Is PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA a side effect of ZOMETA ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of ZOMETA patients who developed PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 14 individuals taking ZOMETA reported PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA to the FDA. A total of 43540 ZOMETA drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between ZOMETA and PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA. In doing so, we compare ZOMETA with other drugs that cause PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA, to help you evaluate whether or not ZOMETA causes PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA. Likewise, this page shows the most highly-reported side effects of ZOMETA, so you can see if PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA ranks among ZOMETA's most well-known side effects.

Summary Statistics
Reports of ZOMETA causing PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA: 14
Reports of any side effect of ZOMETA : 43540
Percentage of ZOMETA patients where PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA is a reported side effect: 0.0322%

FDA reports of any drug causing PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA : 168
Average percentage for all medicated patients where PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA is reported as a complication: 0.0011%

Physician opinion on ZOMETA as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing ZOMETA:

METASTASES TO BONE ( 8057 patients )
MULTIPLE MYELOMA ( 4343 patients )
BREAST CANCER ( 1789 patients )
BREAST CANCER METASTATIC ( 1492 patients )
PROSTATE CANCER ( 1187 patients )
PROSTATE CANCER METASTATIC ( 1018 patients )
OSTEOPOROSIS ( 939 patients )
NEOPLASM MALIGNANT ( 467 patients )
DRUG USE FOR UNKNOWN INDICATION ( 430 patients )
BONE DISORDER ( 364 patients )
PROPHYLAXIS ( 327 patients )
HYPERCALCAEMIA ( 309 patients )
HYPERCALCAEMIA OF MALIGNANCY ( 255 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 208 patients )
BONE LESION ( 200 patients )
RENAL CELL CARCINOMA ( 142 patients )
LUNG NEOPLASM MALIGNANT ( 135 patients )
BONE NEOPLASM MALIGNANT ( 133 patients )
BONE LOSS ( 124 patients )
PLASMACYTOMA ( 122 patients )
METASTASIS ( 121 patients )
BONE DENSITY DECREASED ( 106 patients )
LUNG CANCER METASTATIC ( 106 patients )
BONE PAIN ( 85 patients )
METASTATIC RENAL CELL CARCINOMA ( 85 patients )
OSTEOPOROSIS PROPHYLAXIS ( 83 patients )
OSTEOLYSIS ( 73 patients )
RESORPTION BONE INCREASED ( 72 patients )
OSTEOPENIA ( 71 patients )
BREAST CANCER FEMALE ( 65 patients )
METASTASES TO SPINE ( 59 patients )
RENAL CANCER ( 51 patients )
METASTATIC NEOPLASM ( 49 patients )
BONE DENSITY ABNORMAL ( 39 patients )
CALCIUM DEFICIENCY ( 33 patients )
RENAL CELL CARCINOMA STAGE UNSPECIFIED ( 30 patients )
METASTASES TO LUNG ( 28 patients )
PROSTATE CANCER STAGE IV ( 27 patients )
BONE CANCER METASTATIC ( 24 patients )
OSTEITIS DEFORMANS ( 24 patients )
METASTASES TO PROSTATE ( 24 patients )
NON-HODGKIN'S LYMPHOMA ( 22 patients )
BREAST CANCER STAGE IV ( 20 patients )
