Is RESTLESS LEGS SYNDROME a side effect of HYDROCHLOROTHIAZIDE ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of HYDROCHLOROTHIAZIDE patients who developed RESTLESS LEGS SYNDROME.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 193 individuals taking HYDROCHLOROTHIAZIDE reported RESTLESS LEGS SYNDROME to the FDA. A total of 47981 HYDROCHLOROTHIAZIDE drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between HYDROCHLOROTHIAZIDE and RESTLESS LEGS SYNDROME. In doing so, we compare HYDROCHLOROTHIAZIDE with other drugs that cause RESTLESS LEGS SYNDROME, to help you evaluate whether or not HYDROCHLOROTHIAZIDE causes RESTLESS LEGS SYNDROME. Likewise, this page shows the most highly-reported side effects of HYDROCHLOROTHIAZIDE, so you can see if RESTLESS LEGS SYNDROME ranks among HYDROCHLOROTHIAZIDE's most well-known side effects.

Summary Statistics
Reports of HYDROCHLOROTHIAZIDE causing RESTLESS LEGS SYNDROME: 193
Reports of any side effect of HYDROCHLOROTHIAZIDE : 47981
Percentage of HYDROCHLOROTHIAZIDE patients where RESTLESS LEGS SYNDROME is a reported side effect: 0.4022%

FDA reports of any drug causing RESTLESS LEGS SYNDROME : 5793
Average percentage for all medicated patients where RESTLESS LEGS SYNDROME is reported as a complication: 0.0363%

Physician opinion on HYDROCHLOROTHIAZIDE as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing HYDROCHLOROTHIAZIDE:

HYPERTENSION ( 7832 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 1961 patients )
DRUG USE FOR UNKNOWN INDICATION ( 1797 patients )
BLOOD PRESSURE ( 703 patients )
DIURETIC THERAPY ( 457 patients )
FLUID RETENTION ( 437 patients )
BLOOD PRESSURE ABNORMAL ( 191 patients )
OEDEMA ( 168 patients )
BLOOD PRESSURE INCREASED ( 161 patients )
OEDEMA PERIPHERAL ( 143 patients )
CARDIAC DISORDER ( 83 patients )
SWELLING ( 79 patients )
ESSENTIAL HYPERTENSION ( 78 patients )
ILL-DEFINED DISORDER ( 58 patients )
CARDIAC FAILURE ( 53 patients )
POLYURIA ( 43 patients )
CARDIAC FAILURE CONGESTIVE ( 34 patients )
NEPHROLITHIASIS ( 31 patients )
BLOOD PRESSURE MANAGEMENT ( 30 patients )
JOINT SWELLING ( 23 patients )
PROPHYLAXIS ( 21 patients )
ATRIAL FIBRILLATION ( 18 patients )
CORONARY ARTERY DISEASE ( 15 patients )
HYPOTENSION ( 15 patients )
CARDIOVASCULAR DISORDER ( 12 patients )
NEPHROGENIC DIABETES INSIPIDUS ( 11 patients )
ARTHRITIS ( 11 patients )
MENIERE'S DISEASE ( 10 patients )
DEHYDRATION ( 9 patients )
CARDIAC FAILURE CHRONIC ( 9 patients )
ANTIINFLAMMATORY THERAPY ( 8 patients )
URINE CALCIUM ( 8 patients )
RENAL CELL CARCINOMA ( 8 patients )
BRONCHOPULMONARY DYSPLASIA ( 8 patients )
RHEUMATOID ARTHRITIS ( 8 patients )
MYELODYSPLASTIC SYNDROME ( 7 patients )
MYOCARDIAL INFARCTION ( 6 patients )
PULMONARY HYPERTENSION ( 6 patients )
LYMPHOEDEMA ( 6 patients )
CORONARY ARTERY SURGERY ( 6 patients )
FLUID IMBALANCE ( 6 patients )
RENAL FAILURE ( 6 patients )
PAIN ( 5 patients )
PANCREATITIS ( 5 patients )
DIABETES MELLITUS ( 5 patients )
SUICIDE ATTEMPT ( 5 patients )
HYPERTONIA ( 5 patients )
WEIGHT DECREASED ( 5 patients )
BLOOD CHOLESTEROL INCREASED ( 5 patients )
INTENTIONAL OVERDOSE ( 5 patients )
RENAL DISORDER ( 4 patients )
COMPLETED SUICIDE ( 4 patients )
WEIGHT CONTROL ( 4 patients )
THYROID DISORDER ( 4 patients )
INNER EAR DISORDER ( 4 patients )
MICTURITION DISORDER ( 4 patients )
OSTEOPOROSIS ( 4 patients )
PLEURAL EFFUSION ( 4 patients )
RENAL FAILURE CHRONIC ( 4 patients )
HYPERCHOLESTEROLAEMIA ( 4 patients )
DIABETES INSIPIDUS ( 4 patients )
HYPERTENSIVE HEART DISEASE ( 3 patients )
HEADACHE ( 3 patients )
CALCINOSIS ( 3 patients )
EYE SWELLING ( 3 patients )
PULMONARY ARTERIAL HYPERTENSION ( 3 patients )
