Is INTERVERTEBRAL DISC DEGENERATION a side effect of CYCLOSPORINE ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of CYCLOSPORINE patients who developed INTERVERTEBRAL DISC DEGENERATION.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 11 individuals taking CYCLOSPORINE reported INTERVERTEBRAL DISC DEGENERATION to the FDA. A total of 23141 CYCLOSPORINE drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between CYCLOSPORINE and INTERVERTEBRAL DISC DEGENERATION. In doing so, we compare CYCLOSPORINE with other drugs that cause INTERVERTEBRAL DISC DEGENERATION, to help you evaluate whether or not CYCLOSPORINE causes INTERVERTEBRAL DISC DEGENERATION. Likewise, this page shows the most highly-reported side effects of CYCLOSPORINE, so you can see if INTERVERTEBRAL DISC DEGENERATION ranks among CYCLOSPORINE's most well-known side effects.

Summary Statistics
Reports of CYCLOSPORINE causing INTERVERTEBRAL DISC DEGENERATION: 11
Reports of any side effect of CYCLOSPORINE : 23141
Percentage of CYCLOSPORINE patients where INTERVERTEBRAL DISC DEGENERATION is a reported side effect: 0.0475%

FDA reports of any drug causing INTERVERTEBRAL DISC DEGENERATION : 7118
Average percentage for all medicated patients where INTERVERTEBRAL DISC DEGENERATION is reported as a complication: 0.0446%

Physician opinion on CYCLOSPORINE as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing CYCLOSPORINE:

RENAL TRANSPLANT ( 1844 patients )
PROPHYLAXIS AGAINST GRAFT VERSUS HOST DISEASE ( 1717 patients )
IMMUNOSUPPRESSION ( 1165 patients )
STEM CELL TRANSPLANT ( 793 patients )
PROPHYLAXIS AGAINST TRANSPLANT REJECTION ( 638 patients )
APLASTIC ANAEMIA ( 503 patients )
LIVER TRANSPLANT ( 494 patients )
DRUG USE FOR UNKNOWN INDICATION ( 395 patients )
BONE MARROW TRANSPLANT ( 379 patients )
HEART TRANSPLANT ( 370 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 350 patients )
IMMUNOSUPPRESSANT DRUG THERAPY ( 342 patients )
PSORIASIS ( 334 patients )
NEPHROTIC SYNDROME ( 274 patients )
CORD BLOOD TRANSPLANT THERAPY ( 254 patients )
GRAFT VERSUS HOST DISEASE ( 237 patients )
LUNG TRANSPLANT ( 233 patients )
RHEUMATOID ARTHRITIS ( 203 patients )
INTERSTITIAL LUNG DISEASE ( 123 patients )
PROPHYLAXIS ( 117 patients )
BEHCET'S SYNDROME ( 107 patients )
HISTIOCYTOSIS HAEMATOPHAGIC ( 90 patients )
SYSTEMIC LUPUS ERYTHEMATOSUS ( 85 patients )
COLITIS ULCERATIVE ( 85 patients )
PUSTULAR PSORIASIS ( 80 patients )
DERMATOMYOSITIS ( 67 patients )
ALLOGENIC BONE MARROW TRANSPLANTATION THERAPY ( 65 patients )
MYELODYSPLASTIC SYNDROME ( 64 patients )
PSORIATIC ARTHROPATHY ( 58 patients )
CHRONIC GRAFT VERSUS HOST DISEASE ( 53 patients )
APLASIA PURE RED CELL ( 49 patients )
GLOMERULONEPHRITIS MEMBRANOUS ( 45 patients )
TRANSPLANT ( 45 patients )
DERMATITIS ATOPIC ( 44 patients )
JUVENILE ARTHRITIS ( 43 patients )
PYODERMA GANGRENOSUM ( 41 patients )
ACUTE MYELOID LEUKAEMIA ( 40 patients )
ORGAN TRANSPLANT ( 39 patients )
DRY EYE ( 38 patients )
IDIOPATHIC THROMBOCYTOPENIC PURPURA ( 37 patients )
UVEITIS ( 35 patients )
EVANS SYNDROME ( 34 patients )
ACUTE GRAFT VERSUS HOST DISEASE ( 32 patients )
ILL-DEFINED DISORDER ( 31 patients )
TRANSPLANT REJECTION ( 30 patients )
POLYMYOSITIS ( 29 patients )
LYMPHOHISTIOCYTOSIS ( 28 patients )
