Is GASTROINTESTINAL NECROSIS a side effect of FOSAMAX ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of FOSAMAX patients who developed GASTROINTESTINAL NECROSIS.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 21 individuals taking FOSAMAX reported GASTROINTESTINAL NECROSIS to the FDA. A total of 78367 FOSAMAX drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between FOSAMAX and GASTROINTESTINAL NECROSIS. In doing so, we compare FOSAMAX with other drugs that cause GASTROINTESTINAL NECROSIS, to help you evaluate whether or not FOSAMAX causes GASTROINTESTINAL NECROSIS. Likewise, this page shows the most highly-reported side effects of FOSAMAX, so you can see if GASTROINTESTINAL NECROSIS ranks among FOSAMAX's most well-known side effects.

Summary Statistics
Reports of FOSAMAX causing GASTROINTESTINAL NECROSIS: 21
Reports of any side effect of FOSAMAX : 78367
Percentage of FOSAMAX patients where GASTROINTESTINAL NECROSIS is a reported side effect: 0.0268%

FDA reports of any drug causing GASTROINTESTINAL NECROSIS : 1414
Average percentage for all medicated patients where GASTROINTESTINAL NECROSIS is reported as a complication: 0.0089%

Physician opinion on FOSAMAX as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing FOSAMAX:

