About this FactMed analysis covering adverse side effect reports of ALMARL patients who developed PYREXIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 12 individuals taking ALMARL reported PYREXIA to the FDA. A total of 227 ALMARL drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between ALMARL and PYREXIA. In doing so, we compare ALMARL with other drugs that cause PYREXIA, to help you evaluate whether or not ALMARL causes PYREXIA. Likewise, this page shows the most highly-reported side effects of ALMARL, so you can see if PYREXIA ranks among ALMARL's most well-known side effects.
Summary Statistics
Reports of ALMARL causing PYREXIA: 12
Reports of any side effect of ALMARL : 227
Percentage of ALMARL patients where PYREXIA is a reported side effect: 5.2863%

FDA reports of any drug causing PYREXIA : 111364
Average percentage for all medicated patients where PYREXIA is reported as a complication: 0.6980%

Physician opinion on ALMARL as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing ALMARL:
HYPERTENSION ( 76 patients )
PARKINSON'S DISEASE ( 8 patients )
ESSENTIAL TREMOR ( 6 patients )
ATRIAL FIBRILLATION ( 4 patients )
SCHIZOPHRENIA ( 2 patients )
TREMOR ( 2 patients )
ANGINA PECTORIS ( 2 patients )
DRUG USE FOR UNKNOWN INDICATION ( 2 patients )
PALPITATIONS ( 2 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 2 patients )
TACHYCARDIA ( 2 patients )
HYPERTROPHY ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with PYREXIA:

HUMIRA (7595 patients)
ASPIRIN (5953 patients)
REMICADE (5234 patients)
METHOTREXATE (5232 patients)
PREDNISONE (4893 patients)
PREDNISOLONE (4557 patients)
HEPARIN SODIUM INJECTION (4324 patients)
ENBREL (3597 patients)
ACETAMINOPHEN (3597 patients)
ZOMETA (3558 patients)
AVONEX (3381 patients)
LASIX (3343 patients)
OMEPRAZOLE (3235 patients)
FOSAMAX (3183 patients)
FOLIC ACID (3123 patients)
CYCLOPHOSPHAMIDE (2893 patients)
DEXAMETHASONE (2712 patients)
NEXIUM (2584 patients)
LIPITOR (2506 patients)
ALLOPURINOL (2390 patients)
VIOXX (2386 patients)
FUROSEMIDE (2225 patients)
TYSABRI (2085 patients)
CYCLOSPORINE (2084 patients)
PREDNISONE TAB (2069 patients)
LAMICTAL (2036 patients)
REVLIMID (2011 patients)
SYNTHROID (2005 patients)
EXJADE (1957 patients)
LISINOPRIL (1926 patients)
NEURONTIN (1875 patients)
COUMADIN (1867 patients)
DECADRON (1858 patients)
FLUOROURACIL (1855 patients)
SOLIRIS (1852 patients)
NEORAL (1851 patients)
IBUPROFEN (1821 patients)
OXYCONTIN (1817 patients)
PROTONIX (1801 patients)
NORVASC (1795 patients)
NEXAVAR (1792 patients)
AREDIA (1777 patients)
ZOFRAN (1744 patients)
LEVOTHYROXINE SODIUM (1724 patients)
CISPLATIN (1721 patients)
SIMVASTATIN (1710 patients)
CLOZARIL (1707 patients)
