About this FactMed analysis covering adverse side effect reports of PHENYTOIN patients who developed ACANTHOLYSIS.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 1 individuals taking PHENYTOIN reported ACANTHOLYSIS to the FDA. A total of 7695 PHENYTOIN drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between PHENYTOIN and ACANTHOLYSIS. In doing so, we compare PHENYTOIN with other drugs that cause ACANTHOLYSIS, to help you evaluate whether or not PHENYTOIN causes ACANTHOLYSIS. Likewise, this page shows the most highly-reported side effects of PHENYTOIN, so you can see if ACANTHOLYSIS ranks among PHENYTOIN's most well-known side effects.
Summary Statistics
Reports of PHENYTOIN causing ACANTHOLYSIS: 1
Reports of any side effect of PHENYTOIN : 7695
Percentage of PHENYTOIN patients where ACANTHOLYSIS is a reported side effect: 0.0130%

FDA reports of any drug causing ACANTHOLYSIS : 33
Average percentage for all medicated patients where ACANTHOLYSIS is reported as a complication: 0.0002%

Physician opinion on PHENYTOIN as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing PHENYTOIN:
CONVULSION ( 1322 patients )
EPILEPSY ( 939 patients )
DRUG USE FOR UNKNOWN INDICATION ( 318 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 236 patients )
CONVULSION PROPHYLAXIS ( 203 patients )
GRAND MAL CONVULSION ( 163 patients )
STATUS EPILEPTICUS ( 153 patients )
PROPHYLAXIS ( 93 patients )
ILL-DEFINED DISORDER ( 65 patients )
PARTIAL SEIZURES ( 23 patients )
INFANTILE SPASMS ( 18 patients )
COMPLEX PARTIAL SEIZURES ( 17 patients )
DRUG EXPOSURE DURING PREGNANCY ( 16 patients )
CEREBROVASCULAR ACCIDENT ( 14 patients )
PROPHYLAXIS OF NAUSEA AND VOMITING ( 12 patients )
FRONTAL LOBE EPILEPSY ( 11 patients )
GLIOBLASTOMA MULTIFORME ( 10 patients )
TEMPORAL LOBE EPILEPSY ( 9 patients )
METASTASES TO CENTRAL NERVOUS SYSTEM ( 9 patients )
MENINGIOMA ( 8 patients )
HEAD INJURY ( 8 patients )
LENNOX-GASTAUT SYNDROME ( 8 patients )
SUICIDE ATTEMPT ( 8 patients )
PETIT MAL EPILEPSY ( 7 patients )
DEPRESSION ( 7 patients )
SIMPLE PARTIAL SEIZURES ( 7 patients )
NERVOUS SYSTEM DISORDER ( 6 patients )
CEREBRAL HAEMORRHAGE ( 6 patients )
ISCHAEMIA ( 6 patients )
POST-TRAUMATIC EPILEPSY ( 5 patients )
NEURALGIA ( 5 patients )
SUBARACHNOID HAEMORRHAGE ( 5 patients )
FOETAL EXPOSURE DURING PREGNANCY ( 5 patients )
PARTIAL SEIZURES WITH SECONDARY GENERALISATION ( 5 patients )
POSTOPERATIVE CARE ( 4 patients )
TRIGEMINAL NEURALGIA ( 4 patients )
TORSADE DE POINTES ( 4 patients )
INJURY ( 4 patients )
BRAIN NEOPLASM ( 4 patients )
HEMIPLEGIA ( 4 patients )
CEREBRAL INFARCTION ( 4 patients )
BRAIN INJURY ( 3 patients )
COMPLETED SUICIDE ( 3 patients )
NEUROPATHY PERIPHERAL ( 3 patients )
SUBDURAL HAEMATOMA ( 3 patients )
SURGERY ( 3 patients )
MUSCLE TWITCHING ( 3 patients )
