About this FactMed analysis covering adverse side effect reports of KREMEZIN patients who developed REFLEXES ABNORMAL.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 2 individuals taking KREMEZIN reported REFLEXES ABNORMAL to the FDA. A total of 441 KREMEZIN drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between KREMEZIN and REFLEXES ABNORMAL. In doing so, we compare KREMEZIN with other drugs that cause REFLEXES ABNORMAL, to help you evaluate whether or not KREMEZIN causes REFLEXES ABNORMAL. Likewise, this page shows the most highly-reported side effects of KREMEZIN, so you can see if REFLEXES ABNORMAL ranks among KREMEZIN's most well-known side effects.
Summary Statistics
Reports of KREMEZIN causing REFLEXES ABNORMAL: 2
Reports of any side effect of KREMEZIN : 441
Percentage of KREMEZIN patients where REFLEXES ABNORMAL is a reported side effect: 0.4535%

FDA reports of any drug causing REFLEXES ABNORMAL : 276
Average percentage for all medicated patients where REFLEXES ABNORMAL is reported as a complication: 0.0017%

Physician opinion on KREMEZIN as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing KREMEZIN:
RENAL FAILURE CHRONIC ( 62 patients )
RENAL FAILURE ( 19 patients )
AZOTAEMIA ( 17 patients )
RENAL IMPAIRMENT ( 9 patients )
PROPHYLAXIS ( 8 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 8 patients )
HYPERTENSION ( 6 patients )
DIABETIC NEPHROPATHY ( 6 patients )
DRUG USE FOR UNKNOWN INDICATION ( 5 patients )
SPINAL OSTEOARTHRITIS ( 3 patients )
DETOXIFICATION ( 3 patients )
IRON OVERLOAD ( 3 patients )
DIABETES MELLITUS ( 2 patients )
GLOMERULONEPHRITIS CHRONIC ( 2 patients )
NEPHROSCLEROSIS ( 2 patients )
HYPERLIPIDAEMIA ( 2 patients )
BLOOD POTASSIUM INCREASED ( 1 patients )
GASTROOESOPHAGEAL REFLUX DISEASE ( 1 patients )
RENAL DISORDER ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with REFLEXES ABNORMAL:

AMITRIPTYLINE HYDROCHLORIDE (24 patients)
TRITTICO (20 patients)
TYSABRI (18 patients)
VIOXX (16 patients)
AVONEX (16 patients)
LANSOPRAZOLE (14 patients)
FOSAMAX (13 patients)
ZYPREXA (13 patients)
LORAZEPAM (13 patients)
ALENDRONATE SODIUM (11 patients)
CYMBALTA (11 patients)
METHOTREXATE (10 patients)
PAXIL (10 patients)
SIMVASTATIN (10 patients)
TRUXAL (10 patients)
LOSARTAN POTASSIUM (10 patients)
CYCLOSPORINE (10 patients)
DIAZEPAM (10 patients)
NEURONTIN (10 patients)
AMLODIPINE (9 patients)
ASPIRIN (9 patients)
CARBAMAZEPINE (9 patients)
LYRICA (9 patients)
GABAPENTIN (8 patients)
OMEPRAZOLE (8 patients)
METHYLPREDNISOLONE (8 patients)
CLOZARIL (8 patients)
HUMIRA (7 patients)
IMITREX (7 patients)
PALIPERIDONE (7 patients)
RISPERDAL (7 patients)
RISPERIDONE (7 patients)
FAMVIR (7 patients)
PREDNISONE TAB (6 patients)
VALPROIC ACID (6 patients)
TAMOXIFEN CITRATE (6 patients)
LEPONEX (6 patients)
LIPITOR (6 patients)