METASTASES TO BREAST ( 20 patients )
RENAL CANCER METASTATIC ( 19 patients )
NON-SMALL CELL LUNG CANCER ( 19 patients )
LYMPHOMA ( 18 patients )
ILL-DEFINED DISORDER ( 18 patients )
SPINAL FRACTURE ( 17 patients )
LEIOMYOSARCOMA ( 16 patients )
COLON CANCER ( 15 patients )
CANCER PAIN ( 15 patients )
NEOPLASM PROSTATE ( 15 patients )
BREAST NEOPLASM ( 15 patients )
METASTASES TO LIVER ( 15 patients )
COMPLEX REGIONAL PAIN SYNDROME ( 14 patients )
PREMEDICATION ( 13 patients )
METASTASES TO CENTRAL NERVOUS SYSTEM ( 13 patients )
SARCOIDOSIS ( 12 patients )
NEOPLASM ( 12 patients )
NON-SMALL CELL LUNG CANCER METASTATIC ( 11 patients )
BRONCHIAL CARCINOMA ( 11 patients )
RECTAL CANCER ( 11 patients )
FRACTURE ( 11 patients )
PAIN ( 11 patients )
NEUROENDOCRINE CARCINOMA ( 11 patients )
CALCIUM METABOLISM DISORDER ( 10 patients )
BONE EROSION ( 10 patients )
BLADDER CANCER ( 10 patients )
FIBROUS DYSPLASIA OF BONE ( 10 patients )
COLORECTAL CANCER METASTATIC ( 10 patients )
BRAIN NEOPLASM ( 9 patients )
LUNG ADENOCARCINOMA METASTATIC ( 9 patients )
RENAL CELL CARCINOMA STAGE IV ( 9 patients )
GAUCHER'S DISEASE ( 9 patients )
PATHOLOGICAL FRACTURE ( 9 patients )
BONE NEOPLASM ( 8 patients )
MALIGNANT MELANOMA ( 8 patients )
HYPERGAMMAGLOBULINAEMIA BENIGN MONOCLONAL ( 8 patients )
OSTEONECROSIS ( 8 patients )
LUNG ADENOCARCINOMA ( 8 patients )
GLIOBLASTOMA MULTIFORME ( 8 patients )
OSTEOGENESIS IMPERFECTA ( 7 patients )
BACK PAIN ( 7 patients )
HEPATIC NEOPLASM MALIGNANT ( 7 patients )
EWING'S SARCOMA ( 7 patients )
OSTEOARTHRITIS ( 7 patients )
CHEMOTHERAPY ( 6 patients )
TRANSITIONAL CELL CARCINOMA ( 6 patients )
METASTATIC PAIN ( 6 patients )
JUVENILE CHRONIC MYELOMONOCYTIC LEUKAEMIA ( 6 patients )
SKELETAL INJURY ( 6 patients )
ANALGESIC THERAPY ( 6 patients )
BREAST CANCER RECURRENT ( 6 patients )
HEPATIC CANCER METASTATIC ( 5 patients )
HODGKIN'S DISEASE ( 5 patients )
URETERIC CANCER METASTATIC ( 5 patients )
GASTROINTESTINAL CARCINOMA ( 5 patients )
METASTASES TO KIDNEY ( 5 patients )
BENIGN BONE NEOPLASM ( 5 patients )
METASTASES TO NECK ( 5 patients )
BONE SARCOMA ( 5 patients )
BREAST CANCER MALE ( 5 patients )
CERVIX CARCINOMA ( 5 patients )
THYMIC CANCER METASTATIC ( 5 patients )
BLADDER TRANSITIONAL CELL CARCINOMA ( 4 patients )
LYMPHOPLASMACYTOID LYMPHOMA/IMMUNOCYTOMA ( 4 patients )
OESOPHAGEAL CARCINOMA ( 4 patients )
UTERINE CANCER ( 4 patients )
GASTRIC CANCER ( 4 patients )
RHEUMATOID ARTHRITIS ( 4 patients )
HEAD AND NECK CANCER ( 4 patients )
ENDOMETRIAL CANCER ( 4 patients )
ROUTINE HEALTH MAINTENANCE ( 4 patients )
BLOOD CALCIUM INCREASED ( 4 patients )
PHAEOCHROMOCYTOMA ( 4 patients )
SARCOMA ( 4 patients )
HORMONE THERAPY ( 4 patients )
PLASMACYTOSIS ( 4 patients )
ADJUVANT THERAPY ( 4 patients )
CARCINOID TUMOUR ( 4 patients )
HYPERKALAEMIA ( 4 patients )
VITAMIN SUPPLEMENTATION ( 4 patients )
RENAL NEOPLASM ( 4 patients )
WALDENSTROM'S MACROGLOBULINAEMIA ( 4 patients )
PROSTATE CANCER RECURRENT ( 3 patients )
METASTASES TO PELVIS ( 3 patients )
BREAST DISORDER MALE ( 3 patients )
METASTATIC BRONCHIAL CARCINOMA ( 3 patients )
COLORECTAL CANCER ( 3 patients )
PAIN MANAGEMENT ( 3 patients )
