Is MACULAR ISCHAEMIA a side effect of glipizide ? ( FactMed.com )

About this FactMed analysis covering adverse side effect reports of glipizide patients who developed MACULAR ISCHAEMIA.

FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 1 individuals taking glipizide reported MACULAR ISCHAEMIA to the FDA. A total of 17985 glipizide drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication.

FDA Research Report

Introduction This page is designed to help you determine the relationship, if any, between glipizide and MACULAR ISCHAEMIA. In doing so, we compare glipizide with other drugs that cause MACULAR ISCHAEMIA, to help you evaluate whether or not glipizide causes MACULAR ISCHAEMIA. Likewise, this page shows the most highly-reported side effects of glipizide, so you can see if MACULAR ISCHAEMIA ranks among glipizide's most well-known side effects.

Summary Statistics
Reports of glipizide causing MACULAR ISCHAEMIA: 1
Reports of any side effect of glipizide : 17985
Percentage of glipizide patients where MACULAR ISCHAEMIA is a reported side effect: 0.0056%

FDA reports of any drug causing MACULAR ISCHAEMIA : 45
Average percentage for all medicated patients where MACULAR ISCHAEMIA is reported as a complication: 0.0003%

Physician opinion on glipizide as adverse event culprit:

Overall opinion for all reports of this drug:

Most frequent diagnoses/indications for prescribing glipizide:

DIABETES MELLITUS ( 2247 patients )
TYPE 2 DIABETES MELLITUS ( 832 patients )
PRODUCT USED FOR UNKNOWN INDICATION ( 588 patients )
DRUG USE FOR UNKNOWN INDICATION ( 569 patients )
DIABETES MELLITUS NON-INSULIN-DEPENDENT ( 137 patients )
ILL-DEFINED DISORDER ( 45 patients )
BLOOD GLUCOSE INCREASED ( 43 patients )
BLOOD GLUCOSE ABNORMAL ( 26 patients )
HYPERGLYCAEMIA ( 14 patients )
TYPE 1 DIABETES MELLITUS ( 11 patients )
ACCIDENTAL POISONING ( 10 patients )
INSULIN-REQUIRING TYPE 2 DIABETES MELLITUS ( 10 patients )
DIABETES MELLITUS INSULIN-DEPENDENT ( 9 patients )
BLOOD GLUCOSE ( 9 patients )
GLUCOSE TOLERANCE IMPAIRED ( 8 patients )
HYPERTENSION ( 6 patients )
MUSCLE SPASMS ( 5 patients )
INSULIN-REQUIRING TYPE II DIABETES MELLITUS ( 4 patients )
RHEUMATOID ARTHRITIS ( 4 patients )
ACCIDENTAL EXPOSURE ( 4 patients )
CARDIAC DISORDER ( 4 patients )
DIABETES MELLITUS INADEQUATE CONTROL ( 3 patients )
DRUG THERAPY ( 3 patients )
TRANSPLANT REJECTION ( 2 patients )
INTENTIONAL OVERDOSE ( 2 patients )
OEDEMA ( 2 patients )
BLOOD GLUCOSE DECREASED ( 2 patients )
RENAL FAILURE ( 2 patients )
COMPLETED SUICIDE ( 2 patients )
DRUG ABUSE ( 1 patients )
PROPHYLAXIS AGAINST TRANSPLANT REJECTION ( 1 patients )
GLYCOSYLATED HAEMOGLOBIN INCREASED ( 1 patients )
BLOOD TRIGLYCERIDES INCREASED ( 1 patients )
CARDIOVASCULAR DISORDER ( 1 patients )
HYPOGLYCAEMIA ( 1 patients )
DEPRESSION ( 1 patients )
DIABETES MELLITUS MANAGEMENT ( 1 patients )
DIABETIC NEUROPATHY ( 1 patients )
PROPHYLAXIS ( 1 patients )
BLOOD PRESSURE ( 1 patients )
SUICIDAL IDEATION ( 1 patients )
HEPATITIS C ( 1 patients )
( 0 patients )

Drugs with high FDA adverse event association with MACULAR ISCHAEMIA:

