIC AGENT TOXICITY (3 patients)
CHILLS (3 patients)
CHROMATURIA (3 patients)
PETECHIAE (3 patients)
CHRONIC LYMPHOCYTIC LEUKAEMIA (3 patients)
PORIOMANIA (3 patients)
RENAL ARTERY STENOSIS (3 patients)
PANCYTOPENIA (3 patients)
DRUG ERUPTION (3 patients)
SUDDEN ONSET OF SLEEP (3 patients)
DRUG WITHDRAWAL SYNDROME (3 patients)
VERTIGO (3 patients)
EPILEPSY (3 patients)
FACE OEDEMA (3 patients)
VOLVULUS (3 patients)
GENERALISED OEDEMA (3 patients)
GINGIVAL BLEEDING (3 patients)
HAEMORRHAGE SUBCUTANEOUS (3 patients)
HALLUCINATION, VISUAL (3 patients)
PSYCHIATRIC SYMPTOM (3 patients)
HEART RATE DECREASED (3 patients)
HELICOBACTER TEST POSITIVE (3 patients)
HEPATITIS FULMINANT (3 patients)
HYPERKALAEMIA (3 patients)
HYPOTENSION (3 patients)
IDIOPATHIC THROMBOCYTOPENIC PURPURA (3 patients)
LOSS OF CONSCIOUSNESS (3 patients)
SENSORY DISTURBANCE (3 patients)
LYMPHOMA (3 patients)
MALAISE (3 patients)
MARKEDLY REDUCED DIETARY INTAKE (3 patients)
RENAL TUBULAR DISORDER (3 patients)
NEOPLASM MALIGNANT (3 patients)
SINUS ARREST (3 patients)
ABDOMINAL DISCOMFORT (2 patients)
ABDOMINAL PAIN (2 patients)
ACUTE MYELOID LEUKAEMIA (2 patients)
STOMACH MASS (2 patients)
PERSONALITY CHANGE (2 patients)
AGITATION (2 patients)
ALTERED STATE OF CONSCIOUSNESS (2 patients)
ANAPHYLACTOID REACTION (2 patients)
ANGER (2 patients)
PRODUCTIVE COUGH (2 patients)
RENAL CYST (2 patients)
APHASIA (2 patients)
ASTHENIA (2 patients)
ATRIOVENTRICULAR BLOCK COMPLETE (2 patients)
THIRST (2 patients)
PROSTATE CANCER (2 patients)
BLOOD AMYLASE INCREASED (2 patients)
BLOOD UREA INCREASED (2 patients)
BODY TEMPERATURE INCREASED (2 patients)
SPEECH DISORDER (2 patients)
TUMOUR LYSIS SYNDROME (2 patients)
CEREBRAL HAEMORRHAGE (2 patients)
CHEST X-RAY ABNORMAL (2 patients)
COLON CANCER (2 patients)
COMA HEPATIC (2 patients)
COMPLETED SUICIDE (2 patients)
CONTUSION (2 patients)
PERFORMANCE STATUS DECREASED (2 patients)
DEFAECATION URGENCY (2 patients)
DEMENTIA ALZHEIMER'S TYPE (2 patients)
RASH PRURITIC (2 patients)
DIABETIC KETOACIDOSIS (2 patients)
DRUG INTERACTION (2 patients)
DRUG LEVEL INCREASED (2 patients)
DYSPEPSIA (2 patients)
DYSSTASIA (2 patients)
ELECTROCARDIOGRAM QT PROLONGED (2 patients)
STEVENS-JOHNSON SYNDROME (2 patients)
EPULIS (2 patients)
EXTRAOCULAR MUSCLE PARESIS (2 patients)
FACIAL PARESIS (2 patients)
FEAR (2 patients)
FEBRILE NEUTROPENIA (2 patients)
FEMORAL NECK FRACTURE (2 patients)
FOOT FRACTURE (2 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (2 patients)
GANGRENE (2 patients)
GASTRIC ULCER HAEMORRHAGE (2 patients)
GINGIVAL HYPERTROPHY (2 patients)
GLOSSOPTOSIS (2 patients)
PLEURISY (2 patients)
PHRENIC NERVE PARALYSIS (2 patients)
HAEMATEMESIS (2 patients)
HAEMATURIA (2 patients)
HAEMOGLOBIN DECREASED (2 patients)
POLLAKIURIA (2 patients)
ORAL INTAKE REDUCED (2 patients)
HEPATIC CYST (2 patients)
HEPATIC ENCEPHALOPATHY (2 patients)
HEPATITIS (2 patients)
HYPERREFLEXIA (2 patients)
HYPERTONIA (2 patients)
HYPERURICAEMIA (2 patients)
RASH PAPULAR (2 patients)
INITIAL INSOMNIA (2 patients)
RETINAL OEDEMA (2 patients)
INTESTINAL FUNCTIONAL DISORDER (2 patients)
RESPIRATION ABNORMAL (2 patients)
IRRITABILITY (2 patients)
RIB FRACTURE (2 patients)
LEG AMPUTATION (2 patients)
LYMPHADENOPATHY (2 patients)
METABOLIC ALKALOSIS (2 patients)
ORAL HERPES (2 patients)
TAKAYASU'S ARTERITIS (2 patients)
MOUTH HAEMORRHAGE (2 patients)
UNRESPONSIVE TO STIMULI (2 patients)
TOXIC SKIN ERUPTION (2 patients)
NEPHROLITHIASIS (2 patients)
SUICIDE ATTEMPT (2 patients)
VENTRICULAR FIBRILLATION (2 patients)
NEUTROPHIL COUNT DECREASED (2 patients)
UPPER RESPIRATORY TRACT INFECTION (2 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (2 patients)
SHOCK HAEMORRHAGIC (2 patients)
ABDOMEN CRUSHING (1 patients)
CARDIAC FAILURE CONGESTIVE (1 patients)
EOSINOPHILIC PNEUMONIA ACUTE (1 patients)
ESSENTIAL TREMOR (1 patients)
WRONG TECHNIQUE IN DRUG USAGE PROCESS (1 patients)
FUNGAL INFECTION (1 patients)

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