About this FactMed analysis covering adverse side effect reports of VOTRIENT patients who developed AKINESIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 2 individuals taking VOTRIENT reported AKINESIA to the FDA. A total of 1899 VOTRIENT drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between VOTRIENT and AKINESIA. In doing so, we compare VOTRIENT with other drugs that cause AKINESIA, to help you evaluate whether or not VOTRIENT causes AKINESIA. Likewise, this page shows the most highly-reported side effects of VOTRIENT, so you can see if AKINESIA ranks among VOTRIENT's most well-known side effects.
Summary Statistics
Reports of VOTRIENT causing AKINESIA: 2
Reports of any side effect of VOTRIENT : 1899
Percentage of VOTRIENT patients where AKINESIA is a reported side effect: 0.1053%

FDA reports of any drug causing AKINESIA : 753
Average percentage for all medicated patients where AKINESIA is reported as a complication: 0.0047%

Physician opinion on VOTRIENT as adverse event culprit:

Overall opinion for all reports of this drug:
Most frequent diagnoses/indications for prescribing VOTRIENT:
RENAL CANCER ( 351 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 337 patients )
RENAL CELL CARCINOMA ( 267 patients )
RENAL CANCER METASTATIC ( 76 patients )
METASTATIC RENAL CELL CARCINOMA ( 62 patients )
NEOPLASM MALIGNANT ( 36 patients )
SARCOMA ( 32 patients )
MALIGNANT SOFT TISSUE NEOPLASM ( 31 patients )
THYROID CANCER ( 21 patients )
NEOPLASM ( 15 patients )
NON-SMALL CELL LUNG CANCER ( 13 patients )
LUNG NEOPLASM MALIGNANT ( 13 patients )
MALIGNANT URINARY TRACT NEOPLASM ( 12 patients )
DRUG USE FOR UNKNOWN INDICATION ( 11 patients )
LEIOMYOSARCOMA ( 7 patients )
BREAST CANCER ( 6 patients )
OVARIAN NEOPLASM ( 5 patients )
PROSTATE CANCER ( 5 patients )
OVARIAN CANCER ( 5 patients )
SYNOVIAL SARCOMA METASTATIC ( 4 patients )
GASTROINTESTINAL STROMAL TUMOUR ( 4 patients )
BLADDER CANCER ( 4 patients )
HEPATIC NEOPLASM MALIGNANT ( 4 patients )
MALIGNANT NEOPLASM OF RENAL PELVIS ( 4 patients )
SYNOVIAL SARCOMA ( 3 patients )
DESMOPLASTIC SMALL ROUND CELL TUMOUR ( 3 patients )
BRONCHIAL CARCINOMA ( 3 patients )
SMALL CELL LUNG CANCER STAGE UNSPECIFIED ( 3 patients )
MALIGNANT MELANOMA ( 2 patients )
THYROID CANCER METASTATIC ( 2 patients )
UTERINE CANCER ( 2 patients )
RENAL CELL CARCINOMA STAGE IV ( 2 patients )
NEUROENDOCRINE CARCINOMA ( 2 patients )
TRANSITIONAL CELL CANCER OF THE RENAL PELVIS AND URETER ( 2 patients )
PULMONARY HYPERTENSION ( 2 patients )
METASTASIS ( 2 patients )
BONE NEOPLASM MALIGNANT ( 2 patients )
RENAL NEOPLASM ( 2 patients )
CHONDROSARCOMA METASTATIC ( 2 patients )
NEUROENDOCRINE TUMOUR ( 2 patients )
LUNG DISORDER ( 1 patients )
DERMATOFIBROSARCOMA ( 1 patients )
OFF LABEL USE ( 1 patients )
TRANSITIONAL CELL CARCINOMA ( 1 patients )
