Is METAPLASIA a side effect of SIMVASTATIN ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of SIMVASTATIN patients who developed METAPLASIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 15 individuals taking SIMVASTATIN reported METAPLASIA to the FDA. A total of 67253 SIMVASTATIN drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between SIMVASTATIN and METAPLASIA. In doing so, we compare SIMVASTATIN with other drugs that cause METAPLASIA, to help you evaluate whether or not SIMVASTATIN causes METAPLASIA. Likewise, this page shows the most highly-reported side effects of SIMVASTATIN, so you can see if METAPLASIA ranks among SIMVASTATIN's most well-known side effects.

Summary Statistics
Reports of SIMVASTATIN causing METAPLASIA: 15
Reports of any side effect of SIMVASTATIN : 67253
Percentage of SIMVASTATIN patients where METAPLASIA is a reported side effect: 0.0223%

FDA reports of any drug causing METAPLASIA : 393
Average percentage for all medicated patients where METAPLASIA is reported as a complication: 0.0025%

Physician opinion on SIMVASTATIN as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing SIMVASTATIN:

BLOOD CHOLESTEROL INCREASED ( 6105 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 5228 patients )
HYPERCHOLESTEROLAEMIA ( 3695 patients )
DRUG USE FOR UNKNOWN INDICATION ( 3035 patients )
HYPERLIPIDAEMIA ( 2769 patients )
BLOOD CHOLESTEROL ( 1813 patients )
DYSLIPIDAEMIA ( 640 patients )
BLOOD CHOLESTEROL ABNORMAL ( 565 patients )
PROPHYLAXIS ( 299 patients )
CORONARY ARTERY DISEASE ( 265 patients )
HYPERTENSION ( 228 patients )
MYOCARDIAL ISCHAEMIA ( 191 patients )
CARDIAC DISORDER ( 161 patients )
ILL-DEFINED DISORDER ( 158 patients )
MYOCARDIAL INFARCTION ( 142 patients )
DIABETES MELLITUS ( 133 patients )
BLOOD TRIGLYCERIDES INCREASED ( 98 patients )
TYPE IIA HYPERLIPIDAEMIA ( 92 patients )
CARDIOVASCULAR EVENT PROPHYLAXIS ( 88 patients )
TRANSIENT ISCHAEMIC ATTACK ( 85 patients )
ARTERIOSCLEROSIS ( 79 patients )
LOW DENSITY LIPOPROTEIN INCREASED ( 72 patients )
TYPE 2 DIABETES MELLITUS ( 69 patients )
LIPIDS INCREASED ( 68 patients )
CEREBROVASCULAR ACCIDENT ( 61 patients )
CARDIOVASCULAR DISORDER ( 56 patients )
ATRIAL FIBRILLATION ( 56 patients )
LIPID METABOLISM DISORDER ( 51 patients )
CEREBROVASCULAR ACCIDENT PROPHYLAXIS ( 47 patients )
HYPERTRIGLYCERIDAEMIA ( 45 patients )
HIGH DENSITY LIPOPROTEIN DECREASED ( 41 patients )
BLOOD CHOLESTEROL DECREASED ( 40 patients )
LIPIDS ( 36 patients )
ACUTE CORONARY SYNDROME ( 36 patients )
ACUTE MYOCARDIAL INFARCTION ( 33 patients )
ISCHAEMIC HEART DISEASE PROPHYLAXIS ( 32 patients )
ANGINA PECTORIS ( 28 patients )
PAIN ( 27 patients )
LIPIDS ABNORMAL ( 24 patients )
ARTERIOSCLEROSIS CORONARY ARTERY ( 23 patients )
BLOOD PRESSURE ( 22 patients )
CARDIAC FAILURE ( 22 patients )
BLOOD TRIGLYCERIDES ( 18 patients )
SUICIDE ATTEMPT ( 17 patients )
METABOLIC DISORDER ( 17 patients )
COMPLETED SUICIDE ( 16 patients )
HEMIPARESIS ( 15 patients )
TYPE V HYPERLIPIDAEMIA ( 14 patients )
CORONARY ARTERY BYPASS ( 13 patients )
TYPE 1 DIABETES MELLITUS ( 13 patients )
THROMBOSIS PROPHYLAXIS ( 13 patients )
METABOLIC SYNDROME ( 11 patients )
BLOOD PRESSURE ABNORMAL ( 11 patients )
HEPATITIS C ( 11 patients )
LOW DENSITY LIPOPROTEIN ( 11 patients )
BLOOD TRIGLYCERIDES ABNORMAL ( 10 patients )
MIXED HYPERLIPIDAEMIA ( 10 patients )
RHABDOMYOLYSIS ( 10 patients )
PROSTATE CANCER ( 9 patients )
BLOOD PRESSURE INCREASED ( 9 patients )
STENT PLACEMENT ( 9 patients )
