Study of possible correlation between GASTRITIS and SORAFENIB (RAF KINASE INHIBITOR)
Accompanying discussion about FactMed users Questions and Concerns
About this FactMed analysis covering adverse side effect reports of SORAFENIB (RAF KINASE INHIBITOR) patients who developed GASTRITIS.
FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 1 individuals taking SORAFENIB (RAF KINASE INHIBITOR) reported GASTRITIS to the FDA. A total of 3329 SORAFENIB (RAF KINASE INHIBITOR) drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.FDA Research Report
Introduction This page is designed to help you determine the relationship, if any, between SORAFENIB (RAF KINASE INHIBITOR) and GASTRITIS. In doing so, we compare SORAFENIB (RAF KINASE INHIBITOR) with other drugs that cause GASTRITIS, to help you evaluate whether or not SORAFENIB (RAF KINASE INHIBITOR) causes GASTRITIS. Likewise, this page shows the most highly-reported side effects of SORAFENIB (RAF KINASE INHIBITOR), so you can see if GASTRITIS ranks among SORAFENIB (RAF KINASE INHIBITOR)'s most well-known side effects.
Summary StatisticsReports of SORAFENIB (RAF KINASE INHIBITOR) causing GASTRITIS: 1
Reports of any side effect of SORAFENIB (RAF KINASE INHIBITOR) : 3329
Percentage of SORAFENIB (RAF KINASE INHIBITOR) patients where GASTRITIS is a reported side effect: 0.0300%
FDA reports of any drug causing GASTRITIS : 12783
Average percentage for all medicated patients where GASTRITIS is reported as a complication: 0.0801%
Physician opinion on SORAFENIB (RAF KINASE INHIBITOR) as adverse event culprit:
Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing SORAFENIB (RAF KINASE INHIBITOR):
HEPATIC NEOPLASM MALIGNANT
( 770 patients )RENAL CELL CARCINOMA ( 114 patients )
THYROID CANCER ( 65 patients )
METASTATIC RENAL CELL CARCINOMA ( 44 patients )
THYROID CANCER METASTATIC ( 35 patients )
BREAST CANCER ( 31 patients )
BREAST CANCER METASTATIC ( 27 patients )
GASTRIC CANCER ( 25 patients )
NON-SMALL CELL LUNG CANCER ( 25 patients )
COLORECTAL CANCER METASTATIC ( 22 patients )
RENAL CANCER ( 17 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 14 patients )
BILE DUCT CANCER ( 14 patients )
SALIVARY GLAND CANCER ( 7 patients )
HEPATIC CANCER METASTATIC ( 7 patients )
COLORECTAL CANCER ( 7 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 6 patients )
RECTAL CANCER ( 5 patients )
PANCREATIC CARCINOMA ( 4 patients )
PROSTATE CANCER ( 4 patients )
INTRAOCULAR MELANOMA ( 4 patients )
HEPATIC NEOPLASM MALIGNANT RECURRENT ( 3 patients )
NEOPLASM ( 3 patients )
LIVER DISORDER ( 3 patients )
ANGIOSARCOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 3 patients )
METASTASES TO LUNG ( 3 patients )
HEPATIC NEOPLASM MALIGNANT NON-RESECTABLE ( 3 patients )
COLORECTAL CANCER STAGE IV ( 3 patients )
NEOPLASM MALIGNANT ( 3 patients )
GALLBLADDER CANCER METASTATIC ( 3 patients )
BILIARY CANCER METASTATIC ( 3 patients )
METASTASIS ( 3 patients )
COLON CANCER METASTATIC ( 2 patients )
HYPOPHARYNGEAL CANCER ( 2 patients )
DESMOID TUMOUR ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
ACUTE MYELOID LEUKAEMIA (IN REMISSION) ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
OESOPHAGEAL CARCINOMA ( 2 patients )
METASTATIC MALIGNANT MELANOMA ( 2 patients )
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED ( 2 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 2 patients )
