Is FLUSHING a side effect of SORAFENIB (RAF KINASE INHIBITOR) ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of SORAFENIB (RAF KINASE INHIBITOR) patients who developed FLUSHING.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 2 individuals taking SORAFENIB (RAF KINASE INHIBITOR) reported FLUSHING to the FDA. A total of 3329 SORAFENIB (RAF KINASE INHIBITOR) drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between SORAFENIB (RAF KINASE INHIBITOR) and FLUSHING. In doing so, we compare SORAFENIB (RAF KINASE INHIBITOR) with other drugs that cause FLUSHING, to help you evaluate whether or not SORAFENIB (RAF KINASE INHIBITOR) causes FLUSHING. Likewise, this page shows the most highly-reported side effects of SORAFENIB (RAF KINASE INHIBITOR), so you can see if FLUSHING ranks among SORAFENIB (RAF KINASE INHIBITOR)'s most well-known side effects.

Summary Statistics
Reports of SORAFENIB (RAF KINASE INHIBITOR) causing FLUSHING: 2
Reports of any side effect of SORAFENIB (RAF KINASE INHIBITOR) : 3329
Percentage of SORAFENIB (RAF KINASE INHIBITOR) patients where FLUSHING is a reported side effect: 0.0601%

FDA reports of any drug causing FLUSHING : 34663
Average percentage for all medicated patients where FLUSHING is reported as a complication: 0.2172%

Physician opinion on SORAFENIB (RAF KINASE INHIBITOR) as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing SORAFENIB (RAF KINASE INHIBITOR):

HEPATIC NEOPLASM MALIGNANT ( 770 patients )
RENAL CELL CARCINOMA ( 114 patients )
THYROID CANCER ( 65 patients )
METASTATIC RENAL CELL CARCINOMA ( 44 patients )
THYROID CANCER METASTATIC ( 35 patients )
BREAST CANCER ( 31 patients )
BREAST CANCER METASTATIC ( 27 patients )
GASTRIC CANCER ( 25 patients )
NON-SMALL CELL LUNG CANCER ( 25 patients )
COLORECTAL CANCER METASTATIC ( 22 patients )
RENAL CANCER ( 17 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 14 patients )
BILE DUCT CANCER ( 14 patients )
SALIVARY GLAND CANCER ( 7 patients )
HEPATIC CANCER METASTATIC ( 7 patients )
COLORECTAL CANCER ( 7 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 6 patients )
RECTAL CANCER ( 5 patients )
PANCREATIC CARCINOMA ( 4 patients )
PROSTATE CANCER ( 4 patients )
INTRAOCULAR MELANOMA ( 4 patients )
HEPATIC NEOPLASM MALIGNANT RECURRENT ( 3 patients )
NEOPLASM ( 3 patients )
LIVER DISORDER ( 3 patients )
ANGIOSARCOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 3 patients )
METASTASES TO LUNG ( 3 patients )
HEPATIC NEOPLASM MALIGNANT NON-RESECTABLE ( 3 patients )
COLORECTAL CANCER STAGE IV ( 3 patients )
NEOPLASM MALIGNANT ( 3 patients )
GALLBLADDER CANCER METASTATIC ( 3 patients )
BILIARY CANCER METASTATIC ( 3 patients )
METASTASIS ( 3 patients )
COLON CANCER METASTATIC ( 2 patients )
HYPOPHARYNGEAL CANCER ( 2 patients )
DESMOID TUMOUR ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
ACUTE MYELOID LEUKAEMIA (IN REMISSION) ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
OESOPHAGEAL CARCINOMA ( 2 patients )
METASTATIC MALIGNANT MELANOMA ( 2 patients )
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED ( 2 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 2 patients )
ANGINA PECTORIS ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
OSTEOSARCOMA METASTATIC ( 2 patients )
BONE SARCOMA ( 2 patients )
METASTATIC OCULAR MELANOMA ( 2 patients )
