Is SICK SINUS SYNDROME a side effect of LEVOTHYROXINE SODIUM ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of LEVOTHYROXINE SODIUM patients who developed SICK SINUS SYNDROME.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 37 individuals taking LEVOTHYROXINE SODIUM reported SICK SINUS SYNDROME to the FDA. A total of 52076 LEVOTHYROXINE SODIUM drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between LEVOTHYROXINE SODIUM and SICK SINUS SYNDROME. In doing so, we compare LEVOTHYROXINE SODIUM with other drugs that cause SICK SINUS SYNDROME, to help you evaluate whether or not LEVOTHYROXINE SODIUM causes SICK SINUS SYNDROME. Likewise, this page shows the most highly-reported side effects of LEVOTHYROXINE SODIUM, so you can see if SICK SINUS SYNDROME ranks among LEVOTHYROXINE SODIUM's most well-known side effects.

Summary Statistics
Reports of LEVOTHYROXINE SODIUM causing SICK SINUS SYNDROME: 37
Reports of any side effect of LEVOTHYROXINE SODIUM : 52076
Percentage of LEVOTHYROXINE SODIUM patients where SICK SINUS SYNDROME is a reported side effect: 0.0711%

FDA reports of any drug causing SICK SINUS SYNDROME : 1709
Average percentage for all medicated patients where SICK SINUS SYNDROME is reported as a complication: 0.0107%

Physician opinion on LEVOTHYROXINE SODIUM as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing LEVOTHYROXINE SODIUM:

HYPOTHYROIDISM ( 9288 patients )
DRUG USE FOR UNKNOWN INDICATION ( 2983 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 2373 patients )
THYROID DISORDER ( 2258 patients )
THYROIDECTOMY ( 377 patients )
AUTOIMMUNE THYROIDITIS ( 301 patients )
HYPERTHYROIDISM ( 281 patients )
BLOOD THYROID STIMULATING HORMONE DECREASED ( 115 patients )
HYPOPITUITARISM ( 115 patients )
GOITRE ( 114 patients )
THYROID HORMONE REPLACEMENT THERAPY ( 82 patients )
HORMONE REPLACEMENT THERAPY ( 78 patients )
ILL-DEFINED DISORDER ( 77 patients )
PRIMARY HYPOTHYROIDISM ( 75 patients )
BASEDOW'S DISEASE ( 74 patients )
THYROID CANCER ( 69 patients )
THYROIDITIS ( 55 patients )
THYROID FUNCTION TEST ABNORMAL ( 51 patients )
THYROID THERAPY ( 48 patients )
POST PROCEDURAL HYPOTHYROIDISM ( 47 patients )
SECONDARY HYPOTHYROIDISM ( 37 patients )
THYROID OPERATION ( 28 patients )
DRUG EXPOSURE DURING PREGNANCY ( 25 patients )
THYROID NEOPLASM ( 23 patients )
THYROXINE THERAPY ( 21 patients )
THYROIDITIS CHRONIC ( 21 patients )
CONGENITAL HYPOTHYROIDISM ( 19 patients )
BLOOD THYROID STIMULATING HORMONE INCREASED ( 19 patients )
MYXOEDEMA ( 18 patients )
THYROXINE DECREASED ( 17 patients )
PROPHYLAXIS ( 16 patients )
FOETAL EXPOSURE DURING PREGNANCY ( 15 patients )
SUICIDE ATTEMPT ( 11 patients )
DEPRESSION ( 11 patients )
HYPERTENSION ( 11 patients )
SUPPLEMENTATION THERAPY ( 11 patients )
DIABETES MELLITUS ( 11 patients )
UNEVALUABLE EVENT ( 10 patients )
WEIGHT DECREASED ( 10 patients )
ACCIDENTAL DRUG INTAKE BY CHILD ( 9 patients )
MAJOR DEPRESSION ( 8 patients )
BLOOD THYROID STIMULATING HORMONE ABNORMAL ( 8 patients )
METABOLIC DISORDER ( 8 patients )
THYROID CYST ( 7 patients )
WEIGHT CONTROL ( 7 patients )
RADIOACTIVE IODINE THERAPY ( 7 patients )
BLOOD CHOLESTEROL INCREASED ( 6 patients )
CARDIOVASCULAR DISORDER ( 6 patients )
POSTPARTUM HYPOPITUITARISM ( 6 patients )
HYPOPARATHYROIDISM ( 6 patients )
ENDOCRINE DISORDER ( 6 patients )
HORMONE THERAPY ( 5 patients )
HYPOTENSION ( 4 patients )
SURGERY ( 4 patients )
RHEUMATOID ARTHRITIS ( 4 patients )
MATERNAL EXPOSURE DURING PREGNANCY ( 4 patients )
NEOPLASM ( 4 patients )
FOETAL EXPOSURE TIMING UNSPECIFIED ( 4 patients )
BIPOLAR DISORDER ( 3 patients )
HORMONE SUPPRESSION THERAPY ( 3 patients )
THYROID PAIN ( 3 patients )
THYROID DYSFUNCTION IN PREGNANCY ( 3 patients )
ANOREXIA NERVOSA ( 3 patients )
DRUG EXPOSURE VIA BREAST MILK ( 3 patients )
THYROXINE FREE DECREASED ( 3 patients )
TRI-IODOTHYRONINE DECREASED ( 3 patients )
INTENTIONAL OVERDOSE ( 3 patients )
PITUITARY TUMOUR BENIGN ( 3 patients )
EUTHYROID SICK SYNDROME ( 3 patients )
RETROPERITONEAL FIBROSIS ( 3 patients )
THYROIDECTOMY PARTIAL ( 3 patients )
BLOOD PRESSURE ( 3 patients )
DRUG ABUSE ( 3 patients )
BLOOD THYROID STIMULATING HORMONE ( 2 patients )
GENERAL PHYSICAL CONDITION ( 2 patients )
MATERNAL DRUGS AFFECTING FOETUS ( 2 patients )
PAIN ( 2 patients )
MATERNAL EXPOSURE TIMING UNSPECIFIED ( 2 patients )
THYROID HAEMORRHAGE ( 2 patients )
BLOOD TRIGLYCERIDES INCREASED ( 2 patients )
