Is DUODENAL PERFORATION a side effect of CLARITHROMYCIN ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of CLARITHROMYCIN patients who developed DUODENAL PERFORATION.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 4 individuals taking CLARITHROMYCIN reported DUODENAL PERFORATION to the FDA. A total of 10851 CLARITHROMYCIN drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between CLARITHROMYCIN and DUODENAL PERFORATION. In doing so, we compare CLARITHROMYCIN with other drugs that cause DUODENAL PERFORATION, to help you evaluate whether or not CLARITHROMYCIN causes DUODENAL PERFORATION. Likewise, this page shows the most highly-reported side effects of CLARITHROMYCIN, so you can see if DUODENAL PERFORATION ranks among CLARITHROMYCIN's most well-known side effects.

Summary Statistics
Reports of CLARITHROMYCIN causing DUODENAL PERFORATION: 4
Reports of any side effect of CLARITHROMYCIN : 10851
Percentage of CLARITHROMYCIN patients where DUODENAL PERFORATION is a reported side effect: 0.0369%

FDA reports of any drug causing DUODENAL PERFORATION : 311
Average percentage for all medicated patients where DUODENAL PERFORATION is reported as a complication: 0.0019%

Physician opinion on CLARITHROMYCIN as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing CLARITHROMYCIN:

PRODUCT USED FOR UNKNOWN INDICATION ( 617 patients )
HELICOBACTER INFECTION ( 595 patients )
PNEUMONIA ( 558 patients )
LOWER RESPIRATORY TRACT INFECTION ( 527 patients )
DRUG USE FOR UNKNOWN INDICATION ( 432 patients )
BRONCHITIS ( 378 patients )
MYCOBACTERIUM AVIUM COMPLEX INFECTION ( 216 patients )
RESPIRATORY TRACT INFECTION ( 197 patients )
SINUSITIS ( 157 patients )
INFECTION ( 138 patients )
UPPER RESPIRATORY TRACT INFECTION ( 133 patients )
PROPHYLAXIS ( 129 patients )
ATYPICAL MYCOBACTERIAL INFECTION ( 128 patients )
NASOPHARYNGITIS ( 117 patients )
UPPER RESPIRATORY TRACT INFLAMMATION ( 107 patients )
PYREXIA ( 98 patients )
HELICOBACTER GASTRITIS ( 87 patients )
COUGH ( 83 patients )
PHARYNGITIS ( 81 patients )
BRONCHITIS CHRONIC ( 67 patients )
ASTHMA ( 58 patients )
MYCOBACTERIAL INFECTION ( 49 patients )
GASTRIC ULCER ( 47 patients )
EAR INFECTION ( 45 patients )
ILL-DEFINED DISORDER ( 39 patients )
CHEST DISCOMFORT ( 39 patients )
BRONCHOPNEUMONIA ( 39 patients )
ACUTE SINUSITIS ( 37 patients )
OPPORTUNISTIC INFECTION PROPHYLAXIS ( 37 patients )
GASTRITIS ( 36 patients )
LUNG INFECTION ( 34 patients )
MYCOBACTERIUM ABSCESSUS INFECTION ( 33 patients )
INFLUENZA ( 29 patients )
TONSILLITIS ( 29 patients )
CELLULITIS ( 29 patients )
URINARY TRACT INFECTION ( 28 patients )
INFECTION PROPHYLAXIS ( 28 patients )
ANTIBIOTIC PROPHYLAXIS ( 28 patients )
CHRONIC OBSTRUCTIVE PULMONARY DISEASE ( 27 patients )
DUODENAL ULCER ( 26 patients )
CHRONIC SINUSITIS ( 25 patients )
BRONCHIOLITIS ( 24 patients )
BACTERIAL INFECTION ( 24 patients )
MYCOPLASMA INFECTION ( 23 patients )
PSEUDOMONAS INFECTION ( 23 patients )
TOOTH ABSCESS ( 23 patients )
BRONCHIECTASIS ( 23 patients )
PNEUMONIA MYCOPLASMAL ( 23 patients )
OSTEOMYELITIS ( 19 patients )
PRODUCTIVE COUGH ( 19 patients )
PNEUMONIA BACTERIAL ( 19 patients )
PNEUMONIA PRIMARY ATYPICAL ( 19 patients )
ISCHAEMIC ULCER ( 19 patients )
ANTIBIOTIC THERAPY ( 18 patients )
OROPHARYNGEAL PAIN ( 18 patients )
PNEUMOCYSTIS JIROVECI PNEUMONIA ( 18 patients )
PEPTIC ULCER ( 17 patients )
