Is URTICARIA a side effect of SORAFENIB (RAF KINASE INHIBITOR) ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of SORAFENIB (RAF KINASE INHIBITOR) patients who developed URTICARIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 3 individuals taking SORAFENIB (RAF KINASE INHIBITOR) reported URTICARIA to the FDA. A total of 3329 SORAFENIB (RAF KINASE INHIBITOR) drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between SORAFENIB (RAF KINASE INHIBITOR) and URTICARIA. In doing so, we compare SORAFENIB (RAF KINASE INHIBITOR) with other drugs that cause URTICARIA, to help you evaluate whether or not SORAFENIB (RAF KINASE INHIBITOR) causes URTICARIA. Likewise, this page shows the most highly-reported side effects of SORAFENIB (RAF KINASE INHIBITOR), so you can see if URTICARIA ranks among SORAFENIB (RAF KINASE INHIBITOR)'s most well-known side effects.

Summary Statistics
Reports of SORAFENIB (RAF KINASE INHIBITOR) causing URTICARIA: 3
Reports of any side effect of SORAFENIB (RAF KINASE INHIBITOR) : 3329
Percentage of SORAFENIB (RAF KINASE INHIBITOR) patients where URTICARIA is a reported side effect: 0.0901%

FDA reports of any drug causing URTICARIA : 36582
Average percentage for all medicated patients where URTICARIA is reported as a complication: 0.2293%

Physician opinion on SORAFENIB (RAF KINASE INHIBITOR) as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing SORAFENIB (RAF KINASE INHIBITOR):

HEPATIC NEOPLASM MALIGNANT ( 770 patients )
RENAL CELL CARCINOMA ( 114 patients )
THYROID CANCER ( 65 patients )
METASTATIC RENAL CELL CARCINOMA ( 44 patients )
THYROID CANCER METASTATIC ( 35 patients )
BREAST CANCER ( 31 patients )
BREAST CANCER METASTATIC ( 27 patients )
GASTRIC CANCER ( 25 patients )
NON-SMALL CELL LUNG CANCER ( 25 patients )
COLORECTAL CANCER METASTATIC ( 22 patients )
RENAL CANCER ( 17 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 14 patients )
BILE DUCT CANCER ( 14 patients )
SALIVARY GLAND CANCER ( 7 patients )
HEPATIC CANCER METASTATIC ( 7 patients )
COLORECTAL CANCER ( 7 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 6 patients )
RECTAL CANCER ( 5 patients )
PANCREATIC CARCINOMA ( 4 patients )
PROSTATE CANCER ( 4 patients )
INTRAOCULAR MELANOMA ( 4 patients )
HEPATIC NEOPLASM MALIGNANT RECURRENT ( 3 patients )
NEOPLASM ( 3 patients )
LIVER DISORDER ( 3 patients )
ANGIOSARCOMA ( 3 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 3 patients )
METASTASES TO LUNG ( 3 patients )
HEPATIC NEOPLASM MALIGNANT NON-RESECTABLE ( 3 patients )
COLORECTAL CANCER STAGE IV ( 3 patients )
NEOPLASM MALIGNANT ( 3 patients )
GALLBLADDER CANCER METASTATIC ( 3 patients )
BILIARY CANCER METASTATIC ( 3 patients )
METASTASIS ( 3 patients )
COLON CANCER METASTATIC ( 2 patients )
HYPOPHARYNGEAL CANCER ( 2 patients )
DESMOID TUMOUR ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
ACUTE MYELOID LEUKAEMIA (IN REMISSION) ( 2 patients )
LUNG NEOPLASM MALIGNANT ( 2 patients )
OESOPHAGEAL CARCINOMA ( 2 patients )
METASTATIC MALIGNANT MELANOMA ( 2 patients )
TONGUE NEOPLASM MALIGNANT STAGE UNSPECIFIED ( 2 patients )
METASTATIC SQUAMOUS CELL CARCINOMA ( 2 patients )
ANGINA PECTORIS ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
OSTEOSARCOMA METASTATIC ( 2 patients )
BONE SARCOMA ( 2 patients )
METASTATIC OCULAR MELANOMA ( 2 patients )
