Is BLOOD CHOLESTEROL INCREASED a side effect of SORAFENIB (RAF KINASE INHIBITOR) ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of SORAFENIB (RAF KINASE INHIBITOR) patients who developed BLOOD CHOLESTEROL INCREASED.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 1 individuals taking SORAFENIB (RAF KINASE INHIBITOR) reported BLOOD CHOLESTEROL INCREASED to the FDA. A total of 3329 SORAFENIB (RAF KINASE INHIBITOR) drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between SORAFENIB (RAF KINASE INHIBITOR) and BLOOD CHOLESTEROL INCREASED. In doing so, we compare SORAFENIB (RAF KINASE INHIBITOR) with other drugs that cause BLOOD CHOLESTEROL INCREASED, to help you evaluate whether or not SORAFENIB (RAF KINASE INHIBITOR) causes BLOOD CHOLESTEROL INCREASED. Likewise, this page shows the most highly-reported side effects of SORAFENIB (RAF KINASE INHIBITOR), so you can see if BLOOD CHOLESTEROL INCREASED ranks among SORAFENIB (RAF KINASE INHIBITOR)'s most well-known side effects.

Summary Statistics
Reports of SORAFENIB (RAF KINASE INHIBITOR) causing BLOOD CHOLESTEROL INCREASED: 1
Reports of any side effect of SORAFENIB (RAF KINASE INHIBITOR) : 3329
Percentage of SORAFENIB (RAF KINASE INHIBITOR) patients where BLOOD CHOLESTEROL INCREASED is a reported side effect: 0.0300%

FDA reports of any drug causing BLOOD CHOLESTEROL INCREASED : 22446
Average percentage for all medicated patients where BLOOD CHOLESTEROL INCREASED is reported as a complication: 0.1407%

Physician opinion on SORAFENIB (RAF KINASE INHIBITOR) as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing SORAFENIB (RAF KINASE INHIBITOR):

HEPATIC NEOPLASM MALIGNANT ( 770 patients )
RENAL CELL CARCINOMA ( 114 patients )
THYROID CANCER ( 65 patients )
METASTATIC RENAL CELL CARCINOMA ( 44 patients )
THYROID CANCER METASTATIC ( 35 patients )
BREAST CANCER ( 31 patients )
BREAST CANCER METASTATIC ( 27 patients )
GASTRIC CANCER ( 25 patients )
NON-SMALL CELL LUNG CANCER ( 25 patients )
COLORECTAL CANCER METASTATIC ( 22 patients )
RENAL CANCER ( 17 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 14 patients )
BILE DUCT CANCER ( 14 patients )
SALIVARY GLAND CANCER ( 7 patients )
HEPATIC CANCER METASTATIC ( 7 patients )
COLORECTAL CANCER ( 7 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 6 patients )
RECTAL CANCER ( 5 patients )
PANCREATIC CARCINOMA ( 4 patients )
PROSTATE CANCER ( 4 patients )
INTRAOCULAR MELANOMA ( 4 patients )
HEPATIC NEOPLASM MALIGNANT RECURRENT ( 3 patients )
NEOPLASM ( 3 patients )
LIVER DISORDER ( 3 patients )
ANGIOSARCOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 3 patients )
METASTASES TO LUNG ( 3 patients )
HEPATIC NEOPLASM MALIGNANT NON-RESECTABLE ( 3 patients )
COLORECTAL CANCER STAGE IV ( 3 patients )
NEOPLASM MALIGNANT ( 3 patients )
GALLBLADDER CANCER METASTATIC ( 3 patients )
BILIARY CANCER METASTATIC ( 3 patients )
METASTASIS ( 3 patients )
COLON CANCER METASTATIC ( 2 patients )
HYPOPHARYNGEAL CANCER ( 2 patients )
DESMOID TUMOUR ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
ACUTE MYELOID LEUKAEMIA (IN REMISSION) ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
OESOPHAGEAL CARCINOMA ( 2 patients )
METASTATIC MALIGNANT MELANOMA ( 2 patients )
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED ( 2 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 2 patients )
