About this FactMed analysis covering adverse side effect reports of PACERONE patients who developed AKINESIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 2 individuals taking PACERONE reported AKINESIA to the FDA. A total of 941 PACERONE drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between PACERONE and AKINESIA. In doing so, we compare PACERONE with other drugs that cause AKINESIA, to help you evaluate whether or not PACERONE causes AKINESIA. Likewise, this page shows the most highly-reported side effects of PACERONE, so you can see if AKINESIA ranks among PACERONE's most well-known side effects.
Summary Statistics
Reports of PACERONE causing AKINESIA: 2
Reports of any side effect of PACERONE : 941
Percentage of PACERONE patients where AKINESIA is a reported side effect: 0.2125%

FDA reports of any drug causing AKINESIA : 753
Average percentage for all medicated patients where AKINESIA is reported as a complication: 0.0047%

Physician opinion on PACERONE as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing PACERONE:
ATRIAL FIBRILLATION ( 118 patients )
ARRHYTHMIA ( 48 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 44 patients )
DRUG USE FOR UNKNOWN INDICATION ( 24 patients )
HEART RATE IRREGULAR ( 21 patients )
CARDIAC DISORDER ( 20 patients )
VENTRICULAR FIBRILLATION ( 16 patients )
VENTRICULAR TACHYCARDIA ( 11 patients )
CARDIAC FIBRILLATION ( 7 patients )
HEART RATE INCREASED ( 4 patients )
CARDIAC FAILURE CONGESTIVE ( 4 patients )
VENTRICULAR ARRHYTHMIA ( 4 patients )
HYPERTENSION ( 3 patients )
SICK SINUS SYNDROME ( 3 patients )
CARDIAC ABLATION ( 2 patients )
PALPITATIONS ( 2 patients )
VENTRICULAR EXTRASYSTOLES ( 2 patients )
HEART RATE ABNORMAL ( 2 patients )
BRADYCARDIA ( 2 patients )
ILL-DEFINED DISORDER ( 1 patients )
PULSE ABNORMAL ( 1 patients )
CARDIAC OPERATION ( 1 patients )
SURGERY ( 1 patients )
CORONARY ARTERY SURGERY ( 1 patients )
DRUG TOXICITY ( 1 patients )
HYPERTHYROIDISM ( 1 patients )
MYOCARDIAL INFARCTION ( 1 patients )
CARDIOVERSION ( 1 patients )
DISEASE RECURRENCE ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with AKINESIA:

MODOPAR (292 patients)
EFFEXOR (145 patients)
XANAX (129 patients)
VIOXX (116 patients)
STALEVO 100 (111 patients)
ASPIRIN (73 patients)
PERGOLIDE MESYLATE (56 patients)
SINEMET (55 patients)
RISPERDAL (54 patients)
ATHYMIL (52 patients)
COMTAN (45 patients)
MADOPAR (41 patients)
LORAZEPAM (40 patients)
MADOPAR DISPERSIBLE (39 patients)
IMOVANE (38 patients)
ZYPREXA (37 patients)
ATARAX (37 patients)
VALPROATE SODIUM (36 patients)
CLOZAPINE (31 patients)
DEPAKOTE (30 patients)
CITALOPRAM HYDROBROMIDE (29 patients)
CLOBAZAM (29 patients)
FUROSEMIDE (28 patients)
REQUIP (28 patients)
PARLODEL (27 patients)
EXELON (27 patients)
PAXIL (26 patients)