ANGINA PECTORIS ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
OSTEOSARCOMA METASTATIC ( 2 patients )
BONE SARCOMA ( 2 patients )
METASTATIC OCULAR MELANOMA ( 2 patients )
METASTATIC SALIVARY GLAND CANCER ( 2 patients )
TONSIL CANCER ( 2 patients )
MYELODYSPLASTIC SYNDROME ( 1 patients )
PROSTATE CANCER METASTATIC ( 1 patients )
GALLBLADDER CANCER ( 1 patients )
NEUROENDOCRINE TUMOUR ( 1 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 1 patients )
GLIOMA ( 1 patients )
BLADDER CANCER ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
CAROTID ARTERY DISEASE ( 1 patients )
HEPATOBLASTOMA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
ACUTE MYELOID LEUKAEMIA ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
RENAL CANCER METASTATIC ( 1 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 1 patients )
NEUROENDOCRINE CARCINOMA OF THE SKIN ( 1 patients )
MALIGNANT HISTIOCYTOSIS ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 1 patients )
SARCOMA ( 1 patients )
GERM CELL CANCER ( 1 patients )
OESOPHAGEAL ADENOCARCINOMA ( 1 patients )
SQUAMOUS CELL CARCINOMA ( 1 patients )
HEAD AND NECK CANCER ( 1 patients )
OVARIAN EPITHELIAL CANCER ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with GASTRITIS:
VIOXX (3199 patients)
FOSAMAX (3133 patients)
ASPIRIN (1852 patients)
ACCUTANE (1547 patients)
NEXIUM (1124 patients)
ZOMETA (932 patients)
OMEPRAZOLE (762 patients)
LIPITOR (729 patients)
PROTONIX (702 patients)
PRILOSEC (687 patients)
PREDNISONE (672 patients)
LASIX (642 patients)
CELEBREX (635 patients)
COUMADIN (609 patients)
PREVACID (578 patients)
SEROQUEL (571 patients)
LISINOPRIL (564 patients)
PLAVIX (563 patients)
AREDIA (562 patients)
SYNTHROID (536 patients)
AMBIEN (531 patients)
IBUPROFEN (527 patients)
ZOCOR (519 patients)
HEPARIN SODIUM INJECTION (477 patients)
METHOTREXATE (475 patients)
FUROSEMIDE (473 patients)
NORVASC (469 patients)
HUMIRA (464 patients)
NEURONTIN (456 patients)
ZOLOFT (444 patients)
XANAX (440 patients)
VICODIN (437 patients)
ALBUTEROL (424 patients)
SIMVASTATIN (421 patients)
ATENOLOL (411 patients)
LEVAQUIN (404 patients)
HYDROCHLOROTHIAZIDE (403 patients)
FOLIC ACID (400 patients)
ATIVAN (367 patients)
ZOFRAN (349 patients)
DEXAMETHASONE (345 patients)
OXYCONTIN (341 patients)
DIGOXIN (337 patients)
ALENDRONATE SODIUM (333 patients)
TOPROL-XL (331 patients)
PREMARIN (326 patients)
ACETAMINOPHEN (323 patients)
LYRICA (323 patients)
AMOXICILLIN (309 patients)
DIOVAN (306 patients)
PERCOCET (306 patients)
PREDNISOLONE (301 patients)
DURAGESIC-100 (299 patients)
METFORMIN HCL (297 patients)
ZANTAC (296 patients)
CYMBALTA (294 patients)
GABAPENTIN (287 patients)
LORAZEPAM (286 patients)
POTASSIUM CHLORIDE (285 patients)
REGLAN (285 patients)
VITAMIN D (284 patients)
REMICADE (277 patients)
LEVOTHYROXINE SODIUM (276 patients)
DECADRON (266 patients)
YASMIN (265 patients)
LEXAPRO (260 patients)
LORTAB (259 patients)
PAXIL (259 patients)
[THERAPY UNSPECIFIED] (258 patients)
PROZAC (253 patients)
METOCLOPRAMIDE (249 patients)
FOSAMAX PLUS D (248 patients)
PREDNISONE TAB (244 patients)
INSULIN (243 patients)
ALLOPURINOL (238 patients)
FENTANYL (238 patients)
ALLEGRA (237 patients)
NITROGLYCERIN (237 patients)
EFFEXOR (233 patients)
METOPROLOL TARTRATE (230 patients)
FORTEO (229 patients)
VITAMIN E (229 patients)
BONIVA (228 patients)
CELEXA (226 patients)
MORPHINE (222 patients)
SINGULAIR (221 patients)