OSTEOPOROSIS ( 23098 patients )
OSTEOPENIA ( 7095 patients )
OSTEOPOROSIS PROPHYLAXIS ( 1661 patients )
DRUG USE FOR UNKNOWN INDICATION ( 898 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 706 patients )
PROPHYLAXIS ( 427 patients )
BONE DENSITY DECREASED ( 404 patients )
BONE DISORDER ( 356 patients )
OSTEOPOROSIS POSTMENOPAUSAL ( 197 patients )
OSTEOARTHRITIS ( 186 patients )
RHEUMATOID ARTHRITIS ( 146 patients )
OSTEITIS DEFORMANS ( 119 patients )
BONE LOSS ( 104 patients )
ARTHRITIS ( 71 patients )
RESORPTION BONE INCREASED ( 66 patients )
MENOPAUSE ( 54 patients )
HIP FRACTURE ( 52 patients )
STRESS FRACTURE ( 52 patients )
FRACTURE ( 50 patients )
MULTIPLE MYELOMA ( 47 patients )
SPINAL COMPRESSION FRACTURE ( 41 patients )
CALCIUM DEFICIENCY ( 39 patients )
OSTEOPOROTIC FRACTURE ( 38 patients )
SPINAL FRACTURE ( 37 patients )
BREAST CANCER ( 36 patients )
BONE DENSITY ABNORMAL ( 35 patients )
SENILE OSTEOPOROSIS ( 30 patients )
SCOLIOSIS ( 25 patients )
OSTEOGENESIS IMPERFECTA ( 25 patients )
POSTMENOPAUSE ( 25 patients )
ILL-DEFINED DISORDER ( 24 patients )
OSTEONECROSIS ( 19 patients )
HYPERCALCAEMIA ( 19 patients )
JAW FRACTURE ( 17 patients )
WRIST FRACTURE ( 16 patients )
FOOT FRACTURE ( 16 patients )
PREMATURE MENOPAUSE ( 15 patients )
FIBROMYALGIA ( 15 patients )
COMPRESSION FRACTURE ( 15 patients )
SYSTEMIC LUPUS ERYTHEMATOSUS ( 14 patients )
BACK PAIN ( 14 patients )
FRACTURED SACRUM ( 14 patients )
OSTEOSCLEROSIS ( 14 patients )
PAIN ( 14 patients )
LOWER LIMB FRACTURE ( 12 patients )
PROSTATE CANCER ( 11 patients )
HIP ARTHROPLASTY ( 11 patients )
METASTASES TO BONE ( 11 patients )
HYSTERECTOMY ( 10 patients )
NEOPLASM MALIGNANT ( 9 patients )
BONE DENSITOMETRY ( 9 patients )
JUVENILE ARTHRITIS ( 9 patients )
BONE DENSITY INCREASED ( 8 patients )
MUSCLE SPASMS ( 8 patients )
VITAMIN D ( 8 patients )
RENAL TRANSPLANT ( 8 patients )
JOINT INSTABILITY ( 7 patients )
HYPERTENSION ( 7 patients )
PAIN IN JAW ( 7 patients )
MINERAL SUPPLEMENTATION ( 7 patients )
ARTHRALGIA ( 7 patients )
DIABETES MELLITUS ( 7 patients )
MALAISE ( 7 patients )
HOT FLUSH ( 6 patients )
GASTROOESOPHAGEAL REFLUX DISEASE ( 6 patients )
ANKLE FRACTURE ( 6 patients )
BONE MARROW OEDEMA SYNDROME ( 6 patients )
POLYMYALGIA RHEUMATICA ( 5 patients )
THORACIC VERTEBRAL FRACTURE ( 5 patients )
SPINAL OSTEOARTHRITIS ( 5 patients )
BREAST CANCER METASTATIC ( 5 patients )
SUPPLEMENTATION THERAPY ( 5 patients )
BLOOD CALCIUM DECREASED ( 5 patients )
FEMUR FRACTURE ( 5 patients )
SPINAL CORD COMPRESSION ( 5 patients )
UNEVALUABLE EVENT ( 5 patients )
BONE PAIN ( 5 patients )
VITAMIN D DEFICIENCY ( 4 patients )
HIP SURGERY ( 4 patients )
POLYARTHRITIS ( 4 patients )
BONE DEVELOPMENT ABNORMAL ( 4 patients )
HORMONE THERAPY ( 4 patients )
BONE LESION ( 4 patients )
HYPERSENSITIVITY ( 4 patients )
SPINAL DISORDER ( 4 patients )
ARTHROPATHY ( 4 patients )
RHEUMATOID VASCULITIS ( 3 patients )
FAILURE OF IMPLANT ( 3 patients )
JAW DISORDER ( 3 patients )
SJOGREN'S SYNDROME ( 3 patients )
MULTIPLE FRACTURES ( 3 patients )
FEMORAL NECK FRACTURE ( 3 patients )
BLOOD PRESSURE ( 3 patients )
BONE NEOPLASM MALIGNANT ( 3 patients )
PROSTATE CANCER RECURRENT ( 3 patients )
