About this FactMed analysis covering adverse side effect reports of STILNOX patients who developed ACANTHOLYSIS.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 2 individuals taking STILNOX reported ACANTHOLYSIS to the FDA. A total of 2193 STILNOX drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between STILNOX and ACANTHOLYSIS. In doing so, we compare STILNOX with other drugs that cause ACANTHOLYSIS, to help you evaluate whether or not STILNOX causes ACANTHOLYSIS. Likewise, this page shows the most highly-reported side effects of STILNOX, so you can see if ACANTHOLYSIS ranks among STILNOX's most well-known side effects.
Summary Statistics
Reports of STILNOX causing ACANTHOLYSIS: 2
Reports of any side effect of STILNOX : 2193
Percentage of STILNOX patients where ACANTHOLYSIS is a reported side effect: 0.0912%

FDA reports of any drug causing ACANTHOLYSIS : 33
Average percentage for all medicated patients where ACANTHOLYSIS is reported as a complication: 0.0002%

Physician opinion on STILNOX as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing STILNOX:
DRUG USE FOR UNKNOWN INDICATION ( 388 patients )
INSOMNIA ( 313 patients )
SLEEP DISORDER ( 126 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 32 patients )
ANXIETY ( 27 patients )
DEPRESSION ( 27 patients )
DRUG DEPENDENCE ( 8 patients )
SCHIZOPHRENIA ( 7 patients )
SLEEP DISORDER THERAPY ( 6 patients )
OVERDOSE ( 6 patients )
SOMNOLENCE ( 6 patients )
PROPHYLAXIS ( 6 patients )
INTENTIONAL OVERDOSE ( 6 patients )
ILL-DEFINED DISORDER ( 5 patients )
DRUG ABUSER ( 5 patients )
DRUG EXPOSURE DURING PREGNANCY ( 4 patients )
AGITATION ( 4 patients )
BIPOLAR I DISORDER ( 4 patients )
OFF LABEL USE ( 3 patients )
HYPNOTHERAPY ( 3 patients )
POISONING ( 3 patients )
INITIAL INSOMNIA ( 3 patients )
SEDATIVE THERAPY ( 3 patients )
MULTIPLE DRUG OVERDOSE INTENTIONAL ( 2 patients )
DYSTHYMIC DISORDER ( 2 patients )
BIPOLAR DISORDER ( 2 patients )
CARDIOMYOPATHY ( 2 patients )
INTENTIONAL MISUSE ( 2 patients )
MULTIPLE DRUG OVERDOSE ( 2 patients )
PAIN ( 2 patients )
UNEVALUABLE EVENT ( 2 patients )
SCHIZOAFFECTIVE DISORDER ( 2 patients )
SENILE DEMENTIA ( 2 patients )
OBSESSIVE-COMPULSIVE DISORDER ( 1 patients )
DRUG TOXICITY ( 1 patients )
STRESS ( 1 patients )
TACHYCARDIA ( 1 patients )
PANIC ATTACK ( 1 patients )
PSYCHOTIC DISORDER ( 1 patients )
CONVULSION ( 1 patients )
MENTAL DISORDER ( 1 patients )
DRUG ABUSE ( 1 patients )
SELF INJURIOUS BEHAVIOUR ( 1 patients )
DRUG ADMINISTRATION ERROR ( 1 patients )
MUSCLE RELAXANT THERAPY ( 1 patients )
SUICIDE ATTEMPT ( 1 patients )
ANXIETY DISORDER ( 1 patients )
INTENTIONAL DRUG MISUSE ( 1 patients )
CHILDHOOD PSYCHOSIS ( 1 patients )
MIDDLE INSOMNIA ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with ACANTHOLYSIS:

AMBIEN (10 patients)
ABRAXANE (9 patients)
ACIPHEX (9 patients)
AMPICILLIN (9 patients)
ASPIRIN (9 patients)
ATIVAN (9 patients)
AVASTIN (9 patients)
CYMBALTA (9 patients)
LEVOTHYROXINE SODIUM (9 patients)
NORCO (9 patients)
RADIATION (9 patients)
VICODIN (9 patients)
XELODA (9 patients)
ZOLOFT (9 patients)
ZOMETA (9 patients)
ZOFRAN (8 patients)
ARANESP (7 patients)
CAPECITABINE (7 patients)
CEFTRIAXONE (7 patients)
CEPHALEXIN (7 patients)
CIPROFLOXACIN (7 patients)
COLACE (7 patients)
DILAUDID (7 patients)
DOXIL (7 patients)
FEMARA (7 patients)
HYDROCODONE BITARTRATE AND ACETAMINOPHEN (7 patients)
KEFLEX (7 patients)
LASIX (7 patients)
LORAZEPAM (7 patients)
NAPROSYN (7 patients)
NEULASTA (7 patients)
NIACIN (7 patients)
PERCOCET (7 patients)
PROVIGIL (7 patients)
RITALIN (7 patients)
SYNTHROID (7 patients)
TAXOTERE (7 patients)
VANCOMYCIN (7 patients)
VANCOMYCIN HCL (7 patients)
DEXAMETHASONE (6 patients)
FENTANYL (6 patients)
CYCLOSPORINE (4 patients)
PLAVIX (4 patients)
RELAFEN (4 patients)
ACETYLSALICYLIC ACID SRT (3 patients)
ACYCLOVIR (3 patients)
AMITIZA (3 patients)
NABUMETONE (3 patients)
NEXIUM (3 patients)
NIFEDIPINE (3 patients)
XIFAXAN (3 patients)
ALDACTAZIDE (2 patients)
AMLOR (2 patients)
AZATHIOPRINE (2 patients)
CLINDAMYCIN (2 patients)
COZAAR (2 patients)
DEPAKENE (2 patients)
DEPAS (2 patients)
DIGOXIN (2 patients)
DIPYRIDAMOL (2 patients)
EMPYNASE (2 patients)
ENALAPRIL MALEATE (2 patients)
ETRETINATE (2 patients)
FRACTAL (2 patients)
FUCIDIN CREAM (2 patients)
FUROSEMIDE (2 patients)
GAMUNEX (2 patients)
GLUCOR (2 patients)
HALCION (2 patients)
ISOSORBIDE MONONITRATE (2 patients)
LAMICTAL (2 patients)
LAXOBERON (2 patients)
LEVEMIR (2 patients)
MAGLAX (2 patients)
METHYLPREDNISOLONE (2 patients)
MINOCYCLIN (2 patients)
MOPRAL (2 patients)
MORPHINE (2 patients)
NITROGLYCERIN (2 patients)
PREDNISOLONE (2 patients)
PREDNISONE (2 patients)
SECTRAL (2 patients)
STILNOX (2 patients)
THEOPHYLLINE (2 patients)
TOPICAL ANTISEPTICS (2 patients)
ACENOCOUMAROL (1 patients)
ACENOCOUMAROL (ACENOCOUMAROL) (1 patients)
ACTIFED (1 patients)
AMILORIDE (1 patients)
AMILORIDE (AMILORIDE HYDROCHLORIDE) (1 patients)
ARNESP (1 patients)
ATENOLOL (1 patients)
ATORVASTATIN CALCIUM (1 patients)
BEMYLID (1 patients)
BETAMETHASONE DIPROPIIONATE (1 patients)
BETAMETHASONE DIPROPIONATE (1 patients)
CARBAMAZEPINE (1 patients)
CEFIXIME (1 patients)
CILAZAPRIL (1 patients)
CIPROFLOXACIN HCL (1 patients)
CIPROFLOXACIN IV (1 patients)
CISPLATIN (1 patients)
COPEGUS (1 patients)
DEXAMETHASONE ACETATE (1 patients)
DOXIUM (CALCIUM DOBESILATE) (1 patients)
ETHYOL (1 patients)
ETOPOSIDE (1 patients)
FENTANYL-100 (1 patients)
FILGRASTIM (FILGRASTIM) (1 patients)
FINASTERIDE (1 patients)
GEMZAR (1 patients)
GLIBENCLAMIDE (1 patients)
GLIMEPIRIDE (1 patients)
HEMERAN GEL (HEPARINOID) (1 patients)
HUMAN INSULIN (1 patients)
INSULIN ACTRAPID HUMAN (1 patients)
INTRON A (1 patients)
IRINOTECAN HCL (1 patients)
L-THYROXIN (1 patients)
LACIDIPINE (1 patients)
LACIDIPINE (LACIDIPINE) (1 patients)
MAGNESIUM OXIDE (MAGNESIUM OXIDE) (1 patients)
METHOTREXATE (1 patients)
MS CONTIN (1 patients)
OXYCODONE HCL (1 patients)
PEG-INTRON (1 patients)
PHENYTOIN (1 patients)
PRAVASTATIN (1 patients)
PRAVASTATIN SODIUM (1 patients)
PREDNISONE TAB (1 patients)
RADIATION THERAPY (1 patients)
REBETOL (1 patients)
RIBAVIRIN (1 patients)