THYROID MASS ( 2 patients )
BREAST CANCER ( 2 patients )
ACUTE LYMPHOCYTIC LEUKAEMIA ( 2 patients )
PITUITARY TUMOUR ( 2 patients )
CARDIAC FAILURE ( 2 patients )
THYROID ADENOMA ( 2 patients )
NEOPLASM MALIGNANT ( 2 patients )
BLOOD PRESSURE INADEQUATELY CONTROLLED ( 2 patients )
OPEN WOUND ( 2 patients )
SCINTIGRAPHY ( 2 patients )
CONSTIPATION ( 2 patients )
GENERALISED RESISTANCE TO THYROID HORMONE ( 2 patients )
HYPOTHALAMO-PITUITARY DISORDER ( 2 patients )
PSYCHOTIC DISORDER ( 2 patients )
TOXIC NODULAR GOITRE ( 2 patients )
DEMENTIA ( 2 patients )
ELECTROLYTE SUBSTITUTION THERAPY ( 2 patients )
CARDIAC DISORDER ( 2 patients )
THERAPEUTIC PROCEDURE ( 2 patients )
DISEASE COMPLICATION ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
POST PROCEDURAL COMPLICATION ( 2 patients )
LOCAL SWELLING ( 2 patients )
POSTOPERATIVE CARE ( 2 patients )
NODULE ( 2 patients )
CHEST PAIN ( 2 patients )
HYPOPHYSECTOMY ( 1 patients )
OFF LABEL USE ( 1 patients )
SCHIZOPHRENIA ( 1 patients )
THYROXINE ( 1 patients )
ANXIETY ( 1 patients )
THYROID GLAND CANCER ( 1 patients )
DRUG RESISTANCE ( 1 patients )
ASCITES ( 1 patients )
CROHN'S DISEASE ( 1 patients )
PSEUDOHYPOPARATHYROIDISM ( 1 patients )
DRY SKIN ( 1 patients )
PARATHYROID DISORDER ( 1 patients )
SLEEP DISORDER ( 1 patients )
DELIRIUM ( 1 patients )
HORMONE LEVEL ABNORMAL ( 1 patients )
METABOLIC SYNDROME ( 1 patients )
QUADRIPARESIS ( 1 patients )
ACCIDENTAL EXPOSURE ( 1 patients )
ECONOMIC PROBLEM ( 1 patients )
PEPTIC ULCER ( 1 patients )
TREMOR ( 1 patients )
MIGRAINE ( 1 patients )
RADIOTHERAPY ( 1 patients )
THYROID NODULE REMOVAL ( 1 patients )
CALCIUM DEFICIENCY ( 1 patients )
EMBOLISM ARTERIAL ( 1 patients )
INFLAMMATION ( 1 patients )
TYPE 1 DIABETES MELLITUS ( 1 patients )
DIARRHOEA ( 1 patients )
HYPERLIPIDAEMIA ( 1 patients )
MYOCARDIAL INFARCTION ( 1 patients )
RAYNAUD'S PHENOMENON ( 1 patients )
ADRENAL INSUFFICIENCY ( 1 patients )
EPILEPSY ( 1 patients )
IRON DEFICIENCY ( 1 patients )
POLYCYSTIC OVARIES ( 1 patients )
BLOOD DISORDER ( 1 patients )
DISEASE RECURRENCE ( 1 patients )
NECK MASS ( 1 patients )
RENAL IMPAIRMENT ( 1 patients )
ALOPECIA ( 1 patients )
FATIGUE ( 1 patients )
JUVENILE ARTHRITIS ( 1 patients )
BLOOD PARATHYROID HORMONE INCREASED ( 1 patients )
DIZZINESS ( 1 patients )
HYPERTONIA ( 1 patients )
ANKYLOSING SPONDYLITIS ( 1 patients )
CHEMOTHERAPY ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
WRONG DRUG ADMINISTERED ( 1 patients )
DRUG DISPENSING ERROR ( 1 patients )
OEDEMA PERIPHERAL ( 1 patients )
ROUTINE HEALTH MAINTENANCE ( 1 patients )
COMPLETED SUICIDE ( 1 patients )
GASTROINTESTINAL HYPOMOTILITY ( 1 patients )
THYROID FUNCTION TEST NORMAL ( 1 patients )
THYROXINE ABNORMAL ( 1 patients )
ARTHRITIS ( 1 patients )
PROSTATE CANCER ( 1 patients )
THYROID GLAND SCAN ABNORMAL ( 1 patients )
PAPILLARY THYROID CANCER ( 1 patients )
SELF INJURIOUS BEHAVIOUR ( 1 patients )
ASTHMA ( 1 patients )
DECREASED ACTIVITY ( 1 patients )
HIV INFECTION ( 1 patients )
BRADYCARDIA ( 1 patients )
DYSPEPSIA ( 1 patients )
HYPOTHYROIDISM POSTOPERATIVE ( 1 patients )
PARATHYROIDECTOMY ( 1 patients )
SPINAL FRACTURE ( 1 patients )
METASTATIC RENAL CELL CARCINOMA ( 1 patients )
ACCIDENTAL OVERDOSE ( 1 patients )
BURN OF INTERNAL ORGANS ( 1 patients )
IMMUNOSUPPRESSION ( 1 patients )
PHARYNGEAL NEOPLASM ( 1 patients )
BIPOLAR II DISORDER ( 1 patients )
MUCOSAL DRYNESS ( 1 patients )
RASH ( 1 patients )
ADRENAL DISORDER ( 1 patients )
TYPE 2 DIABETES MELLITUS ( 1 patients )
BLOOD CORTICOTROPHIN DECREASED ( 1 patients )
HYPERPARATHYROIDISM ( 1 patients )
ADRENOCORTICAL INSUFFICIENCY CHRONIC ( 1 patients )
CARDIO-RESPIRATORY ARREST ( 1 patients )
IUCD COMPLICATION ( 1 patients )
WEIGHT ( 1 patients )
BLOOD PARATHYROID HORMONE DECREASED ( 1 patients )
DIURETIC THERAPY ( 1 patients )
ANGIOEDEMA ( 1 patients )
CEREBRAL CYST EXCISION ( 1 patients )
FIBROMYALGIA ( 1 patients )
HYPOMETABOLISM ( 1 patients )
RHINITIS ALLERGIC ( 1 patients )
THYROIDITIS ACUTE ( 1 patients )
ANOREXIA ( 1 patients )
LYME DISEASE ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with SICK SINUS SYNDROME:

ASPIRIN (419 patients)
VIOXX (361 patients)
DIGOXIN (327 patients)
FOSAMAX (257 patients)
COUMADIN (212 patients)
LASIX (185 patients)
PLAVIX (152 patients)
LIPITOR (147 patients)
FUROSEMIDE (140 patients)
SEROQUEL (124 patients)
LISINOPRIL (123 patients)
AVANDIA (115 patients)
ATENOLOL (114 patients)