METASTATIC SALIVARY GLAND CANCER ( 2 patients )
TONSIL CANCER ( 2 patients )
MYELODYSPLASTIC SYNDROME ( 1 patients )
PROSTATE CANCER METASTATIC ( 1 patients )
GALLBLADDER CANCER ( 1 patients )
NEUROENDOCRINE TUMOUR ( 1 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 1 patients )
GLIOMA ( 1 patients )
BLADDER CANCER ( 1 patients )
OVARIAN CANCER METASTATIC ( 1 patients )
CAROTID ARTERY DISEASE ( 1 patients )
HEPATOBLASTOMA ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
ACUTE MYELOID LEUKAEMIA ( 1 patients )
LUNG ADENOCARCINOMA ( 1 patients )
RENAL CANCER METASTATIC ( 1 patients )
DIFFUSE LARGE B-CELL LYMPHOMA ( 1 patients )
NEUROENDOCRINE CARCINOMA OF THE SKIN ( 1 patients )
MALIGNANT HISTIOCYTOSIS ( 1 patients )
ANTICOAGULANT THERAPY ( 1 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 1 patients )
SARCOMA ( 1 patients )
GERM CELL CANCER ( 1 patients )
OESOPHAGEAL ADENOCARCINOMA ( 1 patients )
SQUAMOUS CELL CARCINOMA ( 1 patients )
HEAD AND NECK CANCER ( 1 patients )
OVARIAN EPITHELIAL CANCER ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with URTICARIA:

REMICADE (1991 patients)
ASPIRIN (1911 patients)
HUMIRA (1642 patients)
FOSAMAX (1264 patients)
TYSABRI (1220 patients)
ENBREL (1216 patients)
MAGNEVIST (1073 patients)
PREDNISONE (939 patients)
BENADRYL (931 patients)
AVELOX (880 patients)
SYNTHROID (841 patients)
ULTRAVIST 300 (814 patients)
METHOTREXATE (806 patients)
LISINOPRIL (797 patients)
LIPITOR (770 patients)
NEXIUM (646 patients)
CHANTIX (640 patients)
ZYRTEC (604 patients)
NIASPAN (593 patients)
CELEBREX (583 patients)
ACETAMINOPHEN (570 patients)
SINGULAIR (560 patients)
OMEPRAZOLE (559 patients)
ALBUTEROL (556 patients)
ATENOLOL (545 patients)
AVONEX (542 patients)
HYDROCHLOROTHIAZIDE (540 patients)
LYRICA (530 patients)
VIOXX (528 patients)
FOLIC ACID (526 patients)
XOLAIR (503 patients)
IBUPROFEN (488 patients)
SIMVASTATIN (487 patients)
ADVAIR DISKUS 100/50 (472 patients)
LEVOTHYROXINE SODIUM (469 patients)
CRESTOR (463 patients)
XANAX (459 patients)
METFORMIN HCL (455 patients)
VITAMIN D (449 patients)
ZOLOFT (442 patients)
LEVAQUIN (441 patients)
ULTRAVIST 150 (434 patients)
PLAVIX (434 patients)
BYETTA (432 patients)
LAMICTAL (423 patients)
LASIX (419 patients)
CYMBALTA (419 patients)
ALEVE (382 patients)
PREDNISONE TAB (378 patients)
SPIRIVA (376 patients)
AMOXICILLIN (370 patients)
LEXAPRO (368 patients)
ULTRAVIST 370 (357 patients)
ALEVE (CAPLET) (355 patients)
PREDNISOLONE (355 patients)
WELLBUTRIN (352 patients)
ALLEGRA (349 patients)
PRILOSEC (348 patients)
NEURONTIN (343 patients)
ULTRAVIST (PHARMACY BULK) (341 patients)
NORVASC (339 patients)
CALCIUM (322 patients)
TOPROL-XL (320 patients)
PREVACID (319 patients)
ZOCOR (317 patients)
PREMARIN (312 patients)
GAMMAGARD LIQUID (310 patients)
LANTUS (309 patients)
AUGMENTIN '125' (309 patients)
DIOVAN (302 patients)
ZOMETA (302 patients)
FUROSEMIDE (299 patients)
AMBIEN (293 patients)
COPAXONE (293 patients)
HEPARIN SODIUM INJECTION (292 patients)
PAXIL (287 patients)
MIRENA (285 patients)
GABAPENTIN (281 patients)
ZANTAC (278 patients)
COUMADIN (275 patients)
FORTEO (270 patients)
PROTONIX (269 patients)
LORAZEPAM (263 patients)
FISH OIL (263 patients)
MULTI-VITAMIN (262 patients)
SEROQUEL (261 patients)
WELLBUTRIN XL (258 patients)
VICODIN (258 patients)