TAREG (1 patients)
TOPICAL MEDICATIONS (FOR PSORIASIS) (1 patients)
ZETIA (1 patients)
Most common side effects for patients taking STILNOX:
FALL (162 patients)
DRUG INTERACTION (143 patients)
CONFUSIONAL STATE (130 patients)
PYREXIA (100 patients)
SOMNOLENCE (96 patients)
HYPONATRAEMIA (89 patients)
VOMITING (86 patients)
MALAISE (75 patients)
DIARRHOEA (75 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (73 patients)
RENAL FAILURE ACUTE (71 patients)
AMNESIA (70 patients)
CHOLESTASIS (70 patients)
NAUSEA (69 patients)
ANAEMIA (68 patients)
RENAL FAILURE (66 patients)
CYTOLYTIC HEPATITIS (65 patients)
CONDITION AGGRAVATED (59 patients)
ASTHENIA (59 patients)
COMPLETED SUICIDE (58 patients)
LOSS OF CONSCIOUSNESS (57 patients)
OVERDOSE (57 patients)
DRUG EXPOSURE DURING PREGNANCY (56 patients)
DEPRESSION (55 patients)
DISORIENTATION (54 patients)
COMA (54 patients)
THROMBOCYTOPENIA (54 patients)
DEHYDRATION (54 patients)
HYPERTENSION (52 patients)
DEATH (49 patients)
DRUG INEFFECTIVE (49 patients)
DYSPNOEA (48 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (48 patients)
ROAD TRAFFIC ACCIDENT (48 patients)
PRURITUS (47 patients)
SOMNAMBULISM (47 patients)
HYPOTENSION (47 patients)
NEUTROPENIA (46 patients)
ALANINE AMINOTRANSFERASE INCREASED (45 patients)
SUICIDE ATTEMPT (45 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (45 patients)
INSOMNIA (44 patients)
INTENTIONAL OVERDOSE (42 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (42 patients)
HEADACHE (41 patients)
DEPRESSED LEVEL OF CONSCIOUSNESS (41 patients)
ABDOMINAL PAIN (39 patients)
HAEMOGLOBIN DECREASED (38 patients)
ANXIETY (37 patients)
HAEMATOMA (37 patients)
SEPTIC SHOCK (36 patients)
OEDEMA PERIPHERAL (36 patients)
JAUNDICE (35 patients)
TACHYCARDIA (35 patients)
ABNORMAL BEHAVIOUR (33 patients)
AGITATION (33 patients)
PAIN (33 patients)
CONVULSION (33 patients)
RHABDOMYOLYSIS (32 patients)
SEPSIS (32 patients)
DIZZINESS (31 patients)
AGGRESSION (30 patients)
DELIRIUM (30 patients)
C-REACTIVE PROTEIN INCREASED (29 patients)
VERTIGO (29 patients)
FATIGUE (28 patients)
CARDIAC FAILURE (28 patients)
DRUG ABUSER (28 patients)
HALLUCINATION (27 patients)
RASH MACULO-PAPULAR (27 patients)
HYPERKALAEMIA (27 patients)
TOXIC SKIN ERUPTION (26 patients)
RASH (26 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (26 patients)
LEUKOPENIA (25 patients)
HEPATITIS (25 patients)
ABDOMINAL PAIN UPPER (24 patients)
BLOOD CREATININE INCREASED (24 patients)
PULMONARY EMBOLISM (24 patients)
CHEST PAIN (24 patients)
ERYTHEMA (23 patients)
DRUG TOXICITY (23 patients)
DRUG RASH WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS (23 patients)
SLEEP WALKING (23 patients)
HYPOKALAEMIA (23 patients)
INTERSTITIAL LUNG DISEASE (23 patients)
AGRANULOCYTOSIS (22 patients)
EXTRAPYRAMIDAL DISORDER (22 patients)
TREMOR (22 patients)
SYNCOPE (22 patients)
WEIGHT INCREASED (22 patients)
ORTHOSTATIC HYPOTENSION (21 patients)
PURPURA (21 patients)
PNEUMONIA (21 patients)
BLOOD CREATINE PHOSPHOKINASE INCREASED (21 patients)
DISTURBANCE IN ATTENTION (21 patients)
DRUG DEPENDENCE (21 patients)
HEAD INJURY (20 patients)
HYPERTHERMIA (20 patients)
MENTAL DISORDER (20 patients)
MYALGIA (20 patients)
NERVOUSNESS (20 patients)
LEUKOCYTOSIS (20 patients)
LUNG DISORDER (20 patients)
EPILEPSY (20 patients)
SPEECH DISORDER (19 patients)
RECTAL HAEMORRHAGE (19 patients)