ACIPHEX (220 patients)
TRAZODONE HCL (218 patients)
CALCIUM CARBONATE (216 patients)
WARFARIN SODIUM (215 patients)
AVONEX (214 patients)
ENBREL (214 patients)
CALCIUM (214 patients)
FLEXERIL (212 patients)
YAZ (212 patients)
LANTUS (212 patients)
NAPROXEN (212 patients)
AMLODIPINE (211 patients)
CLONAZEPAM (211 patients)
PEPCID (209 patients)
BYETTA (208 patients)
ARANESP (205 patients)
COZAAR (205 patients)
MULTI-VITAMINS (202 patients)
CIPRO (202 patients)
VALIUM (201 patients)
WELLBUTRIN (201 patients)
CLONIDINE (200 patients)
FAMOTIDINE (200 patients)
ADVAIR DISKUS 100/50 (198 patients)
RANITIDINE (198 patients)
ALPRAZOLAM (195 patients)
ASCORBIC ACID (194 patients)
ZYRTEC (193 patients)
CIPROFLOXACIN (191 patients)
GLUCOPHAGE (191 patients)
PANTOPRAZOLE (189 patients)
COMPAZINE (189 patients)
COREG (187 patients)
ULTRAM (185 patients)
MULTI-VITAMIN (183 patients)
VINCRISTINE (182 patients)
LOVENOX (182 patients)
ZYPREXA (182 patients)
TYLENOL (181 patients)
ACTONEL (180 patients)
CRESTOR (178 patients)
TYLENOL (CAPLET) (178 patients)
OXYCODONE HCL (177 patients)
THALIDOMIDE (176 patients)
VITAMINS (UNSPECIFIED) (176 patients)
CARBOPLATIN (174 patients)
AUGMENTIN '125' (173 patients)
LANSOPRAZOLE (172 patients)
ADRIAMYCIN PFS (171 patients)
REVLIMID (169 patients)
CYCLOPHOSPHAMIDE (168 patients)
CALCIUM (UNSPECIFIED) (167 patients)
METOPROLOL (166 patients)
BEXTRA (166 patients)
KLONOPIN (166 patients)
PRADAXA (166 patients)
VELCADE (165 patients)
MIRALAX (165 patients)
ACTOS (165 patients)
ELAVIL (164 patients)
TEMAZEPAM (164 patients)
ALTACE (163 patients)
PROMETHAZINE (159 patients)
HEPARIN (159 patients)
PROGRAF (159 patients)
TRAMADOL HCL (158 patients)
TAMOXIFEN CITRATE (157 patients)
FLUOROURACIL (157 patients)
FERROUS SULFATE TAB (156 patients)
MAGNESIUM (156 patients)
ARIMIDEX (154 patients)
METHYLPREDNISOLONE (154 patients)
LOPRESSOR (154 patients)
PRAVACHOL (153 patients)
DILAUDID (153 patients)
BACTRIM (152 patients)
COLACE (150 patients)
SPIRONOLACTONE (150 patients)
FLOMAX (149 patients)
GLIPIZIDE (148 patients)
RAMIPRIL (148 patients)
CLINDAMYCIN (148 patients)
DIAZEPAM (148 patients)
FLONASE (147 patients)
MOTRIN (146 patients)
CYTOXAN (146 patients)
POTASSIUM (145 patients)
BENADRYL (145 patients)
FEMARA (145 patients)
FLUOXETINE (144 patients)
DIFLUCAN (144 patients)
AVANDIA (142 patients)
ZITHROMAX (142 patients)
XELODA (142 patients)
ACYCLOVIR (140 patients)
VOLTAREN (139 patients)
AVELOX (138 patients)
PHENERGAN (138 patients)
NYSTATIN (137 patients)
BACLOFEN (137 patients)
TOPAMAX (135 patients)
AVASTIN (135 patients)
FLAGYL (134 patients)
RIBAVIRIN (133 patients)
SPIRIVA (132 patients)
FLUCONAZOLE (132 patients)
AMITRIPTYLINE HCL (131 patients)
ONDANSETRON (131 patients)
CLARITIN (130 patients)
VITAMIN B-12 (128 patients)
RISPERDAL (128 patients)
NASONEX (126 patients)
HYDROCODONE BITARTRATE (126 patients)
METFORMIN (124 patients)
ENALAPRIL MALEATE (124 patients)
DARVOCET-N 100 (124 patients)
TOCILIZUMAB (122 patients)
MOBIC (122 patients)
KLOR-CON (121 patients)
VITAMIN D (UNSPECIFIED) (121 patients)
ACCUPRIL (120 patients)
SKELAXIN (120 patients)
VANCOMYCIN (120 patients)
SOLU-MEDROL (119 patients)
Most common side effects for patients taking SORAFENIB (RAF KINASE INHIBITOR):
DIARRHOEA (613 patients) HEPATIC FAILURE (378 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (342 patients)