METRONIDAZOLE (6 patients)
RISEDRONATE SODIUM (6 patients)
INSULIN (6 patients)
LAMIVUDINE (6 patients)
LASIX (6 patients)
MIRTAZAPINE (6 patients)
NEORAL (6 patients)
LEVOTHYROXINE SODIUM (5 patients)
OXYCODONE HCL (5 patients)
PARLODEL (5 patients)
REBIF (5 patients)
ALLOPURINOL (5 patients)
AMANTADINE HCL (5 patients)
AMBIEN (5 patients)
VALPROATE SODIUM (5 patients)
BACLOFEN (5 patients)
NORVASC (5 patients)
CALCIUM CARBONATE (5 patients)
FLUOXETINE (5 patients)
SYNTHROID (5 patients)
FUROSEMIDE (5 patients)
TEGRETOL (5 patients)
HYDROCODONE (HYDROCODONE) (5 patients)
CIPROFLOXACIN (5 patients)
LAMICTAL (5 patients)
LISINOPRIL (5 patients)
METFORMIN HCL (5 patients)
DIGOXIN (4 patients)
FLUDARABINE PHOSPHATE (4 patients)
ACETAMINOPHEN (4 patients)
OTHER TYPE OF GASTROINTESTINAL PREPARATION () (4 patients)
VENLAFAXINE HCL (4 patients)
ZOLPIDEM TARTRATE (4 patients)
PREDNISONE (4 patients)
EFFEXOR (4 patients)
SENOKOT (4 patients)
ALPRAZOLAM (4 patients)
LEXAPRO (4 patients)
AMLODIPINE BESYLATE (4 patients)
AMOXICILLIN AND CLAVULANATE POTASSIUM (4 patients)
PLAVIX (4 patients)
ANTIDEPRESSANTS () (4 patients)
ANTIEPILEPTICS () (4 patients)
ANTIHISTAMINES FOR SYSTEMIC USE () (4 patients)
PROZAC (4 patients)
ANTIPSYCHOTICS () (4 patients)
TRAMADOL HCL (4 patients)
ZOLOFT (4 patients)
LACTULOSE (4 patients)
LANTUS (4 patients)
AZATHIOPRINE (4 patients)
METOPROLOL TARTRATE (4 patients)
BENZODIAZEPINE DERIVATIVES() (4 patients)
NEXIUM (4 patients)
ORAL ANTIDIABETICS () (4 patients)
OXYCONTIN (4 patients)
PROPRANOLOL (4 patients)
PREDNISOLONE (4 patients)
DOXORUBICIN HCL (4 patients)
DULCOLAX (4 patients)
CARBOPLATIN (4 patients)
ETOPOSIDE (4 patients)
PRISTIQ (4 patients)
TACROLIMUS (4 patients)
TEGRETOL-XR (4 patients)
FUCIDINE CAP (4 patients)
HALOPERIDOL (4 patients)
HUMALOG (4 patients)
HYDROMORPHONE HCL (4 patients)
WELLBUTRIN (4 patients)
CLONAZEPAM (4 patients)
METHADONE HYDROCHLORIDE (4 patients)
CYCLOPHOSPHAMIDE (4 patients)
DECONGESTANTS AND ANTIALLERGICS () (4 patients)
DIAMICRON (4 patients)
PRAVACHOL (3 patients)
ABACAVIR (3 patients)
MYCOPHENOLATE MOFETIL (3 patients)
PREVACID (3 patients)
PROCRIT /00928302/ (3 patients)
ACETYLSALICYLIC ACID SRT (3 patients)
METHYCOBAL (3 patients)
ADANCOR (3 patients)
MYSOLINE (3 patients)
ALFAROL (3 patients)
GLIBENCLAMIDE (3 patients)
ALTACE (3 patients)
LOXONIN (3 patients)
AMITRIPTYLINE HCL (3 patients)
NEXAVAR (3 patients)
ANTIDIABETICS (3 patients)
SYNTOCINON (3 patients)
FLUOXETINE HCL (3 patients)
SAQUINAVIR (3 patients)
HYDROCORTISONE (3 patients)
VICODIN (3 patients)
BACTRIM (3 patients)
OLANZAPINE (3 patients)
BLINDED CGS 20267 T30748+ (3 patients)
BLINDED NO TREATMENT RECEIVED NOMED (3 patients)
BLINDED PLACEBO PLACEBO (3 patients)
OROXINE (3 patients)
PAROXETINE HCL (3 patients)
PAXIL CR (3 patients)
PRAVASTATIN (3 patients)