ANTICOAGULANT THERAPY ( 8 patients )
PRINZMETAL ANGINA ( 7 patients )
HYPERCHLORAEMIA ( 7 patients )
PULMONARY ARTERIAL HYPERTENSION ( 7 patients )
ANGIOPATHY ( 7 patients )
ATHEROSCLEROSIS PROPHYLAXIS ( 6 patients )
CAROTID ARTERY STENOSIS ( 6 patients )
MYALGIA ( 6 patients )
ANAESTHESIA ( 6 patients )
PERIPHERAL VASCULAR DISORDER ( 6 patients )
CARDIAC FAILURE CONGESTIVE ( 6 patients )
RENAL FAILURE CHRONIC ( 6 patients )
ACCIDENTAL EXPOSURE ( 6 patients )
DRESSLER'S SYNDROME ( 6 patients )
VISCERAL ARTERIAL ISCHAEMIA ( 6 patients )
ARRHYTHMIA ( 6 patients )
RENAL DISORDER ( 6 patients )
ARTERIAL DISORDER ( 5 patients )
CEREBRAL ISCHAEMIA ( 5 patients )
CARCINOID SYNDROME ( 5 patients )
MEDICAL DIET ( 5 patients )
CARDIOMYOPATHY ( 5 patients )
LOW DENSITY LIPOPROTEIN DECREASED ( 5 patients )
DIABETES MELLITUS NON-INSULIN-DEPENDENT ( 4 patients )
CHOLESTEROSIS ( 4 patients )
FATIGUE ( 4 patients )
HYPERTONIA ( 4 patients )
HYPOCHOLESTEROLAEMIA ( 4 patients )
POSTOPERATIVE CARE ( 4 patients )
GENERAL PHYSICAL CONDITION ( 4 patients )
BLOOD DISORDER ( 4 patients )
LOW DENSITY LIPOPROTEIN ABNORMAL ( 4 patients )
PULMONARY HYPERTENSION ( 4 patients )
SLEEP DISORDER ( 4 patients )
UNEVALUABLE EVENT ( 4 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 4 patients )
AORTIC OCCLUSION ( 4 patients )
SCHIZOPHRENIA ( 4 patients )
CORONARY ARTERIAL STENT INSERTION ( 4 patients )
ARTERIAL OCCLUSIVE DISEASE ( 4 patients )
LOWER RESPIRATORY TRACT INFECTION ( 4 patients )
LDL/HDL RATIO ( 3 patients )
CHRONIC OBSTRUCTIVE PULMONARY DISEASE ( 3 patients )
OVERDOSE ( 3 patients )
CORONARY ANGIOPLASTY ( 3 patients )
HIGH DENSITY LIPOPROTEIN INCREASED ( 3 patients )
WEIGHT DECREASED ( 3 patients )
CORONARY ARTERY OCCLUSION ( 3 patients )
PERCUTANEOUS CORONARY INTERVENTION ( 3 patients )
CEREBROVASCULAR DISORDER ( 3 patients )
HYPERPROLACTINAEMIA ( 3 patients )
ARTHRALGIA ( 3 patients )
CARDIAC OPERATION ( 3 patients )
DIABETIC DYSLIPIDAEMIA ( 3 patients )
LEFT VENTRICLE OUTFLOW TRACT OBSTRUCTION ( 3 patients )
SUPRAVENTRICULAR TACHYCARDIA ( 3 patients )
OSTEOMYELITIS ( 3 patients )
RHEUMATOID ARTHRITIS ( 3 patients )
BRONCHOPULMONARY ASPERGILLOSIS ( 3 patients )
INFARCTION ( 3 patients )
ALANINE AMINOTRANSFERASE INCREASED ( 3 patients )
CEREBRAL INFARCTION ( 3 patients )
HYPERGLYCAEMIA ( 3 patients )
PERIPHERAL ARTERIAL OCCLUSIVE DISEASE ( 3 patients )
SKIN LESION ( 3 patients )
DEPRESSION ( 3 patients )
FAMILIAL RISK FACTOR ( 3 patients )
ARTHRITIS ( 2 patients )
NEUROMUSCULAR BLOCKADE ( 2 patients )
RENAL IMPAIRMENT ( 2 patients )
ANXIETY ( 2 patients )
LIBIDO INCREASED ( 2 patients )
RETINAL VEIN THROMBOSIS ( 2 patients )
VASCULAR GRAFT ( 2 patients )
AORTIC ARTERIOSCLEROSIS ( 2 patients )
MEMORY IMPAIRMENT ( 2 patients )
ATRIOVENTRICULAR BLOCK ( 2 patients )
OBESITY ( 2 patients )
BLOOD URIC ACID ABNORMAL ( 2 patients )
COMBINED HYPERLIPIDAEMIA ( 2 patients )
HIGH DENSITY LIPOPROTEIN ABNORMAL ( 2 patients )
GOUT ( 2 patients )
INTENTIONAL OVERDOSE ( 2 patients )
PSYCHOTIC DISORDER ( 2 patients )
ENDOSCOPY ( 2 patients )
HYPERLIPASAEMIA ( 2 patients )
SINUSITIS FUNGAL ( 2 patients )
CORONARY REVASCULARISATION ( 2 patients )
LABYRINTHITIS ( 2 patients )
CHEST PAIN ( 2 patients )
NEUROPATHY PERIPHERAL ( 2 patients )
RENAL TRANSPLANT ( 2 patients )
AORTIC ANEURYSM ( 2 patients )
FLUID RETENTION ( 2 patients )
PREMEDICATION ( 2 patients )
BIPOLAR I DISORDER ( 2 patients )
GASTROINTESTINAL DISORDER ( 2 patients )
DRUG THERAPY CHANGED ( 2 patients )
WEIGHT CONTROL ( 2 patients )