HEPATIC ENCEPHALOPATHY (320 patients)
FATIGUE (300 patients)
RASH (276 patients)
ASCITES (253 patients)
ABDOMINAL PAIN (237 patients)
DECREASED APPETITE (226 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (198 patients)
PYREXIA (191 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (179 patients)
NAUSEA (165 patients)
HYPERTENSION (160 patients)
ASTHENIA (154 patients)
DEHYDRATION (140 patients)
HEPATIC FUNCTION ABNORMAL (133 patients)
DYSPNOEA (131 patients)
CONFUSIONAL STATE (131 patients)
HYPOKALAEMIA (125 patients)
ALOPECIA (124 patients)
VOMITING (118 patients)
CONSTIPATION (115 patients)
INTERSTITIAL LUNG DISEASE (114 patients)
LEFT VENTRICULAR DYSFUNCTION (113 patients)
DEATH (113 patients)
ENDOCARDITIS (112 patients)
ARTHRALGIA (111 patients)
STOMATITIS (111 patients)
ABDOMINAL PAIN UPPER (110 patients)
JAUNDICE (108 patients)
HEPATIC NEOPLASM MALIGNANT (106 patients)
GASTROINTESTINAL HAEMORRHAGE (106 patients)
RETINAL VASCULAR THROMBOSIS (103 patients)
LOWER GASTROINTESTINAL HAEMORRHAGE (103 patients)
LIVER CARCINOMA RUPTURED (101 patients)
OEDEMA PERIPHERAL (97 patients)
PLEURAL EFFUSION (97 patients)
STAPHYLOCOCCAL INFECTION (96 patients)
PNEUMONIA BACTERIAL (96 patients)
ENTEROBACTER INFECTION (96 patients)
MYOPATHY (95 patients)
DRY MOUTH (94 patients)
PAIN IN EXTREMITY (93 patients)
ANXIETY (90 patients)
MALAISE (89 patients)
PULMONARY EMBOLISM (85 patients)
ANAEMIA (84 patients)
PLATELET COUNT DECREASED (81 patients)
BACK PAIN (79 patients)
SEPSIS (78 patients)
PRURITUS (78 patients)
DUODENAL ULCER (77 patients)
MIGRAINE (76 patients)
MITRAL VALVE INCOMPETENCE (76 patients)
HYPOGLYCAEMIA (76 patients)
C-REACTIVE PROTEIN INCREASED (74 patients)
BLOOD PRESSURE INCREASED (73 patients)
VARICES OESOPHAGEAL (73 patients)
HEADACHE (72 patients)
RETINAL VEIN OCCLUSION (72 patients)
ABASIA (69 patients)
RENAL FAILURE ACUTE (69 patients)
WEIGHT DECREASED (67 patients)
DEEP VEIN THROMBOSIS (67 patients)
DIZZINESS (65 patients)
ERYTHEMA (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (64 patients)
CONVULSION (63 patients)
ALANINE AMINOTRANSFERASE INCREASED (62 patients)
DYSPHONIA (62 patients)
CEREBRAL HAEMORRHAGE (60 patients)
APHAGIA (58 patients)
COLITIS (58 patients)
PNEUMONIA (57 patients)
GASTRIC ULCER (56 patients)
HYPONATRAEMIA (55 patients)
HAEMOGLOBIN DECREASED (53 patients)
RESPIRATORY FAILURE (52 patients)
LUNG DISORDER (52 patients)
CEREBRAL ISCHAEMIA (49 patients)
PARAESTHESIA (49 patients)
BLOOD BILIRUBIN INCREASED (48 patients)
GAIT DISTURBANCE (48 patients)
THYROID CANCER METASTATIC (44 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (43 patients)
PERICARDIAL EFFUSION (41 patients)
THROMBOCYTOPENIA (41 patients)
BLISTER (41 patients)
FEBRILE NEUTROPENIA (40 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (40 patients)
HALLUCINATION (40 patients)
CHILLS (40 patients)
AMMONIA INCREASED (39 patients)
SKIN ULCER (39 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (38 patients)
PAIN (38 patients)
HYPOALBUMINAEMIA (38 patients)
HYPOCALCAEMIA (37 patients)
FALL (37 patients)
POLLAKIURIA (37 patients)
BLOOD PRESSURE DECREASED (37 patients)
SKIN EXFOLIATION (37 patients)
INSOMNIA (36 patients)
CARDIAC ARREST (36 patients)
HYPOAESTHESIA (35 patients)
INFECTIOUS PERITONITIS (35 patients)
MYOCARDIAL INFARCTION (35 patients)
RETINAL VASCULAR DISORDER (34 patients)
RENAL FAILURE (34 patients)