BLOOD PRESSURE DECREASED ( 3 patients )
PANCREATIC CARCINOMA ( 3 patients )
BLOOD PRESSURE INADEQUATELY CONTROLLED ( 3 patients )
DIZZINESS ( 3 patients )
GENERALISED OEDEMA ( 3 patients )
ABDOMINAL DISTENSION ( 3 patients )
DRUG THERAPY ( 3 patients )
HYPOPARATHYROIDISM ( 3 patients )
ACCIDENTAL EXPOSURE ( 3 patients )
TRANSIENT ISCHAEMIC ATTACK ( 3 patients )
HYPERKALAEMIA ( 3 patients )
ANXIETY ( 3 patients )
SEPSIS ( 3 patients )
PSORIATIC ARTHROPATHY ( 2 patients )
FLUID OVERLOAD ( 2 patients )
VASCULITIS ( 2 patients )
BLOOD PRESSURE FLUCTUATION ( 2 patients )
VERTIGO ( 2 patients )
TACHYCARDIA ( 2 patients )
HYPONATRAEMIA ( 2 patients )
RENAL HYPERTENSION ( 2 patients )
DYSPNOEA ( 2 patients )
HYPERCALCIURIA ( 2 patients )
PORTAL HYPERTENSION ( 2 patients )
HYPOTHYROIDISM ( 2 patients )
URINARY RETENTION ( 2 patients )
ORTHOSTATIC HYPOTENSION ( 2 patients )
RENOVASCULAR HYPERTENSION ( 2 patients )
ISCHAEMIC HEART DISEASE PROPHYLAXIS ( 2 patients )
ROUTINE HEALTH MAINTENANCE ( 2 patients )
AORTIC STENOSIS ( 2 patients )
LEFT VENTRICULAR DYSFUNCTION ( 2 patients )
VENOUS INSUFFICIENCY ( 2 patients )
NEPHROTIC SYNDROME ( 2 patients )
CONGESTIVE CARDIOMYOPATHY ( 2 patients )
BLOOD CHOLESTEROL ( 2 patients )
RENAL IMPAIRMENT ( 2 patients )
UNEVALUABLE EVENT ( 2 patients )
MENSTRUAL DISORDER ( 2 patients )
PREMEDICATION ( 2 patients )
DEMENTIA ( 2 patients )
OSTEOARTHRITIS ( 2 patients )
URINE ABNORMALITY ( 2 patients )
CARDIOMYOPATHY ( 2 patients )
MULTIPLE DRUG OVERDOSE ( 1 patients )
UTERINE LEIOMYOMA ( 1 patients )
DIABETIC CARDIOMYOPATHY ( 1 patients )
LEFT VENTRICULAR HYPERTROPHY ( 1 patients )
SUICIDAL IDEATION ( 1 patients )
ATRIAL TACHYCARDIA ( 1 patients )
CARDIOVASCULAR INSUFFICIENCY ( 1 patients )
LOCALISED OEDEMA ( 1 patients )
BENIGN PROSTATIC HYPERPLASIA ( 1 patients )
CEREBROVASCULAR ACCIDENT PROPHYLAXIS ( 1 patients )
HYPOALDOSTERONISM ( 1 patients )
DRUG EXPOSURE DURING PREGNANCY ( 1 patients )
PHYSICAL EXAMINATION ( 1 patients )
BLISTER ( 1 patients )
NEUROPATHY PERIPHERAL ( 1 patients )
RENAL FAILURE ACUTE ( 1 patients )
ABDOMINAL PAIN ( 1 patients )
BRADYCARDIA ( 1 patients )
DRUG TOXICITY ( 1 patients )
HEPATITIS CHRONIC ACTIVE ( 1 patients )
MALIGNANT HYPERTENSION ( 1 patients )
PNEUMONIA ( 1 patients )
BLOOD CALCIUM DECREASED ( 1 patients )
CORONARY ARTERY BYPASS ( 1 patients )
HYPOPHOSPHATASIA ( 1 patients )
OBSESSIVE-COMPULSIVE DISORDER ( 1 patients )
WEIGHT INCREASED ( 1 patients )
ACCIDENTAL OVERDOSE ( 1 patients )
MATERNAL EXPOSURE DURING PREGNANCY ( 1 patients )
TYPE 2 DIABETES MELLITUS ( 1 patients )
BLOOD CHOLESTEROL ABNORMAL ( 1 patients )
OEDEMA DUE TO CARDIAC DISEASE ( 1 patients )
RENAL TUBULAR ACIDOSIS ( 1 patients )
ADVERSE DRUG REACTION ( 1 patients )
EAR DISORDER ( 1 patients )
HYPERINSULINISM ( 1 patients )
MENSTRUAL CYCLE MANAGEMENT ( 1 patients )
PREGNANCY INDUCED HYPERTENSION ( 1 patients )
BLOOD DISORDER ( 1 patients )
EPILEPSY ( 1 patients )
HYPERNATRAEMIA ( 1 patients )
URINARY TRACT DISORDER ( 1 patients )
BLOOD PH NORMAL ( 1 patients )
DEPRESSION ( 1 patients )
OSTEOMYELITIS ( 1 patients )
CARDIOMEGALY ( 1 patients )
HYPERPARATHYROIDISM PRIMARY ( 1 patients )
MITRAL VALVE PROLAPSE ( 1 patients )
PROTEINURIA ( 1 patients )
SPINAL DISORDER ( 1 patients )
HYPERTENSIVE CARDIOMYOPATHY ( 1 patients )
VASCULAR GRAFT ( 1 patients )
DIURETIC EFFECT ( 1 patients )
LIMB DISCOMFORT ( 1 patients )
BACK PAIN ( 1 patients )
CEREBROVASCULAR ACCIDENT ( 1 patients )
FLUID REPLACEMENT ( 1 patients )
LUNG DISORDER ( 1 patients )
PERIPHERAL VASCULAR DISORDER ( 1 patients )
SYSTOLIC HYPERTENSION ( 1 patients )
BLADDER OPERATION ( 1 patients )
CHEST DISCOMFORT ( 1 patients )