ZOCOR (104 patients)
NORVASC (103 patients)
TOPROL-XL (102 patients)
WARFARIN SODIUM (100 patients)
POTASSIUM CHLORIDE (98 patients)
ZOMETA (94 patients)
SYNTHROID (91 patients)
SIMVASTATIN (81 patients)
ARICEPT (81 patients)
AMBIEN (78 patients)
PRILOSEC (77 patients)
PREVACID (76 patients)
ALBUTEROL (76 patients)
CELEBREX (75 patients)
LEVAQUIN (73 patients)
ALLOPURINOL (72 patients)
FLOMAX (72 patients)
FOLIC ACID (71 patients)
DIOVAN (69 patients)
METOPROLOL TARTRATE (68 patients)
PROTONIX (68 patients)
AREDIA (66 patients)
HYDROCHLOROTHIAZIDE (65 patients)
NEURONTIN (63 patients)
SPIRONOLACTONE (63 patients)
CARDIZEM (63 patients)
LANOXIN (62 patients)
NITROGLYCERIN (62 patients)
NEXIUM (62 patients)
ADVAIR DISKUS 100/50 (60 patients)
COREG (59 patients)
METFORMIN HCL (58 patients)
HEPARIN SODIUM INJECTION (58 patients)
REVLIMID (57 patients)
TEGRETOL (56 patients)
PERCOCET (55 patients)
XANAX (55 patients)
AMLODIPINE (54 patients)
CORDARONE (53 patients)
AMOXICILLIN (53 patients)
COLACE (52 patients)
ALPRAZOLAM (52 patients)
MAGNESIUM OXIDE (51 patients)
ZESTRIL (50 patients)
LORAZEPAM (50 patients)
DEXAMETHASONE (50 patients)
CRESTOR (49 patients)
MICARDIS (48 patients)
[THERAPY UNSPECIFIED] (48 patients)
OMEPRAZOLE (48 patients)
AMIODARONE HCL (48 patients)
THALOMID (48 patients)
VICODIN (47 patients)
METOPROLOL (47 patients)
CARVEDILOL (46 patients)
COZAAR (45 patients)
PREDNISONE (45 patients)
KLOR-CON (44 patients)
FENTANYL (43 patients)
MULTI-VITAMIN (43 patients)
BACTRIM (43 patients)
INSULIN (43 patients)
LOPRESSOR (42 patients)
LOVENOX (42 patients)
LOTREL (42 patients)
ZETIA (41 patients)
GLUCOPHAGE (41 patients)
ALDACTONE (41 patients)
CEPHALEXIN (41 patients)
ZOLOFT (40 patients)
KALETRA (40 patients)
PAXIL (40 patients)
MORPHINE (40 patients)
ACETAMINOPHEN (39 patients)
ACTOS (39 patients)
MULTI-VITAMINS (39 patients)
ACIPHEX (38 patients)
AMARYL (38 patients)
GLYBURIDE (37 patients)
LEVOTHYROXINE SODIUM (37 patients)
ZOFRAN (37 patients)
VITAMIN D (36 patients)
LINCOCIN (36 patients)
RISPERDAL (36 patients)
ALENDRONATE SODIUM (35 patients)
ALLEGRA (35 patients)
KEFLEX (35 patients)
HUMALOG (35 patients)
HUMALOG MIX 75/25 (34 patients)
PREDNISOLONE (34 patients)
SU-011,248 (34 patients)
IBUPROFEN (34 patients)
METOPROLOL SUCCINATE (33 patients)
PEN-VEE K (33 patients)
METFORMIN (33 patients)
ENALAPRIL MALEATE (33 patients)
METRONIDAZOLE (33 patients)
RAMIPRIL (33 patients)
ISOSORBIDE DINITRATE (33 patients)
SINGULAIR (32 patients)
CLINDAMYCIN (32 patients)
FORTEO (31 patients)
DILTIAZEM HYDROCHLORIDE (31 patients)
VERAPAMIL (31 patients)
POTASSIUM (31 patients)
PROPAFENONE HCL (31 patients)
DILTIAZEM (30 patients)
PEPCID (30 patients)
ATACAND (30 patients)
WARFARIN (30 patients)
TYLENOL-500 (30 patients)
ASCORBIC ACID (29 patients)
FAMOTIDINE (29 patients)
LANSOPRAZOLE (29 patients)
FOSAMAX PLUS D (28 patients)
PRINIVIL (28 patients)
LORTAB (28 patients)
GABAPENTIN (28 patients)
LANTUS (28 patients)
VYTORIN (28 patients)
AVANDAMET (27 patients)
THALIDOMIDE (27 patients)
PREMARIN (27 patients)
DECADRON (27 patients)
RANITIDINE (27 patients)
ANTIBIOTICS (27 patients)
PROMETHAZINE (26 patients)
EFAVIRENZ (26 patients)
LYRICA (26 patients)
MUCOSTA (26 patients)
CALCIUM (26 patients)
CARDURA (26 patients)
RADIATION THERAPY (25 patients)
VITAMIN E (25 patients)
CLONIDINE (25 patients)
ATROVENT (25 patients)
CYMBALTA (25 patients)
DIURETICS (25 patients)
TRICOR (25 patients)
OXYCODONE HCL AND ACETAMINOPHEN (24 patients)
ZYRTEC (24 patients)
DILTIAZEM HCL (24 patients)
ALTACE (24 patients)
METHOTREXATE (24 patients)
ULTRACET (24 patients)
ZITHROMAX (24 patients)
UROXATRAL (23 patients)
GLIPIZIDE (23 patients)
ZANTAC (23 patients)
PREDNISONE TAB (23 patients)
EXELON (23 patients)
HEPARIN (23 patients)
SPIRIVA (23 patients)
OXYCONTIN (23 patients)
VASOTEC (23 patients)
PAMIDRONATE DISODIUM (22 patients)
MECLIZINE (22 patients)
AXID (22 patients)
OXYGEN (22 patients)
TENORMIN (22 patients)
NIFEDIPINE (22 patients)
ERYTHROMYCIN (22 patients)
AVODART (22 patients)
SULFAMETHOXAZOLE (21 patients)
LEVOXYL (21 patients)
AVAPRO (21 patients)
LENADEX (21 patients)
ISOSORBIDE MONONITRATE (21 patients)
CYANOCOBALAMIN (21 patients)
MIRALAX (21 patients)
GLYCOLAX (20 patients)
PROVERA (20 patients)
BISOPROLOL (20 patients)
LAMIVUDINE (20 patients)
VELCADE (20 patients)
IRON (20 patients)
TORSEMIDE (20 patients)
MEGESTROL ACETATE (20 patients)