DIFFUSE PANBRONCHIOLITIS ( 17 patients )
OTITIS MEDIA ( 17 patients )
MALAISE ( 15 patients )
TUBERCULOSIS ( 15 patients )
PNEUMONIA LEGIONELLA ( 15 patients )
MYCOBACTERIUM FORTUITUM INFECTION ( 14 patients )
SKIN INFECTION ( 14 patients )
LYMPHADENOPATHY ( 13 patients )
MULTIPLE MYELOMA ( 13 patients )
DRUG EXPOSURE DURING PREGNANCY ( 13 patients )
BRONCHITIS ACUTE ( 12 patients )
EMPHYSEMA ( 12 patients )
INFLUENZA LIKE ILLNESS ( 12 patients )
GASTRIC ULCER HELICOBACTER ( 12 patients )
INFECTED SKIN ULCER ( 11 patients )
HIV INFECTION ( 11 patients )
HYPERTENSION ( 11 patients )
GASTROENTERITIS ( 10 patients )
RESPIRATORY DISORDER ( 10 patients )
PULMONARY EMBOLISM ( 10 patients )
GASTRITIS BACTERIAL ( 10 patients )
ULCER ( 10 patients )
INFLAMMATION ( 9 patients )
RHINITIS ALLERGIC ( 9 patients )
LUNG DISORDER ( 9 patients )
INTERSTITIAL LUNG DISEASE ( 9 patients )
GASTROENTERITIS HELICOBACTER ( 9 patients )
DYSPNOEA ( 9 patients )
HYPERPYREXIA ( 9 patients )
PNEUMONITIS ( 9 patients )
PULMONARY TUBERCULOSIS ( 9 patients )
EROSIVE DUODENITIS ( 9 patients )
MYCOBACTERIA TEST ( 9 patients )
PNEUMONIA CHLAMYDIAL ( 9 patients )
MATERNAL EXPOSURE TIMING UNSPECIFIED ( 8 patients )
CYSTITIS ( 8 patients )
MYCOBACTERIUM CHELONEI INFECTION ( 8 patients )
RHINORRHOEA ( 8 patients )
ACNE ( 8 patients )
SEPSIS ( 8 patients )
BRONCHOPULMONARY ASPERGILLOSIS ( 7 patients )
MYCOBACTERIUM MARINUM INFECTION ( 7 patients )
RHODOCOCCUS INFECTION ( 7 patients )
ERYSIPELAS ( 7 patients )
CROHN'S DISEASE ( 7 patients )
ATRIAL FIBRILLATION ( 7 patients )
RHINITIS ( 7 patients )
PHARYNGOLARYNGEAL PAIN ( 7 patients )
HEADACHE ( 7 patients )
CAMPYLOBACTER INFECTION ( 7 patients )
TUBERCULOSIS PROPHYLAXIS ( 7 patients )
GENERAL SYMPTOM ( 6 patients )
PNEUMONIA STREPTOCOCCAL ( 6 patients )
PHARYNGITIS STREPTOCOCCAL ( 6 patients )
OTITIS MEDIA ACUTE ( 6 patients )
PLEURISY ( 6 patients )
ACUTE TONSILLITIS ( 6 patients )
SINUS DISORDER ( 6 patients )
LYMPHADENITIS ( 5 patients )
ENTERITIS INFECTIOUS ( 5 patients )
CAMPYLOBACTER GASTROENTERITIS ( 5 patients )
BRONCHIAL DISORDER ( 5 patients )
LYME DISEASE ( 5 patients )
DENTAL OPERATION ( 5 patients )
LEGIONELLA INFECTION ( 5 patients )
GASTROOESOPHAGEAL REFLUX DISEASE ( 5 patients )
VAGINITIS BACTERIAL ( 5 patients )
CHRONIC RESPIRATORY FAILURE ( 5 patients )
TRACHEITIS ( 5 patients )
GASTROINTESTINAL INFECTION ( 5 patients )
RESPIRATORY TRACT INFECTION BACTERIAL ( 5 patients )
RHEUMATOID ARTHRITIS ( 4 patients )
LOBAR PNEUMONIA ( 4 patients )
BACTEROIDES INFECTION ( 4 patients )
COLLAPSE OF LUNG ( 4 patients )
RALES ( 4 patients )
HELICOBACTER PYLORI IDENTIFICATION TEST POSITIVE ( 4 patients )
SECRETION DISCHARGE ( 4 patients )
RESPIRATORY TRACT INFLAMMATION ( 4 patients )
DENTOFACIAL FUNCTIONAL DISORDER ( 4 patients )
MYOCARDIAL INFARCTION ( 4 patients )
PYELONEPHRITIS ( 4 patients )
INTENTIONAL OVERDOSE ( 4 patients )
METASTATIC RENAL CELL CARCINOMA ( 4 patients )
IDIOPATHIC THROMBOCYTOPENIC PURPURA ( 4 patients )
PLEURAL EFFUSION ( 4 patients )
STREPTOCOCCAL INFECTION ( 4 patients )
PELVIC PAIN ( 4 patients )
DRUG THERAPY ( 4 patients )
GASTROENTERITIS CRYPTOSPORIDIAL ( 4 patients )
INFECTED BITES ( 4 patients )
ANTIBACTERIAL PROPHYLAXIS ( 4 patients )
PULMONARY FIBROSIS ( 4 patients )
ORGANISING PNEUMONIA ( 3 patients )
GASTRIC INFECTION ( 3 patients )