DOXEPIN HCL (3 patients)
FLAGYL (3 patients)
FLEXERIL (3 patients)
SUSTIVA (3 patients)
THIOTEPA (3 patients)
HYDROCHLOROTHIAZIDE (3 patients)
CIPROFLOXACIN HCL (3 patients)
CITALOPRAM HYDROBROMIDE (3 patients)
VALTURNA (3 patients)
ZIDOVUDINE (3 patients)
XANAX (3 patients)
VITAMIN D (3 patients)
LEVOMEPROMAZINE (3 patients)
LIORESAL (3 patients)
COUMADIN (3 patients)
COZAAR (3 patients)
CYTARABINE (3 patients)
DEPAKENE (3 patients)
DEROXAT (3 patients)
DEXAMETHASONE TAB (3 patients)
MUCOSTA (3 patients)
METHERGINE (2 patients)
NUBAIN (2 patients)
NYSTATIN (2 patients)
ACTONEL (2 patients)
LOTENSIN (2 patients)
NITROGLYCERIN (2 patients)
ADVAIR DISKUS 100/50 (2 patients)
ORAMORPH SR (2 patients)
ZYVOX (2 patients)
METHYLERGOMETRINE MALEATE (2 patients)
AMOXICILLIN (2 patients)
OFLOXACIN (2 patients)
AMSACRINE (2 patients)
ANALGESIA (2 patients)
ANALGESIC() (2 patients)
PANTOPRAZOLE (2 patients)
ANPLAG (2 patients)
LIDOCAINE (2 patients)
LUPRON (2 patients)
MEGACE (2 patients)
METOCLOPRAMIDE (2 patients)
MIANSERIN (2 patients)
MORPHINE SULFATE (2 patients)
MOVIPREP (2 patients)
NAMENDA (2 patients)
BETAFERON (2 patients)
NITRIC OXIDE (2 patients)
NORTRIPTYLINE HCL (2 patients)
NORVIR (2 patients)
NOVOLOG (2 patients)
BISACODYL (2 patients)
BLOPRESS (2 patients)
PARACETAMOL (2 patients)
CALBLOCK (2 patients)
CALCIUM CITRATE (2 patients)
COLACE (2 patients)
LODALES (2 patients)
COPAXONE (2 patients)
LORTAB (2 patients)
MAVIK (2 patients)
MELOXICAM (2 patients)
MELPHALAN (2 patients)
CRESTOR (2 patients)
DECADRON (2 patients)
MORPHINE (2 patients)
MOTRIN (2 patients)
Most common side effects for patients taking KREMEZIN:
BLOOD CREATININE INCREASED (69 patients)
RENAL IMPAIRMENT (51 patients)
BLOOD UREA INCREASED (44 patients)
RENAL FAILURE CHRONIC (37 patients)
RENAL FAILURE (32 patients)
HYPERKALAEMIA (27 patients)
RENAL FAILURE ACUTE (26 patients)
CARDIAC FAILURE (26 patients)
RHABDOMYOLYSIS (25 patients)
ANAEMIA (21 patients)
NAUSEA (21 patients)
PYREXIA (19 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (17 patients)
URINARY TRACT INFECTION (16 patients)
EOSINOPHIL COUNT INCREASED (16 patients)
HYPERURICAEMIA (16 patients)
OEDEMA (15 patients)
HYPERGLYCAEMIA (15 patients)
CARDIAC FAILURE CONGESTIVE (14 patients)
CEREBRAL HAEMORRHAGE (14 patients)
DIARRHOEA (14 patients)
HYPERTENSION (14 patients)
INTERSTITIAL LUNG DISEASE (13 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (13 patients)
ASTHENIA (13 patients)
C-REACTIVE PROTEIN INCREASED (13 patients)
CEREBRAL INFARCTION (13 patients)
PNEUMONIA (13 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (13 patients)
HAEMODIALYSIS (13 patients)
PLATELET COUNT DECREASED (13 patients)
DECREASED APPETITE (12 patients)
HAEMOGLOBIN DECREASED (12 patients)
VOMITING (12 patients)
MALAISE (11 patients)