HEART AND LUNG TRANSPLANT ( 27 patients )
WEGENER'S GRANULOMATOSIS ( 25 patients )
BONE MARROW FAILURE ( 25 patients )
CHRONIC LYMPHOCYTIC LEUKAEMIA ( 24 patients )
PEMPHIGUS ( 23 patients )
FOCAL SEGMENTAL GLOMERULOSCLEROSIS ( 23 patients )
MULTIPLE MYELOMA ( 22 patients )
SJOGREN'S SYNDROME ( 22 patients )
ECZEMA ( 21 patients )
PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA ( 21 patients )
BONE MARROW CONDITIONING REGIMEN ( 21 patients )
LUPUS NEPHRITIS ( 21 patients )
MYASTHENIA GRAVIS ( 21 patients )
AUTOIMMUNE HEPATITIS ( 18 patients )
KIDNEY TRANSPLANT REJECTION ( 17 patients )
ANGIOIMMUNOBLASTIC T-CELL LYMPHOMA ( 17 patients )
PEMPHIGOID ( 17 patients )
STILL'S DISEASE ADULT ONSET ( 16 patients )
UNRELATED DONOR BONE MARROW TRANSPLANTATION THERAPY ( 15 patients )
ANAEMIA HAEMOLYTIC AUTOIMMUNE ( 14 patients )
CROHN'S DISEASE ( 14 patients )
PROTEINURIA ( 14 patients )
EYE DISORDER ( 13 patients )
CONJUNCTIVITIS ( 10 patients )
ALOPECIA UNIVERSALIS ( 10 patients )
EPSTEIN-BARR VIRUS INFECTION ( 10 patients )
SKIN LESION ( 10 patients )
RETINOBLASTOMA BILATERAL ( 9 patients )
CORNEAL TRANSPLANT ( 9 patients )
RENAL AND PANCREAS TRANSPLANT ( 9 patients )
LEUKAEMIA ( 9 patients )
ERYTHRODERMIC PSORIASIS ( 9 patients )
LUPUS PNEUMONITIS ( 9 patients )
GLOMERULONEPHRITIS MEMBRANOPROLIFERATIVE ( 9 patients )
NEURODERMATITIS ( 8 patients )
FOCAL GLOMERULOSCLEROSIS ( 8 patients )
ACUTE LYMPHOCYTIC LEUKAEMIA ( 8 patients )
ARTHRITIS ( 8 patients )
RENAL AND LIVER TRANSPLANT ( 8 patients )
HEPATITIS B ( 7 patients )
TOXIC EPIDERMAL NECROLYSIS ( 7 patients )
ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODY POSITIVE VASCULITIS ( 7 patients )
CONGENITAL APLASTIC ANAEMIA ( 7 patients )
GLOMERULONEPHRITIS MINIMAL LESION ( 7 patients )
THROMBOCYTOPENIA ( 6 patients )
VASCULITIS ( 6 patients )
IMPETIGO HERPETIFORMIS ( 6 patients )
PARANEOPLASTIC SYNDROME ( 6 patients )
SYMPATHETIC OPHTHALMIA ( 6 patients )
KERATOPLASTY ( 6 patients )
LANGERHANS' CELL GRANULOMATOSIS ( 6 patients )
RENAL DISORDER ( 6 patients )
LARGE GRANULAR LYMPHOCYTOSIS ( 6 patients )
LYMPHOMA ( 6 patients )
PARANEOPLASTIC PEMPHIGUS ( 6 patients )
DERMATITIS EXFOLIATIVE ( 5 patients )
CHRONIC LYMPHOCYTIC LEUKAEMIA REFRACTORY ( 5 patients )
PITYRIASIS RUBRA PILARIS ( 5 patients )
HISTOPLASMOSIS ( 5 patients )
LANGERHANS' CELL HISTIOCYTOSIS ( 5 patients )
LYMPHOCYTIC LEUKAEMIA ( 5 patients )
POLYCHONDRITIS ( 5 patients )
INFLAMMATORY BOWEL DISEASE ( 5 patients )
LICHEN SCLEROSUS ( 5 patients )
RETINOBLASTOMA ( 5 patients )
SYSTEMIC SCLEROSIS ( 5 patients )
SECONDARY IMMUNODEFICIENCY ( 5 patients )
MYOSITIS ( 5 patients )
THROMBOTIC THROMBOCYTOPENIC PURPURA ( 5 patients )
INFECTION PROPHYLAXIS ( 5 patients )
HEPATIC FUNCTION ABNORMAL ( 4 patients )
SARCOIDOSIS ( 4 patients )
FOETAL EXPOSURE DURING PREGNANCY ( 4 patients )
ACUTE GRAFT VERSUS HOST DISEASE IN LIVER ( 4 patients )
DRUG EXPOSURE DURING PREGNANCY ( 4 patients )
CHOROIDITIS ( 4 patients )
CONJUNCTIVOPLASTY ( 4 patients )
NODULAR VASCULITIS ( 4 patients )
HIDRADENITIS ( 4 patients )
MICROSCOPIC POLYANGIITIS ( 4 patients )
ACUTE FEBRILE NEUTROPHILIC DERMATOSIS ( 4 patients )
BREAST CANCER ( 4 patients )
HAEMATOLOGICAL MALIGNANCY ( 4 patients )
COLITIS ( 4 patients )