MELAENA (19 patients)
APHASIA (19 patients)
BACK PAIN (19 patients)
BALANCE DISORDER (19 patients)
MULTIPLE DRUG OVERDOSE INTENTIONAL (19 patients)
INTENTIONAL DRUG MISUSE (19 patients)
DRUG ABUSE (18 patients)
PNEUMONIA ASPIRATION (18 patients)
DYSPHAGIA (18 patients)
OFF LABEL USE (18 patients)
CEREBROVASCULAR ACCIDENT (18 patients)
HYPERHIDROSIS (18 patients)
GASTROINTESTINAL HAEMORRHAGE (18 patients)
ASCITES (18 patients)
CARDIAC ARREST (18 patients)
WEIGHT DECREASED (17 patients)
EOSINOPHILIA (17 patients)
MALNUTRITION (17 patients)
ANOREXIA (17 patients)
HEPATOCELLULAR INJURY (17 patients)
ATRIAL FIBRILLATION (17 patients)
DECREASED APPETITE (17 patients)
HEPATITIS CHOLESTATIC (17 patients)
PERIPHERAL ISCHAEMIA (17 patients)
TOXIC EPIDERMAL NECROLYSIS (16 patients)
SLEEP DISORDER (16 patients)
SUICIDAL IDEATION (16 patients)
VARICELLA (16 patients)
CONSTIPATION (16 patients)
BRADYCARDIA (16 patients)
RESPIRATORY DISTRESS (16 patients)
MYOCARDIAL INFARCTION (15 patients)
PANCYTOPENIA (15 patients)
ENCEPHALOPATHY (15 patients)
TRANSIENT ISCHAEMIC ATTACK (15 patients)
INFLAMMATION (15 patients)
PLEURAL EFFUSION (15 patients)
COLITIS ISCHAEMIC (15 patients)
RESPIRATORY FAILURE (15 patients)
UPPER LIMB FRACTURE (15 patients)
VISUAL ACUITY REDUCED (14 patients)
URINARY RETENTION (14 patients)
ARTHRALGIA (14 patients)
ILL-DEFINED DISORDER (14 patients)
CHILLS (14 patients)
MEMORY IMPAIRMENT (13 patients)
HAEMATEMESIS (13 patients)
SEROTONIN SYNDROME (13 patients)
HYPERTONIA (13 patients)
INFECTION (13 patients)
HEPATIC STEATOSIS (13 patients)
WITHDRAWAL SYNDROME (13 patients)
DRUG WITHDRAWAL SYNDROME (13 patients)
PREMATURE BABY (13 patients)
BLOOD PRESSURE SYSTOLIC INCREASED (13 patients)
GAIT DISTURBANCE (12 patients)
LEUKOCYTOCLASTIC VASCULITIS (12 patients)
DYSKINESIA (12 patients)
MYDRIASIS (12 patients)
OEDEMA (11 patients)
MALIGNANT NEOPLASM PROGRESSION (11 patients)
HYPOGLYCAEMIA (11 patients)
WHITE BLOOD CELL COUNT INCREASED (11 patients)
MUCOSAL INFLAMMATION (11 patients)
GRAND MAL CONVULSION (11 patients)
HEPATITIS FULMINANT (11 patients)
DISSEMINATED INTRAVASCULAR COAGULATION (11 patients)
URINARY TRACT INFECTION (11 patients)
SLEEP APNOEA SYNDROME (11 patients)
COUGH (11 patients)
PARAESTHESIA (11 patients)
EPISTAXIS (11 patients)
DYSPEPSIA (11 patients)
ELECTROCARDIOGRAM QT PROLONGED (11 patients)
PALLOR (11 patients)
CARDIO-RESPIRATORY ARREST (11 patients)
PAIN IN EXTREMITY (11 patients)
MUSCULAR WEAKNESS (11 patients)
INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION (11 patients)
OXYGEN SATURATION DECREASED (11 patients)
IMPAIRED HEALING (11 patients)
INCORRECT ROUTE OF DRUG ADMINISTRATION (11 patients)
ACUTE RESPIRATORY FAILURE (10 patients)
TINNITUS (10 patients)
ANGIOEDEMA (10 patients)
HYPOXIA (10 patients)
TOXICITY TO VARIOUS AGENTS (10 patients)
VASCULITIS (10 patients)
SUDDEN DEATH (10 patients)
PROTHROMBIN LEVEL DECREASED (10 patients)
PSYCHOMOTOR RETARDATION (10 patients)
GASTROINTESTINAL DISORDER (10 patients)
DYSARTHRIA (10 patients)
BLOOD UREA INCREASED (10 patients)
HAEMORRHAGE (10 patients)
HALLUCINATION, VISUAL (10 patients)
BACTERIAL SEPSIS (10 patients)
DEEP VEIN THROMBOSIS (10 patients)
HYPOTHERMIA (10 patients)
FEELING ABNORMAL (10 patients)
SELF INJURIOUS BEHAVIOUR (10 patients)
PERITONITIS (10 patients)
STAPHYLOCOCCAL INFECTION (9 patients)