BONE DEVELOPMENT ABNORMAL ( 3 patients )
LUNG ADENOCARCINOMA STAGE IV ( 3 patients )
PALLIATIVE CARE ( 3 patients )
LUNG CARCINOMA CELL TYPE UNSPECIFIED STAGE 0 ( 3 patients )
DRUG THERAPY ( 3 patients )
NEUROENDOCRINE TUMOUR ( 3 patients )
CHEST PAIN ( 3 patients )
LARGE INTESTINE CARCINOMA ( 3 patients )
PROSTATIC DISORDER ( 3 patients )
OVARIAN CANCER ( 3 patients )
BLOOD PRESSURE ( 3 patients )
METASTATIC CARCINOID TUMOUR ( 3 patients )
MASTOCYTOSIS ( 3 patients )
GAMMOPATHY ( 3 patients )
PRECURSOR T-LYMPHOBLASTIC LYMPHOMA/LEUKAEMIA ( 3 patients )
COMPRESSION FRACTURE ( 3 patients )
METASTASES TO BONE MARROW ( 3 patients )
B-CELL LYMPHOMA ( 3 patients )
MYELITIS ( 2 patients )
THYROID CANCER METASTATIC ( 2 patients )
DYSPLASIA ( 2 patients )
NON-HODGKIN'S LYMPHOMA STAGE IV ( 2 patients )
BLOOD CALCIUM DECREASED ( 2 patients )
NAUSEA ( 2 patients )
LIP AND/OR ORAL CAVITY CANCER ( 2 patients )
METASTATIC CARCINOMA OF THE BLADDER ( 2 patients )
SKELETON DYSPLASIA ( 2 patients )
ADULT T-CELL LYMPHOMA/LEUKAEMIA ( 2 patients )
NEOPLASM PROGRESSION ( 2 patients )
ANXIETY ( 2 patients )
CROHN'S DISEASE ( 2 patients )
CARCINOID TUMOUR PULMONARY ( 2 patients )
SPINAL DISORDER ( 2 patients )
DISEASE COMPLICATION ( 2 patients )
NEUROECTODERMAL NEOPLASM ( 2 patients )
VOMITING ( 2 patients )
CARCINOMA IN SITU OF SKIN ( 2 patients )
BREAST CANCER STAGE I ( 2 patients )
BREAST CANCER STAGE III ( 2 patients )
OSTEOPOROSIS POSTMENOPAUSAL ( 2 patients )
PROSTATE CANCER STAGE III ( 2 patients )
BREAST DISORDER ( 2 patients )
CHRONIC MYELOID LEUKAEMIA ( 2 patients )
MALIGNANT HISTIOCYTOSIS ( 2 patients )
OSTEOPOROTIC FRACTURE ( 2 patients )
NON-SMALL CELL LUNG CANCER STAGE IV ( 2 patients )
COLON CANCER METASTATIC ( 2 patients )
OFF LABEL USE ( 2 patients )
BRAIN NEOPLASM MALIGNANT ( 2 patients )
BONE DECALCIFICATION ( 2 patients )
NEOPLASM PROPHYLAXIS ( 2 patients )
PRIMARY AMYLOIDOSIS ( 2 patients )
SPINAL CORD COMPRESSION ( 2 patients )
DELIRIUM ( 2 patients )
PAIN PROPHYLAXIS ( 2 patients )
CARCINOMA ( 2 patients )
GASTROINTESTINAL NEOPLASM ( 2 patients )
PANCREATIC CARCINOMA ( 2 patients )
LUNG CARCINOMA CELL TYPE UNSPECIFIED STAGE IV ( 2 patients )
MUSCULOSKELETAL DISORDER ( 2 patients )
INTERVERTEBRAL DISCITIS ( 2 patients )
PARAGANGLION NEOPLASM BENIGN ( 2 patients )
RHEUMATIC FEVER ( 2 patients )
HAEMATOPOIETIC NEOPLASM ( 1 patients )
LANGERHANS' CELL HISTIOCYTOSIS ( 1 patients )
PARANEOPLASTIC SYNDROME ( 1 patients )
RIB FRACTURE ( 1 patients )
CHRONIC LYMPHOCYTIC LEUKAEMIA ( 1 patients )
MYELOFIBROSIS ( 1 patients )
ENDOMETRIAL CANCER METASTATIC ( 1 patients )
LARYNGEAL CANCER ( 1 patients )
PELVIC FRACTURE ( 1 patients )
OSTEOSIS ( 1 patients )
PROSTATIC SPECIFIC ANTIGEN INCREASED ( 1 patients )
TREATMENT RELATED SECONDARY MALIGNANCY ( 1 patients )
BLOOD DISORDER ( 1 patients )
FIBROSIS ( 1 patients )
LEUKAEMIA ( 1 patients )
SEXUALLY TRANSMITTED DISEASE ( 1 patients )

Drugs with high FDA adverse event association with PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA:

SOLIRIS (206 patients)
FOLIC ACID (35 patients)
PREDNISOLONE (16 patients)
ZOCOR (15 patients)