LUMBAR VERTEBRAL FRACTURE ( 3 patients )
DEPRESSION ( 3 patients )
STEROID THERAPY ( 3 patients )
MENOPAUSAL SYMPTOMS ( 3 patients )
PATHOLOGICAL FRACTURE ( 3 patients )
INTENTIONAL OVERDOSE ( 3 patients )
ROUTINE HEALTH MAINTENANCE ( 3 patients )
OSTEOMALACIA ( 3 patients )
FALL ( 3 patients )
SPINAL COLUMN STENOSIS ( 3 patients )
BONE CANCER METASTATIC ( 3 patients )
NUTRITIONAL SUPPORT ( 3 patients )
VITAMIN SUPPLEMENTATION ( 3 patients )
BACK DISORDER ( 3 patients )
CALCINOSIS ( 3 patients )
CARCINOEMBRYONIC ANTIGEN INCREASED ( 2 patients )
INTERVERTEBRAL DISC DEGENERATION ( 2 patients )
BENIGN PROSTATIC HYPERPLASIA ( 2 patients )
BLOOD CALCIUM ( 2 patients )
BLOOD CHOLESTEROL ABNORMAL ( 2 patients )
HYPERPARATHYROIDISM ( 2 patients )
MULTIPLE SCLEROSIS ( 2 patients )
SPINAL DEFORMITY ( 2 patients )
ANTACID THERAPY ( 2 patients )
BLOOD PRESSURE INCREASED ( 2 patients )
HYPOCALCAEMIA ( 2 patients )
TEMPORAL ARTERITIS ( 2 patients )
BIPOLAR DISORDER ( 2 patients )
COLITIS ( 2 patients )
BLOOD PRESSURE ABNORMAL ( 2 patients )
MYALGIA ( 2 patients )
PROSTATE CANCER METASTATIC ( 2 patients )
LUMBAR RADICULOPATHY ( 2 patients )
VITAMIN D DECREASED ( 2 patients )
LUNG TRANSPLANT ( 2 patients )
IMMUNISATION ( 2 patients )
INSOMNIA ( 1 patients )
BASEDOW'S DISEASE ( 1 patients )
PLASMACYTOSIS ( 1 patients )
EMPTY SELLA SYNDROME ( 1 patients )
OSTEOLYSIS ( 1 patients )
CEREBROVASCULAR ACCIDENT PROPHYLAXIS ( 1 patients )
HORMONE REPLACEMENT THERAPY ( 1 patients )
MICTURITION DISORDER ( 1 patients )
COELIAC DISEASE ( 1 patients )
TIBIA FRACTURE ( 1 patients )
ADRENOCORTICAL STEROID THERAPY ( 1 patients )
BONE FORMATION INCREASED ( 1 patients )
OSTEOPETROSIS ( 1 patients )
COLITIS ULCERATIVE ( 1 patients )
TOOTHACHE ( 1 patients )
ANGINA PECTORIS ( 1 patients )
KYPHOSIS ( 1 patients )
URTICARIA CHRONIC ( 1 patients )
CROHN'S DISEASE ( 1 patients )
BONE SCAN ABNORMAL ( 1 patients )
OTOSCLEROSIS ( 1 patients )
BONE ATROPHY ( 1 patients )
NEUROPATHIC ARTHROPATHY ( 1 patients )
ASTHMA ( 1 patients )
GUILLAIN-BARRE SYNDROME ( 1 patients )
MAJOR DEPRESSION ( 1 patients )
DOPAMINE DYSREGULATION SYNDROME ( 1 patients )
IMPACTED FRACTURE ( 1 patients )
DYSPEPSIA ( 1 patients )
BEHCET'S SYNDROME ( 1 patients )
CARPAL TUNNEL SYNDROME ( 1 patients )
EXOSTOSIS ( 1 patients )
INTRAOSSEOUS ANGIOMA ( 1 patients )
CERVICOBRACHIAL SYNDROME ( 1 patients )
THROMBOSIS PROPHYLAXIS ( 1 patients )
ABDOMINAL PAIN UPPER ( 1 patients )
BONE ELECTROSTIMULATION THERAPY ( 1 patients )
TOOTH LOSS ( 1 patients )
ADVERSE DRUG REACTION ( 1 patients )
BLOOD CHOLESTEROL INCREASED ( 1 patients )
COMPLEX REGIONAL PAIN SYNDROME ( 1 patients )
MUSCLE DISORDER ( 1 patients )
PROPHYLAXIS AGAINST GASTROINTESTINAL ULCER ( 1 patients )
LOCALISED OSTEOARTHRITIS ( 1 patients )
CONNECTIVE TISSUE DISORDER ( 1 patients )
HYPERTHYROIDISM ( 1 patients )
VERTEBRAL INJURY ( 1 patients )
SPINAL FUSION SURGERY ( 1 patients )
BODY HEIGHT DECREASED ( 1 patients )
DENTAL OPERATION ( 1 patients )
NEPHROPATHY ( 1 patients )
RADIOTHERAPY ( 1 patients )
GROIN PAIN ( 1 patients )
SPONDYLOARTHROPATHY ( 1 patients )
HAEMANGIOMA ( 1 patients )
PANNICULITIS ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with GASTROINTESTINAL NECROSIS:

