About this FactMed analysis covering adverse side effect reports of GLUCOR patients who developed ACANTHOLYSIS.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 2 individuals taking GLUCOR reported ACANTHOLYSIS to the FDA. A total of 323 GLUCOR drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between GLUCOR and ACANTHOLYSIS. In doing so, we compare GLUCOR with other drugs that cause ACANTHOLYSIS, to help you evaluate whether or not GLUCOR causes ACANTHOLYSIS. Likewise, this page shows the most highly-reported side effects of GLUCOR, so you can see if ACANTHOLYSIS ranks among GLUCOR's most well-known side effects.
Summary Statistics
Reports of GLUCOR causing ACANTHOLYSIS: 2
Reports of any side effect of GLUCOR : 323
Percentage of GLUCOR patients where ACANTHOLYSIS is a reported side effect: 0.6192%

FDA reports of any drug causing ACANTHOLYSIS : 33
Average percentage for all medicated patients where ACANTHOLYSIS is reported as a complication: 0.0002%

Physician opinion on GLUCOR as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing GLUCOR:
TYPE 2 DIABETES MELLITUS ( 40 patients )
DIABETES MELLITUS ( 40 patients )
DRUG USE FOR UNKNOWN INDICATION ( 24 patients )
DIABETES MELLITUS NON-INSULIN-DEPENDENT ( 16 patients )
UNEVALUABLE EVENT ( 7 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 6 patients )
ILL-DEFINED DISORDER ( 4 patients )
DIABETES MELLITUS INADEQUATE CONTROL ( 2 patients )
HYPERGLYCAEMIA ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with ACANTHOLYSIS:

AMBIEN (10 patients)
ABRAXANE (9 patients)
ACIPHEX (9 patients)
AMPICILLIN (9 patients)
ASPIRIN (9 patients)
ATIVAN (9 patients)
AVASTIN (9 patients)
CYMBALTA (9 patients)
LEVOTHYROXINE SODIUM (9 patients)
NORCO (9 patients)
RADIATION (9 patients)
VICODIN (9 patients)
XELODA (9 patients)
ZOLOFT (9 patients)
ZOMETA (9 patients)
ZOFRAN (8 patients)
ARANESP (7 patients)
CAPECITABINE (7 patients)
CEFTRIAXONE (7 patients)
CEPHALEXIN (7 patients)
CIPROFLOXACIN (7 patients)
COLACE (7 patients)
DILAUDID (7 patients)
DOXIL (7 patients)
FEMARA (7 patients)
HYDROCODONE BITARTRATE AND ACETAMINOPHEN (7 patients)
KEFLEX (7 patients)
LASIX (7 patients)
LORAZEPAM (7 patients)
NAPROSYN (7 patients)
NEULASTA (7 patients)
NIACIN (7 patients)
PERCOCET (7 patients)
PROVIGIL (7 patients)
RITALIN (7 patients)
SYNTHROID (7 patients)
TAXOTERE (7 patients)
VANCOMYCIN (7 patients)
VANCOMYCIN HCL (7 patients)
DEXAMETHASONE (6 patients)
FENTANYL (6 patients)
CYCLOSPORINE (4 patients)
PLAVIX (4 patients)
RELAFEN (4 patients)
ACETYLSALICYLIC ACID SRT (3 patients)
ACYCLOVIR (3 patients)
AMITIZA (3 patients)
NABUMETONE (3 patients)
NEXIUM (3 patients)
NIFEDIPINE (3 patients)
XIFAXAN (3 patients)
ALDACTAZIDE (2 patients)
AMLOR (2 patients)
AZATHIOPRINE (2 patients)
CLINDAMYCIN (2 patients)
COZAAR (2 patients)
DEPAKENE (2 patients)
DEPAS (2 patients)
DIGOXIN (2 patients)
DIPYRIDAMOL (2 patients)