EWING'S SARCOMA ( 1 patients )
ANGIOSARCOMA ( 1 patients )
METASTASES TO LUNG ( 1 patients )
METASTATIC NEOPLASM ( 1 patients )
GLIOMA ( 1 patients )
RENAL CANCER STAGE IV ( 1 patients )
BRAIN NEOPLASM ( 1 patients )
MULTIPLE MYELOMA ( 1 patients )
CARCINOID SYNDROME ( 1 patients )
LUNG CANCER METASTATIC ( 1 patients )
COLON CANCER ( 1 patients )
ENDOMETRIAL SARCOMA ( 1 patients )
ADENOID CYSTIC CARCINOMA ( 1 patients )
URINARY TRACT NEOPLASM ( 1 patients )
GASTROINTESTINAL CANCER METASTATIC ( 1 patients )
BASAL CELL CARCINOMA ( 1 patients )
GENITOURINARY TRACT NEOPLASM ( 1 patients )
HEPATIC LESION ( 1 patients )
BRAIN NEOPLASM MALIGNANT ( 1 patients )
NASOPHARYNGEAL CANCER ( 1 patients )
INFLAMMATORY CARCINOMA OF THE BREAST ( 1 patients )
LEIOMYOSARCOMA METASTATIC ( 1 patients )
( 0 patients )
Drugs with high FDA adverse event association with AKINESIA:

MODOPAR (292 patients)
EFFEXOR (145 patients)
XANAX (129 patients)
VIOXX (116 patients)
STALEVO 100 (111 patients)
ASPIRIN (73 patients)
PERGOLIDE MESYLATE (56 patients)
SINEMET (55 patients)
RISPERDAL (54 patients)
ATHYMIL (52 patients)
COMTAN (45 patients)
MADOPAR (41 patients)
LORAZEPAM (40 patients)
MADOPAR DISPERSIBLE (39 patients)
IMOVANE (38 patients)
ZYPREXA (37 patients)
ATARAX (37 patients)
VALPROATE SODIUM (36 patients)
CLOZAPINE (31 patients)
DEPAKOTE (30 patients)
CITALOPRAM HYDROBROMIDE (29 patients)
CLOBAZAM (29 patients)
FUROSEMIDE (28 patients)
REQUIP (28 patients)
PARLODEL (27 patients)
EXELON (27 patients)
PAXIL (26 patients)
DIGOXIN (25 patients)
LASIX (25 patients)
ERYTHROMYCIN (25 patients)
SEROQUEL (25 patients)
LAMOTRIGINE (25 patients)
RISPERIDONE (24 patients)
GENTAMICIN (24 patients)
PHENYTOIN (23 patients)
AMANTADINE HCL (23 patients)
ACETAMINOPHEN (21 patients)
HALDOL (21 patients)
DIAZEPAM (20 patients)
VALTREX (20 patients)
OMEPRAZOLE (19 patients)
PAROXETINE HCL (19 patients)
ACETAMINOPHEN AND TRAMADOL HCL (18 patients)
CEFOTAXIME (18 patients)
SPIRONOLACTONE (18 patients)
LEVOTHYROXINE SODIUM (18 patients)
TEGRETOL (17 patients)
PREDNISOLONE (17 patients)
DEPAKENE (17 patients)
HALOPERIDOL (17 patients)
SIMVASTATIN (16 patients)
NITROGLYCERIN (16 patients)
ZOLOFT (15 patients)
PIPERACILLIN (15 patients)
LIPITOR (15 patients)
LEXOMIL (14 patients)
CLOPIDOGREL (14 patients)
OLANZAPINE (14 patients)
CABERGOLINE (14 patients)
TEMESTA (14 patients)
CLONAZEPAM (14 patients)
IBUPROFEN (14 patients)
NEURONTIN (13 patients)
LEVODOPA (13 patients)
WARFARIN SODIUM (13 patients)
SERENACE (13 patients)
OXYCONTIN (13 patients)
MEMANTINE HCL (13 patients)
ATENOLOL (13 patients)
DIOVAN (12 patients)
HIZENTRA (12 patients)
PRAMIPEXOLE DIHYDROCHLORIDE (12 patients)
ALBUTEROL (12 patients)
CELEBREX (12 patients)
HEPARIN (12 patients)
SEROQUEL XR (12 patients)
ENOXAPARIN SODIUM (12 patients)
ATORVASTATIN CALCIUM (12 patients)