ASPIRIN (115 patients)
PREDNISOLONE (95 patients)
FLUOROURACIL (86 patients)
HUMIRA (84 patients)
HEPARIN SODIUM INJECTION (73 patients)
METHOTREXATE (71 patients)
CYTARABINE (65 patients)
LASIX (62 patients)
AVASTIN (59 patients)
PREDNISONE (57 patients)
FOLIC ACID (56 patients)
CYCLOPHOSPHAMIDE (56 patients)
CISPLATIN (54 patients)
OMEPRAZOLE (53 patients)
DEXAMETHASONE (47 patients)
REMICADE (46 patients)
ETOPOSIDE (46 patients)
ACETAMINOPHEN (45 patients)
BEVACIZUMAB (43 patients)
TAXOTERE (39 patients)
NORVASC (39 patients)
ALLOPURINOL (36 patients)
PROGRAF (35 patients)
CARBOPLATIN (34 patients)
FORTEO (34 patients)
ACCUTANE (33 patients)
NOVOSEVEN (33 patients)
TAXOL (33 patients)
MYCOPHENOLATE MOFETIL (32 patients)
IBUPROFEN (31 patients)
WARFARIN SODIUM (31 patients)
LEUCOVORIN CALCIUM (29 patients)
VITAMIN B-12 (29 patients)
ALBUTEROL (28 patients)
LANSOPRAZOLE (27 patients)
VINCRISTINE SULFATE (27 patients)
RENAGEL (26 patients)
CLOZAPINE (26 patients)
OXYCODONE HCL (26 patients)
LIPITOR (25 patients)
METHYLPREDNISOLONE (25 patients)
ALIMTA (24 patients)
KETEK (24 patients)
MORPHINE (24 patients)
NEXIUM (24 patients)
FUROSEMIDE (24 patients)
CYCLOSPORINE (24 patients)
LEVOTHYROXINE SODIUM (23 patients)
DIANEAL (23 patients)
LORAZEPAM (23 patients)
TRIAMCINOLONE (22 patients)
EMEND (22 patients)
SOLU-MEDROL (22 patients)
TACROLIMUS (22 patients)
PRESSORS (22 patients)
PAXIL (22 patients)
CLOZARIL (22 patients)
LOPERAMIDE (22 patients)
PRILOSEC (22 patients)
LISINOPRIL (22 patients)
IRINOTECAN HCL (21 patients)
DAPSONE (21 patients)
ERYTHROMYCIN (21 patients)
FOSAMAX (21 patients)
REVLIMID (21 patients)
AVONEX (21 patients)
ENBREL (20 patients)
POTASSIUM CHLORIDE (20 patients)
SULFUR (20 patients)
FAMOTIDINE (19 patients)
ACHROMYCIN (19 patients)
DOCETAXEL (19 patients)
ZOCOR (19 patients)
MINOCIN (19 patients)
OXALIPLATIN (19 patients)
SUMYCIN (19 patients)
ONDANSETRON (19 patients)
TOPICYCLINE (19 patients)
CIPROFLOXACIN (19 patients)
BENZAGEL (19 patients)
CALCIUM WITH VITAMIN D (19 patients)
1 CONCOMITANT DRUG (18 patients)
ADRIAMYCIN PFS (18 patients)
PREDNISONE TAB (18 patients)
HYDROCHLOROTHIAZIDE (18 patients)
BISOPROLOL FUMARATE (18 patients)
OXYCONTIN (18 patients)
DOXORUBICIN HCL (17 patients)
TOPROL-XL (17 patients)
DIAZEPAM (17 patients)
SYNTHROID (17 patients)
XANAX (17 patients)
DEXAMETHASONE TAB (17 patients)
ISONIAZID (17 patients)
PACLITAXEL (17 patients)
ZOFRAN (16 patients)
LEVAQUIN (16 patients)
VANCOMYCIN (16 patients)
DECADRON (16 patients)
NASONEX (16 patients)
FENTANYL (16 patients)
CLONAZEPAM (16 patients)
NEURONTIN (15 patients)
DAUNORUBICIN HCL (15 patients)
PARAPLATIN (15 patients)
FLUCONAZOLE (15 patients)
ADALAT CC (15 patients)
MULTI-VITAMINS (15 patients)
METOCLOPRAMIDE (15 patients)
RHEUMATREX (15 patients)
COUMADIN (15 patients)
TERCIAN (15 patients)
KAYEXALATE (15 patients)
CELEBREX (14 patients)
LOPID (14 patients)
ELPLAT (14 patients)
ZYPREXA (14 patients)
VELCADE (14 patients)
CELEXA (14 patients)
WELLBUTRIN (14 patients)
BYETTA (14 patients)
VINCRISTINE (14 patients)
ACCOLATE (13 patients)
CEFZIL (13 patients)
ADVAIR DISKUS 100/50 (13 patients)
XELODA (13 patients)
METOPROLOL TARTRATE (13 patients)
NEXAVAR (13 patients)
CAPECITABINE (13 patients)
CALCIUM CARBONATE (13 patients)
HYDROCODONE/GUAIFENESIN COUGH SYRUP (12 patients)
CLARINEX (12 patients)
ACYCLOVIR (12 patients)
SIMVASTATIN (12 patients)
LOTENSIN /00909102/ (12 patients)
ENALAPRIL MALEATE (12 patients)
MAGNESIUM OXIDE (12 patients)
INSULIN (12 patients)
DICLOFENAC SODIUM (12 patients)
DIPHENHYDRAMINE HCL (12 patients)
CLEOCIN (12 patients)
RISPERDAL (12 patients)
ATENOLOL (12 patients)
CYTOXAN (12 patients)
AZATHIOPRINE (12 patients)
TENORMIN (11 patients)
METOPROLOL SUCCINATE (11 patients)
TAKEPRON (11 patients)
VITAMIN E (11 patients)
IDARUBICIN HCL (11 patients)
DOPAMINE HCL (11 patients)
URBASON (11 patients)
LOVENOX (11 patients)
VORICONAZOLE (11 patients)
PLAVIX (11 patients)
DIGOXIN (11 patients)
TOCILIZUMAB (11 patients)
RAMIPRIL (11 patients)
KYTRIL (11 patients)
BEXTRA (11 patients)
NITROGLYCERIN (11 patients)
ASCORBIC ACID (11 patients)
ATIVAN (11 patients)
ATORVASTATIN CALCIUM (11 patients)
QUETIAPINE FUMARATE (10 patients)
FRESH FROZEN PLASMA (10 patients)
LACTULOSE (10 patients)
VITAMIN D (10 patients)
EPINEPHRINE (10 patients)
PREVISCAN (10 patients)
NEULASTA (10 patients)
ACTONEL (10 patients)
K-DUR (10 patients)
RITUXIMAB (10 patients)
PREMARIN (10 patients)
MORPHINE SULFATE (10 patients)
TRAMADOL HCL (10 patients)
ANTIHYPERTENSIVES (10 patients)
TYLENOL EXTRA-STRENGTH (10 patients)
TS-1 (10 patients)
SIMULECT (10 patients)
PRADAXA (10 patients)
HEPARIN (10 patients)
LOXONIN (10 patients)
LYRICA (10 patients)
PANTOPRAZOLE SODIUM (10 patients)
PREVACID (10 patients)
THYMOGLOBULIN (9 patients)
ELOXATIN (9 patients)
BLOPRESS (9 patients)
HEPARIN SODIUM (9 patients)
M.V.I. (9 patients)
DIOVAN (9 patients)
RANITIDINE (9 patients)
ALDACTONE (9 patients)
FLUDARABINE PHOSPHATE (9 patients)
NIFEDIPINE (9 patients)
LOPRESSOR (9 patients)
SUTENT (9 patients)
ERBITUX (9 patients)
ETANERCEPT (9 patients)
PROTYLOL (9 patients)
PROTONIX (9 patients)
NEUPOGEN (9 patients)
CALCIUM (9 patients)
SEROQUEL (9 patients)
CALCIUM LEVOFOLINATE (9 patients)
HALDOL (9 patients)
EPIRUBICIN (9 patients)
CC-5013 (LENALIDOMIDE) (CAPSULES) (9 patients)

