About this FactMed analysis covering adverse side effect reports of NORTRIPTYLINE HYDROCHLORIDE patients who developed MYASTHENIA GRAVIS CRISIS.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 4 individuals taking NORTRIPTYLINE HYDROCHLORIDE reported MYASTHENIA GRAVIS CRISIS to the FDA. A total of 276 NORTRIPTYLINE HYDROCHLORIDE drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between NORTRIPTYLINE HYDROCHLORIDE and MYASTHENIA GRAVIS CRISIS. In doing so, we compare NORTRIPTYLINE HYDROCHLORIDE with other drugs that cause MYASTHENIA GRAVIS CRISIS, to help you evaluate whether or not NORTRIPTYLINE HYDROCHLORIDE causes MYASTHENIA GRAVIS CRISIS. Likewise, this page shows the most highly-reported side effects of NORTRIPTYLINE HYDROCHLORIDE, so you can see if MYASTHENIA GRAVIS CRISIS ranks among NORTRIPTYLINE HYDROCHLORIDE's most well-known side effects.
Summary Statistics
Reports of NORTRIPTYLINE HYDROCHLORIDE causing MYASTHENIA GRAVIS CRISIS: 4
Reports of any side effect of NORTRIPTYLINE HYDROCHLORIDE : 276
Percentage of NORTRIPTYLINE HYDROCHLORIDE patients where MYASTHENIA GRAVIS CRISIS is a reported side effect: 1.4493%

FDA reports of any drug causing MYASTHENIA GRAVIS CRISIS : 71
Average percentage for all medicated patients where MYASTHENIA GRAVIS CRISIS is reported as a complication: 0.0004%

Physician opinion on NORTRIPTYLINE HYDROCHLORIDE as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing NORTRIPTYLINE HYDROCHLORIDE:
PRODUCT USED FOR UNKNOWN INDICATION ( 45 patients )
DRUG USE FOR UNKNOWN INDICATION ( 23 patients )
DEPRESSION ( 14 patients )
PAIN ( 7 patients )
MUSCLE SPASMS ( 3 patients )
ANXIETY ( 3 patients )
PSYCHOTIC DISORDER ( 3 patients )
INSOMNIA ( 3 patients )
MIGRAINE ( 3 patients )
NEUROPATHY PERIPHERAL ( 2 patients )
FIBROMYALGIA ( 2 patients )
NEURALGIA ( 2 patients )
ARTHRALGIA ( 2 patients )
IRRITABLE BOWEL SYNDROME ( 1 patients )
MENTAL DISORDER ( 1 patients )
COMPLEX REGIONAL PAIN SYNDROME ( 1 patients )
DRUG ABUSER ( 1 patients )
SMOKING CESSATION THERAPY ( 1 patients )
TEMPORAL ARTERITIS ( 1 patients )
MAJOR DEPRESSION ( 1 patients )
ANTIDEPRESSANT THERAPY ( 1 patients )
DEMENTIA ( 1 patients )
PROPHYLAXIS OF NAUSEA AND VOMITING ( 1 patients )
DIZZINESS ( 1 patients )
SLEEP DISORDER THERAPY ( 1 patients )
SYNCOPE ( 1 patients )
HEADACHE ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with MYASTHENIA GRAVIS CRISIS:

THYROLAR-1 (33 patients)
MESTINON (15 patients)
FORTEO (8 patients)
PYRIDOSTIGMINE BROMIDE (8 patients)
ACETAMINOPHEN (7 patients)
ERYTHROMYCIN (7 patients)
NEORAL (7 patients)
OMEPRAZOLE (7 patients)
TOPIRAMATE (7 patients)
ASPIRIN (6 patients)
KETEK (6 patients)
ALBUTEROL (5 patients)
HYDROCHLOROTHIAZIDE (5 patients)
SIMVASTATIN (5 patients)
AZATHIOPRINE (4 patients)
BIPERIDEN HYDROCHLORIDE TAB (4 patients)
CLOZAPINE (4 patients)
GLUCOPHAGE (4 patients)
HEPARIN (4 patients)
IPILIMUMAB (4 patients)
NORTRIPTYLINE HYDROCHLORIDE (4 patients)
PRAVASTATIN (4 patients)
PREDNISOLONE (4 patients)