ABILIFY (11 patients)
PLAVIX (11 patients)
FLUOXETINE (11 patients)
LOXAPINE HCL (11 patients)
COREG (11 patients)
TAXOTERE (11 patients)
GLEEVEC (11 patients)
VENLAFAXINE (11 patients)
PREVACID (11 patients)
CAPTOPRIL (11 patients)
CIPRO (11 patients)
CYCLOSPORINE (11 patients)
LANTUS (10 patients)
SYNTHROID (10 patients)
ACTONEL (10 patients)
MIRAPEX (10 patients)
KETOCONAZOLE (10 patients)
ANTIBIOTICS (10 patients)
ARICEPT (10 patients)
HEPARIN SODIUM INJECTION (10 patients)
AVONEX (10 patients)
RAMIPRIL (9 patients)
INSULIN (9 patients)
NECYRANE (9 patients)
MORPHINE (9 patients)
FERROUS SULFATE TAB (9 patients)
PRAZEPAM (9 patients)
DONEPEZIL HCL (9 patients)
CARBOCISTEINE (9 patients)
EXTAVIA (9 patients)
BROMOCRIPTINE MESYLATE (9 patients)
AMBIEN (9 patients)
AMOXICILLIN (9 patients)
RISPERDAL CONSTA (9 patients)
LAMICTAL (9 patients)
SINGULAIR (9 patients)
ECONAZOLE NITRATE (9 patients)
ARTANE (9 patients)
FOLIC ACID (9 patients)
PRAMIPEXOLE DIHYCHLLORIDE (9 patients)
LISINOPRIL (9 patients)
CEFUROXIME (9 patients)
LYSOPAINE (9 patients)
PRILOSEC (9 patients)
HYDROCHLOROTHIAZIDE (9 patients)
SANDIMMUNE (9 patients)
CYMBALTA (8 patients)
ELUDRIL (8 patients)
MIRTAZAPINE (8 patients)
SOLANAX (8 patients)
EPINEPHRINE (8 patients)
TYLENOL (CAPLET) (8 patients)
CIATYL Z (8 patients)
TRAMAL (8 patients)
AMIODARONE HCL (8 patients)
COUMADIN (8 patients)
NEUROCIL (8 patients)
OXAZEPAM (8 patients)
LEVEMIR (8 patients)
AVANDIA (8 patients)
NEXIUM (8 patients)
PROTONIX (8 patients)
ZOCOR (8 patients)
WELLBUTRIN (8 patients)
BIPERIDEN HYDROCHLORIDE TAB (8 patients)
METFORMIN HCL (7 patients)
NORVASC (7 patients)
METOPROLOL (7 patients)
TRIVASTAL (7 patients)
ZANAFLEX (7 patients)
HUMIRA (7 patients)
ALDACTONE (7 patients)
SOLU-CORTEF (7 patients)
ALLOPURINOL (7 patients)
TRIHEXYPHENIDYL HCL (7 patients)
PREVISCAN (7 patients)
DOPAMINE HCL (7 patients)
SERTRALINE HCL (7 patients)
THIOPENTAL SODIUM (7 patients)
ENALAPRIL MALEATE (7 patients)
BISOPROLOL FUMARATE (7 patients)
TRAZODONE HCL (7 patients)
LITHIUM CARBONATE (7 patients)
TYLENOL (7 patients)
TRANXENE (7 patients)
POTASSIUM CHLORIDE (7 patients)
CEFOTAXIME SODIUM (7 patients)
PREDONINE (7 patients)
ISOSORBIDE DINITRATE (7 patients)
CYTARABINE (7 patients)
VITAMIN D (7 patients)
CARBIDOPA AND LEVODOPA (6 patients)
LOVENOX (6 patients)
ACETYLSALICYLIC ACID SRT (6 patients)
ESCITALOPRAM (6 patients)
DEXAMETHASONE TAB (6 patients)
SERTRALINE HYDROCHLORIDE (6 patients)
EVEROLIMUS (6 patients)
TASMAR (6 patients)
ALPRAZOLAM (6 patients)
MANTADIX (6 patients)
PRAZINE (6 patients)
HERCEPTIN (6 patients)
DEROXAT (6 patients)
AMLODIPINE (6 patients)
METHYLPREDNISOLONE (6 patients)
PURSENNID (6 patients)
REMICADE (6 patients)
SILECE (6 patients)
ZOVIRAX (6 patients)
MYCOPHENOLATE MOFETIL (6 patients)
ARAVA (6 patients)