ACUTE GRAFT VERSUS HOST DISEASE IN INTESTINE ( 4 patients )
HAEMOLYTIC ANAEMIA ( 4 patients )
ACUTE GRAFT VERSUS HOST DISEASE IN SKIN ( 4 patients )
MUSCULAR WEAKNESS ( 4 patients )
CYSTIC FIBROSIS ( 4 patients )
ANTIPHOSPHOLIPID SYNDROME ( 3 patients )
TUBERCULOID LEPROSY ( 3 patients )
IDIOPATHIC PULMONARY FIBROSIS ( 3 patients )
APLASIA ( 3 patients )
IMMUNE SYSTEM DISORDER ( 3 patients )
TAKAYASU'S ARTERITIS ( 3 patients )
KERATOCONJUNCTIVITIS SICCA ( 3 patients )
EPSTEIN-BARR VIRUS ASSOCIATED LYMPHOPROLIFERATIVE DISORDER ( 3 patients )
ASTHMA ( 3 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 3 patients )
BRONCHITIS ( 3 patients )
THROMBOTIC MICROANGIOPATHY ( 3 patients )
ANKYLOSING SPONDYLITIS ( 3 patients )
CARDIAC DISORDER ( 3 patients )
NEPHRITIS ( 3 patients )
MACULAR DEGENERATION ( 3 patients )
STEVENS-JOHNSON SYNDROME ( 3 patients )
IRON OVERLOAD ( 3 patients )
MALIGNANT HISTIOCYTOSIS ( 3 patients )
CHRONIC GRAFT VERSUS HOST DISEASE IN SKIN ( 3 patients )
DERMATITIS CONTACT ( 3 patients )
MATERNAL EXPOSURE TIMING UNSPECIFIED ( 3 patients )
ALPORT'S SYNDROME ( 3 patients )
RASH ( 3 patients )
OBLITERATIVE BRONCHIOLITIS ( 3 patients )
ANAEMIA ( 3 patients )
DIFFUSE ALVEOLAR DAMAGE ( 3 patients )
GASTROINTESTINAL INFLAMMATION ( 3 patients )
IMMUNOMODULATORY THERAPY ( 3 patients )
THROMBOCYTOPENIC PURPURA ( 3 patients )
DIFFUSE VASCULITIS ( 3 patients )
BRONCHOPULMONARY ASPERGILLOSIS ALLERGIC ( 3 patients )
PANCREAS TRANSPLANT ( 3 patients )
ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA ( 3 patients )
BURKITT'S LYMPHOMA ( 3 patients )
CRYOGLOBULINAEMIA ( 3 patients )
THYMOMA ( 3 patients )
HYPER IGD SYNDROME ( 3 patients )
PANCYTOPENIA ( 3 patients )
WISKOTT-ALDRICH SYNDROME ( 3 patients )
HEART TRANSPLANT REJECTION ( 3 patients )
XANTHOGRANULOMA ( 3 patients )
CYTOMEGALOVIRUS COLITIS ( 2 patients )
RETINAL VASCULITIS ( 2 patients )
GLOMERULONEPHRITIS RAPIDLY PROGRESSIVE ( 2 patients )
BLASTOMYCOSIS ( 2 patients )
GLOMERULOSCLEROSIS ( 2 patients )
ILEUS ( 2 patients )
NON-HODGKIN'S LYMPHOMA ( 2 patients )
EPIDERMOLYSIS BULLOSA ( 2 patients )
HEPATITIS E ( 2 patients )
SCLERODERMA ( 2 patients )
URTICARIA CHRONIC ( 2 patients )
GLAUCOMA ( 2 patients )
MIXED CONNECTIVE TISSUE DISEASE ( 2 patients )
ERDHEIM-CHESTER DISEASE ( 2 patients )
GLOMERULONEPHRITIS ( 2 patients )
NEOPLASM ( 2 patients )
POEMS SYNDROME ( 2 patients )
RENAL FAILURE ( 2 patients )
COMBINED IMMUNODEFICIENCY ( 2 patients )
MULTIPLE-DRUG RESISTANCE ( 2 patients )
PANCREATIC CARCINOMA METASTATIC ( 2 patients )
CUTANEOUS SARCOIDOSIS ( 2 patients )
INFECTION ( 2 patients )
COMPLICATIONS OF TRANSPLANT SURGERY ( 2 patients )
PANNICULITIS ( 2 patients )
EYE INFECTION ( 2 patients )
CONGENITAL WHITE BLOOD CELL DISORDER ( 2 patients )
HYPERTENSION ( 2 patients )
HEPATIC CIRRHOSIS ( 2 patients )
MYELITIS ( 2 patients )
HEPATIC NEOPLASM MALIGNANT ( 2 patients )
PREMEDICATION ( 2 patients )

Drugs with high FDA adverse event association with INTERVERTEBRAL DISC DEGENERATION:

FOSAMAX (6026 patients)
VIOXX (2208 patients)
ZOMETA (2195 patients)
ASPIRIN (1348 patients)
AREDIA (1299 patients)
NEXIUM (759 patients)
ALENDRONATE SODIUM (756 patients)
PRILOSEC (688 patients)
CELEBREX (674 patients)
PREDNISONE (674 patients)