INTRACRANIAL ANEURYSM ( 3 patients )
ENCEPHALITIS ( 3 patients )
MATERNAL EXPOSURE DURING PREGNANCY ( 3 patients )
MYOTONIA ( 3 patients )
CLONIC CONVULSION ( 2 patients )
HAEMORRHAGE ( 2 patients )
DRUG TOXICITY PROPHYLAXIS ( 2 patients )
HALLUCINATION ( 2 patients )
DYSPHORIA ( 2 patients )
PREMEDICATION ( 2 patients )
CONVULSION NEONATAL ( 2 patients )
FEBRILE CONVULSION ( 2 patients )
ANXIETY ( 2 patients )
MOVEMENT DISORDER ( 2 patients )
ARRHYTHMIA ( 2 patients )
HYPERTENSION ( 2 patients )
DROP ATTACKS ( 2 patients )
MYOCLONUS ( 2 patients )
NEOPLASM MALIGNANT ( 2 patients )
HAEMORRHAGE INTRACRANIAL ( 2 patients )
BRAIN NEOPLASM MALIGNANT ( 2 patients )
ACCIDENTAL EXPOSURE ( 2 patients )
VENTRICULAR TACHYCARDIA ( 2 patients )
ALCOHOLIC SEIZURE ( 2 patients )
SYNCOPE ( 2 patients )
APHASIA ( 2 patients )
DEMENTIA ALZHEIMER'S TYPE ( 2 patients )
HYPERSENSITIVITY ( 2 patients )
MULTIPLE SCLEROSIS ( 2 patients )
THERAPEUTIC AGENT TOXICITY ( 2 patients )
DISEASE RECURRENCE ( 2 patients )
GLIOMA ( 2 patients )
TONIC CLONIC MOVEMENTS ( 2 patients )
MENINGITIS BACTERIAL ( 1 patients )
TRAUMATIC BRAIN INJURY ( 1 patients )
INTENTIONAL OVERDOSE ( 1 patients )
MENINGOENCEPHALITIS BACTERIAL ( 1 patients )
BRAIN NEOPLASM BENIGN ( 1 patients )
INTRACRANIAL INJURY ( 1 patients )
NEUROCYSTICERCOSIS ( 1 patients )
STREPTOCOCCAL INFECTION ( 1 patients )
CONFUSIONAL STATE ( 1 patients )
HEADACHE ( 1 patients )
MENTAL STATUS CHANGES ( 1 patients )
VENTRICULAR ARRHYTHMIA ( 1 patients )
BRAIN TUMOUR OPERATION ( 1 patients )
ENDOMETRIAL CANCER ( 1 patients )
LARGE INTESTINE CARCINOMA ( 1 patients )
ADVERSE DRUG REACTION ( 1 patients )
HIV INFECTION ( 1 patients )
MIGRAINE ( 1 patients )
PROPHYLACTIC CHEMOTHERAPY ( 1 patients )
C-REACTIVE PROTEIN INCREASED ( 1 patients )
LEUKOPENIA ( 1 patients )
OPSOCLONUS MYOCLONUS ( 1 patients )
CRANIOTOMY ( 1 patients )
HYPERLIPIDAEMIA ( 1 patients )
CANCER PAIN ( 1 patients )
MATERNAL DRUGS AFFECTING FOETUS ( 1 patients )
OVERDOSE ( 1 patients )
SYSTEMIC ANTIVIRAL TREATMENT ( 1 patients )
DEPRESSED LEVEL OF CONSCIOUSNESS ( 1 patients )
MUSCLE SPASMS ( 1 patients )
RESTLESSNESS ( 1 patients )
CEREBRAL ARTERY EMBOLISM ( 1 patients )
GASTRITIS ( 1 patients )
MATERNAL EXPOSURE TIMING UNSPECIFIED ( 1 patients )
AUTISM ( 1 patients )
DEVELOPMENTAL DELAY ( 1 patients )
HYPOGLYCAEMIC SEIZURE ( 1 patients )
SARCOIDOSIS ( 1 patients )
THROMBOSIS PROPHYLAXIS ( 1 patients )
BACK PAIN ( 1 patients )
SEIZURE CLUSTER ( 1 patients )
MENINGITIS ( 1 patients )
POST PROCEDURAL COMPLICATION ( 1 patients )
BRAIN ABSCESS ( 1 patients )
DRUG HYPERSENSITIVITY ( 1 patients )
STARING ( 1 patients )
CLOSED HEAD INJURY ( 1 patients )
MENINGITIS STREPTOCOCCAL ( 1 patients )
POSTICTAL STATE ( 1 patients )
TRAUMATIC INTRACRANIAL HAEMORRHAGE ( 1 patients )
STEVENS-JOHNSON SYNDROME ( 1 patients )