ATENOLOL (1688 patients)
SEROQUEL (1685 patients)
PRILOSEC (1664 patients)
XANAX (1646 patients)
POTASSIUM CHLORIDE (1630 patients)
VANCOMYCIN (1628 patients)
GLEEVEC (1612 patients)
TEGRETOL (1579 patients)
ACYCLOVIR (1579 patients)
ALBUTEROL (1571 patients)
RIBAVIRIN (1549 patients)
BACTRIM (1547 patients)
ZOLOFT (1539 patients)
AMBIEN (1527 patients)
ATIVAN (1510 patients)
CARBOPLATIN (1500 patients)
LORAZEPAM (1490 patients)
LANSOPRAZOLE (1456 patients)
PEGASYS (1452 patients)
PAXIL (1441 patients)
FLUCONAZOLE (1434 patients)
VITAMIN D (1421 patients)
PLAVIX (1418 patients)
VELCADE (1406 patients)
GABAPENTIN (1399 patients)
HYDROCHLOROTHIAZIDE (1378 patients)
MYCOPHENOLATE MOFETIL (1360 patients)
LYRICA (1337 patients)
LEVAQUIN (1331 patients)
CIPROFLOXACIN (1317 patients)
MORPHINE (1301 patients)
FAMOTIDINE (1292 patients)
DIOVAN (1290 patients)
CYTARABINE (1286 patients)
VICODIN (1276 patients)
CLONAZEPAM (1268 patients)
DIGOXIN (1263 patients)
REBIF (1245 patients)
CELEBREX (1242 patients)
OXYCODONE HCL (1232 patients)
FORTEO (1223 patients)
VINCRISTINE (1218 patients)
CALCIUM (1213 patients)
DOXORUBICIN HCL (1177 patients)
ZOCOR (1167 patients)
TAXOTERE (1156 patients)
NEUPOGEN (1156 patients)
WARFARIN SODIUM (1148 patients)
AMLODIPINE (1146 patients)
METFORMIN HCL (1138 patients)
PREVACID (1132 patients)
AMOXICILLIN (1126 patients)
BETASERON (1118 patients)
CLOZAPINE (1106 patients)
PERCOCET (1100 patients)
ETOPOSIDE (1099 patients)
TOPROL-XL (1093 patients)
IMMUCYST (1091 patients)
VOLTAREN (1078 patients)
MULTI-VITAMINS (1072 patients)
METHYLPREDNISOLONE (1069 patients)
ZANTAC (1065 patients)
AUGMENTIN '125' (1051 patients)
LEXAPRO (1047 patients)
BENADRYL (1040 patients)
RITUXIMAB (1037 patients)
TACROLIMUS (1037 patients)
CYMBALTA (1037 patients)
TYLENOL (CAPLET) (1033 patients)
DIAZEPAM (1027 patients)
SINGULAIR (1018 patients)
ACCUTANE (1010 patients)
LANTUS (1006 patients)
SOLU-MEDROL (1005 patients)
AVASTIN (1000 patients)
FENTANYL (1000 patients)
CRESTOR (986 patients)
TRAMADOL HCL (977 patients)
SYNAGIS (969 patients)
METOPROLOL TARTRATE (953 patients)
LEVOFLOXACIN (948 patients)
ZYPREXA (943 patients)
TAXOL (932 patients)
INSULIN (922 patients)
BEVACIZUMAB (921 patients)
AZATHIOPRINE (915 patients)
PACLITAXEL (915 patients)
PEG-INTRON (912 patients)
DIFLUCAN (912 patients)
TYLENOL (910 patients)
LOVENOX (906 patients)
XELODA (900 patients)
HEPARIN (899 patients)
CLARITHROMYCIN (897 patients)
AFINITOR (893 patients)
ARANESP (890 patients)
THYMOGLOBULIN (888 patients)
DURAGESIC-100 (887 patients)
RECLAST (886 patients)
NEULASTA (885 patients)
EFFEXOR (883 patients)
MAGNESIUM OXIDE (879 patients)
PREDONINE (878 patients)
OXALIPLATIN (878 patients)
COMPAZINE (870 patients)