PREDNISONE TAB (4 patients)
RIZATRIPTAN (4 patients)
THYROID TAB (4 patients)
VICODIN (4 patients)
TRAMADOL HCL (4 patients)
AMOXICILLIN (3 patients)
BICALUTAMIDE (3 patients)
CISPLATIN (3 patients)
COMBIVENT (3 patients)
CYMBALTA (3 patients)
DOXORUBICIN HCL (3 patients)
ETOPOSIDE (3 patients)
FLEXERIL (3 patients)
GRANDAXIN (TOFISOPAM) (3 patients)
LISINOPRIL (3 patients)
LUTEINIZING HORMONE RELEASANT (3 patients)
METAMIZOLE (3 patients)
METOCLOPRAMIDE (3 patients)
NITRODERM (3 patients)
PLACEBO (3 patients)
PREMARIN (3 patients)
PROGRAF (3 patients)
SPIRONOLACTONE (3 patients)
SUBOXONE (3 patients)
TIKOSYN (3 patients)
TORSEMIDE (3 patients)
TRILEPTAL (3 patients)
ALBUTEROL SULFATE (2 patients)
ASCORBIC ACID (2 patients)
ATENOLOL (2 patients)
AVANDIA (2 patients)
BAYASPIRIN TABLET (2 patients)
BISOPROLOL FUMARATE (2 patients)
CEFTRIAXONE SODIUM (2 patients)
CELLCEPT (2 patients)
CIPROFLOXACIN (2 patients)
DECADRON (2 patients)
DIART (AZOSEMIDE) TABLET (2 patients)
ENTECAVIR (2 patients)
HERBESSOR R (DILTIAZEM HYDROCHLORIDE) CAPSULE (2 patients)
INTERFERON BETA-1B (2 patients)
LEXAPRO (2 patients)
LIPITOR (2 patients)
MOBIC (2 patients)
MYTELASE (2 patients)
NABUMETONE (2 patients)
NORTRIPTYLINE HCL (2 patients)
NORVASC (2 patients)
ONDANSETRON (2 patients)
PARAMIDIN (BUCOLOME) CAPSULE (2 patients)
PREDNISONE (2 patients)
PREDONINE (2 patients)
PROTONIX (2 patients)
QUETIAPINE (2 patients)
ROSUVASTATIN (2 patients)
SEPAMIT CAPSULE (2 patients)
SOLU-MEDROL (2 patients)
WARFARIN SODIUM (2 patients)
STEROIDS NOS (2 patients)
SYNTHROID (2 patients)
TRAMADOL HYDROCHLORIDE (2 patients)
ADVAIR DISKUS 100/50 (1 patients)
ALBUTEROL SULFATE AUTOHALER (1 patients)
ALTACE (1 patients)
AMAREL (1 patients)
AMARYL (1 patients)
AMARYL (GLIMEPIRIDE) PER ORAL NOS (1 patients)
AMISULPRIDE (1 patients)
AMLOR (1 patients)
AMOBAN (ZOPICLONE) (1 patients)
ANAPEINE (1 patients)
ANASPAZ (1 patients)
ARIPIPRAZOLE (1 patients)
AVONEX (1 patients)
AZATHIOPRIN (AZATHIOPRIN) (1 patients)
AZITHROMYCIN (1 patients)
BASEN (VOGLIBOSE) PER ORAL NOS (1 patients)
BENAZEPRIL HYDROCHLORIDE (LOTENSIN) (1 patients)
BENICAR (1 patients)
BETIMOL (1 patients)
BEZATOL (BEZAFIBRATE) PER ORAL NOS (1 patients)
BIAXIN (1 patients)
BISOPROLOL (1 patients)
BLINDED: PLACEBO (1 patients)
BLOPRESS (CANDESARTAN CILEXETIL) PER ORAL NOS (1 patients)
BONALON (1 patients)
CALCIUM +VIT D (1 patients)
CALCIUM CARBONATE AND CHOLECALCIFEROL (1 patients)
CALCIUM GLUCONATE (1 patients)
CALCIUM WITH VITAMIN D (1 patients)
CARDIZEM (1 patients)
CARVEDILOL (1 patients)
CELEBREX (1 patients)
CLAMOXYL (1 patients)
COAPROVEL (1 patients)
DEXAMETHASONE (1 patients)
DIART (AZOSEMIDE) (1 patients)
DIDRONEL (1 patients)
DIGOXIN (1 patients)
DILTIAZEM (1 patients)
DOXYCYCLINE (1 patients)
DROPERIDOL (1 patients)
DULCOLAX (1 patients)
ECHINACEA (1 patients)
ENALAPRIL MALEATE (1 patients)
EVAMIST (1 patients)
FLONASE (1 patients)
FLUTICASONE FUROATE (1 patients)
FOSAMAX (1 patients)
GAMMAGARD LIQUID (1 patients)