MULTI-VITAMINS (256 patients)
ATIVAN (245 patients)
SOLU-MEDROL (242 patients)
ALLOPURINOL (241 patients)
ALPRAZOLAM (231 patients)
PERCOCET (227 patients)
TYLENOL (CAPLET) (224 patients)
MORPHINE (222 patients)
EFFEXOR (219 patients)
RANITIDINE (218 patients)
ZETIA (216 patients)
TEGRETOL (215 patients)
ZITHROMAX (214 patients)
REVLIMID (213 patients)
AMLODIPINE (212 patients)
CIPROFLOXACIN (209 patients)
EXJADE (208 patients)
CLONAZEPAM (206 patients)
FLONASE (206 patients)
PROZAC (206 patients)
METFORMIN (205 patients)
METOPROLOL TARTRATE (204 patients)
OXYCONTIN (202 patients)
LEVOXYL (201 patients)
VOLTAREN (199 patients)
CLARITIN (197 patients)
ZOFRAN (196 patients)
POTASSIUM CHLORIDE (196 patients)
LANSOPRAZOLE (195 patients)
ASCORBIC ACID (195 patients)
TRAMADOL HCL (192 patients)
SYMBICORT (191 patients)
GLUCOPHAGE (190 patients)
BEXTRA (190 patients)
WARFARIN SODIUM (188 patients)
VITAMIN E (185 patients)
DEXAMETHASONE (183 patients)
TYLENOL (182 patients)
SIMCOR (181 patients)
AREDIA (180 patients)
HYDROXYZINE (180 patients)
MULTIHANCE (178 patients)
INSULIN (178 patients)
KLONOPIN (176 patients)
VENTOLIN (175 patients)
NO CONCURRENT MEDICATION (175 patients)
FLUOROURACIL (175 patients)
DECADRON (174 patients)
ATARAX (174 patients)
ACTONEL (173 patients)
JANUVIA (170 patients)
LORATADINE (169 patients)
REBIF (169 patients)
OXYCODONE HCL (168 patients)
ACCUTANE (167 patients)
TRAZODONE HCL (165 patients)
DIGOXIN (165 patients)
ADVIL (164 patients)
CIMZIA (163 patients)
EFFEXOR XR (163 patients)
NAPROXEN (162 patients)
GLEEVEC (162 patients)
TOPAMAX (160 patients)
COZAAR (160 patients)
CELEXA (159 patients)
VITAMIN B-12 (159 patients)
METOPROLOL (157 patients)
CLONIDINE (157 patients)
DURAGESIC-100 (156 patients)
BACTRIM (156 patients)
FENTANYL (154 patients)
ALENDRONATE SODIUM (153 patients)
DEFINITY (153 patients)
BENICAR (149 patients)
HUMALOG (149 patients)
FLOMAX (149 patients)
CALCIUM CARBONATE (146 patients)
ACETYLSALICYLIC ACID SRT (146 patients)
ZYBAN (145 patients)
VALTREX (145 patients)
ERBITUX (144 patients)
VICTOZA (144 patients)
TRICOR (142 patients)
RAMIPRIL (141 patients)
NASONEX (141 patients)
DIAZEPAM (141 patients)
BONIVA (140 patients)
ALTACE (140 patients)
PRADAXA (139 patients)
NEULASTA (139 patients)
VALIUM (139 patients)
VANCOMYCIN (138 patients)
ROCEPHIN (138 patients)
LOVENOX (138 patients)
COREG (137 patients)
LORTAB (137 patients)
GLIPIZIDE (136 patients)
GADAVIST (136 patients)
LAMISIL (136 patients)
CARBOPLATIN (136 patients)
PEGASYS (135 patients)
FAMOTIDINE (134 patients)
MOBIC (134 patients)
AZITHROMYCIN (134 patients)
CYCLOPHOSPHAMIDE (134 patients)
HYDROCORTISONE (132 patients)
PRAVASTATIN (131 patients)
PARACETAMOL (131 patients)
BETASERON (131 patients)
PLAQUENIL (130 patients)
AVANDIA (130 patients)
RIBAVIRIN (130 patients)
FLOVENT (129 patients)
ALLI (127 patients)
FLUOXETINE (126 patients)
ENALAPRIL MALEATE (125 patients)
CETIRIZINE HCL (123 patients)
ACYCLOVIR (123 patients)
FOSAMAX PLUS D (122 patients)
MEDROL (122 patients)
OPTIRAY 350 (122 patients)
DIPHENHYDRAMINE HCL (121 patients)

Most common side effects for patients taking SORAFENIB (RAF KINASE INHIBITOR):

DIARRHOEA (613 patients)
HEPATIC FAILURE (378 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (342 patients)
HEPATIC ENCEPHALOPATHY (320 patients)