ASPIRIN (15 patients)
CYCLOSPORINE (15 patients)
LIPITOR (15 patients)
ADRENERGIC DRUGS (14 patients)
PROSCAR (14 patients)
HYTRIN (14 patients)
ZOMETA (14 patients)
SAW PALMETTO (13 patients)
AREDIA (12 patients)
EXJADE (12 patients)
FUROSEMIDE (11 patients)
VITAMIN E (11 patients)
PREDNISONE (11 patients)
POTASSIUM CHLORIDE (11 patients)
AMBIEN (10 patients)
COPEGUS (10 patients)
METOPROLOL TARTRATE (10 patients)
BLOOD TRANSFUSION, AUXILIARY PRODUCTS (9 patients)
VITAMINS (9 patients)
PREDONINE (9 patients)
UNSPECIFIED MEDICATION (9 patients)
MIRALAX (9 patients)
MULTI-VITAMINS (9 patients)
NPLATE (9 patients)
ADONA (8 patients)
VITAMIN A (8 patients)
AMOXICILLIN (8 patients)
COREG (8 patients)
GLYCYRON (8 patients)
LOTENSIN /00909102/ (8 patients)
NORVASC (8 patients)
ALBUTEROL (7 patients)
COUMADIN (7 patients)
DIOVAN /01319601/ (7 patients)
NEUPOGEN (7 patients)
BENAZEPRIL HYDROCHLORIDE (6 patients)
ROACCUTANE (6 patients)
ECULIZUMAB (6 patients)
STRONG NEO-MINOPHAGEN C (6 patients)
NEORAL (6 patients)
OMEPRAL (6 patients)
ATGAM (5 patients)
AUGMENTIN '125' (5 patients)
CEFTIN (5 patients)
COQ10 (5 patients)
XANAX (5 patients)
GLUCOSAMINE /CHONDROITIN /MSM (5 patients)
LODINE (5 patients)
TYLENOL W/ CODEINE NO. 3 (5 patients)
VICODIN (5 patients)
PERIDEX (5 patients)
ALDACTONE (4 patients)
AMARYL (4 patients)
ATRIPLA (4 patients)
RAMIPRIL (4 patients)
CLONAZEPAM (4 patients)
PROCRIT (4 patients)
COMBIVENT (4 patients)
CRAVIT (4 patients)
DIOVAN (4 patients)
GLAKAY (4 patients)
ICL670A ICL+DISTAB (4 patients)
REMICADE (4 patients)
INTERFERON (4 patients)
RIBAVIRIN (4 patients)
METHYLPREDNISOLONE (4 patients)
NUVARING (4 patients)
OMEPRAZOLE (4 patients)
PEGASYS (4 patients)
ACCUTANE (3 patients)
ACETAMINOPHEN (3 patients)
ALLEGRA (3 patients)
ALLOPURINOL (3 patients)
ASCORBIC ACID (3 patients)
PRILOSEC (3 patients)
CYCLOPHOSPHAMIDE (3 patients)
VINCRISTINE (3 patients)
DESFERAL (3 patients)
SYNTHROID (3 patients)
ENALAPRIL MALEATE (3 patients)
FERROUS SULFATE TAB (3 patients)
HYDROCODONE (3 patients)
PREMARIN (3 patients)
IBUPROFEN (3 patients)
RITUXIMAB (3 patients)
SINGULAIR (3 patients)
LANTUS (3 patients)
SOLU-MEDROL (3 patients)
LEVOTHYROXINE SODIUM (3 patients)
SYMBICORT (3 patients)
MENINGOCOCCAL VACCINES (3 patients)
METFORMIN HCL (3 patients)
MULTI-VITAMIN (3 patients)
NEULASTA (3 patients)
PEGINTERFERON ALFA-2A (3 patients)
PLATELETS (3 patients)
TRAMADOL HCL (2 patients)
ACTHIB/DTP (2 patients)
ACYCLOVIR (2 patients)
ALENDRONATE SODIUM (2 patients)
PROPRANOLOL (2 patients)
THYMOGLOBULIN (2 patients)
BENADRYL (2 patients)
BENAZEPRIL (2 patients)
WELLBUTRIN XL (2 patients)
BIOFERMIN R (2 patients)
TRIAMTERENE AND HYDROCHLOROTHIAZID (2 patients)
BONALON (2 patients)
BONZOL (2 patients)
CAMPATH (2 patients)
CARAFATE (2 patients)
CATLEP (2 patients)
CELEXA (2 patients)
CIPROFLOXACIN (2 patients)
CORDARONE (2 patients)
VITAMEDIN INTRAVENOUS (2 patients)
CORTICOSTEROIDS (2 patients)
DAI-KENCHU-TO (2 patients)
DEFERASIROX (2 patients)
TOPROL-XL (2 patients)
DIGOXIN (2 patients)
ZYRTEC (2 patients)
ZOFRAN (2 patients)
VITAMIN TAB (2 patients)
ENOXAPARIN SODIUM (2 patients)