GASTER D (1 patients)
GLAKAY (MENATETRENONE) (1 patients)
GLUTAMINE (1 patients)
HERBAL MEDICATIONS (1 patients)
HERBRESSOR R (DILTIZEM HYDROCHLORIDE) (1 patients)
HYDRALAZINE HCL (1 patients)
HYDROMORPHONE HYDROCHLORIDE (1 patients)
IMURAN (1 patients)
IPRATROPIUM /00391402/ (1 patients)
KARDEGIC (1 patients)
LABETALOL HCL (1 patients)
LACTINEX /00203201/ (1 patients)
LAMALINE (1 patients)
LANTUS (1 patients)
LANZOR (1 patients)
LASIX (1 patients)
LEVOPHED (1 patients)
LIPANTHYL (1 patients)
LOCHOL (LOVASTATIN) PER ORAL NOS (1 patients)
LOPID (1 patients)
LOPRESSOR (1 patients)
LORAZEPAM (1 patients)
LOVENOX (1 patients)
MAXZIDE (1 patients)
MESTINON (PYRIDOSTIGMINE BROMIDE) TABLET (1 patients)
METHIMAZOLE (1 patients)
METHYLPREDNISOLONE (1 patients)
MORPHINE HYDROCHLORIDE (1 patients)
MOTRIN IB (1 patients)
MUCINEX (1 patients)
MUCOSTA (REBAMIPIDE) (1 patients)
MULTIVITAMIN (1 patients)
MYCOSTATIN (1 patients)
MYLANTA (1 patients)
MYTELASE (AMBENONIUM CHLORIDE) PER ORAL NOS (1 patients)
NAUZELIN (1 patients)
NEOSPORIN /00038301/ (1 patients)
NORCO (1 patients)
NOREL DM /00417201/ (1 patients)
NOVOLOG (1 patients)
NYSTATIN (1 patients)
OCTAGAM (1 patients)
ONDANSETRON HCL (1 patients)
ONE-ALPHA (ALFACALCIDOL) (1 patients)
OSCAL (CALCIUM CARBONATE) (1 patients)
PANTOPRAZOLE (1 patients)
PARAMIDIN (BUCOLOME) (1 patients)
PAXIL (1 patients)
PHENERGAN HCL (1 patients)
PIOGLITAZONE HCL (1 patients)
ZOFRAN /00955302/ (1 patients)
POTASSIUM (1 patients)
POTASSIUM GLUCONATE TAB (1 patients)
PREDNISONE /00044701/ (1 patients)
PREMARIN (ESTROGENS COJUGATED) (1 patients)
PYRIDOSTIGMINE BROMIDE(PYRIDOSTIGMINE BROMIDE) TABLET, 60MG (1 patients)
QUINAPRIL (1 patients)
RESTORIL (1 patients)
RILMENIDINE (1 patients)
RIZATRIPTAN (RIZATRIPTAN) (1 patients)
RIZATRIPTAN(RIZATRIPTAN) (1 patients)
ROCEPHIN (1 patients)
ROZEREM (1 patients)
SEPAMIT (1 patients)
SERMION (1 patients)
SEVOFLURANE (1 patients)
SODIUM CHLORIDE (1 patients)
STOGAR (LAFUTIDINE) PER ORAL NOS (1 patients)
SUTENT (1 patients)
TACROLIMUS (1 patients)
TACROLIMUS CAPSULES (TACROLIMUS CAPSULES) (1 patients)
TACROLIMUS CAPSULES (TACROLIMUS CAPSULES) CAPSULE (1 patients)
TACROLIMUS CAPSULES(TACROLIMUS CAPSULES) CAPSULE (1 patients)
TAMSULOSINE (1 patients)
TAPAZOLE (1 patients)
TARCEVA (1 patients)
THAMYLAL (1 patients)
Most common side effects for patients taking NORTRIPTYLINE HYDROCHLORIDE:
PAIN (35 patients)
ANXIETY (28 patients)
COMPLETED SUICIDE (28 patients)
FATIGUE (27 patients)
DYSPNOEA (25 patients)
BACK PAIN (24 patients)
SOMNOLENCE (22 patients)
OSTEOMYELITIS (19 patients)
RIB FRACTURE (18 patients)
DEATH (18 patients)
WEIGHT DECREASED (18 patients)
OSTEOARTHRITIS (17 patients)
HYPOAESTHESIA (17 patients)
PARAESTHESIA (16 patients)
PAIN IN EXTREMITY (16 patients)
PAIN IN JAW (16 patients)
NAUSEA (15 patients)
CHEST PAIN (15 patients)
HYPERTENSION (15 patients)
INJURY (15 patients)
INTERVERTEBRAL DISC DEGENERATION (14 patients)
DEEP VEIN THROMBOSIS (14 patients)
DYSPHAGIA (14 patients)