DIGOXIN (25 patients)
LASIX (25 patients)
ERYTHROMYCIN (25 patients)
SEROQUEL (25 patients)
LAMOTRIGINE (25 patients)
RISPERIDONE (24 patients)
GENTAMICIN (24 patients)
PHENYTOIN (23 patients)
AMANTADINE HCL (23 patients)
ACETAMINOPHEN (21 patients)
HALDOL (21 patients)
DIAZEPAM (20 patients)
VALTREX (20 patients)
OMEPRAZOLE (19 patients)
PAROXETINE HCL (19 patients)
ACETAMINOPHEN AND TRAMADOL HCL (18 patients)
CEFOTAXIME (18 patients)
SPIRONOLACTONE (18 patients)
LEVOTHYROXINE SODIUM (18 patients)
TEGRETOL (17 patients)
PREDNISOLONE (17 patients)
DEPAKENE (17 patients)
HALOPERIDOL (17 patients)
SIMVASTATIN (16 patients)
NITROGLYCERIN (16 patients)
ZOLOFT (15 patients)
PIPERACILLIN (15 patients)
LIPITOR (15 patients)
LEXOMIL (14 patients)
CLOPIDOGREL (14 patients)
OLANZAPINE (14 patients)
CABERGOLINE (14 patients)
TEMESTA (14 patients)
CLONAZEPAM (14 patients)
IBUPROFEN (14 patients)
NEURONTIN (13 patients)
LEVODOPA (13 patients)
WARFARIN SODIUM (13 patients)
SERENACE (13 patients)
OXYCONTIN (13 patients)
MEMANTINE HCL (13 patients)
ATENOLOL (13 patients)
DIOVAN (12 patients)
HIZENTRA (12 patients)
PRAMIPEXOLE DIHYDROCHLORIDE (12 patients)
ALBUTEROL (12 patients)
CELEBREX (12 patients)
HEPARIN (12 patients)
SEROQUEL XR (12 patients)
ENOXAPARIN SODIUM (12 patients)
ATORVASTATIN CALCIUM (12 patients)
ABILIFY (11 patients)
PLAVIX (11 patients)
FLUOXETINE (11 patients)
LOXAPINE HCL (11 patients)
COREG (11 patients)
TAXOTERE (11 patients)
GLEEVEC (11 patients)
VENLAFAXINE (11 patients)
PREVACID (11 patients)
CAPTOPRIL (11 patients)
CIPRO (11 patients)
CYCLOSPORINE (11 patients)
LANTUS (10 patients)
SYNTHROID (10 patients)
ACTONEL (10 patients)
MIRAPEX (10 patients)
KETOCONAZOLE (10 patients)
ANTIBIOTICS (10 patients)
ARICEPT (10 patients)
HEPARIN SODIUM INJECTION (10 patients)
AVONEX (10 patients)
RAMIPRIL (9 patients)
INSULIN (9 patients)
NECYRANE (9 patients)
MORPHINE (9 patients)
FERROUS SULFATE TAB (9 patients)
PRAZEPAM (9 patients)
DONEPEZIL HCL (9 patients)
CARBOCISTEINE (9 patients)
EXTAVIA (9 patients)
BROMOCRIPTINE MESYLATE (9 patients)
AMBIEN (9 patients)
AMOXICILLIN (9 patients)
RISPERDAL CONSTA (9 patients)
LAMICTAL (9 patients)
SINGULAIR (9 patients)
ECONAZOLE NITRATE (9 patients)
ARTANE (9 patients)
FOLIC ACID (9 patients)
PRAMIPEXOLE DIHYCHLLORIDE (9 patients)
LISINOPRIL (9 patients)
CEFUROXIME (9 patients)
LYSOPAINE (9 patients)
PRILOSEC (9 patients)
HYDROCHLOROTHIAZIDE (9 patients)
SANDIMMUNE (9 patients)
CYMBALTA (8 patients)
ELUDRIL (8 patients)
MIRTAZAPINE (8 patients)
SOLANAX (8 patients)
EPINEPHRINE (8 patients)
TYLENOL (CAPLET) (8 patients)
CIATYL Z (8 patients)
TRAMAL (8 patients)
AMIODARONE HCL (8 patients)
COUMADIN (8 patients)
NEUROCIL (8 patients)
OXAZEPAM (8 patients)
LEVEMIR (8 patients)
AVANDIA (8 patients)