GASTROOESOPHAGEAL REFLUX DISEASE ( 2 patients )
PARANOIA ( 2 patients )
MYOSITIS ( 2 patients )
CHEMOTHERAPY ( 2 patients )
PLATELET COUNT ABNORMAL ( 2 patients )
CARDIAC FIBRILLATION ( 1 patients )
URINARY TRACT DISORDER ( 1 patients )
BLOOD THYROID STIMULATING HORMONE INCREASED ( 1 patients )
LUPUS NEPHRITIS ( 1 patients )
POLYCYSTIC OVARIES ( 1 patients )
CARDIAC VALVE DISEASE ( 1 patients )
DIABETIC VASCULAR DISORDER ( 1 patients )
HEPATITIS B ( 1 patients )
NON-SMALL CELL LUNG CANCER ( 1 patients )
FULL BLOOD COUNT ( 1 patients )
SURGERY ( 1 patients )
DIPLOPIA ( 1 patients )
HEPATO-LENTICULAR DEGENERATION ( 1 patients )
RHABDOMYOSARCOMA ( 1 patients )
VERTEBRAL ARTERY OCCLUSION ( 1 patients )
AORTIC VALVE DISEASE ( 1 patients )
GASTRIC DISORDER ( 1 patients )
HYPOTENSION ( 1 patients )
THROMBOSIS ( 1 patients )
ACCIDENTAL OVERDOSE ( 1 patients )
BLOOD CHLORIDE ABNORMAL ( 1 patients )
DRUG THERAPY ( 1 patients )
ROUTINE HEALTH MAINTENANCE ( 1 patients )
WALDENSTROM'S MACROGLOBULINAEMIA ( 1 patients )
APOLIPOPROTEIN ( 1 patients )
BREAKTHROUGH PAIN ( 1 patients )
GASTROINTESTINAL MOTILITY DISORDER ( 1 patients )
THYROIDECTOMY ( 1 patients )
LIPOPROTEIN (A) ABNORMAL ( 1 patients )
PAIN IN EXTREMITY ( 1 patients )
SCLERODERMA ( 1 patients )
C-REACTIVE PROTEIN ABNORMAL ( 1 patients )
INFECTION ( 1 patients )
DYSPNOEA ( 1 patients )
LIVER FUNCTION TEST ABNORMAL ( 1 patients )
PANCYTOPENIA ( 1 patients )
SECONDARY ADRENOCORTICAL INSUFFICIENCY ( 1 patients )
ARTERIAL STENOSIS ( 1 patients )
ANGINA UNSTABLE ( 1 patients )
HEART TRANSPLANT ( 1 patients )
NEOPLASM ( 1 patients )
ANGIOPLASTY ( 1 patients )
ESSENTIAL HYPERTENSION ( 1 patients )
HEART VALVE OPERATION ( 1 patients )
NERVOUS SYSTEM DISORDER ( 1 patients )

Drugs with high FDA adverse event association with METAPLASIA:

ASPIRIN (95 patients)
ZOMETA (90 patients)
AREDIA (78 patients)
FOSAMAX (73 patients)
VIOXX (56 patients)
NEXIUM (50 patients)
VICODIN (44 patients)
MORPHINE (41 patients)
PERCOCET (38 patients)
AMBIEN (38 patients)
FEMARA (38 patients)
LISINOPRIL (37 patients)
TAMOXIFEN CITRATE (37 patients)
LORTAB (36 patients)
OXYCODONE HCL (36 patients)
AMOXICILLIN (34 patients)
VITAMIN D (34 patients)
DECADRON (33 patients)
OMEPRAZOLE (33 patients)
PRILOSEC (33 patients)
OXYCONTIN (32 patients)
LIPITOR (31 patients)
FENTANYL (31 patients)
CYCLOPHOSPHAMIDE (31 patients)
ACCUTANE (29 patients)
FLORINEF (28 patients)
NEURONTIN (28 patients)
HYDROCHLOROTHIAZIDE (27 patients)
AROMASIN (27 patients)
OMNISCAN (27 patients)
COUMADIN (27 patients)
ADRIAMYCIN PFS (26 patients)
EFFEXOR (26 patients)
MIRALAX (26 patients)
IBUPROFEN (26 patients)
TYLENOL-500 (26 patients)
ACETAMINOPHEN (25 patients)
COLACE (25 patients)
PROMETHAZINE (25 patients)
AVELOX (24 patients)
VINCRISTINE (24 patients)
MULTIVITAMIN ^LAPPE^ (23 patients)
SENNA (23 patients)
STERAPRED (23 patients)
CYTOXAN (22 patients)
DEXAMETHASONE (22 patients)
DIGOXIN (22 patients)
FERREX (21 patients)
OSCAL 500-D (21 patients)
DIOVAN (21 patients)
LEVAQUIN (21 patients)
POTASSIUM (21 patients)
CARBOPLATIN (21 patients)
PLAVIX (20 patients)
METOCLOPRAMIDE (20 patients)
PERIOSTAT (20 patients)
GADOLINIUM IN UNSPECIFIED DRUG (20 patients)
CYMBALTA (19 patients)
FAMOTIDINE (19 patients)
OXYCODONE (19 patients)
RADIATION THERAPY (19 patients)
PPD DISPOSABLE (18 patients)
ARIMIDEX (18 patients)
ATENOLOL (18 patients)
URECHOLINE (18 patients)
CEFAZOLIN (18 patients)
PREMARIN (18 patients)
TRAMADOL HCL (17 patients)