ASPIRIN (9 patients)
AVASTIN (9 patients)
CEFUROXIME (8 patients)
RANIBIZUMAB (6 patients)
CEFUROXIME SODIUM (5 patients)
LIPITOR (5 patients)
INSULIN (4 patients)
LUCENTIS (4 patients)
OPTIMARK (4 patients)
ACTOS (3 patients)
CLONIDINE (3 patients)
COZAAR (3 patients)
HORMONES NOS (3 patients)
HUMULIN R (3 patients)
LEVAQUIN (3 patients)
ACULAR (2 patients)
AMBIEN (2 patients)
ANTIDIABETIC DRUG NOS (2 patients)
CIALIS (2 patients)
EFFEXOR (2 patients)
EPOGEN (2 patients)
FLAGYL (2 patients)
GENTAMICIN SULFATE (WATSON LABORATORIES) (2 patients)
HYDROCHLOROTHIAZIDE (2 patients)
IMDUR (2 patients)
ISORDIL (2 patients)
KINEDAK (2 patients)
LANTUS (2 patients)
LOPRESSOR (2 patients)
METANX (2 patients)
METOPROLOL TARTRATE (2 patients)
NITROFUR (2 patients)
PERCOCET (2 patients)
PHOSLO (2 patients)
PREVACID (2 patients)
PROCARDIA XL (2 patients)
REGLAN (2 patients)
RENAGEL /01459901/ (2 patients)
SENOKOT (2 patients)
TRAMADOL HCL (2 patients)
TRASTUZUMAB (2 patients)
VISUDYNE (2 patients)
ZAROXOLYN (2 patients)
(ANESTHETICS) (1 patients)
ACETOZOLAMIDE (1 patients)
ADRENALIN IN OIL INJ (1 patients)
ALDACTONE (1 patients)
ALLEGRA (1 patients)
ALPRAZOLAM (1 patients)
AMARYL (1 patients)
AMIKACIN (1 patients)
AMITIZA (1 patients)
AMOXICILLIN (1 patients)
ARMOUR (1 patients)
ATENOLOL (1 patients)
AVANDIA (1 patients)
AZITHROMYCIN (1 patients)
AZOR (1 patients)
BACITRACIN (1 patients)
BENAZEPRIL HCL (1 patients)
BENICAR (1 patients)
BEVACIZUMAB (1 patients)
BYETTA (1 patients)
CEFUROXIME (NO PREF. NAME) (1 patients)
CELEXA (1 patients)
CEPHALEXIN (1 patients)
CERAXON (CITICOLINE) (1 patients)
CHERATUSSIN (1 patients)
CIPROFLOXACIN (1 patients)
CITRACAL CALCIUM CITRATE WITH VITAMIN D (1 patients)
CLARITHROMYCIN (1 patients)
CLINDAMYCIN (1 patients)
CLINDESSE (1 patients)
CLONAZEPAM (1 patients)
COREG (1 patients)
COUMADIN (1 patients)
CYCLOBENZAPR (1 patients)
CYTOFLAVIN (INOSINE + NICOTINAMIDE + RIBOFLAVIN MONONUCLEOTIDE + SUCCI (1 patients)
DEXAMETHASONE (1 patients)
DIAMOX (1 patients)
DIGOXIN (1 patients)
DIOVAN (1 patients)
DIPHEN/ATROP (1 patients)
DOFAMINE (1 patients)
DOXYCYCL HYC (1 patients)