EMPYNASE (2 patients)
ENALAPRIL MALEATE (2 patients)
ETRETINATE (2 patients)
FRACTAL (2 patients)
FUCIDIN CREAM (2 patients)
FUROSEMIDE (2 patients)
GAMUNEX (2 patients)
GLUCOR (2 patients)
HALCION (2 patients)
ISOSORBIDE MONONITRATE (2 patients)
LAMICTAL (2 patients)
LAXOBERON (2 patients)
LEVEMIR (2 patients)
MAGLAX (2 patients)
METHYLPREDNISOLONE (2 patients)
MINOCYCLIN (2 patients)
MOPRAL (2 patients)
MORPHINE (2 patients)
NITROGLYCERIN (2 patients)
PREDNISOLONE (2 patients)
PREDNISONE (2 patients)
SECTRAL (2 patients)
STILNOX (2 patients)
THEOPHYLLINE (2 patients)
TOPICAL ANTISEPTICS (2 patients)
ACENOCOUMAROL (1 patients)
ACENOCOUMAROL (ACENOCOUMAROL) (1 patients)
ACTIFED (1 patients)
AMILORIDE (1 patients)
AMILORIDE (AMILORIDE HYDROCHLORIDE) (1 patients)
ARNESP (1 patients)
ATENOLOL (1 patients)
ATORVASTATIN CALCIUM (1 patients)
BEMYLID (1 patients)
BETAMETHASONE DIPROPIIONATE (1 patients)
BETAMETHASONE DIPROPIONATE (1 patients)
CARBAMAZEPINE (1 patients)
CEFIXIME (1 patients)
CILAZAPRIL (1 patients)
CIPROFLOXACIN HCL (1 patients)
CIPROFLOXACIN IV (1 patients)
CISPLATIN (1 patients)
COPEGUS (1 patients)
DEXAMETHASONE ACETATE (1 patients)
DOXIUM (CALCIUM DOBESILATE) (1 patients)
ETHYOL (1 patients)
ETOPOSIDE (1 patients)
FENTANYL-100 (1 patients)
FILGRASTIM (FILGRASTIM) (1 patients)
FINASTERIDE (1 patients)
GEMZAR (1 patients)
GLIBENCLAMIDE (1 patients)
GLIMEPIRIDE (1 patients)
HEMERAN GEL (HEPARINOID) (1 patients)
HUMAN INSULIN (1 patients)
INSULIN ACTRAPID HUMAN (1 patients)
INTRON A (1 patients)
IRINOTECAN HCL (1 patients)
L-THYROXIN (1 patients)
LACIDIPINE (1 patients)
LACIDIPINE (LACIDIPINE) (1 patients)
MAGNESIUM OXIDE (MAGNESIUM OXIDE) (1 patients)
METHOTREXATE (1 patients)
MS CONTIN (1 patients)
OXYCODONE HCL (1 patients)
PEG-INTRON (1 patients)
PHENYTOIN (1 patients)
PRAVASTATIN (1 patients)
PRAVASTATIN SODIUM (1 patients)
PREDNISONE TAB (1 patients)
RADIATION THERAPY (1 patients)
REBETOL (1 patients)
RIBAVIRIN (1 patients)
TAREG (1 patients)
TOPICAL MEDICATIONS (FOR PSORIASIS) (1 patients)
ZETIA (1 patients)
Most common side effects for patients taking GLUCOR:
RENAL FAILURE ACUTE (42 patients)
DIARRHOEA (26 patients)
LACTIC ACIDOSIS (21 patients)
ANAEMIA (20 patients)
RENAL FAILURE (20 patients)
DYSPNOEA (19 patients)
DRUG INTERACTION (17 patients)
FALL (17 patients)
CARDIO-RESPIRATORY ARREST (16 patients)
HYPOGLYCAEMIA (14 patients)
OEDEMA PERIPHERAL (14 patients)
VOMITING (14 patients)
PYREXIA (12 patients)
CYTOLYTIC HEPATITIS (12 patients)
ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS (11 patients)
WEIGHT INCREASED (11 patients)
WEIGHT DECREASED (11 patients)
SOMNOLENCE (11 patients)
ABDOMINAL PAIN (10 patients)
PRURITUS (10 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (10 patients)
ATRIAL FIBRILLATION (9 patients)
HYPERKALAEMIA (9 patients)
CHOLESTASIS (9 patients)
CONFUSIONAL STATE (9 patients)