BLOPRESS (19 patients)
HYZAAR (19 patients)
PENICILLIN VK (19 patients)
BUMETANIDE (19 patients)
AMIODARONE (19 patients)
VIAGRA (19 patients)
IMDUR (19 patients)
CALCIUM (UNSPECIFIED) (19 patients)
NASONEX (19 patients)
BENZONATATE (19 patients)
SANDOSTATIN LAR (19 patients)
LACTULOSE (18 patients)
NAMENDA (18 patients)
K-DUR (18 patients)
BISOPROLOL FUMARATE (18 patients)
PERI-COLACE (18 patients)
DOXORUBICIN HCL (18 patients)
VISTARIL (18 patients)
ROCEPHIN (18 patients)

Most common side effects for patients taking LEVOTHYROXINE SODIUM:

NAUSEA (3280 patients)
DYSPNOEA (2973 patients)
FATIGUE (2923 patients)
PAIN (2527 patients)
DIZZINESS (2438 patients)
DIARRHOEA (2367 patients)
HEADACHE (2313 patients)
ASTHENIA (2249 patients)
VOMITING (2167 patients)
FALL (2092 patients)
DRUG INEFFECTIVE (2002 patients)
OEDEMA PERIPHERAL (1811 patients)
PYREXIA (1724 patients)
MALAISE (1697 patients)
DRUG INTERACTION (1683 patients)
ANXIETY (1681 patients)
ARTHRALGIA (1677 patients)
ANAEMIA (1596 patients)
PAIN IN EXTREMITY (1587 patients)
DEPRESSION (1563 patients)
PNEUMONIA (1517 patients)
WEIGHT DECREASED (1480 patients)
CHEST PAIN (1407 patients)
RENAL FAILURE ACUTE (1399 patients)
HYPOTENSION (1338 patients)
PRURITUS (1302 patients)
HYPERTENSION (1301 patients)
RASH (1296 patients)
ABDOMINAL PAIN (1257 patients)
CONFUSIONAL STATE (1236 patients)
DEHYDRATION (1228 patients)
BACK PAIN (1202 patients)
COUGH (1177 patients)
INSOMNIA (1175 patients)
WEIGHT INCREASED (1087 patients)
RENAL FAILURE (1076 patients)
URINARY TRACT INFECTION (1073 patients)
SOMNOLENCE (1047 patients)
CONSTIPATION (1047 patients)
HYPOTHYROIDISM (1013 patients)
ATRIAL FIBRILLATION (988 patients)
FEELING ABNORMAL (971 patients)
CONDITION AGGRAVATED (961 patients)
MYALGIA (958 patients)
TREMOR (935 patients)
HAEMOGLOBIN DECREASED (889 patients)
LOSS OF CONSCIOUSNESS (884 patients)
MUSCLE SPASMS (879 patients)
SYNCOPE (853 patients)
MYOCARDIAL INFARCTION (850 patients)
BLOOD GLUCOSE INCREASED (848 patients)
GAIT DISTURBANCE (846 patients)
DEATH (843 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (837 patients)
BLOOD PRESSURE INCREASED (831 patients)
PARAESTHESIA (821 patients)
CEREBROVASCULAR ACCIDENT (806 patients)
PULMONARY EMBOLISM (796 patients)
DECREASED APPETITE (795 patients)
ERYTHEMA (792 patients)
CONVULSION (785 patients)
ABDOMINAL PAIN UPPER (776 patients)
PALPITATIONS (776 patients)
HYPONATRAEMIA (754 patients)
FLUSHING (749 patients)
MUSCULAR WEAKNESS (748 patients)
HYPERHIDROSIS (740 patients)
THROMBOCYTOPENIA (717 patients)
CARDIAC FAILURE CONGESTIVE (717 patients)
DYSPHAGIA (709 patients)
ALOPECIA (690 patients)
PLEURAL EFFUSION (679 patients)
HYPOAESTHESIA (675 patients)
ALANINE AMINOTRANSFERASE INCREASED (665 patients)
BLOOD CREATININE INCREASED (654 patients)
VISION BLURRED (624 patients)
INJURY (619 patients)
DEEP VEIN THROMBOSIS (610 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (606 patients)
SEPSIS (599 patients)
TACHYCARDIA (597 patients)
CARDIAC FAILURE (590 patients)
HYPERSENSITIVITY (572 patients)
JOINT SWELLING (559 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (557 patients)
CHILLS (548 patients)
HYPOKALAEMIA (532 patients)
OVERDOSE (524 patients)
RESPIRATORY FAILURE (520 patients)
BRONCHITIS (519 patients)
RHABDOMYOLYSIS (519 patients)
BRADYCARDIA (516 patients)
INJECTION SITE PAIN (513 patients)
NEUTROPENIA (505 patients)
CONTUSION (502 patients)
CHEST DISCOMFORT (496 patients)
GASTROINTESTINAL HAEMORRHAGE (490 patients)
OSTEOARTHRITIS (479 patients)
MEMORY IMPAIRMENT (478 patients)
HEART RATE INCREASED (478 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (477 patients)
BALANCE DISORDER (473 patients)
INCORRECT DOSE ADMINISTERED (469 patients)
URTICARIA (469 patients)
CHOLELITHIASIS (466 patients)
WHITE BLOOD CELL COUNT DECREASED (460 patients)
AGITATION (460 patients)
PLATELET COUNT DECREASED (460 patients)
DYSPEPSIA (459 patients)
LETHARGY (454 patients)
DRY MOUTH (453 patients)
INFECTION (453 patients)
RENAL IMPAIRMENT (450 patients)
DIABETES MELLITUS (450 patients)
SINUSITIS (445 patients)
OEDEMA (441 patients)
AMNESIA (439 patients)
NASOPHARYNGITIS (427 patients)
HYPERKALAEMIA (424 patients)
EMOTIONAL DISTRESS (424 patients)
OROPHARYNGEAL PAIN (420 patients)
ABDOMINAL DISTENSION (414 patients)
HAEMORRHAGE (414 patients)
HYPOGLYCAEMIA (414 patients)
ABDOMINAL DISCOMFORT (412 patients)
SWELLING (411 patients)