PRISTIQ (2 patients)
FAMOTIDINE (2 patients)
FENTANYL /00174602/ (2 patients)
FEXOFENADINE HCL (2 patients)
FILGRASTIM (2 patients)
FLOMAX (2 patients)
FONDAPARINUX SODIUM (2 patients)
GABAPENTIN (2 patients)
GAS-X (2 patients)
GASTER D (2 patients)
REGULAR INSULIN (2 patients)
IMUREL (2 patients)
REGLAN (2 patients)
INFLUENZA (2 patients)
PROTONIX (2 patients)
IRINOTECAN HCL (2 patients)
IRON THERAPY (2 patients)
IVIGLOB-EX (2 patients)
LAXOBERON (2 patients)
LEVAQUIN (2 patients)
LOPERAMIDE (2 patients)
PREDNISONE TAB (2 patients)
LOVENOX (2 patients)
LUPRON (2 patients)
TYLENOL (CAPLET) (2 patients)
MAGNESIUM OXIDE (2 patients)
VITAMIN B-12 (2 patients)
SULPERAZON (2 patients)
ZITHROMAX (2 patients)
METHOTREXATE (2 patients)
MINERALIN (2 patients)
MOBIC (2 patients)
MUCINEX (2 patients)
MUCOSTA (2 patients)
MULTIVITAMIN (2 patients)
ZETIA (2 patients)
VITAMIN B12 /00056201/ (2 patients)
NADOLOL (2 patients)
NORCO (2 patients)
PAXIL (2 patients)
PNEUMOCOCCAL POLYSACCHARIDE VACCINE (2 patients)
POLARAMINE (2 patients)
POTASSIUM (2 patients)
ACETYLSALICYLIC ACID (1 patients)
ADVAIR DISKUS 100/50 (1 patients)
ALEMTUZUMAB (1 patients)
ALKERAN (1 patients)
ANTI-THYMOCYTE GLOBULIN RABBIT NOS (1 patients)
ANTIBIOTICS (1 patients)
ANTITHYMOCYTE IMMUNOGLOBULIN (1 patients)
ARANESP (1 patients)
ASACOL (1 patients)
ATORVASTATIN (1 patients)
CALCIUM PLUS VITAMIN D (1 patients)
CALTAN (CALCIUM CARBONATE) (1 patients)
CALTRATE D PLUS MINERALS (1 patients)
CANASA (1 patients)
CENTRUM (1 patients)
CETUXIMAB (1 patients)
CHLORAMPHENICOL (1 patients)
CHLORPROMAZINE HYDROCHLORIDE (1 patients)
CITALOPRAM HYDROBROMIDE (1 patients)
ESTROGENS CONJUGATED (1 patients)
FERO-GRADUMET /00023503/ (FERROUS SULFATE) (1 patients)
FERROUS GLUCONATE (1 patients)
FLUCONAZOLE (1 patients)
FLUDARA (1 patients)
FLUDARABINE PHOSPHATE (1 patients)
FOLATE SODIUM (FOLATE SODIUM) (1 patients)
FOSAMAX (1 patients)
FOSRENOL (1 patients)
GRANULOCYTE COLONY STIMULATING FACTOR (GRANULOCYTE COLONY STIMULATING (1 patients)
HEP-B-VAX (1 patients)
HYDRALAZINE HCL (1 patients)
HYDROCHLOROTHIAZIDE (1 patients)
HYDROXYUREA (1 patients)
METOPROLOL SUCCINATE (1 patients)
NEURONTIN (1 patients)
NEXIUM (1 patients)
NIFEREX (1 patients)
OLANZAPINE (1 patients)

Most common side effects for patients taking ZOMETA:

OSTEONECROSIS (13280 patients)
PAIN (11218 patients)
OSTEONECROSIS OF JAW (9210 patients)
ANXIETY (8240 patients)
BONE DISORDER (8176 patients)
TOOTH EXTRACTION (7047 patients)
OSTEOMYELITIS (5884 patients)
PAIN IN JAW (5666 patients)
INJURY (5173 patients)
ANAEMIA (4897 patients)
BACK PAIN (4875 patients)
FATIGUE (4473 patients)
DYSPNOEA (4327 patients)
IMPAIRED HEALING (4245 patients)
ARTHRALGIA (3931 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (3877 patients)
INFECTION (3751 patients)
DEATH (3699 patients)
PYREXIA (3558 patients)
METASTASES TO BONE (3526 patients)
OSTEOARTHRITIS (3439 patients)
NAUSEA (3300 patients)
FALL (3245 patients)
ANHEDONIA (3155 patients)
DEPRESSION (3151 patients)
DIARRHOEA (3124 patients)
ASTHENIA (3086 patients)
SWELLING (3042 patients)
PNEUMONIA (2933 patients)
NEOPLASM MALIGNANT (2900 patients)