HYPOKALAEMIA ( 1 patients )
WATER INTOXICATION ( 1 patients )
LYMPHOMA ( 1 patients )
THERAPEUTIC ASPIRATION ( 1 patients )
BLOOD CALCIUM ABNORMAL ( 1 patients )
HEART RATE IRREGULAR ( 1 patients )
OBESITY ( 1 patients )
HIDRADENITIS ( 1 patients )
MATERNAL DRUGS AFFECTING FOETUS ( 1 patients )
WEIGHT LOSS DIET ( 1 patients )
ACNE ( 1 patients )
DYSURIA ( 1 patients )
PRE-EXISTING DISEASE ( 1 patients )
DEEP VEIN THROMBOSIS ( 1 patients )
RENAL TUBULAR NECROSIS ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
ELECTROLYTE IMBALANCE ( 1 patients )
URINARY SEDIMENT PRESENT ( 1 patients )
BLOOD GLUCOSE FLUCTUATION ( 1 patients )
CARDIAC FIBRILLATION ( 1 patients )
HYPERPARATHYROIDISM ( 1 patients )
MIGRAINE ( 1 patients )
BLOOD POTASSIUM INCREASED ( 1 patients )
OSTEOPENIA ( 1 patients )
FIBROMYALGIA ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with RESTLESS LEGS SYNDROME:

FOSAMAX (1526 patients)
SEROQUEL (935 patients)
METOCLOPRAMIDE (756 patients)
VIOXX (609 patients)
REQUIP (516 patients)
ASPIRIN (439 patients)
LIPITOR (346 patients)
CYMBALTA (320 patients)
LASIX (311 patients)
REGLAN (305 patients)
ZOMETA (303 patients)
NEXIUM (301 patients)
NEURONTIN (293 patients)
XANAX (276 patients)
AMBIEN (266 patients)
COUMADIN (263 patients)
MIRAPEX (260 patients)
SYNTHROID (241 patients)
CLONAZEPAM (220 patients)
LEXAPRO (215 patients)
LISINOPRIL (212 patients)
ZOLOFT (209 patients)
LYRICA (204 patients)
CHANTIX (199 patients)
KLONOPIN (198 patients)
PRILOSEC (198 patients)
AVONEX (196 patients)
FUROSEMIDE (195 patients)
DURAGESIC-100 (193 patients)
HYDROCHLOROTHIAZIDE (193 patients)
PREDNISONE (191 patients)
EFFEXOR (186 patients)
RISPERDAL (185 patients)
LORAZEPAM (184 patients)
ALENDRONATE SODIUM (181 patients)
METOCLOPRAMIDE HYDROCHLORIDE (179 patients)
ALBUTEROL (177 patients)
MIRTAZAPINE (174 patients)
ATIVAN (171 patients)
PAXIL (170 patients)
PROTONIX (168 patients)
CELEBREX (168 patients)
AREDIA (166 patients)
PERCOCET (162 patients)
ZOCOR (159 patients)
ATENOLOL (153 patients)
OMNISCAN (152 patients)
GABAPENTIN (152 patients)
PREVACID (150 patients)
CRESTOR (149 patients)
LORTAB (148 patients)
EFFEXOR XR (148 patients)
IBUPROFEN (145 patients)
PROZAC (144 patients)
LEVOTHYROXINE SODIUM (144 patients)
ACETAMINOPHEN (143 patients)
ZYPREXA (141 patients)
FOSAMAX PLUS D (141 patients)
PREMARIN (140 patients)
AMITRIPTYLINE HCL (139 patients)
TRAZODONE HCL (136 patients)
ADVAIR DISKUS 100/50 (136 patients)
VICODIN (136 patients)
NORVASC (135 patients)
PLAVIX (132 patients)
HEPARIN SODIUM INJECTION (130 patients)
CELEXA (128 patients)
SINGULAIR (127 patients)
FORTEO (126 patients)
MORPHINE (124 patients)
TOPROL-XL (123 patients)
WELLBUTRIN (123 patients)
OXYCONTIN (121 patients)
OMEPRAZOLE (121 patients)
ABILIFY (114 patients)
GEODON (112 patients)
LEVAQUIN (111 patients)
SIMVASTATIN (108 patients)
CALCIUM (UNSPECIFIED) (106 patients)
FOLIC ACID (106 patients)
HUMIRA (105 patients)
TYSABRI (105 patients)
SPIRIVA (104 patients)
SPIRONOLACTONE (104 patients)
ZOFRAN (103 patients)
DIOVAN (103 patients)
VITAMIN D (103 patients)
ENBREL (102 patients)
POTASSIUM CHLORIDE (102 patients)
DIAZEPAM (100 patients)
VALIUM (99 patients)
METFORMIN HCL (95 patients)
TRAMADOL HCL (94 patients)
FLONASE (91 patients)
FLEXERIL (89 patients)
ALPRAZOLAM (89 patients)
DEPAKOTE (88 patients)
CITALOPRAM HYDROBROMIDE (87 patients)
TOPAMAX (87 patients)
COZAAR (86 patients)
ALLEGRA (86 patients)
ZANTAC (85 patients)
OXYCODONE HCL (83 patients)
ZYRTEC (83 patients)
RESTORIL (82 patients)
FENTANYL (81 patients)
PROMETHAZINE (80 patients)
LAMICTAL (79 patients)
DIGOXIN (78 patients)
BONIVA (78 patients)