RECTAL HAEMORRHAGE (410 patients)
CELLULITIS (409 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (406 patients)
BLOOD THYROID STIMULATING HORMONE INCREASED (402 patients)
SUICIDAL IDEATION (399 patients)
BLOOD PRESSURE DECREASED (397 patients)
ANOREXIA (394 patients)
BLOOD CHOLESTEROL INCREASED (386 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (379 patients)
ARTHRITIS (375 patients)
CARDIAC ARREST (374 patients)
CARDIAC DISORDER (373 patients)
INJECTION SITE ERYTHEMA (373 patients)
FEELING HOT (372 patients)
BONE PAIN (371 patients)
ASTHMA (370 patients)
MUSCULOSKELETAL PAIN (365 patients)
DRUG DOSE OMISSION (363 patients)
BURNING SENSATION (361 patients)
HEPATIC ENZYME INCREASED (357 patients)
RHEUMATOID ARTHRITIS (355 patients)
ARRHYTHMIA (353 patients)
NECK PAIN (353 patients)
LIVER FUNCTION TEST ABNORMAL (352 patients)
SPEECH DISORDER (351 patients)
DISORIENTATION (351 patients)
LEUKOPENIA (351 patients)
TRANSIENT ISCHAEMIC ATTACK (350 patients)
OFF LABEL USE (345 patients)
PANCYTOPENIA (344 patients)
VISUAL IMPAIRMENT (343 patients)
CORONARY ARTERY DISEASE (340 patients)
PANCREATITIS (334 patients)
PULMONARY OEDEMA (333 patients)
NEUROPATHY PERIPHERAL (331 patients)
SWELLING FACE (331 patients)
RENAL FAILURE CHRONIC (326 patients)
VERTIGO (326 patients)
MENTAL STATUS CHANGES (324 patients)
CYSTITIS (323 patients)
MULTI-ORGAN FAILURE (321 patients)
EPISTAXIS (320 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (320 patients)
SLEEP DISORDER (320 patients)
HAEMORRHOIDS (318 patients)
PHARMACEUTICAL PRODUCT COMPLAINT (315 patients)
INFLUENZA LIKE ILLNESS (311 patients)
INFLAMMATION (309 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (307 patients)
MUSCULOSKELETAL STIFFNESS (306 patients)
DRUG HYPERSENSITIVITY (303 patients)
ABASIA (299 patients)
DYSGEUSIA (299 patients)
NERVOUSNESS (297 patients)
DRUG EXPOSURE DURING PREGNANCY (297 patients)
IRRITABILITY (297 patients)
THROMBOSIS (296 patients)
COMA (296 patients)
OSTEONECROSIS OF JAW (294 patients)
PRODUCT QUALITY ISSUE (291 patients)
BLOOD BILIRUBIN INCREASED (289 patients)
DISTURBANCE IN ATTENTION (288 patients)
ANGINA PECTORIS (288 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (285 patients)
HEPATIC FAILURE (285 patients)
IMPAIRED HEALING (283 patients)
LYMPHADENOPATHY (283 patients)
HOT FLUSH (283 patients)
BLOOD UREA INCREASED (283 patients)
C-REACTIVE PROTEIN INCREASED (282 patients)
WHITE BLOOD CELL COUNT INCREASED (281 patients)
DYSPHONIA (279 patients)
DYSPNOEA EXERTIONAL (279 patients)
WHEEZING (279 patients)
HYPERTHYROIDISM (278 patients)
ELECTROCARDIOGRAM QT PROLONGED (277 patients)
SEPTIC SHOCK (276 patients)
GASTRITIS (276 patients)
FLATULENCE (276 patients)
STRESS (273 patients)
FEMUR FRACTURE (273 patients)
CATARACT (271 patients)
WRONG TECHNIQUE IN DRUG USAGE PROCESS (271 patients)
MIGRAINE (270 patients)

In addition to reviewing our up-to-date FDA research, users may interact with the FactMed community - currently one million members and growing! FactMed online research and discussions are read by patients, scientists, physicians, and other interested health care parties. Post follow up Questions to learn from our diverse readership. Likewise, patients who have experienced unwanted effects are encouraged to share their Concerns to help educate and inform our members.

Recent FactMed Activity for LEVOTHYROXINE SODIUM

Issue	Description / Topic	Timestamp
QUESTION PROTEIN S DEFICIENCY	Hi! Is it true that you should not take levothyroxine sodium 50mcg if you have protein S deficiency?	2014-11-29 12:11:29
QUESTION ALOPECIA SCARRING	I had a thyroid gland removed 30 years ago and have been on levothyroxine (1mg) since. I did not have any hair loss issues. A year or so ago my physician prescribed me 1.5 mg and 6 months ago I experienced the excessive hair loss. I scheduled 2 appointments with my physician but he didn't believe me and told me that I am spending too much time on the internet searching for connection between thyroid problems and hair loss. Approximately 4 months ago I started to have bold patches which I couldn't hide anymore and I started to wear a wig. My physician was shocked when I paid him a visit and finally sent me to see a dermatologist who performed a biopsy. The results come back and I was diagnosed with scarring alopecia. I'm wandering if the alopecia was triggered by excessive levothyroxine medication. My physician also prescribed me lower dosage of levothyroxine (1.25 mg) and after getting my blood test results decreased the dosage to 1.12 mg. I don't know if that dosage is still to high.	2014-12-12 19:50:28