EQUATE STOOL SOFTENER WITH STIMULANT LAXATIVE (1 patients)
ERYTHROMYCIN (1 patients)
EXENATIDE 10MCG PEN, DISPOSABLE DEVICE (EXENATIDE PEN (10MCG)) PEN,DIS (1 patients)
FLAVOXATE HYDROCHLORIDE COATED TAB (1 patients)
FLEXERIL (1 patients)
FLUCONAZOLE (1 patients)
FRAGMIN (1 patients)
GAMMA-HYDROXYBUTYRIC ACID (1 patients)
GLIPIZIDE (1 patients)
GUAIFENEX (1 patients)
GUIADEX (1 patients)
HEMOHES (1 patients)
HUMALOG (1 patients)
HYDRALAZINE (1 patients)
HYDRALAZINE HCL (1 patients)
HYDROCODONE (1 patients)
HYDROXYCHLOROQUINE (1 patients)
HYDROXYZ HCL (1 patients)
HYOSCYAMINE (1 patients)
IBUPROFEN (1 patients)
J-TAN D (1 patients)
KETEK (1 patients)
LASIX (1 patients)
LIDOCAINE W/ EPINEPHRINE (1 patients)
LISINOPRIL (1 patients)
LORAZEPAM (1 patients)
LOTEMAX (1 patients)
LOTREL (1 patients)
MARCAINE (1 patients)
MARZULENE S (1 patients)
MECLIZINE (1 patients)
METANK (1 patients)
METFORMIN HCL (1 patients)
METHYLPRED (1 patients)
MIDAZOLAM (1 patients)
MULTI-VITAMIN (1 patients)
MYTUSSIN (1 patients)
NASONEX (1 patients)
NEVANAC (1 patients)
NEXIUM (1 patients)
NIACIN (1 patients)
NITROFURANTOIN (1 patients)
NOVOLOG (1 patients)
ODANSETRON (1 patients)
OMEGA FISH OIL 3 (1 patients)
OMEZ (1 patients)
OPTIVA (1 patients)
PARACETAMOL (1 patients)
PERFTORAN (1 patients)
PLAVIX (1 patients)
PREDNISOLONE (1 patients)
PREDNISONE (1 patients)
PREMARIN (1 patients)
PRILOSEC (1 patients)
PROCHLORPER (1 patients)
PROLIX (1 patients)
PROMETRIUM (1 patients)
PROPO-N/APAP (1 patients)
PROVENTIL-HFA (1 patients)
REFRESH (1 patients)
RENIVACE (1 patients)
RESTASIS (1 patients)
RISAQUAD (1 patients)
SINGULAIR (1 patients)
SODIUM OXYBATE (1 patients)
TAMIFLU (1 patients)
TERBINAFINE HCL (1 patients)
TERCONAZOLE (1 patients)
TRIAMCINOLONE ACETONIDE (1 patients)
TRIMETHOBENZ (1 patients)
TRIMETHOPRIM (1 patients)
UROXATRAL (1 patients)
VAZOTAN (1 patients)
VENLAFAXINE (1 patients)
VERAMYST (1 patients)
VERAPAMIL (1 patients)
VI-Q-TUSS SYRUP (1 patients)
VIAGRA (1 patients)
VITAMIN B-12 (1 patients)
VIVELLE-DOT (1 patients)
XALATAN (1 patients)
XANAX (1 patients)
ZITHROMAX (1 patients)
ZYRTEC (1 patients)