ZETIA (78 patients)
SEROQUEL XR (76 patients)
VITAMIN B-12 (76 patients)
LOVENOX (76 patients)
REMICADE (76 patients)
ALLOPURINOL (76 patients)
AMLODIPINE (76 patients)
LANTUS (75 patients)
ZITHROMAX (74 patients)
ACTONEL (74 patients)
COMPAZINE (73 patients)
IRON (73 patients)
ACIPHEX (72 patients)
CLARITIN (70 patients)
ELAVIL (69 patients)
RISPERDAL CONSTA (69 patients)
VITAMINS (UNSPECIFIED) (68 patients)
FLUOXETINE (68 patients)
MULTI-VITAMIN (68 patients)
PRISTIQ (67 patients)
METHOTREXATE (67 patients)
CALCIUM (67 patients)
ACYCLOVIR (65 patients)
COLACE (65 patients)
METOPROLOL TARTRATE (64 patients)
SINEMET (64 patients)
SOLIRIS (63 patients)
PEPCID (63 patients)
AMOXICILLIN (63 patients)
PREDNISONE TAB (61 patients)
HALDOL (61 patients)
ASCORBIC ACID (61 patients)
POTASSIUM (60 patients)
ULTRAM (59 patients)
GLUCOPHAGE (59 patients)
LUNESTA (59 patients)
ROPINIROLE (58 patients)
HUMALOG (58 patients)
INSULIN (58 patients)
WARFARIN SODIUM (57 patients)
ACTOS (57 patients)
COREG (57 patients)
OLANZAPINE (57 patients)
DECADRON (57 patients)
VITAMIN E (56 patients)
LEVOXYL (56 patients)
SAPHRIS (56 patients)
ALTACE (56 patients)
[THERAPY UNSPECIFIED] (55 patients)
MULTI-VITAMINS (55 patients)
FLOMAX (54 patients)
CIPROFLOXACIN (54 patients)
PERIDEX (54 patients)
TAMOXIFEN CITRATE (54 patients)
BENADRYL (53 patients)
REMERON (53 patients)
BEXTRA (53 patients)
NITROGLYCERIN (53 patients)
BACLOFEN (53 patients)
DEXAMETHASONE (53 patients)
KLOR-CON (53 patients)
MOTRIN (52 patients)
VERAPAMIL (51 patients)
FENTANYL-100 (51 patients)
TRICOR (51 patients)
SOMA (51 patients)
FLAGYL (51 patients)
LANSOPRAZOLE (51 patients)
NIASPAN (50 patients)
LIDOCAINE (50 patients)
PAROXETINE HCL (50 patients)
DOXYCYCLINE (50 patients)
CHLORHEXIDINE GLUCONATE (50 patients)
TRAZODONE HYDROCHLORIDE (49 patients)
LITHIUM CARBONATE (49 patients)
HYDROCODONE (49 patients)
PHENERGAN (48 patients)
NASONEX (48 patients)
HYDROCODONE BITARTRATE (48 patients)
PROPRANOLOL (47 patients)
TAXOTERE (47 patients)
VITAMIN D (UNSPECIFIED) (47 patients)
TYLENOL-500 (47 patients)
HEPARIN (46 patients)
FISH OIL (46 patients)
DARVOCET-N 100 (46 patients)
FEMARA (46 patients)
RIBAVIRIN (45 patients)
CLOZARIL (45 patients)
GLUCOSAMINE (45 patients)
TYLENOL (45 patients)
SKELAXIN (45 patients)
REBIF (44 patients)
GLYBURIDE (44 patients)
K-DUR (43 patients)
PRAVASTATIN (43 patients)
TEGRETOL (43 patients)
AVELOX (43 patients)
NYSTATIN (43 patients)
PREDNISOLONE (43 patients)

Most common side effects for patients taking HYDROCHLOROTHIAZIDE:

NAUSEA (3850 patients)
DYSPNOEA (3317 patients)
PAIN (3202 patients)
DIZZINESS (3080 patients)
FATIGUE (3043 patients)
DIARRHOEA (2606 patients)
ASTHENIA (2483 patients)
HEADACHE (2423 patients)
HYPERTENSION (2411 patients)
ANXIETY (2410 patients)
DRUG INEFFECTIVE (2353 patients)
VOMITING (2319 patients)
FALL (2156 patients)
OEDEMA PERIPHERAL (2096 patients)
ARTHRALGIA (1948 patients)
CHEST PAIN (1925 patients)
DEPRESSION (1877 patients)
BACK PAIN (1840 patients)
PAIN IN EXTREMITY (1832 patients)
ANAEMIA (1672 patients)
MYOCARDIAL INFARCTION (1661 patients)
WEIGHT DECREASED (1632 patients)
HYPOTENSION (1617 patients)
PNEUMONIA (1597 patients)
BLOOD PRESSURE INCREASED (1541 patients)
CEREBROVASCULAR ACCIDENT (1535 patients)
DEHYDRATION (1517 patients)
INSOMNIA (1445 patients)
ABDOMINAL PAIN (1432 patients)
COUGH (1432 patients)
RENAL FAILURE ACUTE (1426 patients)
RENAL FAILURE (1410 patients)
PYREXIA (1378 patients)
BLOOD GLUCOSE INCREASED (1307 patients)
INJURY (1286 patients)
MALAISE (1268 patients)
WEIGHT INCREASED (1265 patients)
CONSTIPATION (1249 patients)
PRURITUS (1173 patients)
RASH (1172 patients)