MENTAL RETARDATION SEVERITY UNSPECIFIED ( 1 patients )
POSTRESUSCITATION ENCEPHALOPATHY ( 1 patients )
TUBERCULOSIS ( 1 patients )
NEUROPATHIC PAIN ( 1 patients )
BRONCHITIS ( 1 patients )
OEDEMA ( 1 patients )
HYPERKALAEMIA ( 1 patients )
MOUTH INJURY ( 1 patients )
CAECITIS ( 1 patients )
LUNG CANCER METASTATIC ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
RELAXATION THERAPY ( 1 patients )
CENTRAL NERVOUS SYSTEM ABSCESS ( 1 patients )
FRONTOTEMPORAL DEMENTIA ( 1 patients )
PAIN ( 1 patients )
TAENIASIS ( 1 patients )
ATRIAL FIBRILLATION ( 1 patients )
HYPOGLYCAEMIA ( 1 patients )
MUSCLE SPASTICITY ( 1 patients )
ROAD TRAFFIC ACCIDENT ( 1 patients )
CEREBRAL HAEMATOMA ( 1 patients )
GLIOBLASTOMA ( 1 patients )
MEDICATION ERROR ( 1 patients )
B-CELL LYMPHOMA ( 1 patients )
HYPOXIC ENCEPHALOPATHY ( 1 patients )
MYOCLONIC EPILEPSY ( 1 patients )
SCHIZOAFFECTIVE DISORDER ( 1 patients )
MENINGIOMA SURGERY ( 1 patients )
POISONING ( 1 patients )
BIPOLAR I DISORDER ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with ACANTHOLYSIS:

AMBIEN (10 patients)
ABRAXANE (9 patients)
ACIPHEX (9 patients)
AMPICILLIN (9 patients)
ASPIRIN (9 patients)
ATIVAN (9 patients)
AVASTIN (9 patients)
CYMBALTA (9 patients)
LEVOTHYROXINE SODIUM (9 patients)
NORCO (9 patients)
RADIATION (9 patients)
VICODIN (9 patients)
XELODA (9 patients)
ZOLOFT (9 patients)
ZOMETA (9 patients)
ZOFRAN (8 patients)
ARANESP (7 patients)
CAPECITABINE (7 patients)
CEFTRIAXONE (7 patients)
CEPHALEXIN (7 patients)
CIPROFLOXACIN (7 patients)
COLACE (7 patients)
DILAUDID (7 patients)
DOXIL (7 patients)
FEMARA (7 patients)
HYDROCODONE BITARTRATE AND ACETAMINOPHEN (7 patients)
KEFLEX (7 patients)
LASIX (7 patients)
LORAZEPAM (7 patients)
NAPROSYN (7 patients)
NEULASTA (7 patients)
NIACIN (7 patients)
PERCOCET (7 patients)
PROVIGIL (7 patients)
RITALIN (7 patients)
SYNTHROID (7 patients)
TAXOTERE (7 patients)
VANCOMYCIN (7 patients)
VANCOMYCIN HCL (7 patients)
DEXAMETHASONE (6 patients)
FENTANYL (6 patients)
CYCLOSPORINE (4 patients)
PLAVIX (4 patients)
RELAFEN (4 patients)
ACETYLSALICYLIC ACID SRT (3 patients)
ACYCLOVIR (3 patients)
AMITIZA (3 patients)
NABUMETONE (3 patients)
NEXIUM (3 patients)
NIFEDIPINE (3 patients)
XIFAXAN (3 patients)
ALDACTAZIDE (2 patients)
AMLOR (2 patients)
AZATHIOPRINE (2 patients)
CLINDAMYCIN (2 patients)
COZAAR (2 patients)
DEPAKENE (2 patients)
DEPAS (2 patients)
DIGOXIN (2 patients)
DIPYRIDAMOL (2 patients)
EMPYNASE (2 patients)
ENALAPRIL MALEATE (2 patients)
ETRETINATE (2 patients)
FRACTAL (2 patients)
FUCIDIN CREAM (2 patients)
FUROSEMIDE (2 patients)
GAMUNEX (2 patients)
GLUCOR (2 patients)
HALCION (2 patients)
ISOSORBIDE MONONITRATE (2 patients)
LAMICTAL (2 patients)
LAXOBERON (2 patients)
LEVEMIR (2 patients)
MAGLAX (2 patients)
METHYLPREDNISOLONE (2 patients)
MINOCYCLIN (2 patients)