ANGINA PECTORIS ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
OSTEOSARCOMA METASTATIC ( 2 patients )
BONE SARCOMA ( 2 patients )
METASTATIC OCULAR MELANOMA ( 2 patients )
METASTATIC SALIVARY GLAND CANCER ( 2 patients )
TONSIL CANCER ( 2 patients )
MYELODYSPLASTIC SYNDROME ( 1 patients )
PROSTATE CANCER METASTATIC ( 1 patients )
GALLBLADDER CANCER ( 1 patients )
NEUROENDOCRINE TUMOUR ( 1 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 1 patients )
GLIOMA ( 1 patients )
BLADDER CANCER ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
CAROTID ARTERY DISEASE ( 1 patients )
HEPATOBLASTOMA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
ACUTE MYELOID LEUKAEMIA ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
RENAL CANCER METASTATIC ( 1 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 1 patients )
NEUROENDOCRINE CARCINOMA OF THE SKIN ( 1 patients )
MALIGNANT HISTIOCYTOSIS ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 1 patients )
SARCOMA ( 1 patients )
GERM CELL CANCER ( 1 patients )
OESOPHAGEAL ADENOCARCINOMA ( 1 patients )
SQUAMOUS CELL CARCINOMA ( 1 patients )
HEAD AND NECK CANCER ( 1 patients )
OVARIAN EPITHELIAL CANCER ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with BLOOD CHOLESTEROL INCREASED:

SEROQUEL (8815 patients)
FOSAMAX (6753 patients)
VIOXX (5511 patients)
LIPITOR (3447 patients)
ACCUTANE (2954 patients)
ASPIRIN (2212 patients)
ZYPREXA (1968 patients)
CRESTOR (1366 patients)
ZOLOFT (1188 patients)
RISPERDAL (1161 patients)
NEXIUM (1124 patients)
SYNTHROID (1042 patients)
LISINOPRIL (917 patients)
ZOCOR (885 patients)
CELEBREX (883 patients)
XANAX (867 patients)
AVONEX (856 patients)
NEURONTIN (780 patients)
HYDROCHLOROTHIAZIDE (780 patients)
ATENOLOL (777 patients)
PRILOSEC (775 patients)
ABILIFY (755 patients)
PREDNISONE (755 patients)
ALENDRONATE SODIUM (736 patients)
PREMARIN (725 patients)
FOSAMAX PLUS D (706 patients)
PAXIL (698 patients)
AMBIEN (698 patients)
LYRICA (674 patients)
GEODON (673 patients)
SIMVASTATIN (664 patients)
NORVASC (652 patients)
PROZAC (648 patients)
LEXAPRO (647 patients)
LASIX (644 patients)
PLAVIX (626 patients)
CYMBALTA (616 patients)
PREVACID (565 patients)
TOPROL-XL (563 patients)
DEPAKOTE (556 patients)
WELLBUTRIN (554 patients)
HUMIRA (548 patients)
DIOVAN (538 patients)
EFFEXOR (530 patients)
PROTONIX (529 patients)
DURAGESIC-100 (525 patients)
METHOTREXATE (525 patients)
CHANTIX (510 patients)
[THERAPY UNSPECIFIED] (501 patients)
CLONAZEPAM (499 patients)
IBUPROFEN (491 patients)
ALBUTEROL (473 patients)
ZETIA (467 patients)
TRAZODONE HCL (466 patients)
CELEXA (452 patients)
BONIVA (451 patients)
LORAZEPAM (445 patients)
OMEPRAZOLE (442 patients)
CALCIUM (UNSPECIFIED) (438 patients)
HALDOL (433 patients)
METFORMIN HCL (429 patients)
KLONOPIN (423 patients)
ZOMETA (407 patients)
ATIVAN (391 patients)
LEVOTHYROXINE SODIUM (386 patients)
FUROSEMIDE (384 patients)
FOLIC ACID (382 patients)
AVANDIA (382 patients)
VICODIN (379 patients)
ALLEGRA (362 patients)
CLOZARIL (351 patients)
VITAMINS (UNSPECIFIED) (350 patients)
ZYRTEC (348 patients)
ACTONEL (346 patients)
ALPRAZOLAM (344 patients)
BEXTRA (343 patients)
NIASPAN (339 patients)
EFFEXOR XR (337 patients)
COUMADIN (334 patients)
GLUCOPHAGE (333 patients)
SINGULAIR (329 patients)
ADVAIR DISKUS 100/50 (326 patients)
VITAMIN D (317 patients)
DIGOXIN (307 patients)
VIAGRA (305 patients)