Most common side effects for patients taking FOSAMAX:

FEMUR FRACTURE (26988 patients)
FALL (21241 patients)
OSTEONECROSIS (15354 patients)
OSTEOARTHRITIS (14625 patients)
ANXIETY (14421 patients)
DEPRESSION (14302 patients)
HYPERTENSION (12928 patients)
LOW TURNOVER OSTEOPATHY (12755 patients)
ARTHRALGIA (11612 patients)
TOOTH DISORDER (11082 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (10896 patients)
BACK PAIN (10530 patients)
OSTEOMYELITIS (10062 patients)
PAIN IN EXTREMITY (9975 patients)
IMPAIRED HEALING (9640 patients)
OSTEONECROSIS OF JAW (8591 patients)
HYPERLIPIDAEMIA (8300 patients)
DENTAL CARIES (8209 patients)
ARTHROPATHY (8098 patients)
FATIGUE (7993 patients)
PAIN (7692 patients)
ANAEMIA (7678 patients)
OSTEOPOROSIS (7561 patients)
NAUSEA (7433 patients)
URINARY TRACT INFECTION (7395 patients)
CHEST PAIN (6884 patients)
BLOOD CHOLESTEROL INCREASED (6753 patients)
CATARACT (6673 patients)
DIARRHOEA (6626 patients)
STRESS FRACTURE (6499 patients)
INSOMNIA (6493 patients)
ADVERSE DRUG REACTION (6377 patients)
SPINAL OSTEOARTHRITIS (6335 patients)
HEADACHE (6320 patients)
BONE DISORDER (6190 patients)
FOOT FRACTURE (6048 patients)
INTERVERTEBRAL DISC DEGENERATION (6026 patients)
DIZZINESS (5996 patients)
ARTHRITIS (5982 patients)
OEDEMA PERIPHERAL (5869 patients)
BURSITIS (5732 patients)
CONSTIPATION (5673 patients)
BRONCHITIS (5575 patients)
CONTUSION (5358 patients)
ORAL INFECTION (5327 patients)
DYSPNOEA (5093 patients)
JAW DISORDER (5076 patients)
DRUG HYPERSENSITIVITY (5071 patients)
ADVERSE EVENT (5052 patients)
HAEMORRHOIDS (5048 patients)
PNEUMONIA (5009 patients)
SINUSITIS (4850 patients)
VITAMIN D DEFICIENCY (4827 patients)
TOOTH FRACTURE (4825 patients)
OSTEOPENIA (4783 patients)
EXOSTOSIS (4752 patients)
WEIGHT DECREASED (4717 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (4589 patients)
HYPERCHOLESTEROLAEMIA (4571 patients)
COUGH (4558 patients)
BONE DENSITY DECREASED (4339 patients)
CELLULITIS (4339 patients)
MUSCLE SPASMS (4274 patients)
DIVERTICULUM (4269 patients)
INTERVERTEBRAL DISC PROTRUSION (4263 patients)
ASTHMA (4225 patients)
INFECTION (4122 patients)
RIB FRACTURE (4074 patients)
ROTATOR CUFF SYNDROME (4073 patients)
GAIT DISTURBANCE (4049 patients)
DRUG INEFFECTIVE (4022 patients)
ASTHENIA (4007 patients)
HYPOTHYROIDISM (3889 patients)
VOMITING (3850 patients)
FRACTURE NONUNION (3804 patients)
WEIGHT INCREASED (3765 patients)
CARPAL TUNNEL SYNDROME (3725 patients)
HIATUS HERNIA (3717 patients)
MYALGIA (3629 patients)
TOOTH ABSCESS (3597 patients)
UPPER RESPIRATORY TRACT INFECTION (3543 patients)
DYSPEPSIA (3527 patients)
ABSCESS (3503 patients)
GINGIVAL DISORDER (3439 patients)
RASH (3376 patients)
ROAD TRAFFIC ACCIDENT (3374 patients)
TEMPOROMANDIBULAR JOINT SYNDROME (3349 patients)
ORAL DISORDER (3338 patients)
PAIN IN JAW (3320 patients)
ABDOMINAL PAIN (3311 patients)
HIP FRACTURE (3264 patients)
HYPOAESTHESIA (3263 patients)
DEVICE FAILURE (3209 patients)
HERPES ZOSTER (3198 patients)
DYSPHAGIA (3194 patients)
CORONARY ARTERY DISEASE (3194 patients)
PYREXIA (3183 patients)
ANAEMIA POSTOPERATIVE (3140 patients)
GASTRITIS (3133 patients)
COLONIC POLYP (3119 patients)
MUSCULOSKELETAL PAIN (3084 patients)
PARAESTHESIA (3034 patients)
NEUROPATHY PERIPHERAL (2933 patients)
PALPITATIONS (2929 patients)
OVERDOSE (2912 patients)
SCOLIOSIS (2910 patients)