SKIN ULCER ( 3 patients )
VIRAL INFECTION ( 3 patients )
BLISTER ( 3 patients )
HAEMOPHILUS INFECTION ( 3 patients )
POSTOPERATIVE WOUND INFECTION ( 3 patients )
DISSEMINATED TUBERCULOSIS ( 3 patients )
MITRAL VALVE PROLAPSE ( 3 patients )
GASTRITIS EROSIVE ( 3 patients )
PELVIC INFLAMMATORY DISEASE ( 3 patients )
ADENOIDITIS ( 3 patients )
HIATUS HERNIA ( 3 patients )
SICKLE CELL ANAEMIA WITH CRISIS ( 3 patients )
ATYPICAL MYCOBACTERIAL LYMPHADENITIS ( 3 patients )
DUODENITIS ( 3 patients )
OESOPHAGITIS ( 3 patients )
CHORIOAMNIONITIS ( 3 patients )
INFECTIOUS PLEURAL EFFUSION ( 3 patients )
MYCOBACTERIUM KANSASII INFECTION ( 3 patients )
PULMONARY GRANULOMA ( 3 patients )
ANTIINFLAMMATORY THERAPY ( 3 patients )
LOCALISED INFECTION ( 3 patients )
ENTERITIS ( 3 patients )
C-REACTIVE PROTEIN INCREASED ( 3 patients )
WALDENSTROM'S MACROGLOBULINAEMIA ( 3 patients )
BORRELIA BURGDORFERI SEROLOGY POSITIVE ( 3 patients )
COLITIS ( 3 patients )
ROSACEA ( 3 patients )
GASTRODUODENAL ULCER ( 3 patients )
PROTEUS TEST POSITIVE ( 3 patients )
PNEUMONIA ASPIRATION ( 3 patients )
RENAL TRANSPLANT ( 3 patients )
SUICIDE ATTEMPT ( 3 patients )
CYSTIC FIBROSIS ( 3 patients )
PERINEAL ABSCESS ( 3 patients )
LARYNGOTRACHEO BRONCHITIS ( 3 patients )
MYCOBACTERIUM CHELONAE INFECTION ( 3 patients )
CHLAMYDIAL INFECTION ( 3 patients )
TINNITUS ( 3 patients )
PHARYNGEAL INFLAMMATION ( 3 patients )
UREAPLASMA INFECTION ( 3 patients )
BACTERAEMIA ( 2 patients )
CHRONIC RESPIRATORY DISEASE ( 2 patients )
EMPYEMA ( 2 patients )
SPUTUM RETENTION ( 2 patients )
ARTHRITIS INFECTIVE ( 2 patients )
IDIOPATHIC PULMONARY FIBROSIS ( 2 patients )
PHARYNGOTONSILLITIS ( 2 patients )
PYLORIC STENOSIS ( 2 patients )
NERVOUS SYSTEM DISORDER ( 2 patients )
STEM CELL TRANSPLANT ( 2 patients )
SCARLET FEVER ( 2 patients )
IMMUNE TOLERANCE INDUCTION ( 2 patients )
NOCARDIOSIS ( 2 patients )
REFLUX OESOPHAGITIS ( 2 patients )
SUBCUTANEOUS NODULE ( 2 patients )
CEREBRAL TOXOPLASMOSIS ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
SUPERINFECTION ( 2 patients )

Drugs with high FDA adverse event association with DUODENAL PERFORATION:

FLUOROURACIL (54 patients)
AVASTIN (44 patients)
OXALIPLATIN (37 patients)
DECADRON (26 patients)
LOPERAMIDE (25 patients)
PREDNISOLONE (21 patients)
OMEPRAZOLE (21 patients)
ELPLAT (19 patients)
CAPECITABINE (19 patients)
ONDANSETRON (18 patients)
VOLTAREN (18 patients)
CITALOPRAM HYDROBROMIDE (17 patients)
LEUCOVORIN CALCIUM (16 patients)
LOXONIN (16 patients)
ACETAMINOPHEN (15 patients)
OXYCONTIN (15 patients)
BEVACIZUMAB (15 patients)
CISPLATIN (15 patients)
FAMOTIDINE (14 patients)
HUMIRA (14 patients)
CALCIUM LEVOFOLINATE (13 patients)
MAXOLON (13 patients)
GEMZAR (13 patients)
MUCOSTA (12 patients)
ASPIRIN (12 patients)
NITRAZEPAM (11 patients)
ACTEMRA (11 patients)
PARACETAMOL (11 patients)
DEXAMETHASONE (11 patients)
LASIX (10 patients)
URAL (10 patients)
METOCLOPRAMIDE (10 patients)
NEXAVAR (10 patients)
LIPITOR (9 patients)
OLANZAPINE (9 patients)
KYTRIL (9 patients)
FENTANYL (9 patients)
BETAMETHASONE (9 patients)
PROGRAF (9 patients)
PREDONINE (9 patients)
ZOMETA (8 patients)
VIOXX (8 patients)
AVONEX (8 patients)
ENDONE (8 patients)
SUTENT (8 patients)
CARBOPLATIN (8 patients)
MUCODYNE (8 patients)
NAPROXEN (8 patients)
FOLIC ACID (8 patients)
DIANEAL (8 patients)
SOLU-MEDROL (7 patients)