Most common side effects for patients taking glipizide:

BLOOD GLUCOSE INCREASED (3052 patients)
NAUSEA (2064 patients)
WEIGHT DECREASED (1414 patients)
DYSPNOEA (1145 patients)
VOMITING (1122 patients)
DIZZINESS (1110 patients)
BLOOD GLUCOSE DECREASED (1076 patients)
PAIN (1052 patients)
DIARRHOEA (1045 patients)
ASTHENIA (1038 patients)
FATIGUE (991 patients)
DRUG INEFFECTIVE (976 patients)
CARDIAC FAILURE CONGESTIVE (963 patients)
MYOCARDIAL INFARCTION (895 patients)
DECREASED APPETITE (891 patients)
ANXIETY (764 patients)
HEADACHE (763 patients)
OEDEMA PERIPHERAL (725 patients)
FALL (681 patients)
ANAEMIA (662 patients)
CHEST PAIN (652 patients)
HYPOGLYCAEMIA (620 patients)
RENAL FAILURE (581 patients)
PNEUMONIA (571 patients)
DIABETES MELLITUS (571 patients)
HYPERTENSION (571 patients)
RENAL FAILURE ACUTE (552 patients)
CEREBROVASCULAR ACCIDENT (531 patients)
BACK PAIN (522 patients)
DEPRESSION (519 patients)
PAIN IN EXTREMITY (499 patients)
HYPOTENSION (498 patients)
WEIGHT INCREASED (493 patients)
INJURY (488 patients)
ARTHRALGIA (485 patients)
CORONARY ARTERY DISEASE (481 patients)
CONSTIPATION (473 patients)
PYREXIA (456 patients)
DEATH (455 patients)
TREMOR (454 patients)
DEHYDRATION (449 patients)
ABDOMINAL PAIN (446 patients)
MALAISE (446 patients)
ATRIAL FIBRILLATION (444 patients)
ABDOMINAL PAIN UPPER (414 patients)
COUGH (414 patients)
FEELING ABNORMAL (405 patients)
HYPERHIDROSIS (398 patients)
INSOMNIA (397 patients)
PRURITUS (396 patients)
CONFUSIONAL STATE (372 patients)
URINARY TRACT INFECTION (372 patients)
GAIT DISTURBANCE (357 patients)
RASH (356 patients)
EMOTIONAL DISTRESS (332 patients)
DIABETES MELLITUS INADEQUATE CONTROL (313 patients)
PANCREATITIS (312 patients)
GASTROOESOPHAGEAL REFLUX DISEASE (306 patients)
HYPOAESTHESIA (305 patients)
DYSPEPSIA (302 patients)
FLUSHING (301 patients)
TYPE 2 DIABETES MELLITUS (300 patients)
ANHEDONIA (295 patients)
SEPSIS (285 patients)
SYNCOPE (285 patients)
VISION BLURRED (281 patients)
SOMNOLENCE (281 patients)
MYALGIA (277 patients)
LOSS OF CONSCIOUSNESS (273 patients)
MUSCLE SPASMS (272 patients)
PLEURAL EFFUSION (272 patients)
DRUG EFFECT DECREASED (271 patients)
CARDIAC DISORDER (268 patients)
BLOOD CREATININE INCREASED (266 patients)
ABDOMINAL DISTENSION (264 patients)
HAEMOGLOBIN DECREASED (262 patients)
CONDITION AGGRAVATED (256 patients)
PALPITATIONS (256 patients)
INJECTION SITE PAIN (255 patients)
CONVULSION (254 patients)
PARAESTHESIA (252 patients)
BLOOD PRESSURE INCREASED (244 patients)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (242 patients)
DRUG INTERACTION (238 patients)
DYSPHAGIA (238 patients)
MENTAL STATUS CHANGES (238 patients)
MUSCULAR WEAKNESS (229 patients)
HYPERGLYCAEMIA (228 patients)
RESPIRATORY FAILURE (225 patients)
MITRAL VALVE INCOMPETENCE (224 patients)
ERYTHEMA (223 patients)
UNEVALUABLE EVENT (222 patients)
NEUROPATHY PERIPHERAL (219 patients)
CHILLS (218 patients)
CARDIAC ARREST (217 patients)
OEDEMA (213 patients)
INCORRECT DOSE ADMINISTERED (212 patients)
BRONCHITIS (205 patients)
OSTEOARTHRITIS (202 patients)
BLOOD GLUCOSE FLUCTUATION (202 patients)
HYPERLIPIDAEMIA (202 patients)
ECONOMIC PROBLEM (200 patients)
BALANCE DISORDER (199 patients)
CELLULITIS (198 patients)
CONTUSION (197 patients)
OSTEONECROSIS OF JAW (196 patients)
ACUTE MYOCARDIAL INFARCTION (196 patients)