LIPASE INCREASED (34 patients)
HYPERKALAEMIA (33 patients)
HYPERGLYCAEMIA (33 patients)
HAEMOPTYSIS (31 patients)
ATRIAL FIBRILLATION (30 patients)
GENERALISED OEDEMA (30 patients)
FAECAL INCONTINENCE (30 patients)
WHITE BLOOD CELL COUNT DECREASED (30 patients)
CELLULITIS (29 patients)
CHEST PAIN (29 patients)
SOMNOLENCE (29 patients)
HYPERBILIRUBINAEMIA (28 patients)
HYPOTENSION (28 patients)
MUSCLE SPASMS (28 patients)
ABDOMINAL DISTENSION (27 patients)
WHITE BLOOD CELL COUNT INCREASED (27 patients)
VISION BLURRED (27 patients)
HEPATIC PAIN (26 patients)
BLOOD ALBUMIN DECREASED (26 patients)
DYSURIA (25 patients)
RASH GENERALISED (25 patients)
BLOOD SODIUM DECREASED (25 patients)
BLOOD URIC ACID INCREASED (25 patients)
COMA (25 patients)
COUGH (25 patients)
PANCYTOPENIA (25 patients)
ACUTE ABDOMEN (24 patients)
EOSINOPHIL COUNT INCREASED (24 patients)
CEREBROVASCULAR ACCIDENT (24 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (23 patients)
CEREBRAL INFARCTION (23 patients)
HYPOMAGNESAEMIA (23 patients)
RETINAL VEIN THROMBOSIS (23 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (23 patients)
TUMOUR LYSIS SYNDROME (22 patients)
HYPOPHOSPHATAEMIA (22 patients)
INFECTION (22 patients)
ORAL PAIN (22 patients)
BLOOD CREATININE INCREASED (22 patients)
NEUTROPENIA (22 patients)
RENAL IMPAIRMENT (22 patients)
LETHARGY (22 patients)
SKIN TOXICITY (21 patients)
TONGUE BLISTERING (21 patients)
LIVER ABSCESS (21 patients)
HAEMATEMESIS (21 patients)
OESOPHAGEAL VARICES HAEMORRHAGE (20 patients)
MENTAL IMPAIRMENT (20 patients)
NERVOUSNESS (20 patients)
NEPHROTIC SYNDROME (20 patients)
HYPOPHAGIA (20 patients)
ADRENAL INSUFFICIENCY (19 patients)
DRY SKIN (19 patients)
BLOOD AMYLASE INCREASED (19 patients)
OEDEMA (19 patients)
INFECTIOUS PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
COMA HEPATIC (19 patients)
HEART RATE INCREASED (18 patients)
HYPERTENSIVE CRISIS (18 patients)
MYALGIA (18 patients)
ECZEMA (18 patients)
URINARY TRACT INFECTION (18 patients)
NEUROMYOPATHY (18 patients)
MEDICAL DEVICE COMPLICATION (18 patients)
DIVERTICULITIS (18 patients)
OSTEOMYELITIS (18 patients)
CEREBRAL ATROPHY (18 patients)
CEREBRAL VENTRICLE DILATATION (18 patients)
DIABETIC FOOT INFECTION (18 patients)
NECK PAIN (18 patients)
OLIGURIA (17 patients)
GASTROINTESTINAL DISORDER (17 patients)
HAEMATOCHEZIA (17 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (17 patients)
HYPOTHYROIDISM (17 patients)
TRANSAMINASES INCREASED (17 patients)
OROPHARYNGEAL PAIN (17 patients)
CHRONIC MYELOID LEUKAEMIA (17 patients)
NEOPLASM PROGRESSION (17 patients)
METASTASES TO ADRENALS (16 patients)
LYMPHOCYTE COUNT DECREASED (16 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (16 patients)
MULTI-ORGAN FAILURE (16 patients)
FEAR (16 patients)
PANCREATIC CARCINOMA (16 patients)
HYPERSOMNIA (16 patients)
EPILEPSY (16 patients)
SUBARACHNOID HAEMORRHAGE (16 patients)
METASTASES TO LUNG (16 patients)
TACHYCARDIA (16 patients)
MUSCULAR WEAKNESS (16 patients)
KLEBSIELLA SEPSIS (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
DYSGEUSIA (16 patients)
LUNG INFECTION (16 patients)
FAECES DISCOLOURED (16 patients)
PAIN OF SKIN (16 patients)
SPINAL FRACTURE (16 patients)
PANIC REACTION (16 patients)
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Recent FactMed Activity for SORAFENIB (RAF KINASE INHIBITOR)
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