About this FactMed analysis covering adverse side effect reports of CENTRUM patients who developed AKINESIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 5 individuals taking CENTRUM reported AKINESIA to the FDA. A total of 3611 CENTRUM drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between CENTRUM and AKINESIA. In doing so, we compare CENTRUM with other drugs that cause AKINESIA, to help you evaluate whether or not CENTRUM causes AKINESIA. Likewise, this page shows the most highly-reported side effects of CENTRUM, so you can see if AKINESIA ranks among CENTRUM's most well-known side effects.
Summary Statistics
Reports of CENTRUM causing AKINESIA: 5
Reports of any side effect of CENTRUM : 3611
Percentage of CENTRUM patients where AKINESIA is a reported side effect: 0.1385%

FDA reports of any drug causing AKINESIA : 753
Average percentage for all medicated patients where AKINESIA is reported as a complication: 0.0047%

Physician opinion on CENTRUM as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing CENTRUM:
DRUG USE FOR UNKNOWN INDICATION ( 198 patients )
VITAMIN SUPPLEMENTATION ( 179 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 162 patients )
SUPPLEMENTATION THERAPY ( 58 patients )
MEDICAL DIET ( 31 patients )
ROUTINE HEALTH MAINTENANCE ( 20 patients )
PROPHYLAXIS ( 9 patients )
NUTRITIONAL SUPPORT ( 8 patients )
GENERAL PHYSICAL CONDITION ( 6 patients )
ANAEMIA ( 3 patients )
HYPOVITAMINOSIS ( 3 patients )
DEHYDRATION ( 2 patients )
ENERGY INCREASED ( 2 patients )
HYPOTHYROIDISM ( 2 patients )
PROPHYLAXIS OF NEURAL TUBE DEFECT ( 2 patients )
SURGERY ( 2 patients )
MACULAR DEGENERATION ( 1 patients )
MINERAL SUPPLEMENTATION ( 1 patients )
APPETITE DISORDER ( 1 patients )
SHORT-BOWEL SYNDROME ( 1 patients )
GASTRIC BYPASS ( 1 patients )
ILL-DEFINED DISORDER ( 1 patients )
MULTI-VITAMIN DEFICIENCY ( 1 patients )
CROHN'S DISEASE ( 1 patients )
SEASONAL ALLERGY ( 1 patients )
FATIGUE ( 1 patients )
SPINAL COMPRESSION FRACTURE ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with AKINESIA:

MODOPAR (292 patients)
EFFEXOR (145 patients)
XANAX (129 patients)
VIOXX (116 patients)
STALEVO 100 (111 patients)
ASPIRIN (73 patients)
PERGOLIDE MESYLATE (56 patients)
SINEMET (55 patients)
RISPERDAL (54 patients)
ATHYMIL (52 patients)
COMTAN (45 patients)
MADOPAR (41 patients)
LORAZEPAM (40 patients)
MADOPAR DISPERSIBLE (39 patients)
IMOVANE (38 patients)
ZYPREXA (37 patients)
ATARAX (37 patients)
VALPROATE SODIUM (36 patients)
CLOZAPINE (31 patients)
DEPAKOTE (30 patients)
CITALOPRAM HYDROBROMIDE (29 patients)
CLOBAZAM (29 patients)
FUROSEMIDE (28 patients)
REQUIP (28 patients)
PARLODEL (27 patients)
EXELON (27 patients)
PAXIL (26 patients)
DIGOXIN (25 patients)
LASIX (25 patients)
ERYTHROMYCIN (25 patients)
SEROQUEL (25 patients)
LAMOTRIGINE (25 patients)
RISPERIDONE (24 patients)
GENTAMICIN (24 patients)
PHENYTOIN (23 patients)
AMANTADINE HCL (23 patients)
ACETAMINOPHEN (21 patients)