PREDNISONE (7 patients)
IRINOTECAN HCL (7 patients)
ARICEPT (7 patients)
TEMAZEPAM (7 patients)
MORPHINE SULFATE (7 patients)
TAXOL (7 patients)
VITAMIN D (7 patients)
FOSAMAX (7 patients)
POTASSIUM CHLORIDE (7 patients)
LANSOPRAZOLE (7 patients)
5-FU (6 patients)
ROPION (6 patients)
FERROUS FUMARATE (6 patients)
AMIKACIN SULFATE (6 patients)
IRESSA (6 patients)
ERBITUX (6 patients)
METOPROLOL (6 patients)
VICODIN (6 patients)
TEMSIROLIMUS (6 patients)
MAGMITT (6 patients)
MORPHINE (6 patients)
MOBIC (6 patients)
FORTEO (6 patients)
DIOVAN (6 patients)
ZYLORIC (6 patients)
ALBUMIN (HUMAN) (5 patients)
GLIBENCLAMIDE (5 patients)
AMPICILLIN (5 patients)
TAXOTERE (5 patients)
PRAVASTATIN (5 patients)
CALCIUM (5 patients)
SIMVASTATIN (5 patients)
TASIGNA (5 patients)
URSO 250 (5 patients)
RULID (ROXITHROMYCIN) (5 patients)
XELODA (5 patients)
MELOXICAM (5 patients)
MYCOPHENOLATE MOFETIL (5 patients)
CODEINE SULFATE (5 patients)
NATEGLINIDE (5 patients)
FENTANYL CITRATE (5 patients)
PARAPLATIN (5 patients)
CYCLOPHOSPHAMIDE (5 patients)
RADIATION THERAPY (5 patients)
DIGOXIN (5 patients)
PROTONIX (4 patients)
TRANSAMIN (TRANEXAMIC ACID) (4 patients)
METOPROLOL TARTRATE (4 patients)
ADONA (CARBAZOCHROME SODIUM SULFONATE) (4 patients)
ADRIAMYCIN PFS (4 patients)
ZOFRAN (4 patients)
LIVALO (4 patients)
ALLOPURINOL (4 patients)
TARCEVA (4 patients)
EMEND (4 patients)
METRONIDAZOLE (4 patients)
ASA (4 patients)
ATIVAN (4 patients)
VINCRISTINE (4 patients)
VANCOMYCIN HYDROCHLORIDE (4 patients)
EFUDEX (4 patients)
LOXOPROFEN (4 patients)
BETAMIPRON + PANIPENEM (4 patients)
PACLITAXEL (4 patients)
BUPRENORPHINE HYDROCHLORIDE (4 patients)
CABAZITAXEL (4 patients)
FOSRENOL (4 patients)
CALBLOCK (4 patients)
LEFTOSE (4 patients)
LEVOFOLINATE (4 patients)
CARTEOLOL HYDROCHLORIDE (4 patients)
CEFTAZIDIME (4 patients)
LYRICA (4 patients)
METFORMIN HCL (4 patients)
CINAL (CINAL) (4 patients)
CIPROFLOXACIN (4 patients)
FERROMIA (FERROUS CITRATE) (4 patients)
CLARITHROMYCIN (4 patients)
CLOPIDOGREL BISULFATE (4 patients)
NAIXAN (NAPROXEN SODIUM) (4 patients)
GEMCITABINE (4 patients)
ONDANSERTRON HCL (4 patients)
GASMOTIN (4 patients)
COUMADIN (4 patients)
PANTOSIN (BENZYL ALCOHOL, PANTETHINE) (4 patients)
INDAPAMIDE (4 patients)
PLAVIX (4 patients)
PENTAZOCINE LACTATE (4 patients)
WARFARIN SODIUM (4 patients)
PREDNISONE TAB (4 patients)
DEXART (4 patients)
KETOPROFEN (4 patients)
DICLOFENAC SODIUM (4 patients)
SELBEX (TEPRENONE) (4 patients)
SODIUM BICARBONATE (4 patients)
SENOKOT (4 patients)
INSULIN (4 patients)
DOBUTAMINE HYDROCHLORIDE + DOPAMINE HYDROCHLORIDE (4 patients)
INDOMETHACIN SODIUM (4 patients)
SULFAMETHOXAZOLE + TRIMETHOPRIM (4 patients)
ADALAT (3 patients)
NIFEDIPINE (3 patients)
ENOXOLONE/HYALURONATE SODIUM/POLYVIDONE (3 patients)
ALDARA (3 patients)
PEPCID (3 patients)
SOLITA-T3 (3 patients)
EXJADE (3 patients)
MIRALAX (3 patients)
AMLODIPINE BESYLATE (3 patients)
HYPEN (3 patients)
GLAKAY (3 patients)
PREVACID (3 patients)
RANITIDINE (3 patients)
SPIRONOLACTONE (3 patients)
ARTIST (3 patients)
ATENOLOL (3 patients)
FLAGYL (3 patients)
NASEA (3 patients)
MEYLON (3 patients)
INDISETRON HYDROCHLORIDE (3 patients)
NEXIUM (3 patients)
OLMETEC (3 patients)
NYSTATIN (3 patients)
IMOVANE (3 patients)
CALCIUM CARBONATE (3 patients)
PRILOSEC (3 patients)
ISOVORIN (3 patients)
CALONAL (3 patients)
CALONAL (ACETAMINOPHEN) (3 patients)