THROMBOCYTOPENIA (9 patients)
URINARY RETENTION (9 patients)
HYPOTENSION (9 patients)
HAEMATOMA (9 patients)
OEDEMA (8 patients)
OVERDOSE (8 patients)
DERMATITIS EXFOLIATIVE (8 patients)
DIABETES MELLITUS INADEQUATE CONTROL (8 patients)
VASCULAR PURPURA (8 patients)
HYPONATRAEMIA (8 patients)
LOSS OF CONSCIOUSNESS (8 patients)
EOSINOPHILIA (8 patients)
HEADACHE (7 patients)
RASH PUSTULAR (7 patients)
INFLAMMATION (7 patients)
DECREASED APPETITE (7 patients)
DYSARTHRIA (7 patients)
SEPTIC SHOCK (7 patients)
GINGIVAL BLEEDING (7 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (7 patients)
PANCREATITIS ACUTE (6 patients)
MULTI-ORGAN FAILURE (6 patients)
BLOOD CREATININE INCREASED (6 patients)
HEPATIC STEATOSIS (6 patients)
HAEMOPTYSIS (6 patients)
CARDIAC FAILURE (6 patients)
HYPERTENSION (6 patients)
DEHYDRATION (6 patients)
DYSPHAGIA (6 patients)
MALAISE (6 patients)
METABOLIC ACIDOSIS (6 patients)
ABNORMAL BEHAVIOUR (5 patients)
STERNAL FRACTURE (5 patients)
RESPIRATORY DISTRESS (5 patients)
LEUKOPENIA (5 patients)
AGITATION (5 patients)
AGRANULOCYTOSIS (5 patients)
URTICARIA (5 patients)
LEUKOCYTOSIS (5 patients)
PANCYTOPENIA (5 patients)
BLISTER (5 patients)
HEPATIC ENCEPHALOPATHY (5 patients)
BRADYCARDIA (5 patients)
BRONCHITIS (5 patients)
LICHENOID KERATOSIS (5 patients)
PURPURA (5 patients)
CHOLECYSTITIS ACUTE (5 patients)
RASH PAPULAR (5 patients)
COMA (5 patients)
CONVULSION (5 patients)
CREATININE RENAL CLEARANCE DECREASED (5 patients)
HYPERSENSITIVITY (5 patients)
HYPERTHERMIA (5 patients)
HAEMATURIA (5 patients)
INSOMNIA (5 patients)
DYSPNOEA EXERTIONAL (5 patients)
EXTRAPYRAMIDAL DISORDER (5 patients)
FACE OEDEMA (5 patients)
NEUTROPENIA (5 patients)
METABOLIC DISORDER (5 patients)
PULMONARY OEDEMA (4 patients)
MUSCLE HAEMORRHAGE (4 patients)
ALTERED STATE OF CONSCIOUSNESS (4 patients)
HEPATOMEGALY (4 patients)
ANGIONEUROTIC OEDEMA (4 patients)
LYMPHADENOPATHY (4 patients)
BENIGN PROSTATIC HYPERPLASIA (4 patients)
PULMONARY EMBOLISM (4 patients)
TOXIC SKIN ERUPTION (4 patients)
SUBDURAL HAEMATOMA (4 patients)
TRANSIENT ISCHAEMIC ATTACK (4 patients)
HEART INJURY (4 patients)
INFARCTION (4 patients)
BUNDLE BRANCH BLOCK LEFT (4 patients)
HYPOXIA (4 patients)
CALCULUS URINARY (4 patients)
MYOCARDIAL INFARCTION (4 patients)
MUSCLE ATROPHY (4 patients)
CEREBRAL HAEMORRHAGE (4 patients)
CHEST PAIN (4 patients)
CONDITION AGGRAVATED (4 patients)
SPLENOMEGALY (4 patients)
DEATH (4 patients)
SYNCOPE (4 patients)
HYPERGLYCAEMIA (4 patients)
ERYTHEMA (4 patients)
ACCIDENT (3 patients)
VISUAL IMPAIRMENT (3 patients)
KIDNEY ENLARGEMENT (3 patients)
PULMONARY FIBROSIS (3 patients)
ANTIPSYCHOTIC DRUG LEVEL INCREASED (3 patients)
HYPERAMMONAEMIA (3 patients)
THERAPEUTIC AGENT TOXICITY (3 patients)
VERTIGO (3 patients)
HEPATIC CIRRHOSIS (3 patients)
TROPONIN INCREASED (3 patients)
ASTHENIA (3 patients)
HAEMORRHAGIC STROKE (3 patients)