LEPTICUR (6 patients)
CARBAMAZEPINE (6 patients)
TOBRAMYCIN (6 patients)
SYMMETREL (6 patients)
ATIVAN (6 patients)
ATORVASTATIN (6 patients)
CIPRALEX (ESCITALOPRAM) (6 patients)
LYRICA (6 patients)
CLARITHROMYCIN (6 patients)
CITALOPRAM (6 patients)
VANCOMYCIN (6 patients)
HEPTAMINOL (6 patients)
AZILECT (6 patients)
HUMALOG (6 patients)
PREDNISONE TAB (6 patients)
PROPRANOLOL (6 patients)
PROCTOLOG (6 patients)
INTETRIX (6 patients)
RANITIDINE (6 patients)
MS CONTIN (5 patients)
Most common side effects for patients taking VOTRIENT:
DEATH (276 patients)
FATIGUE (266 patients)
DIARRHOEA (246 patients)
NAUSEA (217 patients)
VOMITING (117 patients)
HYPERTENSION (116 patients)
DECREASED APPETITE (109 patients)
DRUG INEFFECTIVE (99 patients)
BLOOD PRESSURE INCREASED (89 patients)
HEADACHE (73 patients)
DYSPNOEA (67 patients)
ASTHENIA (62 patients)
NEOPLASM MALIGNANT (61 patients)
DISEASE PROGRESSION (61 patients)
HAIR COLOUR CHANGES (60 patients)
WEIGHT DECREASED (59 patients)
ABDOMINAL PAIN UPPER (57 patients)
ABDOMINAL PAIN (53 patients)
LIVER FUNCTION TEST ABNORMAL (49 patients)
ALANINE AMINOTRANSFERASE INCREASED (47 patients)
DYSGEUSIA (41 patients)
DIZZINESS (41 patients)
RASH (40 patients)
ALOPECIA (40 patients)
BLOOD BILIRUBIN INCREASED (40 patients)
HEPATIC ENZYME INCREASED (39 patients)
OFF LABEL USE (39 patients)
ASPARTATE AMINOTRANSFERASE INCREASED (38 patients)
COUGH (37 patients)
PAIN (36 patients)
BACK PAIN (35 patients)
MALAISE (35 patients)
JAUNDICE (35 patients)
RENAL CANCER (31 patients)
PAIN IN EXTREMITY (31 patients)
CONSTIPATION (31 patients)
GAIT DISTURBANCE (26 patients)
PYREXIA (26 patients)
ARTHRALGIA (25 patients)
HOSPITALISATION (25 patients)
ADVERSE DRUG REACTION (24 patients)
PRURITUS (24 patients)
DEHYDRATION (24 patients)
OEDEMA PERIPHERAL (23 patients)
PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME (22 patients)
ADVERSE EVENT (22 patients)
CHEST PAIN (22 patients)
HEPATOTOXICITY (22 patients)
ABDOMINAL DISCOMFORT (21 patients)
MUSCLE SPASMS (21 patients)
HYPOTHYROIDISM (21 patients)
STOMATITIS (20 patients)
MUSCULAR WEAKNESS (20 patients)
DYSPHONIA (19 patients)
BLISTER (19 patients)
PLEURAL EFFUSION (19 patients)
DYSPEPSIA (19 patients)
CEREBROVASCULAR ACCIDENT (19 patients)
CONFUSIONAL STATE (19 patients)
AGEUSIA (18 patients)
LUNG DISORDER (18 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (17 patients)
INSOMNIA (17 patients)
ILL-DEFINED DISORDER (17 patients)
VISUAL IMPAIRMENT (16 patients)
ANAEMIA (16 patients)
PNEUMONIA (16 patients)
CHROMATURIA (16 patients)
HYPOAESTHESIA (16 patients)
ERYTHEMA (15 patients)
FALL (15 patients)
FEELING ABNORMAL (14 patients)
EPISTAXIS (14 patients)
NEOPLASM PROGRESSION (14 patients)
RENAL FAILURE (13 patients)
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION (13 patients)
THROMBOCYTOPENIA (13 patients)