MOPRAL (2 patients)
MORPHINE (2 patients)
NITROGLYCERIN (2 patients)
PREDNISOLONE (2 patients)
PREDNISONE (2 patients)
SECTRAL (2 patients)
STILNOX (2 patients)
THEOPHYLLINE (2 patients)
TOPICAL ANTISEPTICS (2 patients)
ACENOCOUMAROL (1 patients)
ACENOCOUMAROL (ACENOCOUMAROL) (1 patients)
ACTIFED (1 patients)
AMILORIDE (1 patients)
AMILORIDE (AMILORIDE HYDROCHLORIDE) (1 patients)
ARNESP (1 patients)
ATENOLOL (1 patients)
ATORVASTATIN CALCIUM (1 patients)
BEMYLID (1 patients)
BETAMETHASONE DIPROPIIONATE (1 patients)
BETAMETHASONE DIPROPIONATE (1 patients)
CARBAMAZEPINE (1 patients)
CEFIXIME (1 patients)
CILAZAPRIL (1 patients)
CIPROFLOXACIN HCL (1 patients)
CIPROFLOXACIN IV (1 patients)
CISPLATIN (1 patients)
COPEGUS (1 patients)
DEXAMETHASONE ACETATE (1 patients)
DOXIUM (CALCIUM DOBESILATE) (1 patients)
ETHYOL (1 patients)
ETOPOSIDE (1 patients)
FENTANYL-100 (1 patients)
FILGRASTIM (FILGRASTIM) (1 patients)
FINASTERIDE (1 patients)
GEMZAR (1 patients)
GLIBENCLAMIDE (1 patients)
GLIMEPIRIDE (1 patients)
HEMERAN GEL (HEPARINOID) (1 patients)
HUMAN INSULIN (1 patients)
INSULIN ACTRAPID HUMAN (1 patients)
INTRON A (1 patients)
IRINOTECAN HCL (1 patients)
L-THYROXIN (1 patients)
LACIDIPINE (1 patients)
LACIDIPINE (LACIDIPINE) (1 patients)
MAGNESIUM OXIDE (MAGNESIUM OXIDE) (1 patients)
METHOTREXATE (1 patients)
MS CONTIN (1 patients)
OXYCODONE HCL (1 patients)
PEG-INTRON (1 patients)
PHENYTOIN (1 patients)
PRAVASTATIN (1 patients)
PRAVASTATIN SODIUM (1 patients)
PREDNISONE TAB (1 patients)
RADIATION THERAPY (1 patients)
REBETOL (1 patients)
RIBAVIRIN (1 patients)
TAREG (1 patients)
TOPICAL MEDICATIONS (FOR PSORIASIS) (1 patients)
ZETIA (1 patients)
Most common side effects for patients taking PHENYTOIN:
CONVULSION (1297 patients)
DRUG INTERACTION (647 patients)
PYREXIA (384 patients)
DIZZINESS (347 patients)
DRUG INEFFECTIVE (342 patients)
FALL (333 patients)
DRUG TOXICITY (330 patients)
GRAND MAL CONVULSION (296 patients)
VOMITING (286 patients)
NAUSEA (285 patients)
CONFUSIONAL STATE (275 patients)
SOMNOLENCE (265 patients)
RASH (249 patients)
HEADACHE (233 patients)
ASTHENIA (229 patients)
STEVENS-JOHNSON SYNDROME (223 patients)
CONDITION AGGRAVATED (221 patients)
DIARRHOEA (220 patients)
STATUS EPILEPTICUS (214 patients)
BALANCE DISORDER (211 patients)
ATAXIA (209 patients)
SEPSIS (208 patients)
HYPOTENSION (206 patients)
ANTICONVULSANT DRUG LEVEL DECREASED (204 patients)
EPILEPSY (199 patients)
FATIGUE (196 patients)
DYSPNOEA (195 patients)
TOXICITY TO VARIOUS AGENTS (193 patients)
MALAISE (193 patients)
ANTICONVULSANT DRUG LEVEL INCREASED (192 patients)
DRUG RASH WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS (184 patients)
PNEUMONIA (181 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (180 patients)
NYSTAGMUS (177 patients)
LOSS OF CONSCIOUSNESS (176 patients)