In addition to reviewing our up-to-date FDA research, users may interact with the FactMed community - currently one million members and growing! FactMed online research and discussions are read by patients, scientists, physicians, and other interested health care parties. Post follow up Questions to learn from our diverse readership. Likewise, patients who have experienced unwanted effects are encouraged to share their Concerns to help educate and inform our members.


Recent FactMed Activity for STILNOX


Issue Description / Topic Timestamp
QUESTION
KIDNEY MALROTATION
side effects taking stilnox with neurifin plus 2014-12-16 06:19:22
QUESTION
MULTIPLE SCLEROSIS RELAPSE
does stilnox help the fatigue of ms 2015-01-18 15:26:58
QUESTION
MULTIPLE SCLEROSIS RELAPSE
Hi there. My wife (45) has Multiple Sclerosis. Will STILNOX assist her with MS at all. In the sense of brain damage? 2015-01-19 06:47:34
QUESTION
RHEUMATOID ARTHRITIS
i have rheumatoid arthritis, can i use stilnox? will it help? 2015-01-20 05:45:03
QUESTION
MULTIPLE SCLEROSIS RELAPSE
Does stilnox help for MS 2015-01-20 06:12:35
QUESTION
ARTHRITIS
I have reumotoide arthirithes can i use stillknox 2015-01-23 04:15:18
QUESTION
ARTHRITIS
I have reumotoide arthirithes can i use stillknox 2015-01-23 04:45:24
QUESTION
RHEUMATOID ARTHRITIS
Do stilknox have any side affects to rheumatoid artheritis 2015-01-23 04:53:36
QUESTION
AUTISM
Is it possible to administer stilnox to a child with autism 2015-01-28 09:29:07
QUESTION
MULTIPLE SCLEROSIS RELAPSE
Any problems with MS and Stilnox? lady, 61 diagnosed 24 years ago. In wheelchair, only right arm and strong and healthy brain and speech? Rest of body with strong nerve stimulus and reaction, ie....ants on skin 2015-03-24 10:34:05
QUESTION
MULTIPLE SCLEROSIS RELAPSE
Will taking 5-10mg Stillnox every evening cause MS relapse 2015-04-04 00:49:09
QUESTION
MYALGIA
is there a connection between myalgia and stillnox 2015-10-02 09:56:19
QUESTION
SYSTEMIC LUPUS ERYTHEMATOSUS
I have lupus and have been taking stillnox for years due to my insomnia. Since I started tetatrexat and plasmoquine i have been sleeping only for 2 hours a night even on stillnox. What else can I try for sleeping that will not interfere with the other medications? 2016-02-14 15:10:21
QUESTION
RESTLESSNESS
Does stilnox cause restlessness as a side effect ? 2016-03-04 07:30:25
QUESTION
RESTLESSNESS
Does stilnox cause restlessness as a side effect ? 2016-03-04 07:30:36
QUESTION
PERSONALITY CHANGE
does Stilnox cause personality change? My partner has changed, for the worse, since being on Stilnox for 2 years 2016-03-11 07:10:04
QUESTION
SLEEP TALKING
Is stilnox the reason for my sleep talking? 2017-04-11 04:23:07

My Patient Resources

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Your Question:

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Your Experience or Concern:

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