FOSAMAX PLUS D (669 patients)
NEURONTIN (669 patients)
LASIX (659 patients)
AMBIEN (644 patients)
COUMADIN (636 patients)
LIPITOR (634 patients)
SYNTHROID (598 patients)
ACCUTANE (580 patients)
PROTONIX (558 patients)
LISINOPRIL (541 patients)
OXYCONTIN (535 patients)
VICODIN (521 patients)
PERCOCET (511 patients)
LEVAQUIN (487 patients)
DEXAMETHASONE (480 patients)
CALCIUM (UNSPECIFIED) (470 patients)
LORTAB (456 patients)
PREVACID (441 patients)
XANAX (438 patients)
ZOCOR (431 patients)
ATIVAN (419 patients)
FOLIC ACID (418 patients)
PREMARIN (400 patients)
AMOXICILLIN (395 patients)
ZOLOFT (385 patients)
IBUPROFEN (384 patients)
AVONEX (383 patients)
THALIDOMIDE (382 patients)
DURAGESIC-100 (382 patients)
HYDROCHLOROTHIAZIDE (381 patients)
LORAZEPAM (379 patients)
OXYCODONE HCL (374 patients)
LEXAPRO (373 patients)
DECADRON (369 patients)
ALBUTEROL (355 patients)
SEROQUEL (355 patients)
VITAMINS (UNSPECIFIED) (353 patients)
POTASSIUM CHLORIDE (351 patients)
ZOFRAN (336 patients)
GABAPENTIN (330 patients)
MORPHINE (325 patients)
TOPROL-XL (325 patients)
PLAVIX (323 patients)
REGLAN (316 patients)
DILAUDID (313 patients)
LYRICA (310 patients)
BONIVA (310 patients)
FLEXERIL (304 patients)
ATENOLOL (300 patients)
FUROSEMIDE (298 patients)
METHOTREXATE (297 patients)
MULTI-VITAMINS (293 patients)
NORVASC (293 patients)
CYMBALTA (285 patients)
CHEMOTHERAPEUTICS NOS (283 patients)
TAMOXIFEN CITRATE (281 patients)
PROZAC (275 patients)
FEMARA (272 patients)
CLINDAMYCIN (272 patients)
ALLEGRA (272 patients)
COLACE (268 patients)
CELEXA (268 patients)
PAXIL (266 patients)
SIMVASTATIN (263 patients)
ZANTAC (262 patients)
CALCIUM (260 patients)
VITAMIN D (UNSPECIFIED) (260 patients)
VITAMIN E (259 patients)
ACETAMINOPHEN (258 patients)
ARIMIDEX (258 patients)
ARANESP (257 patients)
OMEPRAZOLE (252 patients)
ADVAIR DISKUS 100/50 (251 patients)
PERIDEX (251 patients)
COMPAZINE (250 patients)
ZITHROMAX (247 patients)
WARFARIN SODIUM (245 patients)
MORPHINE SULFATE (245 patients)
EFFEXOR (241 patients)
FENTANYL (239 patients)
AROMASIN (236 patients)
RADIATION THERAPY (236 patients)
FORTEO (235 patients)
VITAMIN D (235 patients)
ENBREL (229 patients)
[THERAPY UNSPECIFIED] (228 patients)
REVLIMID (226 patients)
CIPROFLOXACIN (225 patients)
WELLBUTRIN (224 patients)
PREDNISONE TAB (221 patients)
TAXOTERE (221 patients)
VELCADE (221 patients)
PEPCID (220 patients)
ASCORBIC ACID (219 patients)
CEPHALEXIN (217 patients)
LOVENOX (214 patients)
CALCIUM CARBONATE (212 patients)
VALIUM (212 patients)
MS CONTIN (212 patients)
FASLODEX (211 patients)
MOTRIN (209 patients)
CHLORHEXIDINE GLUCONATE (208 patients)
HUMIRA (202 patients)
ALPRAZOLAM (202 patients)
DIOVAN (201 patients)
ZYRTEC (199 patients)
XELODA (197 patients)
FLONASE (195 patients)
HYDROCODONE (195 patients)
HYDROCODONE BITARTRATE (193 patients)
CLONAZEPAM (192 patients)
ACTONEL (191 patients)
PROCRIT /00909301/ (189 patients)
KLOR-CON (186 patients)
ELAVIL (186 patients)
KEFLEX (185 patients)
CLARITIN (183 patients)
LOPRESSOR (182 patients)
CRESTOR (182 patients)
DARVOCET-N 100 (181 patients)
DARVOCET-N 50 (179 patients)
ULTRAM (177 patients)
NITROGLYCERIN (176 patients)
FLOMAX (175 patients)
ADRIAMYCIN PFS (175 patients)
DOXYCYCLINE (171 patients)