EMOTIONAL DISTRESS (2873 patients)
BONE PAIN (2870 patients)
CONSTIPATION (2855 patients)
SPINAL OSTEOARTHRITIS (2800 patients)
WEIGHT DECREASED (2789 patients)
PLEURAL EFFUSION (2760 patients)
PAIN IN EXTREMITY (2739 patients)
HYPOAESTHESIA (2712 patients)
DEFORMITY (2680 patients)
HYPERTENSION (2615 patients)
OEDEMA PERIPHERAL (2607 patients)
NEUROPATHY PERIPHERAL (2606 patients)
VOMITING (2558 patients)
DIZZINESS (2466 patients)
PRIMARY SEQUESTRUM (2448 patients)
BONE LESION (2417 patients)
CHEST PAIN (2382 patients)
TOOTHACHE (2339 patients)
ATELECTASIS (2304 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (2291 patients)
HEADACHE (2258 patients)
DENTAL CARIES (2215 patients)
DECREASED INTEREST (2208 patients)
INTERVERTEBRAL DISC DEGENERATION (2195 patients)
TOOTH DISORDER (2194 patients)
OSTEOPENIA (2152 patients)
ABDOMINAL PAIN (2056 patients)
HAEMOGLOBIN DECREASED (1960 patients)
DYSPHAGIA (1911 patients)
COUGH (1900 patients)
DEHYDRATION (1861 patients)
CELLULITIS (1840 patients)
PARAESTHESIA (1830 patients)
URINARY TRACT INFECTION (1825 patients)
SINUSITIS (1819 patients)
INTERVERTEBRAL DISC PROTRUSION (1803 patients)
ERYTHEMA (1794 patients)
DECREASED APPETITE (1793 patients)
TOOTH LOSS (1768 patients)
MALAISE (1765 patients)
GAIT DISTURBANCE (1721 patients)
INSOMNIA (1698 patients)
MALIGNANT NEOPLASM PROGRESSION (1675 patients)
TOOTH ABSCESS (1668 patients)
MULTIPLE MYELOMA (1666 patients)
BONE DEBRIDEMENT (1634 patients)
OSTEOPOROSIS (1626 patients)
JAW DISORDER (1620 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (1611 patients)
EXPOSED BONE IN JAW (1606 patients)
BLOOD CREATININE INCREASED (1594 patients)
PURULENT DISCHARGE (1579 patients)
ORAL PAIN (1561 patients)
LYMPHADENOPATHY (1553 patients)
RENAL FAILURE (1542 patients)
BRONCHITIS (1537 patients)
DEEP VEIN THROMBOSIS (1513 patients)
CARDIAC FAILURE CONGESTIVE (1500 patients)
CARDIOMEGALY (1486 patients)
MUSCULOSKELETAL PAIN (1466 patients)
OSTEITIS (1454 patients)
NEOPLASM PROGRESSION (1453 patients)
THROMBOCYTOPENIA (1451 patients)
INFLAMMATION (1444 patients)
HYPOKALAEMIA (1409 patients)
LOOSE TOOTH (1370 patients)
FISTULA (1350 patients)
RIB FRACTURE (1341 patients)
METASTASES TO LIVER (1337 patients)
CONFUSIONAL STATE (1337 patients)
PANCYTOPENIA (1323 patients)
HIATUS HERNIA (1321 patients)
MITRAL VALVE INCOMPETENCE (1316 patients)
NECK PAIN (1305 patients)
HYPOPHAGIA (1299 patients)
DISABILITY (1299 patients)
OSTEOLYSIS (1285 patients)
ARTHRITIS (1266 patients)
EXOSTOSIS (1257 patients)
MYALGIA (1254 patients)
HAEMORRHOIDS (1252 patients)
MASTICATION DISORDER (1242 patients)
PHYSICAL DISABILITY (1237 patients)
MOUTH ULCERATION (1232 patients)
GINGIVITIS (1211 patients)
DEBRIDEMENT (1209 patients)
RASH (1208 patients)
CATARACT (1206 patients)
PERIODONTITIS (1206 patients)
METASTASES TO SPINE (1202 patients)
STOMATITIS (1191 patients)
HYPERLIPIDAEMIA (1191 patients)
RENAL FAILURE ACUTE (1185 patients)
GINGIVAL SWELLING (1157 patients)
SWELLING FACE (1148 patients)
HYPOTENSION (1146 patients)
PATHOLOGICAL FRACTURE (1145 patients)
SEQUESTRECTOMY (1144 patients)
COMPRESSION FRACTURE (1143 patients)