TOXICITY TO VARIOUS AGENTS (13 patients)
CARDIAC DISORDER (13 patients)
MYALGIA (13 patients)
TOOTH EXTRACTION (13 patients)
DIARRHOEA (13 patients)
DRUG INEFFECTIVE (13 patients)
INSOMNIA (13 patients)
OSTEONECROSIS (12 patients)
ARTHRALGIA (12 patients)
CONSTIPATION (12 patients)
ENDODONTIC PROCEDURE (12 patients)
PULMONARY EMBOLISM (11 patients)
NEURALGIA (11 patients)
LOSS OF CONSCIOUSNESS (11 patients)
NEUROPATHY PERIPHERAL (11 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (11 patients)
ARTHRITIS (10 patients)
MUSCULOSKELETAL STIFFNESS (10 patients)
LOOSE TOOTH (10 patients)
BURSITIS (10 patients)
COMPRESSION FRACTURE (10 patients)
DECREASED APPETITE (10 patients)
DENTURE WEARER (10 patients)
DIABETES MELLITUS (10 patients)
TOOTH EROSION (10 patients)
PROSTATISM (10 patients)
DYSGEUSIA (10 patients)
PERIODONTAL DISEASE (10 patients)
FALL (10 patients)
GINGIVAL BLEEDING (10 patients)
HAIR GROWTH ABNORMAL (10 patients)
AGITATION (9 patients)
TACHYCARDIA (9 patients)
CARDIAC ARREST (9 patients)
CARDIO-RESPIRATORY ARREST (9 patients)
HOT FLUSH (9 patients)
SWELLING (9 patients)
ORAL PAIN (9 patients)
RENAL FAILURE CHRONIC (9 patients)
THROMBOSIS (9 patients)
GAIT DISTURBANCE (9 patients)
SPINAL COLUMN STENOSIS (8 patients)
JOINT LOCK (8 patients)
APHTHOUS STOMATITIS (8 patients)
HERPES ZOSTER (8 patients)
ASPHYXIA (8 patients)
ASTHENIA (8 patients)
SPONDYLOLISTHESIS (8 patients)
OEDEMA (8 patients)
PULMONARY HYPERTENSION (8 patients)
MUSCULOSKELETAL DISCOMFORT (8 patients)
CONTUSION (8 patients)
CYST (8 patients)
DECREASED INTEREST (8 patients)
DEHYDRATION (8 patients)
DEPRESSED MOOD (8 patients)
DIVERTICULITIS (8 patients)
DIVERTICULUM (8 patients)
DIZZINESS (8 patients)
THYROID DISORDER (8 patients)
OTITIS MEDIA ACUTE (8 patients)
TENDONITIS (8 patients)
HYPOXIA (8 patients)
HAEMATEMESIS (8 patients)
KNEE ARTHROPLASTY (8 patients)
PHARYNGEAL OEDEMA (7 patients)
ABDOMINAL PAIN UPPER (7 patients)
RESPIRATORY TRACT INFECTION (7 patients)
MYOCARDIAL INFARCTION (7 patients)
BLOOD CHOLESTEROL INCREASED (7 patients)
BONE LESION (7 patients)
OSTEONECROSIS OF JAW (7 patients)
OVERDOSE (7 patients)
VOMITING (7 patients)
IMPAIRED HEALING (7 patients)
RESPIRATORY DEPRESSION (7 patients)
SINUSITIS (7 patients)
STOMATITIS (7 patients)
DENTAL OPERATION (7 patients)
OEDEMA PERIPHERAL (7 patients)
TREMOR (7 patients)
FLUSHING (7 patients)
SPINAL DISORDER (7 patients)
MULTI-ORGAN FAILURE (7 patients)
ABDOMINAL PAIN (6 patients)
ACCIDENTAL OVERDOSE (6 patients)
RED BLOOD CELL SEDIMENTATION RATE INCREASED (6 patients)
INFLUENZA LIKE ILLNESS (6 patients)
NASAL DISCOMFORT (6 patients)
BLOOD IMMUNOGLOBULIN A INCREASED (6 patients)
BLOOD IMMUNOGLOBULIN G INCREASED (6 patients)
HYPOTENSION (6 patients)
HYPERTONIC BLADDER (6 patients)
VISION BLURRED (6 patients)
SYNOVIAL CYST (6 patients)
COUGH (6 patients)
INJECTION SITE PAIN (6 patients)
INCORRECT DOSE ADMINISTERED (6 patients)
RENAL FAILURE ACUTE (6 patients)
FEELING ABNORMAL (6 patients)
HEADACHE (6 patients)