NEXIUM (8 patients)
PROTONIX (8 patients)
ZOCOR (8 patients)
WELLBUTRIN (8 patients)
BIPERIDEN HYDROCHLORIDE TAB (8 patients)
METFORMIN HCL (7 patients)
NORVASC (7 patients)
METOPROLOL (7 patients)
TRIVASTAL (7 patients)
ZANAFLEX (7 patients)
HUMIRA (7 patients)
ALDACTONE (7 patients)
SOLU-CORTEF (7 patients)
ALLOPURINOL (7 patients)
TRIHEXYPHENIDYL HCL (7 patients)
PREVISCAN (7 patients)
DOPAMINE HCL (7 patients)
SERTRALINE HCL (7 patients)
THIOPENTAL SODIUM (7 patients)
ENALAPRIL MALEATE (7 patients)
BISOPROLOL FUMARATE (7 patients)
TRAZODONE HCL (7 patients)
LITHIUM CARBONATE (7 patients)
TYLENOL (7 patients)
TRANXENE (7 patients)
POTASSIUM CHLORIDE (7 patients)
CEFOTAXIME SODIUM (7 patients)
PREDONINE (7 patients)
ISOSORBIDE DINITRATE (7 patients)
CYTARABINE (7 patients)
VITAMIN D (7 patients)
CARBIDOPA AND LEVODOPA (6 patients)
LOVENOX (6 patients)
ACETYLSALICYLIC ACID SRT (6 patients)
ESCITALOPRAM (6 patients)
DEXAMETHASONE TAB (6 patients)
SERTRALINE HYDROCHLORIDE (6 patients)
EVEROLIMUS (6 patients)
TASMAR (6 patients)
ALPRAZOLAM (6 patients)
MANTADIX (6 patients)
PRAZINE (6 patients)
HERCEPTIN (6 patients)
DEROXAT (6 patients)
AMLODIPINE (6 patients)
METHYLPREDNISOLONE (6 patients)
PURSENNID (6 patients)
REMICADE (6 patients)
SILECE (6 patients)
ZOVIRAX (6 patients)
MYCOPHENOLATE MOFETIL (6 patients)
ARAVA (6 patients)
LEPTICUR (6 patients)
CARBAMAZEPINE (6 patients)
TOBRAMYCIN (6 patients)
SYMMETREL (6 patients)
ATIVAN (6 patients)
ATORVASTATIN (6 patients)
CIPRALEX (ESCITALOPRAM) (6 patients)
LYRICA (6 patients)
CLARITHROMYCIN (6 patients)
CITALOPRAM (6 patients)
VANCOMYCIN (6 patients)
HEPTAMINOL (6 patients)
AZILECT (6 patients)
HUMALOG (6 patients)
PREDNISONE TAB (6 patients)
PROPRANOLOL (6 patients)
PROCTOLOG (6 patients)
INTETRIX (6 patients)
RANITIDINE (6 patients)
MS CONTIN (5 patients)
Most common side effects for patients taking PACERONE:
ATRIAL FIBRILLATION (167 patients)
DYSPNOEA (152 patients)
CARDIAC FAILURE CONGESTIVE (137 patients)
PAIN (131 patients)
NAUSEA (125 patients)
DIZZINESS (109 patients)
ASTHENIA (108 patients)
ANXIETY (107 patients)
HYPERTENSION (105 patients)
PNEUMONIA (96 patients)
ECONOMIC PROBLEM (95 patients)
FALL (94 patients)
HYPOTENSION (87 patients)
FATIGUE (81 patients)
INJURY (79 patients)
CHEST PAIN (78 patients)
ANAEMIA (75 patients)
VOMITING (74 patients)
ANHEDONIA (72 patients)
DEPRESSION (72 patients)
MULTIPLE INJURIES (68 patients)
HEADACHE (65 patients)
RENAL FAILURE ACUTE (63 patients)
DIARRHOEA (63 patients)
CORONARY ARTERY DISEASE (62 patients)
MYOCARDIAL INFARCTION (60 patients)
DEHYDRATION (56 patients)
PALPITATIONS (55 patients)
THERAPEUTIC AGENT TOXICITY (54 patients)
ARTHRALGIA (54 patients)
OEDEMA PERIPHERAL (53 patients)
MITRAL VALVE INCOMPETENCE (53 patients)