ABDOMINAL DISCOMFORT (195 patients)
NERVOUSNESS (189 patients)
HYPERKALAEMIA (188 patients)
GLYCOSYLATED HAEMOGLOBIN INCREASED (186 patients)
PHARMACEUTICAL PRODUCT COMPLAINT (186 patients)
STRESS (185 patients)
HYPERSENSITIVITY (183 patients)
INFECTION (182 patients)
RENAL FAILURE CHRONIC (182 patients)
COMPLETED SUICIDE (180 patients)
BLOOD CHOLESTEROL INCREASED (179 patients)
ANOREXIA (178 patients)
THROMBOCYTOPENIA (173 patients)
GASTROINTESTINAL HAEMORRHAGE (173 patients)
SINUSITIS (172 patients)
HEART RATE INCREASED (172 patients)
CARDIOMEGALY (171 patients)
DEEP VEIN THROMBOSIS (168 patients)
LETHARGY (167 patients)
TRANSIENT ISCHAEMIC ATTACK (166 patients)
FLATULENCE (166 patients)
INTERNATIONAL NORMALISED RATIO INCREASED (165 patients)
MEMORY IMPAIRMENT (163 patients)
RENAL IMPAIRMENT (160 patients)
HYPOKALAEMIA (160 patients)
PANCYTOPENIA (158 patients)
FEAR (158 patients)
MULTI-ORGAN FAILURE (157 patients)
MEDICATION ERROR (155 patients)
PULMONARY EMBOLISM (155 patients)
CARDIO-RESPIRATORY ARREST (155 patients)
ARRHYTHMIA (154 patients)
CHOLELITHIASIS (154 patients)
ATELECTASIS (154 patients)
GENERAL PHYSICAL HEALTH DETERIORATION (153 patients)
ARTHRITIS (153 patients)
TREATMENT NONCOMPLIANCE (149 patients)
CORONARY ARTERY OCCLUSION (149 patients)
CHEST DISCOMFORT (148 patients)
VISUAL ACUITY REDUCED (148 patients)
GASTRITIS (148 patients)
DYSGEUSIA (147 patients)
DIABETIC NEUROPATHY (147 patients)
NASOPHARYNGITIS (144 patients)
INJECTION SITE HAEMORRHAGE (143 patients)
INJECTION SITE BRUISING (143 patients)
FLUID RETENTION (143 patients)
SINUS TACHYCARDIA (143 patients)
BRADYCARDIA (142 patients)
MUSCULOSKELETAL PAIN (142 patients)
RECTAL HAEMORRHAGE (142 patients)
OSTEOMYELITIS (141 patients)
HAEMATURIA (140 patients)
DYSPNOEA EXERTIONAL (140 patients)
FEELING HOT (139 patients)
RENAL INJURY (138 patients)
BLOOD UREA INCREASED (138 patients)
RENAL DISORDER (137 patients)
HYPONATRAEMIA (137 patients)
OVERDOSE (136 patients)
PULMONARY OEDEMA (136 patients)
MYOCARDIAL ISCHAEMIA (136 patients)
URTICARIA (136 patients)
TRICUSPID VALVE INCOMPETENCE (135 patients)
JOINT SWELLING (134 patients)
PLATELET COUNT DECREASED (134 patients)
CARDIOMYOPATHY (134 patients)
THROMBOSIS (132 patients)
HYPOPHAGIA (130 patients)
PULMONARY HYPERTENSION (130 patients)
DEFORMITY (130 patients)
PANCREATITIS ACUTE (128 patients)
ANGINA PECTORIS (127 patients)
NECK PAIN (126 patients)
SWELLING (126 patients)
ASTHMA (125 patients)
SPINAL OSTEOARTHRITIS (125 patients)
ERECTILE DYSFUNCTION (125 patients)
VISUAL IMPAIRMENT (124 patients)
DRY MOUTH (124 patients)
RHINORRHOEA (123 patients)
EPISTAXIS (122 patients)
FEELING JITTERY (120 patients)
TOOTH EXTRACTION (117 patients)
CARDIAC FAILURE (117 patients)
ALANINE AMINOTRANSFERASE INCREASED (117 patients)
RHABDOMYOLYSIS (117 patients)
ERUCTATION (117 patients)
SWELLING FACE (117 patients)
OFF LABEL USE (116 patients)
BLOOD GLUCOSE ABNORMAL (116 patients)
PERIPHERAL VASCULAR DISORDER (115 patients)
DYSURIA (115 patients)
POLLAKIURIA (115 patients)
MULTIPLE INJURIES (115 patients)
LUNG INFILTRATION (114 patients)
BLOOD PRESSURE DECREASED (114 patients)
NEPHROLITHIASIS (114 patients)
CATARACT (113 patients)
HYPOXIA (112 patients)
HAEMATOCHEZIA (111 patients)
EXOSTOSIS (111 patients)
HAEMATOCRIT DECREASED (111 patients)