ACTOS (300 patients)
PERCOCET (298 patients)
METFORMIN (298 patients)
TRICOR (294 patients)
GABAPENTIN (286 patients)
VALIUM (280 patients)
ENBREL (276 patients)
FLEXERIL (274 patients)
CALCIUM (272 patients)
PRAVACHOL (270 patients)
SPIRIVA (269 patients)
INSULIN (268 patients)
AMNESTEEM (267 patients)
REMICADE (265 patients)
HUMALOG (264 patients)
PREDNISOLONE (263 patients)
NAPROXEN (261 patients)
TOPAMAX (261 patients)
METOPROLOL (259 patients)
ARIMIDEX (256 patients)
POTASSIUM CHLORIDE (255 patients)
LEVOXYL (254 patients)
TYLENOL (CAPLET) (252 patients)
BYETTA (252 patients)
THORAZINE (251 patients)
VITAMIN D (UNSPECIFIED) (250 patients)
LANTUS (249 patients)
VITAMIN E (247 patients)
ZANTAC (245 patients)
MULTI-VITAMINS (244 patients)
ALTACE (242 patients)
ACETAMINOPHEN (241 patients)
FORTEO (240 patients)
LOPRESSOR (239 patients)
FISH OIL (239 patients)
REBIF (238 patients)
TYLENOL (238 patients)
MOTRIN (237 patients)
GLYBURIDE (234 patients)
PREMPRO (234 patients)
DIAZEPAM (233 patients)
ULTRAM (230 patients)
METOPROLOL TARTRATE (230 patients)
REMERON (227 patients)
PROVERA (224 patients)
LORTAB (224 patients)
LITHIUM CARBONATE (223 patients)
COREG (218 patients)
AMOXICILLIN (215 patients)
LAMICTAL (213 patients)
ALLOPURINOL (212 patients)
CLARITIN (212 patients)
ELAVIL (211 patients)
ASCORBIC ACID (210 patients)
LEVAQUIN (208 patients)
COZAAR (208 patients)
CYCLOSPORINE (208 patients)
FLONASE (207 patients)
EVISTA (205 patients)
PREDNISONE TAB (204 patients)
NITROGLYCERIN (204 patients)
CLONIDINE (198 patients)
VYTORIN (198 patients)
ACCUPRIL (196 patients)
AREDIA (193 patients)
AMLODIPINE (192 patients)
BUSPAR (191 patients)
ENALAPRIL MALEATE (188 patients)
OXYCONTIN (188 patients)
TRAZODONE HYDROCHLORIDE (188 patients)
ZITHROMAX (185 patients)
TEMAZEPAM (185 patients)
FEMARA (183 patients)
TOCILIZUMAB (182 patients)
HORMONES (UNSPECIFIED) (181 patients)
ACIPHEX (179 patients)
GLIPIZIDE (179 patients)
ATORVASTATIN CALCIUM (178 patients)
ACETYLSALICYLIC ACID (176 patients)
ZESTRIL (175 patients)
TYSABRI (173 patients)
ACETYLSALICYLIC ACID SRT (169 patients)
SOMA (167 patients)
HYDROCODONE BITARTRATE (166 patients)
AMARYL (165 patients)
BACLOFEN (165 patients)
PRISTIQ (164 patients)
LOVASTATIN (163 patients)
DILANTIN (162 patients)
TEGRETOL (161 patients)
CARDIZEM (161 patients)
PRAVASTATIN (159 patients)
RANITIDINE (158 patients)
FLUOXETINE (157 patients)
LOVAZA (156 patients)
RESTORIL (156 patients)
COLACE (156 patients)
LOTREL (154 patients)
PRINIVIL (154 patients)
HYZAAR (154 patients)
AMITRIPTYLINE HCL (151 patients)
PROMETHAZINE (150 patients)
DARVOCET-N 100 (148 patients)
NUVARING (148 patients)
COMBIVENT (147 patients)
ACTEMRA (146 patients)
SPIRONOLACTONE (145 patients)
SKELAXIN (144 patients)
NASONEX (144 patients)
ADVIL (143 patients)
RISPERIDONE (143 patients)
AMITRIPTYLINE HYDROCHLORIDE (143 patients)
VERAPAMIL (142 patients)
LITHIUM (139 patients)
SEROQUEL XR (139 patients)
REGLAN (139 patients)
ACETAMINOPHEN AND HYDROCODONE BITARTRATE (138 patients)
CEPHALEXIN (138 patients)
VITAMIN B-12 (138 patients)
BENADRYL (137 patients)
WARFARIN SODIUM (137 patients)
TRAZODONE (136 patients)
CALCIUM CARBONATE (134 patients)
CITALOPRAM HYDROBROMIDE (134 patients)
TENORMIN (134 patients)

Most common side effects for patients taking SORAFENIB (RAF KINASE INHIBITOR):

DIARRHOEA (613 patients)