BRADYCARDIA (47 patients)
ABDOMINAL PAIN (46 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (46 patients)
RENAL FAILURE (46 patients)
PULMONARY FIBROSIS (46 patients)
COUGH (45 patients)
WEIGHT DECREASED (44 patients)
ARRHYTHMIA (44 patients)
MALAISE (44 patients)
BLOOD GLUCOSE INCREASED (44 patients)
WEIGHT INCREASED (43 patients)
PAIN IN EXTREMITY (43 patients)
SYNCOPE (42 patients)
CEREBROVASCULAR ACCIDENT (42 patients)
HYPOKALAEMIA (41 patients)
BACK PAIN (41 patients)
INSOMNIA (41 patients)
CARDIOMEGALY (41 patients)
TREMOR (40 patients)
CONFUSIONAL STATE (40 patients)
DEATH (39 patients)
ATRIAL FLUTTER (39 patients)
CARDIOMYOPATHY (39 patients)
MUSCULAR WEAKNESS (38 patients)
URINARY TRACT INFECTION (37 patients)
GAIT DISTURBANCE (37 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (37 patients)
BRONCHITIS (37 patients)
VENTRICULAR TACHYCARDIA (37 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (37 patients)
EMOTIONAL DISTRESS (36 patients)
HEART RATE DECREASED (35 patients)
DIABETES MELLITUS (35 patients)
PYREXIA (34 patients)
CONSTIPATION (34 patients)
HYPOTHYROIDISM (34 patients)
CONDITION AGGRAVATED (33 patients)
PARAESTHESIA (33 patients)
BALANCE DISORDER (33 patients)
CHEST DISCOMFORT (32 patients)
DECREASED APPETITE (32 patients)
CARDIAC ARREST (32 patients)
MENTAL STATUS CHANGES (31 patients)
SLEEP APNOEA SYNDROME (31 patients)
ATELECTASIS (31 patients)
PLEURAL EFFUSION (31 patients)
CELLULITIS (31 patients)
SINUSITIS (31 patients)
THROMBOCYTOPENIA (30 patients)
HEART RATE INCREASED (30 patients)
UNEVALUABLE EVENT (30 patients)
PULMONARY TOXICITY (30 patients)
MUSCLE SPASMS (29 patients)
PULMONARY OEDEMA (29 patients)
HYPOAESTHESIA (29 patients)
ATRIOVENTRICULAR BLOCK COMPLETE (29 patients)
VISION BLURRED (29 patients)
BLOOD PRESSURE DECREASED (29 patients)
ABDOMINAL PAIN UPPER (28 patients)
HYPERLIPIDAEMIA (28 patients)
MYOCARDIAL ISCHAEMIA (28 patients)
LOSS OF CONSCIOUSNESS (28 patients)
CATARACT (28 patients)
TACHYCARDIA (27 patients)
DYSPHAGIA (27 patients)
OSTEOMYELITIS (27 patients)
HAEMORRHAGE (26 patients)
RESPIRATORY FAILURE (26 patients)
LETHARGY (26 patients)
NEPHROLITHIASIS (26 patients)
FEELING ABNORMAL (26 patients)
LEFT VENTRICULAR DYSFUNCTION (25 patients)
ILL-DEFINED DISORDER (25 patients)
ACUTE MYOCARDIAL INFARCTION (25 patients)
HYPOPHAGIA (25 patients)
SEPSIS (24 patients)
CARDIAC DISORDER (24 patients)
UPPER RESPIRATORY TRACT INFECTION (24 patients)
PULMONARY CONGESTION (23 patients)
SPINAL OSTEOARTHRITIS (23 patients)
DYSPNOEA EXERTIONAL (23 patients)
SOMNOLENCE (23 patients)
OSTEONECROSIS OF JAW (23 patients)
ALOPECIA (22 patients)
ANGINA PECTORIS (22 patients)
FEAR (22 patients)
HYPOXIA (22 patients)
RENAL FAILURE CHRONIC (21 patients)
PLATELET COUNT DECREASED (21 patients)