COMPLETED SUICIDE (176 patients)
TOXIC EPIDERMAL NECROLYSIS (172 patients)
TREMOR (169 patients)
GAIT DISTURBANCE (168 patients)
PHARMACEUTICAL PRODUCT COMPLAINT (168 patients)
DIPLOPIA (151 patients)
LETHARGY (150 patients)
WEIGHT DECREASED (144 patients)
PAIN (143 patients)
RENAL FAILURE (143 patients)
HYPERTENSION (136 patients)
TACHYCARDIA (134 patients)
VISION BLURRED (134 patients)
DRUG LEVEL DECREASED (133 patients)
DEATH (133 patients)
RESPIRATORY FAILURE (131 patients)
CARDIAC ARREST (130 patients)
DYSARTHRIA (129 patients)
THROMBOCYTOPENIA (126 patients)
COMA (125 patients)
ALANINE AMINOTRANSFERASE INCREASED (125 patients)
DRUG LEVEL INCREASED (124 patients)
COORDINATION ABNORMAL (124 patients)
DEPRESSION (123 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (123 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (122 patients)
MENTAL STATUS CHANGES (117 patients)
OEDEMA PERIPHERAL (117 patients)
ANXIETY (117 patients)
ABDOMINAL PAIN (116 patients)
DYSPHAGIA (116 patients)
ANAEMIA (112 patients)
GASTROINTESTINAL HAEMORRHAGE (111 patients)
RENAL FAILURE ACUTE (110 patients)
HEPATIC FAILURE (107 patients)
OVERDOSE (107 patients)
PLATELET COUNT DECREASED (106 patients)
THERAPEUTIC AGENT TOXICITY (104 patients)
AGITATION (104 patients)
MULTI-ORGAN FAILURE (102 patients)
URINARY TRACT INFECTION (101 patients)
LIVER FUNCTION TEST ABNORMAL (101 patients)
METABOLIC ACIDOSIS (100 patients)
INSOMNIA (100 patients)
DEEP VEIN THROMBOSIS (99 patients)
DRUG HYPERSENSITIVITY (96 patients)
MEMORY IMPAIRMENT (96 patients)
PRURITUS (95 patients)
ENCEPHALOPATHY (95 patients)
FEELING ABNORMAL (95 patients)
NEUTROPENIA (93 patients)
HYPERSENSITIVITY (91 patients)
DECREASED APPETITE (91 patients)
BRAIN OEDEMA (90 patients)
CHEST PAIN (90 patients)
ANOREXIA (90 patients)
APHASIA (90 patients)
DELIRIUM (88 patients)
HAEMOGLOBIN DECREASED (86 patients)
MEDICATION ERROR (85 patients)
SPEECH DISORDER (85 patients)
DISORIENTATION (84 patients)
HYPOGLYCAEMIA (83 patients)
AMNESIA (81 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (81 patients)
LIVER DISORDER (80 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (80 patients)
CEREBROVASCULAR ACCIDENT (80 patients)
HYPOAESTHESIA (79 patients)
HYPONATRAEMIA (78 patients)
ERYTHEMA (77 patients)
INFECTION (76 patients)
DRUG EXPOSURE DURING PREGNANCY (76 patients)
HEPATIC FUNCTION ABNORMAL (75 patients)
PAIN IN EXTREMITY (74 patients)
BRADYCARDIA (73 patients)
TREATMENT NONCOMPLIANCE (73 patients)
BLOOD PRESSURE INCREASED (72 patients)
RASH MACULO-PAPULAR (71 patients)
STOMATITIS (71 patients)
MUSCULAR WEAKNESS (71 patients)
HEPATIC ENZYME INCREASED (71 patients)
AGGRESSION (70 patients)
ATRIAL FIBRILLATION (68 patients)
SYNCOPE (68 patients)
UNRESPONSIVE TO STIMULI (67 patients)
COGNITIVE DISORDER (67 patients)