HALDOL (21 patients)
DIAZEPAM (20 patients)
VALTREX (20 patients)
OMEPRAZOLE (19 patients)
PAROXETINE HCL (19 patients)
ACETAMINOPHEN AND TRAMADOL HCL (18 patients)
CEFOTAXIME (18 patients)
SPIRONOLACTONE (18 patients)
LEVOTHYROXINE SODIUM (18 patients)
TEGRETOL (17 patients)
PREDNISOLONE (17 patients)
DEPAKENE (17 patients)
HALOPERIDOL (17 patients)
SIMVASTATIN (16 patients)
NITROGLYCERIN (16 patients)
ZOLOFT (15 patients)
PIPERACILLIN (15 patients)
LIPITOR (15 patients)
LEXOMIL (14 patients)
CLOPIDOGREL (14 patients)
OLANZAPINE (14 patients)
CABERGOLINE (14 patients)
TEMESTA (14 patients)
CLONAZEPAM (14 patients)
IBUPROFEN (14 patients)
NEURONTIN (13 patients)
LEVODOPA (13 patients)
WARFARIN SODIUM (13 patients)
SERENACE (13 patients)
OXYCONTIN (13 patients)
MEMANTINE HCL (13 patients)
ATENOLOL (13 patients)
DIOVAN (12 patients)
HIZENTRA (12 patients)
PRAMIPEXOLE DIHYDROCHLORIDE (12 patients)
ALBUTEROL (12 patients)
CELEBREX (12 patients)
HEPARIN (12 patients)
SEROQUEL XR (12 patients)
ENOXAPARIN SODIUM (12 patients)
ATORVASTATIN CALCIUM (12 patients)
ABILIFY (11 patients)
PLAVIX (11 patients)
FLUOXETINE (11 patients)
LOXAPINE HCL (11 patients)
COREG (11 patients)
TAXOTERE (11 patients)
GLEEVEC (11 patients)
VENLAFAXINE (11 patients)
PREVACID (11 patients)
CAPTOPRIL (11 patients)
CIPRO (11 patients)
CYCLOSPORINE (11 patients)
LANTUS (10 patients)
SYNTHROID (10 patients)
ACTONEL (10 patients)
MIRAPEX (10 patients)
KETOCONAZOLE (10 patients)
ANTIBIOTICS (10 patients)
ARICEPT (10 patients)
HEPARIN SODIUM INJECTION (10 patients)
AVONEX (10 patients)
RAMIPRIL (9 patients)
INSULIN (9 patients)
NECYRANE (9 patients)
MORPHINE (9 patients)
FERROUS SULFATE TAB (9 patients)
PRAZEPAM (9 patients)
DONEPEZIL HCL (9 patients)
CARBOCISTEINE (9 patients)
EXTAVIA (9 patients)
BROMOCRIPTINE MESYLATE (9 patients)
AMBIEN (9 patients)
AMOXICILLIN (9 patients)
RISPERDAL CONSTA (9 patients)
LAMICTAL (9 patients)
SINGULAIR (9 patients)
ECONAZOLE NITRATE (9 patients)
ARTANE (9 patients)
FOLIC ACID (9 patients)
PRAMIPEXOLE DIHYCHLLORIDE (9 patients)
LISINOPRIL (9 patients)
CEFUROXIME (9 patients)
LYSOPAINE (9 patients)
PRILOSEC (9 patients)
HYDROCHLOROTHIAZIDE (9 patients)
SANDIMMUNE (9 patients)
CYMBALTA (8 patients)
ELUDRIL (8 patients)
MIRTAZAPINE (8 patients)
SOLANAX (8 patients)
EPINEPHRINE (8 patients)
TYLENOL (CAPLET) (8 patients)
CIATYL Z (8 patients)
TRAMAL (8 patients)
AMIODARONE HCL (8 patients)
COUMADIN (8 patients)
NEUROCIL (8 patients)
OXAZEPAM (8 patients)
LEVEMIR (8 patients)
AVANDIA (8 patients)
NEXIUM (8 patients)
PROTONIX (8 patients)
ZOCOR (8 patients)
WELLBUTRIN (8 patients)
BIPERIDEN HYDROCHLORIDE TAB (8 patients)
METFORMIN HCL (7 patients)
NORVASC (7 patients)
METOPROLOL (7 patients)
TRIVASTAL (7 patients)
ZANAFLEX (7 patients)
HUMIRA (7 patients)
ALDACTONE (7 patients)
SOLU-CORTEF (7 patients)
ALLOPURINOL (7 patients)
TRIHEXYPHENIDYL HCL (7 patients)
PREVISCAN (7 patients)
DOPAMINE HCL (7 patients)
SERTRALINE HCL (7 patients)