FLEXERIL (17 patients)
TOPROL-XL (17 patients)
ATIVAN (17 patients)
ZOFRAN (17 patients)
CALCIUM CHLORIDE (17 patients)
HYDROCODONE BITARTRATE (17 patients)
CIPROFLOXACIN (17 patients)
ALEVE (16 patients)
REVLIMID (16 patients)
PHENERGAN ^AVENTIS PHARMA^ (16 patients)
NAPROSYN (16 patients)
TRAZODONE HCL (16 patients)
XANAX (16 patients)
DULCOLAX (16 patients)
MAGNEVIST (16 patients)
CELEBREX (16 patients)
ZOCOR (16 patients)
LASIX (15 patients)
METHOTREXATE (15 patients)
MS CONTIN (15 patients)
FLUOROURACIL (15 patients)
PREDNISONE (15 patients)
TYLENOL (15 patients)
SIMVASTATIN (15 patients)
GEMZAR (15 patients)
GLUCOPHAGE (15 patients)
DARVOCET-N 100 (15 patients)
THIOTEPA (15 patients)
REMICADE (15 patients)
NIACIN (14 patients)
DILAUDID (14 patients)
ARANESP (14 patients)
FOLIC ACID (14 patients)
DARVOCET-N 50 (14 patients)
ETOPOSIDE (14 patients)
ESTRADERM (14 patients)
BICITRA (14 patients)
PREMPRO (14 patients)
CATAPRES (14 patients)
EFFEXOR XR (13 patients)
ERYTHROMYCIN (13 patients)
BENADRYL (13 patients)
FASLODEX (13 patients)
ULTRAM (13 patients)
FUROSEMIDE (13 patients)
GABAPENTIN (13 patients)
PRINIVIL (13 patients)
VALTREX (13 patients)
MOBIC (13 patients)
TOPAMAX (13 patients)
PERIDEX (12 patients)
REGLAN (12 patients)
ALLOPURINOL (12 patients)
CLONIDINE (12 patients)
NUVARING (12 patients)
FLUDROCORTISONE (12 patients)
[THERAPY UNSPECIFIED] (12 patients)
CEPHALEXIN (12 patients)
PRAVASTATIN (11 patients)
ALBUTEROL (11 patients)
HYDROCODONE (11 patients)
PROZAC (11 patients)
LORAZEPAM (11 patients)
PAXIL (11 patients)
MILK OF MAGNESIA TAB (11 patients)
RED BLOOD CELLS (11 patients)
TOBRADEX (11 patients)
LOVENOX (11 patients)
NITROSTAT (11 patients)
MELPHALAN HYDROCHLORIDE (11 patients)
MESNA (11 patients)
ELAVIL (11 patients)
MACRODANTIN (10 patients)
AMITRIPTYLINE HCL (10 patients)
TORSEMIDE (10 patients)
VELCADE (10 patients)
BACITRACIN (10 patients)
LACTULOSE (10 patients)
LEVOTHYROXINE SODIUM (10 patients)
MENTHOL (10 patients)
PENICILLIN ^GRUNENTHAL^ (10 patients)
CHEMOTHERAPEUTICS (10 patients)
METOPROLOL SUCCINATE (9 patients)
PHENERGAN (9 patients)
SPIRONOLACTONE (9 patients)
AMLODIPINE (9 patients)
OPTIMARK (9 patients)
COREG (9 patients)
PROTONIX (9 patients)
AZATHIOPRINE (9 patients)
LYRICA (9 patients)
MELOXICAM (9 patients)
POTASSIUM CHLORIDE (9 patients)
TAXOTERE (9 patients)
RELAFEN (9 patients)
CALCIUM CARBONATE (9 patients)
HUMIRA (9 patients)
PREVACID (9 patients)
ZANTAC (9 patients)
XELODA (9 patients)
METOPROLOL TARTRATE (9 patients)
CIPRO (9 patients)
ZITHROMAX (9 patients)
RADIOTHERAPY (8 patients)
EPIRUBICIN (8 patients)
ADVAIR DISKUS 100/50 (8 patients)
VIDAZA (8 patients)
ALPRAZOLAM (8 patients)
MEDROL (8 patients)
ASCORBIC ACID (8 patients)
AVANDIA (8 patients)
AVAPRO (8 patients)
VYTORIN (8 patients)
LOVASTATIN (8 patients)
PANTOPRAZOLE (8 patients)
REGRANEX (8 patients)
VASOTEC (8 patients)
PRAVACHOL (8 patients)
FLUDROCORTISONE ACETATE (8 patients)
CALCITRIOL (8 patients)
DECADRON /NET/ (8 patients)
TAXOL (8 patients)
CLIMARA (8 patients)
IFOSFAMIDE + CARBOPLATIN + ETOPOSIDE (8 patients)
TIMOPTIC (8 patients)
PEPCID (8 patients)
EMLA (8 patients)
CIPROFLOXACIN HCL (8 patients)
ZYRTEC (8 patients)
CLARITIN (8 patients)
ACTOS (7 patients)
RANITIDINE (7 patients)
AMOXICILLIN AND CLAVULANATE POTASSIUM (7 patients)
EPOGEN (7 patients)
BACTRIM (7 patients)
KLONOPIN (7 patients)
MULTI-VITAMIN (7 patients)
LIMBITROL (7 patients)
FERROUS SULFATE TAB (7 patients)
ISOSORBIDE DINITRATE (7 patients)
ELIDEL (7 patients)