METOPROLOL TARTRATE (171 patients)
KLONOPIN (170 patients)
LEVOTHYROXINE SODIUM (170 patients)
SPIRIVA (168 patients)
LUPRON (167 patients)
METFORMIN HCL (166 patients)
TYSABRI (166 patients)
RESTORIL (164 patients)
AVELOX (163 patients)
LANTUS (163 patients)
SOMA (162 patients)
AUGMENTIN '125' (161 patients)
ALLOPURINOL (161 patients)
AMITRIPTYLINE HCL (161 patients)
HERCEPTIN (160 patients)
IRON (158 patients)
PREMPRO (158 patients)
ACYCLOVIR (157 patients)
GLUCOPHAGE (156 patients)
NORCO (156 patients)
DIAZEPAM (155 patients)
TYLENOL (154 patients)
DIFLUCAN (151 patients)
VANCOMYCIN (150 patients)
DIGOXIN (149 patients)
OXYCODONE (149 patients)
FLUCONAZOLE (149 patients)
METRONIDAZOLE (148 patients)
SINGULAIR (147 patients)
CYTOXAN (146 patients)
NYSTATIN (144 patients)
PROMETHAZINE (143 patients)
PRAVACHOL (141 patients)
ACTOS (141 patients)
TRAZODONE HCL (141 patients)
DEMEROL (140 patients)
TEMAZEPAM (140 patients)
TRAZODONE HYDROCHLORIDE (139 patients)
PROCRIT (137 patients)
CYCLOBENZAPRINE (137 patients)
GEMZAR (136 patients)
FISH OIL (135 patients)
COREG (134 patients)
VITAMIN B-12 (134 patients)
BEXTRA (132 patients)
METHADONE HCL (132 patients)
LIDOCAINE (132 patients)
ZANAFLEX (131 patients)
BENADRYL (130 patients)
ACIPHEX (129 patients)
TYLENOL-500 (128 patients)
FERROUS SULFATE TAB (128 patients)
INSULIN (127 patients)
HEPARIN (126 patients)
TRAMADOL HCL (126 patients)
PHENERGAN (125 patients)
MEGACE (125 patients)
TYLENOL (CAPLET) (124 patients)
OXYCODONE HCL AND ACETAMINOPHEN (123 patients)
NAPROXEN (122 patients)
MELPHALAN HYDROCHLORIDE (122 patients)
CALCIUM (UNSPECIFIED) AND VITAMIN D (UNSPECIFIED) (121 patients)
SKELAXIN (121 patients)
ZETIA (120 patients)
MOBIC (120 patients)
MULTI-VITAMIN (119 patients)
VASOTEC (119 patients)
LIDODERM (119 patients)
TAXOL (119 patients)
CARDIZEM (118 patients)
ALTACE (117 patients)
FLAGYL (116 patients)
AZITHROMYCIN (116 patients)
BACLOFEN (115 patients)

Most common side effects for patients taking CYCLOSPORINE:

PYREXIA (2084 patients)
CYTOMEGALOVIRUS INFECTION (1799 patients)
BLOOD CREATININE INCREASED (1236 patients)
GRAFT VERSUS HOST DISEASE (1209 patients)
DIARRHOEA (1199 patients)
SEPSIS (1192 patients)
PNEUMONIA (905 patients)
RENAL FAILURE ACUTE (869 patients)
ANAEMIA (850 patients)
RENAL IMPAIRMENT (848 patients)
NAUSEA (811 patients)
RENAL FAILURE (792 patients)
ACUTE GRAFT VERSUS HOST DISEASE (753 patients)
DYSPNOEA (741 patients)
DRUG INTERACTION (740 patients)
HYPERTENSION (737 patients)
DRUG INEFFECTIVE (733 patients)
VOMITING (730 patients)
MULTI-ORGAN FAILURE (723 patients)
RESPIRATORY FAILURE (682 patients)
PANCYTOPENIA (624 patients)
KIDNEY TRANSPLANT REJECTION (622 patients)
ABDOMINAL PAIN (600 patients)
THROMBOCYTOPENIA (586 patients)
CHRONIC GRAFT VERSUS HOST DISEASE (574 patients)
INFECTION (571 patients)
FEBRILE NEUTROPENIA (570 patients)
LYMPHOCELE (568 patients)
URINARY TRACT INFECTION (560 patients)
ACUTE GRAFT VERSUS HOST DISEASE IN SKIN (556 patients)
LEUKOPENIA (519 patients)
HEADACHE (515 patients)
CONVULSION (513 patients)
HAEMOGLOBIN DECREASED (507 patients)
ASTHENIA (501 patients)
PROTEINURIA (449 patients)
OEDEMA PERIPHERAL (447 patients)
PLATELET COUNT DECREASED (443 patients)
EPSTEIN-BARR VIRUS INFECTION (441 patients)