THIOPENTAL SODIUM (7 patients)
ENALAPRIL MALEATE (7 patients)
BISOPROLOL FUMARATE (7 patients)
TRAZODONE HCL (7 patients)
LITHIUM CARBONATE (7 patients)
TYLENOL (7 patients)
TRANXENE (7 patients)
POTASSIUM CHLORIDE (7 patients)
CEFOTAXIME SODIUM (7 patients)
PREDONINE (7 patients)
ISOSORBIDE DINITRATE (7 patients)
CYTARABINE (7 patients)
VITAMIN D (7 patients)
CARBIDOPA AND LEVODOPA (6 patients)
LOVENOX (6 patients)
ACETYLSALICYLIC ACID SRT (6 patients)
ESCITALOPRAM (6 patients)
DEXAMETHASONE TAB (6 patients)
SERTRALINE HYDROCHLORIDE (6 patients)
EVEROLIMUS (6 patients)
TASMAR (6 patients)
ALPRAZOLAM (6 patients)
MANTADIX (6 patients)
PRAZINE (6 patients)
HERCEPTIN (6 patients)
DEROXAT (6 patients)
AMLODIPINE (6 patients)
METHYLPREDNISOLONE (6 patients)
PURSENNID (6 patients)
REMICADE (6 patients)
SILECE (6 patients)
ZOVIRAX (6 patients)
MYCOPHENOLATE MOFETIL (6 patients)
ARAVA (6 patients)
LEPTICUR (6 patients)
CARBAMAZEPINE (6 patients)
TOBRAMYCIN (6 patients)
SYMMETREL (6 patients)
ATIVAN (6 patients)
ATORVASTATIN (6 patients)
CIPRALEX (ESCITALOPRAM) (6 patients)
LYRICA (6 patients)
CLARITHROMYCIN (6 patients)
CITALOPRAM (6 patients)
VANCOMYCIN (6 patients)
HEPTAMINOL (6 patients)
AZILECT (6 patients)
HUMALOG (6 patients)
PREDNISONE TAB (6 patients)
PROPRANOLOL (6 patients)
PROCTOLOG (6 patients)
INTETRIX (6 patients)
RANITIDINE (6 patients)
MS CONTIN (5 patients)
Most common side effects for patients taking CENTRUM:
PAIN (371 patients)
NAUSEA (347 patients)
FATIGUE (330 patients)
ANXIETY (322 patients)
DYSPNOEA (294 patients)
DIZZINESS (289 patients)
ASTHENIA (256 patients)
HEADACHE (254 patients)
BACK PAIN (254 patients)
FALL (248 patients)
ANAEMIA (235 patients)
DEPRESSION (217 patients)
DIARRHOEA (216 patients)
ARTHRALGIA (210 patients)
HYPERTENSION (195 patients)
PAIN IN EXTREMITY (187 patients)
VOMITING (186 patients)
WEIGHT DECREASED (170 patients)
CHEST PAIN (170 patients)
ATRIAL FIBRILLATION (164 patients)
PNEUMONIA (161 patients)
URINARY TRACT INFECTION (158 patients)
OEDEMA PERIPHERAL (153 patients)
DRUG INEFFECTIVE (152 patients)
COUGH (149 patients)
MYOCARDIAL INFARCTION (148 patients)
CARDIAC FAILURE CONGESTIVE (145 patients)
CONSTIPATION (144 patients)
ABDOMINAL PAIN (136 patients)
PYREXIA (134 patients)
DEHYDRATION (132 patients)
RASH (131 patients)
OSTEOARTHRITIS (131 patients)
CEREBROVASCULAR ACCIDENT (128 patients)
MALAISE (126 patients)
FEELING ABNORMAL (126 patients)
HYPOAESTHESIA (123 patients)
WEIGHT INCREASED (121 patients)
BONE DISORDER (120 patients)
VISION BLURRED (119 patients)
MUSCLE SPASMS (116 patients)
ABDOMINAL PAIN UPPER (115 patients)
ARTHRITIS (115 patients)
HYPOTENSION (109 patients)
INSOMNIA (109 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (107 patients)
PRURITUS (105 patients)
FEMUR FRACTURE (105 patients)
DECREASED APPETITE (101 patients)
PARAESTHESIA (101 patients)
RENAL FAILURE (100 patients)
CORONARY ARTERY DISEASE (99 patients)
MUSCULOSKELETAL PAIN (98 patients)