RECTAL HAEMORRHAGE (3 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (3 patients)
HYPERTRIGLYCERIDAEMIA (3 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (3 patients)
HYPOKALAEMIA (3 patients)
WHEEZING (3 patients)
BLOOD PRESSURE INCREASED (3 patients)
URINARY TRACT INFECTION (3 patients)
LUNG DISORDER (3 patients)
BUNDLE BRANCH BLOCK RIGHT (3 patients)
C-REACTIVE PROTEIN INCREASED (3 patients)
PANCREATITIS (3 patients)
CHEST DISCOMFORT (3 patients)
CHOLELITHIASIS (3 patients)
NERVOUS SYSTEM DISORDER (3 patients)
STAPHYLOCOCCAL INFECTION (3 patients)
STEVENS-JOHNSON SYNDROME (3 patients)
HEPATIC FIBROSIS (3 patients)
HAEMOGLOBIN DECREASED (3 patients)
THROMBOSIS (3 patients)
HYPOCALCAEMIA (3 patients)
HYPOGLYCAEMIC COMA (3 patients)
VENTRICULAR FIBRILLATION (3 patients)
DIABETIC KETOACIDOSIS (3 patients)
DISORIENTATION (3 patients)
DIZZINESS (3 patients)
INFECTED SKIN ULCER (3 patients)
LEUKOCYTOCLASTIC VASCULITIS (3 patients)
DRUG TOXICITY (3 patients)
ELECTROCARDIOGRAM REPOLARISATION ABNORMALITY (3 patients)
LOCKED-IN SYNDROME (3 patients)
FEBRILE BONE MARROW APLASIA (3 patients)
OVARIAN CYST (3 patients)
MENINGORRHAGIA (3 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (3 patients)
ABDOMINAL DISTENSION (2 patients)
IIIRD NERVE PARALYSIS (2 patients)
PERIPHERAL EMBOLISM (2 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (2 patients)
ANURIA (2 patients)
ISCHAEMIC STROKE (2 patients)
INTERNATIONAL NORMALISED RATIO DECREASED (2 patients)
ATRIOVENTRICULAR BLOCK FIRST DEGREE (2 patients)
NECK PAIN (2 patients)
MUCOSAL INFLAMMATION (2 patients)
PERSONALITY CHANGE (2 patients)
PEMPHIGUS (2 patients)
MUSCLE CONTRACTIONS INVOLUNTARY (2 patients)
RALES (2 patients)
MOTOR DYSFUNCTION (2 patients)
BLOOD BILIRUBIN INCREASED (2 patients)
INTERSTITIAL LUNG DISEASE (2 patients)
IMPETIGO (2 patients)
MECHANICAL VENTILATION (2 patients)
BULLOUS LUNG DISEASE (2 patients)
C-REACTIVE PROTEIN ABNORMAL (2 patients)
MYOCARDIAL ISCHAEMIA (2 patients)
PALLOR (2 patients)
PARAESTHESIA (2 patients)
CEREBRAL ATROPHY (2 patients)
MIOSIS (2 patients)
RASH ERYTHEMATOUS (2 patients)
RASH (2 patients)
CHOLANGITIS (2 patients)
PSYCHOMOTOR RETARDATION (2 patients)
RASH MACULO-PAPULAR (2 patients)
COGNITIVE DISORDER (2 patients)
LINEAR IGA DISEASE (2 patients)
LIMB DISCOMFORT (2 patients)
DYSKINESIA (2 patients)
DYSPNOEA AT REST (2 patients)
ECCHYMOSIS (2 patients)
ECZEMA (2 patients)
LEFT VENTRICULAR FAILURE (2 patients)
EXCITABILITY (2 patients)
NAUSEA (2 patients)
EYE SWELLING (2 patients)
FACIAL ASYMMETRY (2 patients)
MUSCULOSKELETAL STIFFNESS (2 patients)
FAECAL INCONTINENCE (2 patients)
FAECES DISCOLOURED (2 patients)
FATIGUE (2 patients)
NON-HODGKIN'S LYMPHOMA (2 patients)
OFF LABEL USE (2 patients)
MUSCULAR WEAKNESS (2 patients)
GAIT DISTURBANCE (2 patients)
GASTROINTESTINAL DISORDER (2 patients)

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