PERIFUSIN (7 patients)

Most common side effects for patients taking SIMVASTATIN:

DYSPNOEA (4063 patients)
NAUSEA (3934 patients)
DIZZINESS (3462 patients)
PAIN (3212 patients)
FATIGUE (3174 patients)
DRUG INTERACTION (3016 patients)
DIARRHOEA (2942 patients)
ASTHENIA (2771 patients)
FALL (2711 patients)
VOMITING (2638 patients)
DRUG INEFFECTIVE (2491 patients)
RENAL FAILURE ACUTE (2473 patients)
RHABDOMYOLYSIS (2437 patients)
HEADACHE (2394 patients)
MYALGIA (2294 patients)
HYPOTENSION (2135 patients)
CHEST PAIN (2096 patients)
MALAISE (2069 patients)
PAIN IN EXTREMITY (2025 patients)
ANXIETY (2017 patients)
PNEUMONIA (1965 patients)
MYOCARDIAL INFARCTION (1888 patients)
OEDEMA PERIPHERAL (1886 patients)
ANAEMIA (1872 patients)
WEIGHT DECREASED (1843 patients)
ARTHRALGIA (1795 patients)
DEPRESSION (1794 patients)
FLUSHING (1730 patients)
PYREXIA (1710 patients)
RENAL FAILURE (1661 patients)
CONFUSIONAL STATE (1628 patients)
HYPERTENSION (1625 patients)
BACK PAIN (1617 patients)
PRURITUS (1579 patients)
ATRIAL FIBRILLATION (1569 patients)
BLOOD GLUCOSE INCREASED (1553 patients)
INSOMNIA (1509 patients)
CEREBROVASCULAR ACCIDENT (1493 patients)
DEHYDRATION (1475 patients)
COUGH (1387 patients)
GAIT DISTURBANCE (1386 patients)
ABDOMINAL PAIN (1385 patients)
RASH (1368 patients)
MUSCULAR WEAKNESS (1361 patients)
SYNCOPE (1262 patients)
CARDIAC FAILURE CONGESTIVE (1243 patients)
URINARY TRACT INFECTION (1234 patients)
DECREASED APPETITE (1203 patients)
PARAESTHESIA (1174 patients)
HAEMOGLOBIN DECREASED (1164 patients)
FEELING ABNORMAL (1133 patients)
SOMNOLENCE (1110 patients)
BLOOD PRESSURE INCREASED (1100 patients)
LOSS OF CONSCIOUSNESS (1099 patients)
MUSCLE SPASMS (1094 patients)
CONSTIPATION (1092 patients)
ABDOMINAL PAIN UPPER (1088 patients)
DEATH (1078 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (1075 patients)
HYPERHIDROSIS (1070 patients)
BLOOD CREATININE INCREASED (1019 patients)
HYPOAESTHESIA (1002 patients)
WEIGHT INCREASED (985 patients)
SEPSIS (934 patients)
THROMBOCYTOPENIA (918 patients)
CONDITION AGGRAVATED (905 patients)
TREMOR (901 patients)
PLEURAL EFFUSION (888 patients)
GASTROINTESTINAL HAEMORRHAGE (882 patients)
CORONARY ARTERY DISEASE (881 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (872 patients)
ERYTHEMA (858 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (826 patients)
ALANINE AMINOTRANSFERASE INCREASED (815 patients)
INJURY (812 patients)
PALPITATIONS (810 patients)
HYPOGLYCAEMIA (794 patients)
CONVULSION (794 patients)
MEMORY IMPAIRMENT (779 patients)
VISION BLURRED (778 patients)
DIABETES MELLITUS (776 patients)
CARDIAC FAILURE (775 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (757 patients)
DYSPHAGIA (755 patients)
CARDIAC ARREST (746 patients)
AMNESIA (739 patients)
CONTUSION (739 patients)
PULMONARY EMBOLISM (714 patients)
RENAL IMPAIRMENT (707 patients)
LIVER FUNCTION TEST ABNORMAL (695 patients)
DYSPEPSIA (686 patients)
INFECTION (672 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (667 patients)
BLOOD CHOLESTEROL INCREASED (664 patients)
BRADYCARDIA (658 patients)
ACUTE MYOCARDIAL INFARCTION (640 patients)
RESPIRATORY FAILURE (638 patients)
CHILLS (637 patients)
HYPONATRAEMIA (632 patients)
HYPERSENSITIVITY (627 patients)
CHEST DISCOMFORT (626 patients)
FEELING HOT (626 patients)
HEART RATE INCREASED (625 patients)
OSTEOARTHRITIS (617 patients)
TACHYCARDIA (614 patients)
MUSCULOSKELETAL PAIN (610 patients)
HYPERKALAEMIA (609 patients)
PLATELET COUNT DECREASED (609 patients)