BLOOD PRESSURE DECREASED (11 patients)
BLOOD PRESSURE INCREASED (11 patients)
DIALYSIS (11 patients)
GAIT DISTURBANCE (11 patients)
CONDITION AGGRAVATED (10 patients)
THROMBOCYTOPENIA (10 patients)
MYALGIA (9 patients)
ALANINE AMINOTRANSFERASE INCREASED (9 patients)
ALTERED STATE OF CONSCIOUSNESS (9 patients)
DEHYDRATION (9 patients)
DRUG INTERACTION (9 patients)
MYOGLOBINURIA (9 patients)
HYPOGLYCAEMIA (9 patients)
BLOOD CREATINE INCREASED (8 patients)
PULMONARY OEDEMA (8 patients)
BLOOD POTASSIUM DECREASED (8 patients)
BLOOD POTASSIUM INCREASED (8 patients)
PLEURAL EFFUSION (8 patients)
DYSKINESIA (8 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (8 patients)
MYOCLONUS (8 patients)
TRANSIENT ISCHAEMIC ATTACK (8 patients)
WHITE BLOOD CELL COUNT DECREASED (8 patients)
PROSTATE CANCER (8 patients)
ANGINA PECTORIS (7 patients)
ANOREXIA (7 patients)
PYELONEPHRITIS (7 patients)
ATRIAL FLUTTER (7 patients)
MYOCARDIAL INFARCTION (7 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (7 patients)
CARDIAC FAILURE CHRONIC (7 patients)
NEPHROGENIC ANAEMIA (7 patients)
CONVULSION (7 patients)
DIABETIC NEPHROPATHY (7 patients)
RENAL DISORDER (7 patients)
ECZEMA (7 patients)
STEVENS-JOHNSON SYNDROME (7 patients)
GASTRIC ULCER HAEMORRHAGE (7 patients)
GASTROINTESTINAL HAEMORRHAGE (7 patients)
HEPATIC FUNCTION ABNORMAL (7 patients)
PNEUMONIA ASPIRATION (7 patients)
ASCITES (6 patients)
VENTRICULAR FIBRILLATION (6 patients)
BLOOD BILIRUBIN INCREASED (6 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (6 patients)
CARDIAC ARREST (6 patients)
COLOUR BLINDNESS (6 patients)
PERITONITIS (6 patients)
RASH (6 patients)
LIVER DISORDER (6 patients)
TOXIC EPIDERMAL NECROLYSIS (6 patients)
WEIGHT INCREASED (6 patients)
RESPIRATORY FAILURE (5 patients)
OVERDOSE (5 patients)
BEDRIDDEN (5 patients)
OESOPHAGEAL ULCER (5 patients)
RECTAL PERFORATION (5 patients)
RESPIRATORY ARREST (5 patients)
DEATH (5 patients)
RED BLOOD CELL COUNT DECREASED (5 patients)
DYSARTHRIA (5 patients)
LIPASE INCREASED (5 patients)
SHOCK (5 patients)
LOSS OF CONSCIOUSNESS (5 patients)
SPEECH DISORDER (5 patients)
FALL (5 patients)
FATIGUE (5 patients)
MENTAL DISORDER (5 patients)
HYPERCALCAEMIA (5 patients)
HYPONATRAEMIA (5 patients)
PULMONARY CONGESTION (5 patients)
ABDOMINAL PAIN (4 patients)
AGITATION (4 patients)
NEPHROSCLEROSIS (4 patients)
BLOOD GLUCOSE INCREASED (4 patients)
LARGE INTESTINAL OBSTRUCTION (4 patients)
BRADYCARDIA (4 patients)
LYMPHOPENIA (4 patients)
MELAENA (4 patients)
CARDIO-RESPIRATORY ARREST (4 patients)
CHEST PAIN (4 patients)
NEUTROPHIL COUNT DECREASED (4 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (4 patients)
DIABETIC KETOACIDOSIS (4 patients)
DIABETIC NEUROPATHY (4 patients)
DIASTOLIC DYSFUNCTION (4 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (4 patients)
DRUG ERUPTION (4 patients)