METASTATIC SALIVARY GLAND CANCER ( 2 patients )
TONSIL CANCER ( 2 patients )
MYELODYSPLASTIC SYNDROME ( 1 patients )
PROSTATE CANCER METASTATIC ( 1 patients )
GALLBLADDER CANCER ( 1 patients )
NEUROENDOCRINE TUMOUR ( 1 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 1 patients )
GLIOMA ( 1 patients )
BLADDER CANCER ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
CAROTID ARTERY DISEASE ( 1 patients )
HEPATOBLASTOMA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
ACUTE MYELOID LEUKAEMIA ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
RENAL CANCER METASTATIC ( 1 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 1 patients )
NEUROENDOCRINE CARCINOMA OF THE SKIN ( 1 patients )
MALIGNANT HISTIOCYTOSIS ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 1 patients )
SARCOMA ( 1 patients )
GERM CELL CANCER ( 1 patients )
OESOPHAGEAL ADENOCARCINOMA ( 1 patients )
SQUAMOUS CELL CARCINOMA ( 1 patients )
HEAD AND NECK CANCER ( 1 patients )
OVARIAN EPITHELIAL CANCER ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with FLUSHING:

NIASPAN (20887 patients)
ASPIRIN (9994 patients)
SIMCOR (6297 patients)
LISINOPRIL (2500 patients)
REMICADE (2315 patients)
FISH OIL (2167 patients)
CRESTOR (1793 patients)
LIPITOR (1760 patients)
SIMVASTATIN (1730 patients)
SANDOSTATIN LAR (1634 patients)
PLAVIX (1582 patients)
SYNTHROID (1044 patients)
ATENOLOL (1024 patients)
MULTI-VITAMIN (1010 patients)
HYDROCHLOROTHIAZIDE (972 patients)
VITAMIN D (970 patients)
METFORMIN HCL (946 patients)
LOVAZA (938 patients)
METOPROLOL TARTRATE (881 patients)
NEXIUM (848 patients)
OMEPRAZOLE (783 patients)
METOPROLOL (772 patients)
M.V.I. (757 patients)
LEVOTHYROXINE SODIUM (749 patients)
ACETYLSALICYLIC ACID SRT (718 patients)
BENADRYL (691 patients)
DIOVAN (666 patients)
CALCIUM (666 patients)
COUMADIN (661 patients)
HEPARIN SODIUM INJECTION (655 patients)
METFORMIN (639 patients)
FOLIC ACID (632 patients)
TOPROL-XL (626 patients)
PRILOSEC (621 patients)
IBUPROFEN (608 patients)
AMLODIPINE (607 patients)
ZETIA (605 patients)
TYSABRI (581 patients)
VIAGRA (558 patients)
ALLOPURINOL (541 patients)
TRICOR (525 patients)
FUROSEMIDE (513 patients)
ZOCOR (509 patients)
NORVASC (488 patients)
LASIX (476 patients)
ASCORBIC ACID (458 patients)
PREDNISONE (451 patients)
COREG (442 patients)
PRAVASTATIN (419 patients)
XANAX (417 patients)
METHOTREXATE (411 patients)
WARFARIN SODIUM (399 patients)
BENICAR (398 patients)
CARVEDILOL (393 patients)
LEVITRA (388 patients)
POTASSIUM CHLORIDE (384 patients)
HUMIRA (378 patients)
ACTOS (372 patients)
VYTORIN (370 patients)
SINGULAIR (367 patients)
LANTUS (364 patients)
VITAMIN B-12 (358 patients)
PROTONIX (357 patients)
ENBREL (356 patients)
TRILIPIX (355 patients)
RAMIPRIL (348 patients)
HEPARIN SODIUM (347 patients)
FOSAMAX (345 patients)
COATED PDS (344 patients)
PREVACID (342 patients)
DIGOXIN (341 patients)
LEXAPRO (341 patients)
MULTI-VITAMINS (338 patients)
ZOLOFT (333 patients)
COQ10 (332 patients)
ACETAMINOPHEN (329 patients)
GABAPENTIN (324 patients)
CELEBREX (317 patients)
DEXAMETHASONE (316 patients)
GLIPIZIDE (301 patients)
UNKNOWN MEDICATION (300 patients)
ALBUTEROL (294 patients)
FLOMAX (290 patients)
BYETTA (290 patients)
CYMBALTA (289 patients)
AMBIEN (287 patients)
MVT (285 patients)
LORAZEPAM (282 patients)
ZYRTEC (282 patients)
VIT D (282 patients)