FLAGYL (867 patients)
ALPRAZOLAM (860 patients)
LOXONIN (852 patients)
ZYRTEC (852 patients)
MULTI-VITAMIN (842 patients)
RISPERDAL (840 patients)
ADVAIR DISKUS 100/50 (840 patients)
DEPAKENE (836 patients)
DOCETAXEL (836 patients)
VALTREX (820 patients)
CALCIUM CARBONATE (817 patients)
PROGRAF (812 patients)
PANTOPRAZOLE (810 patients)
CELLCEPT (798 patients)
ZITHROMAX (798 patients)
THALIDOMIDE (791 patients)
KLONOPIN (788 patients)
BACLOFEN (782 patients)
KETEK (782 patients)
LAMIVUDINE (775 patients)
GEMZAR (775 patients)
DIANEAL (770 patients)
PROZAC (765 patients)
ROCEPHIN (760 patients)
COPEGUS (759 patients)
KALETRA (756 patients)
LORTAB (753 patients)
SPIRIVA (751 patients)
WELLBUTRIN (750 patients)
CELEXA (748 patients)
COLACE (748 patients)
RANITIDINE (748 patients)
MORPHINE SULFATE (745 patients)
MUCOSTA (742 patients)
ALDACTONE (742 patients)
CAPECITABINE (739 patients)
CERTICAN (735 patients)
BYETTA (730 patients)
REBETOL (726 patients)
VITAMIN B-12 (726 patients)
DILAUDID (724 patients)
ENALAPRIL MALEATE (716 patients)
SPIRONOLACTONE (715 patients)
AMITRIPTYLINE HCL (707 patients)
PARACETAMOL (706 patients)
RAMIPRIL (691 patients)
REGLAN (690 patients)
NYSTATIN (688 patients)
ONDANSETRON (682 patients)
PREMARIN (681 patients)
METRONIDAZOLE (670 patients)
TASIGNA (670 patients)
LEUCOVORIN CALCIUM (670 patients)
AVELOX (669 patients)
PEPCID (665 patients)
CARBAMAZEPINE (664 patients)
NITROGLYCERIN (664 patients)
ALLEGRA (661 patients)
Most common side effects for patients taking ALMARL:
DEPRESSED LEVEL OF CONSCIOUSNESS (20 patients)
HALLUCINATION (15 patients)
FALL (13 patients)
HYPOGLYCAEMIA (13 patients)
PYREXIA (12 patients)
TREMOR (12 patients)
DIARRHOEA (11 patients)
HEPATIC FUNCTION ABNORMAL (11 patients)
PNEUMONIA (10 patients)
DYSARTHRIA (10 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (9 patients)
RENAL FAILURE ACUTE (9 patients)
LIVER DISORDER (9 patients)
CEREBRAL INFARCTION (8 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (8 patients)
DRUG INEFFECTIVE (8 patients)
RENAL IMPAIRMENT (8 patients)
HYPONATRAEMIA (8 patients)
INTERSTITIAL LUNG DISEASE (8 patients)
JAUNDICE (8 patients)
OEDEMA PERIPHERAL (8 patients)
CONDITION AGGRAVATED (7 patients)
DELIRIUM (7 patients)
DYSPHAGIA (7 patients)
DYSPNOEA (7 patients)
HYPOAESTHESIA (7 patients)
RHABDOMYOLYSIS (7 patients)
VOMITING (6 patients)
DELUSION (6 patients)
RESPIRATORY FAILURE (6 patients)
DYSKINESIA (6 patients)
SOMNOLENCE (6 patients)
HEPATIC NEOPLASM MALIGNANT (6 patients)
HYPERGLYCAEMIA (6 patients)
HYPOKALAEMIA (6 patients)
MOVEMENT DISORDER (6 patients)
MUSCULAR WEAKNESS (6 patients)
WHITE BLOOD CELL COUNT INCREASED (5 patients)
BLADDER CANCER (5 patients)