SYNCOPE (1133 patients)
DIVERTICULUM (1131 patients)
GINGIVAL PAIN (1127 patients)
RENAL CYST (1119 patients)
VISION BLURRED (1102 patients)
LUNG NEOPLASM (1100 patients)
TOOTH FRACTURE (1092 patients)
ATRIAL FIBRILLATION (1087 patients)
ENDODONTIC PROCEDURE (1086 patients)
JAW OPERATION (1081 patients)
MUSCULAR WEAKNESS (1072 patients)
TRICUSPID VALVE INCOMPETENCE (1067 patients)
TOOTH INFECTION (1067 patients)
MUSCLE SPASMS (1066 patients)
ORAL DISORDER (1052 patients)
HERPES ZOSTER (1018 patients)
OSTEOSCLEROSIS (1016 patients)
NEUTROPENIA (1013 patients)
UPPER RESPIRATORY TRACT INFECTION (1004 patients)
DENTAL OPERATION (1002 patients)
SEPSIS (996 patients)
SCOLIOSIS (991 patients)
METASTASES TO LUNG (990 patients)
ASEPTIC NECROSIS BONE (983 patients)
CHILLS (975 patients)
SURGERY (972 patients)
PERIODONTAL DISEASE (972 patients)
OEDEMA (965 patients)
GINGIVAL DISORDER (953 patients)
PULMONARY EMBOLISM (945 patients)
GASTRITIS (932 patients)
DYSURIA (927 patients)
DISCOMFORT (924 patients)
CORONARY ARTERY DISEASE (913 patients)
RED BLOOD CELL COUNT DECREASED (907 patients)
ACTINOMYCOSIS (902 patients)
CHOLELITHIASIS (898 patients)
HAEMATOCRIT DECREASED (895 patients)
GINGIVAL INFECTION (887 patients)
RENAL FAILURE CHRONIC (882 patients)
BURSITIS (870 patients)
NEPHROLITHIASIS (870 patients)
PLATELET COUNT DECREASED (870 patients)
HEPATIC STEATOSIS (860 patients)
ABSCESS (855 patients)
ARTERIOSCLEROSIS (848 patients)
CONTUSION (847 patients)
PROSTATIC SPECIFIC ANTIGEN INCREASED (840 patients)
GINGIVAL BLEEDING (836 patients)
HAEMATURIA (832 patients)
LIFE EXPECTANCY SHORTENED (825 patients)
METASTASES TO CENTRAL NERVOUS SYSTEM (821 patients)
DYSPNOEA EXERTIONAL (818 patients)
WHITE BLOOD CELL COUNT DECREASED (814 patients)
SPINAL COMPRESSION FRACTURE (809 patients)
LUNG INFILTRATION (808 patients)
TENDERNESS (808 patients)
DISEASE PROGRESSION (807 patients)
ABDOMINAL PAIN UPPER (801 patients)
BLOOD GLUCOSE INCREASED (797 patients)
DIVERTICULUM INTESTINAL (789 patients)
DYSPEPSIA (781 patients)
JAW FRACTURE (781 patients)
BLOOD ALKALINE PHOSPHATASE INCREASED (778 patients)
RECTAL HAEMORRHAGE (774 patients)
MENTAL STATUS CHANGES (773 patients)
ROTATOR CUFF SYNDROME (771 patients)
EMPHYSEMA (770 patients)
LUMBAR SPINAL STENOSIS (770 patients)
LEUKOPENIA (768 patients)
HYPOCALCAEMIA (761 patients)
JOINT SWELLING (757 patients)
HYPONATRAEMIA (753 patients)
MUSCULOSKELETAL CHEST PAIN (752 patients)
BONE DENSITY DECREASED (746 patients)
ABSCESS JAW (740 patients)
DYSGEUSIA (735 patients)
RESPIRATORY FAILURE (726 patients)
HOT FLUSH (725 patients)
DIABETES MELLITUS (723 patients)
DRY MOUTH (721 patients)

In addition to reviewing our up-to-date FDA research, users may interact with the FactMed community - currently one million members and growing! FactMed online research and discussions are read by patients, scientists, physicians, and other interested health care parties. Post follow up Questions to learn from our diverse readership. Likewise, patients who have experienced unwanted effects are encouraged to share their Concerns to help educate and inform our members.