FENOFIBRATE (282 patients)
DECADRON (276 patients)
PACLITAXEL (269 patients)
CARBOPLATIN (267 patients)
LYRICA (267 patients)
ADVAIR DISKUS 100/50 (267 patients)
ZANTAC (264 patients)
RANITIDINE (261 patients)
CIALIS (261 patients)
NEURONTIN (259 patients)
ADVICOR (255 patients)
LOVASTATIN (248 patients)
CLONAZEPAM (243 patients)
INSULIN (243 patients)
COZAAR (241 patients)
GLUCOSAMINE (240 patients)
ALLEGRA (237 patients)
VITAMIN E (234 patients)
NITROGLYCERIN (231 patients)
VIOXX (231 patients)
ALTACE (226 patients)
POTASSIUM (225 patients)
AVONEX (225 patients)
SPIRONOLACTONE (225 patients)
TRAZODONE HCL (224 patients)
NEXAVAR (224 patients)
FORTEO (222 patients)
GLUCOPHAGE (222 patients)
WELLBUTRIN (221 patients)
DIOVAN HCT (219 patients)
TRAMADOL HCL (219 patients)
GLYBURIDE (216 patients)
VICODIN (215 patients)
LEVOXYL (214 patients)
EFFEXOR (214 patients)
CLOPIDOGREL (214 patients)
SANDOSTATIN (212 patients)
METOPROLOL SUCCINATE (210 patients)
METFORMIN HYDROCHLORIDE (209 patients)
AVELOX (209 patients)
ATORVASTATIN CALCIUM (208 patients)
SOLU-MEDROL (206 patients)
VITAMIN B COMPLEX CAP (202 patients)
PAXIL (201 patients)
IRON (200 patients)
PREDNISOLONE (199 patients)
ATIVAN (198 patients)
VITAMIN TAB (196 patients)
PREMARIN (195 patients)
CLARITIN (191 patients)
SPIRIVA (188 patients)
BYSTOLIC (187 patients)
BLOOD PRESSURE MEDICATION (184 patients)
LOPRESSOR (182 patients)
SEROQUEL (179 patients)
LEVOTHYROXINE (179 patients)
JANUVIA (177 patients)
ALPRAZOLAM (177 patients)
CLONIDINE (176 patients)
MAGNESIUM (175 patients)
VIT C (174 patients)
WELCHOL (172 patients)
FLUOROURACIL (172 patients)
TAXOTERE (171 patients)
CELEXA (168 patients)
XOLAIR (168 patients)
MICARDIS (167 patients)
HYZAAR (166 patients)
TRACLEER (166 patients)
LOTREL (166 patients)
LOSARTAN POTASSIUM (165 patients)
NIACIN (164 patients)
PROZAC (164 patients)
FLONASE (163 patients)
DILTIAZEM (163 patients)
COPAXONE (163 patients)
ENALAPRIL MALEATE (162 patients)
VERAPAMIL (161 patients)
KLONOPIN (160 patients)
NAPROXEN (160 patients)
TYLENOL (159 patients)
ZOFRAN (158 patients)
PREDNISONE TAB (158 patients)
OXYCONTIN (158 patients)
AVAPRO (157 patients)
TYLENOL (CAPLET) (156 patients)
LANSOPRAZOLE (155 patients)
DOCETAXEL (154 patients)
SYMBICORT (151 patients)
MELOXICAM (150 patients)
ERBITUX (150 patients)
HYDROCORTISONE (149 patients)
TAXOL (149 patients)
VITAMINS (146 patients)
GLIMEPIRIDE (146 patients)
MAGNEVIST (145 patients)
UNKNOWN MEDICATIONS (145 patients)
LISINOPRIL AND HYDROCHLOROTHIAZIDE (145 patients)
CARDIZEM (144 patients)
DIAZEPAM (142 patients)
GEMFIBROZIL (137 patients)
AMITRIPTYLINE HCL (135 patients)
MORPHINE (135 patients)
LAMICTAL (133 patients)
SOLU-CORTEF (133 patients)
ACIPHEX (133 patients)
PERCOCET (132 patients)
CALCIUM ACETATE (132 patients)
IMITREX (129 patients)
PANTOPRAZOLE (129 patients)
FLEXERIL (127 patients)
PRAVACHOL (127 patients)
FLUOXETINE (127 patients)
CITALOPRAM HYDROBROMIDE (126 patients)
JANUMET (123 patients)
BENAZEPRIL HYDROCHLORIDE (122 patients)
TOPAMAX (122 patients)
ATACAND (121 patients)
DEFINITY (121 patients)
LORTAB (121 patients)

Most common side effects for patients taking SORAFENIB (RAF KINASE INHIBITOR):

DIARRHOEA (613 patients)
HEPATIC FAILURE (378 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (342 patients)