CARDIAC FAILURE CONGESTIVE (1168 patients)
ATRIAL FIBRILLATION (1158 patients)
HYPOAESTHESIA (1099 patients)
MYALGIA (1069 patients)
SYNCOPE (1057 patients)
MUSCLE SPASMS (1055 patients)
CONFUSIONAL STATE (1043 patients)
DIABETES MELLITUS (1043 patients)
PARAESTHESIA (1034 patients)
URINARY TRACT INFECTION (1009 patients)
FEELING ABNORMAL (1001 patients)
GAIT DISTURBANCE (998 patients)
SOMNOLENCE (974 patients)
FLUSHING (972 patients)
ABDOMINAL PAIN UPPER (952 patients)
HYPOKALAEMIA (931 patients)
DECREASED APPETITE (927 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (894 patients)
EMOTIONAL DISTRESS (876 patients)
OSTEOARTHRITIS (874 patients)
HYPERHIDROSIS (869 patients)
HYPONATRAEMIA (864 patients)
DRUG INTERACTION (863 patients)
TREMOR (859 patients)
CORONARY ARTERY DISEASE (844 patients)
PALPITATIONS (829 patients)
DEATH (820 patients)
LOSS OF CONSCIOUSNESS (814 patients)
PULMONARY EMBOLISM (806 patients)
VISION BLURRED (801 patients)
CONDITION AGGRAVATED (793 patients)
BLOOD CREATININE INCREASED (786 patients)
BLOOD CHOLESTEROL INCREASED (780 patients)
MUSCULAR WEAKNESS (750 patients)
OSTEONECROSIS OF JAW (744 patients)
PLEURAL EFFUSION (726 patients)
ERYTHEMA (701 patients)
HAEMOGLOBIN DECREASED (700 patients)
CHEST DISCOMFORT (695 patients)
DEEP VEIN THROMBOSIS (679 patients)
CONVULSION (649 patients)
DYSPEPSIA (641 patients)
HEART RATE INCREASED (638 patients)
BONE DISORDER (632 patients)
DYSPHAGIA (620 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (619 patients)
INFECTION (615 patients)
RESPIRATORY FAILURE (614 patients)
NEUROPATHY PERIPHERAL (611 patients)
PANCREATITIS (607 patients)
SINUSITIS (598 patients)
TACHYCARDIA (588 patients)
ANHEDONIA (587 patients)
CHILLS (580 patients)
OSTEOMYELITIS (577 patients)
BRONCHITIS (567 patients)
BRADYCARDIA (565 patients)
TRANSIENT ISCHAEMIC ATTACK (563 patients)
CHOLELITHIASIS (562 patients)
SEPSIS (551 patients)
THROMBOCYTOPENIA (542 patients)
URTICARIA (540 patients)
HYPERSENSITIVITY (537 patients)
CARDIAC DISORDER (537 patients)
TYPE 2 DIABETES MELLITUS (531 patients)
BLOOD POTASSIUM DECREASED (530 patients)
OSTEONECROSIS (530 patients)
JOINT SWELLING (530 patients)
BALANCE DISORDER (524 patients)
SWELLING (521 patients)
ASTHMA (520 patients)
PAIN IN JAW (513 patients)
GASTROINTESTINAL HAEMORRHAGE (511 patients)
HYPOGLYCAEMIA (511 patients)
HYPERLIPIDAEMIA (510 patients)
DRY MOUTH (505 patients)
ABDOMINAL DISCOMFORT (500 patients)
ABDOMINAL DISTENSION (498 patients)
ARTHRITIS (497 patients)
AMNESIA (496 patients)
MUSCULOSKELETAL PAIN (496 patients)
CARDIOMEGALY (494 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (494 patients)
RENAL IMPAIRMENT (490 patients)
MITRAL VALVE INCOMPETENCE (487 patients)
CELLULITIS (485 patients)
CONTUSION (485 patients)
BLOOD PRESSURE DECREASED (484 patients)
ATELECTASIS (471 patients)
IMPAIRED HEALING (469 patients)
DYSGEUSIA (468 patients)
UNEVALUABLE EVENT (463 patients)
MENTAL STATUS CHANGES (462 patients)
MEMORY IMPAIRMENT (462 patients)
HYPERGLYCAEMIA (456 patients)
OEDEMA (446 patients)
SWELLING FACE (446 patients)
INTERVERTEBRAL DISC PROTRUSION (440 patients)
HAEMORRHOIDS (437 patients)
NECK PAIN (435 patients)
STRESS (434 patients)
FEELING HOT (431 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (429 patients)
OSTEOPOROSIS (429 patients)
SPINAL OSTEOARTHRITIS (425 patients)
SUICIDAL IDEATION (425 patients)
NEUTROPENIA (421 patients)
CATARACT (420 patients)
INJECTION SITE PAIN (417 patients)
ALOPECIA (416 patients)
BLOOD UREA INCREASED (411 patients)
LETHARGY (409 patients)
BONE PAIN (407 patients)
RECTAL HAEMORRHAGE (405 patients)
GASTRITIS (403 patients)