BLOOD ANTIDIURETIC HORMONE INCREASED (5 patients)
RESTLESSNESS (5 patients)
BLOOD OSMOLARITY DECREASED (5 patients)
PLEURAL EFFUSION (5 patients)
C-REACTIVE PROTEIN INCREASED (5 patients)
CONVULSION (5 patients)
RENAL DISORDER (5 patients)
VITH NERVE PARALYSIS (5 patients)
INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION (5 patients)
INTESTINAL OBSTRUCTION (5 patients)
SEPSIS (5 patients)
ROAD TRAFFIC ACCIDENT (5 patients)
MUSCULOSKELETAL PAIN (5 patients)
NAUSEA (5 patients)
ANOREXIA (4 patients)
ATELECTASIS (4 patients)
ATRIAL FIBRILLATION (4 patients)
ATRIOVENTRICULAR BLOCK (4 patients)
BLOOD CREATININE INCREASED (4 patients)
BRADYCARDIA (4 patients)
CARDIAC FAILURE (4 patients)
CONSTIPATION (4 patients)
DECREASED APPETITE (4 patients)
DEHYDRATION (4 patients)
DIZZINESS (4 patients)
PLATELET COUNT DECREASED (4 patients)
PAIN (4 patients)
HYPERTENSION (4 patients)
HYPOTHYROIDISM (4 patients)
ILEUS (4 patients)
METABOLIC ACIDOSIS (4 patients)
SMALL INTESTINE CARCINOMA (4 patients)
URINE OSMOLARITY INCREASED (4 patients)
ABASIA (3 patients)
AGGRESSION (3 patients)
PRURITUS (3 patients)
ANAEMIA (3 patients)
PULMONARY ALVEOLAR HAEMORRHAGE (3 patients)
WHITE BLOOD CELL COUNT DECREASED (3 patients)
ASTHMA (3 patients)
BLOOD BILIRUBIN INCREASED (3 patients)
RENAL FAILURE (3 patients)
BLOOD PRESSURE DECREASED (3 patients)
BLOOD PRESSURE INCREASED (3 patients)
VASCULITIS (3 patients)
CAROTID ARTERY STENOSIS (3 patients)
THERAPEUTIC AGENT TOXICITY (3 patients)
CHILLS (3 patients)
CHROMATURIA (3 patients)
PETECHIAE (3 patients)
CHRONIC LYMPHOCYTIC LEUKAEMIA (3 patients)
PORIOMANIA (3 patients)
RENAL ARTERY STENOSIS (3 patients)
PANCYTOPENIA (3 patients)
DRUG ERUPTION (3 patients)
SUDDEN ONSET OF SLEEP (3 patients)
DRUG WITHDRAWAL SYNDROME (3 patients)
VERTIGO (3 patients)
EPILEPSY (3 patients)
FACE OEDEMA (3 patients)
VOLVULUS (3 patients)
GENERALISED OEDEMA (3 patients)
GINGIVAL BLEEDING (3 patients)
HAEMORRHAGE SUBCUTANEOUS (3 patients)
HALLUCINATION, VISUAL (3 patients)
PSYCHIATRIC SYMPTOM (3 patients)
HEART RATE DECREASED (3 patients)
HELICOBACTER TEST POSITIVE (3 patients)
HEPATITIS FULMINANT (3 patients)
HYPERKALAEMIA (3 patients)
HYPOTENSION (3 patients)
IDIOPATHIC THROMBOCYTOPENIC PURPURA (3 patients)
LOSS OF CONSCIOUSNESS (3 patients)
SENSORY DISTURBANCE (3 patients)
LYMPHOMA (3 patients)
MALAISE (3 patients)
MARKEDLY REDUCED DIETARY INTAKE (3 patients)
RENAL TUBULAR DISORDER (3 patients)
NEOPLASM MALIGNANT (3 patients)
SINUS ARREST (3 patients)
ABDOMINAL DISCOMFORT (2 patients)
ABDOMINAL PAIN (2 patients)
ACUTE MYELOID LEUKAEMIA (2 patients)
STOMACH MASS (2 patients)
PERSONALITY CHANGE (2 patients)
AGITATION (2 patients)
ALTERED STATE OF CONSCIOUSNESS (2 patients)