COAGULOPATHY (66 patients)
RASH GENERALISED (66 patients)
BLOOD ALBUMIN DECREASED (66 patients)
ANTICONVULSANT DRUG LEVEL ABOVE THERAPEUTIC (66 patients)
ANTICONVULSANT DRUG LEVEL BELOW THERAPEUTIC (66 patients)
URTICARIA (65 patients)
EPISTAXIS (65 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (64 patients)
PULMONARY EMBOLISM (63 patients)
DRUG LEVEL BELOW THERAPEUTIC (62 patients)
EOSINOPHILIA (62 patients)
NEUROTOXICITY (62 patients)
PLEURAL EFFUSION (62 patients)
BLOOD BILIRUBIN INCREASED (61 patients)
HEART RATE INCREASED (60 patients)
LYMPHADENOPATHY (60 patients)
WHITE BLOOD CELL COUNT INCREASED (60 patients)
BLOOD PRESSURE DECREASED (60 patients)
MOVEMENT DISORDER (60 patients)
HYPOTONIA (59 patients)
WHITE BLOOD CELL COUNT DECREASED (59 patients)
ERYTHEMA MULTIFORME (59 patients)
BODY TEMPERATURE INCREASED (58 patients)
HYPERHIDROSIS (58 patients)
BACK PAIN (57 patients)
CONSTIPATION (57 patients)
PARAESTHESIA (57 patients)
CEREBELLAR SYNDROME (57 patients)
DEHYDRATION (56 patients)
ACTIVITIES OF DAILY LIVING IMPAIRED (56 patients)
HAEMORRHAGE (56 patients)
RASH ERYTHEMATOUS (55 patients)
URINARY RETENTION (55 patients)
LEUKOPENIA (55 patients)
COUGH (55 patients)
INJURY (54 patients)
SEPTIC SHOCK (54 patients)
DYSKINESIA (54 patients)
HEPATITIS (54 patients)
MYOCARDIAL INFARCTION (54 patients)
DRUG ERUPTION (54 patients)
IDIOSYNCRATIC DRUG REACTION (54 patients)
BLISTER (53 patients)
ACUTE GRAFT VERSUS HOST DISEASE (53 patients)
RHABDOMYOLYSIS (53 patients)
DIABETES MELLITUS (52 patients)
INTERSTITIAL LUNG DISEASE (52 patients)
CONTUSION (52 patients)
FEBRILE NEUTROPENIA (52 patients)
INTENTIONAL OVERDOSE (52 patients)
ABNORMAL BEHAVIOUR (51 patients)
PANCYTOPENIA (51 patients)
PHARYNGEAL OEDEMA (51 patients)
DRUG EFFECT DECREASED (51 patients)
NERVOUS SYSTEM DISORDER (50 patients)
GRAFT VERSUS HOST DISEASE (50 patients)
HALLUCINATION (50 patients)
PETECHIAE (50 patients)
ACUTE HEPATIC FAILURE (49 patients)
SWELLING FACE (49 patients)
RESPIRATORY DISTRESS (49 patients)
VERTIGO (49 patients)
CARDIAC FAILURE CONGESTIVE (48 patients)
WEIGHT INCREASED (48 patients)
CARDIO-RESPIRATORY ARREST (47 patients)
HEPATOTOXICITY (47 patients)
MUCOSAL INFLAMMATION (47 patients)
THERAPEUTIC RESPONSE UNEXPECTED WITH DRUG SUBSTITUTION (47 patients)
CANDIDIASIS (47 patients)
OEDEMA (47 patients)
HAEMODIALYSIS (47 patients)
CEREBRAL ATROPHY (46 patients)
ELECTROENCEPHALOGRAM ABNORMAL (46 patients)
RESPIRATORY ARREST (45 patients)
BLOOD CREATININE INCREASED (45 patients)
SUICIDE ATTEMPT (45 patients)
MUSCLE TWITCHING (44 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (44 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (44 patients)
HYPOALBUMINAEMIA (43 patients)
HEAD INJURY (43 patients)
ARTHRALGIA (43 patients)
ENCEPHALITIS (42 patients)
RENAL IMPAIRMENT (42 patients)