OSTEONECROSIS OF JAW (590 patients)
ANGINA PECTORIS (590 patients)
AGITATION (588 patients)
DRY MOUTH (585 patients)
OVERDOSE (584 patients)
BALANCE DISORDER (583 patients)
LETHARGY (574 patients)
CARDIAC DISORDER (569 patients)
DEEP VEIN THROMBOSIS (567 patients)
RECTAL HAEMORRHAGE (564 patients)
HYPOKALAEMIA (562 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (561 patients)
TRANSIENT ISCHAEMIC ATTACK (554 patients)
ABDOMINAL DISCOMFORT (543 patients)
PANCREATITIS (539 patients)
SUICIDAL IDEATION (522 patients)
BRONCHITIS (519 patients)
ARTHRITIS (518 patients)
CELLULITIS (516 patients)
NEUTROPENIA (513 patients)
BLOOD PRESSURE DECREASED (513 patients)
HYPERGLYCAEMIA (500 patients)
HAEMORRHAGE (492 patients)
RENAL FAILURE CHRONIC (491 patients)
ABDOMINAL DISTENSION (488 patients)
EMOTIONAL DISTRESS (487 patients)
HYPERLIPIDAEMIA (487 patients)
URTICARIA (487 patients)
PRODUCT QUALITY ISSUE (486 patients)
VISUAL IMPAIRMENT (485 patients)
PULMONARY OEDEMA (484 patients)
ALOPECIA (481 patients)
HALLUCINATION (477 patients)
EPISTAXIS (473 patients)
ARRHYTHMIA (473 patients)
BLOOD UREA INCREASED (470 patients)
WHITE BLOOD CELL COUNT INCREASED (468 patients)
DYSGEUSIA (461 patients)
JOINT SWELLING (459 patients)
VERTIGO (455 patients)
HEPATIC ENZYME INCREASED (455 patients)
HAEMATURIA (448 patients)
NECK PAIN (447 patients)
NEUROPATHY PERIPHERAL (442 patients)
INJECTION SITE PAIN (437 patients)
BONE DISORDER (435 patients)
ABASIA (434 patients)
SWELLING FACE (434 patients)
MULTI-ORGAN FAILURE (433 patients)
STRESS (430 patients)
SINUSITIS (429 patients)
MOBILITY DECREASED (429 patients)
BLOOD GLUCOSE DECREASED (429 patients)
MITRAL VALVE INCOMPETENCE (428 patients)
HAEMORRHOIDS (427 patients)
MENTAL STATUS CHANGES (426 patients)
ANHEDONIA (425 patients)
CATARACT (425 patients)
SPEECH DISORDER (424 patients)
GASTRITIS (421 patients)
DRUG DOSE OMISSION (417 patients)
ASTHMA (414 patients)
IMPAIRED HEALING (411 patients)
MYOPATHY (410 patients)
DRUG HYPERSENSITIVITY (409 patients)
SWELLING (409 patients)
OFF LABEL USE (408 patients)
CARDIOMEGALY (407 patients)
PANCYTOPENIA (406 patients)
BURNING SENSATION (405 patients)
OEDEMA (402 patients)
MYOSITIS (402 patients)
ANGIOEDEMA (399 patients)
DISORIENTATION (394 patients)
HAEMOPTYSIS (393 patients)
OROPHARYNGEAL PAIN (388 patients)
MUSCULOSKELETAL STIFFNESS (388 patients)
THROMBOSIS (384 patients)
SPINAL OSTEOARTHRITIS (383 patients)
NERVOUSNESS (381 patients)
TYPE 2 DIABETES MELLITUS (370 patients)
NASOPHARYNGITIS (369 patients)
DYSPNOEA EXERTIONAL (368 patients)
INTERVERTEBRAL DISC PROTRUSION (367 patients)
DYSARTHRIA (367 patients)
UNEVALUABLE EVENT (366 patients)
SLEEP DISORDER (365 patients)
INFLUENZA LIKE ILLNESS (363 patients)
ECONOMIC PROBLEM (361 patients)
PAIN IN JAW (359 patients)
INCORRECT DOSE ADMINISTERED (357 patients)
WHITE BLOOD CELL COUNT DECREASED (354 patients)
AGGRESSION (351 patients)
BONE PAIN (348 patients)
NEOPLASM MALIGNANT (345 patients)
DYSURIA (344 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (343 patients)
MYOCARDIAL ISCHAEMIA (343 patients)
CORONARY ARTERY OCCLUSION (342 patients)
ATELECTASIS (341 patients)
CHOLELITHIASIS (340 patients)
HAEMATOCRIT DECREASED (338 patients)

In addition to reviewing our up-to-date FDA research, users may interact with the FactMed community - currently one million members and growing! FactMed online research and discussions are read by patients, scientists, physicians, and other interested health care parties. Post follow up Questions to learn from our diverse readership. Likewise, patients who have experienced unwanted effects are encouraged to share their Concerns to help educate and inform our members.