SULPERAZON (3 patients)
LEVOTHYROXINE SODIUM (3 patients)
CARMELLOSE (3 patients)
CARVEDILOL (3 patients)
LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE (3 patients)
LORAZEPAM (3 patients)
CELECOXIB (3 patients)
METFORMIN (3 patients)
ERLOTINIB HYDROCHLORIDE (3 patients)
ENALAPRIL MALEATE (3 patients)
FLUCONAZOLE (3 patients)
FLUVOXAMINE MALEATE (3 patients)
CLOZARIL (3 patients)
CODEINE PHOSPHATE (3 patients)
ESOMEPRAZOLE MAGNESIUM (3 patients)
GASTER D (3 patients)
GLYBURIDE (3 patients)
CYCLOSPORINE (3 patients)
OMEPRA (3 patients)
DACLIZUMAB (3 patients)
DAI-KENCHU-TO (3 patients)
IBUPROFEN (3 patients)
HYZAAR (3 patients)
PREDNISONE / METHOTREXATE (3 patients)
REBAMIPIDE (REBAMIPIDE) (3 patients)
DICLOFENAC (DICLOFENAC) (3 patients)
ROPIVACAINE (3 patients)
RENIVACE (3 patients)
DILTIAZEM (3 patients)
SHAKUYAKU-KANZO-TO (3 patients)

Most common side effects for patients taking CLARITHROMYCIN:

DRUG INTERACTION (1440 patients)
PYREXIA (897 patients)
DYSPNOEA (628 patients)
DIARRHOEA (610 patients)
VOMITING (558 patients)
NAUSEA (538 patients)
PNEUMONIA (536 patients)
RENAL FAILURE ACUTE (470 patients)
RHABDOMYOLYSIS (399 patients)
RASH (363 patients)
ALANINE AMINOTRANSFERASE INCREASED (345 patients)
MALAISE (343 patients)
DIZZINESS (336 patients)
CONFUSIONAL STATE (334 patients)
COUGH (329 patients)
ASTHENIA (308 patients)
ANAEMIA (299 patients)
ABDOMINAL PAIN (297 patients)
PAIN (295 patients)
HYPOTENSION (287 patients)
HEADACHE (281 patients)
MYALGIA (263 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (261 patients)
DEHYDRATION (256 patients)
RESPIRATORY FAILURE (256 patients)
HEPATIC FUNCTION ABNORMAL (254 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (250 patients)
INTERSTITIAL LUNG DISEASE (242 patients)
PRURITUS (239 patients)
SEPSIS (238 patients)
THROMBOCYTOPENIA (234 patients)
ANXIETY (232 patients)
OEDEMA PERIPHERAL (229 patients)
LIVER DISORDER (228 patients)
PLEURAL EFFUSION (223 patients)
CONDITION AGGRAVATED (222 patients)
ERYTHEMA (212 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (211 patients)
RENAL IMPAIRMENT (210 patients)
HAEMOGLOBIN DECREASED (208 patients)
TACHYCARDIA (208 patients)
PANCYTOPENIA (206 patients)
LIVER FUNCTION TEST ABNORMAL (205 patients)
DRUG INEFFECTIVE (202 patients)
BLOOD CREATININE INCREASED (201 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (200 patients)
PLATELET COUNT DECREASED (200 patients)
WEIGHT DECREASED (199 patients)
CONVULSION (186 patients)
FATIGUE (185 patients)
WHITE BLOOD CELL COUNT DECREASED (183 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (179 patients)
DECREASED APPETITE (179 patients)
C-REACTIVE PROTEIN INCREASED (175 patients)
RENAL FAILURE (175 patients)
AGITATION (174 patients)
FALL (172 patients)
ATRIAL FIBRILLATION (170 patients)
MUSCULAR WEAKNESS (169 patients)
MULTI-ORGAN FAILURE (166 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (165 patients)
DRUG ERUPTION (165 patients)
PAIN IN EXTREMITY (164 patients)
SOMNOLENCE (159 patients)
JAUNDICE (158 patients)
LOWER RESPIRATORY TRACT INFECTION (155 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (151 patients)
PULMONARY EMBOLISM (150 patients)
STEVENS-JOHNSON SYNDROME (149 patients)
INSOMNIA (148 patients)
HEART RATE INCREASED (147 patients)
ARTHRALGIA (146 patients)
HYPOGLYCAEMIA (146 patients)