ALANINE AMINOTRANSFERASE INCREASED (403 patients)
ARRHYTHMIA (401 patients)
UPPER RESPIRATORY TRACT INFECTION (399 patients)
VERTIGO (399 patients)
FEAR (399 patients)
NEPHROLITHIASIS (397 patients)
ANGINA PECTORIS (393 patients)
NERVOUSNESS (391 patients)
BURNING SENSATION (390 patients)
CARDIAC ARREST (390 patients)
INTERVERTEBRAL DISC DEGENERATION (381 patients)
PHARMACEUTICAL PRODUCT COMPLAINT (380 patients)
DRUG HYPERSENSITIVITY (379 patients)
DYSPNOEA EXERTIONAL (373 patients)
MULTI-ORGAN FAILURE (372 patients)
HOT FLUSH (372 patients)
DEFORMITY (368 patients)
EPISTAXIS (363 patients)
TRICUSPID VALVE INCOMPETENCE (363 patients)
NASOPHARYNGITIS (358 patients)
HAEMATOCHEZIA (357 patients)
THROMBOSIS (357 patients)
TINNITUS (355 patients)
FEMUR FRACTURE (355 patients)
PLATELET COUNT DECREASED (353 patients)
BREAST CANCER (352 patients)
DIVERTICULUM (350 patients)
MUSCULOSKELETAL STIFFNESS (349 patients)
ABASIA (346 patients)
BLOOD TRIGLYCERIDES INCREASED (346 patients)
HYPOTHYROIDISM (341 patients)
INCORRECT DOSE ADMINISTERED (341 patients)
OBESITY (341 patients)
DYSURIA (340 patients)
TOOTH EXTRACTION (338 patients)
AGITATION (338 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (335 patients)
INFLUENZA LIKE ILLNESS (333 patients)
OVERDOSE (328 patients)
WHEEZING (327 patients)
DYSARTHRIA (326 patients)
DYSPHONIA (326 patients)
FLATULENCE (325 patients)
ACUTE MYOCARDIAL INFARCTION (325 patients)
HERPES ZOSTER (325 patients)
ANOREXIA (323 patients)
HAEMATOCRIT DECREASED (321 patients)
TOOTH DISORDER (320 patients)
BLOOD SODIUM DECREASED (314 patients)
DENTAL CARIES (313 patients)
LYMPHADENOPATHY (313 patients)
URINARY INCONTINENCE (313 patients)
HYPERKALAEMIA (311 patients)
DISORIENTATION (310 patients)
CARDIAC MURMUR (310 patients)

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Recent FactMed Activity for HYDROCHLOROTHIAZIDE

Issue	Description / Topic	Timestamp
QUESTION LYMPHOCYTOSIS	Ive been on a thiazide diuretic Bendroflumethazide for 13 years and have been diagnosed with CLL could the drug cause this?	2014-11-16 03:23:33
QUESTION HEAD INJURY	Should hydrochlorothiazide be given to a head injury patient already experiencing syncope?	2014-12-06 18:06:14
QUESTION ASTHENIA	In which decease AQUAZIDE-R IS used?	2015-03-08 05:01:05
QUESTION GOUT	I was recently diagnosed with gout. I took hydrochlorothiazide for 4 years and suspect this may have led to my developing gout. Having quit taking the HCTZ, I'm wondering if I'm still at risk for more gout attacks. Can quitting the HCTZ reverse the hyperurecemia?	2015-03-19 19:59:06
QUESTION RHEUMATOID FACTOR INCREASED	Hello!! My wife aged 52 has hypertension since one year , since last six month she was on HCTZ ,SINCE LAST TWO MONTHS SHE WAS COMPLAING about joint pain, her RA factor found very high, Any suggestions or information plz post here.	2015-04-24 06:20:27
QUESTION PARKINSONISM	Hi, my wife has last week been diagnosed with Parkinsonism. She has been using Micardis Plus for over 10 years for her high blood pressure. How sure are we about hydrochlorothiazide (present in Micardis) can cause Parkinsonism?	2015-06-06 08:58:23
QUESTION hair loss	69 years old. Sept 2014 dr put me on HCTZ (at this time I also saw another doctor) and both took my BP and listend to my heart. Jan. 2015 diagnosed with Moderate Aortic Stenosis plus my hair is thinned out - no hair growth. I am still on HCTZ for BP. Dr. wants to change to bystolic 5 mg. What is the best BP for Aortic Stenosis and stop hair loss?	2015-06-17 09:45:19