TENDONITIS (2903 patients)
NECK PAIN (2895 patients)
SCIATICA (2821 patients)
ORAL TORUS (2783 patients)
DEHYDRATION (2721 patients)
GASTROINTESTINAL DISORDER (2689 patients)
SPINAL COLUMN STENOSIS (2673 patients)
SYNCOPE (2648 patients)
TOOTH LOSS (2638 patients)
SPONDYLOLISTHESIS (2634 patients)
HYPOKALAEMIA (2634 patients)
MUSCLE STRAIN (2627 patients)
ATRIAL FIBRILLATION (2601 patients)
MUSCULAR WEAKNESS (2590 patients)
RHINITIS ALLERGIC (2586 patients)
MALAISE (2559 patients)
GINGIVAL BLEEDING (2556 patients)
SINUS DISORDER (2556 patients)
RHEUMATOID ARTHRITIS (2552 patients)
HYPERSENSITIVITY (2522 patients)
CARDIAC DISORDER (2489 patients)
HYPOTENSION (2470 patients)
CARDIAC FAILURE CONGESTIVE (2442 patients)
DEEP VEIN THROMBOSIS (2419 patients)
PERIODONTAL DISEASE (2381 patients)
ANKLE FRACTURE (2355 patients)
TOOTH INFECTION (2341 patients)
GALLBLADDER DISORDER (2331 patients)
CARDIAC MURMUR (2323 patients)
SPINAL DISORDER (2312 patients)
CEREBROVASCULAR ACCIDENT (2310 patients)
MENISCUS LESION (2296 patients)
ABDOMINAL DISCOMFORT (2277 patients)
IRRITABLE BOWEL SYNDROME (2262 patients)
CHOLELITHIASIS (2249 patients)
WRIST FRACTURE (2249 patients)
FRACTURE (2240 patients)
SPINAL COMPRESSION FRACTURE (2237 patients)
FOOT DEFORMITY (2234 patients)
VERTIGO (2198 patients)
TOOTHACHE (2195 patients)
URINARY INCONTINENCE (2180 patients)
STOMATITIS (2156 patients)
NEPHROLITHIASIS (2154 patients)
LUMBAR SPINAL STENOSIS (2135 patients)
UTERINE DISORDER (2121 patients)
LUNG NEOPLASM (2101 patients)
TRANSIENT ISCHAEMIC ATTACK (2098 patients)
PERIODONTITIS (2061 patients)
MIGRAINE (2056 patients)
BLOOD PRESSURE INCREASED (2054 patients)
FRACTURE DELAYED UNION (2045 patients)
DIABETES MELLITUS (2040 patients)
MYOCARDIAL INFARCTION (2033 patients)
INJURY (2010 patients)
ABDOMINAL PAIN UPPER (2001 patients)
MITRAL VALVE INCOMPETENCE (1998 patients)
RESORPTION BONE INCREASED (1964 patients)
BACK DISORDER (1947 patients)
HAEMORRHAGIC ANAEMIA (1932 patients)
DRY MOUTH (1919 patients)
SYNOVIAL CYST (1915 patients)
BREAST CANCER (1892 patients)
GINGIVITIS (1887 patients)
LACERATION (1887 patients)
EAR PAIN (1867 patients)
RENAL FAILURE (1859 patients)
MUSCULOSKELETAL CHEST PAIN (1854 patients)
FIBROMYALGIA (1848 patients)
DECREASED APPETITE (1848 patients)
SLEEP APNOEA SYNDROME (1846 patients)
RADICULOPATHY (1827 patients)
HOT FLUSH (1822 patients)
SKIN LESION (1820 patients)
TINNITUS (1815 patients)
BALANCE DISORDER (1813 patients)
SWELLING (1811 patients)
BASAL CELL CARCINOMA (1810 patients)
JAW FRACTURE (1809 patients)
STRESS (1807 patients)
SLEEP DISORDER (1790 patients)
HAEMATURIA (1788 patients)
BONE PAIN (1787 patients)
LUMBAR RADICULOPATHY (1785 patients)
POLLAKIURIA (1767 patients)
VISION BLURRED (1751 patients)
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION (1733 patients)
JOINT EFFUSION (1724 patients)
RENAL CYST (1724 patients)
DYSLIPIDAEMIA (1721 patients)
LIGAMENT SPRAIN (1704 patients)
CYST (1697 patients)
DEATH (1691 patients)
BREAST DISORDER (1688 patients)
DRUG INTOLERANCE (1687 patients)
PRURITUS (1670 patients)
JOINT INJURY (1664 patients)
BONE LOSS (1657 patients)
FISTULA (1642 patients)
OEDEMA (1632 patients)
IRON DEFICIENCY ANAEMIA (1631 patients)
TYPE 2 DIABETES MELLITUS (1626 patients)
RENAL FAILURE CHRONIC (1625 patients)
RENAL FAILURE ACUTE (1624 patients)