ABDOMINAL PAIN UPPER (144 patients)
LOSS OF CONSCIOUSNESS (144 patients)
HYPERTENSION (142 patients)
NEUTROPENIA (141 patients)
BRONCHITIS (139 patients)
PALPITATIONS (138 patients)
DYSGEUSIA (135 patients)
DRUG TOXICITY (134 patients)
BLOOD BILIRUBIN INCREASED (132 patients)
AGRANULOCYTOSIS (131 patients)
HALLUCINATION (129 patients)
CHEST PAIN (128 patients)
TREMOR (128 patients)
CARDIAC FAILURE (126 patients)
ANOREXIA (125 patients)
HYPERSENSITIVITY (124 patients)
CONSTIPATION (124 patients)
INFECTION (123 patients)
DELIRIUM (123 patients)
BACK PAIN (123 patients)
ERYTHEMA MULTIFORME (122 patients)
WHITE BLOOD CELL COUNT INCREASED (121 patients)
PSEUDOMEMBRANOUS COLITIS (120 patients)
PERICARDIAL EFFUSION (119 patients)
HYPERHIDROSIS (119 patients)
HYPOXIA (119 patients)
BRADYCARDIA (118 patients)
ASTHMA (118 patients)
ABNORMAL BEHAVIOUR (116 patients)
HEPATIC FAILURE (116 patients)
MYOSITIS (116 patients)
CARDIAC ARREST (113 patients)
DEPRESSION (112 patients)
BLOOD PRESSURE DECREASED (110 patients)
HYPONATRAEMIA (109 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (109 patients)
METABOLIC ACIDOSIS (107 patients)
MYOPATHY (107 patients)
NASOPHARYNGITIS (106 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (106 patients)
INJURY (105 patients)
DEATH (104 patients)
URTICARIA (104 patients)
PRODUCTIVE COUGH (103 patients)
HYPOKALAEMIA (102 patients)
URINARY TRACT INFECTION (102 patients)
SHOCK (100 patients)
DRUG LEVEL INCREASED (100 patients)
DYSPHAGIA (100 patients)
DRUG HYPERSENSITIVITY (100 patients)
CHILLS (99 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (97 patients)
GAIT DISTURBANCE (96 patients)
BLOOD PRESSURE INCREASED (94 patients)
SEPTIC SHOCK (92 patients)
TOXICITY TO VARIOUS AGENTS (92 patients)
MELAENA (92 patients)
TOXIC EPIDERMAL NECROLYSIS (91 patients)
PARAESTHESIA (90 patients)
OROPHARYNGEAL PAIN (90 patients)
ELECTROCARDIOGRAM QT PROLONGED (89 patients)
STOMATITIS (88 patients)
URINARY RETENTION (88 patients)
ARRHYTHMIA (88 patients)
INFLAMMATION (88 patients)
BLOOD UREA INCREASED (87 patients)
IMMUNE RECONSTITUTION SYNDROME (86 patients)
MYOCARDIAL INFARCTION (86 patients)
INFLUENZA (84 patients)
DRY MOUTH (84 patients)
CLOSTRIDIUM DIFFICILE COLITIS (83 patients)
RASH MACULO-PAPULAR (83 patients)
TUBULOINTERSTITIAL NEPHRITIS (83 patients)
GASTROINTESTINAL HAEMORRHAGE (83 patients)
SINUSITIS (82 patients)
HYPOAESTHESIA (82 patients)
FEELING ABNORMAL (82 patients)
CARDIO-RESPIRATORY ARREST (82 patients)
NEUTROPHIL COUNT DECREASED (82 patients)
DYSPEPSIA (79 patients)
SYNCOPE (78 patients)
GASTRIC ULCER (77 patients)
DIABETES MELLITUS (76 patients)
HAEMATURIA (76 patients)
OXYGEN SATURATION DECREASED (76 patients)
EMOTIONAL DISTRESS (74 patients)
VANISHING BILE DUCT SYNDROME (74 patients)
VISION BLURRED (74 patients)
BONE MARROW FAILURE (74 patients)
CONTUSION (73 patients)
HYPERGLYCAEMIA (73 patients)
DEEP VEIN THROMBOSIS (72 patients)
RESPIRATORY ARREST (71 patients)
GOUT (71 patients)
ACUTE HEPATIC FAILURE (71 patients)
SWOLLEN TONGUE (71 patients)
ANGIOEDEMA (71 patients)
TORSADE DE POINTES (70 patients)
DRUG EXPOSURE DURING PREGNANCY (70 patients)
WHEEZING (70 patients)
VIRAL INFECTION (70 patients)
BLISTER (70 patients)
CHOLELITHIASIS (70 patients)
HAEMODIALYSIS (69 patients)
RASH GENERALISED (69 patients)
OSTEOMYELITIS (69 patients)
SPEECH DISORDER (69 patients)