QUESTION AORTIC DILATATION	is aort dilation of phenomenons of hypothyroidism or levothyroxine or none?	2015-01-05 13:11:53
QUESTION SUDDEN HEARING LOSS	Can levothyroxine cause the sudden deafness I am diebedic And only been on the levothyroxine for about 4months but l never had any hearing problems before this happened and its only my left ear	2015-02-11 20:35:56
QUESTION GOUT	Do levothyroxine cause gout	2015-02-19 11:46:32
QUESTION GOUT	Do levothyroxine cause gout	2015-02-19 11:50:14
QUESTION ASTHMA	I notice it is hearing change in one ear and also wheezing canLevothyroxine sodium cause that	2015-03-15 00:35:15
QUESTION GOUT	does levothyroxine cause gout	2015-03-18 14:10:19
QUESTION HYPOTHERMIA	since I have been on 50 mg/5 days a week of levothyroxine I have noticed that I am often cold and my skin feels clammy.	2015-04-03 19:45:14
QUESTION PURPURA	I too have developed purpura since being on levothyroxine 75mg daily. My doctors refuse to acknowledge that. The drug is the cause of this and therefore I am not getting any treatment should I ask to be referred and if so to whom.	2015-04-06 07:46:21
QUESTION CYP2D6 POLYMORPHISM	I am a poor metabolizer of CYP2D6. I have felt less tired since I have been on Levothyroxine 25 mg 1x a day but I have been noticing dry mouth and increased anxiety, tension, a tightness in my head which I attributed to sinus problems - but I am not sure about that any more.. I am beginning to think my symptoms are caused my the medicine.	2015-04-12 09:23:02
QUESTION GOUT	does levothyroxine cause gout	2015-05-18 07:21:59
QUESTION HAEMOCHROMATOSIS	I have recently been started on levothyroxine 25micrograms but am worried about taking them because i have Hemochromatosis, will this have any effect on the drug or my iron levels.	2015-05-26 04:38:39
QUESTION DRUG INTERACTION	Is ok to take levothyroxin 75mcg and nac n-acetyl-cysteine 1200mg	2015-06-06 18:34:48
QUESTION SUDDEN HEARING LOSS	Is hearing loss permanent from levothroxine	2015-06-13 17:49:59
QUESTION PAIN	I had an adverse drug interaction between levothyroxine and diazepam. For three years, I suffered terrible pain requiring morphine. I only found that taking them together was the cause by looking at an article from the Benzobuddies website. Everybody thought I was imagining the pain, apart from my Neuropsychiatrist.	2015-06-14 17:58:07
QUESTION SKIN HYPERPIGMENTATION	Does levothyroxine cause hyperpigmentation or malasma? I am taking a dosage of 88MCG daily for about five years. I have a presistent case of hyperpigmentation with dark splotches on my forehead, cheeks, chin, upper lip. I've tried various treatment but there is little to no improvement of this condition.	2015-09-02 01:32:39
QUESTION SKIN HYPERPIGMENTATION	Does levothyroxine cause hyperpigmentation or malasma? I am taking a dosage of 88MCG daily for about five years. I have a presistent case of hyperpigmentation with dark splotches on my forehead, cheeks, chin, upper lip. I've tried various treatment but there is little to no improvement of this condition.	2015-09-02 01:32:40
QUESTION SLEEP PARALYSIS	Levothyroxine is definetly causing me ISP - Isolated Sleep Paralysis and some mixed Lucid Dreaming with false awakening type II which is getting on my nerves, I have to wake up several times in order to really wake up, and to suddenly notice I'm paralyzed and hallucinating stuff. It started just as a took my first levo pill, same day, first ISP experience, later I started with the Lucid Dreaming, now what?	2015-09-24 12:50:28
QUESTION MYOTONIA	Is there any side effects of levothyroxine on someone who already has congenital myotonia?	2015-10-25 11:20:49
QUESTION AGE-RELATED MACULAR DEGENERATION	After 14 years of taking Levothyroxin I have beginning macular degeneration ..shall I change to another medication for hypothyroidism?	2015-11-30 03:11:07
QUESTION HAIR COLOUR CHANGES	i have been taking Levothyroxine 50 micrograms, for a number of years, but over the last 5 years i have been getting more and more black hair,i have been a silver white colour for about 10 years, my eyebrows were white and are now almost black. my hair was auburn when i was younger can levothyroxine be the cause.	2015-12-07 07:23:54