NECK PAIN (98 patients)
MYALGIA (98 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (97 patients)
OSTEOPOROSIS (97 patients)
EMOTIONAL DISTRESS (97 patients)
HYPERHIDROSIS (96 patients)
OSTEONECROSIS OF JAW (95 patients)
INJURY (94 patients)
DRY MOUTH (94 patients)
BLOOD GLUCOSE INCREASED (93 patients)
TREMOR (92 patients)
CONFUSIONAL STATE (92 patients)
DYSPHAGIA (91 patients)
OSTEONECROSIS (90 patients)
DEEP VEIN THROMBOSIS (90 patients)
GAIT DISTURBANCE (89 patients)
DEATH (88 patients)
INTERVERTEBRAL DISC DEGENERATION (88 patients)
RECTAL HAEMORRHAGE (88 patients)
PAIN IN JAW (86 patients)
NEUROPATHY PERIPHERAL (85 patients)
BLOOD PRESSURE INCREASED (85 patients)
HYPERLIPIDAEMIA (85 patients)
RENAL FAILURE ACUTE (85 patients)
INFECTION (84 patients)
MITRAL VALVE INCOMPETENCE (84 patients)
SYNCOPE (84 patients)
PLEURAL EFFUSION (83 patients)
BALANCE DISORDER (82 patients)
SPINAL OSTEOARTHRITIS (79 patients)
HAEMOGLOBIN DECREASED (77 patients)
CHOLELITHIASIS (77 patients)
OSTEOMYELITIS (76 patients)
CHEST DISCOMFORT (76 patients)
PALPITATIONS (75 patients)
HAEMORRHOIDS (74 patients)
ATELECTASIS (74 patients)
NASOPHARYNGITIS (73 patients)
TOOTH EXTRACTION (73 patients)
ABDOMINAL DISCOMFORT (72 patients)
SEPSIS (70 patients)
FLUSHING (70 patients)
SOMNOLENCE (68 patients)
COLONIC POLYP (66 patients)
PULMONARY EMBOLISM (65 patients)
DIVERTICULUM (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (65 patients)
CONTUSION (64 patients)
JOINT SWELLING (64 patients)
BRONCHITIS (63 patients)
HYPERSENSITIVITY (63 patients)
CONVULSION (63 patients)
TACHYCARDIA (62 patients)
ALOPECIA (62 patients)
AMNESIA (62 patients)
SPINAL COLUMN STENOSIS (61 patients)
THROMBOCYTOPENIA (60 patients)
ERYTHEMA (59 patients)
MUSCULAR WEAKNESS (59 patients)
CONDITION AGGRAVATED (59 patients)
RADICULOPATHY (58 patients)
DEFORMITY (58 patients)
DENTAL CARIES (58 patients)
HYPOKALAEMIA (58 patients)
GASTRITIS (58 patients)
URINARY RETENTION (55 patients)
ANHEDONIA (55 patients)
SINUSITIS (55 patients)
STOMATITIS (55 patients)
CHILLS (54 patients)
TRICUSPID VALVE INCOMPETENCE (54 patients)
LYMPHADENOPATHY (54 patients)
ARTHROPATHY (54 patients)
DYSURIA (53 patients)
PANCYTOPENIA (53 patients)
ASTHMA (53 patients)
NERVOUSNESS (53 patients)
ABASIA (52 patients)
DIABETES MELLITUS (52 patients)
MENISCUS LESION (52 patients)
GASTROINTESTINAL DISORDER (52 patients)
TOOTH FRACTURE (52 patients)
HOT FLUSH (51 patients)
SPINAL COMPRESSION FRACTURE (51 patients)
HAEMORRHAGE (51 patients)
SINUS DISORDER (51 patients)
URTICARIA (50 patients)
INJECTION SITE PAIN (50 patients)
MUSCULOSKELETAL DISCOMFORT (50 patients)
BLOOD CHOLESTEROL INCREASED (49 patients)
POLLAKIURIA (49 patients)
DRY SKIN (49 patients)
FEELING HOT (49 patients)
DRUG INTERACTION (49 patients)
BONE PAIN (48 patients)
FOOT DEFORMITY (48 patients)
EYE DISORDER (47 patients)
CEREBRAL ATROPHY (47 patients)
RHINITIS ALLERGIC (47 patients)
LOW TURNOVER OSTEOPATHY (47 patients)