HEPATIC ENCEPHALOPATHY (320 patients)
FATIGUE (300 patients)
RASH (276 patients)
ASCITES (253 patients)
ABDOMINAL PAIN (237 patients)
DECREASED APPETITE (226 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (198 patients)
PYREXIA (191 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (179 patients)
NAUSEA (165 patients)
HYPERTENSION (160 patients)
ASTHENIA (154 patients)
DEHYDRATION (140 patients)
HEPATIC FUNCTION ABNORMAL (133 patients)
DYSPNOEA (131 patients)
CONFUSIONAL STATE (131 patients)
HYPOKALAEMIA (125 patients)
ALOPECIA (124 patients)
VOMITING (118 patients)
CONSTIPATION (115 patients)
INTERSTITIAL LUNG DISEASE (114 patients)
LEFT VENTRICULAR DYSFUNCTION (113 patients)
DEATH (113 patients)
ENDOCARDITIS (112 patients)
ARTHRALGIA (111 patients)
STOMATITIS (111 patients)
ABDOMINAL PAIN UPPER (110 patients)
JAUNDICE (108 patients)
HEPATIC NEOPLASM MALIGNANT (106 patients)
GASTROINTESTINAL HAEMORRHAGE (106 patients)
RETINAL VASCULAR THROMBOSIS (103 patients)
LOWER GASTROINTESTINAL HAEMORRHAGE (103 patients)
LIVER CARCINOMA RUPTURED (101 patients)
OEDEMA PERIPHERAL (97 patients)
PLEURAL EFFUSION (97 patients)
STAPHYLOCOCCAL INFECTION (96 patients)
PNEUMONIA BACTERIAL (96 patients)
ENTEROBACTER INFECTION (96 patients)
MYOPATHY (95 patients)
DRY MOUTH (94 patients)
PAIN IN EXTREMITY (93 patients)
ANXIETY (90 patients)
MALAISE (89 patients)
PULMONARY EMBOLISM (85 patients)
ANAEMIA (84 patients)
PLATELET COUNT DECREASED (81 patients)
BACK PAIN (79 patients)
SEPSIS (78 patients)
PRURITUS (78 patients)
DUODENAL ULCER (77 patients)
MIGRAINE (76 patients)
MITRAL VALVE INCOMPETENCE (76 patients)
HYPOGLYCAEMIA (76 patients)
C-REACTIVE PROTEIN INCREASED (74 patients)
BLOOD PRESSURE INCREASED (73 patients)
VARICES OESOPHAGEAL (73 patients)
HEADACHE (72 patients)
RETINAL VEIN OCCLUSION (72 patients)
ABASIA (69 patients)
RENAL FAILURE ACUTE (69 patients)
WEIGHT DECREASED (67 patients)
DEEP VEIN THROMBOSIS (67 patients)
DIZZINESS (65 patients)
ERYTHEMA (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (64 patients)
CONVULSION (63 patients)
ALANINE AMINOTRANSFERASE INCREASED (62 patients)
DYSPHONIA (62 patients)
CEREBRAL HAEMORRHAGE (60 patients)
APHAGIA (58 patients)
COLITIS (58 patients)
PNEUMONIA (57 patients)
GASTRIC ULCER (56 patients)
HYPONATRAEMIA (55 patients)
HAEMOGLOBIN DECREASED (53 patients)
RESPIRATORY FAILURE (52 patients)
LUNG DISORDER (52 patients)
CEREBRAL ISCHAEMIA (49 patients)
PARAESTHESIA (49 patients)
BLOOD BILIRUBIN INCREASED (48 patients)
GAIT DISTURBANCE (48 patients)
THYROID CANCER METASTATIC (44 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (43 patients)
PERICARDIAL EFFUSION (41 patients)
THROMBOCYTOPENIA (41 patients)
BLISTER (41 patients)
FEBRILE NEUTROPENIA (40 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (40 patients)
HALLUCINATION (40 patients)
CHILLS (40 patients)
AMMONIA INCREASED (39 patients)
SKIN ULCER (39 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (38 patients)
PAIN (38 patients)
HYPOALBUMINAEMIA (38 patients)
HYPOCALCAEMIA (37 patients)
FALL (37 patients)
POLLAKIURIA (37 patients)
BLOOD PRESSURE DECREASED (37 patients)
SKIN EXFOLIATION (37 patients)
INSOMNIA (36 patients)
CARDIAC ARREST (36 patients)
HYPOAESTHESIA (35 patients)
INFECTIOUS PERITONITIS (35 patients)
MYOCARDIAL INFARCTION (35 patients)