QUESTION BLADDER CANCER	I have been dealing w bladder cancer and wondering if the levothyroxin is the cause since I don't smoke and have a healthy diet.	2015-12-15 11:30:17
QUESTION BLADDER CANCER	I have been dealing w bladder cancer and wondering if the levothyroxin is the cause since I don't smoke and have a healthy diet.	2015-12-16 12:44:19
QUESTION BLADDER CANCER	I have been dealing w bladder cancer and wondering if the levothyroxin is the cause since I don't smoke and have a healthy diet.	2015-12-16 12:44:57
QUESTION DRUG INTERACTION	Can I take percocet with levothyroxin	2015-12-30 23:46:33
QUESTION DRUG INTERACTION	Can I take percocet with levothyroxin	2015-12-30 23:48:27
QUESTION BRAIN DAMAGE	Can brain fog resulting from using Levothyroxine cause damage to the brain in children?	2016-02-15 00:54:21
QUESTION TOOTH EXTRACTION	Iam taking Levothyroxine Ssodium, iam going to get two of my tooth pull today, can someone tell me is there sides affacts.	2016-02-18 11:38:03
QUESTION CHRONIC LYMPHOCYTIC LEUKAEMIA REFRACTORY	Has anyone taken this medication an now have lymphocytic leukaemia	2016-02-19 23:22:03
QUESTION BINGE EATING	Binge eating	2016-03-29 18:50:37
QUESTION DRUG INTERACTION	is a con mbination of levothyroxin 88mcg dangerous if taken with 5mg ambien?	2016-04-19 22:43:51
QUESTION BLOOD ALKALINE PHOSPHATASE DECREASED	Hi,last year I started by 50 mg and after 10 months ALP drop to 32(40-180) 2 months ago Doctor put me on 100 mg and now ALP is 29,please advise me if levotroxine caused this and if it's dangerous for bone	2016-04-29 03:11:28
QUESTION SUDDEN HEARING LOSS	My husband experienced permanent sudden sensorineural hearing loss in his left ear a few weeks after starting a low dose of levothyroxine. Is this a recognized side effect?	2016-06-02 07:40:16
QUESTION MYOPATHY	levothyroxine will ruin your life	2016-06-04 01:56:48
QUESTION DRUG INTERACTION	Can I take doxycycline hyclate 100 mg with levothyroxine? I alternate 100 and 112 mg of levothyroxine daily. I am to start the doxycycline twice a day. I plan to take both drugs an hour before my breakfast and then the other doxycycline 12 hours later. Thanks!	2016-06-13 21:49:50
QUESTION DRUG INTERACTION	Can I take doxycycline hyclate 100 mg with levothyroxine? I alternate 100 and 112 mg of levothyroxine daily. I am to start the doxycycline twice a day. I plan to take both drugs an hour before my breakfast and then the other doxycycline 12 hours later. Thanks!	2016-06-13 21:49:51
QUESTION DRUG INTERACTION	Can I take doxycycline hyclate 100 mg with levothyroxine? I alternate 100 and 112 mg of levothyroxine daily. I am to start the doxycycline twice a day. I plan to take both drugs an hour before my breakfast and then the other doxycycline 12 hours later. Thanks!	2016-06-13 21:49:51
QUESTION DRUG INTERACTION	Can I take doxycycline hyclate 100 mg with levothyroxine? I alternate 100 and 112 mg of levothyroxine daily. I am to start the doxycycline twice a day. I plan to take both drugs an hour before my breakfast and then the other doxycycline 12 hours later. Thanks!	2016-06-13 21:49:51
QUESTION DEMENTIA	I take Levothyroxine75MCG,everyday, could this could have lead to my hearing, my vision problem; and now my memory?	2016-06-29 17:34:07
QUESTION DEMENTIA	I take Levothyroxine75MCG,everyday, could this could have lead to my hearing, my vision problem; and now my memory?	2016-06-29 17:37:34
QUESTION NAIL GROWTH ABNORMAL	Hi I am prescribed levothyroxine and am wondering if it causes brittle nails and abnormal nail growth! My toe nails since starting the medication have become yellow in colour and very brittle!	2016-06-30 05:10:03
QUESTION HEPATITIS B POSITIVE	can we take hepatitis B vaccination along with levothyroxine medication	2016-09-30 08:46:34
QUESTION LICHEN PLANUS	I was diagnosed with lichen planus oral disease could this possibly be a reaction from levothyroxine	2016-11-13 18:12:38
QUESTION DRUG SCREEN FALSE POSITIVE	I am on levothyroxin and suboxone. Since starting the levothyroxine my urine screens are negative until sent to the lab where they are positive for cocaine, i do not use cocaine and i need to know why this is happening.	2016-11-22 19:58:42
QUESTION DRUG SCREEN FALSE POSITIVE	I am on levothyroxin and suboxone. Since starting the levothyroxine my urine screens are negative until sent to the lab where they are positive for cocaine, i do not use cocaine and i need to know why this is happening.	2016-11-22 20:00:22