INHIBITORY DRUG INTERACTION (42 patients)
PULMONARY OEDEMA (42 patients)
UPPER RESPIRATORY TRACT INFECTION (42 patients)
HEPATITIS ACUTE (41 patients)

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Recent FactMed Activity for PHENYTOIN


Issue Description / Topic Timestamp
QUESTION
ASTROCYTOMA, LOW GRADE
my wife was operated for astrocytoma grade 2 in Nov 08. at present no medicine but phenytoin level decrised to .5 . now she is taking 400mg apsolin per day.if there will be any relation to cancer. 2015-07-05 09:02:47
QUESTION
dans quelle cas on prend ce produit? 2015-09-06 18:03:40
QUESTION
BRUXISM
Can an 80yo woman develop bruxism w/ taking Dilantin and having diagnosis of hyperthyroidism? 2015-09-19 17:32:52
QUESTION
ECHOLALIA
Can antiepileptic drugs like eslicarbazepine induce catatonia 2015-12-05 14:47:22
QUESTION
HYPERSEXUALITY
Can one of the many patients taking PHENYTOIN XR develope a super HYPERSEXUAL SIDE AFFECTS ,I Have im taking it 60yrs on TEGRETOL XR also did not have a sex disere before i have epilepsy i might have a complication with PHENYTOIN does not feel normal 2016-03-03 22:35:10
QUESTION
DRUG INTERACTION
Any interaction with otc sleeping aids? 2016-06-30 11:23:16
QUESTION
PORPHYRIA
PORPHYRIA and PHENYTOIN relation effect 2016-07-13 23:32:25
QUESTION
HYPOSPADIAS
Drugs causing hypospadias 2016-08-04 14:02:58
QUESTION
BLOOD CREATININE INCREASED
I take phenytoin since 1974 .also tegretol200 now l take zest Riley 20 mg plus dilatrol25 for hypertension like got hyper parathyroid level 238 ugldl doctor give me vita.D and calcium.lrecieved colchicine for gout creatinine is 3.5 cr.clesrance21 .what is your advice please ? 2016-08-08 22:19:01
QUESTION
DYSPHASIA
Have been on Dilantin nearly 45 yrs. Am having dysphagia with liquids and solids. 300 mg HS, inderal 40 mg HS Tylenol #3 prn what can be doing this? No cvas 2016-09-07 18:01:23
QUESTION
PULMONARY FIBROSIS
As a regular phenytoin user for epilepsy and I have since March 2017 been diagnosed with minor pulmonary fibrosis. After a 6 week cruise i have returned with bad coughing, tiredness, and inability to draw a full breath. I have also lost 10lbs in in about 15 days. This is very sudden, before that i was an energetic walker. I am told by my family Doctor, after X-rays that the fibrosis has worsened. Should i stop taking phenytoin and change to another drug? 2018-02-25 11:02:10
QUESTION
DRUG INTERACTION
Can Phenytoin be taken with Betaserc in case of vedtibular vertigo 2018-03-31 03:52:15
QUESTION
LEIOMYOSARCOMA
Hello my sister passed away in 2014 from leomiyosarcoma. She was on 3 per day of phenytonin. We all suspected it was too much. She had meningitis and then seizures, thus the med.has anyone had this happen.thank you. 2018-09-05 22:40:52

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