In addition to reviewing our up-to-date FDA research, users may interact with the FactMed community - currently one million members and growing! FactMed online research and discussions are read by patients, scientists, physicians, and other interested health care parties. Post follow up Questions to learn from our diverse readership. Likewise, patients who have experienced unwanted effects are encouraged to share their Concerns to help educate and inform our members.

Recent FactMed Activity for FOSAMAX

Issue	Description / Topic	Timestamp
QUESTION AGE-RELATED MACULAR DEGENERATION	Should a person with markers for AMD and osteoporosis take fosamax?	2014-11-15 10:33:11
QUESTION SARCOIDOSIS	I was diagnosed with pulmonary and dermatological sarcoidosis in 2000. In 2010, I was diagnosed with Cancer (breast) and, since 2011 am taking anastrozole. My bone density now shows osteopenia and, the doctor is placing me on fosamax. When I ask (all my physicians) if fosamax is contraindicated with sacrcoidosis, I get: "I don't know, I am not a sarcoids expert." So-- what say ye????	2014-12-05 12:32:36
QUESTION TRIGGER FINGER	I have two trigger fingers and took Fosamax for several years	2014-12-19 17:28:33
QUESTION MYELODYSPLASTIC SYNDROME	My mum took Fos for many years and her bone density kept getting worse. A year ago she stopped it and eversince there has been a remarkable improvement in bone density. However, sadly she has been diagnosed with MDS - which was the reason why she stopped taking the Fos. Weight bearing exercise and proper nutrition is key. Also hysterectomies are so wrecklessly recommended by doctors nowadays just to forge a path for the same doctors' future commissions promoting the damned biophosphonates. MDS is a bone marrow condition which leads to leukemia.	2015-02-03 07:50:45
QUESTION MENINGIOMA	I took Fosomax for 10 years. I have 2 meningiomas. Should I take Prolia for osteoporosis? Will this drug make my meningiomas grow?	2015-02-06 04:46:12
QUESTION BILE DUCT CANCER	My Dad was taking Alendronic Acid tablets ( 70mg) for 2 years and has recently died of Bile Duct cancer. He would dread taking the 70 mg tablet once per week as it would make him feel so ill and poorly. Is there a link between this drug, ( Fosamax) and Bile Duct cancer. I just want to find out why my dad got cancer.	2015-05-14 04:07:55
QUESTION HYPERLIPIDAEMIA	fiona - Awww twins! So sorry to hear about your injury! I've been cekhcing your blog periodically and was missing seeing your posts. Take care, get well soon and MILK it from your hubby while you can. Wishing you a full recovery from the fracture.	2015-07-13 09:29:14
QUESTION FEMUR FRACTURE	I need either Boniva or prloia. As I have read the side effects of these drugs, I have not thought I should get it. I am glad I read your column today. I would like to know what I can do with supplements and nutrition to heal. Thanks	2015-07-13 10:06:18
QUESTION DYSPEPSIA	Although I'm not a runner, I've been known to push myeslf a little too far in other forms of exercise, just to keep going to finish the end of my workout. that often does lead to something worse, and then i'm completely out for the next day or two. too many ifs lined up (if you did run, if it is a stress fracture, etc.) it could have been way worse.(and I think the doctor really didn't want you to run, but he knows committed athletes sometimes don't listen anyway ) feel better!Heather recently posted..	2015-07-13 18:41:04
QUESTION GASTRITIS	I suffer from chronic gastritis which began when I took fosimax several years ago is it related	2015-07-23 16:47:46
QUESTION MUSCULOSKELETAL PAIN	I get severe cramping	2015-08-02 00:31:14
QUESTION NEUROPATHY PERIPHERAL	can fosamax trigger neuropathy	2015-08-06 12:14:30
QUESTION NEUROPATHY PERIPHERAL	I took fosamax for seven years and now have neuropathy. I do not have diabetes	2015-09-12 16:46:00
QUESTION POLYCYTHAEMIA VERA	I took Fosamax for about 10 years for possible bone fractures. About five years ago I had a blood clot in my left leg and it was found that I had Polycythemia Vera. I have a strong suspection that the Fosamax caused the cancer in my bone marrow.	2015-09-17 12:29:29
QUESTION POLYCYTHAEMIA VERA	I took Fosamax for about 10 years for possible bone fractures. About five years ago I had a blood clot in my left leg and it was found that I had Polycythemia Vera. I have a strong suspicion that Fosamax caused the cancer in my bone marrow.	2015-09-17 12:43:20
QUESTION HEPATIC CYST	Can fosamax cause several small hepatic cysts?	2015-10-15 18:55:38
QUESTION SPLENIC GRANULOMA	Can fosamax cause hepatic cysts?	2015-10-21 10:29:04
QUESTION HIATUS HERNIA	What are the statistics relating to hiatal hernia and long time users of fosomax?	2015-11-11 14:25:07
QUESTION ENDOMETRIAL HYPERPLASIA	Can a person taking fosamax for five years or more develop endometrial Hyperplasia from taking the drug?	2015-12-03 10:36:50
QUESTION ANXIETY	Can fosamax cause anixiet/panic attacks?	2015-12-27 19:13:04
QUESTION BLADDER PAIN	can fosamax cause bladder pain without uti	2016-02-21 08:57:00
QUESTION RED BLOOD CELL COUNT INCREASED	Has any one been diagnosed with high red blood cells from taking fosomax?	2016-02-28 22:41:12
QUESTION EAR PAIN	I have ear pain caused by Fosamax. Will this subside with time as I'm off of it?	2016-03-02 10:34:51
QUESTION OVARIAN CANCER METASTATIC	My mother was diagnosed and died from ovarian cancer. She also was taking Fosomax for osteoporosis. After her diagnosis, she told me that she did not have any problems until she started taking Fosomax. Does taking Fosomax increase the chances of developing ovarian cancer? There is no cancer in my family.	2016-03-02 16:17:32
QUESTION MYELODYSPLASTIC SYNDROME	I was diagnosed with MDS IN October. I am scheduled for my third Prolia injection in April. Should I continue the Prolia? I previously took Fosamax for several years and had two years of Forteo injections	2016-03-07 10:03:56
QUESTION GLAUCOMA	Have been on Alendronate Sodium for 2 years. My entire family has been dx with Glaucoma. Should I be concerned.	2016-04-04 12:16:44
QUESTION IDIOPATHIC PULMONARY FIBROSIS	Can Prolia cause pulmonary fibrosis.	2016-05-04 20:29:14
QUESTION MYELOPROLIFERATIVE DISORDER	My daughter has Osteogenesis Imperfecta Type 1. Has Taken Fosamax on and off for the past 13 years. She may have Myeloproliferative Disease. Has not been confirmed yet. Is there a connection here.	2016-06-07 17:48:43
QUESTION SUDDEN HEARING LOSS	I've been on Alondronate for 8 weeks. I have hearing loss now. Is it the side effects of the medicine?	2016-06-26 12:40:09
CONCERN GASTROOESOPHAGEAL REFLUX DISEASE	i took fosomax for about 6 weeks. During that time I had 2 episodes of severe projectile vomiting with huge amounts of acid. My throat felt like it was closing as well. Once I stopped the fosomax it took 5 months to clear gastro and esophageal symptoms but at present somewhat back to normal. Although I think my acid reflux disorder was absolutely caused by the fosomax and that remains an issue.	2016-07-04 09:22:45
QUESTION BALANCE DISORDER	Great post. This was especially helpful to me. I think both the &#r2m0;pa8anor2al” term and the “urban” term is misleading so it is hard to figure out. Personally, they seem so similar to me that it seems like they can be one genre. I guess the distinction is helpful when you aren’t big on romance.	2016-07-24 04:08:07