LUNG NEOPLASM (47 patients)
DIPLOPIA (47 patients)
DECREASED INTEREST (47 patients)
HEART RATE INCREASED (46 patients)
ABDOMINAL DISTENSION (46 patients)
CARDIOMEGALY (46 patients)
DYSPEPSIA (46 patients)
HYPERGLYCAEMIA (46 patients)
OSTEOPENIA (46 patients)
HIATUS HERNIA (46 patients)
HYPOPHAGIA (46 patients)
MOUTH ULCERATION (45 patients)
VISUAL IMPAIRMENT (45 patients)
ORAL PAIN (45 patients)
SWELLING (45 patients)
HYPERKERATOSIS (45 patients)
RHINORRHOEA (44 patients)
HAEMATOCRIT DECREASED (44 patients)
TRANSIENT ISCHAEMIC ATTACK (44 patients)
HAEMATOCHEZIA (43 patients)
MEMORY IMPAIRMENT (43 patients)
GASTROINTESTINAL HAEMORRHAGE (43 patients)
LOSS OF CONSCIOUSNESS (43 patients)
KYPHOSIS (43 patients)
MULTIPLE MYELOMA (43 patients)
ECONOMIC PROBLEM (42 patients)
ROTATOR CUFF SYNDROME (42 patients)
MENTAL STATUS CHANGES (42 patients)
OROPHARYNGEAL PAIN (42 patients)
DRUG DOSE OMISSION (42 patients)
DYSPNOEA EXERTIONAL (42 patients)
HIP FRACTURE (42 patients)
RESPIRATORY FAILURE (42 patients)
BUNDLE BRANCH BLOCK LEFT (42 patients)
VENTRICULAR TACHYCARDIA (42 patients)
CARPAL TUNNEL SYNDROME (41 patients)
INTERVERTEBRAL DISC PROTRUSION (41 patients)
SWELLING FACE (41 patients)
STRESS (41 patients)
EPISTAXIS (41 patients)
VENTRICULAR EXTRASYSTOLES (41 patients)
BLOOD CALCIUM INCREASED (40 patients)
HERPES ZOSTER (40 patients)
ILL-DEFINED DISORDER (40 patients)
CARDIAC DISORDER (40 patients)
STRESS FRACTURE (40 patients)
DENTAL FISTULA (39 patients)
PANCREATITIS (39 patients)
BLOOD CREATININE INCREASED (39 patients)
HYPOTHYROIDISM (39 patients)
PULMONARY HYPERTENSION (39 patients)
UNRESPONSIVE TO STIMULI (39 patients)
DYSPHONIA (39 patients)
BLOOD PRESSURE DECREASED (39 patients)
BASAL CELL CARCINOMA (38 patients)
LUNG INFILTRATION (38 patients)
HEPATIC ENZYME INCREASED (37 patients)

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Issue Description / Topic Timestamp
QUESTION
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QUESTION
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QUESTION
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QUESTION
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QUESTION
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QUESTION
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QUESTION
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QUESTION
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QUESTION
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QUESTION
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CONCERN
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QUESTION
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QUESTION
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QUESTION
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QUESTION
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QUESTION
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QUESTION
ASTHMA
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