AORTIC VALVE INCOMPETENCE (21 patients)
ARTHRITIS (21 patients)
DRUG INTERACTION (21 patients)
WHEEZING (21 patients)
CARDIAC MURMUR (21 patients)
BLINDNESS (21 patients)
ABASIA (20 patients)
MYALGIA (20 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (20 patients)
CARDIAC FAILURE (20 patients)
EPISTAXIS (20 patients)
DRUG INEFFECTIVE (20 patients)
MUSCULOSKELETAL CHEST PAIN (20 patients)
LUNG DISORDER (20 patients)
NECK PAIN (20 patients)
VENTRICULAR FIBRILLATION (20 patients)
DEAFNESS (20 patients)
OBESITY (20 patients)
HYPOMAGNESAEMIA (19 patients)
HEART RATE IRREGULAR (19 patients)
CARDIAC VALVE DISEASE (19 patients)
PULMONARY HYPERTENSION (19 patients)
TRICUSPID VALVE INCOMPETENCE (19 patients)
DYSPHONIA (18 patients)
CONTUSION (18 patients)
LUNG INFILTRATION (18 patients)
HYPERKALAEMIA (18 patients)
SINUS BRADYCARDIA (18 patients)
SURGERY (18 patients)
RASH (18 patients)
OSTEOARTHRITIS (18 patients)
VERTIGO (18 patients)
TRANSIENT ISCHAEMIC ATTACK (17 patients)
MULTI-ORGAN FAILURE (17 patients)
RHINITIS ALLERGIC (17 patients)
STRESS (17 patients)
OROPHARYNGEAL PAIN (17 patients)
DELIRIUM (17 patients)
ATRIOVENTRICULAR BLOCK FIRST DEGREE (17 patients)
RESPIRATORY DISTRESS (17 patients)
PERIPHERAL VASCULAR DISORDER (17 patients)
RENAL CYST (17 patients)
TINNITUS (17 patients)
MENTAL DISORDER (17 patients)
OEDEMA (17 patients)
DILATATION VENTRICULAR (17 patients)
METASTASES TO BONE (17 patients)
DRUG TOXICITY (16 patients)
CARDIO-RESPIRATORY ARREST (16 patients)
DISORIENTATION (16 patients)
EJECTION FRACTION DECREASED (16 patients)
LEFT VENTRICULAR HYPERTROPHY (16 patients)
ERYTHEMA (16 patients)
IMPAIRED HEALING (16 patients)
RHINITIS (16 patients)
BLOOD PRESSURE INCREASED (16 patients)
HEMIPARESIS (15 patients)
GASTRITIS (15 patients)
DYSPEPSIA (15 patients)
VENTRICULAR EXTRASYSTOLES (15 patients)
LABORATORY TEST ABNORMAL (15 patients)
SUPRAVENTRICULAR TACHYCARDIA (15 patients)
AORTIC STENOSIS (15 patients)
SEPTIC SHOCK (15 patients)
GASTROENTERITIS (15 patients)
PRURITUS (15 patients)
ASCITES (15 patients)
NERVOUSNESS (15 patients)
BLOOD POTASSIUM DECREASED (15 patients)
HYPERHIDROSIS (15 patients)
DRUG HYPERSENSITIVITY (14 patients)
HEPATIC ENZYME INCREASED (14 patients)
MUSCULOSKELETAL PAIN (14 patients)
DYSLIPIDAEMIA (14 patients)
EXCORIATION (14 patients)
HYPONATRAEMIA (14 patients)
SKIN DISCOLOURATION (13 patients)
HAEMATURIA (13 patients)
DISABILITY (13 patients)
HYPERCHOLESTEROLAEMIA (13 patients)
ISCHAEMIA (13 patients)
SPEECH DISORDER (13 patients)
CHOLELITHIASIS (13 patients)
VISUAL IMPAIRMENT (13 patients)
HAEMOGLOBIN DECREASED (13 patients)
TOXICITY TO VARIOUS AGENTS (13 patients)
SCAR (13 patients)
CAROTID ARTERY STENOSIS (13 patients)
HYPERTHYROIDISM (13 patients)

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