ORAL PAIN (13 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (13 patients)
PLATELET COUNT DECREASED (13 patients)
VISION BLURRED (13 patients)
DRY SKIN (13 patients)
CHEST DISCOMFORT (13 patients)
CONVULSION (13 patients)
MALIGNANT NEOPLASM PROGRESSION (12 patients)
HYPOTENSION (12 patients)
RED BLOOD CELL COUNT DECREASED (12 patients)
BLOOD CREATININE INCREASED (12 patients)
TACHYCARDIA (12 patients)
METASTASES TO LUNG (12 patients)
RETCHING (12 patients)
DRUG INTOLERANCE (12 patients)
SKIN EXFOLIATION (11 patients)
HEPATITIS (11 patients)
SEPSIS (11 patients)
SKIN ULCER (11 patients)
HAEMORRHAGE (11 patients)
WHITE BLOOD CELL COUNT DECREASED (11 patients)
MUCOSAL INFLAMMATION (11 patients)
HAEMOPTYSIS (11 patients)
PANCREATITIS (11 patients)
GASTROINTESTINAL DISORDER (11 patients)
SKIN DISCOLOURATION (10 patients)
MYALGIA (10 patients)
URINARY TRACT INFECTION (10 patients)
CARDIAC DISORDER (10 patients)
DYSPHAGIA (10 patients)
PULMONARY EMBOLISM (10 patients)
CONTUSION (10 patients)
HYPONATRAEMIA (10 patients)
THERAPEUTIC RESPONSE UNEXPECTED (10 patients)
LIVER DISORDER (10 patients)
DRUG INTERACTION (10 patients)
LETHARGY (9 patients)
ANXIETY (9 patients)
APHONIA (9 patients)
PERICARDIAL EFFUSION (9 patients)
HEPATIC FAILURE (9 patients)
RENAL IMPAIRMENT (9 patients)
NEUTROPENIA (9 patients)
BLOOD POTASSIUM INCREASED (9 patients)
PNEUMOTHORAX (9 patients)
MOUTH ULCERATION (9 patients)
CHILLS (9 patients)
THROMBOSIS (9 patients)
HYPOGLYCAEMIA (8 patients)
OROPHARYNGEAL PAIN (8 patients)
ARRHYTHMIA (8 patients)
BALANCE DISORDER (8 patients)
HYPERGLYCAEMIA (8 patients)
GLOSSODYNIA (8 patients)
POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME (8 patients)
WHEEZING (8 patients)
RENAL CELL CARCINOMA (8 patients)
CONDITION AGGRAVATED (8 patients)
HYPERTENSIVE CRISIS (8 patients)
SENSORY DISTURBANCE (8 patients)
RHINORRHOEA (8 patients)
DEPRESSION (8 patients)
INTESTINAL PERFORATION (8 patients)
FLATULENCE (8 patients)
NASOPHARYNGITIS (7 patients)
SKIN DEPIGMENTATION (7 patients)
TREATMENT FAILURE (7 patients)
HEPATIC FUNCTION ABNORMAL (7 patients)
HAEMATOCHEZIA (7 patients)
BLINDNESS (7 patients)
METASTATIC RENAL CELL CARCINOMA (7 patients)
LOSS OF CONSCIOUSNESS (7 patients)
PROTEINURIA (7 patients)
HAEMOGLOBIN DECREASED (7 patients)
NECK PAIN (7 patients)
HEPATIC ENZYME ABNORMAL (7 patients)
RASH PRURITIC (7 patients)
OEDEMA (7 patients)
RETINAL DETACHMENT (7 patients)
GAMMA-GLUTAMYLTRANSFERASE INCREASED (7 patients)
DRUG ADMINISTRATION ERROR (7 patients)
HAEMOGLOBIN INCREASED (6 patients)
HAIR TEXTURE ABNORMAL (6 patients)
ACUTE RESPIRATORY DISTRESS SYNDROME (6 patients)
GLOBULINS INCREASED (6 patients)
HYPERHIDROSIS (6 patients)
TINNITUS (6 patients)
HEART RATE DECREASED (6 patients)
BLOOD GLUCOSE DECREASED (6 patients)
OROPHARYNGEAL BLISTERING (6 patients)