FATIGUE (300 patients)
RASH (276 patients)
ASCITES (253 patients)
ABDOMINAL PAIN (237 patients)
DECREASED APPETITE (226 patients)
UPPER GASTROINTESTINAL HAEMORRHAGE (198 patients)
PYREXIA (191 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (179 patients)
NAUSEA (165 patients)
HYPERTENSION (160 patients)
ASTHENIA (154 patients)
DEHYDRATION (140 patients)
HEPATIC FUNCTION ABNORMAL (133 patients)
DYSPNOEA (131 patients)
CONFUSIONAL STATE (131 patients)
HYPOKALAEMIA (125 patients)
ALOPECIA (124 patients)
VOMITING (118 patients)
CONSTIPATION (115 patients)
INTERSTITIAL LUNG DISEASE (114 patients)
LEFT VENTRICULAR DYSFUNCTION (113 patients)
DEATH (113 patients)
ENDOCARDITIS (112 patients)
ARTHRALGIA (111 patients)
STOMATITIS (111 patients)
ABDOMINAL PAIN UPPER (110 patients)
JAUNDICE (108 patients)
HEPATIC NEOPLASM MALIGNANT (106 patients)
GASTROINTESTINAL HAEMORRHAGE (106 patients)
RETINAL VASCULAR THROMBOSIS (103 patients)
LOWER GASTROINTESTINAL HAEMORRHAGE (103 patients)
LIVER CARCINOMA RUPTURED (101 patients)
OEDEMA PERIPHERAL (97 patients)
PLEURAL EFFUSION (97 patients)
STAPHYLOCOCCAL INFECTION (96 patients)
PNEUMONIA BACTERIAL (96 patients)
ENTEROBACTER INFECTION (96 patients)
MYOPATHY (95 patients)
DRY MOUTH (94 patients)
PAIN IN EXTREMITY (93 patients)
ANXIETY (90 patients)
MALAISE (89 patients)
PULMONARY EMBOLISM (85 patients)
ANAEMIA (84 patients)
PLATELET COUNT DECREASED (81 patients)
BACK PAIN (79 patients)
SEPSIS (78 patients)
PRURITUS (78 patients)
DUODENAL ULCER (77 patients)
MIGRAINE (76 patients)
MITRAL VALVE INCOMPETENCE (76 patients)
HYPOGLYCAEMIA (76 patients)
C-REACTIVE PROTEIN INCREASED (74 patients)
BLOOD PRESSURE INCREASED (73 patients)
VARICES OESOPHAGEAL (73 patients)
HEADACHE (72 patients)
RETINAL VEIN OCCLUSION (72 patients)
ABASIA (69 patients)
RENAL FAILURE ACUTE (69 patients)
WEIGHT DECREASED (67 patients)
DEEP VEIN THROMBOSIS (67 patients)
DIZZINESS (65 patients)
ERYTHEMA (65 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (64 patients)
CONVULSION (63 patients)
ALANINE AMINOTRANSFERASE INCREASED (62 patients)
DYSPHONIA (62 patients)
CEREBRAL HAEMORRHAGE (60 patients)
APHAGIA (58 patients)
COLITIS (58 patients)
PNEUMONIA (57 patients)
GASTRIC ULCER (56 patients)
HYPONATRAEMIA (55 patients)
HAEMOGLOBIN DECREASED (53 patients)
RESPIRATORY FAILURE (52 patients)
LUNG DISORDER (52 patients)
CEREBRAL ISCHAEMIA (49 patients)
PARAESTHESIA (49 patients)
BLOOD BILIRUBIN INCREASED (48 patients)
GAIT DISTURBANCE (48 patients)
THYROID CANCER METASTATIC (44 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (43 patients)
PERICARDIAL EFFUSION (41 patients)
THROMBOCYTOPENIA (41 patients)
BLISTER (41 patients)
FEBRILE NEUTROPENIA (40 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (40 patients)
HALLUCINATION (40 patients)
CHILLS (40 patients)
AMMONIA INCREASED (39 patients)
SKIN ULCER (39 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (38 patients)
PAIN (38 patients)
HYPOALBUMINAEMIA (38 patients)
HYPOCALCAEMIA (37 patients)
FALL (37 patients)
POLLAKIURIA (37 patients)
BLOOD PRESSURE DECREASED (37 patients)
SKIN EXFOLIATION (37 patients)
INSOMNIA (36 patients)
CARDIAC ARREST (36 patients)
HYPOAESTHESIA (35 patients)
INFECTIOUS PERITONITIS (35 patients)
MYOCARDIAL INFARCTION (35 patients)
RETINAL VASCULAR DISORDER (34 patients)