LETHARGY (68 patients)
DISEASE PROGRESSION (68 patients)
EOSINOPHILIA (68 patients)
EPISTAXIS (68 patients)
ABDOMINAL DISTENSION (67 patients)
HYPERLIPIDAEMIA (67 patients)
OEDEMA (67 patients)
CHOLESTASIS (67 patients)
HELICOBACTER INFECTION (66 patients)
ATYPICAL MYCOBACTERIAL INFECTION (66 patients)
SUPRAVENTRICULAR TACHYCARDIA (66 patients)
RESPIRATORY DISORDER (66 patients)
HAEMOPTYSIS (65 patients)
HYPERKALAEMIA (65 patients)
LUNG DISORDER (65 patients)
LEUKOPENIA (65 patients)
OVERDOSE (64 patients)
TOXIC SKIN ERUPTION (64 patients)
ACUTE RESPIRATORY DISTRESS SYNDROME (64 patients)
HEPATOTOXICITY (63 patients)
GASTRITIS (62 patients)
BLOOD TRIGLYCERIDES INCREASED (61 patients)
ENCEPHALOPATHY (61 patients)
CHEST DISCOMFORT (61 patients)
HAEMOLYTIC ANAEMIA (61 patients)
HEPATITIS (61 patients)
BACTERIAL INFECTION (61 patients)
OSTEONECROSIS OF JAW (61 patients)
HERPES ZOSTER (61 patients)
NEUROPATHY PERIPHERAL (60 patients)

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Recent FactMed Activity for CLARITHROMYCIN

Issue	Description / Topic	Timestamp
QUESTION DRUG INTERACTION	Aerius 2.5mg with 3.5 hrs apart taking with panadol cold and flu 1000mg is it okay?	2015-02-24 01:11:10
QUESTION FLUSHING	I've experienced mild flushing with clarithromycin. It started with the 4th dose. It now seems to be subsiding, just a little redness on my cheeks. Can I complete the course of the medicine?	2015-03-07 22:04:37
QUESTION AGEUSIA	Could there be a relationship between Infectious mononucleosis, clarithromycin and ageusia? Can someone help? My 18 year old son initially diagnosed with tonsillitis took cephalexin then clarithromycin for 9 days before being diagnosed with infectious mononucleosis. He was very very sick. At the end of week 2 of (IM) he was hospitalised for 5 days to manage pain (throat), fluids and monitor his splenomegaly (diagnosed via palpating and abdominal US) and abnormal liver function. He returned home in week 3, during which he developed a significant body rash worse on the torso and on the limbs proximally, his physician believes as a result of the interaction between the virus and the antibiotics. After 7 days the rash had virtually disappeared but over a few hours he then developed ageusia, initially he complained of a metallic taste but that disappeared over a few days. It is now 16 days after developing ageusia, with no change in his ability to taste yet. He has no other symptoms, and appears to be making a good recovery from IM otherwise. Can someone help? He is only 18 and is quite distressed by this. Thank you.	2015-04-06 02:39:29
CONCERN MIGRAINE	I had one claritek(CLARITHROMYCIN) 250mg today which ended up in the worst migraine i have ever had. Just wanted to inform	2015-08-20 15:50:01
QUESTION TESTICULAR PAIN	I developed testicular pain after taking clarithromycin and at a later date I took the drug again which made my pain worse again. The pain stays but not as bad after finishing the antibiotics	2015-10-11 15:02:42
QUESTION DRUG INTERACTION	Can Ixprim and Clarithromycin be taken together?	2015-12-12 08:08:51
CONCERN AGGRESSION	My husband of 16 years I've always been so loving sweet and delicate is now very aggressive For the past five days which is when he was put on this medication It has made my life A living nightmare will this pass or will he remain like this it's horrible	2016-02-21 20:23:08