In addition to reviewing our up-to-date FDA research, users may interact with the FactMed community - currently one million members and growing! FactMed online research and discussions are read by patients, scientists, physicians, and other interested health care parties. Post follow up Questions to learn from our diverse readership. Likewise, patients who have experienced unwanted effects are encouraged to share their Concerns to help educate and inform our members.

Recent FactMed Activity for glipizide

Issue	Description / Topic	Timestamp
QUESTION BACTERIAL SEPSIS	E para que serve este medicamento	2015-04-01 22:31:30
QUESTION PLATELET COUNT INCREASED	I have been taking glipizide for a year now and my last blood work showed elevated platelet count. My RBC and WBC are in the normal range though. My doctor suspects the glipizide causes stress in my body when I get hypoglycemic so my body is fighting it. Does anyone think this could be true?	2015-04-09 12:17:27
QUESTION HEPATORENAL SYNDROME	My sister is in hepatorenal failure. Her A1c is 5, blood sugars running 200 to 300. Doctor put her back on glipizide, is this going to exacerbate hepatorenal failure.	2015-04-29 22:55:19
QUESTION EYE PAIN	Ways of dealing with eye pain?	2015-06-20 20:08:32
QUESTION URINE FLOW DECREASED	Since taking glipizide I seem to be gaining weight and I am not urinating as frequently as prior to taking the medication and my urine flow at times seems to be getting weaker	2015-08-01 15:54:42
QUESTION HEPATITIS C	I have recently beend diagnosed and treated successfully for HepC. Will Glipizide put me at risk for a re-occurence?	2016-01-03 14:19:54
QUESTION BLOOD AMINO ACID LEVEL DECREASED	I am on Glipizide 5 mg oral for type 2 diabetic condition. I have 2 or more soft stools per day now. Lopermide not working vey well an suggestions?	2016-01-18 13:53:55
QUESTION EXPIRED DRUG ADMINISTERED	My glipizide is expired by a month will it still work if I take it	2016-02-14 22:57:07
QUESTION WEIGHT INCREASED	How many times a day y Should you take this pill	2016-03-01 19:35:19
QUESTION COUGH	Is coughing, like a dry cough a side effect from takim glipizide	2016-05-15 18:10:40
QUESTION GLOMERULAR FILTRATION RATE DECREASED	On 2.5mg glipizide doing great but Nephrologist doubled dose to 5mg, in one month my gfr dropped to 22 from 24 where it had been stable for six months. My glucose did NOT change. Could the glipizide increase cause the gfr to drop like this ? I have many other medical issues.	2016-06-22 15:38:09
QUESTION PANIC ATTACK	I've eliminated everything but glipizide. Has to be the culprit of panic attacks for last 5 months	2016-08-01 18:34:29
QUESTION KIDNEY INFECTION	Can glipizide cause kidney infection	2016-09-07 19:44:42
QUESTION PLATELET COUNT INCREASED	I have been taking glipizide for 18 months and now have a high platelet count, is there any connection?	2016-10-17 14:49:49
QUESTION ACNE	I stopped taking my gemfribozil as advised by my doctor because of something that looks like acne and hurts. I noticed It began around the bottom and behind my ears. I have been off the med for almost a week but I suspect the glipizide I did read up on gemfribozil and it causes rash , is there issues with gemfribozil too ?	2016-11-06 09:51:30
QUESTION PLATELET COUNT ABNORMAL	Have been taking Glipizide for 3 years, low platelet count was 109, doctor took me off glipizide would that cause low platelet?	2017-02-27 21:14:39
QUESTION PLATELET COUNT ABNORMAL	Have been taking Glipizide for 3 years, low platelet count was 109, doctor took me off glipizide would that cause low platelet?	2017-02-27 21:16:17
QUESTION LYMPHOMA	My husband has been on glipizide ,for his type 2 diabetes,for about two years.he also had a MRI in January to evaluate his spinal stenosis and sciatica pain.from this MRI,he had an incidental finding of small cell b lymphoma at the sacrum level.he has no symptoms of lymphoma.could the glipizide be a contributing factor to the lymphoma.	2017-05-02 12:37:28
QUESTION WHEELCHAIR USER	x64e3yvzoxlukr03gl	2017-06-19 03:21:12

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