LUNG INFILTRATION (4 patients)
FEBRILE NEUTROPENIA (4 patients)
FEMUR FRACTURE (4 patients)
GRANULOCYTOPENIA (4 patients)
URINARY RETENTION (4 patients)
HAEMORRHAGIC DIATHESIS (4 patients)
HYPERPHOSPHATASAEMIA (4 patients)
HYPOCALCAEMIA (4 patients)
PO2 ABNORMAL (4 patients)
ABASIA (3 patients)
ABDOMINAL DISTENSION (3 patients)
ABNORMAL BEHAVIOUR (3 patients)
ACUTE RESPIRATORY DISTRESS SYNDROME (3 patients)
AGRANULOCYTOSIS (3 patients)
ANAEMIA MACROCYTIC (3 patients)
ANAPHYLACTIC SHOCK (3 patients)
ANTI-INSULIN ANTIBODY INCREASED (3 patients)
PROTEINURIA (3 patients)
ASTERIXIS (3 patients)
BENIGN PROSTATIC HYPERPLASIA (3 patients)
URINARY INCONTINENCE (3 patients)
BLOOD ALBUMIN DECREASED (3 patients)
BLOOD CHOLESTEROL INCREASED (3 patients)
BLOOD PRESSURE SYSTOLIC INCREASED (3 patients)
LOGORRHOEA (3 patients)
SUDDEN CARDIAC DEATH (3 patients)
CARDIAC FAILURE ACUTE (3 patients)
CARDIOVASCULAR DISORDER (3 patients)
MYOCARDIAL ISCHAEMIA (3 patients)
TREMOR (3 patients)
CHOLELITHIASIS (3 patients)
COMMUNICATION DISORDER (3 patients)
CONFUSIONAL STATE (3 patients)
CONSTIPATION (3 patients)
DERMATITIS EXFOLIATIVE (3 patients)
DYSPNOEA (3 patients)
RESTLESSNESS (3 patients)
ENCEPHALOPATHY (3 patients)
EOSINOPHILIA (3 patients)
RHINITIS ALLERGIC (3 patients)
SEROTONIN SYNDROME (3 patients)
EYELID OEDEMA (3 patients)
FAECAL INCONTINENCE (3 patients)
FEELING ABNORMAL (3 patients)
MANIA (3 patients)
FLUID RETENTION (3 patients)
TOOTHACHE (3 patients)
GASTRITIS (3 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (3 patients)
TOXIC SKIN ERUPTION (3 patients)
GLUCOSE TOLERANCE IMPAIRED (3 patients)
TUBULOINTERSTITIAL NEPHRITIS (3 patients)
HAEMATOCRIT DECREASED (3 patients)
HAEMATURIA (3 patients)
URINE OUTPUT DECREASED (3 patients)
VASCULITIS (3 patients)
HICCUPS (3 patients)
OEDEMA PERIPHERAL (3 patients)
HYPERBILIRUBINAEMIA (3 patients)
HYPOAESTHESIA (3 patients)
INFECTION (3 patients)
INSOMNIA (3 patients)
PULMONARY HAEMORRHAGE (3 patients)
OSTEONECROSIS OF JAW (2 patients)
ACIDOSIS (2 patients)
AKATHISIA (2 patients)
ANTI-INSULIN ANTIBODY POSITIVE (2 patients)
ANXIETY (2 patients)
APLASIA PURE RED CELL (2 patients)
RASH GENERALISED (2 patients)
BLOOD CREATINE PHOSPHOKINASE MB (2 patients)
BLOOD PRESSURE DIASTOLIC DECREASED (2 patients)
BLOOD PRESSURE FLUCTUATION (2 patients)
BLOOD PRESSURE INADEQUATELY CONTROLLED (2 patients)
DEPRESSED MOOD (2 patients)
PRURITUS (2 patients)
DIABETES MELLITUS INADEQUATE CONTROL (2 patients)
DISEASE PROGRESSION (2 patients)
DIZZINESS (2 patients)
DRUG DOSE OMISSION (2 patients)
ELECTROCARDIOGRAM QT PROLONGED (2 patients)
HYPOCHLORAEMIA (2 patients)
HYPOKALAEMIA (2 patients)
HYPOPHAGIA (2 patients)
HYPOPHOSPHATAEMIA (2 patients)
HYPOTHYROIDISM (2 patients)
HYPOTONIA (2 patients)

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