QUESTION VITAMIN B12 DEFICIENCY	I had amoxicillin first, then two courses of clarithromycin for a lower respiratory tract infection, I am clear of the infection, my chest X-ray came back normal, but I am feeling tired, weak, legs feel like jelly on waking up and sometimes feel like I am going to pass out.	2016-02-27 12:58:10
QUESTION DRUG INTERACTION	Are you able to take Claritin when taking Depakote,propananolol,risperdal,Effexor,fluphenzine,buspar, lisinopril,trazodone	2016-03-12 21:40:20
QUESTION GUILLAIN-BARRE SYNDROME	I have a brother who is suffering from acute, severe Gullain Barre Syndrome immediately after taking clarithromycin. His treating doctors are very dismissive of it being a drug reaction and have asked for the specific resources that we have presented. Can you tell me where I can find the FDA source to present them with?	2016-09-15 10:23:00
QUESTION PHOTOSENSITIVITY ALLERGIC REACTION	I developed sun burn on my face whilst taking Clarithromycen and my doctor stated it was due to Photosensitivity and to avoid direct sun shine. I have since completed my prescribed course and seven days later, after only minimal sun exposure, now have a fully sun burnt face - very itchy, hot and redness on face only. Not on arms - the only other exposed area. Is this the effect of the drug in my system even one week after completion of course???	2016-12-05 19:42:33
QUESTION ATRIAL FIBRILLATION	I am a 75 year old lady suffering from AF for a number of years. I am on a course of Clarithromycin* for a sinus infection. Would this medication* cause an AF event? I take 3 blood pressure tabs..BP at present is 126/65. thank you. Mrs Beryl Davis	2016-12-07 05:16:11
QUESTION DRUG INTERACTION	Hello, I am on Day 5 of 8 days taking Biclar Uno 500 for a sinus infection. All along I have had a terrible, metallic taste in my mouth and my stomach has been...really gurgly, for lack of a more medical term. Today I have diarrhea and I'm wondering if it is an llaergic reaction to the antibiotic. Is this a common side effect?	2017-02-05 03:59:32
QUESTION NEURALGIA	I was prescribed 500mg Clarithromycin bds last week after having an unpleasant ?flu virus for over a week. I'm 80yrs old. I had a number of unpleasant effects - headache, unpleasant taste in my mouth, unable to sleep etc. I phoned the GP to say I wasn't completing the course although only half way through (3 days). I'm still experiencing unpleasant neuralgia in the left side of my face - from my t.m.joint tracking the jaw line and into my teeth. I had a large L. back tooth filled a few weeks ago with an injection but the dentist xrayed and he says no problems there. Do you think my ?trigeminal neuralgia could be caused by clarithromycin and what is the best way to deal with it? Thank you.	2017-02-13 07:08:06
QUESTION CONSTIPATION	I cannot do poo since starting Clorom XL 500mg.....please advise.	2017-02-20 14:24:52
QUESTION HIATUS HERNIA	I have a hiatus hernia which was manageable until taking the drug Clarithromycen for Strep B in October 2016. Now my acid volumes have increased to unbearable levels. They have not settled despite taking more drugs to ease it. I am now seeking help with this problem, even considering surgery. I am really miserable with the pain.	2017-05-25 07:47:00

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