ONYCHOCLASIS (6 patients)
PALPITATIONS (6 patients)
BODY TEMPERATURE DECREASED (6 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (6 patients)
GLOMERULAR FILTRATION RATE DECREASED (6 patients)
PROTEIN TOTAL INCREASED (6 patients)
HYPERAESTHESIA (6 patients)
MIGRAINE (6 patients)
DEAFNESS (6 patients)
INCREASED TENDENCY TO BRUISE (6 patients)
INFECTION (6 patients)
SYNCOPE (6 patients)
THYROID DISORDER (5 patients)
HYPERSOMNIA (5 patients)
PNEUMONITIS (5 patients)
MONOPLEGIA (5 patients)
HOSPICE CARE (5 patients)
NIGHT SWEATS (5 patients)
PRODUCTIVE COUGH (5 patients)
ASTHMA (5 patients)
TRANSFUSION (5 patients)
EJECTION FRACTION DECREASED (5 patients)
PULMONARY THROMBOSIS (5 patients)
BLOOD ALKALINE PHOSPHATASE DECREASED (5 patients)
OCULAR ICTERUS (5 patients)
BLOOD LACTATE DEHYDROGENASE INCREASED (5 patients)
YELLOW SKIN (5 patients)
SOMNOLENCE (5 patients)
SURGERY (5 patients)
POLYCYTHAEMIA (5 patients)
BRAIN OEDEMA (5 patients)
TRANSAMINASES INCREASED (5 patients)
MENTAL STATUS CHANGES (5 patients)
BURNING SENSATION (5 patients)
FURUNCLE (5 patients)
HIP SURGERY (5 patients)
EYE PAIN (5 patients)
HYPERLIPIDAEMIA (5 patients)
ENCEPHALOPATHY (5 patients)
INCREASED APPETITE (5 patients)
DISCOMFORT (5 patients)
SLEEP DISORDER (5 patients)
DISORIENTATION (5 patients)

In addition to reviewing our up-to-date FDA research, users may interact with the FactMed community - currently one million members and growing! FactMed online research and discussions are read by patients, scientists, physicians, and other interested health care parties. Post follow up Questions to learn from our diverse readership. Likewise, patients who have experienced unwanted effects are encouraged to share their Concerns to help educate and inform our members.


Recent FactMed Activity for VOTRIENT


Issue Description / Topic Timestamp
QUESTION
PROTEINURIA
My protein is 160. My protein creatine ratio is 131 and i am on votrient, does anybody know what this means? 2015-07-10 20:20:14
QUESTION
SUNBURN
I got bad sunburn. And start filling very painful my lag mussels. Can it be because I'm talking votrient? 2016-04-03 06:29:47
QUESTION
DERMATITIS
I got a sunburn on my right arm and hand while driving for 2 days with the sun on that arm. Then I developed blisters, that has lasted over 1 month, and is slowly spreading up my arm, and now has started on my other hand, that did not get a sunburn. Is this a side effect of Votrient? 2016-10-02 20:14:20
QUESTION
PANCREATITIS
I have pacreatitis caused bij Votrient. What can I do about it? Is it dangerous? 2017-10-24 03:15:30
QUESTION
CHILLS
Sudden chills an shaking for about 30 min, I felt pretty good before except for a back ache. it was warm in my house. I finished my light dinner an bam !any ideas 2018-02-13 21:51:37

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