ANAPHYLACTOID REACTION (2 patients)
ANGER (2 patients)
PRODUCTIVE COUGH (2 patients)
RENAL CYST (2 patients)
APHASIA (2 patients)
ASTHENIA (2 patients)
ATRIOVENTRICULAR BLOCK COMPLETE (2 patients)
THIRST (2 patients)
PROSTATE CANCER (2 patients)
BLOOD AMYLASE INCREASED (2 patients)
BLOOD UREA INCREASED (2 patients)
BODY TEMPERATURE INCREASED (2 patients)
SPEECH DISORDER (2 patients)
TUMOUR LYSIS SYNDROME (2 patients)
CEREBRAL HAEMORRHAGE (2 patients)
CHEST X-RAY ABNORMAL (2 patients)
COLON CANCER (2 patients)
COMA HEPATIC (2 patients)
COMPLETED SUICIDE (2 patients)
CONTUSION (2 patients)
PERFORMANCE STATUS DECREASED (2 patients)
DEFAECATION URGENCY (2 patients)
DEMENTIA ALZHEIMER'S TYPE (2 patients)
RASH PRURITIC (2 patients)
DIABETIC KETOACIDOSIS (2 patients)
DRUG INTERACTION (2 patients)
DRUG LEVEL INCREASED (2 patients)
DYSPEPSIA (2 patients)
DYSSTASIA (2 patients)
ELECTROCARDIOGRAM QT PROLONGED (2 patients)
STEVENS-JOHNSON SYNDROME (2 patients)
EPULIS (2 patients)
EXTRAOCULAR MUSCLE PARESIS (2 patients)
FACIAL PARESIS (2 patients)
FEAR (2 patients)
FEBRILE NEUTROPENIA (2 patients)
FEMORAL NECK FRACTURE (2 patients)
FOOT FRACTURE (2 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (2 patients)
GANGRENE (2 patients)
GASTRIC ULCER HAEMORRHAGE (2 patients)
GINGIVAL HYPERTROPHY (2 patients)
GLOSSOPTOSIS (2 patients)
PLEURISY (2 patients)
PHRENIC NERVE PARALYSIS (2 patients)
HAEMATEMESIS (2 patients)
HAEMATURIA (2 patients)
HAEMOGLOBIN DECREASED (2 patients)
POLLAKIURIA (2 patients)
ORAL INTAKE REDUCED (2 patients)
HEPATIC CYST (2 patients)
HEPATIC ENCEPHALOPATHY (2 patients)
HEPATITIS (2 patients)
HYPERREFLEXIA (2 patients)
HYPERTONIA (2 patients)
HYPERURICAEMIA (2 patients)
RASH PAPULAR (2 patients)
INITIAL INSOMNIA (2 patients)
RETINAL OEDEMA (2 patients)
INTESTINAL FUNCTIONAL DISORDER (2 patients)
RESPIRATION ABNORMAL (2 patients)
IRRITABILITY (2 patients)
RIB FRACTURE (2 patients)
LEG AMPUTATION (2 patients)
LYMPHADENOPATHY (2 patients)
METABOLIC ALKALOSIS (2 patients)
ORAL HERPES (2 patients)
TAKAYASU'S ARTERITIS (2 patients)
MOUTH HAEMORRHAGE (2 patients)
UNRESPONSIVE TO STIMULI (2 patients)
TOXIC SKIN ERUPTION (2 patients)
NEPHROLITHIASIS (2 patients)
SUICIDE ATTEMPT (2 patients)
VENTRICULAR FIBRILLATION (2 patients)
NEUTROPHIL COUNT DECREASED (2 patients)
UPPER RESPIRATORY TRACT INFECTION (2 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (2 patients)
SHOCK HAEMORRHAGIC (2 patients)
ABDOMEN CRUSHING (1 patients)
CARDIAC FAILURE CONGESTIVE (1 patients)
EOSINOPHILIC PNEUMONIA ACUTE (1 patients)
ESSENTIAL TREMOR (1 patients)
WRONG TECHNIQUE IN DRUG USAGE PROCESS (1 patients)
FUNGAL INFECTION (1 patients)

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