QUESTION FEMUR FRACTURE	Hey there..I ran into this post, and really felt the need to reply. I mylesf (you can read more about me by clicking my username..but I’m not too interesting!) have OI as well. I have type 3..and am indeed in a wheelchair. Strangely, I too had the option of the pins in the leg/arms..but never had it done. My mom wanted to wait for me to choose as well, and truthfully, I don’t think it would have done much. I’ll never walk, which is perfectly fine..so there isn’t much need for all the painful surgeries. None the less, I live a perfectly normal life..go to college..have friends, and all that. I’m 25, and I’d say quite healthy. I’ll also say I haven’t had a broken bone in years (though I had several throughout my childhood..from ribs..to arms..legs..etc). I was also born with a fractured skull and a broken leg. None the less..I’ve found that at about age 16 things really started to slow down with the breaking, and I have found that my bones have become far stronger. I can do things which I never could..including getting out of my chair, in it, etc. I can’t walk, but really..it doesn’t affect me in a negative way.Anyway..I rambled..I always do..haha! It was interesting to see someone else who has OI. I hope all is well..and perhaps we could talk some time.((sorry for the double post..I meant to post under my actual account..))Bye for now!-Joe	2015-07-13 07:08:31
QUESTION PEMPHIGUS	I have a ssbsrer case of pempygis from hydrochlorizide.. Dr gave me prednisone and clindamyacin.. it is helping. . Will I have this skin disease forever? Does It go away?	2015-10-01 09:00:28
QUESTION PEMPHIGUS	I also have pemphigus from hydrochlorothiazide...my dr. Prescribed me prednisone and clindomycin..it is helping...will I have this forever? Will it kill me?	2015-10-03 21:26:01
QUESTION GENITAL HERPES	Hello I have come to realize taking HCTZ (hydrochlorothiazide) causes Herpes outbreaks. I already had genital herpes but only had an outbreak once a year or every two years. Since I started taking HCTZ for high blood pressure, I have constant outbreaks! One isn't even healed up yet before I am getting another outbreak! I am going to my doctor to change medications. It does work well for my blood pressure even though it is a diuretic. I wanted to let everyone know. Anyone else found this to be true?	2015-10-13 12:53:27
QUESTION GROIN PAIN	Does hydrochlorothiazi effect potassium level?	2015-12-11 21:45:21
QUESTION CHOKING	I have been taking hydrochlorthiazide since middle of my 30 im 42 now and feels like im choking and i get swollen lymph node around neck blurry vision headaches low fever its awful	2015-12-26 23:57:01
QUESTION DRUG INTERACTION	Does taking of travatan and HYDROCHLOROTHIAZIDE cause a side effect of blood in the urine?	2015-12-28 17:09:40
QUESTION ALCOHOL WITHDRAWAL SYNDROME	I was recently diagnosed with high blood pressure & prescribed HYDROCHLOROTHIAZIDE. I was told lifestyle changes would also aide in lower my blood pressure so I stopped drinking & significantly cut back smoking. After about 2 weeks of taking the meds & not drinking, I've suddenly came down with severe headaches that at times can be unbearable. Is it possible for there to be any correlation of the 2 that could be bringing these headaches about? I plan to go see my PCP ASAP but thought I'd at least ask until I go.	2016-01-16 14:16:57
QUESTION BUNDLE BRANCH BLOCK RIGHT	i have been taking lisinopril with hctz 20mg for 4 years for the treatment of high blood pressure. Otherwise perfectly healthy and all labs are in normal ranges., I have recently been diagnosed with RBBB via an ecg. All labs are in normal range and I feel fine , play a full court game of basketball twice weekly. I hit the gym on the treadmill and exercise bike for cardio for 30 minutes each , every other day. I stopped taking the bp meds last week and went for an ecg yesterday and now ecg shows as 99 on the qrs complex. While taking the bp meds it was showing as 136 - 146 on the qrs complex. Does this make sense to anyone? thought and comments are welcome!!!	2016-01-20 10:02:28