MULTIPLE DRUG OVERDOSE INTENTIONAL (6 patients)
SUICIDE ATTEMPT (5 patients)
ABSCESS DRAINAGE (5 patients)
ACTINOMYCOSIS (5 patients)
MYELOMA RECURRENCE (5 patients)
APICECTOMY (5 patients)
BONE PAIN (5 patients)
CENTRAL VENOUS CATHETERISATION (5 patients)
INTERVERTEBRAL DISC PROTRUSION (5 patients)
HEART RATE INCREASED (5 patients)
CONFUSIONAL STATE (5 patients)
DEPRESSION (5 patients)
DIABETIC KETOACIDOSIS (5 patients)
DIABETIC NEUROPATHY (5 patients)
DRUG INTERACTION (5 patients)
TYPE 2 DIABETES MELLITUS (5 patients)
DYSPHONIA (5 patients)
MALAISE (5 patients)
METASTASES TO BONE (5 patients)
LETHARGY (5 patients)
ACCIDENTAL EXPOSURE (4 patients)
URINARY TRACT INFECTION (4 patients)
HYPOACUSIS (4 patients)
LONG QT SYNDROME (4 patients)
PERIODIC LIMB MOVEMENT DISORDER (4 patients)
VENTRICULAR EXTRASYSTOLES (4 patients)
AUTOLOGOUS BONE MARROW TRANSPLANTATION THERAPY (4 patients)
INTRAOCULAR LENS IMPLANT (4 patients)
STEM CELL TRANSPLANT (4 patients)
SPINAL CORD COMPRESSION (4 patients)
BLOOD PRESSURE DECREASED (4 patients)
BLOOD PRESSURE INCREASED (4 patients)
BLOOD THYROID STIMULATING HORMONE INCREASED (4 patients)
BLOOD TRIGLYCERIDES INCREASED (4 patients)
THROAT TIGHTNESS (4 patients)
BRUGADA SYNDROME (4 patients)
INTERNATIONAL NORMALISED RATIO DECREASED (4 patients)
CATARACT OPERATION (4 patients)
VENTRICULAR TACHYCARDIA (4 patients)
IRRITABLE BOWEL SYNDROME (4 patients)
CHOLELITHIASIS (4 patients)
SLEEP APNOEA SYNDROME (4 patients)
CONVULSION (4 patients)
MYASTHENIA GRAVIS CRISIS (4 patients)
SUPRAVENTRICULAR EXTRASYSTOLES (4 patients)
DEPENDENCE (4 patients)
DIABETES MELLITUS INADEQUATE CONTROL (4 patients)
HYPERPROLACTINAEMIA (4 patients)
VISUAL IMPAIRMENT (4 patients)
VISUAL DISTURBANCE (4 patients)
DYSPNOEA PAROXYSMAL NOCTURNAL (4 patients)
IMPAIRED GASTRIC EMPTYING (4 patients)
RENAL FAILURE (4 patients)
ERYTHEMA (4 patients)
SPINAL CORD OPERATION (4 patients)
MACULOPATHY (4 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (4 patients)
LEUKOPENIA (4 patients)
MUSCULAR WEAKNESS (3 patients)
PEPTIC ULCER (3 patients)
PYREXIA (3 patients)
ANGIOEDEMA (3 patients)
ARTERIOSCLEROSIS (3 patients)
JOINT SWELLING (3 patients)
BENIGN PROSTATIC HYPERPLASIA (3 patients)
BILE DUCT OBSTRUCTION (3 patients)
BLOOD SODIUM DECREASED (3 patients)
CERVICOBRACHIAL SYNDROME (3 patients)
CHOLECYSTITIS (3 patients)
MUSCULOSKELETAL PAIN (3 patients)
COLLAPSE OF LUNG (3 patients)
SUICIDAL IDEATION (3 patients)
SINUS DISORDER (3 patients)
DEMENTIA ALZHEIMER'S TYPE (3 patients)
PERIORBITAL HAEMATOMA (3 patients)
EMOTIONAL DISTRESS (3 patients)
INTESTINAL FUNCTIONAL DISORDER (3 patients)
EYE HAEMORRHAGE (3 patients)
RESPIRATORY FAILURE (3 patients)
IRRITABILITY (3 patients)
FEELING HOT (3 patients)
FEMUR FRACTURE (3 patients)
GALLBLADDER NON-FUNCTIONING (3 patients)
GANGRENE (3 patients)
SINUS TACHYCARDIA (3 patients)
HAEMORRHAGE (3 patients)

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QUESTION
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