QUESTION PANCREATITIS VIRAL	I have recently been diagnosed with pancreatitis. I went to the Emergency room thinking I was having a heart attack(jaw pain,severe shoulder pain and some left arm pain. I am 71 years old and after the doctor checked my blood work, etc. she said I wasn't having a heart attack and decided to run more blood work. I was then told my lipase and amylase levels were elevated. They thought I had alcohol issues, but I told them I have 1 drink a week when I go out to dinner on Friday nights with my girlfriends. They did an ultrasound endoscopy and I have an abundance of calcium deposits in the tail of my pancreas that has been there for quite awhile. The only thing I can think of is the fosamax plus D I took for 5 years and told my doctor that I heard women were breaking bones who were talking it. They are telling me they are not sure what caused it. At this point there are no ducts blocked or stones. Has anyone ever heard of a connection between fosamax plus D and pancreatitis.	2016-08-22 20:59:25
QUESTION GRANULOMA ANNULARE	I started Fosamax in July 2015 and within a month stated developing granuloma annulare.... Any relation?	2016-08-24 06:53:54
QUESTION TINNITUS	It may be random, but I began taking Fosamax about 2 months ago and not long thereafter developed tinnitus. Is there a connection established at this point between the two?	2016-09-07 13:46:32
QUESTION ARTHRITIS	My finger & toes swelling like a sausage, heart burn and severe joint pain. May I know what is the reasons or causes of side effects to mentioned problem?	2016-09-18 09:51:30
QUESTION TINNITUS	I recently got tinnitus and dr prescribed temazepan and alprazolam which is best for sleep/anxiety attacks, thank you JA	2016-10-12 22:39:30
QUESTION GLAUCOMA	Due to a narrow angle glaucoma attack, cataract surgery was performed, but not because of cataracts. Now I have been given a prescription for fosamax for osteoporosis. I am not sure if this will cause more harm than good. Any anyone experienced anything like this?	2016-12-27 13:15:35
QUESTION SYNOVIAL CYST	A large synovial cyst was removed from my cauda equine 2010. In the hospital the night before surgery I went into atrial fibrillation for the first time. I am a cardiologist and felt the rhythm change and asked the nurse to please do an EKG which confirmed I was in atrial fibrillation. I have had femoral neck fractures bilaterally in last 3 years. Can this all be related to 15 year use of Fosamax stopping in 2009?	2017-01-11 17:27:25
QUESTION DIABETIC GASTROPARESIS	Should I take my Erythromycin when I take my Fosamax tablet so the Fosamax with empty my tummy. I take the Erythromycin so my tummy will empty	2017-01-28 11:05:40
QUESTION HYPOPARATHYROIDISM	Can taking Flosamax cause Hypoparathroidism? MY PTH recently came back low and I am seeing an Endocrinologist this week. I have been on Flosamax for 32 months...just about 2- 3/4 years. I have had not any neck surgery or injury and I am 59 years old.	2017-02-05 13:59:28
QUESTION IMMUNE SYSTEM DISORDER	I have been plagued with infections since starting foxamax dec of 2015--1 uti and numerous sinus colds and infections that linger for weeks-- basically sick from thanksgiving through the month of January-- now feb 8th I'm sick in bad again. Wondering if the foxamax could be part of my problem? I have been prone to sinus colds in the past, but not like this.	2017-02-09 20:24:41
QUESTION RIB FRACTURE	Free knowledge like this doesn't just help, it promote dercamocy. Thank you.	2017-03-20 06:51:18
QUESTION DEPRESSION	# cukierki tak, ale jednak parada na Reyes jest o niebo ciekawsza, bo jednak przebrane orszaki 3 reyes robia wieksze wrazenie. Ale i tak bylo fajnie, to taka tradycja ograniczona chyba tylko do Barcelony i nie jest zbyt popularna, ale dzieki mojej katalonskiej kolezance z parcy ja odkrylam. jakby sie uprzec kazdego miesiaca w kadym regionie mozna by w jakims swiecie ucszztniceyc. pozdrawiam	2017-03-20 07:10:10
QUESTION INSOMNIA	you got noted an appealing plus they pretty posting. i’m keen on that person very much. I can not really delniitefy have recorded it finer. I end up as at twitter and youtube my warm credit report and give back again. thanks a lot and all best.	2017-03-20 07:30:22
QUESTION DEPRESSION	I don’t want to hurt you Stn.sien&nbep; I just wondered why the kid was so cross-eyed creepy.  And Alan Ladd was fine, he just didn’t turn human until he became a baddass.  As the goody two-shoes, he kind of fell flat.  Great hair, though.	2017-03-20 08:40:29
QUESTION BRONCHITIS	Santorum Should be running for Pope not POTUS. He comes across whiny and self absorbed and got shellacked in 2006. Guys like Santorum is why so many people will not vote Republican. We do not need social coreanvstive scolds and bitchers.	2017-03-20 08:43:17
QUESTION FATIGUE	Correctif :« atteint 39771 Md de $ fin 2010 soit 269 Md de $&qanp;»es&lbnuo; atteint 39771 Md de $ fin 2010 soit 269 % du PIB »de mÃªme une phrase plus bas : « les 61809 Md de $, soit 419 Md de $ »Merci pour vos analyses	2017-03-20 08:51:35
QUESTION PARAESTHESIA	&qtH-;Bawwwuoawww everybody play along at home...Did you hear there was a fire at the Jared Taylor memorial library last week? Burnt up all 9 of the books, and 6 weren't even colored in yet!"- The wise latinos will never have this problem- all of their great literature is spread across the walls of inner-city buildings from coast to coast.	2017-03-20 08:53:36
QUESTION LUMBAR SPINAL STENOSIS	I began to feel nerve pain in my legs, thighs about a month after I began to take Fosamax. I already had some spinal stenosis, but little nerve pain. Is this just a coincidence? The nerve pain in my legs affects my walking significantly.	2017-04-17 21:40:42
QUESTION MULTIPLE MYELOMA	Why do doctors prescribe this posion call Fosamax?	2017-04-26 21:19:58
QUESTION SUDDEN HEARING LOSS	Recently as in 6-8 weeks after starting fosamax I have a constant sound of my heartbeat in my one ear..I lost my ear about 10 years ago due to similar symptoms from meniers' disease Gss in Kc	2017-05-09 13:02:38

My Patient Resources

Get your questions answered! Over one million patients, researchers, and health care providers have visited FactMed. If you have a question about GASTROINTESTINAL NECROSIS and FOSAMAX, post it here. You may receive a response from a fellow patient - or a leading expert in the field.

Your Question:

Share your experience: Over one million patients, researchers, and health care providers have visited FactMed. If you have a noteworthy experience as a patient taking FOSAMAX, post it here. Your story could help a fellow patient - or provide insight to a leading expert in the field.

Your Experience or Concern:

Telemedicine Expert Consults FactMed newest feature allows patients to consult - via realtime videoconferencing - experts in FOSAMAX. This premium feature connects patients to experts, regardless of geography. FactMed experts charge reasonable rates that may be reimbursable by your insurance as a second-opinion.

We are currently accepting registration for FOSAMAX experts. If you are a healthcare provider experienced in prescribing FOSAMAX, please register here.