HAEMODIALYSIS (433 patients)
DEATH (431 patients)
RHABDOMYOLYSIS (430 patients)
RASH (425 patients)
COMPLICATIONS OF TRANSPLANTED KIDNEY (424 patients)
THROMBOTIC MICROANGIOPATHY (423 patients)
HYPOTENSION (419 patients)
BLOOD BILIRUBIN INCREASED (418 patients)
TRANSPLANT REJECTION (418 patients)
ALANINE AMINOTRANSFERASE INCREASED (413 patients)
NEPHROPATHY TOXIC (413 patients)
DEHYDRATION (411 patients)
MUCOSAL INFLAMMATION (404 patients)
HAEMATOMA (398 patients)
PLEURAL EFFUSION (398 patients)
FATIGUE (395 patients)
COUGH (381 patients)
HERPES ZOSTER (372 patients)
DISEASE RECURRENCE (367 patients)
INTERSTITIAL LUNG DISEASE (364 patients)
PAIN (364 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (363 patients)
WEIGHT DECREASED (361 patients)
SEPTIC SHOCK (361 patients)
MALAISE (361 patients)
OEDEMA (347 patients)
ASPERGILLOSIS (344 patients)
CONDITION AGGRAVATED (344 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (341 patients)
NEUTROPENIA (339 patients)
LIVER FUNCTION TEST ABNORMAL (334 patients)
ARTHRALGIA (331 patients)
HEPATIC FUNCTION ABNORMAL (327 patients)
WHITE BLOOD CELL COUNT DECREASED (326 patients)
ACUTE GRAFT VERSUS HOST DISEASE IN INTESTINE (325 patients)
CARDIAC FAILURE (323 patients)
STAPHYLOCOCCAL INFECTION (311 patients)
CYSTITIS HAEMORRHAGIC (309 patients)
MYALGIA (308 patients)
EPSTEIN-BARR VIRUS ASSOCIATED LYMPHOPROLIFERATIVE DISORDER (308 patients)
CHOLELITHIASIS (306 patients)
DIABETES MELLITUS (301 patients)
HISTIOCYTOSIS HAEMATOPHAGIC (294 patients)
C-REACTIVE PROTEIN INCREASED (292 patients)
BONE MARROW FAILURE (290 patients)
ERYTHEMA (282 patients)
VENOOCCLUSIVE LIVER DISEASE (275 patients)
HAEMATURIA (274 patients)
DRUG EXPOSURE DURING PREGNANCY (273 patients)
CALCULUS URETERIC (272 patients)
CELLULITIS (270 patients)
LIVER DISORDER (261 patients)
TREMOR (260 patients)
STOMATITIS (257 patients)
WEIGHT INCREASED (256 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (255 patients)
HEPATIC FAILURE (253 patients)
CONFUSIONAL STATE (251 patients)
LYMPHADENOPATHY (251 patients)
PAIN IN EXTREMITY (247 patients)
DISEASE PROGRESSION (247 patients)
BLOOD TRIGLYCERIDES INCREASED (246 patients)
CHEST PAIN (246 patients)
BACK PAIN (243 patients)
BLOOD UREA INCREASED (242 patients)
CHOLESTASIS (238 patients)
DRUG LEVEL INCREASED (233 patients)
GASTROINTESTINAL HAEMORRHAGE (232 patients)
IMMUNOSUPPRESSANT DRUG LEVEL INCREASED (232 patients)
HYPOXIA (231 patients)
ASCITES (231 patients)
NEPHROTIC SYNDROME (230 patients)
MUSCULAR WEAKNESS (230 patients)
LUNG INFILTRATION (230 patients)
HYPERBILIRUBINAEMIA (229 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (228 patients)
ACUTE RESPIRATORY DISTRESS SYNDROME (226 patients)
BRONCHOPULMONARY ASPERGILLOSIS (225 patients)
HYPERKALAEMIA (220 patients)
PSORIASIS (218 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (216 patients)
NEUROTOXICITY (212 patients)
PNEUMOCYSTIS JIROVECI PNEUMONIA (211 patients)
OLIGURIA (209 patients)
LYMPHOPROLIFERATIVE DISORDER (209 patients)
BK VIRUS INFECTION (209 patients)
BLOOD CHOLESTEROL INCREASED (208 patients)
RENAL FAILURE CHRONIC (203 patients)
CEREBRAL HAEMORRHAGE (201 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (200 patients)
CHILLS (200 patients)