Recent FactMed Activity for SIMVASTATIN

Issue	Description / Topic	Timestamp
QUESTION RECTAL DISCHARGE	I have a magnolia yellow 'none smelling' rectal discharge. it is an unpleasant waxy chalky paste. I get it most nights. it feels wet, but when I wipe it is more like a chalky paste. I take simvastatin 40's, ranitidine 300 mg morphine sulphate tablets 50mg twice daily. and metformin 800 mg twice daily.	2015-01-10 04:18:34
QUESTION TINNITUS	does the long term use of simvastatin 20mg correlates with tinnitus?	2015-03-24 06:03:18
QUESTION NIPPLE PAIN	I've been taking Simvistatin for 2 months and have noticed right nipple pain and sensitivity. I have also experienced intestinal disorders, nausea and vomiting. Should I get off ths drug and go to something else?	2015-04-01 22:44:54
QUESTION COSTOCHONDRITIS	I have been told by my doctor very recently that i have costocondritis and i have been taking simvastatin 40mg now for 2 months. Im wondering is there a connection and would love to hear if anyone else has had this problem.	2015-04-09 04:21:21
QUESTION DRUG INTERACTION	will simvastatin interact with magsieum	2015-04-25 19:48:15
QUESTION REACTION TO COLOURING	What is the colouring used in simvastatin?	2015-04-29 15:34:14
QUESTION RECURRING SKIN BOILS	Recently my Simvastitan dosage was doubled from 20 to 40 milligrams. Within a couple weeks I started getting reoccurring skin boils. Super super painful, at least two of them a month. Yesterday I had to get 2 of them lacerated to drain them. One was on my right thigh the other one was under my left armpit. I just now read that there is a study going on that Simvastitan can cause skin boils in men around 50 years old. The pain can only be described as a knife stuck in you at all times and when you move it's like they twist the knife. I am wondering if anybody else has this issue or problem ? I'm a very clean person and shower at least once a day and I'm always wearing clean clothes.	2015-04-30 00:07:08
QUESTION LEUKOPLAKIA ORAL	I started using simvastatin for a few months, then I started seeing white patches on both sides of my mouth, below the cheek area closer to the floor of the mouth. I stopped using the medication, and it is still there, sometimes it looks very light in color(white) and sometimes it looks a little more pronounced. Will this go away and can I use certain mouth rinses to help it along	2015-06-11 09:53:11
QUESTION DRUG INTERACTION	Which of these Meds cause highest After effects of Dizziness, Keppra, Taztia, Warfarin, Lisinopril, Simvastatin, Bicalutamide, Lupron	2015-06-15 19:41:25
QUESTION luekplakia	I have the same problem with white patches on both sides of my mouth, cheek area closer to the floor. It looks lighter at times but then the white becomes more noticeable. I have been on simvastatin for 4 months and I have been off of them for 4 months and the white patches are still there. What can I do to treat this problem? Getting pretty annoyed that it is not going away as I thought it would when the drug was discontinued	2015-07-06 20:46:10
QUESTION LEUKOPLAKIA	Used simvastatin and developed luekplakia, will it go away? I have not taken the drug for four months now	2015-07-12 19:41:58
QUESTION DRUG INTERACTION	Does simvastatin have bi carbonate in it. My CO2 LEVELS IS 34.	2015-09-21 20:13:07