RENAL FAILURE (34 patients)
LIPASE INCREASED (34 patients)
HYPERKALAEMIA (33 patients)
HYPERGLYCAEMIA (33 patients)
HAEMOPTYSIS (31 patients)
ATRIAL FIBRILLATION (30 patients)
GENERALISED OEDEMA (30 patients)
FAECAL INCONTINENCE (30 patients)
WHITE BLOOD CELL COUNT DECREASED (30 patients)
CELLULITIS (29 patients)
CHEST PAIN (29 patients)
SOMNOLENCE (29 patients)
HYPERBILIRUBINAEMIA (28 patients)
HYPOTENSION (28 patients)
MUSCLE SPASMS (28 patients)
ABDOMINAL DISTENSION (27 patients)
WHITE BLOOD CELL COUNT INCREASED (27 patients)
VISION BLURRED (27 patients)
HEPATIC PAIN (26 patients)
BLOOD ALBUMIN DECREASED (26 patients)
DYSURIA (25 patients)
RASH GENERALISED (25 patients)
BLOOD SODIUM DECREASED (25 patients)
BLOOD URIC ACID INCREASED (25 patients)
COMA (25 patients)
COUGH (25 patients)
PANCYTOPENIA (25 patients)
ACUTE ABDOMEN (24 patients)
EOSINOPHIL COUNT INCREASED (24 patients)
CEREBROVASCULAR ACCIDENT (24 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (23 patients)
CEREBRAL INFARCTION (23 patients)
HYPOMAGNESAEMIA (23 patients)
RETINAL VEIN THROMBOSIS (23 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (23 patients)
TUMOUR LYSIS SYNDROME (22 patients)
HYPOPHOSPHATAEMIA (22 patients)
INFECTION (22 patients)
ORAL PAIN (22 patients)
BLOOD CREATININE INCREASED (22 patients)
NEUTROPENIA (22 patients)
RENAL IMPAIRMENT (22 patients)
LETHARGY (22 patients)
SKIN TOXICITY (21 patients)
TONGUE BLISTERING (21 patients)
LIVER ABSCESS (21 patients)
HAEMATEMESIS (21 patients)
OESOPHAGEAL VARICES HAEMORRHAGE (20 patients)
MENTAL IMPAIRMENT (20 patients)
NERVOUSNESS (20 patients)
NEPHROTIC SYNDROME (20 patients)
HYPOPHAGIA (20 patients)
ADRENAL INSUFFICIENCY (19 patients)
DRY SKIN (19 patients)
BLOOD AMYLASE INCREASED (19 patients)
OEDEMA (19 patients)
INFECTIOUS PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
COMA HEPATIC (19 patients)
HEART RATE INCREASED (18 patients)
HYPERTENSIVE CRISIS (18 patients)
MYALGIA (18 patients)
ECZEMA (18 patients)
URINARY TRACT INFECTION (18 patients)
NEUROMYOPATHY (18 patients)
MEDICAL DEVICE COMPLICATION (18 patients)
DIVERTICULITIS (18 patients)
OSTEOMYELITIS (18 patients)
CEREBRAL ATROPHY (18 patients)
CEREBRAL VENTRICLE DILATATION (18 patients)
DIABETIC FOOT INFECTION (18 patients)
NECK PAIN (18 patients)
OLIGURIA (17 patients)
GASTROINTESTINAL DISORDER (17 patients)
HAEMATOCHEZIA (17 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (17 patients)
HYPOTHYROIDISM (17 patients)
TRANSAMINASES INCREASED (17 patients)
OROPHARYNGEAL PAIN (17 patients)
CHRONIC MYELOID LEUKAEMIA (17 patients)
NEOPLASM PROGRESSION (17 patients)
METASTASES TO ADRENALS (16 patients)
LYMPHOCYTE COUNT DECREASED (16 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (16 patients)
MULTI-ORGAN FAILURE (16 patients)
FEAR (16 patients)
PANCREATIC CARCINOMA (16 patients)
HYPERSOMNIA (16 patients)
EPILEPSY (16 patients)
SUBARACHNOID HAEMORRHAGE (16 patients)
METASTASES TO LUNG (16 patients)
TACHYCARDIA (16 patients)
MUSCULAR WEAKNESS (16 patients)
KLEBSIELLA SEPSIS (16 patients)
MYOCARDIAL ISCHAEMIA (16 patients)
DYSGEUSIA (16 patients)
LUNG INFECTION (16 patients)
FAECES DISCOLOURED (16 patients)
PAIN OF SKIN (16 patients)
SPINAL FRACTURE (16 patients)
PANIC REACTION (16 patients)

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