Recent FactMed Activity for ZOMETA

Issue	Description / Topic	Timestamp
QUESTION NIGHT SWEATS	What gives more night sweats....Zometa or Prolia	2015-01-09 07:10:11
QUESTION HAEMOGLOBIN DECREASED	Shingles after Zobone and Herceptin. Is this a side effect. Having shingles every 2 to 3 months .zobone every 6 weeks and Herceptin every 3 weeks.	2015-04-02 04:06:17
CONCERN HAEMOGLOBIN DECREASED	Shingles every 2 months. Meds Herceptin x 3 weeks Zobone 6 weekly. Is there a connection?	2015-04-02 04:12:05
CONCERN NEPHROGENIC ANAEMIA	I think the admin of this web page is actually working hard in support of his web site, since here every stuff is quality based material. �?��?��?��?��??�?�財�?�?つ�??�??�?��??, �?��?��?��?��??�?��??�??�?�財�?�?��??�?�,	2015-06-30 16:08:21
QUESTION MACULAR DEGENERATION	Is zometa contraindicated for a patient who is already diagnosed with macular degeneration, since macular degeneration was found to be a side effect in 0.34% of patients?	2015-07-24 11:39:08
QUESTION CHONDROSIS	I am wondering if my painful Chondrosis is from taking Prolea	2015-08-14 07:47:18
QUESTION BLOOD ALKALINE PHOSPHATASE INCREASED	I was given zometa with my last herceptin dose 13 days ago. 24 hours later I was hospitalized with high fever and uti and low white cell count. I was given antibiotics a neupogen shot and sent home. Now I have a sore on the back of my throat a high esr result and elevated alkaline phosphates leves. Are these possible side effects to zometa	2015-12-05 09:12:24
QUESTION TRIGGER FINGER	I am having trigger finger of thumb since 3 weeks for which I am taking treatment. I am due for zometa which is prescribed for osteopaenia can I take the infusion?	2017-02-08 02:09:57
QUESTION INSOMNIA	Mike,Depende onde se bate o pontapÃ©. Se for ainda perto da Ã¡rea e se o objectivo e adiantar muito a linha defensiva, o defesa ainda tem que avanÃ§ar uns bons metros. Mas concordo que tem a sua dose de risco, nÃ£o sei se ju.atficidosFCS	2017-03-20 07:23:05
QUESTION BONE DISORDER	Thanks so much, Brenda. It’s one of those 028special treat” dishes with the large chunk of truffle cheese inside. Such a great surprise to find when you slice into it.	2017-03-20 08:39:13
QUESTION SPINAL OSTEOARTHRITIS	INDICATORE FTSEMIB/FIBSPDomanda per Mir: dal tuo commento del 26 sembra che tu il 24 non sia entrato su;ia#8217lindlc&tore anche se [nota del moderatore: omesso livello segnale che Ã¨ riservato area trading] , se cosÃ¬ fosse come mai? Grazie!!! Ed un saluto a tutti!!!	2017-03-20 10:42:47
QUESTION CELLULITIS	Pues va a ser que no es broma. Si se paga por tocar los pasodobles taurinos, Calanda tendrÃ¡ que aflojar la mosca. No aflojarla serÃa el nuevo "milagro de Caaodnl&quat;.	2017-03-20 10:45:16
QUESTION PSOAS SIGN	dqyc6chxm59xpcg2f0	2017-06-18 22:23:47

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