QUESTION RENAL FAILURE	Is it common for "Hydrochlorothazide" 12.5 mg to effect the kidneys ?	2016-04-15 20:12:54
QUESTION ANTICHOLINERGIC SYNDROME	I've been taking hydrochlorthiazide for decades to reduce bloating and sinus pain. I am 64 now. Have I put myself at risk for dementia because of any anticholinergic effects the drug might have?	2016-04-23 21:05:54
QUESTION DRUG INTERACTION	Can I take dyazide with low dose aspirin?	2016-05-08 12:41:52
QUESTION LICHEN PLANUS	Can lichen plants be triggered or caused by hydrochlorathiazide	2016-08-05 21:54:21
QUESTION SCIATICA	I have been taking lisinopril hctz 10 12.5 for probably 5 yrs. I have several side effects, caugh, insomnia, cold symptoms. For the last 2 weeks I have been trying to ween myself off the med. I have also taken myself off simvastatin 20 mg. Now I have developed painful sciatica. Is there a connection with these drugs? I am 68.	2017-01-24 03:14:20
QUESTION SCIATICA	I have been taking lisinopril hctz 10 12.5 for probably 5 yrs. I have several side effects, caugh, insomnia, cold symptoms. For the last 2 weeks I have been trying to ween myself off the med. I have also taken myself off simvastatin 20 mg. Now I have developed painful sciatica. Is there a connection with these drugs? I am 68.	2017-01-24 08:21:24
QUESTION TENDONITIS	Afhdjhfdifj jfbdjw efwjjfwefkwenwj gbfhewifw gbuewhifjw weifhwef jvsnkqwkf jqwokd n jwegjwfoewjih fnejnfbvuef fijiwrotpojegi owkemwnjrj rowjrokwk nirjwok wn wjrkwkr bvncmcieughfijdf hiwjeow jw riwjoe wkkfn iw jrwjfeigeiwkjfehbks srhreiutregreshv hur erh weiiewhbahewvhjvetjhwahj vahwtvhwebrbw hbewhr rwhetiuawhhewahtbehtbwehjbfsdhlfuh hfwebfa	2017-02-22 08:00:19
QUESTION URETHRAL PAIN	Can hydrochlorothiazide cause urethra pain	2017-03-29 17:14:20
QUESTION MACULAR DEGENERATION	Can hydrochlorothiazide exacerbate macular degeneration-.	2017-04-03 22:08:52
QUESTION BLADDER PAIN	I TAKE 12.5 MG HYDROCHLOROTHIAZIDE BUT FOR MOST OF THE PAST 2 1/2 YEARS TOOK 25 MG DAILY. I'VE HAD RECURRING BLADDER PAIN SINCE I BEGAN TAKING IT. MY DR. WON'T LET ME STOP BECAUSE HE SAYS IT'S SUCH A LOW DOSE. I THINK I SHOULD STOP TAKING IT & HE SHOULD PRESCRIBE SOMETHING ELSE. WHAT DO YOU THINK? I JUST FOUND OUT THAT HYDROCHLOROTHIAZIDE CAN CAUSE BLADDER PAIN.	2017-05-22 12:22:07
QUESTION BLADDER PAIN	I TAKE 12.5 MG HYDROCHLOROTHIAZIDE BUT FOR MOST OF THE PAST 2 1/2 YEARS TOOK 25 MG DAILY. I'VE HAD RECURRING BLADDER PAIN SINCE I BEGAN TAKING IT. MY DR. WON'T LET ME STOP BECAUSE HE SAYS IT'S SUCH A LOW DOSE. I THINK I SHOULD STOP TAKING IT & HE SHOULD PRESCRIBE SOMETHING ELSE. WHAT DO YOU THINK? I JUST FOUND OUT THAT HYDROCHLOROTHIAZIDE CAN CAUSE BLADDER PAIN. I DIDN'T TAKE IT THIS MORNING AND THE PAIN IS LESS.	2017-05-23 13:43:11
QUESTION BLOOD GLUCOSE INCREASED	Hi, I took HCTZ since 2005, I stopped taking it in 2016, After stopping HCTZ I started having issues with hypoglycemia. I am diabetic and was on glipizide and metformin at the time. I complained to my dr for two months about the hypoglycemia before getting off the glipizide myself which stopped the low blood sugar issues. I also noticed that the neuropathy seemed to clear up some after stopping HCTZ. When I told my Dr the HCTZ had caused my blood sugars to go up he denied it. I still do not take it or glipizide and my sugars are more stable.	2017-07-13 12:20:15

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