HEPATIC FAILURE (378 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (342 patients)
HEPATIC ENCEPHALOPATHY (320 patients)
FATIGUE (300 patients)
RASH (276 patients)
ASCITES (253 patients)
ABDOMINAL PAIN (237 patients)
DECREASED APPETITE (226 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (198 patients)
PYREXIA (191 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (179 patients)
NAUSEA (165 patients)
HYPERTENSION (160 patients)
ASTHENIA (154 patients)
DEHYDRATION (140 patients)
HEPATIC FUNCTION ABNORMAL (133 patients)
DYSPNOEA (131 patients)
CONFUSIONAL STATE (131 patients)
HYPOKALAEMIA (125 patients)
ALOPECIA (124 patients)
VOMITING (118 patients)
CONSTIPATION (115 patients)
INTERSTITIAL LUNG DISEASE (114 patients)
LEFT VENTRICULAR DYSFUNCTION (113 patients)
DEATH (113 patients)
ENDOCARDITIS (112 patients)
ARTHRALGIA (111 patients)
STOMATITIS (111 patients)
ABDOMINAL PAIN UPPER (110 patients)
JAUNDICE (108 patients)
HEPATIC NEOPLASM MALIGNANT (106 patients)
GASTROINTESTINAL HAEMORRHAGE (106 patients)
RETINAL VASCULAR THROMBOSIS (103 patients)
LOWER GASTROINTESTINAL HAEMORRHAGE (103 patients)
LIVER CARCINOMA RUPTURED (101 patients)
OEDEMA PERIPHERAL (97 patients)
PLEURAL EFFUSION (97 patients)
STAPHYLOCOCCAL INFECTION (96 patients)
PNEUMONIA BACTERIAL (96 patients)
ENTEROBACTER INFECTION (96 patients)
MYOPATHY (95 patients)
DRY MOUTH (94 patients)
PAIN IN EXTREMITY (93 patients)
ANXIETY (90 patients)
MALAISE (89 patients)
PULMONARY EMBOLISM (85 patients)
ANAEMIA (84 patients)
PLATELET COUNT DECREASED (81 patients)
BACK PAIN (79 patients)
SEPSIS (78 patients)
PRURITUS (78 patients)
DUODENAL ULCER (77 patients)
MIGRAINE (76 patients)
MITRAL VALVE INCOMPETENCE (76 patients)
HYPOGLYCAEMIA (76 patients)
C-REACTIVE PROTEIN INCREASED (74 patients)
BLOOD PRESSURE INCREASED (73 patients)
VARICES OESOPHAGEAL (73 patients)
HEADACHE (72 patients)
RETINAL VEIN OCCLUSION (72 patients)
ABASIA (69 patients)
RENAL FAILURE ACUTE (69 patients)
WEIGHT DECREASED (67 patients)
DEEP VEIN THROMBOSIS (67 patients)
DIZZINESS (65 patients)
ERYTHEMA (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (64 patients)
CONVULSION (63 patients)
ALANINE AMINOTRANSFERASE INCREASED (62 patients)
DYSPHONIA (62 patients)
CEREBRAL HAEMORRHAGE (60 patients)
APHAGIA (58 patients)
COLITIS (58 patients)
PNEUMONIA (57 patients)
GASTRIC ULCER (56 patients)
HYPONATRAEMIA (55 patients)
HAEMOGLOBIN DECREASED (53 patients)
RESPIRATORY FAILURE (52 patients)
LUNG DISORDER (52 patients)
CEREBRAL ISCHAEMIA (49 patients)
PARAESTHESIA (49 patients)
BLOOD BILIRUBIN INCREASED (48 patients)
GAIT DISTURBANCE (48 patients)
THYROID CANCER METASTATIC (44 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (43 patients)
PERICARDIAL EFFUSION (41 patients)
THROMBOCYTOPENIA (41 patients)
BLISTER (41 patients)
FEBRILE NEUTROPENIA (40 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (40 patients)
HALLUCINATION (40 patients)
CHILLS (40 patients)
AMMONIA INCREASED (39 patients)
SKIN ULCER (39 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (38 patients)
PAIN (38 patients)
HYPOALBUMINAEMIA (38 patients)
HYPOCALCAEMIA (37 patients)
FALL (37 patients)
POLLAKIURIA (37 patients)
BLOOD PRESSURE DECREASED (37 patients)
SKIN EXFOLIATION (37 patients)
INSOMNIA (36 patients)
CARDIAC ARREST (36 patients)
HYPOAESTHESIA (35 patients)
INFECTIOUS PERITONITIS (35 patients)