QUESTION DRUG INTERACTION	Are there any side effects taking zocor and organic msm	2015-11-23 00:15:47
QUESTION VAGINAL CANDIDIASIS	I have on simvastatin for 3 weeks and have vaginal thrush how can I overcome the problem	2015-12-04 14:57:17
QUESTION SLEEP WALKING	I have been sleep walking and last night pulled a speaker on my head while sleep walking is this a known side effect?	2015-12-06 11:18:20
QUESTION DRUG INTERACTION	can I take my resperadol, Lexapro, simvastatin, fenofibrate together	2015-12-29 23:28:30
QUESTION DRUG INTERACTION	S silver water compatible with climax and simvastin	2016-01-17 16:33:24
QUESTION COSTOCHONDRITIS	I was put on Zocor in August 2015 stopped January 13,2016 stopped taking because of so much pain.Went to Dr.was told I have Costochondritis.Could taking Zocor have cause the pain Im having.I been seeing a Chirorpractor for 5 years.Did great until now.Pain in ribs,breast.and back.	2016-02-19 19:29:54
QUESTION LIPOEDEMA	I have strong reason to suspect I developed lipoedema in my legs as result of taking SIMVASTATIN. I have now stopped taking the drug, and I am wondering how to reverse and cure the lipoedema ?	2016-02-27 08:10:28
CONCERN HOARSENESS	Started Simvastatin February 1 2016, did an antique show in March and completely lost my voice. I also developed Costochondritis in March as well. The only thing that changed was adding the drug Simvastatin. I've stopped and will be seeing my dr on Friday. I also will be seeing if it's done anything to my white count since I have Ideopathic Neutropenia with Leukopenia. Has anyone had their voice come back to normal? Thanks	2016-04-25 22:36:43
QUESTION DRUG INTERACTION	are there any interactions between irbesartan, aspirin simvarstatin salbutamol seretide metformin and gliclazide	2016-05-25 03:04:53
QUESTION DRUG SCREEN FALSE POSITIVE	I have been taking Simvastiatin for about 2 weeks, I get drug tested about that often (UA) and suddenly tested positive for Codeine. The only thing Ive done differently is take Simvastiatin. Does this commonly cause false positives in drug screenings or things such as Codeine? Or if not commonly, has it been at least known to?? And how do i prove my innocence, I have a lot on the line here!	2016-06-21 10:41:06
QUESTION GUILLAIN-BARRE SYNDROME	I came down with Guillain- Barre 8 days after taking Simvastiatin and it was all documented, it triggered a chronic version called CIDP and ended up with a Stem Cell Transplant and now 1.4 million dollars later I get by. I had a lawsuit against Merck but my doctor was threatened with his job if he testified and so it went. I had FDA records and lot of cases reported. rdpfun@earthlink.net if you need to contact me.	2016-12-14 20:46:09
CONCERN GUILLAIN-BARRE SYNDROME	I came down with Guillain- Barre 8 days after taking Simvastiatin and it was all documented, it triggered a chronic version called CIDP and ended up with a Stem Cell Transplant and now 1.4 million dollars later I get by. I had a lawsuit against Merck but my doctor was threatened with his job if he testified and so it went. I had FDA records and lot of cases reported. rdpfun@earthlink.net if you need to contact me.	2016-12-14 20:48:16
QUESTION ABDOMINAL PAIN	What a wofdnreul afternoon treat these would make! I love the addition of thyme. So creative! Thank you for sharing another inspired recipe. I hope you have a wonderful start to your week. Hugs and love from Austin!	2017-03-20 07:10:23

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