BLOOD PRESSURE INCREASED (200 patients)
ENCEPHALOPATHY (199 patients)
BASAL CELL CARCINOMA (194 patients)
HEPATOTOXICITY (194 patients)
STEM CELL TRANSPLANT (193 patients)
FALL (193 patients)
MYOCARDIAL INFARCTION (193 patients)
GAIT DISTURBANCE (193 patients)
TACHYCARDIA (192 patients)
SOMNOLENCE (192 patients)
DIZZINESS (191 patients)
THERAPEUTIC RESPONSE DECREASED (191 patients)
DRUG TOXICITY (191 patients)
FUNGAL INFECTION (190 patients)
ADENOVIRUS INFECTION (189 patients)
PRURITUS (186 patients)
ANXIETY (184 patients)
RENAL TUBULAR NECROSIS (184 patients)
CHRONIC ALLOGRAFT NEPHROPATHY (184 patients)
POST PROCEDURAL COMPLICATION (183 patients)
HYPERGLYCAEMIA (182 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (182 patients)
BACTERIAL INFECTION (181 patients)
PULMONARY OEDEMA (181 patients)
PSEUDOMONAS INFECTION (181 patients)
WHITE BLOOD CELL COUNT INCREASED (180 patients)
THERAPEUTIC AGENT TOXICITY (179 patients)
ATRIAL FIBRILLATION (176 patients)
JAUNDICE (174 patients)
CYTOMEGALOVIRUS VIRAEMIA (173 patients)
SKIN LESION (169 patients)
TRANSAMINASES INCREASED (168 patients)
VENOOCCLUSIVE DISEASE (168 patients)
GRAND MAL CONVULSION (166 patients)
DIALYSIS (166 patients)
RESPIRATORY DISTRESS (166 patients)
INFLAMMATION (165 patients)
DECREASED APPETITE (165 patients)
ANOREXIA (164 patients)
RENAL DISORDER (163 patients)
REVERSIBLE POSTERIOR LEUKOENCEPHALOPATHY SYNDROME (163 patients)
STAPHYLOCOCCAL SEPSIS (161 patients)
ACUTE MYELOID LEUKAEMIA (160 patients)
ENTEROCOCCAL INFECTION (157 patients)
TRANSPLANT FAILURE (157 patients)
HEPATIC ENZYME INCREASED (157 patients)
CARDIAC FAILURE CONGESTIVE (154 patients)
PNEUMONIA CYTOMEGALOVIRAL (154 patients)
LIVER TRANSPLANT REJECTION (151 patients)
PERICARDIAL EFFUSION (151 patients)
CANDIDIASIS (151 patients)
KAPOSI'S SARCOMA (150 patients)
ABDOMINAL PAIN UPPER (149 patients)
LOW DENSITY LIPOPROTEIN INCREASED (148 patients)
PARAESTHESIA (147 patients)
CYTOMEGALOVIRUS TEST POSITIVE (145 patients)
ANURIA (145 patients)
OSTEOPOROSIS (144 patients)
CHOLECYSTITIS (144 patients)
BACTERIAL SEPSIS (144 patients)
GRAFT DYSFUNCTION (143 patients)
GASTROENTERITIS (142 patients)
APLASTIC ANAEMIA (142 patients)
DEPRESSION (141 patients)
CARDIAC ARREST (139 patients)
BRONCHIECTASIS (138 patients)
CYTOMEGALOVIRUS ANTIGEN POSITIVE (136 patients)
DEEP VEIN THROMBOSIS (136 patients)
MOUTH ULCERATION (135 patients)
OSTEONECROSIS (135 patients)
HAEMATOCRIT DECREASED (133 patients)
LUNG DISORDER (133 patients)
HYPOAESTHESIA (133 patients)
HYPERCHOLESTEROLAEMIA (132 patients)
HYPONATRAEMIA (131 patients)
NO THERAPEUTIC RESPONSE (130 patients)
PULMONARY EMBOLISM (130 patients)
ACUTE GRAFT VERSUS HOST DISEASE IN LIVER (130 patients)
URINARY TRACT INFECTION ENTEROCOCCAL (130 patients)
ABDOMINAL DISTENSION (129 patients)

In addition to reviewing our up-to-date FDA research, users may interact with the FactMed community - currently one million members and growing! FactMed online research and discussions are read by patients, scientists, physicians, and other interested health care parties. Post follow up Questions to learn from our diverse readership. Likewise, patients who have experienced unwanted effects are encouraged to share their Concerns to help educate and inform our members.