QUESTION RHEUMATOID FACTOR POSITIVE	Hi, I have RF and ANA positive and negative both in the past two years. I am consuming Levothyroxid. Can it cause it as I may use different brand of it?	2016-11-23 13:08:11
QUESTION PARANOIA	My mom takes this medication Can this medication cause severe paranoia nd schizophrenia. Shes been on it for 10 years now from what she says	2016-11-25 15:31:05
QUESTION BURSITIS	Bursitis and levothyroxin? Correlations?	2017-01-08 22:16:35
CONCERN ROSACEA	Fungus and Rosacea after having thyroidectomy and larger dosage of levothyroxine	2017-01-21 23:56:38
QUESTION LYMPHOCYTIC LEUKAEMIA	My husband has been on levothyroxine for no more than 3 months. First blood test showed low thyroid reading and now his readings this time are WBC 110,000, lymphnodes 101, haemaglobin level 8.6 And dr is saying these readings on are par with leukaemia.......too coincidental after reading all the above. Due to see a haemotologist early next week. Has anyone else had these type of readings. Thanks	2017-01-23 15:34:48
QUESTION VAGINAL BURNING SENSATION	I have been taking levo 150 MG for two years since having thyroid cancer with no problem. Recently I changed pharmacies and they obviously get their medication from a different buyer, they are a different color and and shape. Every since I have been taking them I am experiencing a vaginal burning sensation. What shall I do.?	2017-01-28 16:18:30
QUESTION SYSTOLIC HYPERTENSION	My wife takes .88 mg of levothyroxine once per day at night but has been experiencing isolated systolic hypertension. It appears that those who believe that isolated systolic hypertension as it relates to levothyroxine are rather rare, e.g, 4 cases out of +/- 50,000. Does anyone care to comment on the relationship between .88 mg of levothyroxin and isolated systolic hypertension?	2017-02-08 09:41:20
QUESTION COUGH	I just started considering that my cough could be linked to taking levothyroxine.. I have been taking it for at least seven years or more and my cough despite seeing many Drs Ents pulmonologists and gastro specialists, trying many things including acupuncture inhalers nebulizers you name it to no avail! I cough at least a dozen times a day and am getting really disgusted with the cough interfering with my life! I have undergone numerous tests manometry etc . The last comment mentioned the person had hypertension and that brings up another thought about a reason I had a mini stroke. In the hospital the doctor said I had hypertension. All my other numbers sugar cholesterol and blood pressure were in check. Sometimes I cough for so long or really hard that I wrench my back or stomach. At one point I thought my cough was genetic because I sound just like my mother. She also was on thyroid med for majority of her life! I could find her in the store by her strong cough! Now my husband finds me by my strong cough. Currently I am seein a dr who diagnosed me with LSN. Laryngeal sensory neuropathy. Sorry for rambling I just trying to get this cough to go away! Lots of people saying levothyroxine may be a culprit!! I cough in am sometimes before I take Levothyroxine or it got so bad last December that I was up at least twice on any given night. The cough is so bad that now I cough almost after every meal I'm calling my current throat specialist first thing Monday morning! Thanks all for listening!	2017-02-10 23:14:06
QUESTION DRUG INTERACTION	Is it ok to take B-12 with Levothyroxine?	2017-02-11 12:22:44
QUESTION ANAEMIA	to your home. Â Here are the preceding posts if you’d like to catch up. Â Part one “Deciding What to Tackle First“, part two “Using the 5s Approach to Or8i2izataon&#g2n1; and part three	2017-03-20 08:35:49
QUESTION CHEST PAIN	My mom just gave me some dresses that I wore when I was a little girl. They were sewn for me by my great grmeadothnr. They are so sweet and I would love to add my personal touch to them by embroidering the hems and collars. I hope that my daughter will love them as much as I did.[]	2017-03-20 08:56:15
QUESTION DRUG INTERACTION	What are the interactions betwen levothyroxine and melicican and ciclobenzaprine?	2017-03-21 14:41:33
QUESTION MYALGIA	Приветствую пользователей ресурса! Представляем досуг с элитными девушками все подробности можно узнать по мылу dosug-elitei@mail.ru	2017-05-12 04:41:14

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