RETINAL VASCULAR DISORDER (34 patients)
RENAL FAILURE (34 patients)
LIPASE INCREASED (34 patients)
HYPERKALAEMIA (33 patients)
HYPERGLYCAEMIA (33 patients)
HAEMOPTYSIS (31 patients)
ATRIAL FIBRILLATION (30 patients)
GENERALISED OEDEMA (30 patients)
FAECAL INCONTINENCE (30 patients)
WHITE BLOOD CELL COUNT DECREASED (30 patients)
CELLULITIS (29 patients)
CHEST PAIN (29 patients)
SOMNOLENCE (29 patients)
HYPERBILIRUBINAEMIA (28 patients)
HYPOTENSION (28 patients)
MUSCLE SPASMS (28 patients)
ABDOMINAL DISTENSION (27 patients)
WHITE BLOOD CELL COUNT INCREASED (27 patients)
VISION BLURRED (27 patients)
HEPATIC PAIN (26 patients)
BLOOD ALBUMIN DECREASED (26 patients)
DYSURIA (25 patients)
RASH GENERALISED (25 patients)
BLOOD SODIUM DECREASED (25 patients)
BLOOD URIC ACID INCREASED (25 patients)
COMA (25 patients)
COUGH (25 patients)
PANCYTOPENIA (25 patients)
ACUTE ABDOMEN (24 patients)
EOSINOPHIL COUNT INCREASED (24 patients)
CEREBROVASCULAR ACCIDENT (24 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (23 patients)
CEREBRAL INFARCTION (23 patients)
HYPOMAGNESAEMIA (23 patients)
RETINAL VEIN THROMBOSIS (23 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (23 patients)
TUMOUR LYSIS SYNDROME (22 patients)
HYPOPHOSPHATAEMIA (22 patients)
INFECTION (22 patients)
ORAL PAIN (22 patients)
BLOOD CREATININE INCREASED (22 patients)
NEUTROPENIA (22 patients)
RENAL IMPAIRMENT (22 patients)
LETHARGY (22 patients)
SKIN TOXICITY (21 patients)
TONGUE BLISTERING (21 patients)
LIVER ABSCESS (21 patients)
HAEMATEMESIS (21 patients)
OESOPHAGEAL VARICES HAEMORRHAGE (20 patients)
MENTAL IMPAIRMENT (20 patients)
NERVOUSNESS (20 patients)
NEPHROTIC SYNDROME (20 patients)
HYPOPHAGIA (20 patients)
ADRENAL INSUFFICIENCY (19 patients)
DRY SKIN (19 patients)
BLOOD AMYLASE INCREASED (19 patients)
OEDEMA (19 patients)
INFECTIOUS PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
COMA HEPATIC (19 patients)
HEART RATE INCREASED (18 patients)
HYPERTENSIVE CRISIS (18 patients)
MYALGIA (18 patients)
ECZEMA (18 patients)
URINARY TRACT INFECTION (18 patients)
NEUROMYOPATHY (18 patients)
MEDICAL DEVICE COMPLICATION (18 patients)
DIVERTICULITIS (18 patients)
OSTEOMYELITIS (18 patients)
CEREBRAL ATROPHY (18 patients)
CEREBRAL VENTRICLE DILATATION (18 patients)
DIABETIC FOOT INFECTION (18 patients)
NECK PAIN (18 patients)
OLIGURIA (17 patients)
GASTROINTESTINAL DISORDER (17 patients)
HAEMATOCHEZIA (17 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (17 patients)
HYPOTHYROIDISM (17 patients)
TRANSAMINASES INCREASED (17 patients)
OROPHARYNGEAL PAIN (17 patients)
CHRONIC MYELOID LEUKAEMIA (17 patients)
NEOPLASM PROGRESSION (17 patients)
METASTASES TO ADRENALS (16 patients)
LYMPHOCYTE COUNT DECREASED (16 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (16 patients)
MULTI-ORGAN FAILURE (16 patients)
FEAR (16 patients)
PANCREATIC CARCINOMA (16 patients)
HYPERSOMNIA (16 patients)
EPILEPSY (16 patients)
SUBARACHNOID HAEMORRHAGE (16 patients)
METASTASES TO LUNG (16 patients)
TACHYCARDIA (16 patients)
MUSCULAR WEAKNESS (16 patients)
KLEBSIELLA SEPSIS (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
DYSGEUSIA (16 patients)
LUNG INFECTION (16 patients)
FAECES DISCOLOURED (16 patients)
PAIN OF SKIN (16 patients)
SPINAL FRACTURE (16 patients)
PANIC REACTION (16 patients)

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