Recent FactMed Activity for CYCLOSPORINE

Issue	Description / Topic	Timestamp
QUESTION VISUAL DISTURBANCE	I've been on cyclosporine 50mg for 4 weeks, then my dose was increased to 75mg per day. It has been prescribed for SLE/lupus. It has been extremely useful for lupus but I experienced blurry vision in my left eye and also my left eye's lid is difficult to open in the night. With my rheumatologist's agreement I've stopped the drug for a week to see if these side effects disappear. Do you have any experience of these side effects and if so, did they resolve with a decrease or ceasing the drug?	2014-11-22 16:21:56
QUESTION EXPIRED DRUG ADMINISTERED	I just realized today I was taking 100 mg 2 x a day that expired on April 2015. My prescription was filled 5-22-15. I have taken 11 of them and threw one away today when I realized they were expired.	2015-05-30 13:01:08
CONCERN SNEEZING	150 MG CYCLOSPORINE FOR RENAL TRANSPLANT. THIS MEDICINE CAUSE S ME TO COUGH AND SNEEZE.	2015-10-06 17:03:53
QUESTION DRUG INTERACTION	Is it OK with Phenytoin,SImvastatin and Thyroxine?	2015-11-18 15:39:24
QUESTION EXPIRED DRUG ADMINISTERED	I have a box of cyclosporine that has been expired last oct 2015. Its already dec now. Can I still take the meds eventhough its outdated? Will it cause me any side effects?	2015-12-16 09:19:30
QUESTION FOLLICULITIS	i have been taking 200mg of cyclosporine per day prescribed for severe eczema for about 12 months now. Over the last 4 months I have developed strange spots allover my back and the sides of my face I saw my dermatologist last week and she was unsure what it is and did 2 biopsies, and stopped the cyclosporin what's terrifying me is she did mention the possibility of lymphoma anyone else had a similar thing	2016-03-07 15:48:54
QUESTION THIRST	Anyone get extremely thirsty on this medication?	2016-09-04 14:20:44
QUESTION THIRST	Anyone get extremely thirsty on this medication?	2016-09-04 14:22:34
QUESTION EXPIRED DRUG ADMINISTERED	Im taken ciclosporine but arealised They expires since 2014 is ok to keep taken them no money to doctor	2016-10-08 23:43:30
QUESTION PREGNANCY TEST FALSE POSITIVE	I have been taking cyclosporine for two weeks now,I am a week late on my period and I'm normally like clock work.ive done pregnancy tests which are negative.could this have effect on the reading	2016-10-10 15:53:00
QUESTION BLADDER CANCER	Can cyclosporine cause urinary bladder cancer. I am taking 25 mg in the morning and 50 mg at night for my kidney transplant for several years now? I will appreciate your reply. Thanks.	2016-11-03 13:58:10
QUESTION EXPIRED DRUG ADMINISTERED	What will happen if I take expired ciclsplorin for psoriasis.	2016-11-23 17:55:56
QUESTION EXPIRED DRUG ADMINISTERED	I see my question but don't see an answer. Will taking expired cyclosporine be harmful? Does expired cyclosporine still work enough to prevent rejection?	2017-02-01 14:12:13
QUESTION NEUTROPENIA	I have been on cyclosporine for 31 years (liver transplant). For a number of years my white cell count has been just out of the normal range (every now and then it will be just in the normal range). This last blood test also showed my neutrophils to be out of the normal range. Could there be a relationship between my taking cyclosporine and these tests. I have normal blood pressure and aren't on any other immune suppressants.	2017-06-16 05:24:06

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