MYOCARDIAL INFARCTION (35 patients)
RETINAL VASCULAR DISORDER (34 patients)
RENAL FAILURE (34 patients)
LIPASE INCREASED (34 patients)
HYPERKALAEMIA (33 patients)
HYPERGLYCAEMIA (33 patients)
HAEMOPTYSIS (31 patients)
ATRIAL FIBRILLATION (30 patients)
GENERALISED OEDEMA (30 patients)
FAECAL INCONTINENCE (30 patients)
WHITE BLOOD CELL COUNT DECREASED (30 patients)
CELLULITIS (29 patients)
CHEST PAIN (29 patients)
SOMNOLENCE (29 patients)
HYPERBILIRUBINAEMIA (28 patients)
HYPOTENSION (28 patients)
MUSCLE SPASMS (28 patients)
ABDOMINAL DISTENSION (27 patients)
WHITE BLOOD CELL COUNT INCREASED (27 patients)
VISION BLURRED (27 patients)
HEPATIC PAIN (26 patients)
BLOOD ALBUMIN DECREASED (26 patients)
DYSURIA (25 patients)
RASH GENERALISED (25 patients)
BLOOD SODIUM DECREASED (25 patients)
BLOOD URIC ACID INCREASED (25 patients)
COMA (25 patients)
COUGH (25 patients)
PANCYTOPENIA (25 patients)
ACUTE ABDOMEN (24 patients)
EOSINOPHIL COUNT INCREASED (24 patients)
CEREBROVASCULAR ACCIDENT (24 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (23 patients)
CEREBRAL INFARCTION (23 patients)
HYPOMAGNESAEMIA (23 patients)
RETINAL VEIN THROMBOSIS (23 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (23 patients)
TUMOUR LYSIS SYNDROME (22 patients)
HYPOPHOSPHATAEMIA (22 patients)
INFECTION (22 patients)
ORAL PAIN (22 patients)
BLOOD CREATININE INCREASED (22 patients)
NEUTROPENIA (22 patients)
RENAL IMPAIRMENT (22 patients)
LETHARGY (22 patients)
SKIN TOXICITY (21 patients)
TONGUE BLISTERING (21 patients)
LIVER ABSCESS (21 patients)
HAEMATEMESIS (21 patients)
OESOPHAGEAL VARICES HAEMORRHAGE (20 patients)
MENTAL IMPAIRMENT (20 patients)
NERVOUSNESS (20 patients)
NEPHROTIC SYNDROME (20 patients)
HYPOPHAGIA (20 patients)
ADRENAL INSUFFICIENCY (19 patients)
DRY SKIN (19 patients)
BLOOD AMYLASE INCREASED (19 patients)
OEDEMA (19 patients)
INFECTIOUS PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
COMA HEPATIC (19 patients)
HEART RATE INCREASED (18 patients)
HYPERTENSIVE CRISIS (18 patients)
MYALGIA (18 patients)
ECZEMA (18 patients)
URINARY TRACT INFECTION (18 patients)
NEUROMYOPATHY (18 patients)
MEDICAL DEVICE COMPLICATION (18 patients)
DIVERTICULITIS (18 patients)
OSTEOMYELITIS (18 patients)
CEREBRAL ATROPHY (18 patients)
CEREBRAL VENTRICLE DILATATION (18 patients)
DIABETIC FOOT INFECTION (18 patients)
NECK PAIN (18 patients)
OLIGURIA (17 patients)
GASTROINTESTINAL DISORDER (17 patients)
HAEMATOCHEZIA (17 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (17 patients)
HYPOTHYROIDISM (17 patients)
TRANSAMINASES INCREASED (17 patients)
OROPHARYNGEAL PAIN (17 patients)
CHRONIC MYELOID LEUKAEMIA (17 patients)
NEOPLASM PROGRESSION (17 patients)
METASTASES TO ADRENALS (16 patients)
LYMPHOCYTE COUNT DECREASED (16 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (16 patients)
MULTI-ORGAN FAILURE (16 patients)
FEAR (16 patients)
PANCREATIC CARCINOMA (16 patients)
HYPERSOMNIA (16 patients)
EPILEPSY (16 patients)
SUBARACHNOID HAEMORRHAGE (16 patients)
METASTASES TO LUNG (16 patients)
TACHYCARDIA (16 patients)
MUSCULAR WEAKNESS (16 patients)
KLEBSIELLA SEPSIS (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
DYSGEUSIA (16 patients)
LUNG INFECTION (16 patients)
FAECES DISCOLOURED (16 patients)
PAIN OF SKIN (16 patients)
SPINAL FRACTURE (16 patients)
PANIC REACTION (16 patients)

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